Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
H1-0 H1-5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H1-0 CDK2 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 0805009105 18719096
HMGA2 H1-5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
HMGA1 H1-5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H1-5 HIRA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H3F3A H3F3B â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
H3C2 NASP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
H3C2 RBBP7 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17344414 17210787
H3C2 RBBP4 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17344414 17210787
H3-3B RBBP4 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17344414 17210787
H3-3B RBBP7 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17344414 17210787
RPA2 CDK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10882098 10757793
CHAF1A CDK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218806 16826239
PML ELF4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14976184
ESR1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 3677090
ESR1 HSPA8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11085516
PPIB HIRA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
HMGA1 SOX6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
HNF4A TCF7L2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22951069
TCF7L2 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath
JUN TP53BP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8910340 9448005
PML JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9671405 10620019
MYC TFAP4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19270520
MYC SMARCA4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24285714 24362264
RPA1 UBE2I â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 24782567 20705237
UBE2I RUVBL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18087039 0710343105
UBE2I TP53BP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22661230 22635276
CABIN1 MEF2D â—¼   DOWN_REGULATES ✅ - 0.8 0.8 Signor 17172641
ASF1B HAT1 â—¼   PHYSICAL_INTERACTION 804.0 0.8 STRING 36370105
CDX1 HIRA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CDX1 UBN2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ESR1 H31 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 23403292 31527615
RBBP7 H33 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 27705803
MYC H33 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21150319 32140074
ZBT48 HIRA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
JUN APEX1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25609649 34079125
ESR1 APEX1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31527615 19805454
NASP HAT1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26496610 24981860
TEAD2 HIRA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
MECP2 HIRA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SP4 HIRA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
TFAP4 HIRA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
MYC JUN â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21150319 20232342
MYC RBBP4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
TEAD2 UBN2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
TFAP4 UBN2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
H3F3B NASP â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
CHAF1B RBBP4 â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
HIST2H3C TP53BP1 â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
NASP RBBP7 â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
ASF1A HAT1 â—¼   PHYSICAL_INTERACTION 825.0 0.82 STRING 36370105
HIST1H4F NASP â—¼   PHYSICAL_INTERACTION 830.0 0.83 STRING 36370105
H31 HIRA â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 24981860 29568061 25281560 34079125
H31 UBN2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 25281560 24981860 34079125
H31 UBN1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 29568061 25281560 24981860
NASP ASF1B â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26496610 24981860
ASF1B UBN1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 24981860
ASF1B UBN2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 24981860
RPA2 ESR1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 31527615 11953755
UBN2 HIRA â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 24981860 19029251
HIST1H4F RBBP7 â—¼   PHYSICAL_INTERACTION 832.0 0.83 STRING 36370105
CHAF1A CHAF1B â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
CABIN1 HIRA â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
ASF1B IPO4 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
ELK3 SP4 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HuRI 32296183
NFU1 HIRA â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 11342215
MYC HIRA â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 21150319 23602572 29467282
POLR2A SMARCB1 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
CHAF1A RBBP4 â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
H3F3A HIST1H4F â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST1H4F HIST2H3C â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
H3F3A SMARCA4 â—¼   PHYSICAL_INTERACTION 845.0 0.84 STRING 36370105
JUN PML â—¼   PHYSICAL_INTERACTION 848.0 0.84 STRING 36370105
ESR1 RBBP7 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 23403292 31527615 18577416 21182205
H3F3A IPO4 â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
HIST2H3C IPO4 â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
HIST1H2BK HIST2H3C â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
ASF1A HIST2H3C â—¼   PHYSICAL_INTERACTION 865.0 0.86 STRING 36370105
ASF1B HIST2H3C â—¼   PHYSICAL_INTERACTION 865.0 0.86 STRING 36370105
ASF1B H3F3A â—¼   PHYSICAL_INTERACTION 865.0 0.86 STRING 36370105
H33 NASP â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 20504901 25416956 14718166
ASF1A UBN2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 24981860 26496610 28514442 34079125
HMGA1 JUN â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 10357819 10428834
MYC IPO4 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 17314511 29467282 17353931
HIST1H4F SMARCA4 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
H3F3B SMARCA4 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
ASF1A ASF1B â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
ASF1A UBN1 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
SMARCA2 SMARCA4 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
H31 RBBP7 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 25330109 29263092 20080577 19410544 29568061 26527279 16622419
ASF1A H3C2 â—¼   PHYSICAL_INTERACTION ✅ 0.88 0.88 mint 24981860
H3C2 ASF1A â—¼   PHYSICAL_INTERACTION ✅ 0.88 0.88 mint 7219095 19498464
H3C2 ASF1A â—¼   PROXIMITY ✅ 0.88 0.88 mint 25281560
ESR1 ASF1A â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 21217774 31527615
ESR1 BTF3 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 18025262 31527615
ESR1 HSPA8 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
DNAJA2 HSPA8 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
HIST1H4F RUVBL1 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
H3F3B IPO4 â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
H31 IPO4 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 22407294 19498464 29568061 28514442 14718166 26527279 19410544
H31 RBBP4 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 11850410 27098840 33961781 29263092 19410545 16622419 20080577 19498464 26527279 29568061 14718166 16728976 31435636 19410544
H33 HIRA â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 19410545 22195966 24209620 9731536 20211137 21047901 14718166
NASP H3C2 â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 24981860
H3C2 NASP â—¼   PROXIMITY ✅ 0.89 0.89 mint 25281560
UBN1 ASF1A â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 22401310 33961781 24981860 19029251 26496610 23602572 28514442 34079125
HIRA ASF1B â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 24981860 16980972 28514442 26527279
JUN ESR1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 17317669 16713569 23747343 11477071
PML JUN â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10620019 16916642 9671405 15626733
MYC PML â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 17146439 21150319 32592588 30415952 15735755
HIRA UBN1 â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
RBBP4 RBBP7 â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
MYC PHB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11983916 12695333
ASF1B H31 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 12842904 24981860 25281560 17353931 26167883 22407294 34079125 20504901 19498464 29568061 28514442 27753532 14718166 26527279 15664198 19410544
ASF1A H31 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 20393127 33961781 24981860 26167883 10759893 22407294 34079125 29568061 18971269 23828041 19498464 14718166 28514442 20504901 25281560 15664198 19410544
NASP H31 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 28514442 33961781 20167597 32296183 25281560 16189514 24981860 34079125 20080577 20504901 19498464 29568061 25416956 14718166 26527279 19410544
H31 HAT1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 25330109 24981860 34079125 20080577 20504901 19498464 26527279 29568061 14718166 25281560 19410544
ASF1B H3C2 â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 24981860
H3C2 ASF1B â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 7219095 19498464
H3C2 ASF1B â—¼   PROXIMITY ✅ 0.9 0.9 mint 25281560
ASF1B RBBP4 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 28514442 27705803 17353931
MECP2 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21655924 23242655 15870696
GTF2I MYC â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 17314511 30415952 8377829 29467282
UBN1 HIRA â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 22401310 33961781 24981860 19029251 22195966 23602572 27217568 21807893
MYC HSPA8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11983916 12695333
MYC IRF2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
IRF2 SAMHD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18281489 10075021 11058120
MAP3K7 TIFA â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 17496917 15327770 19675569
MYC RBBP4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
PML UBE2I â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
SMARCA4 TCF7L2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 19571879 11532957 21654818
H3F3B HIRA â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
H3F3B HIST2H3C â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
H3F3A HIST2H3C â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
ASF1B CHAF1A â—¼   PHYSICAL_INTERACTION 905.0 0.9 STRING 36370105
CHAF1A H3C2 â—¼   PHYSICAL_INTERACTION ✅ 0.91 0.91 mint 7219095 19498464
H3C2 CHAF1A â—¼   PHYSICAL_INTERACTION ✅ 0.91 0.91 mint 7219095 19498464
H3C2 CHAF1A â—¼   PROXIMITY ✅ 0.91 0.91 mint 25281560
ASF1A H3F3B â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
HIST1H2BK HIST1H4F â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
HIST1H4F RBBP4 â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
HAT1 HIST1H4F â—¼   PHYSICAL_INTERACTION 919.0 0.91 STRING 36370105
CHAF1B H3C2 â—¼   PHYSICAL_INTERACTION ✅ 0.92 0.92 mint 24981860
H3C2 CHAF1B â—¼   PHYSICAL_INTERACTION ✅ 0.92 0.92 mint 7219095 19498464
H3C2 CHAF1B â—¼   PROXIMITY ✅ 0.92 0.92 mint 25281560
ASF1A RBBP4 â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
RPA1 TP53BP1 â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
ASF1A CHAF1B â—¼   PHYSICAL_INTERACTION 929.0 0.92 STRING 36370105
HAT1 RBBP4 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
HAT1 NASP â—¼   PHYSICAL_INTERACTION 939.0 0.93 STRING 36370105
H33 RBBP4 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 33961781 14718166 19410545 27705803
ASF1B H33 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 33961781 26167883 24209620 23075851 20504901 20651253 14718166 15664198
CHAF1A CHAF1B â—¼   PHYSICAL_INTERACTION 948.0 0.94 STRING 36370105
ASF1A H33 â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 33961781 24209620 18971269 23075851 20504901 23828041 27217568 14718166 15664198
SMARCB1 SMARCA4 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 24981860
ASF1B HIST1H4F â—¼   PHYSICAL_INTERACTION 953.0 0.95 STRING 36370105
ASF1B HIRA â—¼   PHYSICAL_INTERACTION 954.0 0.95 STRING 36370105
POLR2A SMARCA2 â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
NASP RBBP4 â—¼   PHYSICAL_INTERACTION 957.0 0.95 STRING 36370105
ASF1B ASF1A â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 24981860 22407294 26496610 12842904 34079125
RBBP4 HAT1 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 33961781 25416956 24981860 26344197
POLR2A SMARCA4 â—¼   PHYSICAL_INTERACTION 963.0 0.96 STRING 36370105
HIST1H4F TP53BP1 â—¼   PHYSICAL_INTERACTION 967.0 0.96 STRING 36370105
ASF1A NASP â—¼   PHYSICAL_INTERACTION 969.0 0.96 STRING 36370105
ASF1B NASP â—¼   PHYSICAL_INTERACTION 969.0 0.96 STRING 36370105
HAT1 RBBP7 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
ASF1B CHAF1B â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
H3F3B HIST1H4F â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
RBBP7 HAT1 â—¼   PHYSICAL_INTERACTION 0.98 0.98 HIPPIE 33961781 28143904 26344197 24981860 22939629 26186194 20953179 27705803 28514442
SMARCA2 SMARCB1 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
ASF1A HIST1H4F â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
ASF1B H3F3B â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
ASF1A HIRA â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPA1 RPA2 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
SMARCA4 SMARCB1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
H1-0 ASF1A â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 15621527 23964094 17242207 17158953 15655109 17242198 16901784
H1-0 HMGA2 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 15621527 23964094 17242207 17158953 15655109 17242198 16901784
H1-0 HIRA â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 15621527 23964094 17242207 17158953 15655109 17242198 16901784
H1-0 UBN1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 15621527 23964094 17242207 17158953 15655109 17242198 16901784
H1-0 CABIN1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 15621527 23964094 17242207 17158953 15655109 17242198 16901784
H1-0 HMGA1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 15621527 23964094 17242207 17158953 15655109 17242198 16901784
CDK2 H1-5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15607961 15753125 14612406 17570479 7629134
MEF2D JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9252389 7760790 12054430
ASF1B H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11985607 17353931 15664198 27753532 12842904
ASF1A H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15664198 10759893 11985607
RPA2 APEX1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11687589 9214649 11601988 10744741
RPA1 APEX1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11687589 9214649 11601988 10744741
MYC APEX1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 14519204 11983916 12695333 11085504
HMGA1 ASF1A â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 15621527 23964094 17242207 17158953 15655109 17242198 16901784
HMGA2 ASF1A â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 15621527 23964094 17242207 17158953 15655109 17242198 16901784
ASF1A CHAF1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 16980972 11897662
ASF1B CHAF1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 16980972 17145710 17353931 11897662
UBN1 CABIN1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 19029251 15621527 21807893 17242207 17242198
HMGA2 CABIN1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 15621527 23964094 17242207 17158953 15655109 17242198 16901784
HMGA1 CABIN1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 15621527 23964094 17242207 17158953 15655109 17242198 16901784
HIRA CABIN1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 19029251 15621527 21807893 17242207 17242198
MYC CDK2 â—¼   PHYSICAL_INTERACTION 34.0 1.0 ACSN 11274345 11283614 12545156 14536078 15147722 15155580 15279786 17055429 17303408 17550342 17558397 17660363 17873522 18590585 18636226 19887899 20027199 20237412 20551172 20581311 20713526 20818389 21406394 21733352 2191300 21919891 22067385 23140366 23869868 24954210 25002027 28536364 7575488 9618481
MYC CDK2 â—¼   SHARES_COMPLEX 34.0 1.0 ACSN 11274345 11283614 12545156 14536078 15147722 15155580 15279786 17055429 17303408 17550342 17558397 17660363 17873522 18590585 18636226 19887899 20027199 20237412 20551172 20581311 20713526 20818389 21406394 21733352 2191300 21919891 22067385 23140366 23869868 24954210 25002027 28536364 7575488 9618481
CDK2 RPA2 â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 ACSN 14536078 15147722 15175241 15279786 15677884 16581787 17038621 17102137 17116885 17296725 17303408 17582221 17660363 17713585 18590585 18636226 19793801 7575488
CDK2 RPA1 â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 ACSN 14536078 15147722 15175241 15279786 15677884 16581787 17038621 17102137 17116885 17296725 17303408 17582221 17660363 17713585 18590585 18636226 19793801 7575488
CDK2 HMGA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 17960875 17570479 21319273
CDK2 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 10428798 22431515 23390529 17570479 23770852
CDK2 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 8386367 27653698 17081983 19966300 18669648 29896817 17570479 20713526 17558397 15103331 22348395 20445224
CDK2 HIRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 20068231 11238922 19413330
CTCF RBBP7 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17851529 17761849 25135475 17185360
CTCF RBBP4 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17851529 17761849 25135475 17185360
CTCF MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 10625678 8649389 2284094 12032779 19568426 24725430 12524457 8246978 12897849 9591631 1795697
ESR1 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11477071 17963131 10037443 16679312
ESR1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 22396492 21835891 15073177 18193094 11517191 21505052 22892083 8707895 19569049 14722073 18414489
SMARCA4 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9099865 18451880 11003650
JUN ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11477071 17317669 16713569
ESR1 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11477071 17317669 16713569
HMGA1 HIRA â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 15621527 23964094 17242207 17158953 15655109 17242198 16901784
HMGA2 HIRA â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 15621527 23964094 17242207 17158953 15655109 17242198 16901784
HMGA1 HMGA2 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 15621527 23964094 17242207 17158953 15655109 17242198 16901784
HMGA1 UBN1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 15621527 23964094 17242207 17158953 15655109 17242198 16901784
HMGA2 UBN1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 15621527 23964094 17242207 17158953 15655109 17242198 16901784
HNF1B HNF4A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10518495 8290348 11585914 16479257
HNF4A MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12591729 23714368 19966299 15024077
JUN MYC â—¼   ENZYMATIC_REACTION ✅ 40.0 1.0 ACSN 11274345 11929833 11955436 11967263 12051714 15001769 15576399 15768032 15806138 16007074 16039586 16169192 16510874 17050667 17143292 17291450 17439715 17936032 18347071 18627596 19619488 19623618 20006983 20122174 20530697 20705860 20920541 21285352 21767405 22290435 22705350 22761862 23306204 23343194 24023259 25730849 26587781 7542250 8545107 8666229
JUN MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 21835891 8276360 1774959 2498162 21607323 20410304 14523011 18037408
UBE2I JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 11877416 16713569 16055711 10788439 8733011
JUN MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 29.0 1.0 Omnipath 15806138 16510874 22290435 18627596 19623618 11929833 23343194 15768032 22761862 17050667 16039586 20122174 17291450 20920541 17143292 20006983 17439715 15576399 21767405 23306204 8545107 22705350 18347071 16007074 16169192 21285352 20530697 19619488 11274345
TCF7L2 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 12095419 19561604 19895682 15579438 26947016 16204248 12799378 12907606 17360646 9727977 21533051 20133699 15576399 19784072 24447505 12591729 20818421 18852287 11973610
TCF7L2 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 17306568 17666529 23343194 21285352 15576399 21151179 22761862 22290435 16039586 19619488 19623618 17143292
SMARCB1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 10319872 14559996 14964309 19234532
RPA2 RPA1 â—¼   PHYSICAL_INTERACTION 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA2 RPA1 â—¼   SHARES_COMPLEX 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA2 RPA1 â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
TCF7L2 RUVBL1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 9843967 14695187 16510874 15829968 11080158
SMARCB1 SMARCA4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 17145710 10078207 18414052 23540691 20506188 8895581 31759698
TP53BP1 DCD â—¼   KO_UP_REGULATES ✅ + 1.58 1.58 PKG 28854368
TP53BP1 TP53BP1 â—¼   KO_DOWN_REGULATES ✅ - -9.54 9.53 PKG 28854368