Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
SPRED1 PARVG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CTNNB1 BTRC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15473860 10882123
CREB1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 10775268
CREB1 TCF3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20864035
SPRED1 CTNNB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
GLI1 CTNNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19329935 19930158
E2F1 CTNNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 14706452 18794899
E2F1 HMGA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22389255
E2F1 TOP2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11313881
E2F1 HSPA5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18840615
EEF1G TRIB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
IMMT UBQLN4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
PRMT6 TRIB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
SPRED1 TRIB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TRIB2 UBQLN4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
RBM14 SAFB2 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
TRIB2 UB2E1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
TRIB1 UB2E1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
TRIB2 CH60 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
TRIB2 KCD21 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
TRIB2 SKT â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
DET1 STK40 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
TRIB2 GSTA4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
TRIB2 ISCA1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
TRIB1 ISCA1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
TRIB2 POTEF â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
TFAP4 TRIB2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
TRIB2 TRIB1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
DET1 UB2E1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 17452440
RBM14 PARP1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 11443112 16713569
BCLAF1 THRAP3 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
TRIB2 FBW1A â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 25311538 23769673 24211582
TRIB1 DET1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33961781 28514442 32707033
TRIB2 DET1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33961781 28514442 32707033
STK40 RFWD2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33961781 26186194 28514442 32707033 28089446
TRIB2 STK40 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33961781 28514442 32707033
TRIB1 STK40 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33961781 25852190 26186194 28514442 32707033
PARP1 TOP2A â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 20085707 34079125
TRIB2 RFWD2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 33961781 25311538 34646775 28514442 32707033
DET1 RFWD2 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
RFWD2 TRIB1 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
RFWD2 STK40 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
STK40 TRIB1 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
CUL1 E2F1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 11245432 10559858
FBW1A TFAP4 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 24500709 25900982 28514442 26091241
BTRC CTNNB1 â—¼   UBIQUITINATION ✅ - 0.88 0.88 Signor 10228155
PARP1 E2F1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 20133863 14627987
FBW1A CUL1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 14603323 25900982 25332235 22851693 11850407 15536641 29103612 18056411 25143387 18354482 31406304 21249194 25249620 10644755 31043584 19966869 17215248 17318178 10713156 10023660 15966899 19615732 11483504 10066435 10531035 34703820 28514442 29499133 12609982 19945379 21145461 25515538 27910872 19150432 9990852 29863914
CEBPA E2F1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 12869508 11340171 12702500
E2F1 HSPA5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18840615
NR1I2 TRIB2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19129222
RPS6KB1 RPTOR â—¼   PHYSICAL_INTERACTION 907.0 0.9 STRING 36370105
CEBPA TRIB1 â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
CTNNB1 TCF4 â—¼   PHYSICAL_INTERACTION 929.0 0.92 STRING 36370105
TRIM21 UBE2E1 â—¼   PHYSICAL_INTERACTION 929.0 0.92 STRING 36370105
CUL1 BTRC â—¼   PHYSICAL_INTERACTION ✅ 0.93 0.93 mint 17318178 5219675
CTNNB1 BTRC â—¼   PHYSICAL_INTERACTION ✅ 0.93 0.93 mint 5218183 16376880
TCF12 TCF4 â—¼   PHYSICAL_INTERACTION 934.0 0.93 STRING 36370105
TCF4 CTNNB1 â—¼   PHYSICAL_INTERACTION ✅ 0.94 0.94 mint 5219694 17318191
BTRC CUL1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
BTRC CTNNB1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CUL1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 10228155 10713156 10023660
HLCS ACACA â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 Reactome 9630604 14766011 10677481 7732023 16134170 20153287 22123817
BTRC CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 68.0 1.0 Omnipath 23514615 17053147 22912335 17145710 27001857 20531388 18851830 12820959 24451375 18805092 25900982 11818547 16798748 19061640 19956254 23331499 24912152 19150432 22017875 24501426 28018973 16376880 21466614 27316454 19053519 26506240 14516475 25149538 10023660 22682247 10228155 9461217 24464578 18354482 26091241 10074433 12114015 9990852 14706645 18650423 25873176 19966869 25515538 20851351 22730322 24469040
CTNNB1 TCF4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12086873 11943708 13679048 15806138
CTNNB1 TCF3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12107263 15327769 23331499 9488439 11136974
CTNNB1 TCF4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 47.0 1.0 Omnipath 24532795 11713475 18281465 25402006 16724116 12799378 12944908 12727872 23331499 15060161 17412698 22080605 21743491 17875931 12657632 17983804 20126258 17318191 24798214 24876153 29361949 17909039 23449499 22699938 18595660 9308964 16007074 15331612 11713476 15665104 17072306 15525529 17962194
PARP1 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 14627987 20133863
RPS6KB1 GLI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 26512695 29163356 28735864 25476449 22439934 24661902 23880852 25134527
RPTOR RPS6KB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16183647 12087098 12604610 9465032 28249155 12150926
PARP1 PARP1 â—¼   KO_DOWN_REGULATES ✅ - -7.28 7.27 PKG 28854368