Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
NHEJ1 XRCC4 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
NOP56 SNU13 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
SNU13 NOP58 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
GEMIN4 DDX20 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 10725331 5212337
YWHAZ NUFIP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
RUVBL1 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
RUVBL2 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
XRCC4 GNG7 â—¼   KO_DOWN_REGULATES ✅ - -0.83 0.82 PKG 28854368
BRCA1 CDK9 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 22990118 28278048
NOP58 RUVBL1 â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
CRMP1 DPYSL2 â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
NHP2L1 NUFIP1 â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
XRCC4 NUFIP1 â—¼   KO_UP_REGULATES ✅ + 0.86 0.86 PKG 28854368
DDX20 GEMIN4 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
PRPF31 RUVBL1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
GEMIN4 SMN1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
GEMIN6 SMN1 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
SMN1 DDX20 â—¼   PHYSICAL_INTERACTION ✅ 0.88 0.88 mint 11714716 5214807
DPYSL2 DPYSL3 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
DPYSL2 DPYSL5 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
CRMP1 DPYSL3 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
DPYSL3 DPYSL5 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
NOP58 RUVBL2 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
XRCC4 NHEJ1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 21070942 31548606 21768349 17567543 26774286 18064046 21349273 29997244 16439205
DPYSL2 CRMP1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
NOP56 NOP58 â—¼   CORRELATES + 0.92 0.92 CCLE 31978347
NHEJ1 NUFIP1 â—¼   KO_UP_REGULATES ✅ + 0.94 0.94 PKG 28854368
SMN1 GEMIN2 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 11714716 5214807
DDX20 GEMIN2 â—¼   PHYSICAL_INTERACTION 964.0 0.96 STRING 36370105
DDX20 SMN1 â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
CDK9 CCNT1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 14627702 23455922 19914168 30652970 24981860 14580347 21697490 20535204 11713532 22939629 26659056 22959624 11145967 16980611 15713661 23602568 12115727 11689688 17643375 10574912 9499409 12832472 20305087 30649429 26344197 10617616 27684187 18483487 9872325 19818711 16109377 12894230 15328539 12944466 15546612 32707033 15713662 20153263 19387490 18566585 22483617 21729782 20562857 24367103 28514442 15528190 10465067 11713533 10958691 9491887 17700062 23064645 26186194 11282025 12588988 15107825
NUFIP1 ZNHIT3 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
NHEJ1 XRCC4 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
NHP2L1 NOP56 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
NHP2L1 NOP58 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
NOP56 NOP58 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
GEMIN2 SMN1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
RUVBL1 RUVBL2 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCNT1 CDK9 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
NHP2L1 PRPF31 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
NHEJ1 XRCC4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 22228831 21349273 18064046 21070942 17567543 29997244 16439205 21768349
NHEJ1 GNG7 â—¼   KO_DOWN_REGULATES ✅ - -1.05 1.04 PKG 28854368
XRCC4 ZNHIT6 â—¼   KO_UP_REGULATES ✅ + 1.33 1.33 PKG 28854368
NHEJ1 PPP3R1 â—¼   KO_DOWN_REGULATES ✅ - -1.69 1.68 PKG 28854368
NHEJ1 CALB2 â—¼   KO_DOWN_REGULATES ✅ - -1.86 1.85 PKG 28854368
XRCC4 XRCC4 â—¼   KO_DOWN_REGULATES ✅ - -6.32 6.31 PKG 28854368
NHEJ1 NHEJ1 â—¼   KO_DOWN_REGULATES ✅ - -6.47 6.46 PKG 28854368