Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
ITGB1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SP1 COL18A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11093745
TP53 COL18A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
NFIC COL18A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11093745
TP53 COL18A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15958553
NFIC COL1A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10082137 7504695
SP1 COL1A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19558215
TP53 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10766163 16713569
NFIC ITGA5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18775869
SP1 LAMC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12034813 9403717
ESR1 TP53 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
ESR1 FOXA1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 23403292 25303530 28336670 27926873
ITGAV ITGB1 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
LATS1 ITCH â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 28416659 21212414 21383157 24107629 23564455 34079125
ITCH LATS1 â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
LAMC1 LAMB1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 17517882
COL4A1 ITGB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8223488
FOXA1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21572391 20501593 24290378
ESR1 SPARC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20034404
ITGAV KDR â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 12820653 19267251 17030947
ITGB1 LAMB1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11964076 16413178 16581764
ITGB1 LAMC1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11964076 16413178 16581764
LAMB1 ITGB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10842354
ESR1 SP1 â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
SP1 TP53 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
LAMB1 LAMC1 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
ITGA5 ITGB1 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
SP1 APP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 19049493 8427604 15673661 9361293 21557719 18449948 14701757 8015372
ESR1 CAV2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12711000 12138116 18414489
COL18A1 ITGB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12682293
COL18A1 GPC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11336700 11336704
COL18A1 ITGA5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 11158588 12682293
SP1 COL1A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 10091149 16575855 9666093 10775443 12138160 11348466 17698844 16564026 10082137 7504695 7590335
COL1A1 ITGB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 7716514 10464311 7688313
COL1A1 ITGA5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 1693626 16189514
COL4A1 ITGAV â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 14610079
SP1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 12237165 19351845 11345900 21235772 23209644 12429135 18006846 10982795 22622808 15691879 21191649
ESR1 KDR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16574784 18006642
ESR1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 20080630 16115928 22787161 12750288 20696891 17681750 17699779
ITGB1 ITGA5 â—¼   PHYSICAL_INTERACTION 29.0 1.0 ACSN 10461188 10545505 10559936 10613909 11340065 11413130 11950587 12731048 15866889 16076871 16919435 17522712 18037882 19161977 19339212 19454690 19487819 20644254 20814939 22067905 22154077 22470492 24202395 7529872 7657702 9003039 9456329 9763606 9973479
SP1 ITGA5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 22227038 18775869 15825163 24130169
SP1 ITGAV â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10504395 23319049 12136940 23345412
THBS1 ITGB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15292271
THBS1 KDR â—¼   DOWN_REGULATES ✅ - 6.0 1.0 ACSN 10657674 11982756 14568985 14996710 22943793 8349738
SP1 KDR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 19888537 14684628 15111490 12560084 19469899 21980525 16678129 18006642 9079666 12067897 21430706 16574784
TP53 SP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 19846904 15790310 11118296 11384995 21611785 7478550 15967108 18419600 19244234 9865734 18769160
TP53 THBS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 12609716 10719731 10101800 24195060 10029407 16406676 19826414 9833779 12719977 9017002 22028325 10224095 9849855 7521539
TP53 KDR â—¼   KO_UP_REGULATES ✅ + 1.12 1.12 PKG 28854368