Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
AK5 NUCKS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
CDK1 NUCKS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18491381 12413487
PPM1A SMAD2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16751101 8277589
ARPP19 PCNP â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
ARPP19 SZRD1 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
NUCKS1 PHAX â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
EP300 MDM2 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
ERCC6 PRNP â—¼   KO_UP_REGULATES ✅ + 0.88 0.88 PKG 28854368
EP300 PTMA â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 11967287 16713569 10891508
MDM2 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 9809062 11070080 16713569
ERCC6 PPM1A â—¼   KO_DOWN_REGULATES ✅ - -0.97 0.96 PKG 28854368
EP300 SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 31.0 1.0 Omnipath 21988832 23331499 9169454 12237408 10199400 11264182 7878020 8047140 12958365 19171760 11371641 16027720 17074756 17469772 21269274 15623506
PPM1A SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 18988627 16751101 23331499
ERCC6 NUCKS1 â—¼   KO_DOWN_REGULATES ✅ - -1.08 1.07 PKG 28854368
DDB2 NUCKS1 â—¼   KO_UP_REGULATES ✅ + 1.15 1.15 PKG 28854368
ERCC6 ERCC6 â—¼   KO_DOWN_REGULATES ✅ - -1.24 1.23 PKG 28854368
DDB2 DDB2 â—¼   KO_DOWN_REGULATES ✅ - -5.71 5.7 PKG 28854368