MYO6
|
RNF11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15231748
5217094
|
RNF11
|
ITCH
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
8012720
20676133
|
RNF11
|
OPTN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15231748
5217094
|
RNF11
|
TNIP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15231748
5217094
|
RNF11
|
RIPK1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
ACSN
|
19131965
23010170
|
RNF11
|
RIPK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
19131965
|
OPTN
|
TNIP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
8153045
21516116
|
ITCH
|
TRAF6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
813.0
|
0.81
|
STRING
|
36370105
|
APEX1
|
TAXB1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28986522
33545068
|
EMIL1
|
TRAF6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
TRAF6
|
CACO2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33815386
21988832
|
TAXB1
|
OPTN
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
19609363
33545068
|
OPTN
|
CACO2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
31723608
33545068
|
RIPK1
|
TAXB1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
19131965
18246070
|
ITCH
|
TAXB1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
18246070
33545068
|
CACO2
|
TRAF3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
29146913
33545068
|
TRAF3
|
TAXB1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33545068
21885437
|
RFWD2
|
TAXB1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
TNIP1
|
NBR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
30561431
33545068
|
TNIP1
|
MLP3B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
25416956
33545068
|
PRKN2
|
SQSTM
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
26746706
24906799
26364802
20890124
23503661
|
TNAP3
|
SQSTM
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33545068
28574503
|
CACO2
|
SQSTM
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
21079414
33545068
|
RABX5
|
TAXB1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
NCOA4
|
TAXB1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33545068
28877469
|
TAXB1
|
TBC15
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
32296183
33545068
|
ERD21
|
TAXB1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
S22AN
|
TAXB1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
PRKN2
|
TAXB1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
23503661
31723608
|
RN115
|
TAXB1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
MLP3B
|
CACO2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
25771791
33545068
|
TNAP3
|
CACO2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
30561431
33545068
|
ERD21
|
RN115
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
FHL5
|
TAXB1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
OPTN
|
PRKN2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
31723608
25294927
|
CR001
|
ITCH
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
TAXB1
|
NBR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
31723608
33226137
33545068
|
TNAP3
|
TBK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
30561431
19615732
15661910
21885437
|
TAXB1
|
TBK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
31723608
28877469
21885437
|
TAXB1
|
RHG01
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
33545068
14697242
|
SQSTM
|
TAXB1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
31723608
28820283
33545068
|
REEP4
|
TAXB1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
TAXB1
|
GBRL1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
31723608
32296183
26451915
|
CR001
|
TAXB1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
TAXB1
|
GBRL2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
32296183
26451915
33545068
|
RN126
|
TAXB1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
LEG8
|
S22AN
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
CACO2
|
GBRL1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
32296183
16189514
25771791
25416956
|
OPTN
|
RIPK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
838.0
|
0.83
|
STRING
|
36370105
|
GBRL2
|
OPTN
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
31723608
21617041
|
GBRL1
|
NBR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
19250911
20562859
|
MLP3B
|
TBK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
33545068
21617041
|
TBK1
|
SQSTM
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
32835772
27035970
25972374
33545068
31810986
|
OPTN
|
MYO6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
20161783
26971995
19805065
15837803
26451915
|
MLP3B
|
TAXB1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
26451915
23209807
33545068
|
MLP3B
|
GBRL2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
20562859
33545068
24582747
|
TRAF6
|
RN126
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
14743216
22493164
|
MLP3B
|
NBR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
31857374
24879152
19250911
20562859
33545068
|
GBRL1
|
OPTN
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
31723608
21617041
|
OPTN
|
TBC15
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
32296183
25416956
33545068
32814053
31723608
|
TNAP3
|
RIPK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
29274253
32015333
22585859
19131965
15258597
18246070
30561431
|
TNIP1
|
TAXB1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
32296183
25416956
21885437
33545068
30561431
|
CACO2
|
TAXB1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
29146913
33545068
17635994
|
TAXB1
|
EMIL1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
32296183
25416956
33961781
|
CACO2
|
GBRL2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
32296183
16189514
25416956
33545068
32296703
25771791
|
RNF11
|
TAXB1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
19131965
15231748
|
RIPK1
|
TRAF3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
8612133
32296183
|
LEG8
|
TAXB1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
28514442
29892012
25416956
32296183
34225486
27693506
33961781
26186194
|
MYO6
|
CACO2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
31744880
26971995
26451915
17635994
|
MYO6
|
TAXB1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
29940186
26971995
26451915
17635994
|
TAXB1
|
TRAF6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
10920205
17703191
18239685
21988832
|
TRAF6
|
SQSTM
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
16189514
30281815
10747026
23017601
15870274
27458013
19903815
31281713
15340068
11244088
17389358
23911927
19201866
32265222
27681126
26279575
16874300
32384667
20974803
28244869
|
TRAF6
|
TNAP3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
23737552
23018911
21220427
29720226
23105109
28244869
11463333
9928991
15334086
31625129
32015333
20622874
18164316
|
ITCH
|
RNF11
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28292929
19131965
31985874
20676133
22507528
14559117
|
RNF11
|
TNAP3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
22507528
19131965
15231748
23018911
|
MLP3B
|
OPTN
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
25026213
23805866
30679426
21617041
32296703
|
OPTN
|
SQSTM
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
31723608
25026213
33545068
|
RIPK1
|
SQSTM
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
32707033
10356400
26416459
|
TRAF3
|
TBK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
22330071
32324863
29125880
27135603
22792062
23986588
20174559
22079989
22908223
33608556
28049150
32779804
24763515
33372174
24622840
23717208
19380580
23308279
34084167
17991829
29920243
33187908
26928339
33411856
31404116
|
NBR1
|
GBRL2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
19250911
20562859
33545068
|
TBK1
|
CACO2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
19820708
33545068
30309841
33961781
32707033
21903422
|
TNIP1
|
TNAP3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
32296183
25416956
16713569
10385526
21988832
18029035
12586352
25165885
11389905
12965196
30561431
|
SQSTM
|
GBRL1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
32296183
16189514
25416956
31006538
19250911
20562859
21617041
21691068
|
TBK1
|
OPTN
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.9
|
0.9
|
mint
|
18307994
6492190
|
TNIP1
|
OPTN
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
32296183
25416956
21988832
25910212
33545068
33961781
23414517
21516116
26871637
30561431
|
OPTN
|
TBK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
27086836
25923723
32556086
29395067
27035970
27538435
25803835
26365381
20174559
27620379
30327196
23414517
18307994
31723608
32707033
21903422
|
SQSTM
|
NBR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
21935636
34037656
24879152
30581152
32123815
19250911
20562859
33226137
33545068
25007327
34079125
29343546
20808283
16861740
12813044
15802564
|
SQSTM
|
MLP3B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
25416956
33302793
19250911
18083104
30853400
32296703
27554286
28855742
30633346
32296183
22434781
20562859
24089205
33436498
31286822
33545068
26413874
28085563
24582747
29426817
34084775
31006538
29416008
23333919
16169070
27791183
23878278
21900206
24023838
31857374
27158844
20010802
25007327
24668264
26524528
|
SQSTM
|
GBRL2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
21900206
32296183
16189514
25416956
31006538
17353931
19250911
20562859
24089205
33436498
33545068
29426817
24582747
21516116
32296703
21460636
|
TAXB1
|
TNAP3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
32296183
23018911
10435631
11389905
33961781
30561431
|
CACO2
|
LEG8
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
32296183
16189514
25416956
29892012
34225486
27693506
23511477
33961781
23386746
26186194
25771791
|
TBK1
|
TRAF3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
941.0
|
0.94
|
STRING
|
36370105
|
TNIP1
|
OPTN
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.96
|
0.96
|
mint
|
8153045
21516116
|
OPTN
|
TBK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
980.0
|
0.98
|
STRING
|
36370105
|
RNF11
|
ITCH
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
14559117
19131965
|
TBK1
|
OPTN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
50.0
|
1.0
|
Omnipath
|
27247382
29246869
29594070
27035970
21617041
18307994
22364875
29755463
21903422
26376340
29867991
23794264
26101267
26365381
21862579
27538435
25026213
25923723
29282133
29626651
29971063
30294276
30223576
20174559
26266977
23414517
27086836
23178947
22518139
27906974
25803835
|
ITCH
|
RIPK1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
10.0
|
1.0
|
ACSN
|
10940313
11318614
16469705
16861923
18552861
18628966
19131965
20068034
21107885
21383157
|
TRAF3
|
TBK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
Reactome
|
12692549
15210742
16306936
16281057
14530355
17526488
17047224
14703513
23453971
|
TRAF3
|
TBK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
20.0
|
1.0
|
Omnipath
|
27135603
15210743
16127453
15210742
16306936
12702806
23986588
22792062
16177806
20389019
17991829
20174559
16858409
23717208
34084167
22330071
17468758
17327220
24622840
|