Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
ARAF YWHAG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
ATP2A2 TNFRSF1B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
ATP2A2 TNFRSF1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HTT CASP3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CASP9 CASP3 â—¼   CLEAVAGE ✅ 2.0 0.8 intact 0707715105 18723680
CASP3 AKT1 â—¼   CLEAVAGE ✅ 2.0 0.8 intact 17544405 5219985
CASP3 CASP9 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 12011067 15573119
HTT CASP3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16777606 10770929
XIAP CASP9 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11242052 5213680
XIAP CASP9 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
HSP90AA1 AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12799359 11988487
STAT5B HSP90AA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19014541 22552610
HTRA2 EIF3F â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
IL1A IRAK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8599092 9430229
HAX1 KAT5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
KAT5 SYN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
KAT5 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
KAT5 PELO â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HAX1 TNFRSF1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
SLC25A5 TNFRSF1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
AIFM1 TNFRSF1B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
XPO1 TNFRSF1B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HAX1 TNFRSF1B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
SLC25A5 TNFRSF1B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HAX1 EIF3F â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
HAX1 DCP1A â—¼   COLOCALIZATION 2.0 0.8 intact 23164465 8401898
YWHAG RAF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11697890 8005785
RAF1 AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19197339 7014125
CUL3 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
GZMB HAX1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20388708
IGF1R YWHAG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
HTT AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
AIFM1 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
YWHAG TUBA1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
TUBA1A MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TUBA1A HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
YWHAG HAX1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
YWHAG MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
YWHAG PELO â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
STAT5B INSR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 9428692 6730856
STAT5B INSR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10830280 15055356
PELO HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
VDAC2 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
GPM6A HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PHB2 PHB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
DUSP16 MAPK10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15888437 11359773
HAX1 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
SLC25A5 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
GRK6 TYRO3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8939948 23331499
HAX1 XPO1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23164465 8401898
HAX1 DGKD â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
PRNP NCAM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16713569 15146195
COX4I1 VDAC2 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
AKT1 XIAP â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 23640046 25241761 14645242 33631302
PHB2 VDAC2 â—¼   PHYSICAL_INTERACTION 809.0 0.81 STRING 36370105
CFTR YWHAG â—¼   PHYSICAL_INTERACTION 810.0 0.81 STRING 36370105
LATS2 SAV1 â—¼   PHYSICAL_INTERACTION 811.0 0.81 STRING 36370105
ABCE1 HAX1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 25659154 32877691
ARAF HAX1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 32877691 29777862
ARAF AIFM1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 29777862 25852190
XIAP CASP3 â—¼   PHYSICAL_INTERACTION ✅ 0.82 0.82 mint 9525868 6547707
HTRA2 LATS1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17130845 22641346 16007220
ESR1 PSMD2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19805454 25604459
CUL3 PSMD2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 22466964
RIPK4 RBX1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 29435596 26972000
RBX1 HAX1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30349055 21988832
IGF1R ERBB2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17307140 30898150
CFTR AIFM1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26618866 17110338
AIFM1 SFXN1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 27218139
CFTR HAX1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26618866 17110338
HAX1 GRIA2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
PHB2 SFXN1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31536960 34079125
SVIL ESR1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33731348 11792840
HAX1 E41L1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
HAX1 AKA10 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 20171186 21715506
TAU GPM6A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33961781 26402096
HAX1 SCAM1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
HAX1 MARE3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
HAX1 GNAO â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
HAX1 DPP6 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
HAX1 KAP3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
HAX1 CALB2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
LACTB DJC11 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31536960 31617661
PHB2 XIAP â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
XIAP AIFM1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 17967870 22103349
HAX1 NCALD â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
ESR1 EIF3F â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 30573685 19805454 31527615
HAX1 HPCA â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
HAX1 APOD â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
HAX1 STX1B â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
HAX1 STX1A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
HAX1 DCX â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
HAX1 MLF1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 32877691 33961781 25036637
KAP3 MAP2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
HAX1 MAP2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
HAX1 SYT1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
HAX1 DNM1L â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
HAX1 ANK2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
HAX1 CNTN1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
HAX1 DCLK1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
HAX1 L1CAM â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
HAX1 SYN1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
HAX1 DYN1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
HAX1 DPYL1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
HAX1 EDIL3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
HAX1 DPYL5 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
HAX1 SYN2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
HAX1 STXB1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
HAX1 LASP1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
HAX1 TAU â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
HAX1 KCC2A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
CLPB HAX1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 33961781 32877691 31048321
HAX1 RAB6B â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
HAX1 GBG2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
HAX1 KCC2B â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
GPM6A HAX1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
HAX1 GPDM â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
HAX1 SNAB â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
HAX1 CAMKV â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
HAX1 DPYL3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
HAX1 AP180 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
HAX1 VISL1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
HAX1 NCAM1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
HAX1 NTRI â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
HAX1 ATP4A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
HAX1 HPCL1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
HAX1 DPYL2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
HAX1 NDRG4 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
HAX1 H2B1L â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
CHEK1 CUL4A â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
BECN1 ERBB2 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 28205554 23703612 28628118 28351972
ESR1 IGF1R â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 10749889 24051437 14764897 28555617 16113100
AIFM1 HAX1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 34079125 29568061
AIFM1 DJC11 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 34079125 29568061
AIFM1 CLPB â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 34079125 29568061
CFTR SVIL â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 29924966 17110338
ATP2A2 PLN â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
ABCE1 EIF3F â—¼   PHYSICAL_INTERACTION 844.0 0.84 STRING 36370105
CASP9 CASP3 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 11242052 8900201 25241761 1067155 15941357 11230124 15507451 18723680 17437405
BECN1 XPO1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 26673895 16713569 11309306
ILK HAX1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 32707033 23455922 25852190
CFTR XPO1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 26618866 29924966 17110338
DCX DCLK1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 28514442 32707033 33961781 26186194
LATS2 LATS1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 33961781 24255178 34079125 32707033 21233212
IGF1R INSR â—¼   PHYSICAL_INTERACTION 854.0 0.85 STRING 36370105
HTRA2 HAX1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 31617661 17906618
CUL4A SFXN1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 34079125 21145461
ILK AIFM1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 23455922 25852190
AKT1 TAU â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 19014373 17512525 18292230 31358653
ESR1 DNM1L â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 19805454 21217774
MK10 HAX1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 23602568 21988832
SYN2 SYN1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 10358015
TAU MARE3 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 34079125 30668577
RAF1 XIAP â—¼   PHYSICAL_INTERACTION 860.0 0.86 STRING 36370105
ARAF RAF1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 31980649 34017080 20130576
BIRC3 CASP3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 17069460 9384571
TAU PSMD2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 26269332 32357304
ILK RAF1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 23455922 26496610 25852190
SAV1 HAX1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 22570112 21567072
TAU MAP2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 8990203 26269332
ESR1 PHB2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 10938099 24051437 12943695 26052702 17932104 19805454 28555617 10359819 15140878
DPYL1 DPYL3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 32296183 25416956 33961781
DJC11 HAX1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 33957083 32877691 26496610
CASP3 CASP9 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
ESR1 PHB2 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
ERBB2 GRB7 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
DCLK1 DCX â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
MLF2 AIFM1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 17353931 29568061
CFTR PSMD2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 31324722 29924966 17110338
BECN1 AKT1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 29669822 23112296 28628118 28205554
ILK AKT1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16189514 12149249 9736715 12176337 11445557 18339839 11825911 11313365 14500673 11278835 11546794
CFTR STX1A â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 9384384 12209004
DPYL5 DPYL3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 10956643 32296183 33961781
DPYL5 DPYL2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 32296183 25416956 29892012 10956643 33961781
AKT1 RAF1 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
ESR1 HSP90AA1 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
HTRA2 BIRC3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11583623 12865429 30948266
RAF1 XIAP â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16964381 25241761 19011619
RAF1 YWHAG â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
SAV1 LATS2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 25670202 34404733 25692647 24255178 30266805
DPYL1 DPYL2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 21900206 32296183 12482610 24722188
DPYL2 DPYL3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 29892012 25416956 32296183 33961781
BIRC3 CASP9 â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
YWHAG ARAF â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 5217174 15324660
CASP3 XIAP â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 16189514 25241761 11447297 9525868 11257230 19698783 9384571 22815893 15507451 16869888 17291493 15200957 27927753 19273858 18723680 16543147 23074197 11927604 18521960 30522111 23979166 17069460 12624662 15650747 11257232 11359776 33961781 26186194 22072751 9230442
CASP9 XIAP â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16189514 25416956 25241761 19698783 9545235 15507451 11801603 17291493 19153467 11242052 32296183 15280366 15749826 31467278 16701639 17179183 15300255 23074197 11390657 11927604 18022362 27107012 30522111 14512414 12620238 29997244 25502805 14523016 15069192 16322207
CASP9 BIRC3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16701639 25241761 21988832 16339151 9545235 15069192
HTRA2 XIAP â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16189514 15781261 15201285 16713569 15300255 31470122 28642151 17906618 24698088 11604410 29631059 31617661 12865429 11583623 11606597 11602612 11803371 11801603
HTRA2 HAX1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 11803371 15371414 23070005
AKT1 HTRA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17311912
HAX1 IL1A â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16189514 16971486 11554782 25416956
RPA1 KAT5 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18171670 11080452 17965729
ESR1 KAT5 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 31527615 17418098 16260778 22081016 11591700
RBX1 CUL4A â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17079684 16189514 15448697 10230407 12481031 17452440 22474075 11861641 18593899 30349055 19295130 22405651 33759138 30352932 27113764 26976604 27203177 26990986 19250909 27203182 31973889 32235678 29958295 22863883 33961781 33504946 19287380 30945288 32140073
PRKACG PLN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 25278000 10198180 26347652
AKT1 PLN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18838385 19696029
AKT1 RAF1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16189514 25241761 28628118 10576742 19197339 19058874 28205554
TNK2 AKT1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 10652228 11394904 18470881
MAPK6 TUBA1A â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
SYT1 STX1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9010211 11438523
GRB7 ERBB2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 22973453 9079677 12975581 7907978 17875712 16273093 12061724
STAT5B ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11731618 11682625
MAPK6 CNTN1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
MAP2K7 MAPK10 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 16186825 9162092 17875933
NCAM1 L1CAM â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 8509458 10611478 2295682
ERBB2 HSP90AA1 â—¼   PHYSICAL_INTERACTION 908.0 0.9 STRING 36370105
HTRA2 XIAP â—¼   PHYSICAL_INTERACTION 911.0 0.91 STRING 36370105
STX1A SYT1 â—¼   PROTEIN_INTERACTION 0.93 0.93 HIPPIE 11438523 9010211 10397765
XIAP CASP3 â—¼   UBIQUITINATION ✅ - 0.94 0.94 Signor 11447297
HSP90AA1 RAF1 â—¼   PHYSICAL_INTERACTION 942.0 0.94 STRING 36370105
AKT1 HSP90AA1 â—¼   PHYSICAL_INTERACTION 946.0 0.94 STRING 36370105
CUL3 RBX1 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 19818716 15448697 12481031 11861641 30349055 25270598 20027226 22405651 26100637 19256485 11311237 19250909 25278611 26286618 20865015 15601839 19617556 29958295 33504946 12684064 24145166
STXB1 STX1B â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 12093152 31413325
STX1A SYT1 â—¼   PHYSICAL_INTERACTION 955.0 0.95 STRING 36370105
XIAP HTRA2 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 24698088
HTRA2 XIAP â—¼   PROXIMITY ✅ 0.96 0.96 mint 31617661
KCC2A KCC2B â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 32296183 17353931 33961781 27173435 29426014 32707033
CASP3 XIAP â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
CASP9 XIAP â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
CUL4A RBX1 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
CUL3 RBX1 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
YWHAG ARAF â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 17145710 17353931 15324660
PLN ATP2A2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 11854448 10809745 11526231 16189514 12838339
BIRC3 CASP3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 9990849 12042762 9384571 17069460
GZMB CASP3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 19254476 17179148 19103589 17283187 16495481 8700869 9694885 12745270 15569669 9233763 16415351 8755496 11696597
CASP9 CASP3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 37.0 1.0 Omnipath 10708865 9390557 10508159 11230124 18723680 15657060 16977332 15507451 1067155 9708736 25241761 8900201 11242052 9765224 17437405 19788417 9812896 12620238 15941357 12181739 19465923 12792650 15725726
XIAP CASP3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 70.0 1.0 Omnipath 23074197 16543147 22072751 12624662 18521960 22815893 11157976 15650747 15200957 11927604 11230124 9384571 16869888 9545235 23979166 18723680 16189514 11359776 15507451 9230442 19273858 26186194 10508158 25241761 12529384 19559631 11257230 12874265 9525868 17291493 11583623 11257232 17069460 12181739 10548111 11447297 15014070 19698783
CASP3 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 17544405 12124386 10579725
AKT1 CASP9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 42.0 1.0 Omnipath 11756412 11923280 16697215 20398329 18372248 15004527 15808505 20138985 20214616 15703181 17570479 28177918 18840507 15169778 11714830 10949026 16341064 11715018 18636226 10529400 9812896 17680028 19440551 10722653 20832730 18570873 17052453
GZMB CASP9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 1067155 8900201 16189514 9651578
BIRC3 CASP9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 16339151 21988832 9990849 15069192 25241761 9545235 16701639
XIAP CASP9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 62.0 1.0 Omnipath 15069192 15280366 25416956 18022362 11157976 31467278 15200957 11927604 11230124 12042762 16322207 9545235 11801603 25502805 14512414 16189514 15300255 15507451 10508158 25241761 27107012 14523016 17179183 16352606 11242052 32296183 16701639 17291493 12620238 15749826 12181739 11390657 29997244 31515488 23074197 19698783
CHEK1 RPA1 â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
CHEK1 RPA1 â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
CHEK1 RPA1 â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
AKT1 CHEK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 21.0 1.0 Omnipath 20832017 18691976 23108403 17418864 20068231 12062056 15107605 17570479 19664995 18669648 26091525
HSP90AA1 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 19356729 18266962 10995457 25714412 16189514 12176997 12586360 15843522
HSP90AA1 RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 25036637 19011619 16093354 8962087 18266962 8408024 23118896 22939624 24462205 16189514 17699868 20039095 16504566 20159553 17409432 16330544 15618521
HTRA2 XIAP â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 ACSN 10521396 11583623 11803371 12815069 12835328 15781261 19935698 20125124 23070005
HTRA2 BIRC3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 11606597 12865429 11583623
HTRA2 XIAP â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 45.0 1.0 Omnipath 12835328 11606597 16713569 12815069 28642151 17311912 15200957 17906618 11803371 29631059 12865429 11801603 15201285 15300255 11604410 11583623 11602612 15781261 24698088 31470122
RPA1 RBX1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
RBX1 CUL4A â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 11900249 12648680 12820959 15071497 15340381 15459660 15688063 1570337 15703371 16697054 17884153 18931676 19270156 19557001 19622404 19686080 19809470 19847258 20211143
RBX1 CUL3 â—¼   PHYSICAL_INTERACTION 34.0 1.0 ACSN 11583996 11900249 12648680 12820959 14744430 15340381 15459660 15688063 15703371 15760909 16498403 16547521 16697054 17312394 17884153 18545270 18931676 19090789 19427028 19560419 19622404 19686080 19809470 19818716 19847258 20006983 20531300 20599425 23030059 23377657 23845861 23850759 27984721 9242610
RBX1 CUL3 â—¼   SHARES_COMPLEX 34.0 1.0 ACSN 11583996 11900249 12648680 12820959 14744430 15340381 15459660 15688063 15703371 15760909 16498403 16547521 16697054 17312394 17884153 18545270 18931676 19090789 19427028 19560419 19622404 19686080 19809470 19818716 19847258 20006983 20531300 20599425 23030059 23377657 23845861 23850759 27984721 9242610
RBX1 CUL4A â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 11900249 12648680 12820959 15071497 15340381 15459660 15688063 1570337 15703371 16697054 17884153 18931676 19270156 19557001 19622404 19686080 19809470 19847258 20211143
AKT1 RBX1 â—¼   ENZYMATIC_REACTION ✅ 45.0 1.0 ACSN 10722653 10949026 11274345 11715018 11756412 11756498 11923280 12408816 12906785 15169778 15808505 16469695 16697215 17052453 17461779 17680028 18000759 18372248 18492954 18570873 18636226 18925875 19022819 19143635 19151919 19568798 19720745 20027184 20138985 20214616 20338997 20398329 20832730 21157483 21474067 21981924 23087689 24795729 24973821 25002027 25730849 26159692 27331412 28216025 9812896
AKT1 RBX1 â—¼   DOWN_REGULATES ✅ - 45.0 1.0 ACSN 10722653 10949026 11274345 11715018 11756412 11756498 11923280 12408816 12906785 15169778 15808505 16469695 16697215 17052453 17461779 17680028 18000759 18372248 18492954 18570873 18636226 18925875 19022819 19143635 19151919 19568798 19720745 20027184 20138985 20214616 20338997 20398329 20832730 21157483 21474067 21981924 23087689 24795729 24973821 25002027 25730849 26159692 27331412 28216025 9812896
RPA1 CUL4A â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
TNFRSF1A BIRC3 â—¼   PHYSICAL_INTERACTION 11.0 1.0 Reactome 35941131 22179575 22848449 23313255 24098568 34876703 16282325 20385093 22435550 18178551 19910467
TNFRSF1A MAP2K7 â—¼   ENZYMATIC_REACTION ✅ 22.0 1.0 ACSN 11274345 12556535 12655147 12738796 14730360 15592525 17462996 18641653 18855897 19392652 19524513 19632174 21133840 21232017 21614932 23010170 23850759 24378531 26587781 26653790 28574505 28765050
TNFRSF1A MAP2K7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12655147 21614932 12738796 11274345 18855897
TNFRSF1B BIRC3 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 7639698 25152365 19815541 8702708 7544915
TNFRSF1B MAP2K7 â—¼   ENZYMATIC_REACTION ✅ 14.0 1.0 ACSN 11274345 12556535 12655147 12738796 15592525 17462996 18641653 18855897 19392652 21133840 21232017 21614932 23850759 24378531
RAF1 XIAP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16964381 19011619 25241761
AKT1 XIAP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 23640046 25241761 17698078 14645242
AKT1 RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 51.0 1.0 Omnipath 19197339 11971957 18767875 20230923 10576742 20068231 17570479 16189514 18669648 25241761 18691976 10576741 10618391 20688159 21745501 12087097 12801936 12048182 22798428 16854453 19058874 11997508
RAF1 YWHAG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 17353931 11697890 8702721 10433554 16189514 15664191
ILK AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 35.0 1.0 Omnipath 11546794 14500673 12176337 11445557 15899889 23840605 9736715 12149249 10592173 11313365 16189514 19460343 11278835 15212693 18772455 10226025 11825911
ESR1 IGF1R â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 17170218 20021813 16087727 19250214 10982795 24281069 18414489 15595626
IGF1R YWHAG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 12767520 10826997 12444011 21540285 17145710 17353931 19030972 16931767 15324660 12175651
ESR1 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11029009 15569929 18450422 20664923 15496458
TNK2 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 22322295 11394904 25678401 20333297 10652228
AKT1 IRAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 11976320
AKT1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 18521086 26944939 11108261 17627277 20101208 17570479 15604293 23169992 26554417 16452229 15193262 7838153 12374744 11139588 26272591 11432835 20179234 11507039 9528769
AKT1 YWHAG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 20138985 15169778 9812896 17680028 11756412 11923280 20214616 16697215 10949026 10722653 20832730 18570873 18372248 11715018 20398329 17052453 18636226 15808505
AKT1 PHB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 24522204 21689744 15173318
STXB1 STX1A â—¼   PROTEIN_INTERACTION 1.0 1.0 HIPPIE 12093152 7553862 15563604 10746715 10194441 10449403 17363971 7768895 31413325 8108429 12963086 9045631 12519779
LATS2 YWHAG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 21118956 25086053
INSR GRB7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23331499 10803466
PHB2 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 15140878 17932104 26052702 10938099 12943695
ESR1 ERBB2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 24559156 16115928 16467118 17992604 19915977 15199112 21127199 21761336 21907803 20551150 11713584 1358436 20629094 18768663 19005469 9242384 20889718 10698518 16467117
ERBB2 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23331499 15173068
MAP3K3 MAP2K7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12738796 18855897 11274345 21614932
PPP3CC DNM1L â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18838687 17721437
MAP2K7 MAPK10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 29.0 1.0 Omnipath 11489946 9362518 18855897 18083107 10715136 23331499 9890973 11062067 21614932 15911620 12738796 11389443 11242024 12624093 11847100 18691976 16076903 14523011 15212693 11274345