Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
ZRANB1 UBC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19373254 7288828
UBC ZRANB1 â—¼   DEUBIQUITINATION ✅ 2.0 0.8 intact 19373254 7288828
PDIA3 ITGB5 â—¼   DISULFIDE_BOND ✅ 2.0 0.8 intact 17170699 5219449
ITGA4 ITGB7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 12626562 19454690
LAMB1 GFI1B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
ESR2 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16549430 17261755
JUN AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12832543 11192249
CASP3 AKT1 â—¼   CLEAVAGE ✅ 2.0 0.8 intact 17544405 5219985
RHOA AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15884057 11748077
LAMB1 ATXN7L2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
CASP3 ITGB4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17178732
CASP3 CASP7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17899380
CASP7 ITGB4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17178732
LAMA5 CD151 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15677332 10842354
LAMB1 CD151 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15677332 10842354
CD44 ITGA4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21257905 1018064108
MMP14 CD44 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11381077 21385940
DAG1 PIK3R1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
LAMA5 DAG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16709410 10207021
EGF PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17496910 19531499
RARA EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 11788593
EGFR PIK3CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17496910 1845983
EGFR PTGS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19531499
ESR2 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10037443
RARA ESR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 9841885
ESR2 RARA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 9841885
HOXA1 LAMA5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
RARG HOXA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21087926 20231276
RARA HOXA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 25303530 19131338
HR L1CAM â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17903170 21150308
ITGA2 PDIA3 â—¼   DISULFIDE_BOND ✅ 2.0 0.8 intact 17170699 5219449
PDIA3 ITGA3 â—¼   DISULFIDE_BOND ✅ 2.0 0.8 intact 17170699 5219449
ITGA6 ITGB4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 19161977 22118458
PDIA3 ITGA6 â—¼   DISULFIDE_BOND ✅ 2.0 0.8 intact 17170699 5219449
LAMA2 ITGA6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7721947 32196115
ITGB3 ITGAV â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5214491 11546839
PDIA3 ITGB1 â—¼   DISULFIDE_BOND ✅ 2.0 0.8 intact 17170699 5219449
LAMA2 ITGB4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7721947 32196115
UBC JUN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7104155 19343052
JUN UBQLN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
JUN RARB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9377582
JUN PTGS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17138645
RARA LAMB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 2556699 8645318
NANOG LAMB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15983365
RARB LAMB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 1646397 2556699
LAMB1 PDIA3 â—¼   DISULFIDE_BOND ✅ 2.0 0.8 intact 17170699 5219449
LAMC1 PDIA3 â—¼   DISULFIDE_BOND ✅ 2.0 0.8 intact 17170699 5219449
MMP14 TGFB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 21909923 21900405
RAC1 PIK3CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9148763 10592173
PIK3CA RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9148763 10592173
RARA PRKCA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11525643
RAC1 PRKCA â—¼   COLOCALIZATION 2.0 0.8 intact 5218533 16628218
RORA PSMC5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
RARG RARA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17291686 1650576
RARB RARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 1320193
UBC RHOA â—¼   UBIQUITINATION ✅ 2.0 0.8 intact 5217531 15710384
CAV2 EGFR â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
PIK3R1 EGFR â—¼   PHYSICAL_INTERACTION ✅ 0.81 0.81 mint 16273093 5218056
ITGA2 ITGB1 â—¼   PHYSICAL_INTERACTION 811.0 0.81 STRING 36370105
ITGA5 ITGB3 â—¼   PHYSICAL_INTERACTION 818.0 0.81 STRING 36370105
LYZL2 OS9 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
LYZL2 LAMB1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
COL12 LAMB1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
IFIX LAMB1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28077445 25665578
IFIX LAMC1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28077445 25665578
DEF1 TGFB1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
DEF1 LAMA3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
DEF1 LAMA5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
DEF1 LAMB1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SPA12 LAMB1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CD79A BCAM â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
BCAM LAMA4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
BCAM LAMB1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CD44 LAMA3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CRP LAMA5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CRP LAMB1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CRP LAMA1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
OS9 LAMA5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
TGFB1 LAMB1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 20936779 27684187
OS9 LAMB1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
PSG8 LAMB1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RAC1 UBB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 31980649
UBB ZRANB1 â—¼   PHYSICAL_INTERACTION 823.0 0.82 STRING 36370105
EGFR LEG3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 21258405 19225046 23956138
IFIX LEG3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
LEG9 LEG3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
LEG3 COL12 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
LEG3 LAMB1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
LEG3 LAMA4 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
LEG3 LAMA1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
LEG3 PTPRK â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
LEG9 COL12 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
LEG9 LAMB1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
LEG9 PTPRK â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
LEG9 DAG1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
LEG9 LAMA1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
LEG9 LAMA4 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
DMD DISC1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 17043677 31413325 90000000
PTPRK EGFR â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
PTPRK LAMA3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
PTPRK LAMA5 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
PTPRK LAMB1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
TGFB1 LAMC1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
RARA RARG â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 25303530
DAG1 LAMA5 â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
ITGB6 TGFB1 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
EGFR CD44 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 23265944 12093135 16565089 15597342 11606076
RARA RARB â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 33961781 28514442 22022577
UBB UBC â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
ITGA4 ITGB1 â—¼   PHYSICAL_INTERACTION 844.0 0.84 STRING 36370105
ITGAV ITGB1 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
PSMC5 RARA â—¼   PHYSICAL_INTERACTION 854.0 0.85 STRING 36370105
RARA AKT1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 23693014 16417524
CDC42 PIK3R1 â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
PSMC5 UBB â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
CD151 ITGA3 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
LAMC1 LAMB1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 17517882
AKT1 PIK3CA â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
CDC42 RAC1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 31871319 9427749
ITGA1 ITGB1 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
EGFR AKT1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 31980649 25402006 24658140
EGFR PIK3R1 â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
PSMC5 UBC â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
LAMA2 ITGA7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11278916
UTRN DRP2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 20625412 11430795 11430802
AKT1 ITGB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16256741 10896934
LAMA5 BCAM â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 28514442 12244066 11133776
EGFR CAV2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 31980649 24658140 25402006 16799092 15273741
NR2F1 CD44 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10644740 11682620 12943729
UTRN DAG1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 20625412 11430795 11430802
DMD DAG1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 10932245 7592992 19109891 10355629
LAMA1 DAG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11798066 16709410 7925941
EGF RHOA â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18955552 20937854 15156151
EGFR RHOA â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18955552 20937854 15156151
PTPRK EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 16263724
LAMC1 ITGA3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11964076 16413178 16581764
LAMA5 ITGA3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11964076 16413178 16581764
LAMB1 ITGA3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11964076 16413178 16581764
ITGA3 LAMA3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11964076 16413178 16581764
LAMA5 ITGA6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11964076 16413178 16581764
LAMC1 ITGA6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11964076 16413178 16581764
LAMB1 ITGA6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11964076 16413178 16581764
LAMA5 ITGA6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10671376 11733063 32196115
LAMA5 ITGB1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11964076 16413178 16581764
ITGB1 LAMB1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11964076 16413178 16581764
ITGB1 LAMC1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11964076 16413178 16581764
LAMA2 ITGB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11278916
LAMB1 ITGB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10842354
PRKCA ITGB3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16014375 10592173 17570479
LAMC1 ITGB4 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11964076 16413178 16581764
LAMB1 ITGB4 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11964076 16413178 16581764
LAMA5 ITGB4 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11964076 16413178 16581764
LAMA5 ITGB4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10671376 11733063 32196115
LAMA3 ITGB4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12867433 8143784 32196115
JUN NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16713569 7823959 8733011
LAMA2 UTRN â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 20625412 11430795 11430802
LAMB1 UTRN â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 20625412 11430795 11430802
LAMC1 UTRN â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 20625412 11430795 11430802
PRKCA RHOA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10592173 11284700
PRKCA RARA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8145770 12000751 10608897
UTRN PRX â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 20625412 11430795 11430802
DAG1 UTRN â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
LAMA5 LAMB1 â—¼   PHYSICAL_INTERACTION 907.0 0.9 STRING 36370105
ITGA6 ITGB1 â—¼   PHYSICAL_INTERACTION 911.0 0.91 STRING 36370105
LAMA2 DAG1 â—¼   PHYSICAL_INTERACTION 0.92 0.92 HIPPIE 16709410 7925941
DAG1 DMD â—¼   PHYSICAL_INTERACTION 921.0 0.92 STRING 36370105
HOXA1 TGFB1 â—¼   PHYSICAL_INTERACTION 0.92 0.92 HuRI 32296183
LAMA5 DAG1 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 30914516 10207021
DAG1 LAMA1 â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
UBC UBQLN1 â—¼   PHYSICAL_INTERACTION 954.0 0.95 STRING 36370105
ITGAV TGFB1 â—¼   PHYSICAL_INTERACTION 963.0 0.96 STRING 36370105
LAMA5 LAMC1 â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
DAG1 LAMA2 â—¼   PHYSICAL_INTERACTION 967.0 0.96 STRING 36370105
EGFR EGF â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 25453753 30083275 21822280 12620237 19531499 25080504 12093292 22729867 23597562 18427122 26280537 18271526 10970856 15620700 11684674 21439278 8663535 28988771 2790960 10788520 10085134 16274239 25241761 17697999 9135143 12297050
PIK3R1 PIK3CA â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 20018188 7383613
LAMB1 LAMC1 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
UBC ZRANB1 â—¼   PHYSICAL_INTERACTION 979.0 0.97 STRING 36370105
EGF EGFR â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
ITGA5 ITGB1 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
ITGA2B ITGB3 â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
PIK3CA PIK3R1 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
ITGAV ITGB5 â—¼   PHYSICAL_INTERACTION 9.0 1.0 ACSN 10837075 11146654 14697347 15031725 18353785 22035837 22470492 9295024 9763615
ITGAV ITGB5 â—¼   SHARES_COMPLEX 9.0 1.0 ACSN 10837075 11146654 14697347 15031725 18353785 22035837 22470492 9295024 9763615
ITGB5 ITGA1 â—¼   DOWN_REGULATES ✅ - 5.0 1.0 ACSN 22470492 24309651 26519775 9295024 9763615
ITGB5 ITGA2 â—¼   DOWN_REGULATES ✅ - 5.0 1.0 ACSN 22470492 24309651 26519775 9295024 9763615
LAMA1 ITGB8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 7542940
LAMA1 ITGA7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11278916
DRP2 DAG1 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 11430795 8349731 20625412 22764250 11430802 19321787 7925941 11115854 8627307
LAMC1 DRP2 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 11430795 8349731 20625412 22764250 11430802 19321787 7925941 11115854 8627307
LAMA2 DRP2 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 11430795 8349731 20625412 22764250 11430802 19321787 7925941 11115854 8627307
LAMB1 DRP2 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 11430795 8349731 20625412 22764250 11430802 19321787 7925941 11115854 8627307
RAC1 AKT1 â—¼   ENZYMATIC_REACTION ✅ 45.0 1.0 ACSN 10722653 10949026 11274345 11715018 11756412 11756498 11923280 12408816 12906785 15169778 15808505 16469695 16697215 17052453 17461779 17680028 18000759 18372248 18492954 18570873 18636226 18925875 19022819 19143635 19151919 19568798 19720745 20027184 20138985 20214616 20338997 20398329 20832730 21157483 21474067 21981924 23087689 24795729 24973821 25002027 25730849 26159692 27331412 28216025 9812896
PIK3R1 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10527852 16799564 19442713
PIK3CA AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 25793261 19117013 21041639 24950409 21816939
CASP3 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 17544405 12124386 10579725
RAC1 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 34.0 1.0 Omnipath 18000759 20027184 21157483 11756412 11923280 16697215 20398329 17461779 18372248 20338997 15808505 20138985 20214616 21474067 19568798 15169778 19720745 18925875 10949026 11715018 19143635 12393431 18636226 10617634 9812896 17680028 19151919 10722653 20832730 18570873 17052453 12408816 11274345
AKT1 ITGB3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 18578522 10896934
AKT1 NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 27997540 24291004
AKT1 RARA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 16417524
PIK3R1 CDC42 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 7629060 8034624 9381982
CDC42 PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 7629060 8034624 9381982
COL18A1 ITGB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12682293
COL18A1 ITGA5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 11158588 12682293
LAMA2 DAG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 30530204 16709410 7925941
EGF EGFR â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 ACSN 15003992 15175028 15466195 15958574 18423981 19631971 20430953 21098712 8101258
EGF RHOA â—¼   DOWN_REGULATES ✅ - 10.0 1.0 ACSN 12094222 15003992 15175028 15466195 15958574 18423981 19631971 20430953 21098712 8101258
JUN EGF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 15075211 15772294 19937979 15375216 10617690 18625220 15238218 7629150 8885243 12954631 10973489 16214953 14518567
EGF EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 131.0 1.0 Omnipath 17145710 17081983 21822280 20813200 23613900 9135143 25453753 21303971 10209155 26821125 12297050 27387652 25241761 30083275 12093292 30197274 21649524 19531499 18762250 16729043 26921391 17697999 17575160 21722395 12620237 19129184 10788520 23331499 3494473 15620700 14568001 15958209 24096486 18253097 16843263 18320059 21532939 10085134 22260327 15708576 26280537 23912460 21858221 11116185 10970856 27462018 18427122 25080504 20953304 19135477 11684674 8639530 27564112 18270696 2790960 17971399 23185569 19895983 28988771 29617357 23597562 19531623 23950932 21071413 8663535 6289330 16274239 17563729 21439278 20458382 22216880 18271526 12771140 21311755 24709886 25366117 12648462 21107857
PTGS2 EGFR â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 18633355 20138012 21847358 23010081 23390297 25987127
JUN EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 16170369 23455325 15923621 16423552 10803405 18604200
PRKCA EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 39.0 1.0 Omnipath 11447289 8321321 11313945 25402006 12040186 20888375 15302935 6321473 1860884 12878187 6090944 19568798 14585353 17496910 21386996 24658140 2984676 11940581 31980649 15212693 85012702 19615955 2987962 12845332 3379075 7805884 10816576 15567848 16488589
TGFB1 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20953304 32103204 19132220 28943431
EGFR PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 17496910 26918608 7797556 25241761 19531499 16273093 8662998 14967450 16713569 21701776
ITGA11 MMP14 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 17420280 17600088 19913614 20129924 25076207 26148229
LAMA1 ITGA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9688542
TGFB1 ITGA3 â—¼   PHYSICAL_INTERACTION 48.0 1.0 ACSN 10671552 11133108 11348595 11955436 11967263 12051714 12426320 14557817 15001769 15279786 15548370 16039586 16099633 16371504 16474430 17143292 17303408 17660363 17928543 17934056 17936032 18037882 18590585 19010789 19029934 19109155 19171760 19619488 19734908 19920116 20519943 20644162 20705860 21278795 21666923 21900405 22007144 22174153 22203675 22674073 22703233 23343194 24023259 25730849 7542250 7575488 7594497 8666229
TGFB1 ITGA3 â—¼   SHARES_COMPLEX 48.0 1.0 ACSN 10671552 11133108 11348595 11955436 11967263 12051714 12426320 14557817 15001769 15279786 15548370 16039586 16099633 16371504 16474430 17143292 17303408 17660363 17928543 17934056 17936032 18037882 18590585 19010789 19029934 19109155 19171760 19619488 19734908 19920116 20519943 20644162 20705860 21278795 21666923 21900405 22007144 22174153 22203675 22674073 22703233 23343194 24023259 25730849 7542250 7575488 7594497 8666229
ITGB1 ITGA4 â—¼   PHYSICAL_INTERACTION 9.0 1.0 ACSN 12626562 19161977 19454690 19487819 22470492 9003039 9456329 9763606 9973479
ITGB1 ITGA5 â—¼   PHYSICAL_INTERACTION 29.0 1.0 ACSN 10461188 10545505 10559936 10613909 11340065 11413130 11950587 12731048 15866889 16076871 16919435 17522712 18037882 19161977 19339212 19454690 19487819 20644254 20814939 22067905 22154077 22470492 24202395 7529872 7657702 9003039 9456329 9763606 9973479
LAMB1 ITGA6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 7721947 11733063 10842354
LAMC1 ITGA6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 7721947 10671376 11733063 32196115
ITGAV L1CAM â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 11553709 19161977 8636223 9003039
ITGAV ITGB3 â—¼   PHYSICAL_INTERACTION 23.0 1.0 ACSN 10022831 10545505 10837075 11146654 11335727 11532940 11553709 12000961 14697347 15031725 16919435 18353785 19161977 19339212 19449109 22035837 7512751 7529872 7657702 8636223 8755653 9295024 9763615
ITGAV ITGB3 â—¼   SHARES_COMPLEX 23.0 1.0 ACSN 10022831 10545505 10837075 11146654 11335727 11532940 11553709 12000961 14697347 15031725 16919435 18353785 19161977 19339212 19449109 22035837 7512751 7529872 7657702 8636223 8755653 9295024 9763615
PRKCA ITGB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12138200 12435334 20926684 11700305 10592173
ITGB3 L1CAM â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 11553709 19161977 8636223 9003039
PRKCA ITGB4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 17615294 12919677 15121854 19005215 10592173 10477766 22824799 20870721
LAMC1 ITGB4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 7721947 10671376 11733063 32196115
LAMB1 ITGB4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 7721947 11733063 10842354 32196115
ITGB4 PIK3CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 9428518 11733063 12867433 7721947 8143784
NR3C1 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 20499359 8639160 2169353 9731701
JUN PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 33.0 1.0 Omnipath 11901151 16001969 19783677 15238218 23523690 10668496 16007171 12057991 22472290 18294142 16339564 17556653 9830045 9988750 19825968 15994313 15772294 9620167 9686761 15525691 11356200 16256955 11234900 18097055 11980644 9705326 19522015 11278336 18282182 12086396 10811116 20237399
JUN TGFB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 8058069 16327802 16730810 23437118 8183578 16365456 22429882 23936544 15546613 10843986 16978906 23762330 7521696 8631909 12794825
LAMA2 PRX â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 11430795 8349731 20625412 22764250 11430802 19321787 7925941 11115854 8627307
LAMB1 PRX â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 11430795 8349731 20625412 22764250 11430802 19321787 7925941 11115854 8627307
LAMC1 PRX â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 11430795 8349731 20625412 22764250 11430802 19321787 7925941 11115854 8627307
NR3C1 PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 10631313 18945810 10827178 18657608 9918831 19797430 10701683 18650268 16198345
PIK3R1 RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 7629060 8034624 12086876 12515821
PRKCA RAC1 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 10679481 10871288 16492141 18851840 20027184 21474067
PRKCA RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 16628218 20027184 11284700 18851840 21474067
RARA RARB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 10929206 16613989 7969156 8388240 2164682 1316240 8001825 1650576 16832676 16782888 10629053 2153268 9108446 1318502 10629091 11839811 11497266 9184230 14528273
RARA RARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16081280 1320193
RARG RARB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 1310259 10075839 10929206 1650576