Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
CCT2 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
CCT3 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
CCT3 STAT3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 24756126 1001844
YWHAZ CCT4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
CCT8 CCT6A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
CCT6A YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
YWHAZ CCT7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
CCT8 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
SOX2 CDKN1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22469032 22855803
COPS6 STK40 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
COPS6 TRIB3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
TRIB3 COPS6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16169070
YWHAZ DDB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
FOXO1 FASN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16997836 24478438
FOXO1 PNPLA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21743036 19297333
FOXO1 SIRT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21149440 23430617
FOXO1 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 25510553 19049975
FOS MDM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10348347 12173040
ETS2 MDM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12750288
MDM2 MDM4 â—¼   COLOCALIZATION 2.0 0.8 intact 17159902 5219425
YWHAB MDM4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16511560 5218386
MDM4 TP53 â—¼   COLOCALIZATION 2.0 0.8 intact 19521340 7290688
TP53 SFN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7711923 20206173
HSPA8 SIRT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 19229036 23349863
JUN SIRT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22610349 23161884
CEBPA STAT3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24429361
STAT3 SOX2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20132009 18447642
STAT3 CSN2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9195960 7519723
STAT3 PTPN1 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 intact 15821101 6673264
STAT3 JUNB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11533249
TCP1 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
FOS TP53 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11350971 10984493
TP53 JUN â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11350971 10984493
ETS2 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8649821 10510472
TP53 NFKBIA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10698490 12700242
RCHY1 TP53 â—¼   COLOCALIZATION 2.0 0.8 intact 5220017 17568776
HSPA8 NFKBIA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
PTPN1 NFKBIA â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 intact 8940099 6673106
JUN JUND â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8922393 2504580
JUN ETS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22354960
HSPA8 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
MVP YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
YWHAZ FASN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
CUL4A RFWD2 â—¼   PHYSICAL_INTERACTION 801.0 0.8 STRING 36370105
HSPA2 HSPA8 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
NFKBIA SFN â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
MDM2 CUL4B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28225217 22032989
CUL4B WDR5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31155351 17041588
RFWD2 PARP4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 25117710 33961781
CUL4A WDR5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31155351 17041588
WDR5 TCPA â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33022573 27705803
WDR5 TCPG â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33022573 27705803
WDR5 TCPH â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33022573 27705803
NFIL3 STK40 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
NFIL3 RFWD2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
RFWD2 CSN2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19295130 12466024
DET1 CSN2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
RFWD2 JPH1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
JUN P53 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31182485 25609649
FOS TRIB1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 35140242 25609649
2ABD RFWD2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
ZN263 RFWD2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
ATF6A RFWD2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33961781 25609649
KHDR2 RFWD2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
TINAG RFWD2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
TSKS RFWD2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
RFWD2 SPOP â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
RFWD2 SPCS â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
RFWD2 AGGF1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
RFWD2 CSN8 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19295130 12466024
RFWD2 TAXB1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
RFWD2 TCPA â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 16497536 33961781
RFWD2 F120B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
RFWD2 TCPW â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
RFWD2 PP2AA â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
RFWD2 CE164 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
TINAG STK40 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
ATF6A STK40 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33961781 25609649
DET1 STK40 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
JUNB DET1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
DET1 CSN6 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
TINAG PP2AA â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
TRIB2 TRIB1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
FOS STK40 â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
COPS8 RBX1 â—¼   PHYSICAL_INTERACTION 828.0 0.82 STRING 36370105
DDA1 RFWD2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 25117710 19295130 31155351 33961781
WDR5 DDB1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 31155351 33022573 17041588
MDM4 1433S â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 16511560 16511572
P53 RBX1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22653443 30349055 23443559
RFWD2 RBX1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 19295130 14739464 32041890
WDR5 SOX2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 30089852 35140242 29383478
2ABD JUN â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 19156129
JUN JUND â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 25609649
FOS DET1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 35140242 33961781 26186194
FOSL2 RFWD2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194 26496610
ZN397 RFWD2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
RFWD2 TCPZ â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 16497536 33961781
RFWD2 TCPH â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 16497536 33961781
RFWD2 MVP â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 15994960 33961781 25117710
RFWD2 TCPB â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 16497536 33961781
RFWD2 TCPG â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 16497536 33961781
ZN397 STK40 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
JUNB STK40 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 28089446 33961781
ETV5 STK40 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
FOSL2 STK40 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 28089446 33961781 26186194
ETV1 STK40 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
FOSL2 DET1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
FOSL2 TRIB1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
ETV1 DET1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
ETV5 DET1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
P53 TCPA â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22653443 25144556 35140242 23443559
P53 TCPB â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 23443559 22653443 31152661 35140242 25144556
P53 TCPZ â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22653443 25144556 35140242 23443559
P53 TCPH â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 23443559 22653443 31152661 35140242 25144556
P53 TCPG â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22653443 25144556 35140242 23443559
ZN397 ZN263 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
COPS2 RBX1 â—¼   PHYSICAL_INTERACTION 834.0 0.83 STRING 36370105
CDKN1B CUL4A â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
ETV4 RFWD2 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
CSN2 JUN â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 16045761 25609649 10903862
CSN6 JUN â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 25609649 26237449 10903862
COPS6 DDB1 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
DET1 CUL4B â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 28514442 33961781 16949367 31973889
CUL4B RFWD2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 31973889 19295130 17041588
CUL4A DDA1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 31973889 17452440 16964240 21145461 19295130 16949367
DDB1 CSN6 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 22767593 16964240 21145461 19295130 16949367
TRIB3 STK40 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 28514442 32707033 33961781 26186194
STK40 RFWD2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 28514442 28089446 33961781 26186194 32707033
TRIB1 STK40 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 28514442 33961781 26186194 25852190 32707033
TRIB2 STK40 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 28514442 32707033 33961781
TRIB2 DET1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 28514442 32707033 33961781
TRIB1 DET1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 28514442 32707033 33961781
TP53 UBE2D1 â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
CUL4B DDA1 â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
CEBPA TRIB1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 26455797 30254053 30692133
TRIB2 RFWD2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 28514442 33961781 34646775 25311538 32707033
RFWD2 1433S â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 20843328 21625211
CUL4A DDA1 â—¼   PHYSICAL_INTERACTION 866.0 0.86 STRING 36370105
FOXO1 SFN â—¼   PHYSICAL_INTERACTION 866.0 0.86 STRING 36370105
FOSL2 STK40 â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
CUL4B CSN8 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 31973889 26496610 33961781 27173435 24981860 21145461
DET1 DDA1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 19295130 17452440 33961781
CUL4A CSN8 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 17079684 28514442 31973889 18606781 33961781 27173435 16964240 21145461 19295130
JUN FOSL2 â—¼   PHYSICAL_INTERACTION ✅ 0.87 0.87 mint 25609649
FOS RFWD2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 26496610 35140242 33961781 25609649 26186194
FOS STK40 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 35140242 33961781 25609649 26186194
RFWD2 ETV4 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 20062082 21572435 25117710 35140242 28373072
RFWD2 JUNB â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 25117710 33961781
2ABD TCPH â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28330616 19156129
TCPG TCPH â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 31536960 22863883 33961781 24981860 22939629 26344197
PP2AA TCPH â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 33961781 18782753 26496610 19156129
RCHY1 UBE2D2 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
RFWD2 TP53 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
DET1 RFWD2 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
ETV1 RFWD2 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
HSPA8 TP53 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
RFWD2 TRIB3 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
ETV5 RFWD2 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
RFWD2 TRIB1 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
RFWD2 STK40 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
ETV1 STK40 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
STK40 TRIB1 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
DDA1 CUL4B â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 31973889 26496610 21145461 19295130 16949367
CUL4B CSN2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 31973889 16861906 26496610 33961781 24981860 26186194 21145461
DDB1 DDA1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 20562859 17609381 17452440 16964240 26344197 19295130 16949367
MDM2 FOXO4 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 20874444 18665269 21525355
JUN STAT3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 10490649 16713569
DET1 CUL4A â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 33961781 17452440 16964240 14739464 16949367
JUNB JUND â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 33961781
RFWD2 JUND â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 12615916 23289756
RFWD2 ETS2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 25117710 26871468 26496610
ETS2 P53 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 18374905 26871468 26331536
TCPW TCPH â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 33961781 26344197
YWHAB YWHAZ â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
SIRT1 TP53 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
JUN RFWD2 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
COPS8 CUL4A â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
DDB1 RFWD2 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
RCHY1 TP53 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
CUL4A CUL4B â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17041588 31973889 23555860 18593899 33961781 16964240 21145461 30945288 32140073
CSN6 DDA1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 21145461 19615732 19295130 33961781
RFWD2 DDB1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17079684 25117710 33911083 17041588 32041890 31155351 19295130 14739464 16949367
DET1 DDB1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 33911083 33961781 31155351 17452440 16964240 14739464 16949367
DDB1 RBX1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 22118460 20870715 16473935 15448697 16678110 30349055 33504946 16751180
1433S MDM2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 19166854 17546054
TP53 RCHY1 â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 17568776 5220017
TP53 RCHY1 â—¼   COLOCALIZATION ✅ 0.89 0.89 mint 17568776 5220017
CSN6 CUL4A â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17079684 28514442 22474075 31973889 18606781 33179082 33961781 19295130 26186194 16964240 21145461 19615732 30945288
CUL4A CSN2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 31973889 18606781 32493769 26976604 27029275 33961781 26186194 16964240 25349427 21145461 19295130 32047038
RFWD2 TRIB3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 21572435 25117710 30692133 33961781 26186194 32707033 31125554
DET1 RFWD2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 21572435 25117710 33911083 32041890 30692133 33961781 31155351 17452440 14739464
ETV5 RFWD2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 20062082 21572435 28514442 25117710 33911083 35140242 33961781 26186194
RFWD2 CSN6 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 19295130 33101846 21625211
RFWD2 ETV1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 20062082 21572435 28514442 25117710 33961781 26186194
TCPB TCPW â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 22939629 33961781 26344197
TCPB TCPZ â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 22863883 33961781 24981860 22939629 26344197
COPS8 CUL4B â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
COPS6 CUL4A â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
COPS6 CUL4B â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
MDM4 UBE2D2 â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
JUN CDKN1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10700231 20566634 19959471
COPS2 CUL4A â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
RBX1 CUL4B â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 33969670 24292684 12481031 25189618 12609982 26496610 30349055 27113764 29499938 19250909 22038470 34026424 28446751 31973889 23238014 33961781 33504946 30945288 32140073
CSN6 CUL4B â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 31973889 26496610 22863883 33961781 26186194 19295130 21145461 19615732
CUL4B DDB1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19651607 33969670 33357448 28225217 24292684 25189618 21145461 18593899 26496610 16678110 16964240 33536335 27113764 29499938 30898011 28886238 29738775 17392787 29846670 22939629 22038470 34026424 16949367 31911655 28446751 17041588 23238014 31973889 16861906 33961781 30945288 26344197 32140073
CUL4A DDB1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 22952844 17079684 22118460 15448697 26613412 22910413 25349427 21145461 22474075 27462452 16473935 15811626 18606781 26231201 18593899 16678110 16964240 33536335 19295130 25982117 33759138 16260596 27113764 21113133 30898011 28886238 26976604 27203177 17392787 25795299 22939629 26344197 14739464 27294876 10585395 27573245 31911655 17041588 20870715 27203182 31973889 32235678 16861906 19966799 22342275 34251884 17626091 19287380 30945288 16949367 32140073
TP53 DDB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16357511 19382146
YWHAZ FOXO1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 11237865 8005530 3540605
YWHAZ FOXO4 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 14690436 8006586 0352724
SFN MDM2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 8007833 17546054 1210540
MDM4 MDM2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 10629057 32300648 25512388 21988832 25384516 25809483 17616658 25105592 12874296 31796886 29295817 32075226 20705607 17301054 22493164 25703327 27777309 29523541 27617579 23028042 20473904 22120712 22333590 22902369 22745160 12860999 19432880 21925390 28205554 25659040 19838211 33985974 16055726 25961923 32427989 18566590 22266850 18219319 29057323 10608892 30598450 29524278 25825738 17159902 24813712 31024344 27621617 15604276 29262653 19619542 10218570 28628118 16227609 10827196 12393902 24755078 20724842 34551723 27215386 11606419 20484049 12370303 23671280 26001071 26720344 33961781 12483531 23946421 19683495 26359458
MDM4 P53 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 10629057 29023092 30672125 31152661 17110929 19521340 10075736 30832340 22807444 12874296 25609649 11528400 24445145 17080083 18677113 20705607 27249653 9226370 17301054 18485870 26148237 27114532 16024788 22374672 24127580 18316739 26876197 29523541 21088494 23028042 24667498 30045945 20515689 25464845 22745160 19432880 21925390 28205554 20174603 21965653 25961923 21075307 22266850 8895579 28487147 32511789 10608892 30598450 25825738 19305137 19255450 11223036 15604276 16713569 28628118 16227609 10827196 12393902 20724842 24659749 12370303 23671280 17875722 33961781 31462704 26186194 23946421 31066983 19075013 15916963 19153082
PARP4 MVP â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 10477748 33961781 11855821 28514442
RBX1 CUL4A â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17079684 16189514 15448697 10230407 12481031 17452440 22474075 11861641 18593899 30349055 19295130 22405651 33759138 30352932 27113764 26976604 27203177 26990986 19250909 27203182 31973889 32235678 29958295 22863883 33961781 33504946 19287380 30945288 32140073
RBX1 NFKBIA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10230406 9859996 10066435
YWHAZ SFN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23840115 15161933
SFN YWHAZ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23840115 15161933
STAT3 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 16107692 23874455 20043094
STAT3 JUNB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10497240 17204573 9325164
TP53 MVP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19472297
RB1CC1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16061648 21775823
TP53 HSPA8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 31027880 18431400
RFWD2 CUL4A â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17079684 25117710 17041588 32041890 21145461 19295130 14739464 24298020
RFWD2 JUN â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 25117710 15994960 33961781 25609649 31155351 14739464 27534417 12615916
FOS JUND â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
FOS JUNB â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
RFWD2 P53 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15103385 16713569 23736031 29379285 16931761 21625211 27534417
RFWD2 TRIB1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 25117710 29296815 30692133 28089446 33961781 32707033 27041596
P53 1433S â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11896572 14517281 21625211 20206173 17546054
TCPH TCPA â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 16085932 22863883 33961781 9250675 22939629 26344197
PP2AA 2ABD â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 27880917 19156129 28330616 20220139 33961781 23135275 18782753 26344197
COPS2 CUL4B â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
FOSL2 JUN â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
FOSL2 JUNB â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
FOSL2 JUND â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
CUL4A DET1 â—¼   PHYSICAL_INTERACTION 903.0 0.9 STRING 36370105
COPS6 RBX1 â—¼   PHYSICAL_INTERACTION 907.0 0.9 STRING 36370105
2ABD TCPA â—¼   PROTEIN_INTERACTION 0.91 0.91 HIPPIE 28330616 19156129
CEBPA TRIB1 â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
MDM4 MDM2 â—¼   PHYSICAL_INTERACTION ✅ 0.93 0.93 mint 15604276 5217417
MDM4 MDM2 â—¼   COLOCALIZATION ✅ 0.93 0.93 mint 17159902 5219425
JUNB FOS â—¼   PHYSICAL_INTERACTION ✅ 0.93 0.93 mint 5218398 16511568
DDB1 DET1 â—¼   PHYSICAL_INTERACTION 934.0 0.93 STRING 36370105
JUN JUNB â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 28514442 33961781 25609649
FOSL2 JUND â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 28514442 26496610 12052862 33961781 26186194 20102225 10713367
TCPH TCPZ â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 28514442 22863883 33961781 24981860 22939629 26344197
PP2AA TCPG â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 18782753 26496610 19156129
PP2AA TCPZ â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 18782753 26496610 19156129
2ABD TCPB â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 28330616 19156129
TCPB TCPG â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 28514442 22863883 33961781 24981860 22939629 26344197
2ABD TCPG â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 28330616 19156129
TCPG TCPZ â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 28514442 22863883 33961781 24981860 22939629 26344197
TCPG TCPW â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 28514442 22939629 33961781 26344197
2ABD TCPZ â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 28330616 19156129
PP2AA TCPB â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 18782753 26496610 19156129
PP2AA TCPA â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 18782753 26496610 19156129
TCPA TCPZ â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 16085932 22939629 26344197
TP53 MDM4 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 7290688 19521340
TP53 MDM4 â—¼   COLOCALIZATION ✅ 0.96 0.96 mint 7290688 19521340
FOSL2 JUNB â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 32296183 16189514 14499865 26496610 33961781 26186194 20102225 19321746
TCPB TCPH â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 22863883 33961781 24981860 30021884 22939629 26344197
TCPA TCPG â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 16085932 22863883 33961781 22939629 26344197
P53 MDM2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 19303885 25417702 34408321 17268548 23252402 23880345 22807444 15094782 20962272 12529318 21726810 22124327 18981217 16173922 23318437 15558054 22524527 30584071 31626714 22301280 32516735 20174603 22912717 21075307 15848166 18566590 23483203 26882543 23402884 14671306 15001357 10889512 17908790 19411846 10640350 21561866 14499615 33503543 21986495 24998844 15908921 26673821 17098746 25362358 32066565 25739118 29295817 34362424 16595680 20591429 27336364 22745160 24462112 32427887 18467333 26578655 23261415 9271120 16055726 19357310 31591476 23169665 16338390 10608892 30464405 15542844 12612087 22266868 15550400 22331460 22914926 19071110 7686617 14559824 20959462 19941302 14596917 25512388 27129163 19597489 25609649 32904724 11351297 29121928 22487680 11709713 24127580 10562557 15358376 21584881 25312347 27826076 19098711 24980433 24413661 21887275 17116689 14612427 30948704 26001071 19857530 33061576 31138778 23802716 20234175 25313037 21988832 17616658 11744695 17666403 22525275 12897156 25156994 33020477 11925449 16152627 29876924 30244831 1614537 17363365 22474335 11112690 23443559 17297477 27905468 19085961 20479273 31940492 21261729 14517261 26908445 16866370 27893708 22653443 17470788 10488081 23370271 19223463 16751805 26556313 10734067 19411066 11223036 27856536 14704432 20124408 24240685 24842904 32901886 22948151 19234109 35140242 21084285 32894144 17848574 22737255 10561590 25168242 10435614 11697899 25543083 21572037 22920093 18604177 32874188 22659184 17591690 16845383 22444248 31239268 25283148 26186194 24200963 23826318 7689721 20047188 24314634 12167711 15308643 17318220 21857681 11431470 18815136 15950904 20705607 17525743 26876197 31177307 9529249 22374672 12915590 33650658 10601022 20837658 18223694 30097011 28205554 32334023 15247280 23776465 21268072 27308622 11713288 18234963 9582019 18784078 29487367 23776060 11713287 20484049 26720344 9131587 30109812 33961781 24361594 32807901 31066983 15824742 11562347 21454483 22157679 21088494 11070080 22575647 22083959 26540344 15210108 18332869 32528731 18172499 11094089 21132010 16414131 10827196 27031960 10892746 15280377 16023600 18665269 10202144 15058298 29549180 16212962 16905769 11278372 20657550 9809062 15295102 26238070 22391559 18061646 17310983 18485870 9278461 21925390 20659896 9824166 23150668 25637791 30598450 19160491 28605833 12690203 22467867 31594538 11572869 11384992 11486026 27807478 17936559 30679555 16678796 30252118 31652301 15144954 22411991 22084066 30175854 21478269 27543608 16624812 17290220 32097779 17301054 20694676 11714701 24667498 20395212 16547496 12381304 8058315 22266850 29755129 22085928 17159902 10196247 21316347 27886165 27215386 25384516 7926727 16964247 19081178 32198344 11046142 28549433 26350565 31533005 12867035 10321734 19590512 22991965 25277184 24207125 18541670 19166840 25103245 30320919 26883110 20235143 17139261 11597128 21071676 19568783 18813780 19805293 17056014 17989425 21317885 17234751 20588255 21170087 10347217 11839577 25954860 21060154 24926618 21750659 16331255 29269425 27811966 19305137 24659749 9450543 23201157 30879903 16870621 28362432 21149449 20570896 23609977 33765973 27106262 33355139 34040386 22588298 22389628 19033382 18264029 27462439 31092600 12208736 17369817 28082682 16579792 23246961 20708156 15013777 21465263 28542145 23572512 19483087 31665549 22975381 17438265 15604276 11178989 24488098 16432196 22227409 28628118 30005830 20639885 20847049 9363941 31406141 19816404 26475964 29899406 16861890 30320499 20660730 19332559 14702041 11284721 18316739 19837670 25464845 12426395 10681559 17302414 16107876 22510990 15154850 21098709 19106616 10722742 19188367 22366412 29524278 21084564 23134341 25624478 30455251 20173098 12620407 9223638 16713569 17426254 31647545 10766163 30454706 21471462 24621507 23652204 19153082 8875929 31152661 18309296 31968249 31796886 15122315 30532073 10980696 17080083 15064742 11285227 29547122 21965653 33495326 23728348 15242646 17347673 12842086 12944468 19255450 23671280 22916255 17875722 30355102 14741215 23946421 20591651 15053879 28514442 25241761 24567357 16215989 19656744 30832340 22262183 27249653 26203195 16857591 15313915 15933712 28223335 20542919 12552135 24643130 27282385 20080206 28553961 22819825 33579943 16159876 9724739 17380154 22318540 29997244 29670376 22103682 22032989 28394340 31903119
CSN8 CSN2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 25043011 11285227 9707402 10903862 22863883 33961781 11967155 26186194 27173435 24981860 22939629 16045761 26344197 11337588
CSN6 CSN2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 22939629 25043011 11285227 10903862 32034103 22863883 33961781 27173435 26186194 19615732 21145461 19295130 16045761 26344197 11337588
FOSL2 JUN â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 32296183 26496610 9160889 33961781 25609649 26186194 20102225 11708771
FOS JUNB â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 16189514 25416956 16511568 23661758 20211142 24029232 26496610 1406655 35140242 20195357 33961781 25609649 26186194 15867431 20102225 10764760
CSN8 CSN6 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 22939629 25043011 11285227 9707402 32034103 22863883 33961781 27173435 19295130 26186194 21145461 19615732 26344197 11337588
SFN TP53 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
DDB1 RBX1 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
MDM2 UBE2D2 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
CUL4B RBX1 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
RBX1 UBE2D2 â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
FOS JUN â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
COPS2 COPS8 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
COPS6 COPS8 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
CUL4A RBX1 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
TP53 MDM2 â—¼   PHYSICAL_INTERACTION ✅ 0.99 0.99 mint 17139261 5219401
JUND FOS â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 28514442 24029232 26496610 35140242 20195357 33961781 25609649 26186194 15867431 20102225 12193410 11431474
TCPA TCPB â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 16097032 14532270 16085932 22863883 33961781 30021884 22939629 26344197
DDA1 DDB1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
MDM2 UBE2D1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
CCT2 CCT6A â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CCT3 CCT6A â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CCT4 CCT6A â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CCT6A TCP1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CCT6A CCT7 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CCT6A CCT8 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
RBX1 UBE2D1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CUL4B DDB1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
CCT4 CCT8 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
CCT5 CCT6A â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
CCT2 CCT8 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT2 CCT3 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT3 CCT4 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT3 TCP1 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT3 CCT7 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT4 CCT5 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT4 CCT7 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT7 CCT8 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT8 TCP1 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
COPS2 COPS6 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT2 CCT7 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT2 TCP1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT2 CCT4 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT2 CCT5 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT3 CCT5 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT3 CCT8 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT4 TCP1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT5 TCP1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT5 CCT8 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT5 CCT7 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT7 TCP1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
MDM2 TP53 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
MDM2 MDM4 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
MDM4 TP53 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
TP53 CDKN1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 15145945 15988033 19235838 10516009 21478095 14984207 19427386
FOXO1 CDKN1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 21418583 17015685 12359217 12391153 11094066 18593906 19281796 18787071 23160481
FOXO4 CDKN1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11689711 15688030 15905404 10783894 12964026 20570964
FOXO1 CDKN1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 11073996 19380174 10783894 20673124 11094066 15668399 17646672 21708191 15084260 21613825 17940099 11994454 11154281
TP53 CDKN1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 21340684 20066118 20457558 20182602 6396087
FOXO4 CDKN1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 10783894 12391153 11313479 20673124 11094066 17646672 15509806 10217147 11994454
RCHY1 CDKN1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 21236467 18006823 19445020 19459846
RBX1 CUL4B â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 22466611 24127601 23973375 22466612 20541997 22466610 23906714 16751180 22902626
RBX1 DDB1 â—¼   PHYSICAL_INTERACTION 27.0 1.0 ACSN 11900249 12648680 12820959 15071497 15340381 15459660 15688063 1570337 15703371 16697054 17884153 18381890 18931676 19270156 19440234 19557001 19622404 19686080 19809470 19847258 20211143 20457011 22257761 22373527 22615860 22824526 23085398
CUL4A DDB1 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
DDB1 CUL4A â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 11900249 12648680 12820959 15071497 15340381 15459660 15688063 1570337 15703371 16697054 17884153 18931676 19270156 19557001 19622404 19686080 19809470 19847258 20211143
RBX1 DDB1 â—¼   SHARES_COMPLEX 27.0 1.0 ACSN 11900249 12648680 12820959 15071497 15340381 15459660 15688063 1570337 15703371 16697054 17884153 18381890 18931676 19270156 19440234 19557001 19622404 19686080 19809470 19847258 20211143 20457011 22257761 22373527 22615860 22824526 23085398
DDB1 CUL4A â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 11900249 12648680 12820959 15071497 15340381 15459660 15688063 1570337 15703371 16697054 17884153 18931676 19270156 19557001 19622404 19686080 19809470 19847258 20211143
SIRT1 FOXO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 24003218 22013015 14976264 18235501 15220471 14980222 22395773 15788402 15692560
SIRT1 FOXO4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23331499 15126506 10102273
TP53 MDM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 201.0 1.0 Omnipath 23150757 20948295 10871862 10914734 21422812 21957016 14532965 22290440 20663877 20547751 11591713 24339722 11840331 22223137 16492744 15843377 22948151 7888679 20156675 21217645 22180176 8319905 9707425 15831521 17690113 9649502 10688649 9194564 15917661 15090541 20837136 8187772 10788589 17907153 15192123 8440237 11964305 16510138 10856296 15580300 7624148 12208736 21211512 16624812 17848574 11245471 21637567 20588255 10562557 9525742 9270029 16479015 19941079 14602726 15024021 18814047 20036872 10718212 18852133 12374749 18397889 25016801 12755686 22081073 22245141 23365201 8957072 22197810 15856024 20703075 23483203 9645455 19648117 20331637 22301280 14743206 23982177 9486848 15734740 19638633 19671680 17310983 10469568 20659896 10072445 21097889 17237821 11748232 11085543 21750655 16337599 21295542 1614537 9815889 9070662 16585169 9472631 17936559 17139261 11328884 12887889 20858413 9858609 14610316 20080970 19505873 11313463 15684615 18359851 18783169 16202543 9267820 12235242 14990790 15851483 7587074 18336191 21478269 17043642 15361831 18025460 23612020 10208414 11756653 24389645 9071998 9430645 9400998 9371494 23149414 22532570 9271120 10777217 22383580 18781178 12606552 14514686 17318220 11127813 16571800 19085961 9207798 10891494 10065155 11593391 14570892 12902982 19649205 20124454 17390010 19955655 12138177 19663772 23581014 15908423 10321740 23150759 19837670 10348346 18632610 9294611 11956627 12750288 12851404 8313378 9135153 15735665 7958853 8247544 9535786 16501602 18566224 8910340 11046142 9405685 7936649 12173040 17329361 21451571 14704432 23874713 18333294 19541936 22787160 18585004 22085928 12080472 7651818 11179471 10949923 19428175 15592502 8413278 11714701 10566557 18583933 9681831 15550242 15007388 19590512
MDM2 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 559.0 1.0 Omnipath 20657550 30005830 17616658 9529249 10321734 33650658 9724739 24462112 24621507 15933712 23826318 24667498 22948151 22653443 23776060 25313037 25241761 19303885 16857591 23246961 19033382 20591651 21149449 25417702 15122315 16579792 27543608 29670376 12208736 17848574 26673821 25277184 23443559 23318437 21060154 15210108 19805293 8875929 8058315 21471462 17879958 25362358 23169665 22301280 21584881 20124408 10980696 26876197 17310983 17380154 15058298 24567357 18665269 30109812 25637791 18467333 22337874 22227409 22389628 15242646 22510990 15950904 15001357 19483087 26540344 14559824 21986495 26556313 20708156 19901969 33765973 32528731 11562347 10202144 22374672 10722742 22083959 21965653 17098746 19234109 30679555 16107876 12690203 22525275 19071110 28542145 12620407 20837658 27129163 9131587 24240685 27031960 10681559 19305137 11744695 19188367 16023600 24659749 17347673 12944468 20395212 22084066 20639885 21454483 12897156 16432196 10347217 10706102 11178989 20174603 16751805 15542844 12842086 11431470 11384992 25739118 15064742 23402884 27462439 16905769 22124327 27215386 12867035 22588298 27336364 14702041 16152627 23776465 22262183 21132010 19411846 18309296 23483203 11709713 18981217 14612427 22920093 23671280 24980433 27905468 25168242 21750659 26238070 22737255 23609977 27282385 20847049 20705607 21075307 28082682 17297477 11697899 17936559 24361594 19098711 15469934 34591612 24998844 16212962 11094089 12915590 17116689 11713288 15144954 23201157 10608892 17591690 25156994 17301054 22444248 26883110 26001071 19160491 22157679 24413661 19357310 23802716 15280377 21317885 11597128 19579266 25624478 18061646 21088494 9223638 10435614 31177307 11331603 22391559 20570896 19941302 9278461 18485870 15604276 18566590 12612087 11046142 14704432 26186194 10935507 16173922 14596917 17159902 25543083 19656744 15848166 18316739 22266868 17056014 19255450 21561866 19590512 11839577 22991965 22266850 24200963 11285227 11713287 22975381 19081178 20660730 26475964 16678796 23261415 20173098 17666403 25464845 32427887 23252402 17438265 20959462 22659184 17470788 22912717 17080083 15247280 19332559 17989425 16870621 18813780 20235143 11278372 10562557 25609649 10561590 19411066 17908790 19568783 7926727 21925390 21988832 24127580 18604177 14499615 17371838 17525743 33061576 21887275 26578655 21084564 16861890 20694676 12552135 22914926 17363365 24643130 1614537 22916255 12381304 34992144 12167711 19857530 15053879 10889512 11486026 22103682 16713569 17110336 17426254 10640350 21316347 21478269 15154850 12529318 16595680 16414131 19597489 23880345 27893708 7686617 27811966 17318220 29997244 27308622 19166840 35044719 16159876 24314634 15313915 25283148 22032989 24926618 18172499 19837670 16215989 23134341 26908445 9824166 18451149 21170087 23572512 21465263 22807444 15013777 16845383 10488081 23946421 11714701 25384516 22474335 25312347 23370271 23150757 18541670 22318540 11925449 21572037 24488098 32066565 17268548 20542919 11572869 16338390 21857681 23150668 19223463 20234175 20484049 11070080 20591429 22575647 11351297 16624812 22411991 20588255 17369817 11223036 15908921 9582019 25103245 17302414 21071676 9450543 31968249 34562520 18332869 14671306 21084285 27856536 30464405 26882543 21726810 33020477 21261729 21268072 12426395 16964247 20659896 19106616 22331460 23728348 10827196 22524527 21098709 9363941 17139261 20080206 14517261 22487680 31652301 17290220 27106262 16866370 24207125 28223335 9271120 15550400 7689721 26350565 10196247 27807478 10766163 15558054 35371302 26203195 29487367 25512388 25954860 18223694 15824742 24842904 14741215 16055726 22085928 32894144 18234963 17875722 18815136 15295102 15308643 15358376 22819825 15094782
MDM2 MDM4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 69.0 1.0 Omnipath 17145710 10218570 17616658 16511560 22266850 12874296 21925390 25825738 21988832 25512388 16227609 22493164 22902369 25659040 18219319 12963717 15604276 18566590 12370303 19838211 26359458 27617579 25809483 34551723 10608892 23028042 22120712 25703327 12860999 32300648 16055726 24813712 17301054 12483531 23671280 17159902 27621617 25105592 20484049 20724842 27215386 10827196 26001071 11606419 23946421 19683495 20705607 24755078 25384516 20473904 12393902
TP53 MDM4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 16492744 18172009 21750655 20036872 21422812 17510313 9926934 18336191 19521340 20372076 10469568 20080970 22290440 21394211 23474762
MDM4 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 74.0 1.0 Omnipath 25609649 18677113 28487147 24445145 30045945 20515689 26148237 22266850 11528400 19521340 21088494 16713569 15916963 9226370 12874296 21925390 16024788 25825738 24667498 16227609 24127580 8895579 20174603 18485870 12963717 15604276 25464845 12370303 10608892 23028042 25961923 26186194 17110929 22374672 26876197 17301054 23671280 21965653 17875722 22807444 10075736 19305137 17080083 29023092 27114532 20724842 10827196 19255450 24659749 28035068 23946421 20705607 19075013 21075307 12393902 11223036
PTPN11 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 10409724 23331499 18508557 12040451 16189514 11594781
SPOP RBX1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 20360384 19684112 19955409 20154143 20956384 19818708
UBE2D1 RBX1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10878807 9891082 12101228 10535940 12538644 11454738 22286099 10973499
UBE2D2 RBX1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10878807 9891082 12101228 10535940 12538644 11454738 22286099 10973499
NFKBIA RBX1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 9990852 10514433 9859996 9990853 7628694
RBX1 CUL4A â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 11900249 12648680 12820959 15071497 15340381 15459660 15688063 1570337 15703371 16697054 17884153 18931676 19270156 19557001 19622404 19686080 19809470 19847258 20211143
RBX1 CUL4A â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 11900249 12648680 12820959 15071497 15340381 15459660 15688063 1570337 15703371 16697054 17884153 18931676 19270156 19557001 19622404 19686080 19809470 19847258 20211143
RBX1 NFKBIA â—¼   ENZYMATIC_REACTION ✅ 19.0 1.0 ACSN 10066435 11900249 12648680 12820959 15071497 15340381 15459660 15688063 15703371 16697054 17884153 18931676 19150432 19270156 19622404 19686080 19809470 19847258 9859996
TP53 SFN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 18281511 10101800 22427654 12640112 17404570 12447694 17361185
TP53 SFN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 20206173 17546054 18431400 21340684 20066118 20457558 20182602 11896572 6396087 14517281 21625211
SIRT1 NFKBIA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19408108 15152190
SIRT1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 21.0 1.0 Omnipath 18235502 11672523 18235501 15205477 35931247 15989956 17964266 25280219 19047049 16713569 19960022 21245319 12006491 19590512
STAT3 FOS â—¼   UP_REGULATES ✅ + 38.0 1.0 ACSN 10347215 11528470 12223527 13130303 14607900 14670306 15218058 15356132 15573129 15810077 16418395 16716598 16831886 17403902 18297062 18776941 18832382 19380816 19412634 20093776 20237412 20406969 20581311 21317430 21840487 21883379 22006115 22943793 22945800 23124025 23454751 23953057 24857661 27216177 28186502 7543512 7768934 9278421
STAT3 FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 17204573 14737107 12640143 12600988 11685114 8071311 15040450 16293640
PTPN1 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 15821101 23331499 11970898
JUN TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 22859294 17321721 20697347 10348347 12963547 10072388 22353755 18604200
TP53 FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 8604347 17174366 8668332 1946467 10082525 10214938 1508692 8649776 10529369 12173040
TP53 FASN â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 12734185 19861536
UBE2D1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 15169778 15340381 15147722 12820959 10722742 19459846 18006823 10721693 19440234
RCHY1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 23.0 1.0 Omnipath 21988832 19483087 17568776 24367557 25116336 21084285 12654245 21791603 20452352 19043414 16713569 31630802 27519799 19918835
PTPN1 NFKBIA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 8940099
UBE2D2 NFKBIA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 10329681
JUN FOS â—¼   PHYSICAL_INTERACTION 21.0 1.0 ACSN 10606235 11274345 11274400 14673140 15067049 16393692 16394015 17439715 18222063 18754863 19667062 19846528 21385848 21790308 22381618 22634314 22723415 23430059 26587781 8545107 9064320
JUN FOS â—¼   PROTEIN_INTERACTION 21.0 1.0 ACSN 10606235 11274345 11274400 14673140 15067049 16393692 16394015 17439715 18222063 18754863 19667062 19846528 21385848 21790308 22381618 22634314 22723415 23430059 26587781 8545107 9064320
JUN FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 2513130 14561487 8617996 8934539 19255142 9217081 12760745 2498806 10521486 8597411 10858536 12392213 9819441 1380150 23562910 1944274 9867253 9571041 1900040 2511006 14684847 15467742 12231642 11950097
FOS JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 73.0 1.0 Omnipath 20498278 16714286 21675959 25609649 23602568 9872330 20102225 8380166 18848838 18535250 2516828 8397339 15867431 18172215 9346889 10779323 9732876 16928824 26496610 15994313 22719067 24029232 16511568 20195357 11053448 20936779 26186194 18619508 20511396 16008525 10488148 21199371 8617242 17440114 16055710 15319445 11090181 9160889 23661758 1631061 15718494 11431474 31515488 8440710 7816143 20410304 34671206
JUN FOSL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 25609649 26186194 9160889 11708771 20102225 26496610 32296183
JUNB FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 1380150 2116003 8934539 11698415 9813041