Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
PDIA3 ITGB5 â—¼   DISULFIDE_BOND ✅ 2.0 0.8 intact 17170699 5219449
LRRK2 DYRK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
ERO1A PDIA3 â—¼   DISULFIDE_BOND ✅ 2.0 0.8 intact 17170699 5219449
DDIT3 ERO1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19359519
PDIA4 ERO1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20802462 8075064
ERO1A P4HB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5212958 10970843
KNL1 PDIA3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
B2M THADA â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
B2M GYPC â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
B2M PDIA3 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
COL6A3 PDIA3 â—¼   DISULFIDE_BOND ✅ 2.0 0.8 intact 17170699 5219449
PDIA3 HIRIP3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PDIA3 ZGRF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PDIA3 FAM157B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
APP ADAM10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SP1 ADAM10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21854868
ADAM10 APP â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 20676056 10097139
PDIA3 ADAM10 â—¼   DISULFIDE_BOND ✅ 2.0 0.8 intact 17170699 5219449
ADAM17 PDIA3 â—¼   DISULFIDE_BOND ✅ 2.0 0.8 intact 17170699 5219449
SP1 ADAM17 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19772640
AGRN APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10673326 10339611
PDIA3 AGRN â—¼   DISULFIDE_BOND ✅ 2.0 0.8 intact 17170699 5219449
PDIA3 ANXA4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
LYN APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HSPA5 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HSPA8 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CAV1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CALR APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
OTUB1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ITGB1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CLU APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CAPN1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HMGB1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
APP GAPDH â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ATF2 DDIT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20102225 23661758
PDIA3 BRWD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
ITGB1 BRWD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
SERPINH1 CALR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
TAPBP CALR â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22153078 25083866
CALR HLA-A â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
CFTR CANX â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12208510 5215704
SOAT1 CANX â—¼   COLOCALIZATION 2.0 0.8 intact 8372609 22045338
PDIA3 CAPN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
STIM1 CAV1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0905002106 19897728
CAV1 STIM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0905002106 19897728
EP300 CBFB â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 24229708 15138260
PDIA3 CLU â—¼   DISULFIDE_BOND ✅ 2.0 0.8 intact 17170699 5219449
HSPA5 CNTRL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
SP1 COL1A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19558215
PDIA3 DIS3L2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PDIA3 DNAH14 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PDIA3 EFEMP1 â—¼   DISULFIDE_BOND ✅ 2.0 0.8 intact 17170699 5219449
PDIA3 ESCO1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
SP1 FGFR4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11981041 15475466
PDIA3 FILIP1L â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PDIA3 FRMD6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PDIA3 GALNTL5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PDIA3 GALR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
OTUB1 GRN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
P2RY6 GRN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ING4 GRN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PDIA3 HYDIN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PDIA3 ING4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
ITGA2 PDIA3 â—¼   DISULFIDE_BOND ✅ 2.0 0.8 intact 17170699 5219449
PDIA3 ITGA3 â—¼   DISULFIDE_BOND ✅ 2.0 0.8 intact 17170699 5219449
PDIA3 ITGA6 â—¼   DISULFIDE_BOND ✅ 2.0 0.8 intact 17170699 5219449
LAMB3 ITGA6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8143784 32196115
PDIA3 ITGB1 â—¼   DISULFIDE_BOND ✅ 2.0 0.8 intact 17170699 5219449
PDIA3 KITLG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
KITLG STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11071637 24116056
RARA LAMB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 2556699 8645318
LAMB1 PDIA3 â—¼   DISULFIDE_BOND ✅ 2.0 0.8 intact 17170699 5219449
LAMB3 PDIA3 â—¼   DISULFIDE_BOND ✅ 2.0 0.8 intact 17170699 5219449
SP1 LAMC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12034813 9403717
LAMC1 PDIA3 â—¼   DISULFIDE_BOND ✅ 2.0 0.8 intact 17170699 5219449
LAMC2 PDIA3 â—¼   DISULFIDE_BOND ✅ 2.0 0.8 intact 17170699 5219449
PDIA3 LDLR â—¼   DISULFIDE_BOND ✅ 2.0 0.8 intact 17170699 5219449
PDIA3 MND1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PDIA3 MRPL47 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
OTUB1 SOD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
P4HB PRDX4 â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 2.0 0.8 intact 8090267 21057456
PDIA3 PACSIN3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
SP1 PDHA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8476854
STIM1 PDIA3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8298334 21941299
SCN3A PDIA3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
SERPINH1 PDIA3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PDIA3 ZNF148 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PDIA3 THADA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PDIA3 ZNF101 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PDIA3 TEX14 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PDIA3 PPP1R21 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PDIA3 SEMA3C â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PDIA3 ZNF181 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PDIA3 SUPT20H â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
STIM1 PDIA3 â—¼   COLOCALIZATION 2.0 0.8 intact 8298334 21941299
PDIA3 STIM1 â—¼   PROXIMITY 2.0 0.8 intact 8298334 21941299
PRDX4 PDIA3 â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 2.0 0.8 intact 8090267 21057456
TAPBP PDIA3 â—¼   DISULFIDE_BOND ✅ 2.0 0.8 intact 17170699 5219449
PDIA4 PDIA3 â—¼   DISULFIDE_BOND ✅ 2.0 0.8 intact 17170699 5219449
PDIA3 PLOD1 â—¼   DISULFIDE_BOND ✅ 2.0 0.8 intact 17170699 5219449
PPIB PDIA4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
STIM1 PPIB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PPIB SERPINH1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PPIB PRKCSH â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PRKCZ VHL â—¼   COLOCALIZATION 2.0 0.8 intact 5219754 17350623
UBE3A RARA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
STAT3 SOX2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20132009 18447642
ITGA2 ITGB1 â—¼   PHYSICAL_INTERACTION 811.0 0.81 STRING 36370105
PDIA3 TPSN â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17170699 11823531
PDIA3 CLUS â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26496610 17170699
PRDX4 GRP78 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 32457219 33957083
GRP78 PPIB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22939629 33957083
GRP78 PDIA3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22939629 33957083
PDIA3 FBLN3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17170699 27777122
PDIA3 GTR1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 9153243
AGR2 PRDX4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31436131 30575818
AGR2 PDIA3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31436131 30575818
AGR2 PPIB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31436131 30575818
EP300 ATF2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24069158 10327051
BACE1 PDIA3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 15606899 20354142
BMI1 PPIB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 34316702 24457600
BMI1 PRDX4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 34316702 24457600
TAP1 CALR â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17055437 11823531
CALR PDIA4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24981860 34079125
CFTR CAV1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26618866 31324722
CFTR PPIB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31324722 17110338
CFTR LAMB3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26618866 31324722
CFTR PDIA3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26618866 31324722
HDAC6 EP300 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 15102857 19344692 12718889 22778253 23133622
EP300 PRDX4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21988832 33742100
PDIA3 JMJD8 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
MATN3 PDIA4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 16287128 23956175
APP CALR â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
CALR GANAB â—¼   PHYSICAL_INTERACTION 828.0 0.82 STRING 36370105
INHA CALR â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
INHA GRP78 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
INHA PDIA3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
PDIA3 ERO1A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 20802462 17170699
LDLR GRP78 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 10906332 16257961
FBLN3 GRP78 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 27777122
ANXA5 PDIA3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 27173435 24981860 26344197
DDIT3 ATF2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 23661758 20102225
HDAC6 CFTR â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 31501480 14675537 22069321
CFTR UBE3A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 19233847 17110338
HMGB1 PDIA3 â—¼   PHYSICAL_INTERACTION 833.0 0.83 STRING 36370105
EP300 VHL â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
MTOR STAT3 â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
ERO1L P4HB â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
SP1 STAT3 â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
MDM2 PPIB â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 24583282 29876924
B2M TAPBP â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
PLAA VCP â—¼   PHYSICAL_INTERACTION 0.84 0.84 HuRI 32296183
CFTR GRP78 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 26618866 29924966 22038833 17110338
CFTR PDIA4 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 26618866 29924966 31324722
PDIA3 STAT3 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 30612517 16189514 12060494
RARA UBE3A â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33995501 9891052 16713569
ERO1A PDIA4 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 20802462 34079125
PPIB CALR â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 24981860 30021884
APP CLU â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
LAMC1 LAMB1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 17517882
PDIA3 PDIA4 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 17170699 24981860 34079125
CFTR HSPA8 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
EP300 STAT3 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
EP300 MDM2 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
TAP1 TAPBP â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
APP BACE1 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
RARA BAG1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 9642262 16713569 16189514
CFTR GRN â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 26618866 29924966 17110338 31324722
SP1 EP300 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 10651903 34252870 16478997 11030335 11517158 15647279 17623675 17906698 28425985 32115405 31536933 12200149 24530506 23714681 10362258 22415975 16734381 19062177 10899165
HLA-A PDIA3 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
HSPA8 LRRK2 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
CALR TPSN â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 30021884 8769474 11823531
CANX VCP â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
RARA SP1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10361124 19401466 16713569 18270252
CFTR VCP â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
CALR P4HB â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
PDIA3 TAPBP â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
LAMB3 LAMC2 â—¼   CORRELATES + 0.89 0.89 CCLE 31978347
CANX B2M â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 14681859 2450918 10064069
TPSN TAP1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 12213826 11823531 11884415 17055437 18802093 19201886 16828748
SP1 ADAM17 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19772640 22705645
ADAM17 APP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9774383 12535668
APP GAPDH â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21832049 16713569 8473906
SP1 ATF2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 2145272 12760745
SP1 AXL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18522535 11953011 20977427
PDIA3 CALR â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 24981860 26344197 12052826 10436013 11823531 16189514 30021884
SMARCB1 CALR â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
HSPA8 CFTR â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 25961502 2799391 2204156
MDM2 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 9809062 11070080 16713569
EP300 HDAC6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15102857 19344692
HSPA8 HDAC6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 25961502 2799391 2204156
PRDX4 HDAC6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
LAMC1 ITGA3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11964076 16413178 16581764
LAMB1 ITGA3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11964076 16413178 16581764
ITGA3 LAMC2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11964076 16413178 16581764
ITGA3 LAMB3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11964076 16413178 16581764
LAMC2 ITGA3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10842354
LAMC1 ITGA6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11964076 16413178 16581764
LAMB1 ITGA6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11964076 16413178 16581764
ITGB1 LAMB1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11964076 16413178 16581764
ITGB1 LAMC1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11964076 16413178 16581764
LAMC2 ITGB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10842354
LAMB1 ITGB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10842354
KITLG STAT3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11494148 10358045 9355737
PDIA4 PPIB â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 34079125 24981860 22665516 30021884
RARA RPTOR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21060808
ITGA6 ITGB1 â—¼   PHYSICAL_INTERACTION 911.0 0.91 STRING 36370105
TAP1 TAPBP â—¼   CORRELATES + 0.91 0.91 CCLE 31978347
B2M CALR â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
EP300 SP1 â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
PBRM1 SMARCB1 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
HLA-B B2M â—¼   PHYSICAL_INTERACTION ✅ 0.92 0.92 mint 8624811 5220994
CALR TAPBP â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
CANX GANAB â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
HLA-A TAPBP â—¼   PHYSICAL_INTERACTION 967.0 0.96 STRING 36370105
RICTOR MTOR â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 24036451
MTOR RICTOR â—¼   COLOCALIZATION ✅ 0.97 0.97 mint 21045808 8088164
GANAB PRKCSH â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
LAMB1 LAMC1 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
RPTOR MTOR â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 24036451
MTOR RPTOR â—¼   COLOCALIZATION ✅ 0.98 0.98 mint 21045808 8088164
B2M HLA-B â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
B2M HLA-A â—¼   PHYSICAL_INTERACTION 989.0 0.98 STRING 36370105
BAG1 HSPA8 â—¼   PHYSICAL_INTERACTION 989.0 0.98 STRING 36370105
MTOR RPTOR â—¼   PHOSPHORYLATION ✅ + 0.98 0.98 Signor 19346248
SP1 ITGB5 â—¼   ENZYMATIC_REACTION ✅ 8.0 1.0 ACSN 10964912 11007770 11013220 15001984 17705132 18353785 21252118 23338822
ITGB5 ITGA2 â—¼   DOWN_REGULATES ✅ - 5.0 1.0 ACSN 22470492 24309651 26519775 9295024 9763615
PDIA3 B2M â—¼   ENZYMATIC_REACTION ✅ 8.0 1.0 ACSN 14508489 16181333 16239148 17204652 20958319 22076556 23157435 23850759
CALR B2M â—¼   ENZYMATIC_REACTION ✅ 8.0 1.0 ACSN 14508489 16181333 16239148 17204652 20958319 22076556 23157435 23850759
ADAM10 ADAM17 â—¼   PHYSICAL_INTERACTION 5.0 1.0 ACSN 18676862 19601831 19704010 19726682 22006996
ADAM10 APP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 32814053 30538620 12535668
ADAM17 ITGB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 22413019 14970227 30455686
SP1 APP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 19049493 8427604 15673661 9361293 21557719 18449948 14701757 8015372
BACE1 APP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 30538620 22801501 10677483 20418918 12901838 10531052 10931940 32814053 28923680 28869759 19251705
MAPK13 ATF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 15187187 19436832 9207191 10581204 15140942 20506250 21614932 19135240 16393692 12244047 11274345
BAG1 HSPA8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 25535373 26871637 9305631 11222862 10671488 14978028 17954934 20675402 25416956 9873016 19800331 16189514 9774640 12874020 11741305 12297498 27474739
CALR PDIA3 â—¼   PHYSICAL_INTERACTION 8.0 1.0 ACSN 14508489 16181333 16239148 17204652 20958319 22076556 23157435 23850759
SP1 CAV1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15531587 10684646 23280667 21631282 17108117
HSPA8 CFTR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 21148293 10666020 19878303 21697503
SP1 COL1A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 10091149 16575855 9666093 10775443 12138160 11348466 17698844 16564026 10082137 7504695 7590335
COL1A1 P4HB â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 4.0 1.0 Reactome 2543975 16591531 1323838 14500733
COL1A1 ITGB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 7716514 10464311 7688313
COL1A1 ITGA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 11359786 7688313 11856343 2156854
DDIT3 HSPA5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23667408 22905241 10218478 22802018 10472808 20801537
MAPK13 DDIT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15187187 19436832 15140942 20506250 21614932 16393692 11274345
EP300 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 18782771 15509516 8756628 10205054 7530500 15653507 15735682 19506034 16285960 16713569 11322950 7499365 15649887 9590694
FGFR4 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 54.0 1.0 Omnipath 19901323 10918587 9305919 8272872 12626508 16497976 15592455 17389395 12576423 11350938 11294897 12244095 9083098 8626374 9566874 11940572 11429593 14551213 11850821 17016520 9582023
SP1 ITGA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8887648 20090957 11238113 11313353
LAMC2 ITGA6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10842354 8143784
LAMB1 ITGA6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 7721947 11733063 10842354
LAMC1 ITGA6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 7721947 10671376 11733063 32196115
ITGB1 LYN â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 ACSN 12626562 19161977 19454690 19487819 22470492 9003039 9456329 9763606 9973479
SP1 LDLR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 24358207 14568562 7836375 11250935 10894816 9610768 11792717 16647292 7597088 14998783 7627719 10841543 16303770 9271397 10224053 16449644
MTOR RPTOR â—¼   PHYSICAL_INTERACTION 72.0 1.0 ACSN 10702316 11108711 11274345 11756498 12150925 12408816 12533512 12709531 12713446 12844354 12867079 12906785 15314020 15749884 15755954 15905173 16286006 16469695 16679021 16713974 16915281 17052453 17053147 17368478 17404308 17604271 17680028 18000759 18046414 18048642 18372248 18391071 18423201 18492954 19022819 19143636 19151919 19225151 19244117 19339977 19446321 19568798 19597330 19706736 19720745 19864431 19930715 20138985 20547845 20647036 20805416 20832730 20932932 21157483 21177869 21233202 21474067 21981924 22504639 23087689 24795729 24973821 25002027 25682865 25730849 26159692 26597054 27328425 27331412 27510662 27572739 28216025
MTOR RICTOR â—¼   PHYSICAL_INTERACTION 41.0 1.0 ACSN 10722653 11274345 11756498 12408816 12906785 16469695 16556040 16678438 17461779 17680028 18000759 18481918 18492954 18566586 18570873 18925875 19022819 19027299 19143635 19151919 19446321 19568798 19706736 19720745 20027184 20338997 21157483 21474067 21533173 21621563 21708191 21981924 23087689 24795729 24973821 25002027 25730849 26159692 27331412 28216025 9069260
MTOR RICTOR â—¼   SHARES_COMPLEX 41.0 1.0 ACSN 10722653 11274345 11756498 12408816 12906785 16469695 16556040 16678438 17461779 17680028 18000759 18481918 18492954 18566586 18570873 18925875 19022819 19027299 19143635 19151919 19446321 19568798 19706736 19720745 20027184 20338997 21157483 21474067 21533173 21621563 21708191 21981924 23087689 24795729 24973821 25002027 25730849 26159692 27331412 28216025 9069260
MTOR RPTOR â—¼   SHARES_COMPLEX 72.0 1.0 ACSN 10702316 11108711 11274345 11756498 12150925 12408816 12533512 12709531 12713446 12844354 12867079 12906785 15314020 15749884 15755954 15905173 16286006 16469695 16679021 16713974 16915281 17052453 17053147 17368478 17404308 17604271 17680028 18000759 18046414 18048642 18372248 18391071 18423201 18492954 19022819 19143636 19151919 19225151 19244117 19339977 19446321 19568798 19597330 19706736 19720745 19864431 19930715 20138985 20547845 20647036 20805416 20832730 20932932 21157483 21177869 21233202 21474067 21981924 22504639 23087689 24795729 24973821 25002027 25682865 25730849 26159692 26597054 27328425 27331412 27510662 27572739 28216025
MTOR RPTOR â—¼   ENZYMATIC_REACTION ✅ 72.0 1.0 ACSN 10702316 11108711 11274345 11756498 12150925 12408816 12533512 12709531 12713446 12844354 12867079 12906785 15314020 15749884 15755954 15905173 16286006 16469695 16679021 16713974 16915281 17052453 17053147 17368478 17404308 17604271 17680028 18000759 18046414 18048642 18372248 18391071 18423201 18492954 19022819 19143636 19151919 19225151 19244117 19339977 19446321 19568798 19597330 19706736 19720745 19864431 19930715 20138985 20547845 20647036 20805416 20832730 20932932 21157483 21177869 21233202 21474067 21981924 22504639 23087689 24795729 24973821 25002027 25682865 25730849 26159692 26597054 27328425 27331412 27510662 27572739 28216025
MTOR RPTOR â—¼   LOCALISATION ✅ 72.0 1.0 ACSN 10702316 11108711 11274345 11756498 12150925 12408816 12533512 12709531 12713446 12844354 12867079 12906785 15314020 15749884 15755954 15905173 16286006 16469695 16679021 16713974 16915281 17052453 17053147 17368478 17404308 17604271 17680028 18000759 18046414 18048642 18372248 18391071 18423201 18492954 19022819 19143636 19151919 19225151 19244117 19339977 19446321 19568798 19597330 19706736 19720745 19864431 19930715 20138985 20547845 20647036 20805416 20832730 20932932 21157483 21177869 21233202 21474067 21981924 22504639 23087689 24795729 24973821 25002027 25682865 25730849 26159692 26597054 27328425 27331412 27510662 27572739 28216025
RPTOR MTOR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 139.0 1.0 Omnipath 15268862 24403073 20427287 22258093 21321085 19446321 15467718 19875983 17461779 12665511 12719976 16631613 21045808 21177249 23911927 24337580 25446900 24516643 18614546 12718876 12747827 16603397 17043309 18519641 22544753 25007995 27043084 19145465 23953116 19619545 16919458 24375676 15459249 16837165 16847060 25332233 12150926 22424946 26348909 12150925 18955708 20381137 22356909 17386266 17565979 18030348 16354680 20169205 19114562 21071439 27329724 35561222 16798736 15809305 22493283 17277771 15661536 16962653 1683716516603397 17604271 18676370 16183647 18505677 23297343 23872070 24036451 15066126 18570873 21614075 18722121 12408816 17599906
MTOR STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 29228628 10660304 22408571 12796477 16740698 18691976 26573296 15522880 27384580 26775702 24423131 26241748 23055980
PDIA3 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12060494 16375900 16189514 30612517
PRKCZ SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 23148884 16943418 18258854 19464346 27320013 17049555 20953893
SP1 RARA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16740727 7585542 15831516 9626663
SP1 SOD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 8921911 18586551 18608091 21056687 24946209 11724400 9867871