Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
TCF7L2 BCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17404573 23671559
NR0B2 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18537191 12571228
EP300 VDR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21988832 20089040
CTNNB1 PARP2 â—¼   ADP_RIBOSYLATION ✅ 2.0 0.8 intact 8201796 21812934
CDX1 ZMPSTE24 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
SOX2 CDX2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20384793 22902753
TCF7L2 CDX2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17468517 18655789
CDX2 CDX4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20933081
CDX1 PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19059241
NR0B2 INS â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 21817852 17259388
VDR CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11470825 23331499
CTNNB1 SOX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 24291232 24482235
CDX1 DDX42 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
TCF7 LEF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 32448362 25921273
LEF1 VDR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17517646 0702884104
LEF1 CDX1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15143193
NR0B2 THRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 11368516
FOXA2 TCF7L2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22951069
TCF7L2 TCF7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15473860 10489374
VDR CALB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 1317496
CDX1 MUC2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12559945 14525978
ELAV2 CLK2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CDX1 CLK2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CLK2 CASC3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CDX1 DHX30 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
SOX2 DHX30 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 35140242 21280222
CDX1 PARP2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CDX1 RBBP6 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CDX1 CASC3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
ELAV2 CASC3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CDX1 TRUB2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CDX1 CDK12 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CDX1 HIRA â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CDX1 ASH1L â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
ELAV2 RENT1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
F120A RENT1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 29395067 33961781
CDX1 RENT1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CDX1 CABIN â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
ELAV2 YTDC1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CDX1 YTDC1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CDX1 PUM2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
ELAV2 PUM2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CDX1 KBTB7 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CDX1 ELAV2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
ELAV2 F120A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
ELAV2 ZCHC3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
ELAV2 ZFR â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
ELAV2 LAR1B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CDX1 KBTB6 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CDX1 SREK1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CDX1 RBM23 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CDX1 RT09 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CDX1 RL26L â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CDX1 UBN2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CDX1 LIN41 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CDX1 ZN107 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CDX1 PTCD1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CDX1 ANR17 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CDX1 TUT7 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CDX1 PEO1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CDX1 ZCHC3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CDX1 NOG2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CDX1 MTER1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CDX1 NGRN â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CDX1 ZFR â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CDX1 LAR1B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CDX1 ZN121 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CDX1 F120A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CDX1 ANKH1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CDX1 TBA8 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CDX1 ZN431 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CDX1 RBM19 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CDX1 RL36L â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CDX1 DHX29 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
F120A ZCHC3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 29395067 33961781
HOXB4 HOXB7 â—¼   PHYSICAL_INTERACTION 820.0 0.82 STRING 36370105
NGRN TRUB2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 27667664 33961781 32877691
UBN2 HIRA â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 33961781 24981860 19029251
KBTB7 KBTB6 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 25684205 20562859 26496610 33961781 33990333
RBM23 ANKH1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
EP300 PCNA â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
CCND1 EP300 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
CTNNB1 PPARG â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
CTNNB1 TCF7 â—¼   PHYSICAL_INTERACTION 858.0 0.85 STRING 36370105
SOX2 RT09 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 35140242 23667531
CLK2 RBBP6 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 32460013 23602568
CLK2 YTDC1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 32296183 25416956 33961781
TRUB2 MTER1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 27499296 33961781 32877691
EP300 PPARG â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
EP300 CCND1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 15951563 10567390 11788592
EP300 VDR â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 32603375 15647825 20089040 21988832
NR0B2 PPARG â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11696534 16189514 19596656
CTNNB1 BCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17404573 16288908 12782598
TCF7 BCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17404573 16288908 12782598
PCNA CCND1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15681588 7908906 8101826 33961781 7903056 21654808
SOX2 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18456656 25482558
CDX1 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15215241 14508520 10660624
EP300 PCNA â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11268218 16713569 18263614 12937166 24939902 14988403 33742100
EP300 PPARG â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11500849 17468099 10944516 14701856 11287611 19596656 32603375 11877444 12040021 10075656 30595551 22787115 12479814
PPARG PCNA â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17389773 14764597 19673929
RENT1 CASC3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19478851 22522823 18066079
CDX2 DSC2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18819935
CDX2 CDX1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 23382958 11997022 19725873
CDX2 INS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16002547 7698771 12783165
NR0B2 PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 24038081 16803864 11696534
FOXA2 CEBPA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19074951
MAFB INS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16780794 18199433 17360442
CTNNB1 TCF7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15473860 17724465 10489374
TCF7 LEF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15473860 17335794 11326276
FOXA2 IAPP â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 24627476 15566941 11875061
CDX1 DSC2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18819935
CTNNB1 EP300 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
CTNNB1 APC â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 36950384
TCF7L2 CTNNB1 â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 11713475 5214798
BCL9 CTNNB1 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
CTNNB1 LEF1 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
CTNNB1 TCF7L2 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
APC CTNNB1 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
APC BCL9 â—¼   PHYSICAL_INTERACTION 33.0 1.0 ACSN 11274345 11955436 11967263 12051714 12711682 15001769 15327769 15834423 16039586 16510874 16547505 16940750 17143292 17439715 17936032 19216735 19506021 19619488 19623618 19751508 20006983 20705860 20964627 21285352 21681822 22270359 23343194 24023259 25730849 26587781 7542250 8545107 8666229
APC BCL9 â—¼   SHARES_COMPLEX 33.0 1.0 ACSN 11274345 11955436 11967263 12051714 12711682 15001769 15327769 15834423 16039586 16510874 16547505 16940750 17143292 17439715 17936032 19216735 19506021 19619488 19623618 19751508 20006983 20705860 20964627 21285352 21681822 22270359 23343194 24023259 25730849 26587781 7542250 8545107 8666229
APC CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 60.0 1.0 Omnipath 17145710 10545404 11166179 8259519 7890674 22083140 27902311 8638126 16212417 16798748 19061640 9286858 15327769 9482734 11533658 22056988 19576224 15327768 17318191 26496610 12628243 15355978 9065403 11712088 25241761 26910375 22682247 9065401 12000790 11707392 20219694 9707618 23840886 15525529 11251183 8628279 19631635 11972058 21664290
CEBPA BCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 16254192 18987666 23814099 15713621 12970736
PPARG BCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15067355 14960510 15878253 19956851 15094967
TCF7L2 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 17108104 17360646 17468517 15026412 12235165 15126340 22005519 22318732
LEF1 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 17360796 10318916 17666529 19620402 19653274 12748295 15798764 17885813
PPARG CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 23455892 18927468 14764597 15486348 11287611 20651819 15041706 19075513 15193259
CTNNB1 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 16628468 10318916 12095419 15111320 15735151 18679417 17360646 12782598 10201372 14557550 19778454 20300972 19662654 12589056 11943708 10915780 17693601 15592430 17109766
EP300 CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 17306568 17666529 11788592 23343194 21285352 15576399 21151179 22761862 22290435 16039586 19619488 19623618 17143292
TCF7L2 CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 17666529 23343194 21285352 18974774 22761862 22290435 16039586 19619488 19623618 17143292
TCF7 CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 17666529 23343194 21285352 18974774 22761862 22290435 16039586 19619488 19623618 17143292
CTNNB1 CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 29.0 1.0 Omnipath 19751508 10318916 7542250 11967263 22290435 11836555 19623618 12663502 23343194 11955436 22270359 22761862 16039586 15810077 10201372 19020303 17143292 12051714 17208333 8666229 18974774 16940750 14712077 17666529 21285352 19619488 15377999
LEF1 CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 19751508 10318916 7542250 11967263 22290435 19623618 12663502 23343194 11955436 22270359 22761862 16039586 15810077 10201372 19020303 17143292 12051714 8666229 18974774 16940750 14712077 17666529 21285352 19619488 15377999
PCNA EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 18263614 11268218 16713569
EP300 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 11050151 18987336 15806138 15060161 17410209
CDX2 MUC2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 12559945 14525978 16118348
CDX2 SI â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 10889158 11283019 18005670 12060663 16480684 17466947 11408257 16574312 9679043 20133952
CEBPA PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 22553076 20725087 15664998 15110775 18619497 19059241 9367890 15158467 23071089 10862621 15632071 16580992
PPARG CTNNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 12021175 15190077 20303941 14764597 19075513
CTNNB1 PPARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 25721714 16847334 25168821 19495794
BCL9 LEF1 â—¼   PHYSICAL_INTERACTION 20.0 1.0 Reactome 12163411 16169192 11955446 18347063 17458864 22186018 15294866 16005293 16510874 19487454 9490669 17425782 19493659 18498752 17052462 22190459 18404694 11988739 17428831 22617422
BCL9 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 17145710 15294866 23331499 11955446 17052462 15371335 24360964 15208637
FOXA2 INS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17471492 15790780 18847435 15123725
TCF7L2 CTNNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 24214913 14706452 19347947 24317174
CTNNB1 LEF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17785445 15473860 11326276 17335794 15728254
CTNNB1 CDX1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10934025 11997022 12242722 12446687
WNT2 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 29.0 1.0 Omnipath 7641885 15265686 19718039 21602792 210606194 8655584 19705439 19029934 20093472 17430994 21606194 17884187 14747478 22017973 22433869 17143292 20006983 19072724 14704854 16965538 16443747 22007144 16547521 19020754 20940130 21640127 21087212 17127310 21796133
CTNNB1 LEF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 50.0 1.0 Omnipath 16510874 23151663 11751639 15735151 17143293 16204248 23331499 12556497 21071413 14638683 15768032 18296023 12748295 21743491 11835406 16510875 18077326 8757136 9065403 20123964 15728254 17517646 21078818 15684397 8892228 10890911 15525529 12077367 9419974
CTNNB1 TCF7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 25678599 19358846 16442529 15735151 17143293 9065401
CTNNB1 TCF7L2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 54.0 1.0 Omnipath 17145710 9488439 11713475 12446687 17143293 27902311 16569639 22014570 16724116 11955446 16442529 26350900 19202075 17050667 20126258 22056988 16306047 17914096 19443654 18391971 21670201 22155184 10080941 17283121 16230076 22304967 16630820 15684397 11713476 12861022 19304756 20492721 19816403 18772112
TCF7L2 LEF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15473860 20802155 17335794 11326276
LEF1 CDX1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15143193 10934025 11997022 12446687