Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list
Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins
Filter Graph:

0.5
Layout:
  🔂

Click a node or edge for more data...
Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
NUP42 TAP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7033698 19165146
KAT7 POLB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
HLA-C B2M â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5211709 10429675
B2M PDIA3 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
JUND TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9826775 9030359
CREB3 SEC22B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
TAPBP SEC22B â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22153078 25083866
SEC22B TAP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22153078 25083866
SEC22B TAP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22153078 25083866
SEC22B CALR â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22153078 25083866
TAPBP CALR â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22153078 25083866
CALR TAP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22153078 25083866
CALR HLA-A â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
PDIA2 CALR â—¼   COLOCALIZATION 2.0 0.8 intact 23167757 8401719
IRF1 CD40 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18694960
TP53 CDC42 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
CHRM3 TAP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
TAP1 CREB3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
CREB3 EMD â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
TP53 DDB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11971958
TP53 DLST â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17916908 21191025
IRF1 HLA-A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19428110
TP53 HLA-A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15501971 12857899
STAT1 HLA-A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9396771 19439556
IRF1 PSMB10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18694960
IRF2 TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9625761 18802049
IRF2 TAP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15778351
STAT1 IRF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15778351
KAT7 TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16547255 17532302
KRTAP4-12 TAP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
TAP1 MDFI â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
NFKB1 PSMB9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18694960
NFKB1 TAP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18694960
NFKB1 TAPBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18694960
P4HB PDIA2 â—¼   COLOCALIZATION 2.0 0.8 intact 23167757 8401719
TAPBP PDIA3 â—¼   DISULFIDE_BOND ✅ 2.0 0.8 intact 17170699 5219449
TP53 TAP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
DDB2 TAP1 â—¼   KO_UP_REGULATES ✅ + 0.8 0.8 PKG 28854368
MUL1 TP53 â—¼   PHYSICAL_INTERACTION 818.0 0.81 STRING 36370105
PDIA3 TPSN â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17170699 11823531
TAP1 1A01 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 11884415 17055437
GRPR TAP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
TAP1 CALR â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17055437 11823531
CDC42 VAPA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 26344197
TAP2 HLAG â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 9103419 16189514
TAP1 HLAG â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 9103419 16189514
GEMIN4 TAP1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HuRI 32296183
TPSN 1A01 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 11884415 8769474
B2M TAPBP â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
LCE2C TAP1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HuRI 32296183
TAP1 B2MG â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 18802093 17055437
TAP1 TAPBP â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
IRF1 STAT1 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
STAT1 IRF1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 16512786 10764778
TAP2 TAPBP â—¼   CORRELATES + 0.88 0.88 CCLE 31978347
CDX2 KRTAP4-12 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
HLA-A PDIA3 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
TPSN TAP2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 12213826 19201886 16828748
CALR TPSN â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 30021884 8769474 11823531
1A01 B2MG â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 11502003 1448153 16189514 27649529 8805302
HLAG B2MG â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 9228302 17056715 18332182 12853576 16189514
CALR P4HB â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
PDIA3 TAPBP â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
CDX2 CDX1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 23382958 11997022 19725873
CANX B2M â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 14681859 2450918 10064069
NFKB1 B2M â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12480693 2196446
TPSN TAP1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 12213826 11823531 11884415 17055437 18802093 19201886 16828748
PDIA3 CALR â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 24981860 26344197 12052826 10436013 11823531 16189514 30021884
NFKB1 CDX2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20303354 12360479 16618413
HLA-C IFNG â—¼   DOWN_REGULATES ✅ - 3.0 0.9 ACSN 11513144 21339333 9605119
IFNG STAT1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 12040185 7796299 8156998
IRF1 TAP2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18694960 11238639
STAT1 ISG15 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16009940 17312100
STAT1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24655378 14602726
TAP1 TAPBP â—¼   CORRELATES + 0.91 0.91 CCLE 31978347
B2M CALR â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
HLA-B B2M â—¼   PHYSICAL_INTERACTION ✅ 0.92 0.92 mint 8624811 5220994
CALR TAPBP â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
TP53 JUND â—¼   KO_DOWN_REGULATES ✅ - -0.93 0.92 PKG 28854368
COPB1 COPG1 â—¼   CORRELATES + 0.93 0.93 CCLE 31978347
KRTAP4-12 LCE2C â—¼   PHYSICAL_INTERACTION 0.94 0.94 HuRI 32296183
PSMB10 PSMB8 â—¼   PHYSICAL_INTERACTION 949.0 0.94 STRING 36370105
COPB1 COPG1 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
TAP1 TAP2 â—¼   CORRELATES + 0.95 0.95 CCLE 31978347
PSMB10 PSMB9 â—¼   PHYSICAL_INTERACTION 964.0 0.96 STRING 36370105
HLA-A TAPBP â—¼   PHYSICAL_INTERACTION 967.0 0.96 STRING 36370105
TAP1 TAP2 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
PSMB8 PSMB9 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
B2M HLA-G â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
B2M HLA-C â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
B2M HLA-B â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
B2M HLA-A â—¼   PHYSICAL_INTERACTION 989.0 0.98 STRING 36370105
PDIA3 B2M â—¼   ENZYMATIC_REACTION ✅ 8.0 1.0 ACSN 14508489 16181333 16239148 17204652 20958319 22076556 23157435 23850759
CALR B2M â—¼   ENZYMATIC_REACTION ✅ 8.0 1.0 ACSN 14508489 16181333 16239148 17204652 20958319 22076556 23157435 23850759
CALR PDIA3 â—¼   PHYSICAL_INTERACTION 8.0 1.0 ACSN 14508489 16181333 16239148 17204652 20958319 22076556 23157435 23850759
STAT1 CD40 â—¼   ENZYMATIC_REACTION ✅ 46.0 1.0 ACSN 10485906 10754326 10820262 10952726 11134049 11399519 11830590 11875494 11964313 12193701 12223527 12433365 12796776 12811837 12907458 12967644 14607900 14607933 14660645 14764699 15465827 15644117 15699106 15814715 16127449 16878026 17016554 17260466 17404308 17485448 17513775 17559085 17689680 18272812 18345002 19833085 19879327 21097505 21263073 21930765 23390297 25960930 6357187 7594497 8683106 8871614
STAT1 CD40 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 20006573 10403401 17660512 10823830 16020513 17507688 15182726 16571771
NFKB1 CD40 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17513725 11313274 19164127 11027342 17031478 9733827
TP53 DDB2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 12771027 22336944 15856024 12509284 12170778 16357511 12967652 15927209 11971958
HLA-G IFNG â—¼   ENZYMATIC_REACTION ✅ 19.0 1.0 ACSN 10925299 11438547 11489965 11513144 11875494 11994457 12055234 12811837 15081523 15778339 16287995 16713974 17100877 20435894 23414611 23508573 24378531 9625766 9751747
IRF1 HLA-G â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19758196 11087747
IFNG STAT1 â—¼   ENZYMATIC_REACTION ✅ 69.0 1.0 ACSN 10485906 10754326 10820262 10952726 11134049 11399519 11489965 11579131 11777960 11830590 11870632 11875494 11964313 12193701 12223527 12413632 12433365 12796776 12811837 12818165 12907458 12967644 14607900 14607933 14660645 14764699 15465827 15634932 15644117 15699106 15778339 15811952 15814715 16127449 16286920 16424049 16713974 16878026 17016554 17260466 17404308 17485448 17513775 17559085 17689680 1825141 18272812 18345002 19833085 19879327 20038811 20819927 21097505 21149606 21263073 21411734 21930765 23390297 24658051 25960930 26755705 2965306 6357187 6425450 7594497 8683106 8871614 9834059 9864217
IFNG STAT1 â—¼   DOWN_REGULATES ✅ - 69.0 1.0 ACSN 10485906 10754326 10820262 10952726 11134049 11399519 11489965 11579131 11777960 11830590 11870632 11875494 11964313 12193701 12223527 12413632 12433365 12796776 12811837 12818165 12907458 12967644 14607900 14607933 14660645 14764699 15465827 15634932 15644117 15699106 15778339 15811952 15814715 16127449 16286920 16424049 16713974 16878026 17016554 17260466 17404308 17485448 17513775 17559085 17689680 1825141 18272812 18345002 19833085 19879327 20038811 20819927 21097505 21149606 21263073 21411734 21930765 23390297 24658051 25960930 26755705 2965306 6357187 6425450 7594497 8683106 8871614 9834059 9864217
IRF2 IFNG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12479817 18281489 10859338 10454342
STAT1 IFNG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 70.0 1.0 Omnipath 12759422 14735146 26170288 8823363 1833631 8647290 7619083 11416037 12130529 16162660 21178011 9218597 12493643 17283162 15217838 10830295 24200694 7957928 19476491 9271410 19262492 7565811 9880553 17878383 9748323 21039465 17016440 10881178 21530491 17270146 12052885 15055356 10201928 18616672 13678429 19124156 9491997 24478085 8509377 8990168 12893768 16380218 23740952 17105733 16195385 23419754 19935876 7796811 17558024 19929594 10713330 23645984 9548487 11390994 12223098 15931263 17689680 18802113 18787082 10440232 20004484 10373559 10585866 10707961 12403783 23582260 10982806 9059994 16785492 22767256
NFKB1 IFNG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 12759422 21642544 21243522 9374532 10227974 16481345 17556653 19732956 21224476 14662860 12757742 18690006 17407192
IFNG STAT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 29796172 23285134 18566411 28430601 28143527 24366643 24608040 17947699 25950470 19846878 27378243 18950705 27570112 15051500 17986321 26467650 23657944 20087684 9649436 22823229 14517275 22178447 22425562 23352233 23562842 28445952 11960596 17997851 24443556 26934444 24777831 11972023 12725866 26113305 22162832 29925830 10707961 23840250 25753288 9454765
TNF IRF1 â—¼   ENZYMATIC_REACTION ✅ 49.0 1.0 ACSN 10820262 10925299 11112697 11274345 11280761 11438547 11460167 11875494 12433365 12646658 12811837 1431106 14607933 14625680 14660645 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18345002 18633355 18641653 19392652 19411070 20038811 20184663 20435894 21133840 21232017 21411734 21826665 22955274 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 8910423
STAT1 IRF1 â—¼   ENZYMATIC_REACTION ✅ 46.0 1.0 ACSN 10485906 10754326 10820262 10952726 11134049 11399519 11830590 11875494 11964313 12193701 12223527 12433365 12796776 12811837 12907458 12967644 14607900 14607933 14660645 14764699 15465827 15644117 15699106 15814715 16127449 16878026 17016554 17260466 17404308 17485448 17513775 17559085 17689680 18272812 18345002 19833085 19879327 21097505 21263073 21930765 23390297 25960930 6357187 7594497 8683106 8871614
TP53 IRF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15509808 9806359 12732645 11350897
STAT1 IRF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 10528163 9218597 10068671 18694960 11752148 17270146 12077266 20825659 24478085 11694349 9307237 8621447 18401423 9806359 22002246 10764778 16140971 19122651 18497060 7678055 8647845 10666420 8168491 9259325 21200019 17558387
NFKB1 IRF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12077266 18694960 17274000 12595462
IRF1 TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 18802049 17725714 23811275 24012417 19805480 10404391 12165487 16931033 26206900
IRF1 TAP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18694960 14735146 9632673 8885869 15778351
IRF1 PSMB9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 18694960 14735146 16512786 9632673 10921891 16703666 10764778 8885869
IRF1 IRF2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 7630638 7507207 9054665 8152803 15560761 10321737 12493643 1431317
STAT1 IRF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 24012417 16512786 10764778 17918184
STAT1 IRF2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22951020
NFKB1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10348347 11032029 8051093 12145335 20097177
NFKB1 TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 74.0 1.0 Omnipath 17513725 12058956 24337575 12657243 17704137 12471036 17707233 7624137 11259437 12686724 16433741 26114754 20237317 7876168 16707469 12117498 14976218 10485496 15465827 8622636 15812247 21138578 18990758 10748079 15013838 15749903 16916598 17646159 10754326 16040075 10837498 18285351 11675405 11739517 15743782 20066113 20617556 17085785 8530146 8805669 10919279 14960579 1740105 10963848 16055086 9742085 17292554 10553096 11312646 15543947 17442180 16285952 10079106 11297551 10551799 10201927 12907458 8679226 9281604 22782967 8219230 11749970 9916895 11094063 11490006 7895918 1618817 16483936 18057724 20722069 16569682 9452482 17407192 17082635
STAT1 PSMB9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 14735146 19122651 16512786 9632673 10921891 16703666 10764778
STAT1 TNF â—¼   ENZYMATIC_REACTION ✅ 46.0 1.0 ACSN 10485906 10754326 10820262 10952726 11134049 11399519 11830590 11875494 11964313 12193701 12223527 12433365 12796776 12811837 12907458 12967644 14607900 14607933 14660645 14764699 15465827 15644117 15699106 15814715 16127449 16878026 17016554 17260466 17404308 17485448 17513775 17559085 17689680 18272812 18345002 19833085 19879327 21097505 21263073 21930765 23390297 25960930 6357187 7594497 8683106 8871614
STAT1 TAP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 14735146 9632673 10975834 15240699 15778351
TAP2 TAP1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 ACSN 10973281 11717192 14508489 16181333 17204652 22076556 22790179
TAP2 TAP1 â—¼   SHARES_COMPLEX 7.0 1.0 ACSN 10973281 11717192 14508489 16181333 17204652 22076556 22790179
POLB CD40 â—¼   KO_DOWN_REGULATES ✅ - -1.04 1.03 PKG 28854368
POLB TAP1 â—¼   KO_DOWN_REGULATES ✅ - -1.57 1.56 PKG 28854368
TDP2 TDP2 â—¼   KO_DOWN_REGULATES ✅ - -2.0 1.99 PKG 28854368
TP53 DDB2 â—¼   KO_DOWN_REGULATES ✅ - -3.51 3.5 PKG 28854368
DDB2 DDB2 â—¼   KO_DOWN_REGULATES ✅ - -5.71 5.7 PKG 28854368
POLB POLB â—¼   KO_DOWN_REGULATES ✅ - -7.24 7.23 PKG 28854368