Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
ATF2 PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11243868 19948881
CREB1 BRCA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 9926942 6548521
JUN BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16229810 17434164
EP300 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23353771 23285190
ETS2 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12637547
SMAD3 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19768112 15735739
E2F3 CDK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8033208 7958856
CARM1 E2F1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16938873 0605692103
E2F1 CARM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16938873 0605692103
E2F1 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11799067
E2F1 RBBP4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18319725 12909625
E2F1 FGFR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19303924
RUNX1 EP300 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16917507 5218981
KLF1 EP300 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1017029108 21670263
STAT6 EP300 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8415882 23461825
EP300 HIPK2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 18695000 16917507
ESR1 EP300 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16704985 11279135
HIPK2 EP300 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 16917507 5218981
EP300 FOXO3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11896584
FOXM1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16809346 17875680
FOXM1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16809346
FOXM1 FOS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16965535
FOXO1 PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16670091 19289458
FOXO1 MYOD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17717603 17922034
FOXO1 KLF4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18375530
FOXO1 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 25510553 19049975
FOXO3 HIF1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18268343 0706790105
FOXO3 AKT1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 10102273 5211323
FOXO3 KLF4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18375530
RUNX1 HIPK2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 18695000 16917507
HIPK2 SUMO1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 intact 5217735 15896780
RUNX1 HIPK2 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 16917507 5218981
SUMO1 MDC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
STAT1 MDC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15784679
RUNX1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 29958106
CREB1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20864035
E2F3 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11564866 18319725
ESR1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 3677090
AKT1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17942906 9804616
MYB MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15082531
STAT1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10637230
STAT3 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22943793 15810077
SMAD3 NCOA6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
NCOA6 SMAD2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
SUMO1 PML â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17036045 5219211
PML JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9671405 10620019
PML STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12506013 16189514
SMAD2 SNAI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19389392 18618014
HIF1A SNAI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23979441 23496980
STAT3 MYOD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16713569 12947115
STAT3 KLF4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17129668
TDG SUMO1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218717 16763556
SUMO1 SRF â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12788062
SUMO1 CTBP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12769861 12679040
SMAD3 XRCC6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
XRCC6 RBBP4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
KLF15 FOS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
KLF15 SRC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PPARG KLF15 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20592862
HNF4A CDX2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22986531 19761587
GATA3 CDX2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19700764
KLF1 KLF8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18687676
PPARG MYOD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16838108 11477074
MYOD1 CCND3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10373569
SMAD3 MYOD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11711431
STAT6 STAT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 28430601 10982806
STAT1 HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19646959
SMAD2 PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21836474 21926264
CREB1 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 16862174
SMAD3 GATA3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 11790301
NCOA3 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16877447 16860316
HIF1A JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15794924 19828020
JUN AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12832543 11192249
JUN ETS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22354960
CARM1 DAXX â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
DAXX AIRE â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20185822
ESR1 PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16144913
ESR1 PPARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 16144913
E2F3 PPARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12110166 18319725
HIF1A E2F3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20308562
SRC AIRE â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
NCOA2 SRC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19305643 10454563
SRC FOS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17160021 22105363
ETS2 ETS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9334186 16189514
FOS ETS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16189514 8557686
NCOA3 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16877447 20305690
STAT6 FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18342537 11922943
STAT6 GATA3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20956546 22841009
GATA1 RUNX1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16628190
RUNX1 GATA3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16995417 12835475
RUNX1 CCND3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16287839 14747476
SMAD1 GATA3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22219353
NCOA1 CARM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14966289 15988012
E2F3 CCND3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12611887 18319725
NCOA3 NCOA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17476305 5219902
NCOA1 ESR1 â—¼   PROXIMITY 2.0 0.8 intact 5222291 17627277
ESR1 MYB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18414489
HNF1A ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 11522780
MYB PAX6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9371644 7838532
MYB GATA3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17641686
EP300 FOXO1 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
ESR1 BRCA1 â—¼   PHYSICAL_INTERACTION ✅ 0.81 0.81 mint 1204073 5215931 11244506
BRCA1 SMAD3 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 19768112 15735739
CDK2 P53 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 25241761 12064478 10747897 19556892 10348343 10884347
E2F1 CBP â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 8932363 12748276
EP300 ETS2 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 14722092 10942770 10358095 15572696
EP300 H31 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 16109717 30110629 11884585 23415232 15951563 27208796 15611041 11830591 28465257 19801601 16415179 27585400 15308690 20587414 19270680 28844863 24722339 15136563 23587423 30428346 20368990 11689448 23870121 12237408 11983172 18838386 16717280 21875947 14752096 8945521 16287840 30902546 29033323 15834423 12498683 10545121 23934153 14585496 11691934
ANDR KAT2B â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 10779504 11328859
CBP MDC1 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 19826003 16051665
CSK21 DAXX â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 32707033 33961781 21474068
CBP SRC â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 16860316 15615775 16713569 22364282
CBP CTBP1 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 15834423 35016035 16122695 34147029
ATX3 CBP â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 17885668 12297501 30994454
SMCA4 CBP â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 19448667 9584200 9443979
HXB6 CBP â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 11585930 15269212
CBP H31 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 28630323 14720327 16122695 11585930 10097092 15005629 23434580 15616580 30110629 12665567 19270680 23415232 12566391
CBP MYBA â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 16055500 9210395
IKKA P53 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 32707033 11805286 16713569 17434128
MLL1 H4 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 16878130 27248496 30804502 20452361
EP300 ATF2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 10327051 24069158
BRCA1 H4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 16628214 30804502
BRCA1 EWS â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26831064 29656893
CDK2 H4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21840486 23455922
DYR1A EP300 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30137413 23602568
CTBP1 EP300 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21102443 15834423 35016035 16122695
CTGF EP300 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
EP300 KLF8 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 35140242 20107328
EP300 KHDR1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30110629 21988832
CBP FOXM1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28387346 27542221 15024056
FOXO3 IKKB â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 15084260 25241761
FOXO3 CTNB1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 15905404 29361949
SMAD2 KAT2B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22995475 15009097 11058129 34576109
SMAD3 KAT2B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22995475 15009097 11058129 15994459
KAT2B KLF8 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 35140242 20107328
KAT2B NCOA3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 9445475 9346901 9267036
MDC1 RPB1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 14578343 22990118
MYC TDG â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21150319 26496610
MYC RBBP4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
MYC RUNX1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21150319 29467282
MYC SRCAP â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 35140242 29467282
MYC CTBP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21150319 34147029
MYC JUN â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21150319 20232342
P53 NCOA6 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19433796 32807901
ATX3 PML â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 11572863 33798946
PML PPARG â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 32929351 20211142
GCM1 SUMO1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21791615 17646165
SUMO1 ANDR â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 12177000 21242980
JUN XRCC6 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 25609649 30585729
KLF15 CBP â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 35140242 35016035
SMAD2 KLF5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19419955 18729074
SMAD3 RUNX1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 10531362 15897867
JUN P53 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31182485 25609649
JUN LYRIC â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 27956703 25609649
JUN H4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 25609649 30804502
CBP KLF8 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 35140242 20107328
KLF8 CTBP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21416054 35140242
ETS2 CBP â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 14722092 15572696 10358095
CTGF CBP â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
FOS ESR1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17317669 25303530
CREB1 SMCA4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 23671189 16675956
CREB1 NFAC2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 27637333 25609649
ESR1 KLF4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 23403292 31527615
RUNX1 CBP â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 16917507 15331439
NCOA1 NCOA3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17476305 18267973
ESR1 CTBP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 23403292 31527615
ESR1 H31 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 23403292 31527615
NCOA3 NCOA2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 18267973 11971985
CTBP1 DYR1A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 35016035 26186194
HNF1A DYR1B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 14500717 11980910
E2F3 MYBB â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17159899 12748276
E2F3 CBP â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 32945392 12748276
CBP GATA1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 12496368
EWS KHDR1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 29884807 24999758
ANDR CSK21 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33640491 32814769
HNRPL CBP â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28611215 32238831
CBP LYRIC â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 18316612 26141861
CBP PAX6 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 35140242 32238831
CBP NKX21 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 15449938 11076796 11713256
CBP BMAL1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26164627 24737000
H4 UBC9 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 14578449 30804502
CSK21 MLL1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33961781 27705803
CCND3 CDK2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 16782892 33854235 26496610 9716181 33961781 26186194 23455922
NCOA3 E2F1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 16938873 15169882 16648476
CCNA2 EP300 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
KLF15 EP300 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 35140242 35016035 23999430
CC062 EP300 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 35016035 26186194
CTNB1 EP300 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 15572674 33742100 15806138 26123998 33190089 11050151 32603375 30986748 15060161 30836930 26657156 12408825
EP300 RPB1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 16916636 33742100 9710619
AKT1 FOXO4 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 10217147 16272144 15688030 11313479 11689711
UBC9 HIPK2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 15958389 16713569 19549727 10535925 20936779 15896780 14609633
HIPK2 CBP â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 11740489 16713569
MYC MLL1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 21150319 35140242 30415952
PML SMAD3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 16189514 15356634
XRCC6 P53 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 11751391 15782130 32807901
MYOD1 SMCA4 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22068056 35140242 15870273 20195544
P53 SMAD3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 12732139 23687300 24157709
FGFR1 CBP â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22539306 25241761 19261810 15929978
NFAC2 FOS â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 27637333 18172215
CCND3 CBP â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
CCNA2 CBP â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
NCOA3 TF65 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 16331275 16456540
AIRE CBP â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 10748110 12929931
CTBP1 HD â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 16713569 11739372
SRCAP CBP â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 11581372 10347196
ANDR SNF5 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28611094 33640491 34585037
CC062 CBP â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 35016035 26186194
NEMO CBP â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 14597638 11971985
DYR1A CBP â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 30137413 23602568
TXD11 CBP â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
HD CTNB1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 32814053 20531388 17500595
SNF5 H4 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 27248496 31759698 30804502
CSK22 ZF106 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
HNF4A NCOA1 â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
HNF4A NCOA2 â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
AKT1 BRCA1 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
EID1 EP300 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
ESR1 NCOA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 0.83 0.83 Signor 11477071
NCOA1 NCOA2 â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
ATF4 FOS â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
BRCA1 CDK2 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
UBC9 ATF2 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 9488727 16713569
SNF5 BRCA1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 10943845 27591253
BRCA1 NCOA3 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 14578343 16860316
BRCA1 UBC9 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 19287951 20016594
E2F1 E2F3 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 35140242 24981860 20106982
SNAI1 EP300 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 28296173 25314079 32494626
FOXO3 EP300 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 19592618 25609649 11896584
DYR1B EP300 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 32707033 23602568
EP300 NFAC2 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 27637333 9625762
EP300 FOS â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 19064921 21937452 11287611 24069158
EP300 XRCC6 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 15023334 33742100 21988832
HIPK2 PML â—¼   PHYSICAL_INTERACTION 839.0 0.84 STRING 36370105
CBP MSX1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 11115394 10215616 16713569
MYC TF2B â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 32814053 12660246
MYC HIF1A â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 28628118 15071503 28205554
PML FOS â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 9671405 16189514
CBP SNAI1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 25314079 32494626
ESR1 SUMO1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 31527615 15961505
SUMO1 NF2L2 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 23543742 22942279
TDG P53 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 10961991 18951877
STAT1 SRC â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 9344858 16189514 14978237 10358079
SMAD2 CTNB1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 12000714 23246962 20571128 27684187
SMAD1 SMAD3 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 9111321 15761153 18729074
SMAD3 CTNB1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 12000714 22241478 20571128 21965288 27684187
SRC IKKA â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 12707358 15749833
ETS2 GCR â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 16189514 11279115
FGFR1 CTNB1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 18302981 11401320 25241761
NEMO AKT1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 20098747 20837477
DYR1B CCNA2 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 32707033 23602568
NCOA1 ESR1 â—¼   PHYSICAL_INTERACTION ✅ 0.84 0.84 mint 17627277 5222291
ESR1 NCOA1 â—¼   PROXIMITY ✅ 0.84 0.84 mint 17627277 5222291
EID1 CBP â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 24167073 15987788
MYBB CBP â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 16055500 11423988
DYR1B CBP â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 32707033 23602568
CBP CITE1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 10722728 33961781
CBP IKKB â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 14597638 25241761 11971985
UBC9 TFE2 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 10497239
UBC9 SRBP1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 12615929 16713569
TF65 P53 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 28205554 28628118 17434128
P53 CSK22 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 22653443 23455922 12393879
DYR1B BMAL1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 32707033 23602568
HIF1A STAT3 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
HIF1A KAT2B â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
ETS1 RUNX1 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
KAT2B SMAD3 â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
JUN PML â—¼   PHYSICAL_INTERACTION 848.0 0.84 STRING 36370105
CSK21 BRCA1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 10403822 16713569
STAT2 EP300 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 15154850 10464260 18678383
RUNX1 EP300 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 14752096 16917507
ANDR EP300 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 18487222 16713569 27903893 24480624 10779504 32668201 28549433 23172223 34585037 23518348
EP300 SMAD1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 10205054 20851880 22365546 16613856 10673036
HNF4A NCOA6 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 35140242 18552123 15604093 21292004
NCOA6 NCOA1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 10567404 12482968 21292004
NCOA6 XRCC6 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 10823961 12519782 30585729
TF65 PML â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 16189514 16713569 25733689 12540841
STAT3 STAT1 â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 6730629 8662591
STAT3 HIF1A â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 15735682 18985005 23604114 23991099
ATX3 SUMO1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 23382880 28275011 15952105
SUMO1 PIAS3 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 16524884 19217413 15569683 24654937
SUMO1 NEMO â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 20932475 21811235 21212807 16360037 21777808 16906147 14651848 18583959
CBP XRCC6 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 15023334 9488450
PAX6 CDX2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 10506141
KLF1 SNF5 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 11259590 11018012
SMAD2 ESR1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 20207742 11555647
UBC9 JUN â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 10788439 16713569 11877416 8733011
HIF1A JUN â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 25879517 19738058 11739718
NFAC2 JUN â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 20557936 27637333 25609649
JUN EWS â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 25609649 24999758 14550555
DAXX H31 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 28514442 25275136 33961781 23142979
UBC9 PPARG â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 26192107 15229330 19692572
PPARG NF2L2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 16189514 10930400
SRC ESR1 â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 17284441 6169640
ETS1 SRC â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 25117710 15788656
ETS2 ETS1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 16189514 9334186
AKT1 CBP â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 19995607 23434580
FOS TF65 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 16189514 18172215 10488148
CBP SMAD1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 10673036 11239394 33323411
P53 CCNA2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 16713569 10884347
MYBB RBBP4 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 17671431 25917549 27705803 33961781 24981860
NFAC2 CBP â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 19060202 9625762
UBC9 MYB â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 22910413 16713569 11779867 27150054
P53 IKKB â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 19883646 19196987
SMCA4 H31 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 20011120 15616580 26527279 34079125
TF2B TF65 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 7706261 15013781
EP300 KLF5 â—¼   PHYSICAL_INTERACTION 850.0 0.85 STRING 36370105
EP300 FOS â—¼   PHYSICAL_INTERACTION 850.0 0.85 STRING 36370105
AKT1 FOXO1 â—¼   PHOSPHORYLATION ✅ - 0.85 0.85 Signor 21798082
AKT1 FOXO1 â—¼   RELOCALIZATION ✅ - 0.85 0.85 Signor 18423396
E2F1 EP300 â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
ATF4 EP300 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 14630807 17872950 10350644 12471036 16219772
EP300 FOXO1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 15890677 24419059 25609649 18786403 11896584
EP300 NCOA2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 10490106 9920895 15731352 20448036
EP300 KLF4 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 17908689 21252119 21482710 20711222 35140242 33742100
EP300 H4 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 11163245 16096645 30804502 16109717 25728767 11884585 15951563 15611041 11830591 28465257 16415179 11689053 15308690 28844863 26625199 15136563 17982102 18397880 12499368 23587423 20368990 11689448 12237408 11983172 16717280 14752096 22100137 14612423 8945521 16287840 18418072 30902546 15834423 23934153 14585496 11691934 10607594 16332960
EP300 STAT3 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 10205054 15653507 16713569 33531691 26504087 18782771 30110629 11923478 15735682 15649887 33742100 22116549
EP300 SRBP1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 14615581 10235267 20817729 12640139 20534441
EP300 SMAD3 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 9679056 15824515 15688032 16109717 15345715 20564330 9843571 15133024 10497242 17469184 15623506 10575014 15588252 18055455 16876108 21567395 11134049 12743039 11058129
FOXO3 P53 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 18824006 14976264 25241761 27886165
KAT2B HIF1A â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 22908229 21148070 20620956 16543236
P53 SNAI1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 20385133 28067227
ESR1 STAT3 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 23874500 11429412
CBP STAT3 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 15653507 15649887 11239394
KHDR1 STAT3 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 11585385 16713569
SUMO1 SRBP2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 12615929 18403372
ESR1 STAT1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 25303530 31527615
AKT1 SMAD2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 16362038 24412244
CREB1 JUN â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 2138276 25609649
CSK21 SRC â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 21075308 31980649
SRC IKKB â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 12707358 15749833 12645577 15456896
SRC NEMO â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 23131831 15749833
ESR1 RPB1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 20308691 16957778 31527615 20348541
CBP NCOA2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 15657427 11971985 9430642 9192892 15987788
CBP PIAS3 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 28680062 14691252
CBP GATA3 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 35140242 29453984
CBP SNF5 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 9584200 9710619
EP300 KLF4 â—¼   PHYSICAL_INTERACTION 860.0 0.86 STRING 36370105
ESR1 FOXO3 â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
CCNA2 BRCA1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 25091198 16713569 9244350 10373534
CDK2 CBP â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 26186194 23602568 23455922
KAT2B E2F1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 24502362 23001041 35140242 19188449 24112038 15123636
CARM1 EP300 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 15616592 16923966 18280497 11997499 21988832 11701890 32140074 28844863 15731352
MYC EP300 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 15616592 16287840 32140074 16126174 17157259 12776737
AKT1 EP300 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 21901101 15224190 21775285 20333651 18182168 11116148
SRC EP300 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 26695438 10973497
EP300 IRF3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 12473110 11940575 9660935 11314014 20604809 9488451 21903422
EP300 NCOA1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 16713569 10973497 20368990 15688032 14722092 12208951 11113179
HNF4A FOXO1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 12519792 19740748
ESR1 FOXO3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 18312651 11435445
CTBP1 KAT2B â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 15834423 9824164 16122695
KAT2B MYOD1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 20364308 9659901 27453350 17964260 10944526 10619020 12887892 17468105
KAT2B EVI1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 20363750 11568182
KAT2B H4 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 23667505 8684459 11163245 11830591 18663001 32966758 10891493 16415179 31753913 11818576 32238831 14752096 10958685 23981651 15611041
IKKA MYC â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 33461590 21575199
PML CSK21 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 19217413 16873060 20625391 22406621
TF65 SNAI1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 19411070 25314079
IRF5 IRF3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 16189514 11303025 12138184
CBP KLF1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 21670263 11259590
CBP SMAD2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 9679056 16751102 27566588 18003620 17283070 33323411 20403362 15231748 15750622
P53 SMAD2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 25241761 19345189 12732139 19580641 23687300 25670079
JUN GCR â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 7823959 16713569 8733011 14522952
CTNB1 HIF1A â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 22865883 23246962 24650032 17220880 23671189
HIF1A ANDR â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 22865883 17426252
ETS1 CBP â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 9528793 18443043 35140242 7774816 15572696
FOS CSK22 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 9685505 16189514
P53 CARM1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 29653964 15186775
CARM1 CBP â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 17043108 11701890 15731352 12374746
CARM1 TF65 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 15616592 21483817 18280497 16497732
NCOA1 NCOA2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 18267973 9774463 11971985 9751728
GATA1 SNF5 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 35140242 11018012
PAX6 ANDR â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 19790232 21935435
RPB1 CBP â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 30994454 9710619
CBP GCM1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 35140242 20855292 16166624
CBP ZF106 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28680062 32238831
CBP SRF â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 12622724 9388250
CBP EVI1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 16713569 11568182
P53 GCR â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 11080152 16189514 11562347 16713569
EP300 STAT3 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
EP300 STAT1 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
BRCA1 MYC â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
BRCA1 MDC1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
ETS1 FOXO1 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
EP300 PPARG â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
ESR1 NCOA6 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
CTBP1 BRCA1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 21102443 16713569 10196224 31636387 11751867
BRCA1 NCOA2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 14578343 11085509 16860316
GCR EP300 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 23125313 12208951 17884810 31182584
EP300 MYB â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 20364308 11585920 29954426 15691758 35140242 10656693 25740244
EP300 SMAD2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 11371641 21988832 10199400 12237408 11264182 15623506
EP300 EWS â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 18509338 24999758 33742100 21988832
EP300 CBP â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 9267036 25314079 10899165 31753913 30110629 15598887 17970752
CTNB1 FOXM1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 22014570 26912724
AKT1 FOXO3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 21621563 10102273 25241761 21775285
MYC TF65 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 15616592 16713569 28628118 28205554 12027803
NCOA6 PPARG â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 15604093 19596656 24368734 10788465 11877444 19047629
NCOA6 ANDR â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 33640491 14645241
MYB PML â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 15194430 20802522
STAT3 PML â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 12506013 16189514
MYOD1 STAT3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 12947115 16713569
PIAS3 STAT3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16189514 11429412 21988832 9724754 18037959 12804609 20516148
JUN STAT3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 10490649 16713569
CBP SUMO1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28630323 23395904 27129204
FOS ATF4 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16189514 25241761 23661758 1827203 20102225
CDX2 CBP â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 19117933 10066780
SMAD2 SMAD1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 9111321 28628118 18729074 28205554
FOS SMAD3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 21829441 9732876
SMAD3 EVI1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 9665135 15849193
SMAD3 PIAS3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16189514 14691252
JUN ETS1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 20195357 8557686
JUN RUNX1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 11641401 11274169
JUN CSK22 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 9685505 25609649
CBP DAXX â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16287980 32545337 11799127
DAXX TF65 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28320502 17362989 25019989
ETS2 P53 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 18374905 26871468 26331536
UBC9 ETS1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 9333025 16189514 16713569
FOS RUNX1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 11641401 11274169
CBP PTMA â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16713569 11897665
IRF5 CBP â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 18836453 20935208
SMAD1 ANDR â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 17183365 23734213
NUP98 CBP â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 9858599 16651408
ESR1 GATA3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 26153859 23403292 25303530
CTNB1 HNF4A â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 12944908 25241761
CBP HNF1A â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 10777539 15598887
UBC9 ANDR â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 8798622 19692572 10383460
ANDR MLL1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 33640491 22722839
HNF6 CBP â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 12509444 10811635
CBP CSK21 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 9685505 16051665
CBP CSK22 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 9685505 16051665
CBP HXB7 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 10435624 11585930
UBC9 SRBP2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 12615929 16713569 20936779
SMCA4 RPB1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 9128241 9845365 11238380 8895581 15999204 16195385
IKKB CTNB1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 25241761 11527961
IKKB TF65 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 25241761 17962807 10521409 22689577 18519641 12842894 16046471 15489227 29084252
IKKA CTNB1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 11527961 12589056
CSK22 MLL1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 27705803 33961781 26186194 32707033 23455922
EP300 MYOD1 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
STAT1 STAT3 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
EP300 KAT2B â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
SRC STAT3 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
CARM1 NCOA3 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
AKT1 EP300 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
CARM1 EP300 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
NCOA1 STAT6 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
ATF2 NCOA6 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 14734562 11302752
TF65 BRCA1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 12700228 21908405 16713569
RBBP4 BRCA1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 10220405 16713569 26831064
CBP BRCA1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 10655477 11782371 16713569 16417649 9926942 12700228 16860316 9443979
MDC1 BRCA1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 21622030 19766185 15569676 12611903 17525332 12607005 29656893
ANDR BRCA1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11085509 16713569 11016951
RPB1 BRCA1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 14506230 18197258 10725406 16713569 12955082 22990118 25184681 27583302 29180510 29513652 15886201 11504724 9159119
STAT1 BRCA1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 10792030 16713569
BRCA1 SUMO1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 26831064 18025037 20016594
E2F1 CDK2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 8458319 7969176 9199321 1530885 11245432
P53 E2F1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 8557038 11739724 24076372
CREB1 EP300 â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
KAT2B EP300 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 8684459 12888487 9267036 12419806 21413932 22384255 20870727 33051058
EP300 STAT6 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 10454341 17237818 23461825
EP300 PAX6 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 35140242 10506141
EP300 CITE1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 10722728 16864582 33961781
EP300 KLF5 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 14612398 19419955 15668237 35140242 16102021
EP300 HIPK2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16917507 29170424
EP300 PTMA â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11967287 10891508 16713569
AKT1 FOXO1 â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
FOXO1 ESR1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 22266855 11435445 11353774
SMAD3 FOXO3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15084259 24920680 21532621
FOXO3 CBP â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 22474372 25609649 15126506
CBP FOXO4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 10973497 20874444 15126506
HIPK2 DAXX â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 19465479 14678985 23536002
KAT2B MYOD1 â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
KAT2B H31 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 23667505 11830591 18663001 10891493 16415179 15005629 10545121 31545241 15616580 14752096 23415232 15611041
KAT2B NCOA1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 9445475 9296499 9223281
KAT2B TFE2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15507449 12435739
SNF5 MYC â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 10319872 14559996
MYC CBP â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 35140242 16878156 12776737 29467282
MYC PML â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17146439 15735755 21150319 32592588 30415952
MYC XRCC6 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17314511 30415952 29467282
MYC P53 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 21150319 30415952 28628118 28205554
NCOA6 ESR1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 10866662 16794079 10567404 10681503 11773444 26487511
NCOA6 GCR â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28611094 31182584 10567404 10866662
UBC9 PML â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 9885291 18691969 17081986 27030546 32001251 21988832 30292834 27903803 30935967 29773808 15809060 29535160 12641448 15561718 22155184 29599493
PML JUN â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15626733 9671405 16916642 10620019
NCOA1 STAT3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17471507 11773079 16713569
SUMO1 P53 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16189514 15144954 23543742 22214662 23604351 15017387 12917636 16732283 18583933 11867732 10961991 10562557 17369817 20972456 19246003 19684601 23825024 10788439 15242646 23150668 15327968 15576338 16122737 17060459 21316347 16713569 15931224 20861261 23772552 32807901 20534433
TDG ESR1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 12874288 16282588
H31 XRCC6 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 20080577 29568061 21187428 33961781 34079125 26527279 25281560 20504901
ATF4 CBP â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 10350644 25241761 11564156 9295363
ATF4 NF2L2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 32911434 16189514 23661758 26700459 11274184
JUN MYOD1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 8380166 1310896 16713569
STAT2 STAT1 â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 24065129
STAT1 CBP â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 25451029 16481475 25733689 15695802 8986769 19915063 9037008 15894584 10848577
SMAD2 JUN â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11371641 20195357 10220381 25609649
HIF1A SMAD3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 12228247 28471448 11486006 14741200
SMAD3 GCR â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16189514 10518526 12902338
NCOA1 JUN â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 10847592 10567404 16713569 9642216
JUN ESR1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17317669 11477071 16713569 23747343
DAXX ETS1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15247905 16861237 10698492
PPARG CBP â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15556564 22070604 17704298 10339548 16713569 19596656 35140242 11877444 30595551 17312272 10848596 10622252
HIF1A P53 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15629713 16189514 11593383 9537326 16713569 12124396 31467278 12606552 10640274 27345397
AKT1 IKKA â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 25241761 17962807 10485711 15710601 15800029 10485710 11278366
NCOA1 FOS â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 18511550 10847592 9642216
GCR CREB1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16189514 16713569 7621901 20203101 8449898
CREB1 P53 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 10848610 21295542 25241761 16611888
STAT6 CBP â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15695802 10454341 31554795 11574547
NCOA3 CARM1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16923966 17043108 15383283 26267537 18511550 16938873
P53 ESR1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16713569 26556313 10766163 17545634 21761334
ESR1 TF65 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 19350539 31527615 7651415 16497877 17932106 16331275
NCOA3 NEMO â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16051665 11971985
SRBP2 HNF4A â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 20926756 12855700 16713569
H31 RBBP4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 20080577 27098840 16728976 19410545 14718166 31435636 11850410 29263092 19410544 33961781 26527279 16622419 29568061 19498464
RBBP4 CBP â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 10866654 16713569
ANDR SMCA4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 18487222 19762545 33640491 28611094 14966121 34585037
UBC9 CBP â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28630323 22227369 28680062 23395904
KLF5 CBP â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 18500350 35140242 16713569 12682370
SRBP2 CBP â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16713569 16799563 8918891 25368385
CBP TF2B â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11864601 10196247 7913207 11782371
CBP SRTD1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 12736710 16098148
CBP SH3G1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17891136 15752756
CBP MLL1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 12205094 16799563 11259575 17707401
CBP GCR â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16713569 9649342 9590696 20018896 31182584 25511704
CBP HD â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15994095 16713569 11607033 16456924 11264541 10823891 17500595 30994454
SNF5 P53 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16713569 11950834
CSK21 P53 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15358769 25241761 23443559 11709713 10951572 11883897 10747897 12628923 10348343 12393879 24725084 22975381 10884347
SMCA4 PAX6 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 35140242 16675956
SMCA4 CTNB1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 19571879 11532957 29463646
CCNA2 E2F1 â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
EP300 NCOA3 â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
ATF2 FOS â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
PIAS3 STAT3 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
CBP ATF2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16303757 17296604 11564156 9786917 31964530 9659924
JUN ATF2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 8027667 20102225 28514442 16511568 23661758 15546613 26496610 2320002 20195357 10327051 1827203 9445037 20511396 10207054 25609649 33961781
FOS ATF2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 1828107 25416956 32296183 16511568 23661758 20195357 33961781 1827203 26186194 25609649 20102225
ATF2 CCNA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9511728 10777595 7843287
SMCA4 BRCA1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15034933 16713569 23438604 10943845 26831064
ESR1 BRCA1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19887647 1244506 11782371 15674350 29367421 27977889 17392432 16860316 10334989 16260778 11244506 16061635 12400015 17505062 20060929 25499220 16713569 31527615 11493692
EP300 BRCA1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21102443 19887647 10655477 11782371 16713569 21212407 22787115
JUN BRCA1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12080089 25609649 16713569
P53 BRCA1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 14710355 16713569 21742769 15571721 26140185 9926942 9582019 14636569 14978302 16677609 18501503 9482880 19509300 16969499 31073355
MYC BRCA1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12646176 11916966 16713569 20215511 9788437 30415952 14612409
AKT1 BRCA1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21242970 10542266 20085797 19074868
CDK2 BRCA1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 31270457 16713569 10373534 9244350 8764100
E2F3 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17106239
CDK2 EP300 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 33961781 26186194 10330164 23455922
CDK2 NCOA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10660621 21550420 17570479
E2F1 CCNA2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 8458319 7969176 12501191 35140242 9724724
E2F1 FOXM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21518729 22802261
E2F1 CCND3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12611887 16300731
E2F1 FGFR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19303924
E2F1 NCOA3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16916939 23660594
E2F3 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14576826 10766737 18319725
EP300 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10753885 15123636 15126619
E2F1 PPARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15711575 12110166 18319725
E2F1 MYB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10567569 8137237 18319725
E2F1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11564866 18319725 90001421
EP300 IRF3 â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
EID1 EP300 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11073990 24167073 11964378 11073989
EP300 NCOA3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16923966 10655477 9267036 23065768 16227615 20368990 11823864 10490106 25728767 33589584 10866661 15145939
EP300 TFE2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15934135 14752053 12435739 22207202
EP300 MYOD1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20364308 12665587 20037778 17964260 35140242 10944526 9862959 9001254 8621548
EP300 P53 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 9809062 15295102 21471221 26229107 15337767 23010591 18485870 15558054 22266186 15509808 26625199 9194564 23402884 23870121 17438265 16959611 12690203 17906639 24821727 15664194 21187340 33196849 17977830 11804596 25288747 15186775 18612383 23796514 19234109 27818144 19339993 24157709 9652736 28757384 12499368 17452980 9891054 23880760 31167125 15542844 22013068 16713569 9288740 17189186 11782467 16543236 23329847 10942770 26302407 23307557 22074660 19218448 19217391 10601022 16024799 16782091 12501250 11433299 22731250 23728348 10518217 9194565 25651062 12724314 14612423 16611888 19805293 18243116 32807901 29706626 20234175 16678111 14759370 25867071 25156994 11907332 16438982 16135789 11070080 11359905 25753752 16537920 9744860 18391200 15965232 10490106 16928824 12162806
EP300 JUN â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 27956703 21268080 21937452 24069158 11689449 14630807 11980644 10327051 12437352 12471036 24636898
EP300 PPARG â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11500849 17468099 10944516 14701856 11287611 19596656 32603375 11877444 12040021 10075656 30595551 22787115 12479814
EP300 ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19887647 11782371 12738788 25728767 11867769 12479814 23065768 15308690 20388208 14761960 22227247 8799122 20348541 23403292 12714702 11581164 16713569 19838210 18765668 16645043 30418174 12574227
EP300 HNF1A â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 35140242 15598887 11978637
EP300 TF65 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11585920 25074812 15171256 11533489 16291753 23999430 16135789 12403783 12456660 11567019 9096323 25400040 20154269 17982102 18397880 18280497 12419806 21187066 12471036 23811396 16713569 10235267 15192014 17692505 20333651 21483817 12960163 29706626
ANDR FOXO1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17202144 12482965 16713569
CBP FOXO1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 10973497 24419059 16154098 25609649 15220471
FOXO4 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11896584 11313479 11689711
CREB1 FOXO4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 15126506
SUMO1 HIPK2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15958389 16253240 21145359 10535925 15896780 21192925 24637324 14609633
HIPK2 P53 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16212962 25313037 16713569 17349959 11925430 34133717 11875057 11780126 15896780 11740489 22110707 21057547 25961923
HIPK2 SMAD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 12874272
MYC KAT2B â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15572685 35140242 12660246
KAT2B P53 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19680552 17977830 16678111 15965232 20589832 10891493 12068014 17189186 9891054 10490106 16537920 9744860 12501250 14614455 16959611
KAT2B CBP â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 8684459 11864601 9267036 9710619 9445475 9687573 9687513
NCOA1 KAT2B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12163591 10809234 10777539
KAT2B HNF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10777539
MSX1 MYOD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15192231 10529415 7664340
SMAD2 MYC â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11804592 28628118 28205554
MYC SMCA4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11839798 28628118 17353931 29467282 28205554 30415952 14559996
MYC RPB1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17314511 23079660 12660246 29467282
SMAD1 MYC â—¼   DOWN_REGULATES ✅ - 3.0 0.9 ACSN 15576399 22290435 22761862
MYC RBBP4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
MYC AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16846534 16489011 18562319
MYC STAT6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC KLF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC IRF3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
NCOA6 SRC â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 10847592 11158331 10567404 12482968
NCOA6 CBP â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11158331 10567404 10866662 12482968
TDG PML â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15569683 16189514 17060459
CBP PML â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16713569 12234245 17239008 10077561 10610177 25733689 12622724 12142048
P53 PML â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16189514 25241761 22869143 16713569 12915590 14976551 16007146 20972456 12006491 15375079 11025664 11704853 11080164 21057547
SUMO1 PML â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11948183 16189514 9885291 19015637 21305000 23028697 28851805 23604351 15017387 22155184 21057547 19380586 24190887 20826694 20972456 23830076 17027752 24654937 25497731 9756909 21779164 31879127 17081986 18625722 8806687 17081985 17344210 19217413 17036045 18474224 9452416 20188669 16501610 22406621 22875967 9427741 15561718 21098080 11080164 11160742
STAT1 PML â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21115099 15519999 22589541
STAT2 PML â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17062732
PML SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 15356634
TF65 STAT3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16189514 16713569 19345327 14593105 23335796 12057007 31802034
GCR STAT3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 26508788 9388192 16189514 16713569 25202013 14522952
SRC STAT3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16189514 21573184 15313931 11294897 8657134 18070987 10918587 12244095 19372587 12626508 8626374 14551213 16713569 8272872 11350938 9566874 12576423 11940572 15735682
ANDR STAT3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12804609 11322786 16713569 11751884
STAT3 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21546410
STAT1 SUMO1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 10805787 12855578 18031232
SUMO1 CTBP1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 20176810 20098713 12679040
SUMO1 TDG â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16189514 10961991 21284855 16763556 16524884 15959518 24637324 11889051 17060459
ESR1 SUMO1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15961505 24119295 18404132
TDG CBP â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11864601 24748645 28680062 24394593 24532795 17060459
TDG ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12874288 17129768
EID1 XRCC6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
IRF3 CBP â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12473110 17126870 17015689 23746807 15107417 21903422 14668346 11940575 9660935 20581830 17296604 10082512 17761676 15582653 16154084 25733689 15502848 18309294 17138826 10521456 23824799 9566918 11314014 9488451
ATF4 JUN â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 25241761 1827203 20936779 23661758
JUN CDX2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20351696 9926923 24953186
CDX2 KLF4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11521200 23202735
MYB KLF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20686118
GATA1 KLF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20564185 8195185 18487511
CBP MYOD1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11463815 16713569 20037778 10944526 2176177 35140242 12154097 9238849 9001254
MYOD1 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10973962 16901893 21689744
STAT2 STAT1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 8621447 8605877 28514442 26966684 10446176 31836668 17923090 10490982 9724754 24065129 15825084 35140242 33961781 12048190
STAT1 STAT2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16918696 19122651
SMAD2 SMAD3 â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
SMAD2 CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 9689110
SMAD2 SMAD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18729074 9111321
AKT1 SMAD3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16362038 25241761
SMAD3 ANDR â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11707452 11280774 12226080 16713569
SMAD3 JUN â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 10903323 11306568 10220381 9732876 21829441
SMAD3 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12374795 10022869
CBP JUN â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16713569 2138276 17296604 9786917 18443043 10327051 8028671 9659924 15994313 16055710
CSK21 JUN â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 1516134 9685505 12628923 25609649
ANDR JUN â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 9211894 33640491 16713569 8798722
JUN NF2L2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 32911434 20232342 12805554 9872330 20194533
JUN ETS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 1945412 8247540
UBC9 DAXX â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17081986 18691969 15087395 16713569 23395904 12150977 21474068 11112409
ANDR DAXX â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15572661 27671201 32694250 15350595
GCR DAXX â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12595526 17081986 14978255
DAXX H4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 12140263 21724829 19862764 27248496 25416818 33961781 24981860 23075851 29084956 32545337 23142979
NCOA2 PPARG â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11500849 23178929 15026545 10944516 19596656 11877444 17513608
NCOA3 PPARG â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11500849 23178929 10944516 15604093 19596656 35140242 11027271 11877444 15888456
PPARG NCOA1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 23178929 17704298 10944516 15604093 19596656 17312272 10731636 16373399 30595551 17011503 17468099 22070604 15026545 10339548 10347167 9121466 9041124 23975195 20717101 10848596 9744270 17449869 11500849 16713569 11027271 11877444 15888456 17513608 30813326
SMAD1 PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23071089 12589053 16580992
HIF1A PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18461556 19490906 11879638
PPARG FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10678274 23657115 18059282
HIF1A CCNA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21029732 16399861 19304911
ANDR SRC â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 24728074 15062576 11032808 15466214 15027889
SRC ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 24498420 14766010 15604093 11013076 27420286 29720121 12736255 18451880 15140878 23065768 17043237 17627277 7539106 11032808 17363140 20935677 14963108 11564893 12630920 22328528 15020686 15784253 17921256 24051437 10454579 17400812 17284441 16957778
ESR1 SRC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20160136 20460377 22865929
NCOA3 SRC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19305643 12650696 17671194
NCOA1 SRC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19305643 17400812 17495236
STAT2 CBP â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 10464260 8848048 33961781 28707474
ETS1 MYB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 7848925 8999884
AKT1 ANDR â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 18332867 28708672 16210317 11156376 11404460
CBP FOS â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 35140242 11782371 16055710 10487758
NCOA1 STAT6 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 14993689 12138096 18267973 15695802 33961781 11574547 14757047
STAT6 KLF4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22378047 25934862
STAT6 GATA3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17312100 12947222
KLF4 CBP â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17908689 10666450 21482710 35140242 21539536
NCOA3 CARM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14966289 22977234 15988012
NCOA2 CARM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14966289 16344550 15988012
NCOA1 ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20608937 15604093 12738788 11003650 11250900 18451880 11867769 15140878 16282588 11165056 11376110 17627277 14715875 10731636 9259327 17363140 11113179 16606617 12630920 9121466 10760302 26487511 23975195 11682626 12714702 9192902 9192892 23874500 11358671 16713569 11014206 10454579 9773983 12554772 9427757 10598586 10409727 9774463 12574227 16957778
NCOA1 ANDR â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15256534 16713569 10731636 33640491 12612084 23975195 12163482 10567563 17353003
NCOA1 CBP â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15615775 16713569 11971985 12482968 12163591 9445475 11003650 8616895 9192892 14722092 16860316 11113179
NCOA1 GCR â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11266503 12917342 16713569 16606617 10659697 16423881 10731636 9590696 12118039 28611094 12569182 31182584
SMCA4 ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 18451880 9099865 11003650
CBP ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11782371 16417649 18765668 17400812 14766010 27420286 23403292 9192902 8616895 11113179
NCOA3 ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 26153859 20392877 15383283 14766010 25728767 21182203 15145444 18484708 11376110 14966289 9346901 20181721 26166704 16331275 28844863 11389589 11050174 12630920 19491275 17158759 23403292 12714702 17646391 9192892 11353774 16923966 18645020 16713569 30418174 10490106 9765300 12554772 26487511
IKKB NCOA3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15383283 16051665 16135815 11971985
GCR NCOA3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11266503 12917342 18160712 28611094 31182584
NCOA3 IKKA â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15808510 15383283 16051665 11971985
NCOA3 ANDR â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21047772 16713569 11747336 16951154 15563469 33640491 14966121 10965917 32668201
HNF4A CBP â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 18552123 16713569 10882110 9434765 10085149 9792714
HNF4A P53 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 16713569 35140242 33961781 11818510
CBP GLI3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 10075717 32238831 17000779
CBP ANDR â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12810069 16713569 9822653 20541699 33640491 9482849 15691881 34585037
ANDR CTNB1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 22865883 21885566 16713569 12799378 11792709 15060161 11916967 12944908 22187462 21741601 12588987 10987273 15256534 14593076
SRBP1 CBP â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16799563 8918891 10235267 9651391 9765204
NF2L2 CBP â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 18241676 19273602 11683914
TFE2 CBP â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 22387215 22207202 15507449 12435739 32098872
CBP H4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11163245 14720327 10097092 28680062 15005629 32238831 12665567 24361270 12566391
CBP EWS â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12459554 32238831 24999758 16713569
CBP MYB â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16799563 11073948 23980173 35140242 12196545 14761981 16055500
CBP P53 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 22084066 23908595 27618436 19234109 20962272 14759370 10551785 18485870 19166313 10473588 12426395 12154097 18753379 14722092 19357310 10848610 28630323 10648616 19880525 25314079 9194564 15632413 16537920 17434128 10196247 10823891 26976603 25451029 19220000 16713569 21390126 19805293 9288775 11782467
UBC9 P53 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16189514 22214662 10380882 31467278 10961991 10562557 21829513 30217970 19684601 10788439 12565873 15327968 11853669 23202365 16122737 17060459 32780723 8921390 16713569 17709345 23772552 28784659 18624398 16442531
SMCA4 P53 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11950834 19448667 21900401 18303029 17666433
P53 HD â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16713569 32814053 15383276 10823891
SMCA4 GCR â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 9128241 12917342 10688647 9590696 17387179 28611094
CSK22 CSK21 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 19011756 26496610 30279146 27705803 25519132 33961781 24981860 26186194 25852190 32707033 23455922 26344197
NEMO IKKB â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 23986494 20211142 16611882 20098747 15802604 30913450 16547522 14743216 18450452 10980203 19666608 23131831 21455180 16906147 15184390 24469399 19820708 18462684 31145594 15749833 28249776 24618592 10968790 19422324 30500824 23104095 16938294 31932854 18949366 20167598 16603398 25286246 18583959 24266532 22605335 27426725 26500060 19706536 19365808 18037881 20932476 30404796 16319058 9751060 23506214 25979343 17363973 25400026 22990857 12657630 30561431 12459277 12486103 16583354 29474632 32024699 11971985 11057907 18266467 12133833 24240172 18266324 23016877 21423167 17977820 33961781 20368414 32731169 28514442 25304104 18207244 12612076 19959994 25852190 21903422 29111346 26496610 19656241 17000764 21803029 16497931 20434986 16129692 17568778 11864612 22099304 19815509 17693255 27929056
IKKA TF65 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 14743216 8246997 21903422 22689577 18519641 32232831 12842894 16382138 17434128 16046471 15489227
MLL1 H31 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 29897600 31544921 20541251 24235145 20452361 31485071 12453419 34079125 24680668 16878130
BRCA1 ESR1 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
EP300 MYB â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
CCND3 CDK2 â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
FOS ATF2 â—¼   PHYSICAL_INTERACTION ✅ 0.91 0.91 mint 25609649
KAT2B RPB1 â—¼   PROTEIN_INTERACTION 0.91 0.91 HIPPIE 18710935 9710619
HNF4A HIF1A â—¼   PROTEIN_INTERACTION 0.91 0.91 HIPPIE 12097158 14741200
EP300 JUN â—¼   PHYSICAL_INTERACTION 911.0 0.91 STRING 36370105
ESR1 SRC â—¼   PHYSICAL_INTERACTION 921.0 0.92 STRING 36370105
DAXX PML â—¼   PHYSICAL_INTERACTION 926.0 0.92 STRING 36370105
SUMO1 JUN â—¼   PROTEIN_INTERACTION 0.93 0.93 HIPPIE 10788439 15469925 11867732
TF65 PPARG â—¼   PROTEIN_INTERACTION 0.93 0.93 HIPPIE 30398029 33756273 14587029 23250430 18556801 23684777 17312272
ESR1 NCOA3 â—¼   PHYSICAL_INTERACTION 929.0 0.93 STRING 36370105
CBP IKKA â—¼   PROTEIN_INTERACTION 0.93 0.93 HIPPIE 17434128 14597638 11971985 12789342
EP300 ESR1 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
AKT1 FOXO3 â—¼   PHYSICAL_INTERACTION 939.0 0.94 STRING 36370105
HIPK2 MYB â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 15082531 16055500
CBP SMAD3 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 19589780 27566588 10497242 18003620 17283070 15467747 33323411 15849193 15990875 15750622
HIF1A BMAL1 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 25416956 9576906
EP300 SMAD3 â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
AKT1 FOXO1 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 10358075 25241761 10358014 16076959 31844113 18786403
SUMO1 HIF1A â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 20026589 15876874 24434214 20661221 15465032 17938407
SRC CTNB1 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 23246962 11279024 22056988
H4 RBBP4 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 28514442 27098840 30804502 12628926 19862764 8858152 29104064 27248496 9427644 33961781 24920672
NCOA2 PPARG â—¼   PHYSICAL_INTERACTION 954.0 0.95 STRING 36370105
HIF1A EP300 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 17382325 5219810
CREB1 EP300 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 12665587 21268077 10506141 21212407 11313407 7870179 17476304 22787115 26944191 33846793
NCOA3 CBP â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 9267036 16713569 11971985 17043108 16227615 9346901 15383283 11823864 9445475 21632823 33589584 9192892 8616895 26267537 11076796 21914189
PIAS3 TF65 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 15140884 16189514 22649547
CBP CTNB1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 26123998 16476742 33190089 11973335 23273993 19223551 28648376 30836930 18347063 26657156 21751375
TF2B RPB1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 17643375 9159119 14963322
HIF1A EP300 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 15280364 19589782 16543236 11823643 22807441 19666581 16189267 18047470 15342390 12042299 19680224 22735262 23448368 26135796 23618863 14691445 19696166 11959990 27320910 16847340 24821806 22789427 17906695 8917528 20620956 20000859 15261140 16081065 12778114 22219185 15154850 25192544 22075993 19071119 22908229 19940151 21187066 24421387 23880760 11940656 23966271 26826385 26944191 12588875 23746844 11063749 27808477 19074848 20603618 15155277 18268343 20829524 21148070 12914934 17502379 22684029 17382325 26751287
DAXX PML â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 30292834 21482821 21474068 10669754 14517282 12529400 20972456 15350595 10545115 21779164 11244500 32545337 17081986 12595526 15710327 21840486 17419608 12150977 24637324 10684855 17360386 10525530 23222847
SUMO1 DAXX â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 11948183 17081986 23395904 18583933 30958586 16475184 12150977 20972456 20927612 25409927 21816224 28851805 21474068 11112409 22578841 31879127 19465479 21383010
MYOD1 TFE2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 10915743 9050988 35140242 9184158 9242638 1649701 9001211
HIF1A CBP â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 22219185 15154850 21602890 15615775 16543236 18426857 15527772 11959977 9887100 19880525 27934968 16579968 8917528 11983697 17382325 10202154 25517638
NCOA2 ESR1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 14766010 12612084 11250900 12837248 17697320 11376110 9430642 11265755 20348541 19460354 18499756 12630920 12714702 9192892 15657427 11014206 16645043 11937504 12554772 26487511 9774463
NCOA2 GCR â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 11266503 12151000 9590696 28611094 31182584 9920895
NCOA2 ANDR â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 12810069 10935543 16713569 15563469 33640491 10454556 12612084 14966121 12588987 15684378 9717843 14593076
KHDR1 CBP â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 17891136 16713569 32238831 28648376 12496368 15021911
CBP TF65 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 12163591 15140884 16291753 14597638 17362989 17962807 18241676 17296604 9096323 12789342 25314079 9548485 11931769 9806899 10542243 17434128 25733689 15806143 16713569 10235267 10454579 17138826 21483817 9659924
NEMO IKKA â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 11080499 21703539 23986494 16611882 25304104 20098747 18949366 18207244 11877453 30913450 12612076 19959994 21903422 22605335 14743216 10733566 10980203 22547678 19666608 23131831 26496610 17363973 21455180 22990857 12244103 26500060 18079694 30561431 12459277 17000764 15184390 12486103 16583354 24469399 18462684 11485410 25355947 11057907 32707033 16497931 15749833 20434986 18266467 32935379 17568778 11864612 17244613 24618592 28249776 23016877 12138192 19815509 17977820 10968790 20368414 30404796 33961781 16938294 16319058 9751060 17728323 27929056 32731169
IKKA IKKB â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 25241761 11080499 9914500 9346241 9346485 11585904 21784860 25852190 25748427 12210728 21903422 14743216 10733566 12244103 9346484 12486103 11971985 21575199 11057907 32707033 16286467 16129692 20434986 11864612 16713569 23016877 20932476 10968790 30500824 17693255 33961781 9751060 16319058 9721103
SUMO1 TDG â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
CDK2 CCNA2 â—¼   PHOSPHORYLATION ✅ + 0.97 0.97 Signor 10652300
PML SUMO1 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
DAXX SUMO1 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
ATF2 JUN â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
NCOA1 PPARG â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
ESR1 NCOA1 â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
FOS JUN â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
CCNA2 CDK2 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 8475101 28514442 16431923 33854235 11940657 10559988 15189033 17361108 16290148 14681455 17254966 8662825 25852190 15557281 23455922 19483727 18471975 11141566 10924145 15828833 21241890 19631451 11377199 18177895 8684460 26496610 9716181 12853968 11907280 23602568 9724724 15647383 14656438 19773423 12941338 15239650 24302728 25669885 15890360 7630397 8756328 8397207 21447625 22231403 20733051 9660939 24358021 12044161 33422522 11983168 33961781 26186194 7553852 16209941 12244298 9380407 8463339 15455144 10930425
STAT1 STAT3 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 16007122 11722592 16189514 25241761 28514442 26966684 8662591 11594781 31462771 35140242 33961781 25609649 12070153
UBC9 SUMO1 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 16189514 21518904 22411991 25416956 21949651 17956732 32296183 18691969 16732283 18211895 10961991 21212807 9497385 26496610 24352468 11735126 19684601 17491593 14673145 26264872 9920803 17353931 19785004 23871147 9353268 17938407 16524884 26344197 12924945 16494873 8921390 16713569 18264111 21174150 15931224 25502805 18359863 20501649
DAXX P53 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 25241761 16713569 14557665 12954772 15364927 16845383 32545337 21482821 23038753 27626385 28875283 12482984 15339933 21134643
KHDR1 SRC â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 10635328 16713569 7537265 10467411 11960376 1374686 15190072 22745667 16169070 8766817 18606683 1545818 9038356
CBP CREB1 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 18599546 9786917 20403362 23671189 12196545 7870179 17476304 9413984 11259575 15073328 27789289 12198160 7913207 15691881 20541704 8413673 10848610 12933667 16799563 8663317 11564156 11313407 15585582 17209043 17707401 9829964 8028671 10866654
ESR1 NCOA2 â—¼   PHYSICAL_INTERACTION 989.0 0.99 STRING 36370105
CTBP1 EVI1 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 11328817 28514442 11313276 31041561 16713569 33961781 35016035 26186194 11568182 30462309
H31 H4 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 28514442 8598932 25416956 30804502 23319141 27248496 16622419 19498464 20080577 14578449 29568061 21724829 19410544 26527279 18571423 25533843 19766566 22828868 14718166 20739937 33961781 20498094 34079125
TF65 GCR â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 16189514 7659084 16713569 10995388 25202013 8290595
EP300 HIF1A â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ATF2 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 10366004 10327051 8530413 12052888 15068801 12751796 9502786 9141200 9252389 11238729 12903123 19255142 11736649 16511568 9819389
ATF2 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 31.0 1.0 Omnipath 25609649 20102225 15546613 2320002 10327051 1827203 9445037 26496610 20195357 16511568 20511396 10207054 8027667 23661758 31515488 18641343 1828107
BRCA1 E2F1 â—¼   PHYSICAL_INTERACTION 24.0 1.0 ACSN 10884389 11877377 12496474 15175241 15220350 15279786 15459660 16581787 17218262 17303408 17660363 17713585 18458534 18590585 18660752 19525936 19793801 20029420 20376879 21060331 21337561 24254977 7575488 7935440
BRCA1 E2F1 â—¼   SHARES_COMPLEX 24.0 1.0 ACSN 10884389 11877377 12496474 15175241 15220350 15279786 15459660 16581787 17218262 17303408 17660363 17713585 18458534 18590585 18660752 19525936 19793801 20029420 20376879 21060331 21337561 24254977 7575488 7935440
BRCA1 E2F1 â—¼   ENZYMATIC_REACTION ✅ 24.0 1.0 ACSN 10884389 11877377 12496474 15175241 15220350 15279786 15459660 16581787 17218262 17303408 17660363 17713585 18458534 18590585 18660752 19525936 19793801 20029420 20376879 21060331 21337561 24254977 7575488 7935440
MDC1 BRCA1 â—¼   DOWN_REGULATES ✅ - 13.0 1.0 ACSN 12607003 15279786 15459660 17303408 17660363 18001824 18006705 18087291 18583988 18590585 18678890 7575488 9407949
CREB1 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9528858 19882681 18160048 23447579 11704836
CTBP1 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 20818429 21681822 23303449
E2F1 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 10660629 23285190 18660752 19466541 17106239 20068145 23108140
MYC BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 12032322 19882681 20940401 10375022 21668996 11916966 12646176 11983916
E2F1 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 9244350 18660752 18319725 11278247 12697828 16713569 12909625
CDK2 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 8764100 10373534 10550055 19683496 16713569 26719576 15212693
AKT1 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 17428466 20832017 20085797 21242970 17570479 10542266
MDC1 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 18087291 17525332 12607005
BRCA1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 11244506 12400015 15674350 10334989 16713569 11493692
CCNA2 CDK2 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
MYC CDK2 â—¼   PHYSICAL_INTERACTION 34.0 1.0 ACSN 11274345 11283614 12545156 14536078 15147722 15155580 15279786 17055429 17303408 17550342 17558397 17660363 17873522 18590585 18636226 19887899 20027199 20237412 20551172 20581311 20713526 20818389 21406394 21733352 2191300 21919891 22067385 23140366 23869868 24954210 25002027 28536364 7575488 9618481
MYC CDK2 â—¼   SHARES_COMPLEX 34.0 1.0 ACSN 11274345 11283614 12545156 14536078 15147722 15155580 15279786 17055429 17303408 17550342 17558397 17660363 17873522 18590585 18636226 19887899 20027199 20237412 20551172 20581311 20713526 20818389 21406394 21733352 2191300 21919891 22067385 23140366 23869868 24954210 25002027 28536364 7575488 9618481
CDK2 SMAD3 â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 ACSN 10197981 11283614 12193595 14536078 15147722 15241418 15279786 16156666 17055429 17303408 17660363 18590585 18636226 20027199 20713526 2191300 28536364 7575488
CDK2 E2F1 â—¼   ENZYMATIC_REACTION ✅ 27.0 1.0 ACSN 12086603 14536078 14988723 15136767 15147722 15175241 15279786 15798197 16713580 16805667 17102137 17116885 17296725 17303408 17384638 17582221 17660363 18469862 18590585 18636226 18995830 19282663 19342888 19622404 19793801 20051983 7575488
AKT1 CDK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18354084 29665367
CDK2 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 8386367 27653698 17081983 19966300 18669648 29896817 17570479 20713526 17558397 15103331 22348395 20445224
CDK2 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 34.0 1.0 Omnipath 10197981 15241418 19218245 25241761 15520018 20068231 17099224 16156666 16189514 19413330 14512875 12193595 15212693 19114991
CDK2 CDX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 16027724 17570479
CDK2 FOXM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 28387346 15024056 19737929
CDK2 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 7575488 18590585 9315635 17303408 17570479 25101673 16213134 17660363 12006580 11420722 15279786
CDK2 FOXO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 21.0 1.0 Omnipath 21106439 19652536 7575488 18590585 17522590 17303408 27035875 19473886 24948874 15677884 15279786 23029264 19124971 17660363 17038621 20148668
CDK2 CCNA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 81.0 1.0 Omnipath 8756328 7553852 11377199 17145710 23602568 11983168 12044161 19483727 12853968 16209941 8397207 15455144 19631451 8475101 24358021 15557281 8684460 12941338 15647383 15890360 21447625 9380407 26496610 11141566 25852190 15189033 14656438 20733051 21241890 10652300 25669885 12244298 26186194 10930425 9660939 10477583 24302728 15239650 19773423 8463339 16290148 10924145 11907280 17361108 17254966 8662825 15828833 18471975 9724724 7630397 10559988 9716181 11940657 23455922
CDK2 RUNX1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 25914884 17570479 16046550 17015473
CDK2 MYOD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 21902831 10942602 25751651 25552934 22179841 17570479 10082583 26825227 10764802 9710583
CDK2 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 10428798 22431515 23390529 17570479 23770852
ESR1 E2F1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22791811 20215421 12697671 10446910
E2F3 E2F1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 14576826 7958836 12063292
E2F1 MYB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 10567569 7929342 7565760 15867358 16299810 8137237
E2F1 PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15711575 12110166 20971808
E2F1 IRF3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19826915 24535579 22464952 21225257
E2F1 CCNA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 7623816 11264255 9178900 20580656 14681231 10594784 24335704
E2F1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 8208548 2721961 7753559 11705881 24038073 8355712 1549358 1567856 12629508
CCND3 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 9190208 10498883 18590585 7575488 9315635 17303408 10385618 10778858 9736735 16236519 20068082 7736585 9425340 11520855 19075565 18786381 17660363 15279786
CCNA2 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 15840440 16135794 9736735 15133492 15558010 15123636 9556498 12501191 16213134 11980909 16123593
STAT1 EP300 â—¼   PHYSICAL_INTERACTION 22.0 1.0 ACSN 10918613 11134049 11830590 12193701 12223527 12796776 12811837 12967644 14607900 14764699 15265520 15814715 17016554 17513775 17559085 17689680 18272812 19833085 21263073 21930765 25960930 8683106
STAT1 EP300 â—¼   PROTEIN_INTERACTION 22.0 1.0 ACSN 10918613 11134049 11830590 12193701 12223527 12796776 12811837 12967644 14607900 14764699 15265520 15814715 17016554 17513775 17559085 17689680 18272812 19833085 21263073 21930765 25960930 8683106
AKT1 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 17623675 18182168 16926151 20333651 19158375 17964260 17570479 11116148 25904863 21901101 23275565 16024795
KAT2B EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8684459 14500836 9267036 17496784 20870727
IRF3 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 9463386 9488451 11940575 9660935 21903422 10024886 11314014
CARM1 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 15731352 21988832 11997499 11701890 15616592 16923966 18280497
EID1 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 11073989 11073990
EP300 MYOD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10944526 9001254
EP300 SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 31.0 1.0 Omnipath 21988832 23331499 9169454 12237408 10199400 11264182 7878020 8047140 12958365 19171760 11371641 16027720 17074756 17469772 21269274 15623506
EP300 TDG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11864601
EP300 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 18782771 15509516 8756628 10205054 7530500 15653507 15735682 19506034 16285960 16713569 11322950 7499365 15649887 9590694
EP300 SMAD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12419246 14500836 10673036 22298955
EP300 NCOA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15731352 20448036 10490106 9920895
EP300 MYB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 19608861 29954426 18585056 15691758 10656693 25740244
EP300 HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 75.0 1.0 Omnipath 24821806 12573436 17145710 16847340 12588875 19589782 11940656 25192544 11959990 18519678 23448368 22219185 11823643 12042299 15342390 23746844 19071119 19680224 27808477 15154850 19696166 8917528 17906695 18268343 22735262 21148070 15261140 19940151 23880760 22807441 35430356 14691445 12914934 20000859 12778114 26751287 16081065 22789427 16543236 24421387 17382325 17502379 22684029 21187066 19074848 23618863 23966271 20603618
EP300 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 9843571 11134049 12743039 15133024 15824515 15623506 16876108 21567395 16109717 17074756 20564330 10497242 15588252 17469184 15345715 11058129 10575014 16862174
EP300 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 17145710 22290435 19623618 11804596 23343194 22761862 16039586 12776737 17157259 17143292 12660246 15576399 21151179 15522869 17306568 19407812 17666529 21285352 19619488
EP300 STAT6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11509556 15145939 10454341
HIF1A FOXM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22831955 19097132
MYC FOXM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 20658516 18798339 12695333 17341548
FOXM1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 17141659 10567581 17655499 16965535 11391529
AKT1 FOXO1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 15987244 10358075 10102273 12857750
FOXO3 FOXO1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 19244250 16100571 18202312 23509296 19690465
AKT1 FOXO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 90.0 1.0 Omnipath 21440011 10358014 11756412 10358076 31308176 20452955 21798082 11410590 20398329 11311120 11544290 28279977 10217147 15132996 23331499 19216069 11237865 20214616 11463845 16076959 11030146 12228231 9829964 18951090 23180781 17570479 10102273 18593906 17646672 16680151 12456685 18423396 18985696 18988627 17962350 30728292 16670091 18786403 14664696 25241761 16341064 11980723 10358075 2984676 13679577 12560069 10377430 11251083 17680028 2987962 17254970 11864996 20041807
ESR1 FOXO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 17145710 18391971 22266855 11435445 11353774
SMAD3 FOXO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18391971 15084259
HNF4A FOXO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12519792 19740748
FOXO1 PPARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 16670091 12966085 17317207
AKT1 FOXO3 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 11154281 11715018 11923280 15169778 17680028 20214616 20398329
HIF1A FOXO3 â—¼   ENZYMATIC_REACTION ✅ 66.0 1.0 ACSN 10102273 10428030 10428780 10435632 10804084 10823814 11557773 11559532 11744734 11756417 11884613 12402042 12676992 12743597 14672622 14684737 14699081 14762718 15024076 15059920 15199147 15240700 15312748 15369676 15379897 15545625 16110315 16126909 16127144 16517405 16517406 16585195 16782875 16888645 17143338 17418790 17533374 17785433 18054315 18056423 18158893 18718909 19211554 20028863 20427344 20535745 20855962 21051947 21765015 22006996 22841746 22850421 22988108 24006507 25043024 25103413 25732824 7493931 7500013 7508926 8089148 8702901 8955077 9486205 9525945 9707622
FOXO3 AKT1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 15987244 10358075 10102273 12857750
FOXO3 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 24062311 16807346 16809346 17575143
FOXO3 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 19424579 23517348 21752881 22539004 11278373
AKT1 FOXO3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 64.0 1.0 Omnipath 19951971 11756412 11953455 11923280 20452955 21798082 20398329 21329882 10217147 11154281 11994454 23331499 10995739 19216069 20214616 11463845 21775285 20068231 9829964 17570479 10102273 18593906 17646672 16680151 18988627 21621563 15169778 17522590 25241761 23109003 11715018 19188143 15023346 17680028 26192618 11864996
FOXO3 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11435445 15367686 16807346 18312651
AKT1 FOXO4 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 15987244 10358075 10102273 12857750
AKT1 FOXO4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 58.0 1.0 Omnipath 11756412 20452955 21798082 20398329 15538382 10217147 23331499 19216069 20214616 11463845 23180781 9829964 11313479 10102273 10518537 14690436 16680151 17646672 18988627 17522590 11896584 16272144 11689711 17680028 21620960 19664994 11864996
SUMO1 HIPK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 21145359 15896780 10535925 14609633
HIPK2 PAX6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16407227
HIPK2 CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 20573984 19690332
HIPK2 CTBP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 28532298 14567915 23331499 27689990 19788416 22649776 15708980 22889244 23291169
HIPK2 PML â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 17081983 27689990 27308327 26539288 19015637
HIPK2 DAXX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23331499 19465479 14678985
KAT2B MYOD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 17145710 9659901 10944526 10619020
KAT2B SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 34576109 17074756 11058129
KAT2B SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11058129 15994459
XRCC6 MDC1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
JUN MYC â—¼   ENZYMATIC_REACTION ✅ 40.0 1.0 ACSN 11274345 11929833 11955436 11967263 12051714 15001769 15576399 15768032 15806138 16007074 16039586 16169192 16510874 17050667 17143292 17291450 17439715 17936032 18347071 18627596 19619488 19623618 20006983 20122174 20530697 20705860 20920541 21285352 21767405 22290435 22705350 22761862 23306204 23343194 24023259 25730849 26587781 7542250 8545107 8666229
STAT3 MYC â—¼   ENZYMATIC_REACTION ✅ 33.0 1.0 ACSN 10347215 11875494 12193690 12223527 12907458 14607900 14670306 15218058 15356132 15465827 15573129 16418395 17404308 18776941 19380816 20093776 20237412 20406969 20435894 20580461 20581311 21372296 21765015 21840487 22461508 23124025 23390297 23454751 23953057 24857661 27216177 28186502 7543512
KLF8 MYC â—¼   ENZYMATIC_REACTION ✅ 23.0 1.0 ACSN 11955436 11967263 12051714 15001769 15576399 16039586 17143292 17306568 17666529 17671186 17936032 19619488 19623618 20705860 21151179 21285352 22290435 22761862 23343194 24023259 25730849 7542250 8666229
MYC PPARG â—¼   ENZYMATIC_REACTION ✅ 22.0 1.0 ACSN 10432118 11274345 11283614 11875494 16327802 17558397 17873522 20027199 20237412 20551172 20581311 20713526 21093321 21372296 21406394 21765015 2191300 22067385 22461508 23124025 23390297 25002027
MYC HIF1A â—¼   ENZYMATIC_REACTION ✅ 22.0 1.0 ACSN 10432118 11274345 11283614 11875494 16327802 17558397 17873522 20027199 20237412 20551172 20581311 20713526 21093321 21372296 21406394 21765015 2191300 22067385 22461508 23124025 23390297 25002027
MYC STAT6 â—¼   ENZYMATIC_REACTION ✅ 22.0 1.0 ACSN 10432118 11274345 11283614 11875494 16327802 17558397 17873522 20027199 20237412 20551172 20581311 20713526 21093321 21372296 21406394 21765015 2191300 22067385 22461508 23124025 23390297 25002027
GATA1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 24336126 19522008 12832487
JUN MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 21835891 8276360 1774959 2498162 21607323 20410304 14523011 18037408
MYB MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 18408764 19609274 8382794 1679531 1588953 1594249 9596659 11259163 8474446 2233716 16088151
STAT3 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 19289167 17204573 18184402 22317895 20067773 15184887 15469392 10464281 9325164 20654581 21573184 17959148 22349830 9874564 20581311 19259613
FOS MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 11939505 2463066 1696944 8276360 9950153 2139817 2498162 21607323 20410304 8490168 7654239
HIF1A MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 20404562 23059786 19845622 18616527 15780936 21303984
HNF4A MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12591729 23714368 19966299 15024077
PPARG MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 11973610 17462534 16405739 19075513
SMAD3 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 15930298 20516082 14993291 17132729 16205635 25238097 11689553 17114344
ESR1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 22396492 21835891 15073177 18193094 11517191 21505052 22892083 8707895 19569049 14722073 18414489
MYC CCNA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 8386381 10713672 12835716 7608142 12937171 14519204 14729654
MYC ETS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18586674 12695333
MYC ATF4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12695333 23612979
MYC MYOD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 1850105 7970710 19723804 12101422
MYC PTMA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 8196628 15840017 8378090 1378271 8524267 12695333 9185588 10380878 9365169 17372028
JUN MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 29.0 1.0 Omnipath 15806138 16510874 22290435 18627596 19623618 11929833 23343194 15768032 22761862 17050667 16039586 20122174 17291450 20920541 17143292 20006983 17439715 15576399 21767405 23306204 8545107 22705350 18347071 16007074 16169192 21285352 20530697 19619488 11274345
HNF1A MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 17306568 17666529 23343194 21285352 15576399 21151179 22761862 22290435 16039586 19619488 19623618 17143292
MYC SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23331499 11804592
MYC SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23331499 11804592
SUMO1 PML â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 22875967 9756909 25497731 17036045 21057547 18931695 19217413 8806687 16189514 17081985 11080164 11948183 9885291 19380586 17344210
PML SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23331499 21071413 15356634 16189514 18988627
SMAD3 SNAI1 â—¼   PHYSICAL_INTERACTION 20.0 1.0 ACSN 11074002 11279127 11792802 12702545 12809600 15265520 16179589 16713975 17018611 17563753 18768831 19597490 21041997 21042762 21577210 21614932 22331441 22514743 8515656 9389648
SMAD3 SNAI1 â—¼   SHARES_COMPLEX 20.0 1.0 ACSN 11074002 11279127 11792802 12702545 12809600 15265520 16179589 16713975 17018611 17563753 18768831 19597490 21041997 21042762 21577210 21614932 22331441 22514743 8515656 9389648
KLF8 SNAI1 â—¼   DOWN_REGULATES ✅ - 8.0 1.0 ACSN 16617148 16831886 17563753 17671186 18832382 20731704 21317430 22406545
SNAI1 ETS1 â—¼   UP_REGULATES ✅ + 66.0 1.0 ACSN 10048576 11283614 11708773 12490555 12545156 12668723 14623871 14673164 15111329 15151915 15155580 15181457 15448698 15459715 16001073 16079281 16232121 16510505 16556862 16617148 16716598 16831886 17018611 17055429 17093497 17403902 17490644 17537911 17550342 17563753 17615296 17671186 18172008 18297062 18832382 19208835 19412634 19564415 19597490 19935649 20027199 20702634 20706219 20713526 20731704 21041997 21051859 21159887 21199805 21317430 21577210 21685935 21883379 2191300 22006115 22286765 22406545 22439866 22514743 22796940 22945800 23140366 23869868 8844971 9157999 9618481
SMAD3 SNAI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 20731704 9389648 18832382 16831886 17563753 22406545 11074002 21317430 16617148 17671186
STAT1 STAT3 â—¼   DOWN_REGULATES ✅ - 46.0 1.0 ACSN 10485906 10754326 10820262 10952726 11134049 11399519 11830590 11875494 11964313 12193701 12223527 12433365 12796776 12811837 12907458 12967644 14607900 14607933 14660645 14764699 15465827 15644117 15699106 15814715 16127449 16878026 17016554 17260466 17404308 17485448 17513775 17559085 17689680 18272812 18345002 19833085 19879327 21097505 21263073 21930765 23390297 25960930 6357187 7594497 8683106 8871614
STAT3 HIF1A â—¼   DOWN_REGULATES ✅ - 24.0 1.0 ACSN 10347215 10973499 12223527 14607900 14670306 15218058 15356132 15573129 16418395 18776941 18985005 19380816 20093776 20237412 20406969 20581311 21840487 23124025 23454751 23953057 24857661 27216177 28186502 7543512
STAT3 FOS â—¼   UP_REGULATES ✅ + 38.0 1.0 ACSN 10347215 11528470 12223527 13130303 14607900 14670306 15218058 15356132 15573129 15810077 16418395 16716598 16831886 17403902 18297062 18776941 18832382 19380816 19412634 20093776 20237412 20406969 20581311 21317430 21840487 21883379 22006115 22943793 22945800 23124025 23454751 23953057 24857661 27216177 28186502 7543512 7768934 9278421
STAT1 STAT3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19122651 17558387 22693070
STAT3 CCND3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16084951 18310224 15184887
STAT3 FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 17204573 14737107 12640143 12600988 11685114 8071311 15040450 16293640
STAT3 HIF1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 19265129 18644974 16007214 20924113 17597020 23991099
NCOA1 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11773079 16713569 15313931
SRC STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 88.0 1.0 Omnipath 19901323 10918587 9305919 8272872 29036202 9344858 12626508 10815799 16497976 15592455 16713569 17389395 12576423 11350938 9484840 11294897 28978186 18070987 12244095 27472461 21690253 23928694 22303479 8657134 11404481 9083098 14963038 8626374 17016520 9566874 10982829 15212693 11940572 11429593 14551213 15037656 15313931 11850821 9154828 9582023
PIAS3 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 29.0 1.0 Omnipath 11709556 21988832 23331499 12804609 9388184 18037959 15138572 11429412 11266437 20516148 9724754 16189514 19569236
STAT3 STAT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 25609649 8662591 12070153 31462771 25241761 11722592 8710878 9794795 23268184 15284024 16189514 9535918 11594781
STAT3 HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 15735682 18985005 10973499
SUMO1 TDG â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 16763556 15959518 17060459 21284855 20504299 16189514 16524884 11889051 10961991
SMAD2 IRF3 â—¼   DOWN_REGULATES ✅ - 24.0 1.0 ACSN 10925299 11074002 11279127 11399519 11792802 11875494 12193690 12702545 12809600 15265520 15644117 16127449 16179589 16713975 17260466 17689680 21042762 21614932 22331441 23390297 6357187 8871614 9389648 9670020
SMAD3 IRF3 â—¼   DOWN_REGULATES ✅ - 25.0 1.0 ACSN 10925299 11074002 11279127 11399519 11792802 11875494 12193690 12702545 12809600 15265520 15644117 16127449 16179589 16713975 17260466 17689680 18768831 21042762 21614932 22331441 23390297 6357187 8515656 8871614 9389648
ATF4 CREB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 17669268 17434604 18441292 15240803 15888447 16121183
JUN MYOD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 2167198 19723510 1313772 8120060 8264634 1310896
SRF MYOD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17377068 8744946 9658178 23406902
STAT1 STAT2 â—¼   PHYSICAL_INTERACTION 20.0 1.0 ACSN 11134049 11830590 12193701 12223527 12796776 12811837 12967644 14607900 14764699 15814715 17016554 17513775 17559085 17689680 18272812 19833085 21263073 21930765 25960930 8683106
STAT1 STAT2 â—¼   SHARES_COMPLEX 20.0 1.0 ACSN 11134049 11830590 12193701 12223527 12796776 12811837 12967644 14607900 14764699 15814715 17016554 17513775 17559085 17689680 18272812 19833085 21263073 21930765 25960930 8683106
STAT1 FOS â—¼   UP_REGULATES ✅ + 20.0 1.0 ACSN 11134049 11830590 12193701 12223527 12796776 12811837 12967644 14607900 14764699 15814715 17016554 17513775 17559085 17689680 18272812 19833085 21263073 21930765 25960930 8683106
STAT1 FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 8874187 7510676 8830676 12600988 7507205 8770944 17558387
FGFR1 STAT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 17496910 11447289 19615955 16488589 6321473 11997436 12040186 19568798 15567848 15173823 14585353 15199124
STAT2 STAT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 10490982 8621447 24065129 17923090 15978943 1502203 10446176 9724754 14722125 21178011 15825084 21268015 12048190 8605877
ETS1 STAT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15996661 19935876
SRC STAT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 11839738 10918587 9344858 7543024 15322115 10358079 14978237 11294897 7690989 16189514 12637327 11438544 10748192 7657660 12817007 9355737 11152457 10982844 7592750
SMAD3 SMAD2 â—¼   PHYSICAL_INTERACTION 41.0 1.0 ACSN 10454538 10964912 11007770 11013220 11074002 11279127 11283613 11283614 11792802 12545156 12702545 12809600 15001984 15095404 15155580 15265520 16179589 16713975 17055429 17550342 17705132 18353785 18768831 19815509 19901969 20027199 20713526 21042762 21252118 21614932 2191300 22331441 23140366 23338822 23869868 8515656 9312026 9389648 9618481 9670020 9865696
SMAD3 SMAD2 â—¼   PROTEIN_INTERACTION 41.0 1.0 ACSN 10454538 10964912 11007770 11013220 11074002 11279127 11283613 11283614 11792802 12545156 12702545 12809600 15001984 15095404 15155580 15265520 16179589 16713975 17055429 17550342 17705132 18353785 18768831 19815509 19901969 20027199 20713526 21042762 21252118 21614932 2191300 22331441 23140366 23338822 23869868 8515656 9312026 9389648 9618481 9670020 9865696
SMAD2 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 21988832 26186194 12543979 9111321 15084259 9311995 25878769 18729074 12700238
SMAD3 CTGF â—¼   ENZYMATIC_REACTION ✅ 20.0 1.0 ACSN 11013125 11074002 11279127 11376132 11792802 12702545 12809600 15265520 16179589 16713975 18768831 21042762 21098712 21614932 22331441 22652804 23784029 25374926 8515656 9389648
SMAD3 ETS1 â—¼   ENZYMATIC_REACTION ✅ 20.0 1.0 ACSN 11013125 11074002 11279127 11376132 11792802 12702545 12809600 15265520 16179589 16713975 18768831 21042762 21098712 21614932 22331441 22652804 23784029 25374926 8515656 9389648
SMAD3 PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21836474 21926264 12457461 12524424
AKT1 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 23331499 25241761 15104092 16362038 21071413 18988627 26297431 15048128
PIAS3 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23331499 16189514 14691252
SMAD3 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 23331499 9732876 10220381 11306568 21829441 10903323
SMAD3 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11555647 23331499
JUN FOS â—¼   PHYSICAL_INTERACTION 21.0 1.0 ACSN 10606235 11274345 11274400 14673140 15067049 16393692 16394015 17439715 18222063 18754863 19667062 19846528 21385848 21790308 22381618 22634314 22723415 23430059 26587781 8545107 9064320
JUN FOS â—¼   PROTEIN_INTERACTION 21.0 1.0 ACSN 10606235 11274345 11274400 14673140 15067049 16393692 16394015 17439715 18222063 18754863 19667062 19846528 21385848 21790308 22381618 22634314 22723415 23430059 26587781 8545107 9064320
CREB1 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 10471787 8647095 10403485 2140898
ESR1 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11477071 17963131 10037443 16679312
JUN FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 2513130 14561487 8617996 8934539 19255142 9217081 12760745 2498806 10521486 8597411 10858536 12392213 9819441 1380150 23562910 1944274 9867253 9571041 1900040 2511006 14684847 15467742 12231642 11950097
JUN CCNA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 9486962 23385061 15574764 17182846 15737994 21069729 9511728 20531301 21029732
JUN MYB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 1527086 8670250 12475180
JUN SRC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 7499226 16798740 23533633 14736735 18216279
ESR1 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11477071 17317669 16713569
FOS JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 73.0 1.0 Omnipath 20498278 16714286 21675959 25609649 23602568 9872330 20102225 8380166 18848838 18535250 2516828 8397339 15867431 18172215 9346889 10779323 9732876 16928824 26496610 15994313 22719067 24029232 16511568 20195357 11053448 20936779 26186194 18619508 20511396 16008525 10488148 21199371 8617242 17440114 16055710 15319445 11090181 9160889 23661758 1631061 15718494 11431474 31515488 8440710 7816143 20410304 34671206
JUN ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11477071 17317669 16713569
JUN CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 2138276 1827203 18641343 8290251
JUN ETS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8557686 20195357
JUN CCND3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 18813803 19219074 16406505 16880536 16054035 19190345 17000779 17439715 8545107 16396903 11274345 20107231
KLF8 KLF4 â—¼   PHYSICAL_INTERACTION 8.0 1.0 ACSN 17671186 19216735 19506021 19751731 19901072 20964627 21416054 21681822
KLF8 KLF4 â—¼   DOWN_REGULATES ✅ - 8.0 1.0 ACSN 17671186 19216735 19506021 19751731 19901072 20964627 21416054 21681822
PPARG STAT6 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 10432118 10485906 12223527 12244147 14610620 15634881 17681149 21093321 23124025 24204259
PPARG STAT6 â—¼   PROTEIN_INTERACTION 10.0 1.0 ACSN 10432118 10485906 12223527 12244147 14610620 15634881 17681149 21093321 23124025 24204259
KLF4 PPARG â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 10432118 10925299 12193690 21093321 21670502 23390297 6357187
PPARG STAT6 â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 ACSN 10432118 10485906 12223527 12244147 14610620 15634881 17681149 21093321 23124025 24204259
GATA3 PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 18522800 15632071 15896659
SRC PPARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23331499 30323259 10322133 26385316
CARM1 PPARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18188184
NCOA2 PPARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 23331499 11500849 9238002 17513608 21071413 15026545 18988627 18584035 10944516
HIF1A AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 19144925 17220299 17488804 14726529 15277220
HIF1A ETS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 17615296 9157999 9278421 11708773 16716598 12080085 10403805 16887934 15181457 7539918 12490555 1823643 12829734 13130303 15451019 9746763 8943284 15111329 9159130 11566883 21041997
SRC HNF4A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 16713569 22308320
SRC ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 32.0 1.0 Omnipath 15784253 25364741 17400812 16957778 17627277 15140878 11032808 23065768 12736255 7539106 17921256 27472465 14963108 24487689 25275301 12630920 22865929 14766010 30148069 11013076 15020686 9500442 17284441
SRC AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 11445557 25241761 23242524 18283331 12600984
ETS1 FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9349499 8262053 1722028
ESR1 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11029009 15569929 18450422 20664923 15496458
AKT1 GATA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 27053161 16107690 20101202 8206977 26680303
AKT1 CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 35.0 1.0 Omnipath 11175347 11756412 12356771 15733869 20452955 20398329 11160957 10217147 19216069 20214616 11463845 9829964 7958915 12235136 16680151 17646672 9687510 8887554 11698596 8688081 17680028 9528766 11018520 11969286 12519783 11909979 15725726
AKT1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 18521086 26944939 11108261 17627277 20101208 17570479 15604293 23169992 26554417 16452229 15193262 7838153 12374744 11139588 26272591 11432835 20179234 11507039 9528769
ESR1 FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 8114761 9528985 18414489 10037443 21813366 11726205
SRF FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 45.0 1.0 Omnipath 9315625 10742173 8864058 8986626 19581295 9690619 10777594 11846562 12242287 2104799 17938209 9111305 8007980 12760745 11862715 1902475 8423791 10642500 10330504 10961986 9032300 2511007 8164681 7854423 17182846 2200737 9271374 10369679 8413226 19173292 9349499 1630900 8262053 10319327 7910456 9545312 9571041 9734357 8764983 12231642 2493627 14693367 18557893 7588632
NCOA1 FOS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18511550 10847592 9642216
ESR1 PTMA â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 10938099 12149645 11459795
SRF CREB1 â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 15733869 28286024 15542842 9770464 1833716 18088355 7823924 7551568 15449318 2040600
CREB1 CCNA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 11160720 20857405 8641461 17325033 12869629 19343785
STAT6 KLF4 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 10485906 12223527 12244147 14610620 15634881 23124025 24204259
GATA3 CARM1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 14631847 12498683 11010967 14675539
ESR1 CARM1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 14631847 12498683 11010967 14675539
E2F3 CCNA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15510213 11980909 10733529 18319725
NCOA2 NCOA1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 11387316 12815072 10334992 16908160 11870371 10334993 16541101
NCOA1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 42.0 1.0 Omnipath 18451880 9192892 16957778 11014206 16713569 17627277 23975195 15140878 15604093 12738788 17363140 11003650 10454579 16606617 26487511 11165056 10760302 10731636 12630920 14715875 9773983 9427757 9121466 20608937 12714702 9259327 9192902 11358671 10598586 12574227 11113179 12554772 11682626 9774463
GATA3 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17616709 20130088 20068169
ESR1 NCOA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 18499756 9192892 9430642 11014206 19460354 15657427 23331499 11477071 26487511 16645043 12612084 20348541 12630920 14766010 17697320 11937504 12714702 12554772 9774463
ESR1 GATA3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 26153859 25303530 10096242
HNF4A HNF1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 8367288 9111350 9792724 8674436 11717395 9313764 9837989 9204893 9232592 1734282 20850486 8735941 11145965 11085951 10331424 8808405 12601360 16670373
SMCA4 SNF5 â—¼   PROTEIN_INTERACTION 1.0 1.0 HIPPIE 19164553 9128241 10078207 12368262 18809673 18414052 21520050 15150092 19448667 30108113 29374058 11726552 20460684 16287714 30962207 18042045 9845365 11238380 8895581 11486022 23540691 15985610 22939629 26344197 14559996 20506188 22573825 31759698 22140357 16687403 23602572 24981860 33961781 31043422 9744861 9584200