Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list

Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins

Filter Graph:

0.5
Layout:
  🔂

Click a node or edge for more data...

Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
SNCB APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SNCB SNCA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ADRB2 BSG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
ADRB2 SNCA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
AHSA1 HSP90AB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16696853 20618441
HSP90AB1 AIP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19375531 7021854
KCNIP3 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
GRK6 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PRKCD APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SNCA APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CCR2 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
HSP90AA1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CCR4 BSG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
CCR2 CACYBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
CANX MRPL16 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PPP5C CDC37 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8204010 21360678
CSE1L PPP5C â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
XPO1 DCAF8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22500989 8328086
POLR2E DYNC1H1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
FKBP4 FKBP5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 27462449 11751894
SERPINH1 FKBP5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
SMO FKBP8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
GRK6 PRSS23 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
GRK6 TYRO3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8939948 23331499
GRK6 SMO â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 15618519
HAX1 XPO1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23164465 8401898
KRAS PPP5C â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 Reactome 16892053 21779496
MC1R MRAP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0809918106 19329486
NRAS PPP5C â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 Reactome 16892053 21779496
RAB7A STUB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
STUB1 RCN2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
APP SNCA â—¼   PHYSICAL_INTERACTION 811.0 0.81 STRING 36370105
TNR1A GRK6 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
GRK6 NUCG â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
MANS1 GRK6 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CG031 GRK6 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
K226L GRK6 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CD83 GRK6 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RAB7A CDC42 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31536960 31871319
CDC42 VAPA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 26344197
DCAF8 XPO1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22500989 26673895
MRAP2 GRK6 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
NR4A1 GRK6 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
GRK6 NOLC1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
XPO1 NR4A1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26673895 22427340
GP183 GRK6 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
CDC37 FKBP5 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 25036637 24981860
CLPB HAX1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 32877691 31048321
PPP5C HSP90AA1 â—¼   PHYSICAL_INTERACTION ✅ 0.83 0.83 mint 27880917
AIP HSP90AA1 â—¼   PHYSICAL_INTERACTION 834.0 0.83 STRING 36370105
HSP90AA1 TTC4 â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
GRK6 RECO â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 16189514 16713569 12507501
AHSA1 FKBP4 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 25036637 22504172
KRAS NRAS â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
SUGT1 HS90B â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 18818696 16501598
GRK6 HS90B â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 19996089 22939624 32707033
FKBP5 HSP90AB1 â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
ADRB2 VAPA â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 24561123 28298427
VAPA FKBP8 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 32877691 26496610
PPP5C HSP90AB1 â—¼   PHYSICAL_INTERACTION ✅ 0.87 0.87 mint 27880917
PIH1D1 URI1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
POLR2E URI1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
RPAP3 URI1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
CDKAL1 MMS19 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
FKBP4 HS90B â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 28514442 25036637 21170051 21730179
MMS19 CIAO1 â—¼   PHYSICAL_INTERACTION ✅ 0.88 0.88 mint 8153045 21516116
ADRB2 SLC9A3R1 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
FKBP4 HSP90AA1 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
HSP90AA1 HSP90AB1 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
AIP HS90B â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 19375531 21170051 28634279 25036637
GRK6 ADRB2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 24561123 8672451 9819198
DCAF8 DDB1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 33288900 16964240 19966799 31391242 32235678 24500646 16949367 32703400 31257023 28514442 19295130 31155351
FKBP5 HS90B â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 25036637 21170051 30382094
SNCB SNCA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11683992 23630590
CCR5 CXCR4 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 12429730 18632580 15660419
NRAS CDC37 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 16024644 15118125 15284455
KRAS CDC37 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 16024644 15118125 15284455
PRKCD CXCR4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10521508 28449947
GRK6 LRP6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 19801552 20229235
NRAS HSP90AA1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 16024644 15118125 15284455
KRAS HSP90AA1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 16024644 15118125 15284455
HSP90AB1 NR4A1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
PRKCD MAPK8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17183360 16483929
PRKCD PRKDC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 19737086 9774685
HSP90AA1 RPAP3 â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
RPAP3 HS90B â—¼   PHYSICAL_INTERACTION 0.91 0.91 HIPPIE 17643375 24794838
FKBP5 HSP90AA1 â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
HSP90AA1 STUB1 â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
HSP90AB1 PPP5C â—¼   PHYSICAL_INTERACTION 919.0 0.91 STRING 36370105
HSP90AB1 PTGES3 â—¼   PHYSICAL_INTERACTION 946.0 0.94 STRING 36370105
HS90B AHSA1 â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 25036637 26344197 30382094 20226818 26693507 20618441 25486457
HS90B TTC4 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 25036637 18320024
AHSA1 HSP90AB1 â—¼   PHYSICAL_INTERACTION 962.0 0.96 STRING 36370105
CIAO1 MMS19 â—¼   PHYSICAL_INTERACTION 962.0 0.96 STRING 36370105
HSP90AA1 PPP5C â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
HSP90AB1 SUGT1 â—¼   PHYSICAL_INTERACTION 968.0 0.96 STRING 36370105
AHSA1 HSP90AA1 â—¼   PHYSICAL_INTERACTION 969.0 0.96 STRING 36370105
CDC37 HS90B â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 28215707 25036637 33961781 26496610 11036079 22939624 23428871 27339980 24189400 25486457
HSP90AA1 PTGES3 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
PIH1D1 RPAP3 â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
POLR2E POLR3A â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
HSP90AA1 SUGT1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
CDC37 HSP90AB1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CDC37 HSP90AA1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
SLC9A3R1 ADRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 11882663 15452121 9671706 10499588 9560162 11526121
PRKCD ADRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 11809767 11146000 1848190 8083204
GRK6 ADRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9819198 24561123
AHSA1 HSP90AA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 25036637 16696853 17145710 19875381 12604615 24462205 26693507 26804907 22315411 12504007 20226818 20159553 22504172
MAPK8 APP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 12917434 14970211 24610780 20122754 15936948
GRK4 BDKRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 11517230
PRKCD BDKRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 11517230
GRK6 BDKRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 11517230
PPP5C CDC37 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 21360678 18922470
CDC42 MAPK8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 25241761 12213839 25284480 18426980 10930450
CXCL12 CXCR4 â—¼   PHYSICAL_INTERACTION 11.0 1.0 ACSN 15261139 15882617 17035340 20535745 20644254 21521526 22025564 23034983 23402812 23567181 24277834
CXCL12 CXCR4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 41.0 1.0 Omnipath 24023874 10233851 10699158 11859124 22633458 18648536 18448868 8752280 30476826 12714578 16725153 9712844 8752281 9551924 21757744 19837984 25495026 26582643 16626895
CXCL12 CXCR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9660793
GRK6 CXCR4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 30936203 25355818 20048153 24309376 19116316 28328745 24489825
DNAJC7 HSP90AA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19875381 20661446 12853476 15189447
GRK6 LTB4R â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 20058876 22707565 30131369 12077128
GRK6 SLC9A3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 24.0 1.0 Omnipath 20166139 17895247 18088087 18452278 30696771 19413330 10446210 19664995 18669648 15302935
PTGES3 HSP90AA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 43.0 1.0 Omnipath 16565516 10642522 11447118 26804907 15916966 11413142 16403413 21988832 11812147 19875381 19740745 14761955 12077419 10811660 20039095 22806877 25036637 20048054 19996313 18285346 20661446 22315411 23022381 18172314 20159553 22729780 22504172 16289154 9817749 14987994 8114727
HSP90AA1 PPP5C â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10400612 16531226 21360678 15577939 15383005
PRKDC MAPK8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11749722 16319174
MAPK8 NR4A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 22002310 17023523
PPP5C PRKDC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 14734805
PRKCD TBXA2R â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 16956790 11516166 9054415 9915793 7961988 11015313 17466390 9560198 15100160 14530262
PTGES3 STUB1 â—¼   PHYSICAL_INTERACTION 20.0 1.0 ACSN 10197982 10995457 11283614 17055429 17327415 18566586 19387550 19662498 20027199 20093776 20713526 20959453 2191300 21945180 22032831 22869732 23430059 23551398 25103413 25487024
PTGES3 STUB1 â—¼   SHARES_COMPLEX 20.0 1.0 ACSN 10197982 10995457 11283614 17055429 17327415 18566586 19387550 19662498 20027199 20093776 20713526 20959453 2191300 21945180 22032831 22869732 23430059 23551398 25103413 25487024
PRKDC PRKDC â—¼   KO_DOWN_REGULATES ✅ - -4.22 4.21 PKG 28854368