Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
GNB2 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
GNB2 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
MYC PTPA â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12747840
TCP1 CAPN12 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
ACTB HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
APEX1 ACTB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16431169 11082319
FYN AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RAF1 AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19197339 7014125
HTT AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HSP90AA1 AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12799359 11988487
AKT1 PTK6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15539407 20606012
ESR2 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16549430 17261755
MAPK8 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16306447
AKT1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17942906 9804616
ARL2BP TCP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
BBS10 TCP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0910268107 20080638
BBS10 BBS12 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0910268107 20080638
BBS10 BBS7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0910268107 20080638
BBS12 BBS10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0910268107 20080638
BBS12 TCP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0910268107 20080638
BBS12 CCT5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0910268107 20080638
BBS12 CCT4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0910268107 20080638
BBS12 CCT2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0910268107 20080638
BBS12 CCT3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0910268107 20080638
BBS12 CCT8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0910268107 20080638
BBS7 CCT3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0910268107 20080638
BBS7 TCP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0910268107 20080638
BBS7 CCT4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0910268107 20080638
RYBP BMI1 â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 24981860
TCP1 CCDC71 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
HTT CCNC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CCT2 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CCT2 PFDN1 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
CCT2 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CCT2 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
CCT2 TBK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TRAF3IP3 CCT3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
CCT3 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CCT3 TBK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CCT3 RAF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216198 12620389
CCT3 MAP3K1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CCT3 PFDN1 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
CCT3 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
MYC CCT3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11983916
YWHAZ CCT4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
CCT4 TBK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CCT4 MAP3K1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CCT4 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CCT4 PFDN1 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
TRAF3IP3 CCT5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
CCT5 TBK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CCT5 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CCT5 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CCT5 MAP3K1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CCT5 IKBKE â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CCT5 PFDN1 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
CCT8 CCT6A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
CCT6A YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
CCT6A MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CCT6A MAP3K1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CCT6A TBK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CCT6A PFDN1 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
YWHAZ CCT7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
CCT7 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CCT7 PFDN1 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
CCT7 TBK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TRAF3IP3 CCT8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
CCT8 MAP3K1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CCT8 TBK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CCT8 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CCT8 VBP1 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
CCT8 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CCT8 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
CCT8 PFDN2 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
CCT8 PFDN1 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
CDC5L HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CDK1 MAPK6 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 18235225 20236090
YWHAZ CDK18 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
PPIA CDK5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
COPS5 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18926707
COPS5 TYK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24043623
CUL3 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
DCAF7 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SUV39H1 DCAF8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
FYN FANCA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
FRAS1 TCP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
HDAC6 FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
SUV39H1 FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
LCK FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8946678 9973466
MKI67 FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
FYN RIN3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
FYN SUV39H2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
FYN MAP4K1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
FYN LCK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17570479 22043010
GABARAP HDAC5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
TCP1 GBA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21098288 1014376107
GPR37 PPM1J â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
SMAD3 HDAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10199400 11427533
L3MBTL2 HDAC3 â—¼   COLOCALIZATION 2.0 0.8 intact 7719892 20385135
HDAC3 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 22002311 18483244
HDAC6 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TUBA1A HDAC6 â—¼   DEACETYLATION ✅ 2.0 0.8 intact 5215415 12024216
YWHAZ HSP90AA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
HSP90AA1 MAP3K1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSP90AA1 IKBKE â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
YWHAZ HSP90AB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
HSP90AB1 IKBKE â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSP90AB1 MAP3K1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSP90AB1 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
MYC HSP90AB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11983916
HSPA4 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
HSPA4 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TUBA1A HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RYBP HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SNW1 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
POC1A HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTT TCP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
LRRK2 TTLL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
MAP3K3 MAP2K5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TCP1 MAP3K1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TUBA1A MAP3K1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TNFRSF1B MAP3K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12517920
TCP1 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
YWHAZ MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
PFDN1 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
PFDN2 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
VBP1 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TUBA1A MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TUBB3 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
MYC VCAM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11318876 10528192
TCP1 NPAS4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PDK1 TSSK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16336268
PFDN1 TCP1 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
TCP1 PIK3R6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
YWHAZ PPIA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
TCP1 SCN4A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
SNW1 SMAD3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5213835 11278756
TCP1 TBK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TRAF3IP3 TCP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
TCP1 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
TCP1 TNFRSF1B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TCP1 TTLL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
ZNF143 TCP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10893243
ZNF76 TCP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10893243
YWHAZ TUBA1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
TUBA1B YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
WDR77 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
CCT2 CCT4 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
CCT4 PFDN2 â—¼   PHYSICAL_INTERACTION 804.0 0.8 STRING 36370105
CCT5 PFDN2 â—¼   PHYSICAL_INTERACTION 804.0 0.8 STRING 36370105
CCT6A PFDN2 â—¼   PHYSICAL_INTERACTION 804.0 0.8 STRING 36370105
CCT7 PFDN2 â—¼   PHYSICAL_INTERACTION 804.0 0.8 STRING 36370105
PFDN2 TCP1 â—¼   PHYSICAL_INTERACTION 804.0 0.8 STRING 36370105
COPS5 ERCC8 â—¼   PHYSICAL_INTERACTION 805.0 0.8 STRING 36370105
METTL14 METTL3 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
HSP90AB1 LRRK2 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
ITGA4 YWHAZ â—¼   PHYSICAL_INTERACTION 808.0 0.8 STRING 36370105
CCT2 VBP1 â—¼   PHYSICAL_INTERACTION 811.0 0.81 STRING 36370105
CCT3 CDC20 â—¼   PHYSICAL_INTERACTION 811.0 0.81 STRING 36370105
CCT3 VBP1 â—¼   PHYSICAL_INTERACTION 811.0 0.81 STRING 36370105
CCT4 VBP1 â—¼   PHYSICAL_INTERACTION 811.0 0.81 STRING 36370105
CCT5 VBP1 â—¼   PHYSICAL_INTERACTION 811.0 0.81 STRING 36370105
CCT6A VBP1 â—¼   PHYSICAL_INTERACTION 811.0 0.81 STRING 36370105
CCT7 VBP1 â—¼   PHYSICAL_INTERACTION 811.0 0.81 STRING 36370105
CCT7 CDC20 â—¼   PHYSICAL_INTERACTION 811.0 0.81 STRING 36370105
CFTR YWHAZ â—¼   PHYSICAL_INTERACTION 812.0 0.81 STRING 36370105
CCT4 CCT6A â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
CCT2 PFDN2 â—¼   PHYSICAL_INTERACTION 815.0 0.81 STRING 36370105
CCT3 PFDN2 â—¼   PHYSICAL_INTERACTION 815.0 0.81 STRING 36370105
CCT2 TCP1 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
AKT1 HSP90AB1 â—¼   PHYSICAL_INTERACTION 820.0 0.82 STRING 36370105
BBS7 RFWD3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
BBS7 MKKS â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22500027 20080638
PCGF6 BMI1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 12167161 24981860
BMI1 SNW1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 34316702 24457600
BMI1 EEA1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 34316702 24457600
MYC CDC5L â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
MYC CDK1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17314511 29467282
VCAM1 CDK1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
LRRK2 CDK5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31046837 26268594
RAF1 DCAF8 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 16364241 34017080
DOCK5 MKS1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
TBL1Y HDAC3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
LRRK1 LRRK2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 20144646 19712061
MYC TTC27 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17314511 29467282
MYC WDR82 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
VCAM1 PPIA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
CDC20 CDK1 â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
TCP1 VBP1 â—¼   PHYSICAL_INTERACTION 827.0 0.82 STRING 36370105
BBS7 BBS12 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 22500027 20080638
WDR83 CDC5L â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
HDAC6 CFTR â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 31501480 14675537 22069321
GAN CUL3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 15983046 31944090 21145461
DCAF7 PCGF5 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 24981860 27705803
HDAC1 ZBTB2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 26496610 23752268 28514442 33301849
RAF1 LCK â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 8939988 16189514
SNW1 MYC â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 30415952 29467282 19818711
MYC PCGF6 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 30415952 35140242 29467282
WDR83 SNW1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
WDR5 SOX2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 30089852 29383478 35140242
ARAF YWHAZ â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
CFTR HSPA4 â—¼   PHYSICAL_INTERACTION 832.0 0.83 STRING 36370105
FBXW4 TXNDC9 â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
LRRK2 TUBA1A â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
MYC ACTB â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 29467282 11839798
ESR2 ACTB â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 21182203 21951318
AKT1 FANCA â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 14499622 11855836
CDK1 CDC20 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 28514442 26912231 10799291
SOX2 CDK1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 23667531 30297536
DERL1 CFTR â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 26618866 16954204 16901789 18555783
LRRK2 TTC27 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 31046837 29513927
CCT2 MKKS â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
CCT8 CDC20 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
CCT3 CCT5 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
CCT6A CDC20 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
KRAS NRAS â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
CCT5 CCT7 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
ARAF KRAS â—¼   PHYSICAL_INTERACTION 849.0 0.84 STRING 36370105
HDAC3 AKT1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 29523594 20026773
MYC HDAC3 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 18483244 31155734 22002311 23079660
PCGF6 WDR5 â—¼   PHYSICAL_INTERACTION 850.0 0.85 STRING 36370105
PDK4 PDK3 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33961781 28514442 32707033
CCT5 CCT8 â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
CCT4 CDC20 â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
CCT7 IGBP1 â—¼   PHYSICAL_INTERACTION 855.0 0.85 STRING 36370105
HDAC1 SOX2 â—¼   PHYSICAL_INTERACTION 856.0 0.85 STRING 36370105
CCT2 CCT3 â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
LCK CDK1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 31980649 34079125
SOX2 EHMT2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 35140242 23667531
PEX14 PEX7 â—¼   PHYSICAL_INTERACTION 860.0 0.86 STRING 36370105
CCT2 CCT7 â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
CCT2 CDC20 â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
ACTB ACTL6A â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
ARAF RAF1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 34017080 20130576 31980649
MKS1 B9D1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 32726168 27173435 26638075
HDAC1 EHMT2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 16287849 26496610 23752268 28514442 26028330
PCGF6 HDAC1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 22325352 27705803
HDAC1 VHL â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 22286234 11641274
HDAC1 WDR5 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 22689669 26186194 23752268 27705803 28514442 33022573
SOX2 HDAC3 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 35140242 23667531 21532573
IKBKE TBK1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
ILK RAF1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 25852190 23455922 26496610
STK4 MAP1B â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 23455922 24366813 20562859
MYC WDR5 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 31767764 35140242 17353931 29467282 30415952 27320920
FYCO1 MAP1LC3B â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
GABARAPL2 ZBTB2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
CCT2 CCT8 â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
HSPA4 PARK2 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
NRAS RAF1 â—¼   RELOCALIZATION ✅ + 0.87 0.87 Signor 21779497
RFWD2 TRIB3 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
VBP1 VHL â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
PDK1 PDK3 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
CCT6A TCP1 â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
TUBA1B TUBA1C â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
PPP2R2A PPP2R2D â—¼   PHYSICAL_INTERACTION 879.0 0.87 STRING 36370105
ILK AKT1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 11825911 11546794 11313365 18339839 11278835 12149249 14500673 9736715 12176337 11445557 16189514
AKT1 PDK1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 34278744 27505672 27166089
AKT1 RAF1 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
YWHAZ ARAF â—¼   PHYSICAL_INTERACTION ✅ 0.88 0.88 mint 8009399 19933840
BBS7 BBS10 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 28514442 20080638
SOCS1 FYN â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 10022833 16713569 29991678
HDAC5 HDAC3 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 11931768 11804585 21081666 11466315 10869435 10220385
IRAK1 IRF7 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 15767370 21903422
MAP1B LRRK2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 21159966 24754922
L3MBTL2 RYBP â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
HDAC6 HSP90AA1 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
HDAC6 TUBA1A â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
MAP3K1 MAPK8 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
PCGF5 RYBP â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
PFDN2 VBP1 â—¼   CORRELATES + 0.88 0.88 CCLE 31978347
HSP90AA1 HSP90AB1 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
SNW1 CDC5L â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 26344197 29395067 12840015 20467437
DCAF7 RYBP â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 24981860 34316702 27705803 28514442
TYK2 FYN â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 9196040 16713569 16189514
RAF1 FYN â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 7517401 16189514 16713569
L3MBTL2 PCGF6 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
SMAD3 SNW1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 11278756 18729074
COPS5 VHL â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
COPS5 DDB2 â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
BMI1 RYBP â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
CCT6A CCT7 â—¼   CORRELATES + 0.89 0.89 CCLE 31978347
CDC5L ZRANB1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
CCT6A CCT8 â—¼   CORRELATES + 0.89 0.89 CCLE 31978347
MYC PRKN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20638938 15078880 23277542
DYNC2I2 MAPK6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
MYC TUBG2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
AKT1 SMAD3 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 25241761 16362038
TNK2 AKT1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 10652228 11394904 18470881
MYC AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16846534 16489011 18562319
MAPK6 BBS10 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
BBS10 HDAC6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
MYC CCT5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
KRAS CCT7 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
CDK1 NME1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18234856
CUL3 HDAC1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 15467454 15688063 17312394
FYN TUBA1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 7678277 11826099
YWHAZ GABARAPL2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
MYC HDAC1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 34147029 22286234 26496610 30415952 18271930 17314511 18003922 24951594
HDAC1 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11306568 19049980 10575014
MYC HDAC3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
NRAS HSP90AA1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 16024644 15118125 15284455
KRAS HSP90AA1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 16024644 15118125 15284455
MYC HSP90AA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 28914785 12644583
SOCS1 JAK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 27144517 11133764 21508344
LCK JAK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11278738 17570479 16189514
LCK RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 7935389 8939988 16189514
SNW1 MAPK6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
MAPK6 TUBA1A â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
MYC RAF1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 28205554 17314511 28628118 9315742
MYC PEX14 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
MYC NRAS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
PEX14 PEX7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16189514 15798189 10212238
PPP2R2A RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15664191 23331499 16239230
HSP90AA1 HSPA4 â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
CCT3 CCT6A â—¼   CORRELATES + 0.9 0.9 CCLE 31978347
CCT2 CCT6A â—¼   CORRELATES + 0.9 0.9 CCLE 31978347
CCT4 CCT8 â—¼   CORRELATES + 0.9 0.9 CCLE 31978347
IGBP1 PPP4C â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
CCT3 CCT4 â—¼   CORRELATES + 0.9 0.9 CCLE 31978347
LRRK2 YWHAZ â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
CCT5 CCT6A â—¼   CORRELATES + 0.91 0.91 CCLE 31978347
CCT3 TRAF3IP3 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
CCT5 TRAF3IP3 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
CCT8 TRAF3IP3 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
TCP1 TRAF3IP3 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
COPS5 CUL3 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
HDAC3 HDAC5 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
ATF2 MAPK8 â—¼   PHYSICAL_INTERACTION 919.0 0.91 STRING 36370105
HSP90AA1 LRRK2 â—¼   PHYSICAL_INTERACTION 919.0 0.91 STRING 36370105
PPP2R2A PPP2R2B â—¼   CORRELATES + 0.91 0.91 CCLE 31978347
CCT4 TCP1 â—¼   CORRELATES + 0.92 0.92 CCLE 31978347
HCFC2 WDR5 â—¼   PHYSICAL_INTERACTION 925.0 0.92 STRING 36370105
NRAS RAF1 â—¼   PROXIMITY ✅ 0.93 0.93 mint 30194290
CCT4 CCT7 â—¼   CORRELATES + 0.93 0.93 CCLE 31978347
CCT7 TCP1 â—¼   CORRELATES + 0.93 0.93 CCLE 31978347
CCT8 TCP1 â—¼   CORRELATES + 0.93 0.93 CCLE 31978347
CCT3 TCP1 â—¼   CORRELATES + 0.93 0.93 CCLE 31978347
AKT1 STK4 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 19940129 17932490
BBS10 CCT6A â—¼   PHYSICAL_INTERACTION 940.0 0.94 STRING 36370105
PPP4C IGBP1 â—¼   PHYSICAL_INTERACTION ✅ 0.94 0.94 mint 27880917
WDR82 WDR5 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 20516061 23870121 27705803
BBS10 CCT4 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
BBS10 CCT8 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
BBS10 CCT7 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
TUBA1A TUBA1B â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
HSP90AA1 RAF1 â—¼   PHYSICAL_INTERACTION 942.0 0.94 STRING 36370105
CCT3 CCT8 â—¼   CORRELATES + 0.94 0.94 CCLE 31978347
FYN YES1 â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
NRAS RAF1 â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
CCT7 CCT8 â—¼   CORRELATES + 0.94 0.94 CCLE 31978347
AKT1 HSP90AA1 â—¼   PHYSICAL_INTERACTION 946.0 0.94 STRING 36370105
TUBA1B TUBB3 â—¼   CORRELATES + 0.94 0.94 CCLE 31978347
WDR5 WDR82 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
CCT2 CCT5 â—¼   CORRELATES + 0.95 0.95 CCLE 31978347
CCT3 CCT7 â—¼   CORRELATES + 0.95 0.95 CCLE 31978347
BBS10 CCT2 â—¼   PHYSICAL_INTERACTION 955.0 0.95 STRING 36370105
BBS10 CCT3 â—¼   PHYSICAL_INTERACTION 955.0 0.95 STRING 36370105
TRIB3 AKT1 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 31844113 12791994 30071535
YWHAZ RAF1 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 14688280 309620200 8006563
TUBA1A TUBB3 â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
KRAS RAF1 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
TUBA1B TUBB3 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
MAP2K5 MAP3K3 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
RAF1 YWHAZ â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
IGBP1 PPP6C â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
CCT2 CCT6A â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CCT3 CCT6A â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CCT4 CCT6A â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CCT6A CCT7 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CCT6A TCP1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CCT6A CCT8 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
METTL14 METTL3 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CDC5L SNW1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
PFDN1 VBP1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
PFDN1 PFDN2 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
CCT4 CCT8 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
CCT5 CCT6A â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PFDN2 VBP1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
CCT2 CCT3 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT2 CCT8 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT3 TCP1 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT3 CCT4 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT3 CCT7 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT4 CCT7 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT4 CCT5 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT7 CCT8 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT8 TCP1 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT2 CCT7 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT2 CCT4 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT2 CCT5 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT2 TCP1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT3 CCT5 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT3 CCT8 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT4 TCP1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT5 TCP1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT5 CCT7 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT5 CCT8 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT7 TCP1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CDK5 PRKN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 19399218 24486837 17327227 19050041 29899409
PRKN GPR37 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 11439185 14579121 12666095 15194120 12150907
PTPA AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 21159657 18039929 19216069 23109003 10026142 10995457 18042541 20452955 18559511 18588945 16680151 19405949 16227604 16406523
ILK AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 35.0 1.0 Omnipath 11546794 14500673 12176337 11445557 15899889 23840605 9736715 12149249 10592173 11313365 16189514 19460343 11278835 15212693 18772455 10226025 11825911
PDK1 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 12176337 15743829 12682057 11445557 15899889 12149249 10833263 15718470 11278835 10226025 11087733 14500673 16341064 19897009 9368760 24012393 11825911 9512493 9736715 11313365 9868760 15364915
TRIB3 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 30071535 12791994
HSP90AA1 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 19356729 18266962 10995457 25714412 16189514 12176997 12586360 15843522
PPP2R2A AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 18039929 19216069 18077353 19556239 19996169 10026142 10995457 18042541 20452955 18559511 18588945 16680151 20360384 16406523
TNK2 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 22322295 11394904 25678401 20333297 10652228
TBK1 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 21329883 21464307 21106850
PTK6 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 20606012 15994200 15539407
LRRK2 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 24916379 21658387
AKT1 RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 51.0 1.0 Omnipath 19197339 11971957 18767875 20230923 10576742 20068231 17570479 16189514 18669648 25241761 18691976 10576741 10618391 20688159 21745501 12087097 12801936 12048182 22798428 16854453 19058874 11997508
AKT1 BMI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22505453 23092893
AKT1 YWHAZ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 33.0 1.0 Omnipath 11756412 9705322 11923280 16697215 20398329 18372248 12865427 15071501 15808505 20138985 20214616 15883165 15169778 10949026 12861023 11715018 18636226 9812896 17680028 11956222 10722653 20832730 18570873 16376338 17052453
AKT1 STK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 21.0 1.0 Omnipath 22619175 19369195 19737514 19940129 17932490 23431053 11805089 24872389 23893242 17726016
AKT1 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 23331499 25241761 15104092 16362038 21071413 18988627 26297431 15048128
AKT1 IRAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 11976320
MYC APEX1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 14519204 11983916 12695333 11085504
KRAS ARAF â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 24937142 16537381 16364920 19727074 11325826 16508002 23360980 15467451 23993095 15258589
YWHAZ ARAF â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 19933840 20936779 25852190 20052757
ATF2 RAF1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 11274345 12738796 18039929 20506250
MAPK8 ATF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 64.0 1.0 Omnipath 17145710 11279118 17081983 20506250 12958075 9162092 19255142 8654373 20028971 15105425 17626013 12788955 11566021 15550563 10777545 23331499 7535770 15068801 21071413 17875713 9317150 16393692 15304344 18988627 7737130 26538579 21444723 602896 11896587 12110590 7824938 11274345 12874243 11971971 9399639 19436832 16533805 9670022 9029150 11865055 9207092 12804775 7737129 15212693 9405416
ZEB1 BMI1 â—¼   UP_REGULATES ✅ + 22.0 1.0 ACSN 10048576 16556862 17012742 17486063 19208835 19839049 19935649 20589835 20702634 20706219 21051859 21081489 21159887 21224848 22286765 22439866 225147423 22514743 22945800 24335145 28212565 9811054
MYC BMI1 â—¼   UP_REGULATES ✅ + 32.0 1.0 ACSN 11274345 11283614 12545156 14536078 15147722 15155580 15279786 17055429 17303408 17550342 17558397 17660363 17873522 18590585 18636226 20027199 20237412 20551172 20581311 20713526 20818389 21406394 21733352 2191300 21919891 22067385 23140366 23869868 25002027 28536364 7575488 9618481
HDAC3 BMI1 â—¼   UP_REGULATES ✅ + 22.0 1.0 ACSN 11283614 12545156 12668723 15151915 15155580 15465827 16232121 17055429 17508028 17550342 20027199 20713526 20818389 21234400 21733352 2191300 21919891 22370643 22796940 23140366 23869868 9618481
HDAC1 BMI1 â—¼   UP_REGULATES ✅ + 22.0 1.0 ACSN 11283614 12545156 12668723 15151915 15155580 15465827 16232121 17055429 17508028 17550342 20027199 20713526 20818389 21234400 21733352 2191300 21919891 22370643 22796940 23140366 23869868 9618481
CDK1 CDC20 â—¼   ENZYMATIC_REACTION ✅ 22.0 1.0 ACSN 12124778 14551205 14614141 15242590 15279786 15375219 15377654 15485915 15917306 16713580 16818604 17303408 17596790 17660363 18414028 18543256 18590585 18995830 19652693 19686080 7575488 9892021
MYC CDK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18802399 2237430 8065306 11085504
CDK1 MAPK6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20236090
FYN CDK5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 24872417 19901323 9038181 10896159 18691976 20506281 29063113 20068231 16497976 19413330 14757045 12372285
CDK5 HTT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 25799558 16782707 32668197 18691976 15911879 19413330 17611284
ERLIN2 KRAS â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 Reactome 19946327 11429702 11157491 18757403 21666749 21711248 18381441 19103595 21160078 9857065 20179196
ERLIN2 NRAS â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 Reactome 19946327 11429702 11157491 18757403 21666749 21711248 18381441 19103595 21160078 9857065 20179196
FYCO1 MAP1LC3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 27246247 26468287 20100911 20562859
FYCO1 MAP1LC3A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 27246247 26468287 20562859
ITGA4 FYN â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 ACSN 12626562 19161977 19454690 19487819 22470492 9003039 9456329 9763606 9973479
LCK FYN â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 9822663 15886116 10849438 12670394
HDAC1 HDAC3 â—¼   PHYSICAL_INTERACTION 22.0 1.0 ACSN 11283614 12545156 12668723 15151915 15155580 15465827 16232121 17055429 17508028 17550342 20027199 20713526 20818389 21234400 21733352 2191300 21919891 22370643 22796940 23140366 23869868 9618481
HDAC1 HDAC3 â—¼   SHARES_COMPLEX 22.0 1.0 ACSN 11283614 12545156 12668723 15151915 15155580 15465827 16232121 17055429 17508028 17550342 20027199 20713526 20818389 21234400 21733352 2191300 21919891 22370643 22796940 23140366 23869868 9618481
HDAC1 HDAC3 â—¼   UP_REGULATES ✅ + 22.0 1.0 ACSN 11283614 12545156 12668723 15151915 15155580 15465827 16232121 17055429 17508028 17550342 20027199 20713526 20818389 21234400 21733352 2191300 21919891 22370643 22796940 23140366 23869868 9618481
HDAC3 HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11302704 16189514 23213415 10944117
HDAC1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 21734722 17666529 15576399 22761862 22290435 19923891 20682799
PPP4C HDAC3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 15805470
HDAC6 HSP90AA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19158084 18591380 18266962
HSP90AA1 RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 25036637 19011619 16093354 8962087 18266962 8408024 23118896 22939624 24462205 16189514 17699868 20039095 16504566 20159553 17409432 16330544 15618521
MYC HSPA4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 1534087 14519204 1562593 10446203
TBK1 IKBKE â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 17599067 16177806 15210742 15210743 16306936 16127453 17468758 12702806 18353649 17327220 16858409
IKBKE TBK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 17599067 16177806 15210742 15210743 16306936 16127453 17468758 12702806 17327220 24622840 16858409
IKBKE IRF7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 16625202 25225665 9786932 15210742 22787218 10893229 26712804 16127453 12702806 16380379 15367631 12692549 17706453 16199137 16914100
IRAK1 IRF7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15767370 17457343 21903422
TBK1 IRF7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 16625202 17599067 9786932 15210742 22787218 26712804 16127453 12702806 15367631 12692549 16380379 17706453 16199137 16914100
VCAM1 ITGA4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 22623428 19738201 11751331
KRAS RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 53.0 1.0 Omnipath 10958680 12750173 9516156 12932319 9665134 10783161 8805624 1386920 1639773 8340422 8601312 19595761 23331499 16041367 21071413 8332195 9446616 10882715 25852190 10531446 1996324 19029954 8503013 16093354 19541618 23153539 16293107 1708096 19933846 26721396 11136732 10205168 20802526 31980649 7760835 18775988 8307946 12917261 11134016 20080631 8180183 1990291
KRAS MAP3K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 12228228 23331499 8649450 7744823
MAP3K3 MAP2K5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 12912994 23331499 25241761 16861740 19903815 14743216 11073940 16189514 17985933 24975362 10593883 25861671 12813044
MAP3K1 TNFRSF1B â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10465784 11274345 11668179 12048245 12738796 15170913 15592525 17462996 17496911 18641653 18855897 19392652 21133840 21232017 21614932 23850759 24378531 9379049 9582321
MAP3K1 TNFRSF1B â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10465784 11274345 11668179 12048245 12738796 15170913 15592525 17462996 17496911 18641653 18855897 19392652 21133840 21232017 21614932 23850759 24378531 9379049 9582321
MAP4K1 MAP3K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8824585 23331499 9003777
MAP3K1 MAPK8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 12228228 9405400 25241761 10465784 15757900 15299005 14500727 21152872 26538579
NOD2 MAPK8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17965022 15692051 17947236 17187069
MAPK8 STK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 27042197 20028971
MAPK8 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10601313 25714018
MAPK8 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 19651622 10551811 17081983 18767875 20068231 91332050 1651323 1748630 16713569 11243879 18669648 15210690
MAPK8 YWHAZ â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 22.0 1.0 Omnipath 18985696 25862939 15696159 11956222 19788416 21081103 15071501 18559254 7890696
MAPK8 PPM1J â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 20865152 18553930
MYC PDK1 â—¼   ENZYMATIC_REACTION ✅ 20.0 1.0 ACSN 11274345 11283613 11283614 11704864 16517405 16517406 17055429 17558397 17785433 17873522 20027199 20237412 20551172 20581311 20713526 21406394 2191300 22067385 25002027 28536364
SMAD3 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 15930298 20516082 14993291 17132729 16205635 25238097 11689553 17114344
MYC NME1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 18628958 12695333 14519204 16440314 11960382 11983916 18414489
MYC VHL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22286234 12695333
MYC SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23331499 11804592
MYC NME1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11960382 17093053
NRAS RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 46.0 1.0 Omnipath 9867809 12750173 12932319 9001246 9665134 8805624 1386920 1639773 8340422 8601312 19595761 23331499 21071413 8332195 10531446 10882715 7811320 1996324 18988627 21779497 8636091 8503013 7766599 16093354 19541618 8180183 1708096 19933846 32296183 9525741 8876196 11136732 10205168 21478863 7760835 18775988 12917261 11134016 18641128 20080631 9488663 1990291
PEX7 PEX14 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 21554508 24865970 19208625 26344566 8991089 27597759 18359941 26086376
WDR83 RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15118098 23331499
YWHAZ RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 46.0 1.0 Omnipath 17145710 7939632 7935795 16306228 9153224 20052757 8085158 8601312 16041367 7628630 11697890 9632690 25852190 9261098 16093354 12861023 15664191 22222486 19049963 10620507 17979178 10611249 14688280 10887173 20679480 12360521
RAF1 YWHAZ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 46.0 1.0 Omnipath 17145710 7939632 7935795 16306228 9153224 20052757 8085158 8601312 16041367 7628630 11697890 9632690 25852190 9261098 16093354 12861023 15664191 22222486 19049963 10620507 17979178 10611249 14688280 10887173 20679480 12360521
SMAD3 ZEB1 â—¼   DOWN_REGULATES ✅ - 22.0 1.0 ACSN 11074002 11279127 11792802 12702545 12809600 14976548 15265520 16179589 16713975 16831886 18768831 18832382 19208835 19597490 20731704 21042762 21317430 21614932 22331441 8515656 8893010 9389648
ZEB1 SOX2 â—¼   UP_REGULATES ✅ + 22.0 1.0 ACSN 10048576 16556862 17012742 17486063 19208835 19839049 19935649 20589835 20702634 20706219 21051859 21081489 21159887 21224848 22286765 22439866 225147423 22514743 22945800 24335145 28212565 9811054
DDB2 CDK18 â—¼   KO_UP_REGULATES ✅ + 1.16 1.16 PKG 28854368
DDB2 DDB2 â—¼   KO_DOWN_REGULATES ✅ - -5.71 5.7 PKG 28854368