Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
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Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
PAX8 NCAM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8071351
BARX2 L1CAM â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15034005 9122247
BARX2 NCAM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15034005 10781615
KIF4A KIF4B â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10747093 10804209
SRC ACTB â—¼   COLOCALIZATION 2.0 0.8 intact 7296071 19903481
SH3GL2 ACTG1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
CTNNB1 AHR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19651607 0902132106
AHR L1CAM â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17903170 17707923
AP2S1 AP2A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15749704 15911768
AP2A2 AP2A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15749704 15911768
AP2M1 AP2A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15749704 15911768
AP2B1 AP2A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15749704 15911768
AP2A1 MAPK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10608864 10818153
AP2A2 AP2A1 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15749704 15911768
AP2B1 AP2A1 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15749704 15911768
AP2S1 AP2A1 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15749704 15911768
AP2M1 AP2A1 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15749704 15911768
AP2B1 AP2A2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15749704 15911768
AP2M1 AP2A2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15749704 15911768
AP2S1 AP2A2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15749704 15911768
AP2A2 MAPK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10608864 10818153
AP2M1 AP2A2 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15749704 15911768
AP2B1 AP2A2 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15749704 15911768
AP2S1 AP2A2 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15749704 15911768
MAPK1 AP2B1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10608864 10818153
AP2M1 AP2B1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15749704 15911768
AP2S1 AP2B1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15749704 15911768
AP2M1 AP2B1 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15749704 15911768
AP2S1 AP2B1 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15749704 15911768
AP2S1 AP2M1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15749704 15911768
MAPK1 AP2M1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10608864 10818153
AP2S1 AP2M1 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15749704 15911768
MAPK1 AP2S1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10608864 10818153
APBB1 ERBB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218056 16273093
CLTA MAPK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10608864 10818153
MAPK1 CLTC â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10608864 10818153
L1CAM CSNK2A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17253643 8592152
CSNK2A1 CSNK2B â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
CSNK2A2 L1CAM â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17253643 8592152
L1CAM CSNK2B â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17253643 8592152
CTNNB1 EPHB3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12408869 12782598
SP1 DPYSL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15207709
SP1 EPHB2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9918860 10751319
SRC ERBB3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218056 16273093
ERBB3 FGFR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218056 16273093
TFAP2A ERBB3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18358466 11278550
FLI1 EWSR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16206264 10975680
EWSR1 FLI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16206264 10975680
SP1 EZR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19164283
HR L1CAM â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17903170 21150308
ITGA5 NRP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19175293 1000025
NFIC ITGA5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18775869
ITGB3 ITGAV â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5214491 11546839
PEA15 L1CAM â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
MAPK1 L1CAM â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10608864 10818153
TFAP2A L1CAM â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12077189
REST L1CAM â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20003413 9298989
MAPK1 L1CAM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17151951 21080252
L1CAM PLXNA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10520994 15121181
SP1 LAMC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12034813 9403717
SP1 MAP2K1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17889508 16452190
MAPK1 MAP2K1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 23241949 8412360
SRC MAPK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16580177 9924018
MAPK1 SH3GL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10608864 10818153
MAPK1 RPS6KA2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12832467 16626623
MAPK1 RPS6KA1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12832467 16626623
RPS6KA1 MAPK1 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
PRNP NCAM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16713569 15146195
NFIC TGFB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15047811 8939900
SP1 PRNP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19064990
SRC SP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ITGA5 ITGB3 â—¼   PHYSICAL_INTERACTION 818.0 0.81 STRING 36370105
AP2A1 AP2S1 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
L1CAM PRIO â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29791485 15146195
KTU NCAM1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
EGFR ACTB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22366308 31980649
NUMB AP2B1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 23211419 34079125
EGFR CNTN2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31980649 20029029
DGUOK NCAM1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
NUMB EGFR â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 16273093 25754235
TGFB1 LAMB1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 20936779 27684187
AP2A1 AP2B1 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
NUFP1 NCAM1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
NUFP1 L1CAM â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
NUFP1 CNTN1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
NUFP1 ANK2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
KTU ANK2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
KTU L1CAM â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
KTU CNTN1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
HAX1 ANK2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
DGUOK ANK2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
EGFR AP2S1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 24189400 25754235 24797263
DGUOK CNTN1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
HAX1 CNTN1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
DGUOK L1CAM â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
HAX1 NCAM1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
HAX1 L1CAM â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
TGFB1 LAMC1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
AP2B1 CLTC â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
EZRI ERBB2 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 27029001 24658140
FGFR1 NCAM1 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
WRN PEA15 â—¼   KO_DOWN_REGULATES ✅ - -0.85 0.84 PKG 28854368
EGFR EZRI â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 24658140 1382070 31980649 12560083
SPTA1 ANK1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 2971657 15929114
EGFR AP2A2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 31959764 24797263 23956138 8548289 24189400
EGFR AP2B1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 24189400 24797263 23956138 7534311
NCAN L1CAM â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 10934197 7513709
AP2B1 AP2M1 â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
AP2A1 NUMB â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
AP2A1 AP2M1 â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
AP2B1 AP2S1 â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
LAMC1 LAMB1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 17517882
WRN L1CAM â—¼   KO_DOWN_REGULATES ✅ - -0.88 0.87 PKG 28854368
EGFR SH3GL2 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
EGFR AP2A1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 31959764 24797263 23956138 25754235 20029029 24189400 7534311
AP2M1 AP2S1 â—¼   CORRELATES + 0.88 0.88 CCLE 31978347
PEA15 MAPK1 â—¼   DOWN_REGULATES ✅ - 0.88 0.88 Signor 11702783
CSNK2A1 CSNK2A2 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
AP2A1 AP2B1 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
EGFR AP2M1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 31959764 24797263 31980649 24067654 23956138 25754235 20029029 24189400
AP2M1 NUMB â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 26186194 28514442 24189400 23211419
ERBB2 SRC â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
PAX8 L1CAM â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21097529
ANK1 ACTB â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16904324 11222639 17223356
L1CAM ACTB â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16904324 11222639 17223356
ACTB ANK2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16904324 11222639 17223356
EZR ACTB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16189514 7876308
ANK1 ACTG1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16904324 11222639 17223356
L1CAM ACTG1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16904324 11222639 17223356
ACTG1 ANK2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16904324 11222639 17223356
ANK1 SPTAN1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16904324 11222639 17223356
SPTA1 ANK2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16904324 11222639 17223356
NUMB AP2A1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 17203073 23211419 12942088
SP1 CD9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8760289
SP1 CSNK2A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10849443 19027835
MAPK1 CSNK2A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19941816
CSNK2B DNMT1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
ERBB3 EGFR â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 23436906 10527633 27756321 21278786 18803307 17148612 22439932 25315821 10572067 24189400 23866081
SRC ERBB2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 22973453 19704002 21075308 7542762 7797556 19372587 29720121 11940572 17875712
SOX10 ERBB3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11156606 11799060 21672228
TFAP2A FGFR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 2822255 19699737 20046871
SPTA1 L1CAM â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16904324 11222639 17223356
NCAM1 L1CAM â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 8509458 10611478 2295682
L1CAM SPTAN1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16904324 11222639 17223356
L1CAM NRP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16377081 10520994 15121181
MAPK1 MAP2K1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 10567369 19219045 8013650
NRP1 PLXNA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10520994 15121181
SP1 SRC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10625617 19112177
ACTB ACTG1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
MAPK1 RPS6KA2 â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
ERBB2 ERBB3 â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
CSNK2A2 CSNK2B â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
HOXA1 TGFB1 â—¼   PHYSICAL_INTERACTION 0.92 0.92 HuRI 32296183
EGFR SRC â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
L1CAM EZRI â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 22846990 12070130
MAPK1 PEA15 â—¼   PHYSICAL_INTERACTION 949.0 0.94 STRING 36370105
PRIO NCAM1 â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 29791485 27535221 15146195
ACTG1 ACTB â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 8153045 21516116
ERBB2 EGFR â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 5218411 16516204
KIF4A KIF4B â—¼   CORRELATES + 0.95 0.95 CCLE 31978347
EPHB2 SRC â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 18713744 9632142 10644995
ITGAV TGFB1 â—¼   PHYSICAL_INTERACTION 963.0 0.96 STRING 36370105
AP2A1 AP2M1 â—¼   PHYSICAL_INTERACTION 969.0 0.96 STRING 36370105
SRC EGFR â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 22227249 17284441 24658140 17158602 21278788 20333651 28065597 7527393 7797556 10777553 16713569 20624308 23175185 7506422 22973453 20935677 24189400 11983694 10075741 31980649 19704002 10358079 10971656 21268077 9020193 25402006 21573184 8845374
ERBB3 ERBB2 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 22806884 25898135 30523157 9130710 21278786 15812817 20227043 16843263 10572067 19411071 19060928 8665853 10799311 8816440 17426253 17148612 21075308 12896906 15504738 23680147 23688700 23866081 22733765 7592681 21203579 25326665 24557338 23436906 30898150 7538656 25241761 25315821 11173924
AP2A1 AP2S1 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
LAMB1 LAMC1 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
EGFR ERBB3 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
MAP2K1 MAPK1 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
AHR ARNT â—¼   PHYSICAL_INTERACTION 979.0 0.97 STRING 36370105
CSNK2B CSNK2A1 â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 36833176
AP2A2 AP2B1 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
MAPK1 RPS6KA1 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
EGFR ERBB2 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
CLTA CLTC â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
ARNT AHR â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 10619402 33961781 7628454 11768231 19390533 22138065 10395741 26350169 20006590 10617682 31675361 11259609 23477502 17392787 12139968 9887096 8631989 28514442 9704006 8065341 18096572 8621524 7488247 8619634 11025203 10671489 11551916 8384309 12024042 19380484
AP2B1 AP2S1 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
AP2A2 AP2M1 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
AP2B1 AP2M1 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
AP2A2 AP2S1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
AP2M1 AP2S1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CSNK2A1 CSNK2B â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
SP1 AHR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 9778040 16410262 21569840 20478378
ARNT AHR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 29.0 1.0 Omnipath 17145710 8621524 8384309 9887096 20006590 10395741 18096572 12024042 7628454 9704006 19380484 17823304 11259609 19390533 22138065 8631989 8619634 8065341 11768231 7488247
SRC AP2B1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 18938240 15592455 17456551 18083107
AP2M1 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 23956138 31980649 24189400 19351721 20029029 24797263
MAPK1 APBB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 14697653
CSNK2A1 ARNT â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 16129408 18669648
SP1 BSG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 22678117 20629990 21470566 20384626 24906624 11814679
SRC CLTC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 10089883 19289168 12237126
COL4A1 ITGAV â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 14610079
CSNK2A2 CSNK2A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 26186194 27705803 25519132 19011756 26496610 25852190 23455922
CSNK2A1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 12700239 12432063
CSNK2A1 TFAP2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 21777522
CSNK2A1 SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 9153193
CSNK2A2 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12700239 19141652 12432063
CSNK2B CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 12432063
FGFR1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 17496910 25241761 22558232 11401320 12040186 19568798 14585353
ERBB2 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 17496910 7702605 7999105 22558232 14517306 11245482 11950845 12040186 19568798 23576562 14585353 23640056
SRC CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 46.0 1.0 Omnipath 22605996 16492141 27177845 23824743 25423132 25850673 24816560 27203386 11836526 22515442 26918136 10593980 15782139 9592087 22056988 12571228 17087658 20840866 23640056 21195420 25164010 26453937 9278444 16831887 23476652 12123611 11279024 14517306 21903109 22200182 20026641 22264731 25041845 12408824 22247700
EGFR CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 32.0 1.0 Omnipath 19104148 27401557 15371335 16099633 22558232 30747223 12040186 26509276 24816560 12740122 25500543 17318191 19568798 21423209 14585353 34227224 23640056 17496910 17052462 24240237 25164010 14517306 21903109 22200182 16952352 20858269 28035485 9233779
CTNNB1 SNAI2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 20731704 19751508 7542250 11967263 22406545 17093497 21317430 11955436 22270359 18832382 12051714 8666229 12490555 16510505 16940750 21199805 17550342 16831886 14623871
DNMT1 FGFR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17172825 18704159 21779870 21150308
SP1 EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 1282800 17616668 18575762 19538880 15665278 18202149 20435036 21705183 18007664 21464950 23821666 15533438 9819401 10830317 8393457 16087726 20407012 18391986
TFAP2A EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16449191 8621697 14522076
MAPK1 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 12556561 1651322 17081983 3138233 15901825 1939237 91332050 2543683 2115882 17192257 1651323 15302935
SRC EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 232.0 1.0 Omnipath 16414009 17081983 25958313 16943190 15618223 19935697 19305428 25402006 24797263 29285309 7488034 15592458 17389395 16461772 20562096 19275932 17897439 15899872 17570479 2803273 23636329 23246962 25505586 23175185 15615697 23349873 16849545 25356505 11983694 24189400 11756413 25748412 26325669 26150526 14512423 18789131 14750954 31978707 25573954 27495374 20071362 18707149 28759036 16729043 26494466 27716204 25537504 17237269 18687633 25884760 29036202 26936397 17575160 20926745 20935677 15282306 23702846 15476828 9069259 19336574 20421302 15660394 23866081 19377510 9777370 22426783 29321659 33706413 25841779 19840943 18669648 12397069 16843263 18957516 34088769 25077442 14963038 19836242 17653080 19625610 16936701 11960379 15548697 18295415 17523611 21268077 20333651 21399647 23376850 11250711 23942551 19704002 22927910 11160627 31952541 10777553 17016520 2543678 19258037 33883672 17646646 28102297 23873690 26771606 21573184 23119029 19151764 16713569 7797556 25955608 15302935 20407013 28513565 23119185 9990038 21080693 20190765 25347738 14630916 15708852 21822308 20628053 25301722 24658140 19690143 27564112 20802523 29124875 33657368 12101233 21787862 14764607 17284441 12878163 26290602 15951569 16543144 15212693 17971399 14523024 10971656 21278788 8845374 22430206 18083107 29641465 18234969 18460189 17551925 22957061 26571308 17043637 20371672 10358079 16799092 19154417 23066441 28065597 12842895 18180459 17158602 18271526 15657067 25159151 34367939 24919575 10075741 25366117 24349301 17561374 16862179 20215522 31980649 24335899 16037379 18451158 14530278 16505275 12063263 23449029 11311660
TGFB1 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20953304 32103204 19132220 28943431
EGFR ERBB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 65.0 1.0 Omnipath 17081983 16207817 21044682 17148612 24557338 16713569 21203579 10233167 20471394 17389395 17486068 21278786 11500516 11279155 11500850 17426253 16843263 19650109 25241761 24189400 15657067 17307140 18803307 1706616 12354693 10572067 24355130 11408594 19060928 12648464 16516204 15951569 23436906 20211985
EGFR MAP2K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12556561 15531749
EGFR ERBB3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 17145710 23436906 7929151 21278786 24189400 23866081 17148612 12648464 27756321 18803307 10527633 10572067 22439932
EGFR EZR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 1382070 31980649 24658140 12560083 9230083 15212693 10377409 15647376
EPHB2 SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 18713744 10644995 9632142
TFAP2A ERBB2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 19906305 10645007 7846046 22577344 18177484 15870067 9850080 10698518 16108032 11485026 18218085 12942124
ERBB2 ERBB3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 44.0 1.0 Omnipath 17145710 23680147 17148612 24557338 19411071 21203579 7592681 23688700 23331499 21278786 12648465 22806884 27531070 17570479 30898150 29066975 17426253 16843263 9130710 20227043 25241761 10799311 8816440 22733765 10572067 19060928 11173924 21075308 23436906 7538656 15504738
ERBB2 SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16769082 19617202 11940572 12753909 21075308 7542762
SP1 EZR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21628504 19164283
SRC EZR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 16438931 22397367 14504278 25231728 21818323 24339867 15623525 18701134 22262457 24385580 18078820 28306714 15647376
L1CAM EZR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22846990 12070130
FGFR1 MAPK1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 19652666 12419216 18452557 12974390
MAPK1 FGFR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 27342992 23405013
NCAM1 FGFR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 18593816 12121226 12791257
SP1 ITGA5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 22227038 18775869 15825163 24130169
ITGAV L1CAM â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 11553709 19161977 8636223 9003039
ITGAV ITGB3 â—¼   PHYSICAL_INTERACTION 23.0 1.0 ACSN 10022831 10545505 10837075 11146654 11335727 11532940 11553709 12000961 14697347 15031725 16919435 18353785 19161977 19339212 19449109 22035837 7512751 7529872 7657702 8636223 8755653 9295024 9763615
ITGAV ITGB3 â—¼   SHARES_COMPLEX 23.0 1.0 ACSN 10022831 10545505 10837075 11146654 11335727 11532940 11553709 12000961 14697347 15031725 16919435 18353785 19161977 19339212 19449109 22035837 7512751 7529872 7657702 8636223 8755653 9295024 9763615
SP1 ITGAV â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10504395 23319049 12136940 23345412
ITGB3 L1CAM â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 11553709 19161977 8636223 9003039
SRC ITGB3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 36.0 1.0 Omnipath 10330414 17473008 8631894 18156175 25694433 18840695 18364349 18398066 10592173 16935858 21956114 17353363 18088087 12359711 15212693 14996908 15695822 15699036 11723131 20702409
SNAI2 L1CAM â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20799950 21109948
RPS6KA2 L1CAM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 8663493
RPS6KA1 L1CAM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8663493
MAP2K1 MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 149.0 1.0 Omnipath 21675959 9694850 17081983 10757792 11319218 18799465 15592455 12788955 19415658 12697810 17389395 9447970 15342917 8226933 15851026 12270934 12644307 17255949 10998418 11242034 1378617 1381507 17906627 11986622 8376945 8157000 7992057 11948414 9731057 19651622 11251083 11266467 18707149 14743221 11279118 11704645 12750173 12932319 16497976 11337027 23331499 12048245 7559390 17272394 15811950 19494114 18669648 18691976 11741894 15972258 19053285 16094384 17192257 7898932 24623782 9166761 19369195 21336309 12920017 15466214 17016520 19901323 1712480 19690332 11823456 9032297 11134045 12876277 19534553 10995751 20068231 21506533 8223433 8248196 16153436 12594221 10567369 19933846 17563371 11730323 29175850 11352917 16135787 15951569 19058874 15212693 23241949 9560161 91184134 18083107 16887817 18578522 17569879 21071413 9148935 18452278 1330321 8670897 19541618 10777511 15935618 12925710 11971971 9765155 11136732 11118451 12082107 12952943 10746662 21768338
SP1 MAPK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 12220517 16797880 20506264 20121399 20882567 18372343 10727414 21170990 17889508
PEA15 MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 23331499 14506247 32296183 11702783 17255949
MAPK1 RPS6KA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 8939914 12832467 9915826 17906627 32296183 19282669
MAPK1 RPS6KA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 60.0 1.0 Omnipath 17081983 32814053 20385094 11532940 7601337 23331499 15342917 8939914 21071413 23047924 20068231 11335727 9687510 12618428 18988627 18669648 23519423 23109003 18691976 12594221 9915826 17906627 8202512 9430688 19651622 12832467 11500364 14966081 29997244 25730857 8387505 10411321 18212344
MAPK1 SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 19318349 20882567 16377629 18775330 8226933 14744793 16079281 11904305 9604935 15212693 14593115 8388392
SP1 TGFB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 12186868 9580699 2808430 12615726 22415074 27974707 12138160 10964912 9242631 15178441 23437118 23936544 11114293 8325508 16714330 11278686 10212284 9837963 11054406 23806282 15979845
SPTA1 SPTAN1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 22013193 19758564 24119662 19164740
SRC SPTAN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 12446661 11971983
TGFB1 SRC â—¼   ENZYMATIC_REACTION ✅ 56.0 1.0 ACSN 10671552 11133108 11348595 11476890 11955436 11967263 12051714 12426320 14557817 15001769 15279786 15548370 16039586 16099633 16371504 16474430 16919435 17143292 17303408 17496910 17517963 17660363 17928543 17934056 17936032 18037882 18590585 19010789 19029934 19109155 19171760 19619488 19734908 19920116 20519943 20644162 20705860 21278795 21666923 21900405 22007144 22174153 22203675 22370635 22674073 22703233 23343194 24023259 25572304 25730849 26552706 27216177 7542250 7575488 7594497 8666229
WRN WRN â—¼   KO_DOWN_REGULATES ✅ - -3.6 3.59 PKG 28854368