Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
GNA14 GNA11 â—¼   GTPASE_REACTION ✅ 2.0 0.8 Reactome 8073283 7937899
GNA14 GNAQ â—¼   GTPASE_REACTION ✅ 2.0 0.8 Reactome 8073283 7937899
GNA14 GNA15 â—¼   GTPASE_REACTION ✅ 2.0 0.8 Reactome 8073283 7937899
BDKRB2 SLC35A4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
BDKRB2 SYNGR2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
BDKRB2 AATK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
GNAQ AGTR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219925 17498700
BDKRB2 AGTR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
AGTR1 GNA12 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
AGTR1 AP2M1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
BDKRB2 AP2M1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
BDKRB2 PEX16 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
BDKRB2 TPI1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
BDKRB2 SLC2A8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
BDKRB2 TMEM11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
BDKRB2 NIF3L1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
BDKRB2 TMEM70 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
BDKRB2 SYNE1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
BDKRB2 EFS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
BDKRB2 HERC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
BDKRB2 CLCA4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
BDKRB2 INF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
BDKRB2 SPG7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
BDKRB2 USP4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
BDKRB2 CD81 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
BDKRB2 CD82 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
TP53 BDKRB2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15632413 10748162
TP53 BDKRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
BDKRB2 NOS3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10510297 10681501
GNAO1 CALR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TP53 CD82 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
EP300 CREBBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23403292 24998469
TP53 CREBBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 10823891 5212595
SRC EFS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
TP73 EP300 â—¼   ACETYLATION ✅ 2.0 0.8 intact 11804596 5215037
GNA11 GNAQ â—¼   GTPASE_REACTION ✅ 2.0 0.8 Reactome 8073283 7937899
GNA11 GNA15 â—¼   GTPASE_REACTION ✅ 2.0 0.8 Reactome 8073283 7937899
GNA15 GNAQ â—¼   GTPASE_REACTION ✅ 2.0 0.8 Reactome 8073283 7937899
TP53 NOS3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18431400
TP53 TFAP2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18980971 16636674
TP73 TP63 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19815500 0905867106
CD81 GNA13 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 32900848 30024968
CD81 GNAI3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 32900848 30024968
CD81 GNAI1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 32900848 30024968
EFS SRC â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 8647432 17474147
AGTR1 GRK5 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 9211925 8662816
PECAM1 SRC â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
CD81 GNA11 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 32900848 30024968
SRC EP300 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 26695438 10973497
GNAI1 GNAI3 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
EP300 TP73 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
TP53 TP63 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
SRC PECAM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12775720 10858437
GNA14 GRK2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 10567430 16339447 10727532
GRK2 GNA11 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 10567430 16339447 10727532
GRK2 GNAQ â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 10567430 16339447 10727532
GRK2 GNA15 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 10567430 16339447 10727532
AGTR1 GNAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17498700 31160049 11313903
TFAP2A CREBBP â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 12586840 11694877 11744733
TFAP2A CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12586840 12169688 17905638
KNG1 NOS3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18758513 22155161 11470796
TP73 TP63 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16413471 21436470 18026135
TP73 TP63 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11238924 19815500 10373484
EP300 TP53 â—¼   POLYUBIQUITINATION ✅ - 0.91 0.91 Signor 12690203
TP53 EP300 â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 16611888 6599495
CREBBP TP53 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
EP300 TP53 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
SRC GRK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 12624098 16725308 11278940 11566877 16189514
PRKCD GRK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11042191
GRK2 BDKRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 11517230
GRK2 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 15116093 20473327 23723076 18952844 15053879 10933801 33256128 11409876 20124405 29988038 14729628
GRK3 BDKRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 11517230
KNG1 BDKRB2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 18127230 3366244 8063797 1314587
GRK4 BDKRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 11517230
SRC BDKRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10085087 16226010
PRKCD BDKRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 11517230
GRK6 BDKRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 11517230
GRK5 BDKRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 11517230
KNG1 BDKRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 9203620 8063797 8302267 28966616
TP53 CD82 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 12527206 12474542 9736732 12806379 11895916 15580298 10828889
TP73 CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10648616 21245298 11172610 10435630
TP53 CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 19057620 15632413 11466559 19448667 19880525 9891054 22198284 10833421 11709699 10435630 11390631 9890939 21191649 12501250 11928223 17434128 12164786 24330748 11779500 10435595 21513889 10777477
CREBBP TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 49.0 1.0 Omnipath 17303408 25545885 27618436 19220000 16713569 10823891 15632413 19805293 25451029 15279786 10473588 12154097 7575488 16537920 10848610 18485870 19880525 10648616 20144767 14722092 14759370 18590585 26976603 9194564 19788416 25314079 19166313 12426395 9288775 11782467 17660363 19234109 21390126 10196247 17434128 19357310 10551785 22084066
PRKCD EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 11020388 17434128 12379484 15006641 18053091 15212693 12590608
EP300 TP73 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 11804596 19407812 15175157 19788416 12660246 19218448 10648616 15454570 16998810 25675294 15893728 18663001
EP300 TP63 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15965232
EP300 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 137.0 1.0 Omnipath 11907332 25545885 21187340 10706102 16438982 10490106 19339993 15542844 23010591 11433299 19608861 17438265 17906639 16024799 9194564 20234175 23402884 12162806 26229107 16959611 15186775 9744860 11070080 17977830 17189186 22266186 20228809 15664194 19805293 25753752 11804596 26625199 27818144 10648616 16928824 9288740 10942770 12724314 23148227 23728348 15965232 19218448 16678111 16782091 20094059 14612423 24821727 10518217 16713569 9891054 25288747 17452980 14759370 19788416 25156994 18931695 22074660 23880760 15337767 15509808 26302407 22731250 18391200 16543236 19234109 21471221 23307557 25867071 12690203 15558054 18612383 23870121 18243116 19217391 22013068 16537920 16611888 18485870 9194565 12660246 9809062 23796514 11359905 12501250 15295102 19407812 25651062 23329847 16135789
GNAI1 SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23109003 11007482 10753828 9722546
GRK5 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 27326393 15053879 22223642 20124405 26029824 26226012
PRKCD NOS3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 17210830 24379783
SRC PRKCD â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 29.0 1.0 Omnipath 15851033 14970215 17569658 19366211 26876198 27203386 15961393 24211614 16982614 17570831 23329791 23329794 15541367 18550549 22689788 28637715 14715667 29422059 17658731 10319993 19138410 11927579 29452094 19632318 15337529
PRKCD TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 17906639 16314418 16377624
PRKCD TP73 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12097319 21188172
TP53 TP63 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 10606233 16931914 18388131 16516862 14576823 11382762 20442293 23019126 19858204 11238924 11423969
TP53 TP73 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11238924 18431400 21508668 9891077
TP53 TP63 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11238924 18431400 16713569