Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
ABL1 CAV1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20808760 1000457
ABL1 FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ABL1 MUC1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 5218915 16888623
APC SCRIB â—¼   COLOCALIZATION 2.0 0.8 intact 16611247 6549797
DVL1 APC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20224554 10330181
DDB1 AHR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19651607 0902132106
MUC1 EGFR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11483589 5214341
NFKB1 EP300 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12456660 16135789
EP300 MUC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1203339109 22869720
EP300 FOXO3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11896584
FOXO3 HIF1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18268343 0706790105
MCM7 FHL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5212181 10649446
HIF1A MUC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1203339109 22869720
TOP2A PIN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11940573 5215253
UBR5 SMAD2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
LATS2 YAP1 â—¼   PHOSPHORYLATION ✅ - 0.8 0.8 Signor 22658639
HNF4A AXIN2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19149881 11940574
AHR CRYAB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21494593 18805402
SRC FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219079 16966330
HDAC6 FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
AXIN1 SMAD7 â—¼   COLOCALIZATION 2.0 0.8 intact 16601693 5218493
SMAD2 RXRA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
SMAD3 HDAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10199400 11427533
SMAD3 MET â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15339794
SMAD3 AHR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11259615
PTEN CAV1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12176037 6731969
HIF1A PTEN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18340011 19648120
DNMT1 PTEN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19339266 21229291
CAV1 PTEN â—¼   COLOCALIZATION 2.0 0.8 intact 12176037 6731969
GSK3A AXIN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219669 17318175
GSK3B AXIN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219694 17318191
AMER1 AXIN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21304492 17510365
NFKB1 HDAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11931769 5215238
SRC RHOA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10592173 23027962
CAV1 LRP6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16890161
SRC ERBB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6731430 11940572
PTPRF CAV1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12176037 6731969
GSK3B APC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 10698523
HNF4A ERBB2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17914096 10915780
HNF4A PITX2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 1312668 9651383
TCF7 LEF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 32448362 25921273
PITX2 LEF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15728254
LEF1 PITX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15728254
PTPRJ MET â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 intact 6671721 12475979
DDB1 HDAC1 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 34026424 25189618 24249678 26679995
NFKB1 EP300 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 11739381 23811396 14662860 12471036 20065107 22013068 12960163
EP300 HDAC1 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 14968110 30110629 22778253 16787918 33742100 18722353 22731250
CAV1 RHOA â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 31871319 20460433 9647788
CBP SRC â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 16860316 15615775 16713569 22364282
CADH1 FGFR1 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 11401320 25241761 27371729
SMCA4 CBP â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 19448667 9584200 9443979
LRP6 AXIN1 â—¼   RELOCALIZATION ✅ - 0.81 0.81 Signor 18632848
CTNA3 APC â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
DVL1 APC â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 20224554 11425858
APC PAXI â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 20224554
DDB1 AHR â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19651607 17392787
DDB1 CTNB1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 27684187 19651607
EGFR PSMD4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 20029029 31980649
EGFR CADH5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24658140 25402006
EGFR IGF1R â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17047074 17307140
EGFR FHL2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 29321665 15657067
HDAC6 EP300 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19344692 15102857 12718889 22778253 23133622
EPHA2 CTNB1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 18948590
CBP FOXM1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28387346 27542221 15024056
FOXO3 IKKB â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 15084260 25241761
FOXO3 CTNB1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 15905404 29361949
CTNB1 LZTS2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 27684187
LZTS2 P85A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33420362 29395067
MCM7 CTNB1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 27684187 23764002
CTNA3 PKP4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CADH8 PKP4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
PKP4 CADH1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 25468996 12615965
CTNB1 PSMD1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 27684187
SOX2 UBR5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30894683 23667531
FBW1B YAP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21900206 22017875
YAP1 CTNA1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21376238 31501420
YAP1 CADH1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21376238 25468996
YAP1 IQGA1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21376238 27684187
YAP1 GSK3B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24976009 29789528
AXIN1 AXIN2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22682247 20128690
CDC73 BCL9 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 16630820 17113272
LAP2 SMAD7 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 12650946
SMAD7 LEF1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 15750622 15684397
CTNB1 PTEN â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 20372837 20123964
AXIN1 USP9X â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22682247 17510365
PTPRF RHOA â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31871319 25458010
RHOA CTNB1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31871319 31980649
RHOA PLAK â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31871319 31980649
KC1A LRP6 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
LRP6 CTNB1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31262711 16890161
CTNB1 CAV1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19244345 18356165
FGFR1 HS90B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22939624 31980649
RASK IGF1R â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 27684187
IGF1R CTNB1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 27684187 22261717
IGF1R ERBB2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17307140 30898150
NFKB1 RUVB1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 14743216 25609649
CTNB1 PTPRC â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 12370829 19167335
CTNB1 PSMD4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 27684187
HS90A GSK3A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22939624 30824926
GSK3A HS90B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22939624 30824926
CYBP ERBB2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 25036637 31980649
MAGI1 PARD3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 34079125
PARD3 CTNA1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 17057644
ANK2 CTNB1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 31264976
HS90B ANDR â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 32206096 21730179
RASK 1433Z â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 27684187
1433Z SI1L1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
1433Z PKHA7 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CADH1 ASPP2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 25468996 25344754
CTNA3 CADH1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CADH1 KC1A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 27684187 25468996
CADH5 PTPRU â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CADH5 CTNA2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CADH5 ARVC â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CADH8 CTND1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CTNA3 CTND1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CTNA3 ARVC â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CADH8 ARVC â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CNBP1 CTNA1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
PKHA7 CTNA1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 28877994
CTNA1 CTNA2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 33961781
CADH8 CTNA1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
SLAF7 CTNB1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
MAGI2 CTNB1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 11826105 11526121
CTNB1 ZO1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 27684187
PKHA7 CTNB1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 28877994
SOX2 CTNB1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 23539445 23667531
CTNB1 HINT1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22647378 16014379
CTNB1 SI1L1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 27684187
CTNB1 SI1L3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 27684187
CTNB1 PKHA6 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 27684187
CADH8 PLAK â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
PLAK CTNA2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 7650039 26344197
CADH8 CTNA2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CADH8 PSN1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CTNA3 CNBP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CTNA3 CAD10 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CTNA3 CADH2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CTNA3 CADH3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
MLP3B HS90B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 20562859 33545068
USP9X YAP1 â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
FBW1B APC â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 25900982 25515538 28514442 33961781
APC AMER1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 24251807 17510365 26496610
RASK EGFR â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 34079125 30194290 30639242 12783862
EGFR EPHA2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 24797263 15657067
CTNB1 EP300 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 15572674 33742100 15806138 26123998 33190089 11050151 32603375 30986748 15060161 30836930 26657156 12408825
HDAC6 MCM7 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194 23703321
TRRAP RUVB2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 28561026 33961781 26496610
USP9X YAP1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22939629 26598551 29449692
PAXI FYN â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 16713569 10804218
SMAD3 FBW1A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 11359933 14988407
AXIN1 DVL3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22682247 12805222 20128690
SMCA4 HDAC1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 19081374 20596014 12192000
HDAC1 CTNB1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 16204248 19166851 31130994 10958684 27684187 17412698
TBL1X CYBP â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 25241761 11389839
HIF1A RUVB2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 27320910 20603076
FGFR1 CBP â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22539306 25241761 19261810 15929978
1433Z IGF1R â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 27684187 9581554
SOX2 USP9X â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 23667531 31605775
HDAC6 HS90A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 15937340 23703321 15916966 18591380 22367781 19158084 17851643
AHR CTNB1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 23174221 31675361 19651607
FBW1A LAP2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 25900982 26056141
CTNB1 1433Z â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 17287208 27684187 15492215 22912335
IKKB FBW1A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 11158290 20797629 19656241
FBW1A DLG5 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 25900982 31787846
LEG9 PTPRJ â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
PKHA7 CTND1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28877994 19041755
CTND1 CADH3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 23180380 8660921
CTNB1 MET â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 11254878 11929826
LEG9 MET â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
HD CTNB1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 32814053 20531388 17500595
RASK PLAK â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 34079125 27684187 30194290
CTNB1 RASK â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 34079125 27684187 30194290
CTNB1 ARVC â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 34079125 27684187 33961781
CTNA1 PSN1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 10635315 16189514
CTNB1 HS90B â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 31536960 27684187 15492215
CTNB1 BCL9L â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 24360964 15574752
CTNB1 HS90A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 31536960 27684187 32814053
CTNB1 VINC â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22720799 9405455 27684187
CTNA3 PLAK â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 23718855 32296183 23136403
AXIN1 DVL3 â—¼   PHYSICAL_INTERACTION 834.0 0.83 STRING 36370105
HDAC1 SMAD2 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
ABL1 EGFR â—¼   PHYSICAL_INTERACTION 839.0 0.84 STRING 36370105
ACTN4 CTNB1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 16204054 25241761
EGFR EMD â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 24797263 20937808 28065597
EGFR PTPRC â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 31980649 19167335
FOXO3 EP300 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 19592618 25609649 11896584
ERBB2 EPHA2 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 30898150 28628118 28205554
CTNB1 PKP4 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 34079125 12047349 33961781 27684187
CTNB1 UBR5 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 32914356 28689657 21118991
PECA1 FYN â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 16713569 10858437
DVL1 SMAD7 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 12650946
SMAD2 CTNB1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 12000714 23246962 20571128 27684187
DVL1 SMAD3 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 12650946
SMAD3 CTNB1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 12000714 22241478 20571128 21965288 27684187
PAXI PTEN â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 11857088 23397142
DVL1 CTNB1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 25241761 10806215
SRC IKKA â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 12707358 15749833
SRC CTND1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 12640114 11382764
CTNB1 SCRIB â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 34079125 24550280
FGFR1 CTNB1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 18302981 11401320 25241761
NFKB1 HS90B â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 14743216 25241761 25609649
LATS2 CTNB1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 24360964 24255178
GSK3B HS90A â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 22824801 19682504 23455922 30824926
HDAC6 CTNB1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 18356165 23084749
GSK3A CTNB1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 27684187 25897075 17510365 26496610
FBW1B AMER1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 28514442 17510365
CTNB1 AMER1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 17510365 26496610
CHD8 ANDR â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 33640491 20308527
CTNB1 LAP2 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 34079125 12047349 27684187 15123239
CBP IKKB â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 14597638 25241761 11971985
ARVC CADH1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 11058098 25468996
CTNB1 PAXI â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 27684187 22728435
IKKB HS90B â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 14743216 25241761
ZO1 CTNA1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 34079125 9214391
DVL3 CTNB1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 10644691 10806215
PTPRU CTNB1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 16574648 12501215 9054423
MLP3B CTNB1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 23736261 30806153
CTNA2 CNBP1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 28514442 16325583 33961781
AXIN2 APC â—¼   PHYSICAL_INTERACTION ✅ + 0.84 0.84 Signor 10911903
AXIN1 APC â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 7025676 19131971
EGFR IQGA1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 19114553 21349850
ANDR EP300 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 18487222 16713569 27903893 24480624 10779504 32668201 28549433 23172223 34585037 23518348
ITF2 EP300 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 17410209 17050667
PLAK MUC1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 9139698 12939402
ERBB2 MUC1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 11278868 12939402
CTNB1 TRRAP â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 18347063 16510875 16510874
CRYAB CTNB1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 32814053 31638302 22158051 17487982
FYN HS90B â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 22939624 32707033 31980649 28514442
CTNB1 SMAD7 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 18593713 15684397
SMAD2 HDAC1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 10199400 11226163 31130994 14699069
RHG21 RHOA â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 31871319 15793564 32203420
HS90B SRC â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 32707033 28215707 31980649
LATS2 USP9X â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 32707033 29183995 28720576 24255178
1433Z GSK3B â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 15073173 12551948 17317006
CTNB1 RXRA â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 12771132 27684187 25241761
MET P85A â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 24728074 7513258
1433Z HS90A â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 31536960 15161933 31273033
HS90A CYBP â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 27249023 19875381
CTNB1 CYBP â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 20181957 25241761 21466614 11389839
CAH9 CTNB1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 17220880 14567991
HDAC1 SOX2 â—¼   PHYSICAL_INTERACTION 856.0 0.85 STRING 36370105
ABL1 ERBB2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 22973453 16273093 19275932
ACTN4 IQGA1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 22662192 26496610
LZTS2 APC â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 28514442 29395067
CTNB1 DOT1L â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 21103407 20203130
EGFR ANDR â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 12534934 15288768 15305378
EP300 SMAD3 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 9679056 15824515 15688032 16109717 15345715 20564330 9843571 15133024 10497242 17469184 15623506 10575014 15588252 18055455 16876108 21567395 11134049 12743039 11058129
MCM7 HS90B â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 22863883 23764002
PIN1 TOP2A â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 11940573 16713569
YAP1 AXIN1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 24976009 29789528
PIN1 KPYM â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 21900206 23178880 16055720
PIN1 CTNB1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 11533658 16713569
HS90A FYN â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 28514442 16888650 31980649 22939624 32814053 33961781 32707033
FYN PTPRF â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 12496362 31413325
FYN CTND1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 12640114 12835311
SMAD7 AXIN1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 16601693 18593713
AXIN1 PLAK â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 26496610 26871637
SRC IKKB â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 12707358 15749833 12645577 15456896
SRC RXRA â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 17363140 15116119 10517671 15140878
HDAC6 ERBB2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 20029029 31980649
CTNB1 DNMT1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 33643786 25753001
MAGI1 CADH1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 25468996 10772923
CTNA1 CTND1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 34079125 7651399
IKKA HS90B â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 14743216 33961781
ASPP2 CTNB1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 34079125 25344754
HS90A KC1A â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 29593330 22824801 22939624 32707033 23455922 19875381
RHG21 CTNA1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 34079125 32203420
CAD11 CTNB1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 25466890 18302981 10029089
LEG9 CTNB1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 31995728 17353931
PITX2 CTNB1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 19174163 25241761 15728254 12464179
CTNB1 CAD10 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 26496610 10861224
LEG9 PLAK â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 31995728 17353931
ABL1 CTNB1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 23950177 17318191
HD DDB1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 25959826 17500595
EGFR PTPRF â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 24797263 31980649 24189400
SRC EP300 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 26695438 10973497
LZTS2 SI1L1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 29395067 33961781 26186194
LZTS2 SI1L3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 29395067 33961781
SCRIB PKP4 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 30126976 24550280
GSK3A AXIN2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 33961781 30824926 23602568
AXIN2 CTNB1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 27684187 22056988 17510365 10966653
CBY1 1433Z â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 19940019 33961781 28514442 18573912
CBP SMAD2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 9679056 16751102 27566588 18003620 17283070 33323411 20403362 15231748 15750622
AXIN1 FBW1B â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 25900982 22682247 25332235
AXIN1 GSK3A â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 17318175 23959799 26912724 26496610 19131971 33961781 23602568 27684187 17510365
RASK RHOA â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 30194290 31871319 27229929
LRP6 GSK3A â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 16365045 30824926
CTNB1 HIF1A â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 22865883 23246962 24650032 17220880 23671189
HIF1A ANDR â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 22865883 17426252
FGFR1 P85A â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 25241761 18412956 8321198 15117958
FGFR1 KPYM â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 25263439 32572027 24606918
P85A IGF1R â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 8603569 25241761 7642582 8697095 7589433
CTNB1 NFKB1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 15829968 25241761 19358846
NFKB1 FBW1B â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 22017875 25515538 25332235 33961781 12482991
GSK3B HS90B â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 30711629 23455922 30824926
1433Z VINC â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 22863883 15161933
CTNB1 CTND1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 9535896 33961781 34079125 11712088 27684187
ITF2 PLAK â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 16306047 14661054 14517306
PECA1 CTNB1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 25241761 10801826
CTNB1 AF10 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 21103407 20203130
PSN1 PLAK â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 16306047 11226248 19114997
EGFR MUC1 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
EP300 NFKB1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
AMER1 AXIN1 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
ABL1 1433Z â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 15696159 16888623 25852190
ACTN4 MAGI1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16713569 12042308
ACTN4 ZO1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16944923
EGFR CTNA1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 24189400 25241761 15657067
CTNB1 EMD â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 27684187 16858403
AHR EP300 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 10999956 17392787 21988832
EP300 SMAD2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 11371641 21988832 10199400 12237408 11264182 15623506
EP300 CBP â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 9267036 25314079 10899165 31753913 30110629 15598887 17970752
CTNB1 FOXM1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 22014570 26912724
GSK3B MUC1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 9819408 11152665
PKP4 CADH5 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 12426320 33961781 28514442
CTNB1 TOP2A â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 27684187 16230076 17983804
LATS2 YAP1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 18640976 21041410 25670202 34404733 30865227 33368671 18413746 18565851 26578655 28205554 28754671 25751139 19797269 30472188 29183995 28628118 21832154 25796446 22863277 26598551 21041411 30266805 19919647
YAP1 CTNB1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 24976009 21376238 23245941 27173435 33643786 29789528 27684187
AXIN2 GSK3B â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 12183362 10966653 33961781 23602568 32707033 23455922 29568061 30824926
PIN1 SMAD2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 19920136 19122240
FYN CTNB1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 12640114 25241761
SMAD2 LEF1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 10890911 15750622
GSK3B SMAD3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 21310903 18172167
SMAD3 LEF1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 10890911 15750622
MAGI2 PTEN â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 10760291 11707428
FBW1A AXIN1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 22682247 10228155 24976009 29045831 25900982 29789528
AXIN1 AMER1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 22682247 17510365 26496610
TBL1X CTNB1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 20181957 25241761 18193033 11389839 33054136
CAV1 PTPRF â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 34079125 12176037
NFKB1 RUVB2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 14743216 15829968 25609649
ANDR GSK3B â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 15361837 15178691
GSK3B PSN1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 17360711 11193155 10997338 16814287 11104755
PARD3 CTNB1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 34079125 17057644 25241761 27684187
CTNB1 HNF4A â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 12944908 25241761
ANDR ITF2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 12799378 16713569
1433Z SI1L3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 15161933 33961781
1433Z ASPP2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 15161933 26496610
1433Z RHG21 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 15161933 33961781
PKHA7 CADH1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 25468996 28877994 19041755
CADH1 VINC â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 9405455 25468996 9535896
PSN1 CADH1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 11226248 11953314 16126725 10635315 19114997
CADH5 CTND1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 9378757 28514442 11855855 33961781
CADH5 CTNA1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 17057644 12003790 33961781 9434630
CADH5 PLAK â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 12003790 33961781 9739078 9434630
TF7L2 PSN1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 11504726 16306047
FBW1A PLAK â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 25900982 16189514 10803460
PTPRJ CTNB1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 12370829 19167335
IKKB CTNB1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 25241761 11527961
IKKB HS90A â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 14743216 19786027 11864612
IKKA HS90A â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 14743216 11864612 22384180 33961781 19875381
IKKA CTNB1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 11527961 12589056
CTNA1 CADH3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 10381631 8227214 1924379 10910767
PKP2 CTNB1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 34079125 27684187 11790773
DLG5 CTNB1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 34079125 27684187 12657639
KPYM CTNB1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 27684187 29463646 22056988 27485204
CADH8 CTNB1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 9521872 33961781 28514442
CTNB1 CADH3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 10381631 11889072 10910767 12800191 33961781 23180380 27684187 8227214
CAV1 EGFR â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
EGFR MET â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
EGFR ACTN4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 24658140 25402006 31980649 26320552
FBW1A APC â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 10228155 29045831 25900982 33961781 10074433 19615732
APC CNBP1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 33961781 15327768
PTPRJ EGFR â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 19836242 9115287 19167335
SMAD3 FOXO3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15084259 24920680 21532621
FOXO3 CBP â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 22474372 25609649 15126506
FOXO3 1433Z â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11864996 28514442 17389761 10102273 33961781
PKP4 PSN1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 10037471 10092585
HDAC1 TOP2A â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11062478 11136718
RUVB1 TRRAP â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11839798 28514442 20371770 26496610 33961781 22939629 26344197
YAP1 FBW1A â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 21900206 28514442 20048001 24976009 32292505 33571521 29891922 32483419 29725063 33961781 29789528 30804013
CDC73 CTNB1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16630820 21726809 29774127
SRC FYN â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 31980649 19711372 9169421 33961781 16966330
P85A FYN â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 25416956 16713569 8294442 7520528 8394019
LAP2 SMAD2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 18729074 17591701 12650946 18003620
HIF1A SMAD3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 12228247 28471448 11486006 14741200
KC1A AXIN1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11884395 22682247 17510365 26496610
AXIN1 LRP6 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 22682247 19107203 23959799 24976009 28966723 16890161 20128690 23892894
HDAC1 ANDR â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15640443 11994312 16713569 15835920 26468294 34585037
CTNB1 SKP1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 12820959 20181957 9990852 18805092 11389839 25241761 27684187 21466614
GSK3B LRP6 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 19107203 16890161 16365045
CAV1 LRP6 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 34079125 28966723 16890161
HIF1A HS90B â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 20668552 19802386 18538669 26517842
HS90A SRC â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16189514 31980649 1310678 16844778 22315411 28537252 32707033
CADH1 SRC â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 31286874 18057010 10744074 25468996 21685945
SRC P85A â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 12210743 25241761 16713569 23065768 12393736 24498420 7499252 10487518 32814053 16230374 23397142 19861161 19903481
SRC PECA1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 9162084 10801826 12775720 10858437
SRC CAV1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 8910575 8632005 8621645 29720121
CAV1 ANDR â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11278309 16713569
HS90B ERBB2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 22939624 28369073 20650008 24189400
ASPP2 PARD3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 25344754 34079125 24366813 28400336 23606740
PARD3 1433Z â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 14676191 15161933 33961781
CTNB1 CHD8 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 22083958 11744694 18378692
LAP2 ARVC â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11821434 24550280 15123239
STF1 CTNB1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 12554773 12861022
FHL2 ANDR â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 10654935 16713569
ANDR SMCA4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 18487222 19762545 33640491 28611094 14966121 34585037
CBP HD â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15994095 16713569 11607033 16456924 11264541 10823891 17500595 30994454
IQGA1 CADH1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 10608854 25468996
CTND1 PTPRJ â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 12370829 12475979
PTPRJ MET â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 12370829 19167335 12475979
SMCA4 CTNB1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 19571879 11532957 29463646
CADH2 CTND1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 14625392 12604612 20371349 21357690 33961781
CTNA1 CADH2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 22939629 12604612 14625392
FBW1B CTNB1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 22682247 10321728 22017875 24500709 25515538 25332235 16085715 25900982 25609649 27684187 17510365
PTPRF CTNB1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 9245795 12095414 11245482
CTNB1 TCF7 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 25678599 27684187 19358846 16442529 17510365
CTNB1 RHG21 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 34079125 32203420 17510365
CTNB1 RUVB2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16699503 27684187 15829968 11080158 20603076
PLAK CNBP1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17353931 16189514 32296183 33961781
HDAC1 NFKB1 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
ERBB2 SRC â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
SRC ABL1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11494128 17474147 12522270 11781820 17318191
ABL1 EGFR â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 31980649 24658140 16273093 25402006 7678409
ABL1 P85A â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 1383690 16135792 8781408 17474147 8294442 16219545 19380743
AXIN1 APC â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16199882 22682247 10228155 29045831 18786926 20128690 19131971 26496610 10811618 9734785 29713058 23277359 17510365
AMER1 APC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23151663 24251807 17510365
AXIN2 APC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10966653 10911903 9554852
AF10 DOT1L â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 26496610 21103407 24981860 20431927 15851025 20203130
SRC EGFR â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 17284441 6169640
EGFR RHOA â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18955552 20937854 15156151
CADH1 EGFR â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 25241761 31980649 24189400 24658140 25402006 25468996 10969083
P85A EGFR â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21701776 25241761 16713569 7499252 19531499 22973453 25187647 8662998 16273093 25754235 7797556 31959764 16230374 7531698
1433Z EGFR â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 31980649 15225635 23956138 15389569 19531499 24658140 25402006 15657067
EGFR MET â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20624308 24189400 21918175 24362532 10722725 23866081 26551075
EGFR CTND1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 24797263 31980649 24189400 24658140 9535896 14996911 25402006 25754235 27316454 15657067
EGFR PLAK â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 24797263 31980649 24658140 9535896 25402006 14517306
EGFR HS90A â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 32669362 20029029 31980649 16849543 12471035 23956138 16024644 24189400 24658140 12006493 25402006
EGFR CTNB1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 9535896 24189400 9233779 11950845
EGFR HDAC6 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20029029 31980649 24658140 20133936 25402006
EGFR HS90B â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20029029 31980649 12471035 23956138 24189400 24658140 22939624 25402006 15657067
EGFR ERBB2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11500850 25241761 30898150 17486068 11526509 9461599 23866081 17426253 10572067 11500516 24557338 8665853 15657067 19060928 16516204 19650109 20211985 25315821 23436906 21278786 25898135 32669362 1346931 24189400 21044682 18803307 16843263 28369073 7531698 16713569 17148612 21203579 17307140 1706616 16207817 7797556 12354693 11408594
EGFR CAV1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16407214 19446582 22411794 31980649 12388423 24658140 15273741 25402006 16799092 9374534 34079125 12354760 10781609 15657067
EGFR MUC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21258405 31980649 11483589 16983337 24658140 25402006 11278868
EP300 HDAC6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15102857 19344692
SRC MUC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11483589 11152665 21798038
MUC1 CTNB1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11152665 11483589 9139698 9819408 12618757 11877440 12750561 15221004
LAP2 PKP4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 24550280 16203728 11821434 12047349 11711544
1433Z YAP1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 15161933 28628118 29069755 27684187 28205554 30472188 33961781 24255178 26578655 25670079
YAP1 SMAD7 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 25283809 22921829 12118366
YAP1 LATS2 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 17974916 21832154 21205866
PIN1 SMAD3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21988832 19920136 21685363 19122240
CBY1 CTNB1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 18334222 12712206 20096688 16713569
FYN GSK3B â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 17607942 15676027 15652488
AXIN1 SMAD7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 16601693
SMAD2 SMAD3 â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
HDAC1 SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10199400
SMAD3 ANDR â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11707452 11280774 12226080 16713569
HDAC1 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11306568 19049980 10575014
AXIN1 CTNB1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 10228155 27902311 30181396 24976009 20128690 12421363 17318191 19166851 18632848 19131971 16890161 26496610 20531388 23892894 32533114 18593713 21242974 22682247 19223551 9734785 17510365 16199882 23959799 12805222 29045831 22509369 29789528 34079125
AXIN1 GSK3B â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 25241761 17601533 21988832 10228155 24976009 30181396 20128690 12511557 17318191 16293724 23455922 28546513 17318175 19303846 18632848 19131971 16890161 26496610 23892894 23602568 22613765 18593713 29568061 21242974 22682247 19759537 11738041 22270359 24451375 9734785 32707033 21502811 17510365 10481074 16199882 26912724 23959799 29045831 22509369 29789528 19202075 12584189
APC2 AXIN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 9601641 10980707
DVL1 GSK3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10428961 16914735 20837657
HIF1A HDAC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17273746 11641274 16511565 21148070 24015760
FBW1A SKP1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16189514 25416956 10644755 10228155 19933270 19061640 30254149 16275325 12609982 17283138 17215248 24469040 22388891 12820959 9990852 31467278 10023660 10918611 14706645 19159283 11483504 9660940 25900982 28614300 26474281 31210753 15536641 30728155 17463251 10514433 24912152 25632159 20596027 10074433 22632967 29863914 24811168 10531035 23607312 29997244 25332235 30267325 27705803 33961781 32350066 15070733
CYBP SKP1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28196083 16189514 25241761 11389839 27099442 22295074 29099417
FBW1B SKP1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 10644755 12165731 30254149 25609649 21145461 19159283 26496610 25900982 29150431 20596027 10230406 19615732 17510365 10321728 24500709 29435596 25515538 25332235 27705803 33961781 32350066 15070733
ERBB2 RHOA â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18955552 20937854 15156151
BCL9 CTNB1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 24360964 15294866 11955446 34079125 31073027 17052462
HIF1A HS90A â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16189514 17442277 15147973 20724477 16507982 26517842 18538669 17237281 14726529 9079689 14764593 23722539 20668552 21413014 24844779 25204544 15319539 24648344 17244529 19491109 33550096 16951198
NFKB1 HIF1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18498249 17898080
ANDR SRC â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 24728074 15062576 11032808 15466214 15027889
SRC ERBB2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 22973453 11940572 17875712 19372587 21075308 29720121 7542762 7797556 19704002
SRC MET â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 24034250 20624308 9837958 24728074
IKKB NFKB1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 25241761 16713569 11297557 11976329 10469655 11158290 22536447 12482991
NFKB1 IKKA â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 14743216 16713569 11297557 11976329 10469655 25609649 12482991
NFKB1 FBW1A â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 26112410 10835356 9990852 11953428 25900982 33961781 11158290 12482991 22388891
USP9X CTNB1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 26717875 27783990 10620020 34097426 31073027 14742711
RXRA GSK3B â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
DNMT1 GSK3B â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
ERBB2 CTNB1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 7702605 11245482 11950845
ERBB2 HS90A â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 25036637 24189400 16144943 23995768 24658140 22315411 26804907 18655187 21503962 22939624 21812426 12006493 17239458 20159553 11071886 20558745
HNF4A CBP â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 18552123 16713569 10882110 9434765 10085149 9792714
RXRA HNF4A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10744771 11027556
APC2 CTNB1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 23840886 16510875 10074433 10021369 9823329
TCF7 LEF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15473860 17335794 11326276
CBP ANDR â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12810069 16713569 9822653 20541699 33640491 9482849 15691881 34585037
ANDR CTNB1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 22865883 21885566 16713569 12799378 11792709 15060161 11916967 12944908 22187462 21741601 12588987 10987273 15256534 14593076
ANDR HS90A â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20048054 16713569 21157430 32206096 27903893 17974989 1540595 26342197 26196320 25500540 19706771 19805354 17353003 1525041
CADH1 CTND1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12427869 12640114 10409703 22850631 7876318 23180380 10629228 22715382 11226248 21670201 10931041 7542250 29207493 19114997 7651399 19711372 24424122 20371349 25466890 25468996 12707304 9535896 10225956 33961781 22752307
CTNA1 CADH1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 10381631 22750944 11226248 11960376 19016843 7542250 9326449 25468996 16212417 8227214 9233779
TF7L2 PLAK â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16306047 32296183 11711551
FBW1B FBW1A â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 16189514 10644755 25900982 33961781 31406304 29150431 19615732
FBW1A CTNB1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 22017875 19956254 10228155 30181396 26091241 19061640 17053147 27001857 24501426 33482471 25873176 21829575 18650423 24561623 24469040 12820959 19966869 33159601 9990852 10023660 30918250 14706645 25900982 18354482 20531388 16376880 25149538 27316454 16798748 14516475 21466614 19150432 20851351 22682247 12114015 18805092 34352208 22912335 18851830 28018973 23514615 24912152 32051583 11818547 24451375 24464578 10074433 30804013 29674637 30923315 26506240 19053519 25515538 31868589 30926793 22730322 29789528 30242702
PSN1 CTND1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28069439 11226248 10208590
IQGA1 CTNB1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11734550 12446675 22519731 22662192 16622255 27684187
FHL2 CTNB1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12466281 16713569 27684187
CTNB1 MAGI1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 34079125 27684187 10772923
PLAK CTNA1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 7890674 9110993 16189514 25241761 9762469 20936779 14517306 34079125 22939629 7650039 26344197
VINC CTNA1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16189514 9700171 23292143 26496610 34079125
CD5R1 CTNB1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 10753743 16029324 11168528
ITF2 CTNB1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17983804 23449499 11713476 12944908 16230076 21743491 17318191 18281465 25402006 16724116 23671189 30691485 22155184 33643786 29463646 28829046 31286874 17909039 15060161 12727872 15331612 19114997 24532795 17412698 17050667 22080605 29361949 16630820 17072306 17220880 15665104 24876153 15525529 21103407 24798214 12657632 20126258 26123998 17875931 17962194 11713475 33754069 29374067 16007074
TF7L1 CTNB1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11266540 29540185 11136974 15327769
CTNA3 CTNB1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 25241761 11590244 33961781 23136403 23718855
RUVB1 CTNB1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 9843967 18087039 16510875 16510874 27684187
CTNB1 PLAK â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 25241761 26496610 9535896 34079125 11712088 27684187 17510365
PLAK CADH2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 14625392 8074697 12604612 17098867 1639850 22939629 7650039
EP300 HDAC1 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
DNMT1 HDAC1 â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
HNF4A HIF1A â—¼   PROTEIN_INTERACTION 0.91 0.91 HIPPIE 12097158 14741200
APC GSK3B â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
AXIN1 GSK3A â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
AXIN1 LRP6 â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
KC1A CTNB1 â—¼   PROTEIN_INTERACTION 0.92 0.92 HIPPIE 29674637 34352208 27684187 11955436 31462704 12000790 17510365
AXIN2 GSK3B â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
CBP IKKA â—¼   PROTEIN_INTERACTION 0.93 0.93 HIPPIE 17434128 14597638 11971985 12789342
EGFR SRC â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
CBP SMAD3 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 19589780 27566588 10497242 18003620 17283070 15467747 33323411 15849193 15990875 15750622
P85A CTNB1 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 10477752 25241761 11716761
EP300 SMAD3 â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
ERBB2 EGFR â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 5218411 16516204
DVL1 DVL3 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 32296183 10330181
PAXI SRC â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 10085298 16713569 7534286 14665621
SRC CTNB1 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 23246962 11279024 22056988
P85A ERBB2 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 12896906 9756944 22973453 16843263 16273093 21075308 1351056 7531698
APC CTNA1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 25241761 7651399 29045831 8259519 26496610 20936779 34079125
HIF1A EP300 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 17382325 5219810
PSMD4 PSMD1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 19781552 16990800 22863883 33961781 30479383 22939629 26344197
LAP2 SMAD3 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 18729074 17591701 12650946 18003620
AHR HS90A â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 9390191 8089152 11013261 7961671 18806268 10617682 9083006
CBP CTNB1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 26123998 16476742 33190089 11973335 23273993 19223551 28648376 30836930 18347063 26657156 21751375
CADH1 PLAK â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 8207061 7890674 11226248 27684187 8074697 9535896 7542250 1639850 25468996 14517306 10959047 22375065
CTNA2 CTNB1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 17679699 33961781 26344197
SMAD7 YAP1 â—¼   PHYSICAL_INTERACTION 960.0 0.96 STRING 36370105
AMER1 APC â—¼   PHYSICAL_INTERACTION 962.0 0.96 STRING 36370105
FYN SRC â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
APC PLAK â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 11707392 25241761 7651399 8074697 26496610 9298899 11348595 11136974 20936779
APC GSK3B â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 11166179 29045831 21118991 8638126 11251183 23602568 29568061
SRC EGFR â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 31980649 8845374 21573184 25402006 7506422 10075741 19704002 10971656 23175185 10777553 22227249 20935677 20624308 21268077 17158602 24189400 9020193 16713569 22973453 11983694 24658140 28065597 21278788 17284441 7797556 20333651 7527393 10358079
HIF1A EP300 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 15280364 19589782 16543236 11823643 22807441 19666581 16189267 18047470 15342390 12042299 19680224 22735262 23448368 26135796 23618863 14691445 19696166 11959990 27320910 16847340 24821806 22789427 17906695 8917528 20620956 20000859 15261140 16081065 12778114 22219185 15154850 25192544 22075993 19071119 22908229 19940151 21187066 24421387 23880760 11940656 23966271 26826385 26944191 12588875 23746844 11063749 27808477 19074848 20603618 15155277 18268343 20829524 21148070 12914934 17502379 22684029 17382325 26751287
ASPP2 YAP1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 16713569 27684187 11278422 10358088 25436413 25796446 25751139 26933062 30472188 24255178 31636332 24366813
HDAC1 DNMT1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 22274925 20613874 26794444 10615135 10888886 17707923 17934516 15870198 21670149 27593931 17967891 12473678 23708667
HDAC1 NFKB1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 25241761 12972430 17962807 24448807 11931769 14678988 16319923 17827154
HIF1A CBP â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 22219185 15154850 21602890 15615775 16543236 18426857 15527772 11959977 9887100 19880525 27934968 16579968 8917528 11983697 17382325 10202154 25517638
GSK3B CTNB1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 19576224 12051714 25241761 19107203 25897075 10228155 27902311 30181396 33431799 19061640 16039586 8638126 21743491 17318191 11251183 27684187 31286874 19303846 10330181 23602568 11835406 29568061 11193155 12114015 18687691 34352208 26359353 11818547 24451375 10074433 30711629 17510365 30923315 29045831 16365045 29789528 12000790
LAP2 ERBB2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 11278603 22564389 10878805 12444095 12379659 25288731
CADH1 CTNB1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 17057644 12640114 22056988 22850631 19016843 7876318 12830000 12634428 11113628 11401320 11254878 7954478 23180380 27684187 8227214 10381631 16574648 22715382 11226248 17909039 31286874 11245482 11960376 17220478 9819408 25344754 7542250 9512503 12061792 18593713 15023525 10772923 16125672 28966723 24424122 25466890 9405455 9326449 25468996 19223551 16212417 18593907 24798214 22375065 12169098 22158051 9535896 16983094 11348595 33961781 29789528 22752307 11712088 9233779
CADH5 CTNB1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 22720799 17057644 28514442 23243000 22519731 12413882 12003790 18287330 33961781 20123964 9434630 20224040 18662404
TF7L2 CTNB1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 22056988 26350900 27902311 29540185 12861022 11713476 16230076 16724116 16569639 27684187 22155184 30918250 19443654 21670201 15684397 18772112 30833792 19816403 17050667 16630820 11713475 16306047 19304756 17914096 22304967 17283121 20126258 22014570 19202075 34079125 16442529
PAXI VINC â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 9054445 7525621 30120307 10330411 7534286 20308429 34079125 8922390 26344197
IKKA IKKB â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 25241761 11080499 9914500 9346241 9346485 11585904 21784860 25852190 25748427 12210728 21903422 14743216 10733566 12244103 9346484 12486103 11971985 21575199 11057907 32707033 16286467 16129692 20434986 11864612 16713569 23016877 20932476 10968790 30500824 17693255 33961781 9751060 16319058 9721103
CTNB1 CTNA1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 12640114 9110993 19941816 17072306 27684187 26496610 17098867 7706414 9512503 33961781 9762469 34079125 14517306 24509793 7954478 15492215 17052462 26344197
CNBP1 CTNB1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 21885566 15893313 17072306 26912724 20211142 17353931 10898789 29540185 18287330 33961781 27684187 12417602 12408825 17510365 12408824
CTNB1 PSN1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 17360711 11193155 11226248 10092585 10037471 16306047 12070348 10341227 16126725 9852041 11168528 9738936
HS90A HS90B â—¼   PROTEIN_INTERACTION 0.98 0.98 HIPPIE 25036637 31536960 20353823 26496610 22863883 26344197 33961781 21360678 19875381
EGFR ERBB2 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
APC CTNB1 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 19576224 22056988 25241761 27902311 15327769 9707618 8638126 17318191 11251183 15327768 27684187 10545404 15355978 8259519 16510874 26496610 32533114 11533658 22682247 7890674 11166179 11972058 11707392 23840886 11712088 15525529 34079125 16212417 33858476 17510365 21664290 9482734 29045831 33961781 12628243 9286858 12000790 10773885
LEF1 CTNB1 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 33431799 29540185 11751639 21743491 27684187 10890911 15768032 15684397 16510874 15728254 8757136 11835406 12556497 16510875 15525529 19223551 20123964 17510365 18077326 12077367 16204248 17517646 29374064 10958684 9419974 12748295 18296023
CTNB1 TX1B3 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 12874278 33961781 18835279 20211142
LATS2 YAP1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
EP300 HIF1A â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PSMD1 PSMD4 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
AXIN1 GSK3B â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ABL1 YAP1 â—¼   ENZYMATIC_REACTION ✅ 12.0 1.0 ACSN 10837221 11804596 11971963 12628935 12709442 15459660 18835194 19788416 21051857 21199784 21435002 9168117
FYN ABL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 12522270 16787943 17570479 16912036 16076903 17474147 11847100
SRC ABL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 44.0 1.0 Omnipath 19901323 10964922 16497976 20841568 16787943 17570479 17318191 11847100 10500097 12522270 18691976 11494128 11781820 16076903 20168609 12748290 16464493 12445832 19369195 17474147
ABL1 MUC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 15471854 7664271 14521915 20841568 16888623
ABL1 YAP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 29.0 1.0 Omnipath 25361080 19788416 21199784 29449692 18955976 21051857 18280240 21435002 18701449 27807512 20841568 21214929 21945154 29179447 15459660
ABL1 MET â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 29.0 1.0 Omnipath 9826708 12766170 9391119 9242692 10506185 8547236 10069803 7687741 10490849 11741535 21777671 8906793 12475979 9444958 7513258 7961992 15475459 9252406 7838524 7731718 8662889 7708691
ABL1 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 55.0 1.0 Omnipath 24430869 15192046 33889303 16273093 16943190 14760089 29880877 15618223 33574089 8910327 12631709 25173817 25402006 20841568 33947961 34107301 34469737 19915609 32019812 2022651 34290403 33707748 15329413 7678409 9733788 8490966 28338646 3263271 15901825 2022652 10069801 7506413 24658140 8408058 34385595 31980649 1314835 7741752 18668345 28724430 12648464 25073158 26079946 34155348
ABL1 CAV1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 18083107 17389395 11094059 19534553 8632005 12531427 27292265 24632723 11075810 12036959 15592455 20841568 15951569 20808760 16151024
APC AXIN1 â—¼   PHYSICAL_INTERACTION 26.0 1.0 ACSN 10421629 10581160 11487578 11955436 11967263 12051714 12554650 15001769 15327768 16039586 16288291 16940750 17143292 17318175 17936032 19619488 19751508 20006983 20705860 22270359 23343194 24023259 25730849 7542250 8638126 8666229
APC BCL9 â—¼   PHYSICAL_INTERACTION 33.0 1.0 ACSN 11274345 11955436 11967263 12051714 12711682 15001769 15327769 15834423 16039586 16510874 16547505 16940750 17143292 17439715 17936032 19216735 19506021 19619488 19623618 19751508 20006983 20705860 20964627 21285352 21681822 22270359 23343194 24023259 25730849 26587781 7542250 8545107 8666229
APC AXIN1 â—¼   PROTEIN_INTERACTION 26.0 1.0 ACSN 10421629 10581160 11487578 11955436 11967263 12051714 12554650 15001769 15327768 16039586 16288291 16940750 17143292 17318175 17936032 19619488 19751508 20006983 20705860 22270359 23343194 24023259 25730849 7542250 8638126 8666229
APC BCL9 â—¼   SHARES_COMPLEX 33.0 1.0 ACSN 11274345 11955436 11967263 12051714 12711682 15001769 15327769 15834423 16039586 16510874 16547505 16940750 17143292 17439715 17936032 19216735 19506021 19619488 19623618 19751508 20006983 20705860 20964627 21285352 21681822 22270359 23343194 24023259 25730849 26587781 7542250 8545107 8666229
GSK3B APC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 16944320 11166179 16799642 11967263 14663202 8524413 12554650 8638126 17910481 15327768 10581160 11487578 17318175 15465828 10228155 15020233 10421629 10698523 9832503
AXIN1 APC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 16199882 20128690 19131971 11297546 9554852 22682247 10228155 26496610 23277359 10811618 9734785
CAV1 EGFR â—¼   DOWN_REGULATES ✅ - 13.0 1.0 ACSN 11102446 17517963 18458534 19411448 20855962 21051947 21150282 21729786 22411312 22874531 23907124 25364523 26828520
NFKB1 EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 14678988 18367518 12469217 17881446
SRC EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 232.0 1.0 Omnipath 16414009 17081983 25958313 16943190 15618223 19935697 19305428 25402006 24797263 29285309 7488034 15592458 17389395 16461772 20562096 19275932 17897439 15899872 17570479 2803273 23636329 23246962 25505586 23175185 15615697 23349873 16849545 25356505 11983694 24189400 11756413 25748412 26325669 26150526 14512423 18789131 14750954 31978707 25573954 27495374 20071362 18707149 28759036 16729043 26494466 27716204 25537504 17237269 18687633 25884760 29036202 26936397 17575160 20926745 20935677 15282306 23702846 15476828 9069259 19336574 20421302 15660394 23866081 19377510 9777370 22426783 29321659 33706413 25841779 19840943 18669648 12397069 16843263 18957516 34088769 25077442 14963038 19836242 17653080 19625610 16936701 11960379 15548697 18295415 17523611 21268077 20333651 21399647 23376850 11250711 23942551 19704002 22927910 11160627 31952541 10777553 17016520 2543678 19258037 33883672 17646646 28102297 23873690 26771606 21573184 23119029 19151764 16713569 7797556 25955608 15302935 20407013 28513565 23119185 9990038 21080693 20190765 25347738 14630916 15708852 21822308 20628053 25301722 24658140 19690143 27564112 20802523 29124875 33657368 12101233 21787862 14764607 17284441 12878163 26290602 15951569 16543144 15212693 17971399 14523024 10971656 21278788 8845374 22430206 18083107 29641465 18234969 18460189 17551925 22957061 26571308 17043637 20371672 10358079 16799092 19154417 23066441 28065597 12842895 18180459 17158602 18271526 15657067 25159151 34367939 24919575 10075741 25366117 24349301 17561374 16862179 20215522 31980649 24335899 16037379 18451158 14530278 16505275 12063263 23449029 11311660
PTEN EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 16288286 10648629 17218262 12040186 15584861
PTPRJ EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 19836242 9115287 19167335
EGFR MUC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 11483589 11152665 31980649 17889671 21258405 24658140 14521915 25402006 16983337 15212693 11278868
EGFR ERBB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 65.0 1.0 Omnipath 17081983 16207817 21044682 17148612 24557338 16713569 21203579 10233167 20471394 17389395 17486068 21278786 11500516 11279155 11500850 17426253 16843263 19650109 25241761 24189400 15657067 17307140 18803307 1706616 12354693 10572067 24355130 11408594 19060928 12648464 16516204 15951569 23436906 20211985
EGFR HDAC6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 20133936 31980649 22896792 20029029 24658140 21151618 25402006 23084749
EGFR CAV1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 17145710 31980649 22411794 9374534 19446582 16799092 12388423 15657067 24658140 19625610 16407214 18789131 25402006 15951569 10781609 16332692
SRC EMD â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 25008017 24609268 19789182 29684168 24365856 17637040
EP300 SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 31.0 1.0 Omnipath 21988832 23331499 9169454 12237408 10199400 11264182 7878020 8047140 12958365 19171760 11371641 16027720 17074756 17469772 21269274 15623506
EP300 HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 75.0 1.0 Omnipath 24821806 12573436 17145710 16847340 12588875 19589782 11940656 25192544 11959990 18519678 23448368 22219185 11823643 12042299 15342390 23746844 19071119 19680224 27808477 15154850 19696166 8917528 17906695 18268343 22735262 21148070 15261140 19940151 23880760 22807441 35430356 14691445 12914934 20000859 12778114 26751287 16081065 22789427 16543236 24421387 17382325 17502379 22684029 21187066 19074848 23618863 23966271 20603618
EP300 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 9843571 11134049 12743039 15133024 15824515 15623506 16876108 21567395 16109717 17074756 20564330 10497242 15588252 17469184 15345715 11058129 10575014 16862174
EP300 SMAD7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 23331499 12408818 10887155 15831498 21269274
SRC EPHA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 24457997 28957431 26788993
HIF1A FOXM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22831955 19097132
HIF1A FOXO3 â—¼   ENZYMATIC_REACTION ✅ 66.0 1.0 ACSN 10102273 10428030 10428780 10435632 10804084 10823814 11557773 11559532 11744734 11756417 11884613 12402042 12676992 12743597 14672622 14684737 14699081 14762718 15024076 15059920 15199147 15240700 15312748 15369676 15379897 15545625 16110315 16126909 16127144 16517405 16517406 16585195 16782875 16888645 17143338 17418790 17533374 17785433 18054315 18056423 18158893 18718909 19211554 20028863 20427344 20535745 20855962 21051947 21765015 22006996 22841746 22850421 22988108 24006507 25043024 25103413 25732824 7493931 7500013 7508926 8089148 8702901 8955077 9486205 9525945 9707622
HIF1A MUC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22869720 19549898 19141292
GSK3B MUC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 9819408 11152665
SRC MUC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 11483589 11152665 14521915 21798038 15212693
LEF1 TRRAP â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 9843967 14695187 16510874 15829968 11080158
LATS2 YAP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 36.0 1.0 Omnipath 22863277 20048001 18413746 24525530 15302935 19797269 17974916 18640976 18369314 29179447 18669648 25670202 26578655 29680477 18565851 21233212 21041410 18158288 19919647 18220336 21832154 22658639 21041411 24976283 26598551
YAP1 SMAD7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 23331499 22921829 12118366 25283809
LEF1 AXIN2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 19751508 7542250 8666229 11955436 11967263 22270359 16940750 12051714
HDAC1 AXIN2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 21734722 17666529 15576399 22761862 22290435 19923891 20682799
AXIN2 GSK3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 15611123 10966653 10911903 888800000547 9554852 22745173 9566905 22322943
AXIN1 PIN1 â—¼   PHYSICAL_INTERACTION 22.0 1.0 ACSN 11274345 11283614 16713974 16940750 17558397 17873522 19131971 19366350 19751508 19836308 20027199 20237412 20551172 20581311 20713526 21406394 2191300 22067385 22270359 23732914 25002027 26885856
AXIN1 PIN1 â—¼   SHARES_COMPLEX 22.0 1.0 ACSN 11274345 11283614 16713974 16940750 17558397 17873522 19131971 19366350 19751508 19836308 20027199 20237412 20551172 20581311 20713526 21406394 2191300 22067385 22270359 23732914 25002027 26885856
CDC73 LEF1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 19148484 22982193 16630820 21726809
FYN PTPRC â—¼   ENZYMATIC_REACTION ✅ 17.0 1.0 ACSN 10591186 10648627 12218089 12414720 12731048 19290918 19909365 20814939 21378271 22683124 22863785 23620508 23886063 24440149 25312647 27192565 9738502
PTPRC FYN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 1985196 8980254 11909961 1464315 1533589 9535845 16713569 9368621 12589038
FYN PTPRF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12496362 18854310
FYN CAV1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 33.0 1.0 Omnipath 9252391 29371975 11805080 12925753 21705803 12529448 11075810 15692085 14992595 8632005 10592173 16943184 12921535 16332692 12135605 20228056 15466865 33804982 24632723 33928090 18347068 34321069
SMAD3 SMAD7 â—¼   PHYSICAL_INTERACTION 13.0 1.0 ACSN 11279127 11792802 12702545 12809600 15265520 16179589 16713975 18768831 21042762 21614932 22331441 23784029 8515656
SMAD2 SMAD7 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 11074002 11279127 15265520 16179589 16713975 21042762 21614932 22331441 23784029 9670020
SMAD2 SMAD7 â—¼   PROTEIN_INTERACTION 10.0 1.0 ACSN 11074002 11279127 15265520 16179589 16713975 21042762 21614932 22331441 23784029 9670020
SMAD3 SMAD7 â—¼   PROTEIN_INTERACTION 13.0 1.0 ACSN 11279127 11792802 12702545 12809600 15265520 16179589 16713975 18768831 21042762 21614932 22331441 23784029 8515656
SMAD2 SMAD7 â—¼   DOWN_REGULATES ✅ - 10.0 1.0 ACSN 11074002 11279127 15265520 16179589 16713975 21042762 21614932 22331441 23784029 9670020
SMAD3 SMAD7 â—¼   DOWN_REGULATES ✅ - 13.0 1.0 ACSN 11279127 11792802 12702545 12809600 15265520 16179589 16713975 18768831 21042762 21614932 22331441 23784029 8515656
SMAD3 SMAD7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 10823886 15183844 12761881 10887185 10973944 10839991 10753944 10843994 15579469 10559222
SMAD2 SMAD7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15183844 10887185 10753944 10843994 10559222
SMAD7 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23331499 21071413 9892009 26555259 9892110
SMAD7 SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23331499 17438144 21071413 9892009 9892110
SMAD3 SMAD2 â—¼   PHYSICAL_INTERACTION 41.0 1.0 ACSN 10454538 10964912 11007770 11013220 11074002 11279127 11283613 11283614 11792802 12545156 12702545 12809600 15001984 15095404 15155580 15265520 16179589 16713975 17055429 17550342 17705132 18353785 18768831 19815509 19901969 20027199 20713526 21042762 21252118 21614932 2191300 22331441 23140366 23338822 23869868 8515656 9312026 9389648 9618481 9670020 9865696
SMAD3 SMAD2 â—¼   PROTEIN_INTERACTION 41.0 1.0 ACSN 10454538 10964912 11007770 11013220 11074002 11279127 11283613 11283614 11792802 12545156 12702545 12809600 15001984 15095404 15155580 15265520 16179589 16713975 17055429 17550342 17705132 18353785 18768831 19815509 19901969 20027199 20713526 21042762 21252118 21614932 2191300 22331441 23140366 23338822 23869868 8515656 9312026 9389648 9618481 9670020 9865696
SMAD2 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 21988832 26186194 12543979 9111321 15084259 9311995 25878769 18729074 12700238
SMAD2 LEF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 10890911 21071413 18988627
DVL1 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23331499 15888125 12650946 15955531
AXIN1 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11438668 23331499 18988627
GSK3B SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 23331499 18172167 21071413 21310903 23077590 28756206 19114991 19002158
SMAD3 LEF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23331499 10890911 21071413 18988627
RHOA PTEN â—¼   ENZYMATIC_REACTION ✅ 32.0 1.0 ACSN 10953004 11698448 11729192 11739775 11992112 12194823 12361600 12740575 12778124 14657501 14744429 15761148 15793569 17517963 18037882 18423981 20008297 20351293 20535745 21178402 21642958 21840487 22949611 24857661 24919149 26885855 27048821 27066895 7479854 9362522 9660866 9822605
SRC PTEN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 24830552 22891331 12869565 21532586
GSK3B PTEN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 25.0 1.0 Omnipath 20080742 19797085 16107342 12040186 23379765 16611981 10671551 16039586 17570479 12615961 25763354 19575820 17444818 20537194 26339505 23210979 17052453 18455992 16371461 11274345 12297295
MAGI2 PTEN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11035045 10760291
PTEN IGF1R â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 16288286 10648629 17218262 12040186 15584861
DVL1 AXIN1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11336703 17529994 18077588 17569865
BCL9 AXIN1 â—¼   PHYSICAL_INTERACTION 28.0 1.0 ACSN 11955436 11967263 12051714 15001769 15576399 16039586 16288291 16940750 17143292 17306568 17666529 17671186 17936032 19619488 19623618 19751508 20006983 20705860 21151179 21285352 22270359 22290435 22761862 23343194 24023259 25730849 7542250 8666229
AXIN1 DVL1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 ACSN 10428961 16288291 16940750 19751508 22270359 8666229
BCL9 AXIN1 â—¼   SHARES_COMPLEX 28.0 1.0 ACSN 11955436 11967263 12051714 15001769 15576399 16039586 16288291 16940750 17143292 17306568 17666529 17671186 17936032 19619488 19623618 19751508 20006983 20705860 21151179 21285352 22270359 22290435 22761862 23343194 24023259 25730849 7542250 8666229
AXIN1 DVL1 â—¼   SHARES_COMPLEX 6.0 1.0 ACSN 10428961 16288291 16940750 19751508 22270359 8666229
BCL9 AXIN1 â—¼   ENZYMATIC_REACTION ✅ 28.0 1.0 ACSN 11955436 11967263 12051714 15001769 15576399 16039586 16288291 16940750 17143292 17306568 17666529 17671186 17936032 19619488 19623618 19751508 20006983 20705860 21151179 21285352 22270359 22290435 22761862 23343194 24023259 25730849 7542250 8666229
GSK3B AXIN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 102.0 1.0 Omnipath 20128690 16944320 11738041 20043192 12511557 11967263 16890161 22613765 14663202 23602568 8524413 24451375 19303846 12554650 8638126 22509369 18593713 16199882 21988832 23331499 19759537 10428961 9482734 22270359 19202075 17570479 16293724 15327768 10581160 17318191 11487578 22773187 26496610 16568235 17318175 19131971 15465828 26912724 25241761 24976009 21242974 22682247 10228155 23579495 12584189 23959799 15020233 10421629 10488109 11278246 9501208 18632848 10481074 10535959 10318824 9554852 17601533 9832503 21502811 9734785 23455922
LRP6 AXIN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 20128690 23331499 8666229 12897152 10428961 24976009 16890161 18632848 22682247 23959799 16340998 18988627 19107203
DVL1 AXIN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 12556519 11278246 10862053 10330403 10330181 10428961 9482734 10196136 11027605 18339531
AXIN1 GSK3A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 9501208 9601641 9482734 11707456 10196136 17318175
DVL1 LRP6 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17234765 18077588 14636582 22411803
DVL1 GSK3B â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11336703 17529994 18077588 17569865
NFKB1 SKP1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 9990852 10514433 9859996 9990853 7628694
LRP6 DVL3 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17234765 18077588 14636582 22411803
GSK3B LRP6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 22357953 23331499 19107203 21606194 16890161 21709260 16340998 16365045 19366350 21406690 16341017 17318175
GSK3A LRP6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 24642411 21606194 21709260 14731402 20229235 30824926 16365045 19366350 21406690 17318175
BCL9 LEF1 â—¼   PHYSICAL_INTERACTION 20.0 1.0 Reactome 12163411 16169192 11955446 18347063 17458864 22186018 15294866 16005293 16510874 19487454 9490669 17425782 19493659 18498752 17052462 22190459 18404694 11988739 17428831 22617422
NFKB1 HIF1A â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 17272744 18393939 21725609 23178297 23572150
HIF1A CAV1 â—¼   ENZYMATIC_REACTION ✅ 16.0 1.0 ACSN 10804084 16110315 16127144 17533374 20427344 20535745 20855962 21051947 21765015 22006996 22850421 22988108 24006507 25043024 25103413 25732824
HIF1A MET â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16099863 17028975
CAV1 SRC â—¼   DOWN_REGULATES ✅ - 13.0 1.0 ACSN 11102446 17517963 18458534 19411448 20855962 21051947 21150282 21729786 22411312 22874531 23907124 25364523 26828520
ERBB2 SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16769082 19617202 11940572 12753909 21075308 7542762
PTPRJ SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18936167 20345711 15735685 10428027
SRC MET â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 24728074 24034250 9837958 17570479
SRC HNF4A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 16713569 22308320
SRC CAV1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 65.0 1.0 Omnipath 20201820 23469926 24755228 24525631 15592455 27259249 17979878 19409422 11075810 17389395 14992595 18578522 11094059 11451957 24244013 8632005 24131997 12921535 21324536 16332692 8621645 18815812 27170175 17517963 12531427 24632723 23091071 19625610 18789131 24502576 17016520 20107068 21382479 24364863 25937636 19604397 23280667 16713182 22596063 26169283 8910575 17190831 18707149 25097454 12036959 18176934 15212693 18400052
SRC RXRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10322133 23331499 15140878
SRC IGF1R â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 17389395 15212693 18691976 7559478 7493944 7537849 20068231 23472139 8550552 17016520 8940173 9480911
DNMT1 FGFR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17172825 18704159 21779870 21150308
GSK3B NFKB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 26999213 12871932 11425860 24618402 18669648 17693123
GSK3B DVL3 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11336703 17529994 18077588 17569865
BCL9L LEF1 â—¼   PHYSICAL_INTERACTION 20.0 1.0 Reactome 12163411 16169192 11955446 18347063 17458864 22186018 15294866 16005293 16510874 19487454 9490669 17425782 19493659 18498752 17052462 22190459 18404694 11988739 17428831 22617422
PTPRJ MET â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 12370829 15475459 19167335 12475979
CTNB1 CADH2 â—¼   PROTEIN_INTERACTION 1.0 1.0 HIPPIE 17057644 18302981 12077367 14625392 12604612 12151522 17098867 21357690 33961781 34079125 25143387 11835406 17679699 17510365 18948590
RUVB2 RUVB1 â—¼   PROTEIN_INTERACTION 1.0 1.0 HIPPIE 28514442 25416956 10524211 18087039 20211142 25636407 17643375 19433865 32296183 17721549 16230350 20603076 29323271 26264872 20371770 17353931 17636026 10966108 22939629 17157868 29892012 28561026 22863883 33961781 25437307 18358808 11080158 26344197