Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
FYN CSK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7524477 6730342
CSK PTPRC â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 6672875 7507203
ELF2 BLK â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8756667 14970218
RUNX1 BLK â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10455134 14970218
PAX5 BLK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10455134
RUNX1 BLK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10455134
PAX5 CD19 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15676205
CD79A FN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6491104 18243143
ID1 CD79A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12446773 18641300
RUNX1 CD79A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20385820 15361869
FLI1 CD79A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14500810 18641300
PAX5 CD79A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15676205
FOXN1 CHD4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20693977 23444401
ETS2 EGR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9207063
EGR1 PTEN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12384981
ETS2 HMOX1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15590657 20348279
ETS2 FLI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19829305
FYN FANCA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
PLCG1 FANCA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
FANCA GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
TMEM11 FATE1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
SMAD7 FN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19397700 12207925
FYN GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9694876 7737275
FYN HMOX2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
LYN GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9209406 8400282
GRB2 SMAD3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
GRB2 TUBB3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 TUBA4A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 RPL23 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
STAT1 HMOX1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19129475
SMAD4 ID1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19079362 12296825
ID1 ID2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 9779825 19896442
ID2 TUBB3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 22380883 23878399
RUNX1 IER3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16368886
INPP5D SYK â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 32323266 22267732
LYN SOS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9209406 8400282
LYN PLCG1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15644415 8034732
RUNX1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 29958106
MYC RPL23 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14519204 11085504
STAT1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10637230
WFS1 PHF5A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RASA1 PLCG1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6805619 9020117
RASA1 PLCG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 9020117 9743338
RPL23 TMEM147 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
SMAD4 RUNX3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16135801 10531362
TYK2 STAT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15261459 23124025
VTI1B STX8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
WFS1 YIF1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SLC38A1 SMIM3 â—¼   PHYSICAL_INTERACTION 0.8 0.8 HuRI 32296183
SYK PLCG1 â—¼   PHOSPHORYLATION ✅ + 0.8 0.8 Signor 8657103
SLC13A4 SLC41A1 â—¼   PHYSICAL_INTERACTION 0.8 0.8 HuRI 32296183
GRB2 HCLS1 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 9670936
NAT8 YIPF4 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HuRI 32296183
GRB2 CSK â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21706016 31980649
CD79A ATP23 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CD79A CDYL1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CD79A DD19B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
DD19B HMOX1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
CD79A RL23 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CD79A NDKM â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CD79A TBB8 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CD79A MET15 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CD79A NOCT â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
GTPB5 SYHM â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 32877691
CD79A GTPB5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CD79A NTCP7 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CD79A SYHM â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CD79A PAPD1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CD79B KMCP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CD79A KMCP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CD79A GTR8 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CD79A GTPB6 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CD79A BCAM â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
BCAM LAMB1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
STX12 BET1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29568061 26344197
LYN CD19 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 7589101 7568175 15187135 10933394
CD79A UFSP2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CD79A TTC28 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CD79A PEX6 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CD79A DEGS1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CD79A TYK2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CD79A NEK4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CD79A MICU1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CD79A PEX16 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
TECR JAGN1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 32296183 26344197
MYC SYK â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21150319 29467282
MYC RUNX1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21150319 29467282
SMAD3 RUNX1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 10531362 15897867
VAMP3 STX8 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 19557002
STX12 VTI1B â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
HCLS1 CD79A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 16713569 7927516
HMOX2 PRAF2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
VTI1B STX12 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
STX12 VAMP3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
EMP3 SMIM3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HuRI 32296183
STX3 VAMP3 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
DOK1 INPP5D â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
RASA1 GRB2 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 12441060 16189514 16713569
STAT1 MTOR â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 19553685 25241761 12807916
VTI1B VAMP3 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 33961781 28514442 26186194 27791468
YIF1A YIPF4 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HuRI 32296183
SMIM3 TMEM218 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HuRI 32296183
PLCG1 RASA1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 9743338 9020117 8977179
SMAD3 RUNX3 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 27497248 10531362 15138260
YIF1A VAPA â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 26496610 23736259
CSK PTPRC â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 19167335 7507203
CD79B CD79A â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 1591006 12886015 8656670 9531288
VAPA FKBP8 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 32877691 26496610
GRB2 INPP5D â—¼   PHYSICAL_INTERACTION 869.0 0.86 STRING 36370105
CD79A AMBP â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 9183005 6196366
VAPA VAPB â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
SMAD4 SMAD7 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
FATE1 SLC41A2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
FATE1 OTOP2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
LYN DOK1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 11071635 11825908
ELF2 RUNX1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 14970218 10207087
FATE1 SLC7A1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
FATE1 SLC38A1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
MYC CHD4 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 30415952 17314511 29467282
ELF4 RUNX1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 14970218 10207087
TYK2 FYN â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 9196040 16713569 16189514
DOK1 RASA1 â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
ATP6V0C SMIM3 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
FN1 CSK â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16040750 14754902 10446041
CSK BLK â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11489946 14967142 16537894
ETS2 BCL2L1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19411629 19179380 10082528
STAT1 BCL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19122651 15596057
MYC BLK â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
EGR1 CD19 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9233624
LYN CD79A â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 9547345 9601638 9480991
LYN CD79B â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 9547345 9601638 9480991
MYC CD79B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
FLI1 HMOX1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16310515 10022513
SMAD4 FN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19516008 15525600 17452626
SMAD3 FN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16469949 12207925 15525600
TFCP2 FN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21361876 25609232
FN1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18624398 19738201
FYN GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 7499280 9344857
SH2B1 GRB2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 9742218 32296183 9856458
RASA1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12441060 16713569
MYC IER3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12360408
MYC SMAD7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
PLCG1 SYK â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 7517665 8657103 15161916
SMAD7 SMAD4 â—¼   DOWN_REGULATES ✅ - 3.0 0.9 ACSN 11279127 15265520 23784029
GRB2 SOS1 â—¼   RELOCALIZATION ✅ + 0.9 0.9 Signor 23452850
FATE1 UNC93B1 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
TUBA4A TUBB3 â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
FATE1 YIPF4 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
FATE1 RTP2 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
FATE1 TMEM11 â—¼   PHYSICAL_INTERACTION 0.92 0.92 HuRI 32296183
CNIH3 SMIM3 â—¼   PHYSICAL_INTERACTION 0.92 0.92 HuRI 32296183
PLCG1 SYK â—¼   PHYSICAL_INTERACTION 936.0 0.93 STRING 36370105
STX8 VTI1B â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
SMCO4 SMIM3 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HuRI 32296183
CNIH1 SMIM3 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HuRI 32296183
SOS1 FYN â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 17474147 16713569 9856337
LYN HCLS1 â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 15795233 9104825 16713569 10066823 7682714
PLCG1 GRB2 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 21706016 7629168 10940929 16038803 9020117 16713569 9281317 7516467
SOS1 PLCG1 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 10913276 10940929 9020117 16713569 17474147
RPS6KB1 MTOR â—¼   PHOSPHORYLATION ✅ - 0.96 0.96 Signor 15905173
MTOR RPS6KB1 â—¼   PHOSPHORYLATION ✅ + 0.96 0.96 Signor 12782654
MTOR RPS6KB1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
GRB2 SOS1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
SMAD3 SMAD4 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
CSK FYN â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 10790433 11181701 12485116 15713798 19290918 8011291 8986721
CSK FYN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 1985196 8262983 11489946 16537894 9647655 25720756 18691976 10366594 19369195 1533589 1699196 7524477 16713569 15713745 14967142
CSK PTPRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 7507203 19167335
CSK LYN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 38.0 1.0 Omnipath 19901323 11489946 15626731 10415030 16497976 14967142 16537894 7935444 20068231 18452278 10592173 18669648 9171348 18691976 8612628 8794770 19651622 22711887 1722201
MYC BCL2L1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 14517295 18802399 16316993 17331788
FKBP8 BCL2L1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 16189514 12510191 15733859
CD79B BLK â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 Reactome 12453414 8306975 7524079 1702903 7927516 7592958 7688784
CD79A BLK â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 Reactome 12453414 8306975 7524079 1702903 7927516 7592958 7688784
PAX5 BLK â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 9660839 10553071 10455134 8759736 14594818 8195169 18697940
PAX5 CD19 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 7532151 12907641 20208555 7541987 8639790 9722295 1375324 10666449 15163413 11359826 17513763 18617575
LYN CD19 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 15187135 10706702 7568175 25673924 7589101 10201980 16497976 10933394 9190913 15212693 11809733
CD79A GRB2 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 12456653 9341187 9705962 19372136 11071869 11449366 11909947 9697839 21822214
CD79A SOS1 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 12456653 9341187 9705962 19372136 11071869 11449366 11909947 9697839 21822214
FYN CD79A â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 Reactome 12453414 8306975 7524079 1702903 7927516 7592958 7688784
CD79A SYK â—¼   ENZYMATIC_REACTION ✅ 8.0 1.0 Reactome 16849466 21469132 18052078 18818202 18006696 10648173 8163536 7538118
PAX5 CD79A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 14500810 19616560 18641300 10435576 11779502 15361869 9545244 9743352 8804314 12446773 12612069
LYN CD79A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 1506682 17570479 9531288 10748115 8183901
SYK CD79A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 30465710 12453414 7538118 7500027 20940318
FYN CD79A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 9531288 17570479 8183901 1506682
CD79B GRB2 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 12456653 9341187 9705962 19372136 11071869 11449366 11909947 9697839 21822214
CD79B SOS1 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 12456653 9341187 9705962 19372136 11071869 11449366 11909947 9697839 21822214
FYN CD79B â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 Reactome 12453414 8306975 7524079 1702903 7927516 7592958 7688784
CD79B SYK â—¼   ENZYMATIC_REACTION ✅ 8.0 1.0 Reactome 16849466 21469132 18052078 18818202 18006696 10648173 8163536 7538118
SYK CD79B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 7538118 12453414
LYN CD79B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 9531288 17570479 12453414 8077654
FYN CD79B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 9531288 8077654
LYN DOK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 11071635 11489946 16537894 11841937 11825908
FYN DOK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11489946 16537894 11841937 11825908 15345598
DOK1 RASA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10640270 11071635 10799545 9008161
EGR1 FN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 9933644 10783396 16138117 15608673
EGR1 PTEN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 17330857 17479230 20514024 12917634 17516844 15231710 18062928 18324520 11781575 20862322 16138117 21297666 20959484 16424010 15517593
PTEN ETS2 â—¼   DOWN_REGULATES ✅ - 13.0 1.0 ACSN 10753747 11747822 12040186 15721744 16288286 16982858 17218262 19847259 22179046 22465479 23732914 24254977 25364523
MYC ETS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18586674 12695333
FKBP8 MTOR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 24205284 17991864
FN1 FYN â—¼   ENZYMATIC_REACTION ✅ 14.0 1.0 ACSN 12731048 18037882 19161977 19454690 19487819 20644254 20814939 22067905 22470492 24202395 9003039 9456329 9763606 9973479
MYC FN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 14519204 11896591 8376401 10421838
SYK FYN â—¼   ENZYMATIC_REACTION ✅ 20.0 1.0 ACSN 10358164 11907067 12524384 14568985 15536084 17101731 19909365 20150200015 21149606 21378271 21910624 23609447 8189062 8226994 9000133 9295024 9314552 9396765 9632805 9763615
FYN GRB2 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 9822663 15886116 10849438 12670394
FYN PTPRC â—¼   ENZYMATIC_REACTION ✅ 17.0 1.0 ACSN 10591186 10648627 12218089 12414720 12731048 19290918 19909365 20814939 21378271 22683124 22863785 23620508 23886063 24440149 25312647 27192565 9738502
GRB2 FYN â—¼   DOWN_REGULATES ✅ - 52.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
PTPRC FYN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 1985196 8980254 11909961 1464315 1533589 9535845 16713569 9368621 12589038
FYN SYK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 7797565 7513017 17570479 10477689 9535867 16713569
FYN SOS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 17474147 16713569 9856337
FYN PLCG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8395016 10586033 7682059 16713569
SYK GRB2 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 12456653 9341187 9705962 19372136 11071869 11449366 11909947 9697839 21822214
SOS1 GRB2 â—¼   PHYSICAL_INTERACTION 1.0 1.0 HIPPIE 8810325 33961781 8695800 7510700 8626525 34407391 16520382 10570290 16906159 16893902 7642581 8816480 9447984 12577067 11964172 8112292 8493579 7664271 16713569 7516467 19380743 9009162 10207103 17474147 10477741 32062451 7629138 21706016 20473329 19323566 9872323 32203420 7514169 21988832 28166272 28514442 9716598 11997436 9344843 15192046 10716926 8479541 14679214 8943292 31980649 7629168 7559490 9478994 7527391 8188688 11960376 10025673 11726515 7773779 10319320 9569023 9797459
GRB2 SYK â—¼   PHYSICAL_INTERACTION 71.0 1.0 ACSN 10022831 10086337 10358164 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11907067 11960372 12175651 12393695 12524384 12629515 12640133 13678960 14568985 15099563 15111329 15501236 15520864 15536084 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17101731 17496910 17673906 17883421 19414323 19449109 19909365 20150200015 21149606 21372296 21378271 21910624 22064427 22461508 23390297 23609447 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8189062 8226994 8551221 8837607 9000133 9157999 9295024 9314552 9396765 9570538 9632805 9753319 9763615
GRB2 PLCG1 â—¼   PHYSICAL_INTERACTION 51.0 1.0 ACSN 10072481 10086337 10209041 10567412 10781611 10811803 10925299 10982827 11169415 11447289 11532940 11777939 11994416 12175651 12640133 1281218 12845332 14764585 15214048 15567848 15574420 16102570 16329184 16582911 16887996 1712101 17397400 17496910 17673906 19449109 19494291 19909365 23523669 23620508 24584707 25137453 2536067 25456276 25960930 26552706 7523143 7682895 7890616 8226994 8551221 8649391 8976179 8995379 9489702 9535722 9846483
GRB2 PLCG1 â—¼   SHARES_COMPLEX 51.0 1.0 ACSN 10072481 10086337 10209041 10567412 10781611 10811803 10925299 10982827 11169415 11447289 11532940 11777939 11994416 12175651 12640133 1281218 12845332 14764585 15214048 15567848 15574420 16102570 16329184 16582911 16887996 1712101 17397400 17496910 17673906 19449109 19494291 19909365 23523669 23620508 24584707 25137453 2536067 25456276 25960930 26552706 7523143 7682895 7890616 8226994 8551221 8649391 8976179 8995379 9489702 9535722 9846483
GRB2 SYK â—¼   SHARES_COMPLEX 71.0 1.0 ACSN 10022831 10086337 10358164 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11907067 11960372 12175651 12393695 12524384 12629515 12640133 13678960 14568985 15099563 15111329 15501236 15520864 15536084 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17101731 17496910 17673906 17883421 19414323 19449109 19909365 20150200015 21149606 21372296 21378271 21910624 22064427 22461508 23390297 23609447 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8189062 8226994 8551221 8837607 9000133 9157999 9295024 9314552 9396765 9570538 9632805 9753319 9763615
GRB2 SYK â—¼   ENZYMATIC_REACTION ✅ 71.0 1.0 ACSN 10022831 10086337 10358164 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11907067 11960372 12175651 12393695 12524384 12629515 12640133 13678960 14568985 15099563 15111329 15501236 15520864 15536084 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17101731 17496910 17673906 17883421 19414323 19449109 19909365 20150200015 21149606 21372296 21378271 21910624 22064427 22461508 23390297 23609447 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8189062 8226994 8551221 8837607 9000133 9157999 9295024 9314552 9396765 9570538 9632805 9753319 9763615
GRB2 PLCG1 â—¼   ENZYMATIC_REACTION ✅ 51.0 1.0 ACSN 10072481 10086337 10209041 10567412 10781611 10811803 10925299 10982827 11169415 11447289 11532940 11777939 11994416 12175651 12640133 1281218 12845332 14764585 15214048 15567848 15574420 16102570 16329184 16582911 16887996 1712101 17397400 17496910 17673906 19449109 19494291 19909365 23523669 23620508 24584707 25137453 2536067 25456276 25960930 26552706 7523143 7682895 7890616 8226994 8551221 8649391 8976179 8995379 9489702 9535722 9846483
PTEN GRB2 â—¼   REGULATES ✅ 15.0 1.0 ACSN 10648629 10753747 11747822 12040186 15584861 15721744 16288286 16982858 17218262 19847259 22179046 22465479 23732914 24254977 25364523
SYK GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11964172 16189514 22267732 10747947
PTEN GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 16288286 10648629 17218262 12040186 15584861
GRB2 SOS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 145.0 1.0 Omnipath 9544989 9872323 7642581 15746962 11726515 8621483 23334917 16520382 11997436 21706016 10359574 8950973 7664271 16713569 16893902 16906159 21988832 19323566 9009162 10716926 11964172 7629168 9815779 10592173 9716598 8647802 28166272 7773778 7773779 18778683 8188688 10319320 8810325 9344843 23452850 11960376 8816480 10025673 7510700 8940013 12955078 9697839 12345678 10477741 8493579 8943292 12577067 7862167 9199344 8112292 7898932 10207103 8695800 19531499 10570290 7760801 20005866 19380743 9447984 8235613 8479540 7527391 14679214 8479541 17474147 7514169 7629138
GRB2 PLCG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 9281317 15953601 7629168 9020117 16713569 10940929
GRB2 INPP5D â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 10660611 32323266 15456754 10748054 17043143 9108392 10900203 10068665 10891441 22267732 8723348
SYK HCLS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 16782030 8578591 15795233 21444687 9104825 9183008 25723543 15166239 23001182 96108162 18587398
LYN HCLS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 8578591 9104825 9183008 10066823 17570479 96108162 16713569 23001182 15795233 7682714
MYC HMOX1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12695333 10600159
SMAD4 ID1 â—¼   DOWN_REGULATES ✅ - 13.0 1.0 ACSN 11074002 11279127 11792802 12702545 12809600 15265520 16713975 16831886 17490644 18832382 21614932 23850759 9389648
SMAD4 ID1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 9389648 18832382 16831886 11074002 17490644
MYC ID2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12447693 12695333 12824180 18437010 18483244 12545167
PTPRC LYN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 7525568 12393728 7499277 10415030
LYN SYK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 9820500 24129562 10022120 18818202 21469132 24607955 18083107 17389395 19285079 11536198 10592173 25045209 7797565 11380624 9857068 7513017 30923129 8621719 10477689 7831290 15701717 27258042 19369195 28082678 8666899 9535867 8657103 14871838
LYN PLCG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 45.0 1.0 Omnipath 17389395 12601080 8395016 16038803 10586033 1689310 20068231 1708307 7682059 8885868 15144186 16497976 8657103 15592455 16126727 17016520 16153436
MTOR MYC â—¼   ENZYMATIC_REACTION ✅ 23.0 1.0 ACSN 12150925 12408816 12906785 15755954 16469695 17604271 17680028 18372248 18492954 19022819 19446321 19568798 19706736 19864431 21157483 21981924 23087689 24795729 24973821 25002027 25730849 26159692 28216025
MTOR RPS6KB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 111.0 1.0 Omnipath 25062042 17510057 17081983 15208671 22873724 16922504 23077579 12087098 28270148 16286006 15896331 25356520 17664694 21790669 26919095 26313911 21561857 10567431 16099428 21977024 14679009 11940578 15899889 15388791 12829246 21980324 22751450 12604610 9465032 20068231 10601311 28122439 19302577 21602892 15718470 15631631 23273915 18669648 21307646 10579915 23261705 20169205 25936802 25486097 24411482 12586835 23342114 15809305 14560963 22472346 11279232 15760907 9271440 27856330 12370290 23486913 12782654 11914378 24795562 19877273 28242756 11500364 26698305 14993219 20459645 23029019 16964243 15212693 25505994
SMAD4 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 11689553 17132729
SMAD3 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 15930298 20516082 14993291 17132729 16205635 25238097 11689553 17114344
MYC PTEN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23135913 19578399 12695333
MYC SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23331499 11804592
SYK PLCG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 54.0 1.0 Omnipath 17081983 19690332 8627166 16497976 15592455 16126727 17389395 19534553 1689310 20068231 10592173 16153436 16038803 1708307 7682059 15144186 9697839 7831290 7744830 12601080 8885868 8657103 17016520
PLCG1 SOS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 15953601 12084069 7629168 9020117 16713569 10913276 17474147 10940929
PTEN SOS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 16288286 10648629 17218262 12040186 15584861
PTPRC TYK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 11201744
TBX21 RUNX1 â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 ACSN 10761931 12055627 12802010 14614857 15084276 16410834 17440449 18768831 26885856
RUNX3 RUNX1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 17488194 15688019 19403666
SMAD4 SMAD3 â—¼   PHYSICAL_INTERACTION 72.0 1.0 ACSN 10454538 10925299 10964912 11007770 11013125 11013220 11074002 11114293 11224571 11279127 11283613 11283614 11376132 11399519 11792802 11875494 12193690 12545156 12702545 12809600 14976548 15001984 15095404 15155580 15265520 15644117 16127449 16179589 16713975 16831886 17018611 17055429 17260466 17550342 17563753 17689680 17705132 18353785 18768831 18832382 19208835 19597490 19815509 19901969 20027199 20713526 20731704 21041997 21042762 21098712 21252118 21317430 21577210 21614932 2191300 22331441 22514743 22652804 23140366 23338822 23390297 23784029 23869868 25374926 6357187 8515656 8871614 8893010 9312026 9389648 9618481 9670020
SMAD3 SMAD7 â—¼   PHYSICAL_INTERACTION 13.0 1.0 ACSN 11279127 11792802 12702545 12809600 15265520 16179589 16713975 18768831 21042762 21614932 22331441 23784029 8515656
SMAD3 SMAD7 â—¼   DOWN_REGULATES ✅ - 13.0 1.0 ACSN 11279127 11792802 12702545 12809600 15265520 16179589 16713975 18768831 21042762 21614932 22331441 23784029 8515656
SMAD3 TBX21 â—¼   DOWN_REGULATES ✅ - 25.0 1.0 ACSN 10925299 11074002 11279127 11399519 11792802 11875494 12193690 12702545 12809600 15265520 15644117 16127449 16179589 16713975 17260466 17689680 18768831 21042762 21614932 22331441 23390297 6357187 8515656 8871614 9389648
SMAD4 SMAD3 â—¼   LOCALISATION ✅ 72.0 1.0 ACSN 10454538 10925299 10964912 11007770 11013125 11013220 11074002 11114293 11224571 11279127 11283613 11283614 11376132 11399519 11792802 11875494 12193690 12545156 12702545 12809600 14976548 15001984 15095404 15155580 15265520 15644117 16127449 16179589 16713975 16831886 17018611 17055429 17260466 17550342 17563753 17689680 17705132 18353785 18768831 18832382 19208835 19597490 19815509 19901969 20027199 20713526 20731704 21041997 21042762 21098712 21252118 21317430 21577210 21614932 2191300 22331441 22514743 22652804 23140366 23338822 23390297 23784029 23869868 25374926 6357187 8515656 8871614 8893010 9312026 9389648 9618481 9670020
SMAD3 SMAD7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 10823886 15183844 12761881 10887185 10973944 10839991 10753944 10843994 15579469 10559222
SMAD7 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23331499 21071413 9892009 26555259 9892110
SMAD3 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 104.0 1.0 Omnipath 25609649 9843571 15084259 20211142 21532621 24584437 18729074 23788427 12419246 18923419 9892009 19768112 10531362 15231748 9679060 12167862 21988832 12150994 23331499 12543979 18568018 21071413 19135894 15467747 25502805 9732876 11927552 16189514 12917407 25514493 15350224 10995777 18988627 10092624 12732634 25910212 10878024 9111321 20564330 27107012 9311995 12957874 20142324 11114293 32296183 15588252 15761153 24157709 26555259 29892012 17469184 22442258 16714330 21597466 15922743 22045334 17591701 24382352 22310290 19139564 19917253 29997244 31515488 28115363 10942775 21297662 17283070 12794086
SMAD4 TBX21 â—¼   DOWN_REGULATES ✅ - 25.0 1.0 ACSN 10925299 11074002 11279127 11399519 11792802 11875494 12193690 12702545 12809600 15265520 15644117 16127449 16179589 16713975 17260466 17689680 18768831 21042762 21614932 22331441 23390297 6357187 8515656 8871614 9389648
SMAD4 SMAD7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 10823886 15183844 10887185 19032343 10839991 16442497 10753944 10843994 15128733 10559222
SYK SOS1 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 12456653 9341187 9705962 19372136 11071869 11449366 11909947 9697839 21822214
TYK2 STAT1 â—¼   ENZYMATIC_REACTION ✅ 16.0 1.0 ACSN 11207245 11698286 11964292 12811837 14610620 14764699 15864272 17513775 19833085 21115385 21840487 21930765 21930769 7512720 7521688 7543512
STAT1 TBX21 â—¼   ENZYMATIC_REACTION ✅ 46.0 1.0 ACSN 10485906 10754326 10820262 10952726 11134049 11399519 11830590 11875494 11964313 12193701 12223527 12433365 12796776 12811837 12907458 12967644 14607900 14607933 14660645 14764699 15465827 15644117 15699106 15814715 16127449 16878026 17016554 17260466 17404308 17485448 17513775 17559085 17689680 18272812 18345002 19833085 19879327 21097505 21263073 21930765 23390297 25960930 6357187 7594497 8683106 8871614
STAT1 TBX21 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17575072 18414429 16301649
TYK2 STAT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 68.0 1.0 Omnipath 11839738 10918587 15261459 8232552 7543024 15322115 23331499 8780896 10435617 24243840 11294897 7690989 14764663 18988627 12637327 11438544 10748192 14565860 7657660 12817007 23257612 29145629 9355737 11152457 23124025 18389480 10982844 7592750
SYK TUBA4A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 9490415 8617742