Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
TP53 E2F7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22802528
RBM7 HNRNPK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
KAT5 AR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 10364196 5211544
AR TP53 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19481544 7103716
AR RCHY1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20610535 16914734
AR NEDD4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20610535 18703514
AR HSPA5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20610535 21125667
AR RARA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12069693 20610535
AR TUBB3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12775765 21734264
AR RORA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24119295 20610535
HNRNPK AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18413735
AR MME â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11162897
UBE2I ATM â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
CHEK2 ATM â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 19001859 12364621
CHEK2 ATM â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 16651405 10724175
ATR KAT5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12791985 16327781
TP53 ATR â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 9925639 10435622
EPC1 BRD8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 17320397 19164757
BRD8 MRGBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 17320397 19164757
BRD8 ING3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 17320397 19164757
BRD8 DMAP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 17320397 19164757
BRD8 TRRAP â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 17320397 19164757
EPC1 BRD8 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 17320397 19164757
BRD8 MRGBP â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 17320397 19164757
BRD8 DMAP1 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 17320397 19164757
BRD8 ING3 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 17320397 19164757
BRD8 TRRAP â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 17320397 19164757
TCF3 CDK6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 21788410
CHEK2 KAT5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 19001859 12364621
CHEK2 KAT5 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 16651405 10724175
CHEK2 SOD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 30576923 24647101
COPS5 TYK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24043623
TP53 CREBBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 10823891 5212595
HIF1A CREBBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17382325 5219810
RORA CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24226095 14687547
CUL3 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HNRNPK DDX17 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
DDX20 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTT DDX39A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
DKC1 SHQ1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 22923768 23551398
MRGBP DMAP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 17320397 19164757
EPC1 DMAP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 17320397 19164757
DMAP1 ING3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 17320397 19164757
DMAP1 TRRAP â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 17320397 19164757
MRGBP DMAP1 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 17320397 19164757
EPC1 DMAP1 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 17320397 19164757
DMAP1 TRRAP â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 17320397 19164757
DMAP1 ING3 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 17320397 19164757
EHMT2 FZR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22178396 15774718
RUVBL2 EP400 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218484 16601686
YY1 EPAS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19483472
EPC1 ING3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 17320397 19164757
EPC1 MRGBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 17320397 19164757
EPC1 TRRAP â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 17320397 19164757
EPC1 ING3 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 17320397 19164757
EPC1 MRGBP â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 17320397 19164757
EPC1 TRRAP â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 17320397 19164757
NCL FBL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18292223 0712387105
FDFT1 RUVBL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
YY1 GNAS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18458536
HIF1A HDAC5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19071119 6802010
HDAC6 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TUBA1A HDAC6 â—¼   DEACETYLATION ✅ 2.0 0.8 intact 5215415 12024216
HINT1 TRIM29 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8216426 7644499
HNRNPK HNRNPA2B1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PHF20 HNRNPA2B1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
TP53 HNRNPK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8200620 21821029
UBE2I HNRNPK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
PABPC1 HNRNPK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
HNRNPK RBM10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
HNRNPK HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TYK2 HNRNPK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 29892012 25416956
HNRNPR PSTPIP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
TP53 HSPA5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17184779 5219502
SMARCA2 HSPA5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
HSPA5 TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPD1 INO80B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
HSPD1 MAPKAPK5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
TUBA1A HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MCRS1 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
NDN HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MORF4L2 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
VCP HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
INO80E HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PELO HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
KAT5 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
UBE2I HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PPP1CA HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTT TGFBR2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
IKZF1 UBE2I â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
PPP1CA IKZF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21750978 19282287
UBE2I IKZF3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
MRGBP ING3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 17320397 19164757
ING3 TRRAP â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 17320397 19164757
MRGBP ING3 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 17320397 19164757
ING3 TRRAP â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 17320397 19164757
TGFBR2 INO80C â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
UBE2I KAT5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
KAT5 TELO2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
KAT5 PELO â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
KPNA1 TERT â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
LEF1 TCF3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8479911
TP53 MAP1B â—¼   COLOCALIZATION 2.0 0.8 intact 18656471 6700545
MAP1LC3A PRPF40A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15383276 5217202
MAP2K6 MAPK8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11460167 10882101
MAPK7 RPS6KA2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12832467 16626623
TBP MAPK8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17074809 19620725
MAPKAPK5 MAPK8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10978313 11274345
TBP MAPK9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17074809 19620725
MEN1 TERT â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12837246
TRIM29 MLH1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
TP53 MLH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15781865
MRGBP TRRAP â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 17320397 19164757
MRGBP TRRAP â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 17320397 19164757
MTOR RPS6KA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15060135
NCBP2 NCBP1 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
TP53 NCL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22103682 8291914
NCL SMNDC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
TP53 NDN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10713459 10347180
TP53 PMS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
TP53 PPP1CA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
PRKDC UPF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18158334
UBE2I PRPF40A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
RORA PSMC5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
PSMC5 TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TP53 PTMA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9185588 18856068
RCHY1 TP53 â—¼   COLOCALIZATION 2.0 0.8 intact 5220017 17568776
UBE2I RUVBL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18087039 0710343105
RUVBL2 TERT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18358808
TUBB SOD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TBP TERT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7666533 17967894
TGFBR2 UCHL5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22344298 16027725
TGFBR2 YY1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TP53 TRRAP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12138177 11779500
VCP TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TUBB TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TRIM33 TRIM28 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1101544108 21531907
UBE2I TRIM28 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18082607
TRIM29 UBE2I â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
VCP UBXN6 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
UBXN6 VCP â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
PDRG1 RPAP3 â—¼   PHYSICAL_INTERACTION 802.0 0.8 STRING 36370105
NCBP2 PRPF40A â—¼   PHYSICAL_INTERACTION 804.0 0.8 STRING 36370105
MAPK8 MAPK9 â—¼   PHYSICAL_INTERACTION 805.0 0.8 STRING 36370105
KPNA1 SOX2 â—¼   PHYSICAL_INTERACTION 806.0 0.8 STRING 36370105
TP53 MME â—¼   KO_UP_REGULATES ✅ + 0.8 0.8 PKG 28854368
ATM CHEK2 â—¼   PHOSPHORYLATION ✅ + 0.8 0.8 Signor 10973490
PDRG1 URI1 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
PRPF19 RBM8A â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
PRPF8 RBM8A â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
ACTL6A MRGBP â—¼   PHYSICAL_INTERACTION 818.0 0.81 STRING 36370105
POLR2E PPP1CA â—¼   PHYSICAL_INTERACTION 818.0 0.81 STRING 36370105
MLH1 PMS2 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
MRGBP EAF1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 15647280 16230350
CFTR USP9X â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31324722 17110338
U2AF2 DDX17 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22365833 26641092
MBTD1 DMAP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 27153538
MBTD1 EP400 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 27153538 29028833
ING3 EP400 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26496610 29028833
EPC1 EP400 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 27153538 29028833
MBTD1 EPC2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 27153538
VPS72 EPC2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 15647280
TRRAP EPC2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 26496610
VPS72 ING3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 15647280 26496610
YY1 INO80 â—¼   PHYSICAL_INTERACTION ✅ 0.82 0.82 mint 24981860
MBTD1 TRRAP â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 27153538 31281901
SKP2 OFD1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SOX2 PAK1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RBBP5 SOX2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30089852 35140242
RBM8A SMG9 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 20371770 19417104
RBM8A SMG8 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 20371770 19417104
INO80 YY1 â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
KPNA1 NCBP2 â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
PIH1D1 UXT â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
RUVBL1 YY1 â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
INO80E MCRS1 â—¼   PHYSICAL_INTERACTION 823.0 0.82 STRING 36370105
RUVBL2 YEATS4 â—¼   PHYSICAL_INTERACTION 823.0 0.82 STRING 36370105
INO80D RUVBL2 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
INO80D UCHL5 â—¼   PHYSICAL_INTERACTION 825.0 0.82 STRING 36370105
RUVBL2 TTI1 â—¼   PHYSICAL_INTERACTION 825.0 0.82 STRING 36370105
RUVBL2 TELO2 â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
ACTL6B SMARCA2 â—¼   PHYSICAL_INTERACTION 827.0 0.82 STRING 36370105
CTBP1 E2F7 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 26186194 31041561 35016035
CCNA2 CCNA1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
VPS72 BRD8 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 15647280 31753913
KAT5 BRD8 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 14966270 27153538 20946988 26186194 31753913 28514442
MBTD1 BRD8 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 27153538 31753913
HDAC6 CFTR â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 31501480 14675537 22069321
EHMT2 CTBP1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 17967884 16702210 26186194 28514442 31041561
MRGBP EP400 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 15647280 12963728 28514442 29028833
VPS72 EPC1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 27153538 15647280 29028833
TRRAP EPC1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 27153538 26496610 29028833
KAT5 EPC2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 27153538 20946988 26186194 28514442
MCRS1 INO80 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 24981860 16230350 21303910 17721549
MRGBP MBTD1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 27153538 17573780
UCHL5 MCRS1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 24981860 17721549 26186194 28514442 18922472
PHF20 MCRS1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 24981860
MCRS1 TFPT â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 17721549 24981860 16230350
TTI1 MTOR â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 22544753 20810650 20427287
WDR5 SOX2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 30089852 29383478 35140242
SOX2 USP9X â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 31605775 23667531
CFTR HSPA4 â—¼   PHYSICAL_INTERACTION 832.0 0.83 STRING 36370105
ACTL6A INO80E â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
INO80B INO80E â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
INO80C INO80E â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
INO80D INO80E â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
INO80E TFPT â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
AR RCHY1 â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
DDX23 NHP2L1 â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
NDN TP53 â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
TUBA1A TUBB â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
DMAP1 ZNHIT1 â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
ACTR6 VPS72 â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
ATR CHEK2 â—¼   PHOSPHORYLATION ✅ + 0.83 0.83 Signor 10973490
DKC1 NHP2L1 â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
PSMC5 VCP â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
RBM7 NCBP2 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 26382858 26496610
NPHP1 NPHP3 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 12872122 16713569
PRKDC TELO2 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
TELO2 RPAP3 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 24656813 20801936
CCNA1 SKP2 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
BRD8 RUVBL2 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
CREBBP TCF3 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
PDRG1 URI1 â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
PIH1D1 PPP1CA â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
MEN1 WDR5 â—¼   PHYSICAL_INTERACTION 845.0 0.84 STRING 36370105
ACTL6A ACTR5 â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
POLR2E RUVBL1 â—¼   PHYSICAL_INTERACTION 848.0 0.84 STRING 36370105
TRRAP BRD8 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33961781 12963728 26496610 31753913
CFTR PRKDC â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 26618866 29924966 17110338
EP400 MORF4L2 â—¼   PHYSICAL_INTERACTION 850.0 0.85 STRING 36370105
HCFC1 MEN1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 23508102 24981860 15199122
IKZF1 TBP â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 16713569 11959865
YY1 INO80E â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 24981860
NPHP1 INVS â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 12872123 16189514 16713569
TTI1 PRKDC â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 20810650 20371770 20427287
TTI1 TRRAP â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 20371770 26496610 20427287
EIF6 FBL â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
MORF4L2 MRGBP â—¼   PHYSICAL_INTERACTION 0.85 0.85 HuRI 32296183
HNRNPA2B1 HNRNPK â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
PSMC5 RARA â—¼   PHYSICAL_INTERACTION 854.0 0.85 STRING 36370105
TRRAP VPS72 â—¼   PHYSICAL_INTERACTION 854.0 0.85 STRING 36370105
EP400 VPS72 â—¼   PHYSICAL_INTERACTION 855.0 0.85 STRING 36370105
NHP2L1 NUFIP1 â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
CCNA1 FZR1 â—¼   PHYSICAL_INTERACTION 858.0 0.85 STRING 36370105
TTI1 ATM â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 20810650 20427287
ATM PRKDC â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 10464290 10608806
TTI1 ATR â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 20810650 20427287
CUL3 PRKDC â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 26949739 21145461
SOX2 EHMT2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 35140242 23667531
SOX2 EP400 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 23667531 28794006
MEN1 RBBP5 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 17050672 24981860 14992727 23508102 15199122
DMAP1 EP400 â—¼   PHYSICAL_INTERACTION 861.0 0.86 STRING 36370105
MTOR TTI1 â—¼   PHYSICAL_INTERACTION 862.0 0.86 STRING 36370105
TELO2 TRRAP â—¼   PHYSICAL_INTERACTION 863.0 0.86 STRING 36370105
CHD8 WDR5 â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
RUVBL1 TTI1 â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
EPC1 RUVBL2 â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
EPC2 MORF4L2 â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
ACTR5 INO80E â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
CUL3 ARMC5 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 33130828 21145461
TELO2 ATR â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 20427287 17384638 20801936 18160036 19097996
CHD8 RBBP5 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 24705355 20085832
CHEK2 TP53 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
VPS72 DMAP1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 26344197 15647280 22939629 20946988 29028833
KAT5 EPC1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 32296183 14966270 27153538 20946988 26186194 28514442 29028833
MRGBP EPC1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 16230350 15647280 12963728 27153538 17573780 28514442
ING3 EPC2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 16387653 26496610
MRGBP EPC2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 16230350 15647280 17573780 28514442
FZR1 SKP2 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
HIF1A TP53 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
IKZF1 MCRS1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 28514442 25416956 32296183 33961781
UCHL5 INO80 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 24981860 28598414 21303910 26186194 28514442 18922472
INO80 INO80E â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
MRGBP KAT5 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 16230350 15647280 18218781 12963728 27153538 26186194 17573780 28514442
WDR5 MCRS1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 24981860 15960975 27705803
TELO2 MTOR â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 18160036 20801936
RPAP3 PDRG1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 17643375 25036637 33961781 24981860 19450687 31738558
UXT PDRG1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 24981860 31738558
WDR5 PHF20 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 24981860 15960975 27705803
PIH1D1 URI1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
POLR2E URI1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
TELO2 PRKDC â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 18160036 20427287 20801936
RPAP3 URI1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
RUVBL1 URI1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
TELO2 TTI2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 20810650 20801936
UCHL5 TFPT â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 24981860 19615732 17721549 26186194 28514442 18922472
KAT5 TP53 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
ATR TP53 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
CREBBP HTT â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
HIF1A HSPA4 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
PRPF8 RNF113A â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
RPAP3 UXT â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
RUVBL2 URI1 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
HSPA4 PARK2 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
INO80E RUVBL1 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
INO80E UCHL5 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
URI1 UXT â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
BAP1 HCFC1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
COPS5 TP53 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
HSPA4 TP53 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
INO80E RUVBL2 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
MCRS1 PHF20 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
MTOR TELO2 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
MBTD1 YEATS4 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
INO80E YY1 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
POLR1A POLR3A â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
TRAF6 ZRANB1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
DKC1 RUVBL1 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
KAT5 MBTD1 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
UCHL5 YY1 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
KAT5 VPS72 â—¼   PHYSICAL_INTERACTION 879.0 0.87 STRING 36370105
CDK4 CDK6 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 23455922 28205554 28628118
ILK PRKDC â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 25852190 23455922 32707033
VPS72 KAT5 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 15647280 27153538 20946988 26186194 28514442 29028833
MCM9 MLH1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 26300262 26870752
SMG1 RBM8A â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 20371770 19417104 16452507
TBP TP53 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
PRKDC TP53 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
EPC2 TRRAP â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
MAPK8 TP53 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
PPP1CA RPAP3 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
NUDT21 ZRANB1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
BRD8 MORF4L2 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
HDAC6 TUBA1A â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
PPP1CA URI1 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
ACTR6 DMAP1 â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
YEATS4 ZNHIT1 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
MRGBP RUVBL2 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
RCHY1 TP53 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
SPRTN VCP â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
BRD8 KAT5 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
HTT VCP â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
MRGBP BRD8 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 20051959 33961781 24981860 16230350 15647280 12963728 31753913 17573780 28514442
ING3 BRD8 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 16387653 26496610 31753913
ING3 DMAP1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 14966270 26496610 16387653 20946988
ING3 EPC1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 16387653 27153538 26496610 14966270
ING3 YEATS4 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
TP53 RCHY1 â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 17568776 5220017
TP53 RCHY1 â—¼   COLOCALIZATION ✅ 0.89 0.89 mint 17568776 5220017
TTI2 TTI1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 20810650 20801936
ATM CHEK2 â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
CFTR VCP â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
RUVBL2 YY1 â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
BRD8 YEATS4 â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
DKC1 RUVBL2 â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
ING3 RUVBL1 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
MRGBP RUVBL1 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
MRGBP YEATS4 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
ATR TELO2 â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
DDX23 LSM4 â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
ING3 MRGBP â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
INO80B ZRANB1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
PPP1CA CAD â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 4092695
RARA CCNA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11090075
TP53 CCNA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17530187 15456866
YY1 ACTR5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22951020
LEF1 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16741972 16474850 19351848
AR TBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20610535 9238003
AR MME â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20610535 11162897 16949732
AR CDK6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20610535 15790678
PAK1 ARAF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15710605
TP53 ATM â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 9843217 9733515 9733514
KAT5 ATM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16141325
ATM METTL3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 32615088 17525332
CUL3 CAND1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 21145461 21249194 22013077 16449638 22405651 26286618 12609982
CAND1 SKP2 â—¼   DOWN_REGULATES ✅ - 3.0 0.9 ACSN 12504025 12504026 15537541
SKP2 CCNA2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 20160477 33989513 9858587 33422522 24632684 15355997 7553852 26496610 16209941 27720894 31181401 26186194 10559858 28514442 18604603
HIF1A CCNA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21029732 16399861 19304911
SKP2 CCNA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 9858587 15355997 33989513
CCNA2 SKP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9858587 15355997 33989513
WDR5 CHD8 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 18378692 20085832 24705355 15960975
COPS5 HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11707426 18926707
YY1 CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 9238849 21852380
RARA CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23321499 16417649 21110951
UBE2I CTBP1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 20176810 20098713 12679040
IKZF1 CTBP1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 27107012 21900206 24722188 16713569 10766745 25416956 16189514
CTBP1 RBBP5 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
UBE2I DDX17 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 22713328 19995069 25114211
RUVBL1 DKC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18358808
EP400 KAT5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 20351180 14966270
YY1 HCFC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8661027 23000143
HIF1A TUBB3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18178340 21176881
HIF1A RORA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15270719 14742449
TP53 HNRNPR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16980608
TP53 HSPA5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15212714 20097177 18840615
IKZF1 IKZF3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17383641
TP53 ITFG1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16980608
TERT LEF1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 19571879 11532957 21654818
TP53 MLH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18431400 15781865
TP53 NME1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12669312 16440314
TP53 PMS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15781865
PRKDC VCP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16140914
RUVBL1 TERT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18358808
SMARCAD1 TRIM28 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21549307 18675275
VCP SPRTN â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 22902628 23042605 23042607
STK17A TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17339337
TTI1 TELO2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 20810650 20427287 20801936 22863883 20371770
CCNA2 SKP2 â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
KAT5 RUVBL2 â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
VPS72 YEATS4 â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
LSM4 NHP2L1 â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
NHP2L1 PRPF8 â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
PSMC5 UCHL5 â—¼   PHYSICAL_INTERACTION 907.0 0.9 STRING 36370105
KAT5 MRGBP â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
MRGBP VPS72 â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
EPC1 MORF4L2 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
KAT5 MORF4L2 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
TUBB TUBB3 â—¼   CORRELATES + 0.91 0.91 CCLE 31978347
ECD PRPF8 â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
ATM TP53 â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
PABPC1 SMG1 â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
DPCD RUVBL2 â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
NCBP2 SMG1 â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
CAND1 CUL3 â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
ING3 KAT5 â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
ATM TELO2 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
COPS5 CUL3 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
DMAP1 KAT5 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
MBTD1 YY1 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
RUVBL2 VPS72 â—¼   PHYSICAL_INTERACTION 919.0 0.91 STRING 36370105
ACTL6A KAT5 â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
DKC1 FBL â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
INO80C RUVBL2 â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
TP53 UBE2I â—¼   PHYSICAL_INTERACTION 921.0 0.92 STRING 36370105
POLR2E TBP â—¼   PHYSICAL_INTERACTION 924.0 0.92 STRING 36370105
ACTL6A INO80 â—¼   PHYSICAL_INTERACTION 928.0 0.92 STRING 36370105
RUVBL1 UCHL5 â—¼   PHYSICAL_INTERACTION 928.0 0.92 STRING 36370105
RUVBL1 YEATS4 â—¼   PHYSICAL_INTERACTION 929.0 0.92 STRING 36370105
INO80C RUVBL1 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
VPS72 ZNHIT1 â—¼   PHYSICAL_INTERACTION 936.0 0.93 STRING 36370105
ACTL6A RUVBL2 â—¼   PHYSICAL_INTERACTION 936.0 0.93 STRING 36370105
KAT5 RUVBL1 â—¼   PHYSICAL_INTERACTION 936.0 0.93 STRING 36370105
EPC2 KAT5 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
KAT5 YEATS4 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
ACTL6A EP400 â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
EPC1 KAT5 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
LSM4 PRPF8 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
INO80 INO80C â—¼   PHYSICAL_INTERACTION 942.0 0.94 STRING 36370105
TRRAP YEATS4 â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
PIH1D1 RUVBL1 â—¼   PHYSICAL_INTERACTION 946.0 0.94 STRING 36370105
PIH1D1 RUVBL2 â—¼   PHYSICAL_INTERACTION 946.0 0.94 STRING 36370105
ACTL6A RUVBL1 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
EP400 TRRAP â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
EPC2 MRGBP â—¼   PHYSICAL_INTERACTION 948.0 0.94 STRING 36370105
SMG1 SMG8 â—¼   PHYSICAL_INTERACTION 948.0 0.94 STRING 36370105
EP400 KAT5 â—¼   PHYSICAL_INTERACTION 950.0 0.95 STRING 36370105
RUVBL2 ZNHIT1 â—¼   PHYSICAL_INTERACTION 951.0 0.95 STRING 36370105
EP400 YEATS4 â—¼   PHYSICAL_INTERACTION 951.0 0.95 STRING 36370105
EP400 MRGBP â—¼   PHYSICAL_INTERACTION 951.0 0.95 STRING 36370105
DPCD RUVBL1 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
PRPF19 U2AF2 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
RUVBL2 TRRAP â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
DMAP1 EPC1 â—¼   PHYSICAL_INTERACTION 953.0 0.95 STRING 36370105
INO80B RUVBL2 â—¼   PHYSICAL_INTERACTION 953.0 0.95 STRING 36370105
KAT5 TRRAP â—¼   PHYSICAL_INTERACTION 953.0 0.95 STRING 36370105
ACTL6A DMAP1 â—¼   PHYSICAL_INTERACTION 954.0 0.95 STRING 36370105
INO80B RUVBL1 â—¼   PHYSICAL_INTERACTION 954.0 0.95 STRING 36370105
PRPF19 RNF113A â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
UBXN6 VCP â—¼   PHYSICAL_INTERACTION 957.0 0.95 STRING 36370105
EPC1 YEATS4 â—¼   PHYSICAL_INTERACTION 959.0 0.95 STRING 36370105
DMAP1 RUVBL2 â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
EPC2 YEATS4 â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
TUBA1A TUBB3 â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
ACTR5 INO80C â—¼   PHYSICAL_INTERACTION 963.0 0.96 STRING 36370105
ATM ATR â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
EP400 RUVBL2 â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
EP400 RUVBL1 â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
INO80 INO80B â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
ACTL6A SMARCA2 â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
RUVBL2 UCHL5 â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
DMAP1 VPS72 â—¼   PHYSICAL_INTERACTION 967.0 0.96 STRING 36370105
ACTL6A TRRAP â—¼   PHYSICAL_INTERACTION 969.0 0.96 STRING 36370105
HCFC1 WDR5 â—¼   PHYSICAL_INTERACTION 969.0 0.96 STRING 36370105
NCBP2 NCBP1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 11545740 24981860 9933612 22939629 26496610 26382858 26264872 31448526 26344197 17190602 32814053 12374755 29997244 29101316 31467278 22365833 29395067 19668212 16189514 7478990 23665581 12434151
SMG1 SMG9 â—¼   PHYSICAL_INTERACTION 970.0 0.97 STRING 36370105
RUVBL1 ZNHIT1 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
NUFIP1 ZNHIT3 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
DMAP1 MRGBP â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
RUVBL1 VPS72 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
SMG1 UPF1 â—¼   PHOSPHORYLATION ✅ + 0.97 0.97 Signor 23356578
ACTR5 INO80B â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
DMAP1 RUVBL1 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
SMARCAD1 TRIM28 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
RPAP3 RUVBL1 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
ATR CHEK2 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
RPAP3 RUVBL2 â—¼   PHYSICAL_INTERACTION 979.0 0.97 STRING 36370105
TELO2 TTI1 â—¼   PHYSICAL_INTERACTION 979.0 0.97 STRING 36370105
CREBBP TP53 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
NPHP1 NPHP4 â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
ACTR6 ZNHIT1 â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
SMG8 SMG9 â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
PIH1D1 RPAP3 â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
ACTR6 RUVBL1 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
FBL NHP2L1 â—¼   PHYSICAL_INTERACTION 989.0 0.98 STRING 36370105
DMAP1 YEATS4 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
PMS2 MLH1 â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 20706999 33961781 25502805 30770470 10748159 22939629 26496610 16338176 18768816 17148452 11793469 14676842 11429708 10037723 15225546 12799449 12584560 17581638 25077178 20533529 16083711 11292842 20978114 22252508 18206974 12810663 19015241
RUVBL1 TRRAP â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
POLR1A POLR2E â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
POLR2E POLR3A â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
ACTR6 RUVBL2 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
NCBP2 RBM8A â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
PABPC1 RBM8A â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
RBM8A SMG1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
RBM8A UPF1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
SMG1 UPF1 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
ACTR5 RUVBL1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CREBBP HIF1A â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
ACTR5 RUVBL2 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
INO80 RUVBL2 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
NCBP1 NCBP2 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
ACTR5 INO80 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
DDX23 PRPF8 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
INO80 RUVBL1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PRPF19 PRPF8 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RBBP5 WDR5 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RUVBL1 RUVBL2 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
TERC DKC1 â—¼   PHYSICAL_INTERACTION 15.0 1.0 ACSN 10197982 10995457 11283614 17055429 17327415 18566586 19387550 19662498 20027199 20473778 20713526 2191300 21945180 22869732 23551398
TERC DKC1 â—¼   SHARES_COMPLEX 15.0 1.0 ACSN 10197982 10995457 11283614 17055429 17327415 18566586 19387550 19662498 20027199 20473778 20713526 2191300 21945180 22869732 23551398
ACTL6A ATM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16141325
TP53 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 17202838 18084622 18945670 11504717
AR SMARCA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20610535 17721441
AR CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 9822653 15350180 16492776 16344550 11161315 18819102 18031230 20610535
KAT5 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 11591700 10364196 19150978 11994312 16713569
CREBBP AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 20541699 9822653 15691881 12810069 9482849 16713569
RCHY1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 12200228 16713569 27903893 17721809 16914734
UBE2I AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 10383460 8798622 19692572 12764129
MAPK8 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 24424504 21512132 21820033 16282370
AR UBE2I â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 10383460 8798622 19692572 12764129
MLH1 ATM â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 9781043 16322221 16123081 11292842 10928988
ATM CHEK2 â—¼   ENZYMATIC_REACTION ✅ 59.0 1.0 ACSN 11331603 11850621 11877377 12086603 12556884 12607003 14614141 14988723 15136767 15140942 15175241 15242590 15279786 15375219 15377654 15459660 15485915 15798197 15964794 16163361 16332722 16531125 16713580 16805667 16818604 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17660363 18006705 18087292 18469862 18543256 18583988 18584027 18590585 18678890 18809224 18995830 19151707 19282663 19342888 19622404 19686080 19772495 19793801 20051983 20723763 21376743 22743550 23847781 24050180 7575488 9407949 9488723
PMS2 ATM â—¼   UP_REGULATES ✅ + 16.0 1.0 ACSN 12556884 15136767 15703371 16332722 16612326 16697054 16713580 16858402 17303408 17581638 18157157 18406444 18543256 19151707 19847258 20478261
MLH1 ATM â—¼   UP_REGULATES ✅ + 16.0 1.0 ACSN 12556884 15136767 15703371 16332722 16612326 16697054 16713580 16858402 17303408 17581638 18157157 18406444 18543256 19151707 19847258 20478261
ATR ATM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 15510216 10608806 17478428 17124492
TELO2 ATM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18160036
ATM UPF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17525332 15175154 18158334
ATM TRIM28 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 73.0 1.0 Omnipath 25128619 22496453 34194047 30323812 26158765 16862143 28607002 19584288 20858735 28851455 18285803 34419074 17833484 22491012 25404613 21642969 28439615 27364555 27602502 26671524 23096706 23935532 28739276 24754998 25905708 28847822 24461736 23318425 23346550 17178852 27432546 27820601 17942393 21868291 32060145 22205726 25846574 26293668 25533843 23034801 23352131 28249048 23633913 17525332 18657500 24794298 23645696 26212333 23050241 22715096 27376578 23370278 24657165 29540829 25173936 19071136 28847828 20424263 34518220 25956864 23554604
ATM HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 27245613 24681585 21095578 18971907 21095582 27027353 23573973 27068951 25956861 23707302 26942179
ATM TRAF6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20932475 21872579
ATM PRKDC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 47.0 1.0 Omnipath 17189255 12231622 17303408 24492479 10464290 22230547 15677476 16822724 28985363 29088817 16163361 32868446 19549901 25818648 22923485 19103741 17570479 27939942 19808981 23847781 22355272 24714417 15964794 21376743 31983282 25224041 16908529 12607003 19244120 17525332 15459660 34249431 28107384 12186630 25714019 11877377 26553138 27568553 19535303 15507430 26578593
ATM TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 452.0 1.0 Omnipath 25301947 21720806 23549171 10713094 16501611 15077171 24886358 17570479 19375142 22028490 16916644 14712210 19303885 9407038 11927276 26700820 28356518 15226429 10723129 19788889 12064478 19705844 26673821 22179422 20931131 19062161 27030982 22891162 17157788 19056039 15758953 12049739 15361830 26620371 25865756 22615843 10196661 10656682 11313957 25088203 15140942 12519769 16319535 24469230 12776195 17234789 27511909 29238697 24608431 12927814 16783362 11875057 16436515 22778557 15181149 12702572 10500142 15178764 28842590 28145533 11591448 17855337 22726545 20206688 26824362 21317290 26104798 24704793 9765199 11314044 16906133 17174997 21593792 17967874 10771484 15585169 19625493 15178448 17596534 16288207 15048074 18353733 24057508 19535302 29344296 23708100 29872395 23705030 25043304 33761896 18431490 21404020 15024084 22559321 12151394 24078877 12080066 33982778 16893723 10958792 18289945 27183917 26337656 29170437 18765533 10744722 21748595 18056442 24820418 15489892 16390936 24086335 28140789 23091651 34523970 32001619 23418564 15279808 21317932 21188172 27559048 16818505 17616578 11551930 19010925 11709713 24711418 28654064 18339864 11173129 17486112 10570149 29774100 18381438 21994612 29558908 15258567 9372954 25860929 16858402 33692124 15775976 34107253 19923893 24958101 10436023 14752509 19962312 19071090 26438152 26093282 20123963 22444248 9843217 17525332 15456784 23533526 11780126 20353948 29290977 11096068 28102346 18855897 20372057 24395704 23890999 15725625 15806145 34103468 18345031 16997395 16293623 28477117 19828454 27630139 12071847 22002314 21315088 27177180 12645530 12890678 26113041 15794754 18560558 22099307 9885574 28903382 15665826 24877058 18332866 10611322 24380814 14871840 19934315 22975381 16489034 18406507 21440540 33687951 10608806 23892398 20730097 16914171 15782130 15177184 22055193 18490454 25867001 24349352 18045533 20663147 17535811 20506250 23982736 22375140 15700044 15279774 19266268 24358288 18697815 14729946 20637859 12242661 12771937 17371838 31940492 19409520 10528155 24037342 17257427 11121242 15310764 23148227 28915641 26928575 21423215 11865061 16949371 27810895 18449195 20711232 27389279 22213803 16713569 10446957 22797063 16478990 29048667 15489221 17241873 21187893 21441950 23907539 20005840 9733514 26244501 21614094 12082529 10467728 10714958 32061892 16636671 29147215 10673501 12091386 25202122 21465263 19544417 25823026 24078903 24038750 22198295 21480565 15177039 28182994 28208785 18674635 20183804 18818083 9925639 17712528 15254178 11483158 27940348 26675349 26261212 19717643 12606585 24559687 14871926 23150668 21329876 28153791 12518062 12767922 23824039 11711532 19251701 28118604 15078887 12393500 17456577 20976220 23380594 12519780 20810927 15533933 22420423 17108107 20145032 18032786 18785202 22037398 23184057 31968249 16729035 12588868 21614932 11546806 18614045 14757188 15029243 14968111 22649771 25512053 34496248 18604166 17609585 17976513 16223874 25433195 18985806 9363941 15159397 34282274 29301278 24505404 26056062 23577291 18272544 18715874 19536869 29334356 10801407 15155458 25201202 24376853 19907922 23525106 14643431 28340339 28051100 19085961 15212693 22201816 20026654 16322229 20080565 9733515 15632067 18672098 22577550 25691451 12637545 12548019 11672523 26984736 12324477 16552184 22084686 10864201 14744854 21532626 17118344 19482562 9561848 12511424 17668048 23358251 18511169 21460853 22022355 12939400 21415014 17292432 25651062 23168260 12111733 16648554 30361254 23678107
ATM CHEK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 176.0 1.0 Omnipath 26683224 17303408 28852018 10713094 20080130 27545311 9488723 15342622 23941746 26485758 28937603 15279786 24882580 10744722 15125777 25746763 18583988 28051860 17570479 16531125 21329876 23892398 19607708 16940182 26643553 20396397 28259974 25361978 17660363 15459660 19375317 25247188 16311512 23118481 20498628 22030216 25613496 22420423 9407949 17918214 12493754 20859824 26158765 15700044 27558808 11901158 27602502 20637859 16163361 20599567 23638118 16481012 12242661 23847781 12024051 15140942 11728459 12454775 16936775 25450480 28950914 26295265 20160490 22319212 24349411 18006705 20723763 18678890 12805407 20860841 23386996 24050180 11668173 27271602 29304495 12447382 24798733 9889122 23347679 18794134 21147465 21421565 26516160 17715138 21376743 19440053 12773400 10973490 17174984 26442630 15694385 11877377 29022904 18809224 11850621 18787700 12718885 19481982 22743550 20372057 15212693 16085488 19101576 29555944 25954303 24473398 18087292 16794575 24492479 24244353 19793801 25404613 21102523 29156743 23253087 16997395 7575488 25808488 20647331 18584027 21851590 21315088 23705030 15629715 29741650 21772273 11025670 18590585 26610585 15964794 29434792 20068082 23006513 19881958 19230643 12607003 24769180 25249630 15024084 19772495 25714019 18603484 25173936 23666059 19473886 27568553 22808196
MLH1 ATR â—¼   ENZYMATIC_REACTION ✅ 16.0 1.0 ACSN 12556884 15136767 15703371 16332722 16612326 16697054 16713580 16858402 17303408 17581638 18157157 18406444 18543256 19151707 19847258 20478261
PMS2 ATR â—¼   ENZYMATIC_REACTION ✅ 16.0 1.0 ACSN 12556884 15136767 15703371 16332722 16612326 16697054 16713580 16858402 17303408 17581638 18157157 18406444 18543256 19151707 19847258 20478261
ATR CHEK2 â—¼   ENZYMATIC_REACTION ✅ 42.0 1.0 ACSN 11438669 11877377 14988723 15136767 15459660 15485915 15798197 15867354 16332722 16540648 16713580 16731533 16885023 17102137 17116885 17296725 17303408 17384638 17582221 18048416 18511906 18543256 18677104 18716619 18756267 18931676 18995830 19004803 19282663 19357644 19490890 19622404 19686080 19772495 19788416 19793801 19793861 19841479 20019063 20051983 9488723 9858600
ATR UPF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18158334 17478428
ATR CHEK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 38.0 1.0 Omnipath 21722802 20859824 26683224 18677104 19622404 15798197 19793801 27545311 23137030 19836377 20647331 20599567 19282663 19658174 17116885 16481012 17582221 11715017 17384638 29741650 12024051 18802408 10973490 9857181 26442630 15459660 17296725 11877377 17102137 12493754
ATR TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 106.0 1.0 Omnipath 17145710 22778941 24395704 28468838 12401524 15159397 24877058 15254178 9733515 11483158 15806145 19056039 11875057 15865930 11551930 11883897 19923893 12548019 18697815 29170437 16293623 19010925 11709713 10446957 9363941 21748595 17272272 22797063 12242661 10196661 22084686 10747897 10608806 10673501 12091386 17118344 23892398 9765199 15489221 24037342 15140942 10435622 17241873 10597277 10801407 11711532 17174997 21593792 25201202 9843217 10606744 15024084 15226429 15922368 21415014 21480565 15585169 24947324 9925639 23380594 9733514 11865061 19625493 16390936 10951572 10570149 23311997 12111733 26144601
ATR PRKDC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 12186630 22592045 22057367 24500207 18077418 16908529 15507430 29309644
TP53 CCNA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 16931621 8270002 9275177 19671680 16571800 8641461 9360984 21952947
CCNA2 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 14640983 10884347 16713569
CHEK2 TP53 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 10710310 10673501 10570149 10673500
TP53 CHEK2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 15326376 19435816 10531348 19395378 15044452
PRKDC CHEK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 77.0 1.0 Omnipath 31959038 12607004 22669845 18948271 16794575 24492479 15829965 23684611 12805407 20406977 26929199 21482692 27818175 20660628 33870196 11668173 21731742 33879618 15618221 11901158 24421316 21099343 12386164 15096610 24415760 12447382 12855706 15213307 16150728 20599567 16024600 17570479 12447371 28750002 34244606 33901880 15367709 26505995 16940182 33747205 11025670 12024051 24844881 15668230 10973490 20713355 33961649 19151762 16936775 16798742 12607003 30001349 18644861 25361978 20305300 11390408 20501833 15361851 16982735 23380594 15674326 17237275 20160490 20498628 33851958 15282313 25550082 31609975 15975956 11085506 12493754
CHEK2 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 111.0 1.0 Omnipath 18778462 25545885 16893723 15254178 18833288 23892398 12052256 18319725 25372714 15459660 20514219 25174607 28140789 17339337 22420423 18566216 20950777 20651945 15810020 15700044 22891162 17157788 11551930 18725978 10724175 15467443 23351141 20096447 11063934 11709713 15659650 12242661 10656682 15140942 20041275 11728459 18614044 12781359 22649771 18812180 11173129 10570149 15279785 20081365 20860841 11875057 22778557 19923893 24553354 22797063 26384650 23316480 15489221 19788416 10801407 21187893 9843217 9733514 10710310 24358900 21526939 23843721 29805302 9733515 25404613 12548019 21625617 10673501 11447225 17118344 26610585 19544417 28038466 12810724 25823026 15024084 17464182 15862297 19933256 20526329 12111733 20183804 23144912
CREBBP LEF1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 10769018 11050151 18160704 15060161 11973335 10775268
HIF1A CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12542982 20547241 17452336 15907483 19489936 15342390 15184875
TP53 CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 19057620 15632413 11466559 19448667 19880525 9891054 22198284 10833421 11709699 10435630 11390631 9890939 21191649 12501250 11928223 17434128 12164786 24330748 11779500 10435595 21513889 10777477
HTT CREBBP â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 11264541 11607033 16456924 15994095 17500595 16713569 10823891
CREBBP TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 49.0 1.0 Omnipath 17303408 25545885 27618436 19220000 16713569 10823891 15632413 19805293 25451029 15279786 10473588 12154097 7575488 16537920 10848610 18485870 19880525 10648616 20144767 14722092 14759370 18590585 26976603 9194564 19788416 25314079 19166313 12426395 9288775 11782467 17660363 19234109 21390126 10196247 17434128 19357310 10551785 22084066
PAK1 CTBP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 28007610 12872159 16999872 18354494 20361981 23291169
MAPK8 CTBP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 23.0 1.0 Omnipath 28532298 14567915 17496919 19591900 21372320 19788416 15708980 8608010 16984892 20512932 20220133 21438496 20054826 19616017 23762064 15611655
VCP CUL3 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 33444648 11733065 28115426 15652483 10811609 29153394
HIF1A EPAS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20513003 18174278 16924414 19030186
HIF1A TERT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18754863 15048086 17699105 16961934
HIF1A HSPA4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15794924 14726529 20068160 18844219 18683594
HIF1A TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 12542982 17390008 9537326 15780936 11696352 10469629 17236590 20706634 15629713 11007955
TP53 HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 9537326 16713569 12124396 15629713 16882692
MAPK8 HNRNPK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11259409 11231586
HNRNPK TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 18472002 16360036 23092970
PRKDC HNRNPU â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 27303920 25986610 19351595 25030905 19844162
TBP HSPA4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8648740 9199313 16330756 8218418
YY1 HSPA5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 16452489 15899857 15760841 8972185
TP53 HTT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22399227 15996546 16978870 16278683
TP53 HTT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18431400 32814053 16713569 10823891
ILK TGFBR2 â—¼   DOWN_REGULATES ✅ - 6.0 1.0 ACSN 11696562 15905178 24527345 25100717 25268583 27111285
PAK1 ILK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 22521536 25738875 27642646 17420447
KAT5 LEF1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 9843967 14695187 16510874 15829968 11080158
KAT5 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17188038 15310756 18280244 16601686
KAT5 PRKDC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16603769 16904321
LEF1 TRRAP â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 9843967 14695187 16510874 15829968 11080158
PAK1 MAP2K3 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 10661401 11062502 11385609 11907067 12885870 14764585 15536084
MAP2K3 MAPKAPK5 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 17254968 9628874 8622669 12808055
PAK1 MAP2K3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 7592586 11304531 15677464 11309380 14970210
TGFBR2 MAP2K6 â—¼   ENZYMATIC_REACTION ✅ 17.0 1.0 ACSN 11274345 12738796 14557817 15265520 15282297 16200688 16474430 17934056 18855897 20060931 20519943 21614932 22703233 23070005 24132110 24336330 24403530
TRAF6 MAP2K6 â—¼   ENZYMATIC_REACTION ✅ 19.0 1.0 ACSN 11274345 12620219 12738796 14660645 15125833 16252010 16878026 17704786 17948050 18264787 18758450 18855897 18922473 18977329 19161412 21614932 23070005 23681101 23811849
MAP2K6 MAPKAPK5 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 17254968 9628874 8622669 12808055
PAK1 MAP2K6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 7592586 11304531 15677464 11309380 14970210
TRAF6 MAP2K6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 21614932 12738796 11274345 16313339 18855897
TP53 MAPK8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 22607268 23376463 18374905 15958553 10854211 22353755
PRKDC MAPK8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11749722 16319174
TRAF6 MAPK8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10346818 17965022 15692051 17947236
MAPK8 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 37.0 1.0 Omnipath 11108663 12531896 16713569 11283254 10706102 19651615 27147566 9724739 15538975 9732264 10581258 10436023 17570479 9393873 11896587 12514174 15580310 18813780 11078726
MAPK8 RARA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10383391 15657432 21272161
MAPK9 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 79.0 1.0 Omnipath 12356735 14665630 26158765 18778462 12969974 12861053 15254178 17135248 18669630 12384533 17363488 17698850 11283254 10706102 21454683 18931691 11551930 11397945 14612532 15064747 15963507 11175334 11423984 27147566 29234486 24657168 10581258 14517211 17353187 10673500 22030623 14527925 22728651 17525747 15629715 9393873 11447225 15671037 22285752 17245430 15140942 28673515 23871434 11078726 20041275 11896587 16731759 17121812 33514736 11861384 25431954 12810724 17967874 12955074 21832239 16818520 12756247 23798621 11526498 20009884 16713569 10202145 11850826 11896572 10710310 10570149 12959929 15269203 11583595 21148320
MAPKAPK5 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 17145710 17624785 23685072 26295581 24818748 18568040 17254968
NCBP2 METTL3 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 9409616 24316715 24407421 24981863
NCBP1 METTL3 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 9409616 24316715 24407421 24981863
MLH1 PMS2 â—¼   PHYSICAL_INTERACTION 40.0 1.0 ACSN 10882712 11900249 12556884 12648680 12947387 15136767 15703371 16332722 16612326 16697054 16713580 16858402 17036055 17303408 17581638 17884153 18157157 18406444 18543256 18931676 19151707 19473888 19595721 19596235 19596236 19622404 19686080 19805513 19809470 19847258 20173781 20478261 21376743 22101340 22257761 22373527 22743550 22824526 23085398 24050180
MLH1 PMS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 45.0 1.0 Omnipath 25077178 17145710 10748159 17148452 11429708 18206974 19015241 16338176 20706999 15225546 25502805 19022408 12584560 26496610 14676842 16083711 11793469 10037723 11292842 22252508 17581638 12799449 18768816 20533529 31515488 20978114 12810663
MTOR YY1 â—¼   PHYSICAL_INTERACTION 22.0 1.0 ACSN 12150925 12408816 12533512 12906785 15755954 16469695 17680028 18046414 18048642 18492954 19022819 19568798 19864431 21157483 21981924 23087689 24795729 24973821 25002027 25730849 26159692 28216025
MTOR YY1 â—¼   SHARES_COMPLEX 22.0 1.0 ACSN 12150925 12408816 12533512 12906785 15755954 16469695 17680028 18046414 18048642 18492954 19022819 19568798 19864431 21157483 21981924 23087689 24795729 24973821 25002027 25730849 26159692 28216025
TTI1 MTOR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 20427287 20810650
TELO2 MTOR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 20427287 18160036
NDN TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 24722188 10347180 16713569 23785149
PPP1CA TRIM28 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20424263
PPP1CA TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 16501611 16713569 15231748 15178317
PRKDC TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 79.0 1.0 Omnipath 15355354 19398950 15254178 9372954 11483158 7862459 16713569 11875057 11551930 11883897 12548019 25168287 8502477 11709713 10446957 28145533 22726545 24886358 16552184 12242661 17570479 10196661 10747897 9885574 10673501 12091386 22355272 9765199 15489221 9561848 10801407 22504299 22444248 15177184 11042698 10358069 10470151 10606744 9744860 16397295 12959929 12064478 27130668 10951572 12111733 25937999 15381073 28102346 9363941 19918261
PRKDC TRIM28 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19444312 27432546 23370278
WDR5 RBBP5 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
WDR5 RBBP5 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
RCHY1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 23.0 1.0 Omnipath 21988832 19483087 17568776 24367557 25116336 21084285 12654245 21791603 20452352 19043414 16713569 31630802 27519799 19918835
UPF1 SMG1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 11544179 11331269 19359157 19417104 16452507 14636577 20817927
SMG1 UPF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 29768215 24115769 11544179 11331269 25535763 25013172 23356578 19417104 21965535 18423202 15175154 23826386
SMG1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 18332866 15279777 15175154 18679436
UPF1 SMG9 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 11544179 11331269 19359157 19417104 16452507 14636577 20817927
TP53 TERT â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 15656906 12807729 15067344 15734740 11064449 15262117 16234237 10778946 15371422 22496369 18754863 19649288 19787269
TGFBR2 TRAF6 â—¼   ENZYMATIC_REACTION ✅ 32.0 1.0 ACSN 11013220 11133108 12154066 12717440 12724770 12767520 12809600 14557817 15265520 15548370 16474430 17673906 17934056 18758450 18922473 19010789 19050695 19109155 19920116 20060931 20519943 20644162 21278795 21614932 21900405 22703233 22710166 22943793 24132110 24336330 7594497 9865696
TGFBR2 TRAF6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 50.0 1.0 Omnipath 12717440 19050695 11133108 14557817 19920116 22710166 19114990 12767520 22703233 23331499 11013220 20060931 17934056 21614932 17673906 20644162 24132110 18922473 9865696 22943793 20519943 21900405 12154066 7594497 18758450 15548370 24336330 21278795 12724770 19010789 15265520 16474430 26192618 12809600 19109155
YY1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10787423 10634504 8816507 10505791 18391986
UBE2I TRIM28 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 17942393 17079232 25114211 18488044 17298944 18082607
PRKDC ATM â—¼   KO_DOWN_REGULATES ✅ - -1.5 1.49 PKG 28854368
ATM ATM â—¼   KO_DOWN_REGULATES ✅ - -2.25 2.25 PKG 28854368
PRKDC PRKDC â—¼   KO_DOWN_REGULATES ✅ - -4.22 4.21 PKG 28854368