APAF1
|
CASP3
|
â—¼ CLEAVAGE
|
✅
|
|
2.0
|
0.8
|
intact
|
5214497
11550094
|
CASP9
|
CASP3
|
â—¼ CLEAVAGE
|
✅
|
|
2.0
|
0.8
|
intact
|
0707715105
18723680
|
CASP3
|
CASP9
|
â—¼ CLEAVAGE
|
✅
|
|
2.0
|
0.8
|
Reactome
|
12011067
15573119
|
PTMA
|
CASP3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9334214
10675528
|
CDK2
|
KAT5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
25558984
22231403
|
EP300
|
CREBBP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
23403292
24998469
|
ESR1
|
EP300
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16704985
11279135
|
EP300
|
MEF2A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12371907
11796223
|
MYC
|
HDAC2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20697349
|
MYC
|
RAN
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23468463
11085504
|
ESR1
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
3677090
|
RAN
|
NUPR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16478804
0508955103
|
TP53
|
CREBBP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
10823891
5212595
|
TP53
|
JUN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
11350971
10984493
|
TP53
|
DVL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
TP53
|
PHB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
7717349
20134482
|
MAX
|
TP53
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
7969121
10348347
|
TP53
|
TRRAP
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12138177
11779500
|
TP53
|
ZDHHC5
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
28775165
|
TP53
|
PTMA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9185588
18856068
|
TP53
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10766163
16713569
|
TP53
|
PCNA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
7915517
|
HDAC1
|
PCNA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
18691180
9650586
|
JUN
|
ACTB
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10840940
11082319
|
BCAR1
|
ACTB
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
6174726
18164686
|
RCC1
|
RAN
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
7878053
1944575
|
TAL1
|
HDAC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
0900437106
19497860
|
HDAC1
|
RBPJ
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
9694793
|
TAL1
|
HDAC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
0900437106
19497860
|
KLF16
|
SIN3A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11438660
12036432
|
MEF2A
|
IL2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17559812
14722108
|
ESR1
|
CREBBP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
23403292
24998469
|
ESR1
|
BMI1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
24559156
16582100
|
PHB2
|
PHB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
MEF2A
|
PHB2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
21689744
15173318
|
PHB2
|
MEF2A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
15173318
|
TERF2IP
|
TERF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
0605303103
16880378
|
EP300
|
HDAC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.81
|
0.81
|
HIPPIE
|
14968110
30110629
22778253
16787918
33742100
18722353
22731250
|
PHB2
|
VDAC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
809.0
|
0.81
|
STRING
|
36370105
|
SMARCB1
|
ACTL6A
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.82
|
0.82
|
mint
|
24981860
|
MYC
|
CDK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
17314511
29467282
|
CDK2
|
CDK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
21319273
|
ACTB
|
EP300
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33742100
21988832
|
EP300
|
KLF8
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
35140242
20107328
|
KAT5
|
BMI1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
27295567
16169070
|
MYC
|
PHB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
35140242
29467282
|
MYC
|
JUN
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
21150319
20232342
|
JUN
|
HDAC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
17056544
25609649
|
CBP
|
KLF8
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
35140242
20107328
|
PTMA
|
PDIA4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
22863883
24981860
|
PTMA
|
PTMS
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
22939629
24981860
|
PTMA
|
VDAC2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
31536960
30719818
|
CDK1
|
CDK17
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
NUPR1
|
RAN
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
19650074
16478804
32780723
|
C1QBP
|
PHB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
34079125
32877691
22904065
|
MAX
|
SIN3A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
29028833
33961781
25609649
|
EP300
|
PCNA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
831.0
|
0.83
|
STRING
|
36370105
|
ESR1
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
835.0
|
0.83
|
STRING
|
36370105
|
KAT5
|
MYC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
837.0
|
0.83
|
STRING
|
36370105
|
EP300
|
RAN
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
12649209
33742100
|
MYC
|
ACTB
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
11839798
29467282
|
RAN
|
SMARCB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
839.0
|
0.84
|
STRING
|
36370105
|
PCNA
|
CCNB1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
28514442
7903056
33961781
8101826
|
ESR1
|
SET
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
31527615
20348541
|
MAX
|
TRRAP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
845.0
|
0.84
|
STRING
|
36370105
|
CASP9
|
CASP3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
11242052
8900201
25241761
1067155
15941357
11230124
15507451
18723680
17437405
|
HDAC2
|
PTMA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
12634383
16713569
|
NCOR1
|
PTMA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
12634383
16713569
|
CDK2
|
TP53
|
â—¼ PHOSPHORYLATION
|
✅
|
+
|
0.86
|
0.86
|
Signor
|
24173284
|
OTUB1
|
PCNA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
26752685
18954305
|
HDAC1
|
PTMA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
12634383
16189514
16713569
|
SET
|
PTMA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
16189514
15556635
|
ACTB
|
ACTL6A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
868.0
|
0.86
|
STRING
|
36370105
|
CDK2
|
CBP
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
33961781
26186194
23602568
23455922
|
MYC
|
EP300
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
15616592
16287840
32140074
16126174
17157259
12776737
|
MYC
|
HDAC2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
17314511
20195357
22286234
30415952
|
HDAC1
|
RUVBL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
869.0
|
0.87
|
STRING
|
36370105
|
ESR1
|
ACTB
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
31527615
20308691
19805454
21182203
21182205
20348541
|
PHB2
|
HDAC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
24051437
15173318
15140878
|
PHB2
|
PTMA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
12943695
16189514
|
ESR1
|
PHB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
10938099
24051437
12943695
26052702
17932104
19805454
28555617
10359819
15140878
|
CASP3
|
CASP9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
KAT5
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
871.0
|
0.87
|
STRING
|
36370105
|
HDAC2
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
873.0
|
0.87
|
STRING
|
36370105
|
ESR1
|
PHB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
873.0
|
0.87
|
STRING
|
36370105
|
ESR1
|
HDAC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
877.0
|
0.87
|
STRING
|
36370105
|
CREBBP
|
ESR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
878.0
|
0.87
|
STRING
|
36370105
|
EP300
|
CBP
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
9267036
25314079
10899165
31753913
30110629
15598887
17970752
|
EP300
|
MEF2A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
12371907
20590529
|
PTMA
|
KEAP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
23318954
25416956
32296183
25582950
|
TAL1
|
HDAC2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
16407974
19497860
|
SIN3A
|
TAL1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
10688671
11118214
|
KPNB1
|
RCC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
879.0
|
0.88
|
STRING
|
36370105
|
CBP
|
PTMA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
16713569
11897665
|
CREBBP
|
JUN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
887.0
|
0.88
|
STRING
|
36370105
|
MYC
|
TRRAP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
888.0
|
0.88
|
STRING
|
36370105
|
EP300
|
PTMA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
11967287
10891508
16713569
|
KAT5
|
MYC
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
12776177
15572685
18003922
35140242
30415952
20946988
|
MYC
|
CBP
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
35140242
16878156
12776737
29467282
|
MYC
|
CDK4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
22094256
28205554
28628118
21988832
|
NUPR1
|
PTMA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
19650074
16478804
|
TRRAP
|
ESR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
31527615
11931763
16260778
12738788
12837248
|
CDK4
|
PCNA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
33961781
8259215
11254741
8101826
|
JUN
|
ESR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
17317669
11477071
16713569
23747343
|
MYC
|
CASP9
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12695333
|
CCNB1
|
CDK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
34224728
18337751
9891079
24508230
17431037
9560267
14681455
17283331
8662825
19162005
16159883
25852190
20360007
19879842
12397081
11331587
9247342
26496610
20228808
25750436
12612082
16784539
23602568
20733055
27626412
20367638
8397206
10973963
9001210
20956543
33037310
8397207
23543736
32707033
2570636
30674583
10716937
27030811
18408765
24358021
20974803
7799941
33961781
26186194
17679094
23799914
8463339
26344197
|
CDK2
|
EP300
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
33961781
26186194
10330164
23455922
|
PCNA
|
CDK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10930425
|
EP300
|
TAL1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
11756538
11118214
10490830
|
EP300
|
PCNA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
11268218
16713569
18263614
12937166
24939902
14988403
33742100
|
EP300
|
JUN
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
27956703
21268080
21937452
24069158
11689449
14630807
11980644
10327051
12437352
12471036
24636898
|
EP300
|
ESR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
19887647
11782371
12738788
25728767
11867769
12479814
23065768
15308690
20388208
14761960
22227247
8799122
20348541
23403292
12714702
11581164
16713569
19838210
18765668
16645043
30418174
12574227
|
EP300
|
KPNA2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10801418
15342649
|
ESR1
|
KAT5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
31527615
17418098
16260778
22081016
11591700
|
TRRAP
|
MYC
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
11839798
19818711
9708738
17314511
17353931
10611234
16705173
11511539
32140074
21150319
35140242
12660246
29467282
30415952
12077335
20946988
|
MYC
|
HDAC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
17314511
18271930
34147029
26496610
30415952
18003922
22286234
24951594
|
RBPJ
|
MYC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
18490439
10644343
16847353
|
MYC
|
PHB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
11983916
12695333
|
MYC
|
SLC25A3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12747840
|
RCC1
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
TP53
|
RBPJ
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
ACSN
|
19836055
24254977
26302407
|
TP53
|
RBPJ
|
â—¼ PROTEIN_INTERACTION
|
|
|
3.0
|
0.9
|
ACSN
|
19836055
24254977
26302407
|
TP53
|
PHB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16918502
14500729
21829624
|
TP53
|
SLC25A5
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
24076372
9671769
12080472
|
TRRAP
|
MAX
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
9708738
10611234
33961781
12660246
29028833
20946988
|
HDAC1
|
PCNA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
11929879
16189514
16713569
14988403
|
SIN3A
|
HDAC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
15695521
28514442
9520398
10640275
14647463
12398767
9150133
10444591
14593184
21258344
12943729
12374985
17956988
11102443
9885572
17962807
26496610
12453419
11171972
16331260
20585571
10220385
25314079
12091390
11931768
17643391
11602581
17827154
12724404
11784859
23752268
18059533
9790534
9804427
26949739
24981860
33961781
19182791
11118440
15451426
12920132
26344197
|
ESR1
|
HDAC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
17312152
31527615
24051437
33731348
14722073
21182205
15557281
18451880
14506733
15140878
|
KLF16
|
SIN3A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
12036432
11438660
22203677
35140242
|
NCOR1
|
ESR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
16713569
24051437
12145334
16469706
17400812
12738788
21182203
|
CBP
|
JUN
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
16713569
2138276
17296604
9786917
18443043
10327051
8028671
9659924
15994313
16055710
|
CBP
|
ESR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
11782371
16417649
18765668
17400812
14766010
27420286
23403292
9192902
8616895
11113179
|
EP300
|
HDAC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
900.0
|
0.9
|
STRING
|
36370105
|
KAT5
|
RUVBL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
901.0
|
0.9
|
STRING
|
36370105
|
EP300
|
MEF2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
903.0
|
0.9
|
STRING
|
36370105
|
EP300
|
JUN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
911.0
|
0.91
|
STRING
|
36370105
|
EP300
|
TP53
|
â—¼ POLYUBIQUITINATION
|
✅
|
-
|
0.91
|
0.91
|
Signor
|
12690203
|
KPNB1
|
KPNA2
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.92
|
0.92
|
mint
|
17596301
|
ACTL6A
|
KAT5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
920.0
|
0.92
|
STRING
|
36370105
|
CDK1
|
HIST1H1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
921.0
|
0.92
|
STRING
|
36370105
|
ACTB
|
RUVBL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
926.0
|
0.92
|
STRING
|
36370105
|
HDAC1
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
927.0
|
0.92
|
STRING
|
36370105
|
EP300
|
ESR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
930.0
|
0.93
|
STRING
|
36370105
|
ACTL6A
|
RUVBL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
936.0
|
0.93
|
STRING
|
36370105
|
KAT5
|
RUVBL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
936.0
|
0.93
|
STRING
|
36370105
|
ACTB
|
RUVBL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
937.0
|
0.93
|
STRING
|
36370105
|
KAT5
|
ACTB
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.94
|
0.94
|
HIPPIE
|
27153538
10966108
20946988
|
HDAC2
|
HDAC1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.94
|
0.94
|
mint
|
26949739
|
ACTL6A
|
RUVBL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
947.0
|
0.94
|
STRING
|
36370105
|
NCOR1
|
SIN3A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.95
|
0.95
|
HIPPIE
|
17210713
11430826
16713569
|
RUVBL2
|
TRRAP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
952.0
|
0.95
|
STRING
|
36370105
|
KAT5
|
TRRAP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
953.0
|
0.95
|
STRING
|
36370105
|
CASP9
|
APAF1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.96
|
0.96
|
mint
|
5221774
9390557
|
CCNB1
|
CDK2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
20733051
28514442
9891079
7799941
8397207
25852190
26496610
33961781
26186194
23602568
10995390
23455922
30674583
18471975
|
PCNA
|
CDK2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
12361598
28514442
26496610
29510343
9545286
33961781
26186194
7903056
21319273
10930425
|
KAT5
|
TRRAP
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
28514442
27153538
16387653
20070254
33961781
10966108
26186194
14966270
20946988
|
HDAC1
|
TAL1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
10688671
16407974
19497860
|
ACTL6A
|
SMARCB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
968.0
|
0.96
|
STRING
|
36370105
|
ACTL6A
|
TRRAP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
969.0
|
0.97
|
STRING
|
36370105
|
RAN
|
RCC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
28514442
16189514
7882974
12194828
31467278
10827954
1961752
18617507
11336674
20565941
7988569
10811801
22939629
10369786
29997244
7891706
33961781
26186194
26344197
|
HDAC2
|
HDAC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
28514442
25241761
9520398
11287668
19703393
30737378
17894944
10444591
11466315
11777905
21258344
15297431
17956988
11102443
9885572
12032298
19041848
26496610
22416134
12493763
11739383
10581039
11804585
11564889
21670149
22939629
9150135
11919195
23752268
18059533
16713569
9804427
20388487
9790534
26949739
24981860
33961781
15987735
19182791
15451426
12920132
26344197
|
SIN3A
|
HDAC2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
16254079
12398767
21258344
12943729
9885572
9150134
12453419
12493763
14749338
22493095
12082111
25314079
12091390
17827154
12724404
23752268
18059533
9804427
26949739
24981860
15451426
26344197
|
TERF2IP
|
TERF2
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.97
|
0.97
|
mint
|
8286516
21829167
|
TP53
|
EP300
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.98
|
0.98
|
mint
|
16611888
6599495
|
CDK4
|
PCNA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
980.0
|
0.98
|
STRING
|
36370105
|
TERF2
|
TERF2IP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
981.0
|
0.98
|
STRING
|
36370105
|
CCNB1
|
CDK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
982.0
|
0.98
|
STRING
|
36370105
|
CREBBP
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
983.0
|
0.98
|
STRING
|
36370105
|
APAF1
|
CASP9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
987.0
|
0.98
|
STRING
|
36370105
|
RUVBL1
|
TRRAP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
990.0
|
0.99
|
STRING
|
36370105
|
KPNA2
|
KPNB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
991.0
|
0.99
|
STRING
|
36370105
|
CDK2
|
PCNA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
RAN
|
RCC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
KPNB1
|
RAN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
PSMA1
|
PSMA3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
RUVBL1
|
RUVBL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
CDK2
|
HIST1H1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
EP300
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
MAX
|
MYC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
ANP32A
|
APAF1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
ACSN
|
11864614
12522243
14622304
15087373
17377525
18439902
|
PTMA
|
APAF1
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
6.0
|
1.0
|
ACSN
|
11864614
12522243
14622304
15087373
17377525
18439902
|
TP53
|
APAF1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
12883670
11559530
15077176
18951482
11896574
17043642
15972851
11591730
11389439
|
ANP32A
|
APAF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
15087373
14622304
12522243
17377525
11864614
18439902
|
TP53
|
APAF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
11591730
11559530
11423996
11389439
|
CASP3
|
APAF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
12874265
21827945
11550094
|
APAF1
|
CASP9
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
63.0
|
1.0
|
Omnipath
|
17145710
15829969
15024710
9390557
19494828
11113115
10617566
9539746
10364241
10722681
27476169
21060833
19118655
20829884
16977332
10329646
15210107
10393175
16352606
11242052
14555243
10376594
12773388
10206961
19337385
10428850
9488720
19788417
15262985
9922454
21827945
10749135
9651578
19698783
12792650
9837928
11227497
|
TP53
|
CASP3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
22154326
22178888
23677569
15578696
17363498
24098340
18064040
23527225
10893263
21859835
|
CASP9
|
CASP3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
37.0
|
1.0
|
Omnipath
|
10708865
9390557
10508159
11230124
18723680
15657060
16977332
15507451
1067155
9708736
25241761
8900201
11242052
9765224
17437405
19788417
9812896
12620238
15941357
12181739
19465923
12792650
15725726
|
CASP3
|
BCAR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
11511102
11447317
10712510
|
CDK1
|
CASP9
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
17.0
|
1.0
|
Omnipath
|
19081073
19016842
16287866
29844931
19586613
29416675
17466630
12792650
|
CCNB1
|
CDK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
1.0
|
STRING
|
36370105
|
CDK1
|
TERF1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
9.0
|
1.0
|
ACSN
|
14551205
15279786
17303408
17660363
18414028
18590585
18625707
22624377
7575488
|
MYC
|
CDK1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
18802399
2237430
8065306
11085504
|
TP53
|
CDK1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
16.0
|
1.0
|
Omnipath
|
10825186
11593387
12874009
19472317
10514438
11313928
16807237
8270002
17942917
9275177
20395210
11032828
19861536
12889596
19067706
|
CDK1
|
KAT5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
20.0
|
1.0
|
Omnipath
|
21658600
12468530
16103124
17570479
26829474
18669648
|
CDK1
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
20.0
|
1.0
|
Omnipath
|
24173284
12767922
1584757
20661218
26029996
2141171
9467949
17570479
20808790
7862459
11327730
11078726
27726420
8357826
16713569
2156209
|
CDK1
|
RCC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
34356619
18568422
15014043
17855385
17570479
15203004
|
CDK1
|
CCNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
38.0
|
1.0
|
Omnipath
|
17145710
23799914
34224728
20117088
16784539
24358021
24508230
19470789
10973963
17283331
20228808
18347064
11242082
12397081
10362260
24582498
15582998
20367638
1833185
12447691
9001210
2570636
24101512
23543736
11331587
12524548
22726437
27626412
|
MYC
|
CDK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
34.0
|
1.0
|
ACSN
|
11274345
11283614
12545156
14536078
15147722
15155580
15279786
17055429
17303408
17550342
17558397
17660363
17873522
18590585
18636226
19887899
20027199
20237412
20551172
20581311
20713526
20818389
21406394
21733352
2191300
21919891
22067385
23140366
23869868
24954210
25002027
28536364
7575488
9618481
|
MYC
|
CDK2
|
â—¼ SHARES_COMPLEX
|
|
|
34.0
|
1.0
|
ACSN
|
11274345
11283614
12545156
14536078
15147722
15155580
15279786
17055429
17303408
17550342
17558397
17660363
17873522
18590585
18636226
19887899
20027199
20237412
20551172
20581311
20713526
20818389
21406394
21733352
2191300
21919891
22067385
23140366
23869868
24954210
25002027
28536364
7575488
9618481
|
CDK2
|
BMI1
|
â—¼ UP_REGULATES
|
✅
|
+
|
32.0
|
1.0
|
ACSN
|
11274345
11283614
12545156
14536078
15147722
15155580
15279786
17055429
17303408
17550342
17558397
17660363
17873522
18590585
18636226
20027199
20237412
20551172
20581311
20713526
20818389
21406394
21733352
2191300
21919891
22067385
23140366
23869868
25002027
28536364
7575488
9618481
|
CDK2
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
8386367
27653698
17081983
19966300
18669648
29896817
17570479
20713526
17558397
15103331
22348395
20445224
|
CDK2
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
10428798
22431515
23390529
17570479
23770852
|
CDK2
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
39.0
|
1.0
|
Omnipath
|
24173284
9315650
19413330
19664995
16083285
1088347
16552184
10884347
17570479
10747897
25241761
7624134
11687964
17287340
92065884
12064478
19556892
14640983
10348343
14702041
|
PCNA
|
EP300
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
18263614
11268218
16713569
|
EP300
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
137.0
|
1.0
|
Omnipath
|
11907332
25545885
21187340
10706102
16438982
10490106
19339993
15542844
23010591
11433299
19608861
17438265
17906639
16024799
9194564
20234175
23402884
12162806
26229107
16959611
15186775
9744860
11070080
17977830
17189186
22266186
20228809
15664194
19805293
25753752
11804596
26625199
27818144
10648616
16928824
9288740
10942770
12724314
23148227
23728348
15965232
19218448
16678111
16782091
20094059
14612423
24821727
10518217
16713569
9891054
25288747
17452980
14759370
19788416
25156994
18931695
22074660
23880760
15337767
15509808
26302407
22731250
18391200
16543236
19234109
21471221
23307557
25867071
12690203
15558054
18612383
23870121
18243116
19217391
22013068
16537920
16611888
18485870
9194565
12660246
9809062
23796514
11359905
12501250
15295102
19407812
25651062
23329847
16135789
|
EP300
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
19.0
|
1.0
|
Omnipath
|
17145710
22290435
19623618
11804596
23343194
22761862
16039586
12776737
17157259
17143292
12660246
15576399
21151179
15522869
17306568
19407812
17666529
21285352
19619488
|
KAT5
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
17188038
15310756
18280244
16601686
|
KAT5
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
12776177
19150978
15572685
34650217
|
PTMA
|
KEAP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
15657435
25416956
25582950
32296183
23318954
|
MYC
|
MAX
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
ACSN
|
11274345
12040186
15121849
16908182
2006410
8425218
|
MYC
|
MAX
|
â—¼ PROTEIN_INTERACTION
|
|
|
1.0
|
1.0
|
HIPPIE
|
16596619
21988832
10229200
17471507
26267534
15572685
18003922
20382893
35140242
17418410
25609649
16352593
31767764
17072308
17289033
10918583
9528857
14749374
21807113
19623651
18620061
25522242
32296183
16140957
16705173
19578763
26496610
12584560
17157259
17643117
24951594
20946988
10465786
12706874
12821782
9184233
17353931
10611234
32140074
8266081
20691906
16410719
21150319
10593926
12660246
27859590
12553908
8224841
10319872
2006410
16287840
16606833
23816886
9708738
17314511
9886493
27705803
33298911
33961781
20936779
12824180
9680483
17700062
29467282
30415952
12391307
|
JUN
|
MYC
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
40.0
|
1.0
|
ACSN
|
11274345
11929833
11955436
11967263
12051714
15001769
15576399
15768032
15806138
16007074
16039586
16169192
16510874
17050667
17143292
17291450
17439715
17936032
18347071
18627596
19619488
19623618
20006983
20122174
20530697
20705860
20920541
21285352
21767405
22290435
22705350
22761862
23306204
23343194
24023259
25730849
26587781
7542250
8545107
8666229
|
KLF8
|
MYC
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
23.0
|
1.0
|
ACSN
|
11955436
11967263
12051714
15001769
15576399
16039586
17143292
17306568
17666529
17671186
17936032
19619488
19623618
20705860
21151179
21285352
22290435
22761862
23343194
24023259
25730849
7542250
8666229
|
MYC
|
MAX
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
ACSN
|
11274345
12040186
15121849
16908182
2006410
8425218
|
MYC
|
BMI1
|
â—¼ UP_REGULATES
|
✅
|
+
|
32.0
|
1.0
|
ACSN
|
11274345
11283614
12545156
14536078
15147722
15155580
15279786
17055429
17303408
17550342
17558397
17660363
17873522
18590585
18636226
20027199
20237412
20551172
20581311
20713526
20818389
21406394
21733352
2191300
21919891
22067385
23140366
23869868
25002027
28536364
7575488
9618481
|
JUN
|
MYC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
21835891
8276360
1774959
2498162
21607323
20410304
14523011
18037408
|
ESR1
|
MYC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
22396492
21835891
15073177
18193094
11517191
21505052
22892083
8707895
19569049
14722073
18414489
|
MYC
|
TP53
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
10962037
10656696
8494784
10348347
19882681
16557594
19086036
15780936
14519204
16112647
11781835
7969121
11789587
9839551
|
MYC
|
PCNA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
7597041
18358094
22911891
18809243
1280813111085504
11085504
|
MYC
|
CCNB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
12747840
11522645
11983916
19470724
|
MYC
|
TRRAP
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
17848523
23775087
11511535
20194507
|
MYC
|
PTMA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
8196628
15840017
8378090
1378271
8524267
12695333
9185588
10380878
9365169
17372028
|
MYC
|
CDK4
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
15208653
12835716
24951594
21384303
14519204
22395148
10688915
17728244
11983916
18414489
|
MYC
|
MAX
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
10508165
15665468
8385351
8649388
8521822
22384171
1406956
17341548
|
MYC
|
RCC1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
9178906
14519204
9792927
12695333
|
MYC
|
IL2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
8962093
10702306
12695333
1349016
9417120
|
CREBBP
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
7575488
18590585
17303408
15522869
12776737
20144767
17660363
16878156
15279786
|
JUN
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
29.0
|
1.0
|
Omnipath
|
15806138
16510874
22290435
18627596
19623618
11929833
23343194
15768032
22761862
17050667
16039586
20122174
17291450
20920541
17143292
20006983
17439715
15576399
21767405
23306204
8545107
22705350
18347071
16007074
16169192
21285352
20530697
19619488
11274345
|
HDAC1
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
21734722
17666529
15576399
22761862
22290435
19923891
20682799
|
TRRAP
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
17145710
17353931
11511539
12660246
20194507
9708738
|
MAX
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
90.0
|
1.0
|
Omnipath
|
17145710
16287840
25609649
12821782
16606833
16596619
21807113
25522242
20691906
19578763
24951594
8224841
17643117
9528857
12391307
16705173
21150319
10229200
21988832
15572685
9680483
2006410
17314511
14749374
12553908
17289033
17418410
19623651
12824180
17157259
12584560
26496610
20946988
20936779
8425218
23816886
17353931
10319872
17471507
18003922
16140957
20382893
12660246
8266081
7565735
32296183
10465786
26267534
17072308
27705803
9184233
18620061
10918583
17700062
10593926
10611234
16352593
9708738
|
SMARCB1
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
10319872
14559996
14964309
19234532
|
GSK3A
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
12.0
|
1.0
|
Omnipath
|
11018017
17081983
2663470
11877389
14563837
8247524
16023596
15150404
|
MYC
|
CDK4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
21988832
11602341
17093053
22094256
|
ESR1
|
TP53
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
20080630
16115928
22787161
12750288
20696891
17681750
17699779
|
JUN
|
TP53
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
22859294
17321721
20697347
10348347
12963547
10072388
22353755
18604200
|
TP53
|
CREBBP
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
22.0
|
1.0
|
Omnipath
|
19057620
15632413
11466559
19448667
19880525
9891054
22198284
10833421
11709699
10435630
11390631
9890939
21191649
12501250
11928223
17434128
12164786
24330748
11779500
10435595
21513889
10777477
|
TP53
|
PCNA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
26.0
|
1.0
|
Omnipath
|
10321841
7915517
15358233
12217864
10516009
1705714
8570655
16980608
9707425
15950182
19789303
11313928
1356162
12384701
9858527
12947108
23390122
8524244
9651310
1352831
7909518
11032828
10910968
12485898
10618724
|
TP53
|
CCNB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
15.0
|
1.0
|
Omnipath
|
12874009
14627709
10051609
11313928
17942917
11892838
15710382
20395210
19470724
12379461
11071927
11522645
15737644
11162602
|
HDAC1
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
30.0
|
1.0
|
Omnipath
|
17145710
10521394
11099047
22266186
20633551
18765668
20075864
17827154
11313951
14976551
25241761
19303885
12426395
19011633
16697957
16959611
16107876
10777477
|
CREBBP
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
49.0
|
1.0
|
Omnipath
|
17303408
25545885
27618436
19220000
16713569
10823891
15632413
19805293
25451029
15279786
10473588
12154097
7575488
16537920
10848610
18485870
19880525
10648616
20144767
14722092
14759370
18590585
26976603
9194564
19788416
25314079
19166313
12426395
9288775
11782467
17660363
19234109
21390126
10196247
17434128
19357310
10551785
22084066
|
TP53
|
PHB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
24380853
16918502
20134482
14500729
16319068
16713569
|
JUN
|
PCNA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
22550165
19940138
1352831
15205327
23078099
|
RCC1
|
RAN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
21.0
|
1.0
|
Omnipath
|
26186194
10827954
11336674
18617507
10811801
29997244
31467278
16189514
7988569
10369786
20565941
1961752
|
RAN
|
KPNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
17145710
10779340
8909533
11024021
9214382
20658144
8576188
26496610
9102465
9135132
10944119
10037787
9045717
|
HDAC1
|
HDAC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
28.0
|
1.0
|
ACSN
|
11283614
12545156
12668723
14673164
15151915
15155580
15465827
16232121
17018611
17055429
17508028
17550342
17563753
20027199
20713526
20818389
21234400
21577210
21685935
21733352
2191300
21919891
22370643
22514743
22796940
23140366
23869868
9618481
|
HDAC1
|
SIN3A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
27.0
|
1.0
|
ACSN
|
11283614
12545156
12668723
14673164
15151915
15155580
15465827
16232121
17018611
17055429
17508028
17550342
17563753
20027199
20713526
20818389
21234400
21577210
21733352
2191300
21919891
22370643
22514743
22796940
23140366
23869868
9618481
|
HDAC1
|
NCOR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
ACSN
|
15465827
16127449
21234400
22796940
|
HDAC1
|
HDAC2
|
â—¼ SHARES_COMPLEX
|
|
|
28.0
|
1.0
|
ACSN
|
11283614
12545156
12668723
14673164
15151915
15155580
15465827
16232121
17018611
17055429
17508028
17550342
17563753
20027199
20713526
20818389
21234400
21577210
21685935
21733352
2191300
21919891
22370643
22514743
22796940
23140366
23869868
9618481
|
HDAC1
|
SIN3A
|
â—¼ SHARES_COMPLEX
|
|
|
27.0
|
1.0
|
ACSN
|
11283614
12545156
12668723
14673164
15151915
15155580
15465827
16232121
17018611
17055429
17508028
17550342
17563753
20027199
20713526
20818389
21234400
21577210
21733352
2191300
21919891
22370643
22514743
22796940
23140366
23869868
9618481
|
HDAC1
|
NCOR1
|
â—¼ SHARES_COMPLEX
|
|
|
4.0
|
1.0
|
ACSN
|
15465827
16127449
21234400
22796940
|
HDAC1
|
SIN3A
|
â—¼ UP_REGULATES
|
✅
|
+
|
27.0
|
1.0
|
ACSN
|
11283614
12545156
12668723
14673164
15151915
15155580
15465827
16232121
17018611
17055429
17508028
17550342
17563753
20027199
20713526
20818389
21234400
21577210
21733352
2191300
21919891
22370643
22514743
22796940
23140366
23869868
9618481
|
HDAC1
|
BMI1
|
â—¼ UP_REGULATES
|
✅
|
+
|
22.0
|
1.0
|
ACSN
|
11283614
12545156
12668723
15151915
15155580
15465827
16232121
17055429
17508028
17550342
20027199
20713526
20818389
21234400
21733352
2191300
21919891
22370643
22796940
23140366
23869868
9618481
|
HDAC1
|
HDAC2
|
â—¼ UP_REGULATES
|
✅
|
+
|
28.0
|
1.0
|
ACSN
|
11283614
12545156
12668723
14673164
15151915
15155580
15465827
16232121
17018611
17055429
17508028
17550342
17563753
20027199
20713526
20818389
21234400
21577210
21685935
21733352
2191300
21919891
22370643
22514743
22796940
23140366
23869868
9618481
|
HDAC1
|
ESR1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
21655924
23242655
18316616
20101232
|
HDAC2
|
SIN3A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
ACSN
|
14673164
15465827
17018611
17563753
21234400
21577210
22514743
22796940
|
HDAC2
|
SIN3A
|
â—¼ SHARES_COMPLEX
|
|
|
8.0
|
1.0
|
ACSN
|
14673164
15465827
17018611
17563753
21234400
21577210
22514743
22796940
|
NCOR1
|
CREBBP
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
20462215
17400812
12392082
10612426
|
NCOR1
|
RBPJ
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
18391971
9694793
|
NCOR1
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
16469706
12738788
12145334
17400812
16713569
21182203
|
TERF2
|
TERF2IP
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
32.0
|
1.0
|
Omnipath
|
17145710
19651898
15316005
27214791
10888888
21217703
19287395
15383534
26496610
23086976
19164295
15100233
16880378
26450775
21829167
10850490
28082411
23307557
21044950
14565979
|
MEF2A
|
JUN
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
12574153
10330170
20590529
9252389
8355696
12016267
19389706
7760790
1406636
10403485
12054430
|
ESR1
|
JUN
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
11477071
17963131
10037443
16679312
|
JUN
|
IL2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
30.0
|
1.0
|
Omnipath
|
20557936
12370343
10700231
12884855
8436291
9541574
8397339
1737937
9605137
8683110
21832163
9590239
7989759
9774418
16116194
8473495
8114694
10878360
10320367
9233628
7642615
17097050
7565732
8468462
8660843
7739550
8051409
1740667
19181930
|
ESR1
|
JUN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
11477071
17317669
16713569
|
GSK3A
|
JUN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
14.0
|
1.0
|
Omnipath
|
1846781
24214991
91332050
1516134
1956339
16023596
92065884
1651323
|
CREBBP
|
JUN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
8028671
10327051
2138276
9659924
9786917
16713569
17296604
8545107
18443043
16055710
|
JUN
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
11477071
17317669
16713569
|
CREBBP
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
9192902
18765668
16417649
11113179
8616895
11782371
14766010
17400812
|
ESR1
|
PTMA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
10938099
12149645
11459795
|
RAB11A
|
RPGRIP1L
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
17574030
20399632
23253480
17646400
21273506
|
PHB2
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
15140878
17932104
26052702
10938099
12943695
|