Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
SMAD4 SNAI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18618014 18832382
SMAD3 GLI2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19797115
WWTR1 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21084559 18568018
FBXW2 CUL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14603323 5216801
NEDD8 CUL1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 intact 0806155105 18723677
SKP1 NFKB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17145710 14743216
SNAI1 UBP37 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 33391500 31911859 31998374
CENPW FBW1A â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 27861801 30267325 29863914
FOXN3 FBW1A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
FOXN3 FBW1B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
FBW1A MPRIP â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
RIPK4 RBX1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 29435596 26972000
TFAP4 TRIB2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
FBW1B YAP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21900206 22017875
ARI1 UHRF1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
LAP2 SMAD4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 12650946
RIPK4 CUL1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 29435596 26972000
KHDR2 CUL1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
T22D4 CUL1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
ZN704 CUL1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
UBP37 SKP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26299517 23027877
CSN6 SKP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 19295130
RIPK4 SKP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 29435596 26972000
P53 SKP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22653443 23443559
CD4 FBW1A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 16189514 9660940
FBW1A DOCK1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 25900982 32203420
FBW1B EED â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
FBW1A EED â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
APBA2 FBW1B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
APBA2 FBW1A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
ARI1 FBXW2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
FBW1A BTG3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
FBW1A CNOT2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
PRIC3 FBW1A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
GP161 FBW1A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
LSP1 FBW1A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
I17RD FBW1A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
PKHG5 FBW1A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
STIL FBW1A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 29445034 26638075
3BP5L FBW1A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
KHDR2 FBW1A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
KIBRA FBW1A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24366813 33961781
SPT20 FBW1A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
FBW1A BACH â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
FBW1A RLGPB â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
FBW1A GCP6 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
FBW1A PHLP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19797085 23440515
FBW1A MELPH â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
FBW1A KI20A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
FBW1A MYO10 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
FBW1A PRP16 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
FBW1A TB182 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
FBW1A CAHD1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
FBW1A GCP4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
FBW1A EMAL5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
FBW1A GCP5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
SUZ12 KHDR2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
SPT20 FBW1B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
I17RD FBW1B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
ZBT46 FBW1B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
GP161 FBW1B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
KIBRA FBW1B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24366813 33961781
PKHG5 FBW1B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
PRIC3 FBW1B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
3BP5L FBW1B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
LSP1 FBW1B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
FBW1B PRC2A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 25515538
PRIC3 GCP4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
PRIC3 NDK7 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
PRIC3 GCP6 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
SPT20 UBP47 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
FBW1B APC â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 25900982 25515538 28514442 33961781
KEAP1 NF2L1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 29255090 21988832 30126895 21262351 24127568 16687406
P53 RBX1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22653443 30349055 23443559
P53 SMAD3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 12732139 23687300 24157709
MPIP1 SMAD3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 15798217 21988832
SMAD3 FBW1A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 11359933 14988407
NEDD8 FBW1B â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 25900982 21145461 25332235
FBW1A AEBP2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 26091241 33961781 28514442
FBW1A EZH2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 24469040
SPXN3 FBXW2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
FBW1B SUN2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 25515538 25332235 30833792 25900982 33961781 19615732
FBW1A LAP2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 25900982 26056141
RASF5 FBW1A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 25416956 25217643 26871637
ZBT46 FBW1A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
MK14 FBW1A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 34703820 23532963 20797629
ZC12A FBW1A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 21900206 24270572 21988832
B2L11 FBW1A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194 23912711 19150432 22388891
INAR1 FBW1A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 18056411 33961781 21173164
IKKB FBW1A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 11158290 20797629 19656241
DLDH FBW1A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
SPXN3 FBW1A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
WBP1 FBW1A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
T22D4 FBW1A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
FBW1A PRC2A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 25900982 26091241
FBW1A GGNB2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 25900982 26091241
FBW1A MXI1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 29507620
FBW1A PR15B â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 25900982 26091241
FBW1A GBF1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 25900982 29898406
FBW1A NUAK2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 24785407
FBW1A NF2L1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 25900982 29941490
FBW1A ZN704 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 26091241 33961781 28514442
FBW1A RIPK4 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 26091241 26972000 33961781 29435596
FBW1A EGFLA â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 25900982 33961781 28514442
FBW1A FNIP1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 25900982 26091241
FBW1A DLG5 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 25900982 31787846
FBW1A SUZ12 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 24469040
MK14 UBP47 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
IKBB FBW1B â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 14743216 25241761
FBW1B B2L11 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 25332235 33961781 26186194 19150432
FBW1B TF65 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 25900982 33961781 25332235 28514442
WBP1 FBW1B â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
DLDH FBW1B â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
T22D4 FBW1B â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
SPXN3 FBW1B â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
F219A FBW1B â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
FBW1B TACC1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 25515538 25332235 33961781
FBW1B NUAK2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 24785407
FBW1B SUZ12 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 25515538 25332235 33961781
FBW1B GCP4 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 25332235
FBW1B ZN704 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 26091241 33961781 25332235 28514442
FBW1B PR15B â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 25900982 28514442 25332235 26091241
SPXN3 ARI1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
GCP5 GCP4 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26496610
GCP5 NDK7 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26496610
GCP5 GCP6 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26496610
UHRF1 FBW1A â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 28514442 23297342 33961781 26768845
ATF4 NF2L1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 20102225 16189514 11025215
SMAD3 CTNB1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 12000714 22241478 20571128 21965288 27684187
FBW1A GLI2 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 25670079 29429990
SUZ12 AEBP2 â—¼   PHYSICAL_INTERACTION ✅ 0.84 0.84 mint 24981860
FBXW2 FBW1A â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 28514442 33961781 28090088
CTNB1 LAP2 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 34079125 12047349 27684187 15123239
P53 FBW1A â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 21521785 19196987
TAZ FBW1A â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 22692215 20858893 22078877
FBW1A ZN395 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 25900982 33961781 26091241
FBW1A BHE40 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 26091241 33961781 25202122 28514442
TF65 P53 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 28205554 28628118 17434128
P53 MK14 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 10581258 20213747 17172861 15642743 21675959 21050851
FBW1B NF2L2 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 32911434 25515538 25332235
FBW1B ZN395 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 26091241 25515538 25332235 25900982 33961781
AXIN1 APC â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 7025676 19131971
NUAK1 FBW1B â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 28514442 32707033 33961781 24785407
NUAK1 FBW1A â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 28514442 32707033 33961781 24785407
UHRF1 UB2D3 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 30392931 26299963 27595565
MPIP1 SKP1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 15536641 14752276 27432908 12234927 14603323 28330616
NEDD8 ARI1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 24076655 21145461 27565346 28552575
TRIB2 FBW1A â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 24211582 23769673 25311538
P53 IKKB â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 19883646 19196987
RIPK4 FBW1B â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 29435596 32707033 26972000 33961781
FBW1B EF2K â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 22669845 25515538 25332235 23640883 25609649 32707033 23455922
EZH2 RBX1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 23238014 26496610
RBX1 FBW1A â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 32015321 29499133 20638939 25900982 33961781 30349055 12684064
P53 SNAI1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 20385133 28067227
YAP1 AXIN1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 24976009 29789528
AXIN1 PLAK â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 26496610 26871637
I10R1 FBW1A â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 32296183 22087322
FBW1A DPTOR â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 22017875 26091241 22017877 33995662 22017876 21516116
FBW1A OGT1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 25900982 19615732
FBW1A CSN6 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 21145461 26267535
P53 NRDC â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 22653443 32807901
OGT1 ZEP1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 32296183 27705803
FBW1B MYO10 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 25900982 19615732
FBW1B NRDC â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 19615732 25332235
GCP4 NDK7 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 27173435 26496610
TF65 KEAP1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 21262351 21988832
TF65 SNAI1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 19411070 25314079
SNAI1 FBW1A â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 15448698 19411070 15647282 31311807 20389281 19955572
FBW1B TFAP4 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 24500709 25515538 25332235 25900982 33961781 19615732
AXIN1 FBW1B â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 25900982 22682247 25332235
CTNB1 NFKB1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 15829968 25241761 19358846
NFKB1 FBW1B â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 22017875 25515538 25332235 33961781 12482991
EZH2 AEBP2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 29348366 26496610 27705803 28068325 33961781 24981860 26186194 27634302 24457600 31281901
FBW1A PLK4 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 25503564 20516151 26871637
FBW1B NUDC â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 25332235 25900982 33961781 19615732
RASF5 MAP1S â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 20562859 25416956 24366813
FOXN2 FBW1A â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 29396548 25609649 33961781
TACC1 FBW1A â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 32296183 25416956 33961781 26871637
FBW1A CLPX â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 19615732 33961781
FBW1A ZEP1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 26091241 25332235 25900982 33961781 19615732
FBW1A ZEP2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 26091241 25900982 33961781 19615732
FBW1B OGT1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 25900982 19615732 25332235
FBW1B ZEP1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 19615732 25332235 33961781
FBW1B CLPX â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 25900982 19615732 25332235 25515538
KHDR2 FBW1B â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 17643375
FBW1B ARI1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 25515538 25332235 27565346 33961781 19615732
FBW1B ZEP2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 25515538 25332235 33961781 19615732
STK3 STK4 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
KEAP1 RBX1 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
FBW1A KEAP1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 25900982 19615732
EZH2 SNAI1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 21685935 24903147 18519590
FBW1A TFAP4 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 24500709 26091241 25900982 33961781
YAP1 CTNB1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 24976009 21376238 23245941 27173435 33643786 29789528 27684187
FBW1A AXIN1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 22682247 10228155 24976009 29045831 25900982 29789528
P53 AXIN1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 23826318 19731416 21057547
IKBA CUL1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 14743216 29499133 22590978 17914462 10066435 11483504 10713156 11027288
CUL1 ARI1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 24076655 27565346 33961781 21145461
NEDD8 FBW1A â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 25900982 17318178 10713156
FBW1A STK3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 25900982 33961781 28514442
FBW1B REST â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 22017875 24500709 25515538 25332235 18354483 25900982 18354482
FBW1A REST â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 25453754 24760862 25515538 18354483 25299066 18354482 25197063 33038663
FBW1A GHR â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 23607312 22034227 17500058
UBP37 FBW1A â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 23027877 26299517 33961781 25347529
FBW1A NDK7 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 25900982 33961781 28514442
FBW1A ARI1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 25900982 27565346 28514442 33961781
FBW1A MAP1S â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 25900982 33961781 28514442
FBW1A NRDC â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 25900982 19615732
FBW1A EF2K â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 22669845 23640883 23455922 25900982
FBW1A STK4 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 25900982 33961781 28514442
FBW1A IKBB â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 25900982 10514424 16189514 10497169
FBW1A PLAK â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 25900982 16189514 10803460
FBW1A RASF3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 25900982 28514442 26091241 33961781
FBW1A F219A â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 25900982 28514442 26186194 33961781
FBW1A NF2L2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 34421346 32911434 31220549 26091241 25900982
BHE40 P53 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 22723347 17347673
MPIP2 MK14 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 11333986 15629715
IKKB CTNB1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 25241761 11527961
IKKB TF65 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 25241761 17962807 10521409 22689577 18519641 12842894 16046471 15489227 29084252
FBW1B MPIP2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 22017875 21807946 27880917 25515538 25332235 26496610 25900982 33961781 28675297 29150431 27432908 19615732
DLG5 CTNB1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 34079125 27684187 12657639
TRIM9 FBW1B â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 25515538 25332235 25900982 33961781 25190485
FBW1B FOXN2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 33961781 25332235 25609649
FBW1A APC â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 10228155 29045831 25900982 33961781 10074433 19615732
KEAP1 T22D4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 21988832 33961781 26186194 23382044 19615732
RBX1 NEDD8 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16503656 18247557 12481031
YAP1 FBW1A â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 21900206 28514442 20048001 24976009 32292505 33571521 29891922 32483419 29725063 33961781 29789528 30804013
ATF4 NF2L2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 32911434 16189514 23661758 26700459 11274184
IKBA SKP1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 14743216 29499133 9990852 22590978 10066435 10514433 24912152 10230406
CTNB1 SKP1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 12820959 20181957 9990852 18805092 11389839 25241761 27684187 21466614
CSN6 NEDD8 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16503656 24654937 25144743 21145461 19615732
NEDD8 P53 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 22836579 17098746 15242646 22653443 17369817 21887275 24654937 20101219 22895816 16620772 32807901 22370482 17546054
FBW1A WWTR1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 21189257 20412773 26091241 28018973 22078877 26116754 25900982 33961781 26186194
WEE1 FBW1B â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 22017875 25241761 25515538 25332235 16085715 25900982 30067982 15070733
WEE1 FBW1A â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 25900982 15070733 30067982
STK3 MAP1S â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 32707033 24366813 23455922 24255178
BORA FBW1A â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 18378770 19615732
PLK4 STIL â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 24613305 26188084
FBW1A NUDC â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 25332235 25900982 33961781 19615732
CNOT2 TB182 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 33787085 27173435 26496610 29395067
FBW1A SUN2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 26091241 25332235 30833792 25900982 33961781 19615732
FBX5 FBW1A â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 26091241 12791267 25900982 33961781 15469984
FBW1A UB2D3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 32483419 30804013 24912152 17965458
FBW1A TRIM9 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 32296183 16189514 25416956 26091241 25332235 25900982 33961781 25190485 26871637
FBW1A UBP47 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 19966869 28514442 25332235 25900982 33961781 19615732
FBW1A MPIP2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 21807946 27880917 26091241 25332235 26496610 25900982 33961781 28675297 15845771
FBW1A RASF1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 21900206 28514442 21910689 25900982 33961781
FBW1A TF65 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 16189514 25900982 33961781 9990853
RASF1 MAP1S â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 33961781 15753381 26186194 15205320 24366813
FBW1B CTNB1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 22682247 10321728 22017875 24500709 25515538 25332235 16085715 25900982 25609649 27684187 17510365
INAR1 FBW1B â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 14532120 33961781 15337770 18056411
STK4 MAP1S â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 24366813 23455922 24255178
NEDD8 RBX1 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
PLK4 STIL â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
CUL1 FBXW2 â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
AXIN1 APC â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16199882 22682247 10228155 29045831 18786926 20128690 19131971 26496610 10811618 9734785 29713058 23277359 17510365
KEAP1 NF2L2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 31541481 17822677 22558124 30122040 16790436 28533375 31257023 11439354 23727018 20027226 24844779 27212020 18757741 23722832 34526658 15572695 18417180 17462537 32911434 21262351 19706542 29423025 15985429 32206121 19920073 24011591 31169361 30793592 15475350 30765703 28638054 28186440 29792731 20463144 30778200 28534518 25628777 14585973 32159343 28939422 23382044 33391509 16785233 29255090 26536456 31941496 24704364 12145307 17015834 31262713 27091842 18387606 23645672 16449638 14517290 9887101 20484052 20599909 23066931 22448038 16888629 21383067 11909699 25582950 20486933 28416489 33393215 30473361 16006525 23986495 22331464 20421418 15601839 29033244 24512214 30383469 32605589 31695040 21988832 27621311 28617433 24130096 18981988 30126895 22245129 23857982 24322982 22302998 30692632 22215675 30576774 31891690 32057361 32854194 20864537 26078718 30465941
RBX1 UB2R1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20663873 14532120 16322693 15980415 27565346 20638939 22334663 14739463 32345600 18851830 23972993 26407237 16123592 22017877 25515538 30926793 21070969 22711876 23297342 19956254 28049764 12840033 16861890 19112177 18723677 16825193 18239684 11675391 27405755 10748083 25149538 10713156 24129577 12565873 17965458 20596027 26818844 32086376 24667174 12435635 27203182 15327770 28805820 34195792 20832730 15531760 23478441 25202122 27001857 28614300 22608923 20353940 21130766 11463388 31167929 18805092 21841822 22959436 22669845 16009132 16338364 21220517 23910095 19933270 24316736 26649820 27910872 12813041 23770852 27561354 20081843 27008177 23589337 19581926 20160477 22113614 17698585 11927591 14578910 30242702
ATF4 FBW1A â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 29892012 25416956 32296183 21988832 26091241 19053519 11238952 18052253 21516116 26871637 16219772
FBW1A SMAD4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16189514 14988407 15314162 25373906 26022109 15855639 16865698
SMAD3 SMAD4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 9111321 16189514 25514493 11927552 28443643 21988832 20211142 15084259 12732634 19768112 15467747 20142324 25609649 15922743 12917407 12419246 20564330 24382352 19139564 32296183 24157709 18729074 22442258 10092624 17283070 15350224 17591701 15761153 31591477 10995777 26555259 9892009 9311995 15588252 12167862 10878024 25910212 27703004 33990575 28115363 18055455 22310290 19135894 10531362 12794086 15231748 21297662 22045334 19917253 24584437 27107012 29892012 29997244 21532621 27845895 21597466 25502805 11114293 12543979 23788427
AXIN1 CTNB1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 10228155 27902311 30181396 24976009 20128690 12421363 17318191 19166851 18632848 19131971 16890161 26496610 20531388 23892894 32533114 18593713 21242974 22682247 19223551 9734785 17510365 16199882 23959799 12805222 29045831 22509369 29789528 34079125
CSN6 CUL1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 22474075 19141280 34237211 29103612 19295130 21145461 19615732 11337588
FBW1B CUL1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 10321728 22851693 25241761 10644755 24500709 25515538 25332235 25900982 29103612 25609649 18354482 19615732 31406304 14603323 21145461 10230406 19150432
FBW1A CUL1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 10644755 12609982 21145461 17215248 19966869 9990852 10023660 11483504 25900982 27910872 18354482 10713156 31406304 18056411 14603323 19150432 29499133 21249194 22851693 15536641 15966899 10066435 31043584 25249620 29863914 25143387 11850407 19615732 19945379 10531035 25515538 17318178 25332235 29103612 33961781 34703820
FBXW2 CUL1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 10531035 23108047 25515538 28090088 19398581 29103612 14603323 21145461 22268729
FBXW2 SKP1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 31210753 16189514 10531037 10531035 26087183 11238952 27705803 19398581 20596027 33961781 22632967 32350066 15070733 22388891
FBW1A SKP1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16189514 25416956 10644755 10228155 19933270 19061640 30254149 16275325 12609982 17283138 17215248 24469040 22388891 12820959 9990852 31467278 10023660 10918611 14706645 19159283 11483504 9660940 25900982 28614300 26474281 31210753 15536641 30728155 17463251 10514433 24912152 25632159 20596027 10074433 22632967 29863914 24811168 10531035 23607312 29997244 25332235 30267325 27705803 33961781 32350066 15070733
FBW1B SKP1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 10644755 12165731 30254149 25609649 21145461 19159283 26496610 25900982 29150431 20596027 10230406 19615732 17510365 10321728 24500709 29435596 25515538 25332235 27705803 33961781 32350066 15070733
SKP1 FBX5 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17380122 16189514 32296183 10531035 31130363 31257023 17463251 27705803 33961781
IKKB NFKB1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 25241761 16713569 11297557 11976329 10469655 11158290 22536447 12482991
NFKB1 FBW1A â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 26112410 10835356 9990852 11953428 25900982 33961781 11158290 12482991 22388891
STK4 STK3 â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 24981860
RASF3 STK3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20920251 24255178 32707033 23455922 24366813
STK3 STK4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 32707033 28628118 20562859 20920251 24981860 23386615 24255178 28205554 24366813 23455922 26344197
STK3 RASF5 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 32707033 23972470 21988832 20920251 20562859 24981860 24255178 24366813 23455922 16892067
STK3 RASF1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 17598981 32296183 32707033 28628118 20920251 20086174 28205554 14729613 17889669 33961781 17379520 24255178 26186194 24981860 18347058 23455922 24366813
SUZ12 EED â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 24981860
AEBP2 EED â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 15225548 29379173 21078963 29348366 27705803 26496610 33961781 24981860 26186194
AEBP2 SUZ12 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 15225548 29348366 27705803 33961781 35016035 26186194 24981860 27634302 24457600 31281901 20075857
FBW1A NFKB2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 14743216 18617892 14676825 15140882 16303288 25900982 11994270 22388891
NFKB2 FBW1B â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28004927 14743216 22017875 25515538 25332235 25900982
EZH2 SUZ12 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 21135039 21884980 27338022 18931660 28068325 23079660 24469040 19026780 21190999 26496610 26748827 24320048 33849069 35016035 27634302 29669287 18285464 20543829 18453536 31130994 21123648 20123894 24183680 27728805 25470042 12435631 22939629 16224021 23624935 24457600 26344197 20075857 15882624 23684459 31786184 31281901 23238014 26130719 19026781 27705803 22439931 27303043 31631027 24981860 33961781 19734898 31948940 18483221 21378168
RASF5 RASF1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16713569 11857081 20920251 32690868 24981860
UB2R2 FBW1A â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 25900982 33961781 12037680
FBW1B FBW1A â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 16189514 10644755 25900982 33961781 31406304 29150431 19615732
FBW1A IKBA â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16189514 20558726 10644755 19933270 27001857 22388891 9990852 25900982 10075690 20353940 11027288 10713156 20638939 20851351 29499133 22590978 10066435 22022389 24912152 32051583 24464578 10497169 19053519 20797629 9859996 25190485 12482991 9990853 17319651
FBW1A CTNB1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 22017875 19956254 10228155 30181396 26091241 19061640 17053147 27001857 24501426 33482471 25873176 21829575 18650423 24561623 24469040 12820959 19966869 33159601 9990852 10023660 30918250 14706645 25900982 18354482 20531388 16376880 25149538 27316454 16798748 14516475 21466614 19150432 20851351 22682247 12114015 18805092 34352208 22912335 18851830 28018973 23514615 24912152 32051583 11818547 24451375 24464578 10074433 30804013 29674637 30923315 26506240 19053519 25515538 31868589 30926793 22730322 29789528 30242702
FBW1A UB2R1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 10531035 23027877 24912152 25900982 20378537 33961781 12037680 19615732
FBW1A MPIP1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 20348946 15536641 14752276 16338364 27880917 26091241 33854235 25332235 25900982 14681206 33961781 19477924 29863914 28675297 14603323 19615732 15798217
IKKB IKBB â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 14743216 9346485 33961781 9721103 9689078
RASF1 STK4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 17598981 28628118 20920251 20562859 26578655 28205554 14729613 33961781 15109305 24255178 26186194 23386615 24981860 24366813 23455922
IKKB IKBA â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 18202307 11080499 19345327 9914500 26740240 12709429 9346485 16611882 32555320 18723677 22904686 9520446 19959994 12054687 23816567 14743216 16365431 16291755 27497262 27387502 17363905 12624112 18539148 15125833 29650758 28214532 9751059 22990857 26221961 15919917 15125834 18375836 18593939 12486103 19196987 24469399 22037600 25595906 30254148 21399639 22022389 17079871 24912152 15456896 18981174 16286467 12411322 9689078 20434986 12943667 20449947 24618592 25759022 21423167 20797629 15218148 18519641 15217903 24611898 26802121 29958295 16319058 9721103 9891086 21765415
CTNB1 PLAK â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 25241761 26496610 9535896 34079125 11712088 27684187 17510365
UBP37 FBW1B â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 25515538 25332235 26299517 33961781 25609649 19615732
FBW1B MPIP1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 22017875 16338364 27880917 25515538 25332235 25900982 14681206 33961781 25609649 27432908 28675297 29150431 14603323 15798217 28330616
FBW1B IKBA â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 14743216 16189514 10644755 12165731 10066435 18723677 24912152 27565346 33961781 26186194 12482991 10230406 17698585
FBW1B UBP47 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19966869 28514442 22017875 25515538 25332235 25900982 33961781 25609649 19615732
STK4 RASF3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20920251 23455922 24255178 24366813
AEBP2 EED â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
EZH2 EED â—¼   PHYSICAL_INTERACTION ✅ 0.91 0.91 mint 24981860
NEDD8 SKP1 â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
NEDD8 SKP1 â—¼   PROTEIN_INTERACTION 0.92 0.92 HIPPIE 16503656 21145461 18247557 27705803
FBXW2 SKP1 â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
AEBP2 EZH2 â—¼   PHYSICAL_INTERACTION 934.0 0.93 STRING 36370105
FBW1B PDCD4 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 22669845 24500709 25515538 25332235 25900982 33961781 19615732
IKBA NFKB2 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 28514442 14743216 32912968 26496610 33961781 26186194
NFKB2 IKBB â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 28514442 14743216 33961781 26186194
WBP1 YAP1 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 25283809 9202023 7644498 11604498
SKP1 CUL1 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 7304783 18818696
SUZ12 EZH2 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 24981860
IKBA IKBB â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 22081069 14743216 28514442 33961781 26186194
IKKB KEAP1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 24322982 19818716 27387502 30126895 25926686 30500824 24127568 20600852
LAP2 SMAD3 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 18729074 17591701 12650946 18003620
NEDD8 CUL1 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 6541102 18274552
UB2R1 CUL1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 25425648 12565873 16123592 18851830 27001857 29564676 11032804 11245432 19945379
NFKB1 IKBB â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 14743216 27609421 35140242 33961781 26186194
PDCD4 FBW1A â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 22669845 28514442 26091241 17053147 22586265 25900982 33961781 18296647 23056346
P53 IKBA â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 16189514 32912968 16713569 11799106 15969767
APC PLAK â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 11707392 25241761 7651399 8074697 26496610 9298899 11348595 11136974 20936779
RBX1 SKP1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 16189514 12504025 12840033 12481031 26540345 11245432 29507117 10531037 16357137 30349055 15452136 12813041 23770852 29499133 12628165 11961546 29863914 33692209 27705803 33504946 12684064
NEDD8 CUL1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 16503656 18723677 16620772 23201271 21145461 22474075 18247557 24076655 10772955 17438373 19245792 24654937 21102408 10713156 11027288 21765416 10597293 22405651 12565873 18805092 18826954 18274552 19713960 16177058 22959436 24949976 32726803 19617556 17206147 10318914 17318178 21119685 18264111 18627766 23267066
NFKB1 TF65 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 20547752 8255759 27609421 29439025 16740634 21988832 24634218 14645533 11970949 35140242 15799966 25609649 15660126 21544861 29084252 14743216 8246997 34100597 22139845 17962807 9722548 2050119 22808155 20154269 21270162 17982102 24175631 25355951 23687337 11976329 15657065 8428580 20237821 12414801 10498867 22261743 16204234 16105840 14690596 11880271 33060567 8798655 16319923 21483817
NFKB1 IKBA â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 20558726 7891711 27609421 29439025 21988832 7739549 16210649 8631829 35140242 25609649 17003112 9566883 14743216 26496610 8887676 22536447 32912968 9572494 9865693 33572115 20237821 9738011 11313474 20980497 33961781 11020244 26186194
NFKB1 NFKB2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 14743216 27609421 21988832 17962807 15169888 35140242 25609649 15660126
EED SUZ12 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 29379173 27338022 19026780 26496610 35016035 27634302 15385962 15225548 18285464 20543829 12435631 31786184 24457600 31281901 20075857 19026781 21078963 27705803 22439931 28320739 33961781 24981860 23280602 18483221
EED EZH2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 21135039 9584197 9742080 31948940 29379173 27338022 18931660 28068325 33754075 11158321 9584199 32296183 22897849 17937919 19026780 21190999 26496610 24320048 33849069 27634302 15385962 16314526 29669287 15225548 18285464 10581039 21123648 12435631 31786184 23624935 24457600 20075857 15882624 19026781 21078963 22094255 22439931 28320739 27705803 31527584 24981860 33961781 23280602 26344197
TF65 NFKB2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 14743216 27609421 17962807 16009713 8413211 16940413 29084252
RASF5 STK4 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 11864565 16713569 20920251 20562859 17517604 24981860 15109305 24255178 24366813 23455922 16892067
IKBB TF65 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 14685242 14743216 16189514 22081069 28514442 27609421 21988832 33961781 8887627 8816457 26186194 12672800 10498867
AEBP2 SUZ12 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
APC CTNB1 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 19576224 22056988 25241761 27902311 15327769 9707618 8638126 17318191 11251183 15327768 27684187 10545404 15355978 8259519 16510874 26496610 32533114 11533658 22682247 7890674 11166179 11972058 11707392 23840886 11712088 15525529 34079125 16212417 33858476 17510365 21664290 9482734 29045831 33961781 12628243 9286858 12000790 10773885
RBX1 CUL1 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 16189514 12504025 20832730 15448697 10230407 19933270 12840033 12904573 18723677 12504026 12481031 17452440 12609982 26540345 27697867 22474075 11245432 22767593 28152074 22822056 19245792 12706828 11861641 20399188 10748083 11956208 11483504 27910872 16759355 30349055 10713156 11027288 21765416 20638939 22405651 23770852 19942853 10648623 12565873 18826954 18805092 32145688 21169563 27591266 22660580 11961546 32313199 15361859 19250909 29863914 24949976 10230406 32726803 30653357 32015321 33692209 16123592 34237211 29958295 29103612 33961781 33504946 12684064 26725323 26344197
TF65 IKBA â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 14685242 28514442 27609421 29439025 21988832 7739549 24634218 23850221 11533489 23185316 15799966 30628021 17003112 16951195 8887633 25520503 20065107 9566883 16683270 22081069 14743216 8246997 17612295 11287411 20551178 23563313 29084252 8657102 9694722 11231305 9057089 26496610 17301240 21217772 33754058 9751059 29734393 20876301 30213788 24457201 32912968 12419806 25609694 26476452 22022389 9572494 15657065 9865693 10066434 9738011 10085161 8978697 24248593 10498867 27923823 30542119 11313474 19219072 16105840 14690596 25759022 20797629 33060567 20980497 33961781 11020244 8887627 8139561 26186194 26463447 9990853 33478005 7878004 7628694
EED SUZ12 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
EZH2 SUZ12 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
APC AXIN1 â—¼   PHYSICAL_INTERACTION 26.0 1.0 ACSN 10421629 10581160 11487578 11955436 11967263 12051714 12554650 15001769 15327768 16039586 16288291 16940750 17143292 17318175 17936032 19619488 19751508 20006983 20705860 22270359 23343194 24023259 25730849 7542250 8638126 8666229
APC NEDD8 â—¼   PHYSICAL_INTERACTION 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
APC RBX1 â—¼   PHYSICAL_INTERACTION 76.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 14536078 15001769 15071497 15147722 15340381 15459660 15489953 15688063 1570337 15703371 16039586 16469695 16697054 16713974 16940750 17053147 17143292 17652783 17884153 17928543 17936032 18196958 18636226 18787170 18805092 18931676 19143635 19150432 19250909 19258535 19270156 19352404 19366350 19411070 19557001 19576224 19597341 19619488 19622404 19686080 19751508 19797085 19809470 19836308 19847258 19849719 20006983 20211143 20558317 20705860 20832730 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26159692 26885856 7542250 7641885 8666229 9694792
APC CUL1 â—¼   PHYSICAL_INTERACTION 76.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 14536078 15001769 15071497 15147722 15340381 15459660 15489953 15688063 1570337 15703371 16039586 16469695 16697054 16713974 16940750 17053147 17143292 17652783 17884153 17928543 17936032 18196958 18636226 18787170 18805092 18931676 19143635 19150432 19250909 19258535 19270156 19352404 19366350 19411070 19557001 19576224 19597341 19619488 19622404 19686080 19751508 19797085 19809470 19836308 19847258 19849719 20006983 20211143 20558317 20705860 20832730 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26159692 26885856 7542250 7641885 8666229 9694792
APC AXIN1 â—¼   PROTEIN_INTERACTION 26.0 1.0 ACSN 10421629 10581160 11487578 11955436 11967263 12051714 12554650 15001769 15327768 16039586 16288291 16940750 17143292 17318175 17936032 19619488 19751508 20006983 20705860 22270359 23343194 24023259 25730849 7542250 8638126 8666229
APC RBX1 â—¼   SHARES_COMPLEX 76.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 14536078 15001769 15071497 15147722 15340381 15459660 15489953 15688063 1570337 15703371 16039586 16469695 16697054 16713974 16940750 17053147 17143292 17652783 17884153 17928543 17936032 18196958 18636226 18787170 18805092 18931676 19143635 19150432 19250909 19258535 19270156 19352404 19366350 19411070 19557001 19576224 19597341 19619488 19622404 19686080 19751508 19797085 19809470 19836308 19847258 19849719 20006983 20211143 20558317 20705860 20832730 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26159692 26885856 7542250 7641885 8666229 9694792
APC NEDD8 â—¼   SHARES_COMPLEX 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
APC CUL1 â—¼   SHARES_COMPLEX 76.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 14536078 15001769 15071497 15147722 15340381 15459660 15489953 15688063 1570337 15703371 16039586 16469695 16697054 16713974 16940750 17053147 17143292 17652783 17884153 17928543 17936032 18196958 18636226 18787170 18805092 18931676 19143635 19150432 19250909 19258535 19270156 19352404 19366350 19411070 19557001 19576224 19597341 19619488 19622404 19686080 19751508 19797085 19809470 19836308 19847258 19849719 20006983 20211143 20558317 20705860 20832730 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26159692 26885856 7542250 7641885 8666229 9694792
APC RBX1 â—¼   ENZYMATIC_REACTION ✅ 76.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 14536078 15001769 15071497 15147722 15340381 15459660 15489953 15688063 1570337 15703371 16039586 16469695 16697054 16713974 16940750 17053147 17143292 17652783 17884153 17928543 17936032 18196958 18636226 18787170 18805092 18931676 19143635 19150432 19250909 19258535 19270156 19352404 19366350 19411070 19557001 19576224 19597341 19619488 19622404 19686080 19751508 19797085 19809470 19836308 19847258 19849719 20006983 20211143 20558317 20705860 20832730 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26159692 26885856 7542250 7641885 8666229 9694792
APC NEDD8 â—¼   ENZYMATIC_REACTION ✅ 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
APC CUL1 â—¼   ENZYMATIC_REACTION ✅ 76.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 14536078 15001769 15071497 15147722 15340381 15459660 15489953 15688063 1570337 15703371 16039586 16469695 16697054 16713974 16940750 17053147 17143292 17652783 17884153 17928543 17936032 18196958 18636226 18787170 18805092 18931676 19143635 19150432 19250909 19258535 19270156 19352404 19366350 19411070 19557001 19576224 19597341 19619488 19622404 19686080 19751508 19797085 19809470 19836308 19847258 19849719 20006983 20211143 20558317 20705860 20832730 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26159692 26885856 7542250 7641885 8666229 9694792
AXIN1 APC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 16199882 20128690 19131971 11297546 9554852 22682247 10228155 26496610 23277359 10811618 9734785
RBX1 KEAP1 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 11900249 12648680 12820959 15340381 15459660 15688063 15703371 16697054 17312394 17884153 18931676 19560419 19622404 19686080 19809470 19818716 19847258 23030059 23850759
RBX1 KEAP1 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 11900249 12648680 12820959 15340381 15459660 15688063 15703371 16697054 17312394 17884153 18931676 19560419 19622404 19686080 19809470 19818716 19847258 23030059 23850759
CUL1 RBX1 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
GLI2 RBX1 â—¼   PHYSICAL_INTERACTION 18.0 1.0 Reactome 15198976 19852954 20360384 21878643 19684112 9874371 16651542 15115751 19955409 20154143 20487519 20014402 20956384 19818708 16740475 24072710 14528312 23955340
NFKB1 RBX1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 9990852 10514433 9859996 9990853 7628694
RBX1 SKP1 â—¼   PHYSICAL_INTERACTION 24.0 1.0 ACSN 11900249 12648680 12820959 14536078 15071497 15147722 15340381 15459660 15489953 15688063 15703371 16697054 17053147 17884153 18636226 18787170 18931676 19150432 19270156 19622404 19686080 19797085 19809470 19847258
RBX1 NEDD8 â—¼   PHYSICAL_INTERACTION 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
RBX1 CUL1 â—¼   PHYSICAL_INTERACTION 76.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 14536078 15001769 15071497 15147722 15340381 15459660 15489953 15688063 1570337 15703371 16039586 16469695 16697054 16713974 16940750 17053147 17143292 17652783 17884153 17928543 17936032 18196958 18636226 18787170 18805092 18931676 19143635 19150432 19250909 19258535 19270156 19352404 19366350 19411070 19557001 19576224 19597341 19619488 19622404 19686080 19751508 19797085 19809470 19836308 19847258 19849719 20006983 20211143 20558317 20705860 20832730 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26159692 26885856 7542250 7641885 8666229 9694792
RBX1 CUL1 â—¼   SHARES_COMPLEX 76.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 14536078 15001769 15071497 15147722 15340381 15459660 15489953 15688063 1570337 15703371 16039586 16469695 16697054 16713974 16940750 17053147 17143292 17652783 17884153 17928543 17936032 18196958 18636226 18787170 18805092 18931676 19143635 19150432 19250909 19258535 19270156 19352404 19366350 19411070 19557001 19576224 19597341 19619488 19622404 19686080 19751508 19797085 19809470 19836308 19847258 19849719 20006983 20211143 20558317 20705860 20832730 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26159692 26885856 7542250 7641885 8666229 9694792
RBX1 SKP1 â—¼   SHARES_COMPLEX 24.0 1.0 ACSN 11900249 12648680 12820959 14536078 15071497 15147722 15340381 15459660 15489953 15688063 15703371 16697054 17053147 17884153 18636226 18787170 18931676 19150432 19270156 19622404 19686080 19797085 19809470 19847258
RBX1 NEDD8 â—¼   SHARES_COMPLEX 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
RBX1 NEDD8 â—¼   ENZYMATIC_REACTION ✅ 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
RBX1 CUL1 â—¼   ENZYMATIC_REACTION ✅ 76.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 14536078 15001769 15071497 15147722 15340381 15459660 15489953 15688063 1570337 15703371 16039586 16469695 16697054 16713974 16940750 17053147 17143292 17652783 17884153 17928543 17936032 18196958 18636226 18787170 18805092 18931676 19143635 19150432 19250909 19258535 19270156 19352404 19366350 19411070 19557001 19576224 19597341 19619488 19622404 19686080 19751508 19797085 19809470 19836308 19847258 19849719 20006983 20211143 20558317 20705860 20832730 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26159692 26885856 7542250 7641885 8666229 9694792
RBX1 WEE1 â—¼   ENZYMATIC_REACTION ✅ 17.0 1.0 ACSN 11900249 12648680 12820959 15071497 15147722 15340381 15459660 15688063 15703371 16697054 17884153 18931676 19270156 19622404 19686080 19809470 19847258
RBX1 PDCD4 â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 ACSN 11900249 12648680 12820959 15071497 15340381 15459660 15688063 15703371 16697054 17053147 17884153 18931676 19270156 19622404 19686080 19797085 19809470 19847258
RBX1 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11359933
RBX1 CUL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 154.0 1.0 Omnipath 17053147 12684064 20638939 11967263 19797085 19258535 26540345 18826954 15071497 15448697 21765416 25730849 10230406 23343194 21169563 22270359 19250909 23732914 11359933 12051714 20006983 15361859 10748083 19352404 22682247 18787170 12504025 18636226 16469695 15459660 20211143 10535940 15001769 26725323 19411070 11861641 26159692 16697054 1570337 19751508 22822056 11348595 7542250 7641885 19849719 16759355 12820959 17452440 19622404 15703371 10648623 19245792 23331499 9694792 19150432 23180781 19597341 16189514 22474075 18988627 22767593 17143292 24949976 10713156 23770852 22405651 19942853 18196958 20399188 16713974 26192618 11027288 17884153 19933270 22730322 21411632 11961546 17936032 19809470 15147722 19270156 19576224 11483504 20976471 12504026 24023259 12840033 15340381 12904573 20558317 11900249 14536078 19686080 12565873 18805092 15489953 19557001 26885856 17652783 12481031 20843316 11955436 21071413 16039586 11956208 20705860 8666229 17928543 10023660 19836308 16940750 12706828 19143635 15688063 10671552 16123592 19366350 19847258 12417738 11245432 20832730 12648680 12609982 19619488 10230407 18931676
SMAD3 SNAI1 â—¼   PHYSICAL_INTERACTION 20.0 1.0 ACSN 11074002 11279127 11792802 12702545 12809600 15265520 16179589 16713975 17018611 17563753 18768831 19597490 21041997 21042762 21577210 21614932 22331441 22514743 8515656 9389648
SMAD4 SNAI1 â—¼   PHYSICAL_INTERACTION 41.0 1.0 ACSN 11074002 11279127 11792802 12490555 12702545 12809600 14623871 15265520 16179589 16510505 16617148 16713975 16831886 17018611 17093497 17403902 17490644 17550342 17563753 17671186 18297062 18768831 18832382 19208835 19412634 19597490 20731704 21041997 21042762 21199805 21317430 21577210 21614932 21883379 22006115 22331441 22406545 22514743 22945800 8515656 9389648
SNAI1 EZH2 â—¼   PHYSICAL_INTERACTION 8.0 1.0 ACSN 15465827 17018611 17563753 21234400 21577210 21685935 22514743 22796940
SMAD3 SNAI1 â—¼   SHARES_COMPLEX 20.0 1.0 ACSN 11074002 11279127 11792802 12702545 12809600 15265520 16179589 16713975 17018611 17563753 18768831 19597490 21041997 21042762 21577210 21614932 22331441 22514743 8515656 9389648
SMAD4 SNAI1 â—¼   SHARES_COMPLEX 41.0 1.0 ACSN 11074002 11279127 11792802 12490555 12702545 12809600 14623871 15265520 16179589 16510505 16617148 16713975 16831886 17018611 17093497 17403902 17490644 17550342 17563753 17671186 18297062 18768831 18832382 19208835 19412634 19597490 20731704 21041997 21042762 21199805 21317430 21577210 21614932 21883379 22006115 22331441 22406545 22514743 22945800 8515656 9389648
SNAI1 EZH2 â—¼   SHARES_COMPLEX 8.0 1.0 ACSN 15465827 17018611 17563753 21234400 21577210 21685935 22514743 22796940
SMAD4 SNAI1 â—¼   UP_REGULATES ✅ + 41.0 1.0 ACSN 11074002 11279127 11792802 12490555 12702545 12809600 14623871 15265520 16179589 16510505 16617148 16713975 16831886 17018611 17093497 17403902 17490644 17550342 17563753 17671186 18297062 18768831 18832382 19208835 19412634 19597490 20731704 21041997 21042762 21199805 21317430 21577210 21614932 21883379 22006115 22331441 22406545 22514743 22945800 8515656 9389648
SMAD3 SNAI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 20731704 9389648 18832382 16831886 17563753 22406545 11074002 21317430 16617148 17671186
YAP1 WWTR1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 ACSN 12807903 18280240 18617895 21666501 23708000 25502501 26711338 7782338
YAP1 WWTR1 â—¼   PROTEIN_INTERACTION 8.0 1.0 ACSN 12807903 18280240 18617895 21666501 23708000 25502501 26711338 7782338
SMAD3 SMAD4 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
SMAD4 SMAD3 â—¼   PHYSICAL_INTERACTION 72.0 1.0 ACSN 10454538 10925299 10964912 11007770 11013125 11013220 11074002 11114293 11224571 11279127 11283613 11283614 11376132 11399519 11792802 11875494 12193690 12545156 12702545 12809600 14976548 15001984 15095404 15155580 15265520 15644117 16127449 16179589 16713975 16831886 17018611 17055429 17260466 17550342 17563753 17689680 17705132 18353785 18768831 18832382 19208835 19597490 19815509 19901969 20027199 20713526 20731704 21041997 21042762 21098712 21252118 21317430 21577210 21614932 2191300 22331441 22514743 22652804 23140366 23338822 23390297 23784029 23869868 25374926 6357187 8515656 8871614 8893010 9312026 9389648 9618481 9670020
SMAD4 SMAD3 â—¼   PROTEIN_INTERACTION 72.0 1.0 ACSN 10454538 10925299 10964912 11007770 11013125 11013220 11074002 11114293 11224571 11279127 11283613 11283614 11376132 11399519 11792802 11875494 12193690 12545156 12702545 12809600 14976548 15001984 15095404 15155580 15265520 15644117 16127449 16179589 16713975 16831886 17018611 17055429 17260466 17550342 17563753 17689680 17705132 18353785 18768831 18832382 19208835 19597490 19815509 19901969 20027199 20713526 20731704 21041997 21042762 21098712 21252118 21317430 21577210 21614932 2191300 22331441 22514743 22652804 23140366 23338822 23390297 23784029 23869868 25374926 6357187 8515656 8871614 8893010 9312026 9389648 9618481 9670020
SMAD4 GLI2 â—¼   ENZYMATIC_REACTION ✅ 20.0 1.0 ACSN 11013125 11074002 11279127 11376132 11792802 12702545 12809600 15265520 16179589 16713975 18768831 21042762 21098712 21614932 22331441 22652804 23784029 25374926 8515656 9389648
SMAD4 SMAD3 â—¼   LOCALISATION ✅ 72.0 1.0 ACSN 10454538 10925299 10964912 11007770 11013125 11013220 11074002 11114293 11224571 11279127 11283613 11283614 11376132 11399519 11792802 11875494 12193690 12545156 12702545 12809600 14976548 15001984 15095404 15155580 15265520 15644117 16127449 16179589 16713975 16831886 17018611 17055429 17260466 17550342 17563753 17689680 17705132 18353785 18768831 18832382 19208835 19597490 19815509 19901969 20027199 20713526 20731704 21041997 21042762 21098712 21252118 21317430 21577210 21614932 2191300 22331441 22514743 22652804 23140366 23338822 23390297 23784029 23869868 25374926 6357187 8515656 8871614 8893010 9312026 9389648 9618481 9670020
SMAD3 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 104.0 1.0 Omnipath 25609649 9843571 15084259 20211142 21532621 24584437 18729074 23788427 12419246 18923419 9892009 19768112 10531362 15231748 9679060 12167862 21988832 12150994 23331499 12543979 18568018 21071413 19135894 15467747 25502805 9732876 11927552 16189514 12917407 25514493 15350224 10995777 18988627 10092624 12732634 25910212 10878024 9111321 20564330 27107012 9311995 12957874 20142324 11114293 32296183 15588252 15761153 24157709 26555259 29892012 17469184 22442258 16714330 21597466 15922743 22045334 17591701 24382352 22310290 19139564 19917253 29997244 31515488 28115363 10942775 21297662 17283070 12794086
SMAD3 GLI2 â—¼   ENZYMATIC_REACTION ✅ 20.0 1.0 ACSN 11013125 11074002 11279127 11376132 11792802 12702545 12809600 15265520 16179589 16713975 18768831 21042762 21098712 21614932 22331441 22652804 23784029 25374926 8515656 9389648
CUL1 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 11359933
AXIN1 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11438668 23331499 18988627
NFKB1 CUL1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 9990852 10514433 9859996 9990853 7628694
NFKB2 CUL1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 9346238 15340381 16303288 8706131
CUL1 SKP1 â—¼   PHYSICAL_INTERACTION 26.0 1.0 ACSN 11516665 11900249 12648680 12820959 14536078 15071497 15147722 15340381 15459660 15489953 15668399 15688063 15703371 16697054 17053147 17884153 18636226 18787170 18931676 19150432 19270156 19622404 19686080 19797085 19809470 19847258
CUL1 NEDD8 â—¼   PHYSICAL_INTERACTION 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
CUL1 SKP1 â—¼   PROTEIN_INTERACTION 1.0 1.0 HIPPIE 14685242 16189514 17290223 20832730 12504025 12904573 10230407 19933270 23324393 12504026 9636170 26540345 12609982 27697867 26753747 21145461 22474075 28007894 18818696 9736735 9990852 22767593 28152074 10023660 29070679 9827542 23951410 16357137 16759355 10713156 15452136 19270694 11027288 26474281 23770852 10648623 29499133 21249194 34499862 12628165 15966899 21169563 22660580 11961546 9430629 32313199 29863914 10230406 30653357 19945379 9663463 21778237 34237211 18094045 26976582 27705803 32249768 29103612 33961781 12684064 26725323
CUL1 NEDD8 â—¼   SHARES_COMPLEX 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
CUL1 SKP1 â—¼   SHARES_COMPLEX 26.0 1.0 ACSN 11516665 11900249 12648680 12820959 14536078 15071497 15147722 15340381 15459660 15489953 15668399 15688063 15703371 16697054 17053147 17884153 18636226 18787170 18931676 19150432 19270156 19622404 19686080 19797085 19809470 19847258
CUL1 PDCD4 â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 ACSN 11900249 12648680 12820959 15071497 15340381 15459660 15688063 15703371 16697054 17053147 17884153 18931676 19270156 19622404 19686080 19797085 19809470 19847258
CUL1 NEDD8 â—¼   ENZYMATIC_REACTION ✅ 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
CUL1 WEE1 â—¼   ENZYMATIC_REACTION ✅ 17.0 1.0 ACSN 11900249 12648680 12820959 15071497 15147722 15340381 15459660 15688063 15703371 16697054 17884153 18931676 19270156 19622404 19686080 19809470 19847258
SKP1 CUL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 66.0 1.0 Omnipath 9663463 19945379 12684064 19270694 16759355 23951410 10648623 11961546 26540345 26976582 26474281 17290223 9736735 21169563 14685242 16357137 21145461 29070679 15452136 15966899 12628165 21778237 22474075 16189514 22767593 11359933 9430629 10713156 10023660 10228155 12504026 18818696 9827542 12504025 18094045 10066435 23324393 23770852 9990852 12417738 27705803 9636170 21249194 12904573 34499862 11027288 26725323 20832730 19933270 12609982 10230407
CUL1 GLI2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 17053147 15340381 16611981 18813803 16651270 12820959 19797085 15071497 15688063 16371461
NFKB1 SKP1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 9990852 10514433 9859996 9990853 7628694
SKP1 NFKB2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 9346238 15340381 16303288 8706131
SKP1 WEE1 â—¼   ENZYMATIC_REACTION ✅ 17.0 1.0 ACSN 11900249 12648680 12820959 15071497 15147722 15340381 15459660 15688063 15703371 16697054 17884153 18931676 19270156 19622404 19686080 19809470 19847258
SKP1 PDCD4 â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 ACSN 11900249 12648680 12820959 15071497 15340381 15459660 15688063 15703371 16697054 17053147 17884153 18931676 19270156 19622404 19686080 19797085 19809470 19847258
SKP1 GLI2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 17053147 15340381 16611981 18813803 16651270 12820959 19797085 15071497 15688063 16371461
EED EZH2 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105