Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
CCT2 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
CCT3 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
YWHAZ CCT4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
CCT8 CCT6A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
CCT6A YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
YWHAZ CCT7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
CCT7 PTAR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
CCT8 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
IRS1 EGFR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218056 16273093
YWHAZ EGFR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217069 15225635
BMX EGFR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218056 16273093
GRB10 EGFR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6547677 9506989
AREG EGFR â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 20430953 23010081
EGFR PTPN1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 9355745 6671413
EGFR YWHAZ â—¼   COLOCALIZATION 2.0 0.8 intact 5217069 15225635
FOXM1 FOS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16965535
DVL2 GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
PPP2CB GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15637081 16893902
PPP2R1A GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15637081 16893902
GRB10 GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
GRB2 RPS13 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 PPP2CA â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15637081 16893902
GRB2 RPS28 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 PLD2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6731738 16407827
GRB2 MYL6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 GAB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5212828 10913131
GRB2 RPS11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 TUBA4A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 LEPR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
GRB2 DVL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
MTOR HSF1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15760475 22768106
HSF1 CAMK2A â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15760475 11447121
HSF1 FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9341107 11026560
HSF1 HDAC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19793920
MDM2 ARRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5214648 11588219
FOS MDM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10348347 12173040
ARRB2 MDM2 â—¼   UBIQUITINATION ✅ 2.0 0.8 intact 5214648 11588219
RPS6KB1 MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20657550
MDM2 PPP2R2D â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 21460856
MDM2 PPP2R2C â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 21460856
YWHAZ MTOR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
MTOR EIF4EBP1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12150926 15809305
MTOR RRN3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23993916 25679014
CDC42 PAK1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 11278486 11804587
PAK1 MAP2K4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10385525 10791986
WEE1 SFN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15778465 5217604
SFN BRAF â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15778465 5217604
SFN IRS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15778465 5217604
TCP1 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
PCNA GAPDH â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7995081 20849852
GLI2 PCNA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14691458
GAPDH PCNA â—¼   COLOCALIZATION 2.0 0.8 intact 7995081 20849852
PCNA CCND3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16189514 7908906
NCBP2 NCBP1 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
AR AREG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23415714 20610535
CCND3 AREG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11469683 16713569
IGF1 SHC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8033892 7559507
SHC1 GAB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 10704825 5212298
IRS2 SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11505033 15705774
JAK1 SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 9670964
EGF SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19531499 17673906
ERBB4 SYK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218056 16273093
MAP2K7 MAP3K7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219344 17110930
ECSIT MAP3K7 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 10465784 25371197
IL2RA JAK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15178252 16477002
JAK1 CAMK2A â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15322115 11972023
LEPR JAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 16173077
JAK1 MAP3K5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19287004
TGFBR1 ITGA5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8410211 22940691
TGFBR1 CDC42 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 19114990
CASP8 CHUK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11002417
MYL6 CHUK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CHUK IRS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12351658
FGFR3 NCF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PPP2R2A KSR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 15664191
KSR1 YWHAZ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9115393 9858547
MAP3K5 MAP2K7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219344 17110930
MAP2K4 MAP3K5 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12189133 8974401
IRS2 YWHAB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
YWHAB WEE1 â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 10775038 5212493
YWHAB AFDN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
LRRK2 MAP2K7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19302196
LRRK2 MAP2K4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19302196
FGFR3 DVL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CDC42 RPS6KB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5214238 11438723
CDC42 KIF5A â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10913441 11689693
CDC42 EIF2AK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7738010 5220554
CDC42 RPS6KB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11438723
CD4 CD3D â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
EGF ERBB4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 7565730 8617750
IRS1 LEPR â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15316008 17565041
AR IRS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18521741 20610535
PTPN1 IRS1 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 intact 6732079 11579209
FOS WEE1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16000406 11500387
FOXC2 ITGB3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18579532 19372730
ITGB3 PTPN1 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 Reactome 16005629 16115959
ITGB3 PTPN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16115959
PRKCZ F11R â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17057644 5219258
YWHAZ PRKCZ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 10620507
YWHAG ARHGEF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
YWHAZ IRS2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
LEPR IRS2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15316008 17565041
IRS2 YWHAG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
AR IRS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19318566 20610535
TUBA4A S100A8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
CAMK2A GAPDH â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
YWHAZ GAPDH â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
AFDN YWHAG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
IL3RA YWHAG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
DRD1 YWHAG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CDK17 YWHAG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
YWHAE HDAC5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 10737771 5212359
PKN2 HDAC5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7710096 20188095
PPP2R2C PPP2R1B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
PPP2R2A PPP2R1B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8208439 17540176
PPP2R2A PPP2CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 1328247 19114990
PPP2R2A RPS6KB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16899564 10200280
PPP2CA CAMK2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7798931 9109540
PPP2CA EIF4EBP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16899564 16109716
ENSA PPP2R2D â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 21164013 21164014
AR YWHAH â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19996220 8009645
AR KDM4C â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16603238 18066052
AR KDM4C â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23698634 20610535
KDM4C AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17277772 29207681
MAGOH YWHAQ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
AFDN CTNNA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11907041
PRKCI F11R â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12953056 11447115
ERBB4 DLG3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5212340 10725395
BCAP31 SERTAD4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
YWHAZ CDK16 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12154078 8006101
YWHAZ CDK17 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
DSP YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
YWHAZ BCAP31 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
YWHAZ AFDN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
YWHAB YWHAG â—¼   PHYSICAL_INTERACTION 801.0 0.8 STRING 36370105
ALYREF NCBP1 â—¼   PHYSICAL_INTERACTION 805.0 0.8 STRING 36370105
IRS1 YWHAB â—¼   PHYSICAL_INTERACTION 806.0 0.8 STRING 36370105
CFTR YWHAG â—¼   PHYSICAL_INTERACTION 810.0 0.81 STRING 36370105
CFTR YWHAB â—¼   PHYSICAL_INTERACTION 812.0 0.81 STRING 36370105
CFTR YWHAZ â—¼   PHYSICAL_INTERACTION 812.0 0.81 STRING 36370105
PPP2R2C SERTAD4 â—¼   PHYSICAL_INTERACTION 817.0 0.81 STRING 36370105
ITGA5 ITGB3 â—¼   PHYSICAL_INTERACTION 818.0 0.81 STRING 36370105
LRRK2 ABCE1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31046837 24725412
IL3RA GRB2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17474147 7523859
LRRK2 PCNA â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31046837 24725412
SHC1 ACLY â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31980649 19380743
LRRK2 MYL6 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 20876399 24725412
LRRK2 YWHAE â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
PPME1 PPP2R2D â—¼   PHYSICAL_INTERACTION 829.0 0.83 STRING 36370105
CDK16 CDK17 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
EGFR GRB10 â—¼   PHYSICAL_INTERACTION 833.0 0.83 STRING 36370105
LRRK2 YWHAG â—¼   PHYSICAL_INTERACTION 833.0 0.83 STRING 36370105
GAB2 SHC1 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
ITGB6 TGFB1 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
CASP8 CUL3 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
GRB2 IRS2 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 7559579 22974441 9852124 21706016
CUL3 ACLY â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 21145461 27664236
DERL1 CFTR â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 18555783 16901789 16954204 26618866
RBM7 NCBP2 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 26382858 26496610
ERBB4 DLG3 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 12175853 10725395
PPP2R2D SERTAD4 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
EGFR GAPDH â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
LRRK2 CDC42 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 21048939 21454543
PRKCZ PRKCI â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 24375676
PPP2R1B PPP2R2B â—¼   PHYSICAL_INTERACTION 850.0 0.85 STRING 36370105
MAP2K4 MAP3K5 â—¼   PHYSICAL_INTERACTION 855.0 0.85 STRING 36370105
EGFR MAST1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 20029029 31980649
FGFR3 GRB2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 9045692 26344197
MLH1 PCNA â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 15225546 32814904 28439008
LRRK2 DVL2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 31046837 19625296
GAB2 SFN â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
CDCA4 PPP2R2A â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
AXIN1 PPP2CA â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
NCF1 PRKCZ â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
EGFR ARRB2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 24658140 25402006 31980649
GRB10 IRS1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 8621530 12783867
RBM7 SKIV2L2 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
EGFR YWHAZ â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
CHUK MAP3K7 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
IRS1 YWHAE â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
PPP2R2A SERTAD4 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
EGFR SFN â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
JAK1 GRB2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 11527382 8536716
PCNA CCND3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16189514 33961781 7908906
CASP8 CUL3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 19427028 23142077 25551360 28574503
YWHAE YWHAG â—¼   PHYSICAL_INTERACTION 879.0 0.88 STRING 36370105
YWHAE YWHAH â—¼   PHYSICAL_INTERACTION 879.0 0.88 STRING 36370105
PPP2R2A PPP2R2D â—¼   PHYSICAL_INTERACTION 879.0 0.88 STRING 36370105
MAP3K5 YWHAZ â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
YWHAB YWHAE â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
LRRK2 YWHAH â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
YWHAG YWHAZ â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
YWHAG YWHAH â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
PPP2R1B PPP2R2D â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
YWHAB YWHAH â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
YWHAH YWHAZ â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
ARRB2 MDM2 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
YWHAB YWHAZ â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
PPP2CA PPP2R2B â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
ITGB3 SHC1 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
EGFR PAK1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 31980649 24658140 12522133 25402006
EGFR ERBB4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 25140053 23153581 25315821 16061658 10572067
ERBB4 GRB2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16729043 22973453 24658140 25140053
GAB2 SHC1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 12135708 14982882 10704825 11782427
YWHAB BRAF â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 5217174 15324660
PPP2R1A CFTR â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 5217765 15936019
CFTR PPP2R1A â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 5217765 15936019
HDAC5 YWHAE â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
PPP2R1B PPP2CA â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 8392071 8286818
YWHAQ BRAF â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 5217174 15324660
HDAC5 YWHAQ â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
BRAF YWHAQ â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
EGFR PTPN1 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
PTPN1 EGFR â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 6671413 9355745
GRB10 EGFR â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 31980649 24658140 9506989 25402006 9006901
EGFR AREG â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16713569 28988771 10085134 8663535
PTPN1 EGFR â—¼   PHOSPHORYLATION ✅ 0.9 0.9 mint 6671413 9355745
PTPN1 EGFR â—¼   COLOCALIZATION ✅ 0.9 0.9 mint 6732094 9050838
EGFR PTPN1 â—¼   COLOCALIZATION ✅ 0.9 0.9 mint 25796184
EGFR JAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8524316 15284024
ITGB3 GRB2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 12005431 9566877 7997267
ERBB4 GRB2 â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
CDC42 GRB2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
IRS2 GRB2 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 19109239 7890616 9535722
JAK1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8536716 11527382
SFN MDM2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 8007833 17546054 1210540
AR MDM2 â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
MDM2 ARRB2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17984062 15878855 32450252 26545496 12488444 11588219 21988832 21466165 33649538 21389118 18544533 21081496 32828283 12538596
ERBB4 MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15985438
PPP2CA MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11983168
PPP2CB MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11983168
S100A9 NCF1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 23980663 22808130 21239714
HDAC5 SFN â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 8007093 15923258 0503275102
YWHAZ SFN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23840115 15161933
YWHAG SFN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15778465 15324660
SFN YWHAG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15778465 15324660
SFN YWHAZ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23840115 15161933
ERBB4 SHC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 9019162 22973453 24658140 16273093 16729043
JAK1 SYK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10825200
SYK PIK3AP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11163197
MAP2K7 MAP3K7 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 15837794 8533096 16186825
PPP2CA MAP3K7 â—¼   DEPHOSPHORYLATION ✅ 3.0 0.9 intact 608155200 17079228 8204431
AXIN1 DVL2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 10829020 29659741 23892894 21245303
PPP2CA CHUK â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 8209688 506093200 16126728
S100A8 NCF1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 23980663 22808130 21239714
NCF1 PRKCZ â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 12056906 27558335 19372727
YWHAB PRKCZ â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
YWHAG YWHAB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17085597 15324660
YWHAB YWHAG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17085597 15324660
CDC42 MAP2K7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9574518 9305638 23109003
MAP2K7 IRS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17360977
EIF2AK2 IRS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 30071259 20685959 28779021
AR WEE1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 20610535 16281084
BDNF NGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19908279 25354496 9775403
YWHAE GAPDH â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
YWHAG BRAF â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 5217174 15324660
YWHAE YWHAZ â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
PPP2R1A PPP2CB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15936019 16039140
PPP2CB RPS6KB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 2826472 11124802 10200280
AR PTPN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22282656 20610535
LRRK2 YWHAQ â—¼   PHYSICAL_INTERACTION 907.0 0.9 STRING 36370105
YWHAZ YWHAE â—¼   PHYSICAL_INTERACTION ✅ 0.91 0.91 mint 20618440 7899808
PPP2R2A PPP2CA â—¼   PHYSICAL_INTERACTION ✅ 0.91 0.91 mint 20711181 8288198
LRRK2 YWHAZ â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
FLT4 SHC1 â—¼   PHYSICAL_INTERACTION 911.0 0.91 STRING 36370105
PPME1 PPP2CA â—¼   DEMETHYLATION ✅ - 0.91 0.91 Signor 18394995
GRB2 IRS1 â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
PPME1 PPP2CB â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
PPP2CB PPP2R2B â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
ERBB4 SHC1 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
PPP2R1A PPP2CB â—¼   PHYSICAL_INTERACTION ✅ 0.92 0.92 mint 5217765 15936019
YWHAZ BRAF â—¼   PHYSICAL_INTERACTION ✅ 0.92 0.92 mint 5217040 15161933
EGFR GRB2 â—¼   PHOSPHORYLATION 0.92 0.92 Signor 11726515
PAK1 CDC42 â—¼   PHYSICAL_INTERACTION ✅ 0.94 0.94 mint 5220560 7744004
ABCE1 RPS11 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
ABCE1 RPS28 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
PPP2R1A PPP2R2B â—¼   PHYSICAL_INTERACTION 944.0 0.94 STRING 36370105
ABCE1 RPS13 â—¼   PHYSICAL_INTERACTION 949.0 0.95 STRING 36370105
JAK1 IRS1 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 11162588 7499365 9492017
PPP2R2A PPP2R1A â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 17245430 5219546
S100A8 S100A9 â—¼   PHYSICAL_INTERACTION 951.0 0.95 STRING 36370105
PPP2CB PPP2R2D â—¼   PHYSICAL_INTERACTION 955.0 0.95 STRING 36370105
NCBP2 NCBP1 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 24981860
RPS6KB1 MTOR â—¼   PHOSPHORYLATION ✅ - 0.96 0.96 Signor 15905173
MTOR RPS6KB1 â—¼   PHOSPHORYLATION ✅ + 0.96 0.96 Signor 12782654
PPP2CB PPP2R1B â—¼   PHYSICAL_INTERACTION 960.0 0.96 STRING 36370105
PPP2R1B PPP2R2A â—¼   PHYSICAL_INTERACTION 960.0 0.96 STRING 36370105
LRRK2 SFN â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
EGFR EGF â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 8145580 21439278
SHC1 EGFR â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 7518560 8034616 31980649 23956138 9544989 8610109 7542744 25402006 16729043 8665853 15657067 9742218 24797263 10049786 12577067 9756944 23799367 25187647 20935677 10766863 18271526 11408594 7506413 10635327 10595738 24189400 19531499 7542991 20473329 24430869 8662998 9020193 8887653 16273093 25754235 9388490 31959764 26551075 16713569 22973453 24658140 11196191 28065597 20067773 8810340 21278788 30544639 9130710 11370743
EGFR EGF â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 16274239 25241761 10085134 11684674 28988771 22729867 18271526 30083275 10788520 23597562 19531499 26280537 8663535 25453753 21822280 12297050 2790960 21439278 12093292 12620237 10970856 18427122 25080504 17697999 9135143 15620700
EGFR GRB2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 19254954 7518560 31980649 9416834 7592693 23956138 14679214 10085134 7510700 27059931 21706016 25402006 16799092 16729043 8665853 15657067 24797263 12577067 8810325 7650032 11960376 23799367 25187647 8626525 10026169 19289468 18271526 21278786 7506413 17971399 8940013 20124286 11726515 9886492 10595738 24189400 9020117 19531499 20473329 9020193 8662998 8647858 1322798 8887653 10229072 16273093 25754235 31959764 11370743 16713569 21596750 9685397 24658140 31985874 22973453 11896612 20067773 17242169 19836242 8810340 21278788 30544639 7527043 9050991 11408594 8621459
SHC1 GRB2 â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 8940013 6169950
IRS1 GRB2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 7488107 8388384 7486683 8810325 22974441 21706016 8491186 7629070 12173038 8536716
GAB2 GRB2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 25416956 31980649 21706016 10068651 16371368 10391903 32296183 15143164 10913131 19523899 19172738 11782427 19380743 11882361 9660791 16253990 33961781 20936779
PAK1 CDC42 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 9535855 11157984 21029865 16678097 19596003 23455922 9705280 31871319 25150978 12879077 12606577 10360579 31478661 10684602 8107774 21048135 23175184 18057010 10802735 21167153 15548653 12650940 18426980 7744004 20936779 24276241
NCBP2 NCBP1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 16189514 23665581 9933612 26382858 31467278 11545740 22365833 26496610 29395067 12374755 26264872 7478990 19668212 22939629 29997244 32814053 29101316 24981860 31448526 17190602 12434151 26344197
GAB2 GRB2 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
BRAF YWHAZ â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
SHC1 EGFR â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 16729043 5218694
GRB2 EGFR â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 16729043 5218694
EGF EGFR â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
EIF4EBP1 MTOR â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
AXIN1 DVL2 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
SHC1 GRB2 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 12485888 21725358 31980649 9126968 7514169 7744881 8235613 11453982 8662733 8491186 7629070 8940013 10570290 8112292 12213123 11302736 8662998 8195171 7597091 8810340 32062451 9129019 16371368 12149229 10049786 8626525 7650032 8950973 9488479 24189400 15812354 12441060 19380743 26551075 22057045 10477741 28690151 16713569 7516467 9733714 11827484 11964172 7537740 16520382 9019162 8663178 9797459 9032244 12577067 9927207 7524086 8995379 9886492 8294403 7559490 9434624 11792427 7798267 8621719 9541596 15688026 12898421 33961781 11370743 25416956 9544989 22974441 8939605 21706016 9083103 7535773 11505033 9175774 24430869 10080542 9020193 9045692 10356320 15888547 9254595 8561895 11707405 8647288
RBM7 ZCCHC8 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
RPS11 RPS28 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
CCT6A PPP2R2C â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
CCT7 PPP2R2C â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
CCT8 PPP2R2C â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
CCT8 PPP2CA â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
CCT8 PPP2CB â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
MTOR RPS6KB1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
PPP2R1A PPP2R1B â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
CCT2 PPP2CB â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CCT2 PPP2R2C â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CCT2 PPP2CA â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CCT3 PPP2CA â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CCT3 PPP2R2C â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CCT3 PPP2CB â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CCT4 PPP2R2C â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CCT4 PPP2CA â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CCT4 PPP2CB â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CCT5 PPP2CB â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CCT5 PPP2R2C â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CCT5 PPP2CA â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CCT6A PPP2CB â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CCT6A PPP2CA â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CCT7 PPP2CB â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CCT7 PPP2CA â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
PPP2CA TCP1 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
PPP2CB TCP1 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
PPP2R2C TCP1 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
PPME1 PPP2R1A â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CCT2 CCT6A â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CCT3 CCT6A â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CCT4 CCT6A â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CCT6A TCP1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CCT6A CCT7 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CCT6A CCT8 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
GNB3 GNG12 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
GNB3 GNG7 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
PPME1 PPP2CA â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
EGFR SHC1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
CDC42 PAK1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
NCBP1 NCBP2 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
CCT4 CCT8 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
CCT5 CCT6A â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PPP2R1B PPP2R2C â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PPP2R1A PPP2R2C â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PPP2R1A PPP2R2D â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PPP2R1A PPP2R2A â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PPP2CA PPP2R2C â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPS13 RPS28 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
CCT2 CCT8 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT2 CCT3 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT3 CCT4 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT3 TCP1 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT3 CCT7 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT4 CCT5 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT4 CCT7 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT7 CCT8 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT8 TCP1 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
PPP2CB PPP2R2A â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
PPP2CA PPP2R2A â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
PPP2CA PPP2R2D â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPS11 RPS13 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT2 CCT7 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT2 TCP1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT2 CCT4 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT2 CCT5 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT3 CCT5 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT3 CCT8 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT4 TCP1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT5 TCP1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT5 CCT8 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT5 CCT7 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT7 TCP1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
EGFR GRB2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PPP2CB PPP2R1A â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PPP2CA PPP2R1B â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PPP2CA PPP2R1A â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
AR ABCE1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20610535
EGF EGFR â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 ACSN 15003992 15175028 15466195 15958574 18423981 19631971 20430953 21098712 8101258
EGFR SHC1 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 10404636 20430953 23010081 25987127 28513565
EGFR GRB2 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 10404636 20430953 23010081 25987127 28513565
AR EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 15305378 19318561 21613411 19258514 15650253 17242169 18692155 15288768 11556855 20610535
PPP2CA EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18039929 16680151 10995457 18042541 18588945
CAMK2A EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 33.0 1.0 Omnipath 17389395 17081983 3138233 20166139 10347170 15901825 16799092 18691976 8226933 20068231 1309762 7805884 92065884 1956339 7505275 18669648 15302935
AREG EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 23331499 23762360 21071413 10209155 10085134 29045902 2466334 20513444 16713569
TGFB1 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20953304 32103204 19132220 28943431
AR EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 18358509 12534934 22260327 15288768 18951974
EGF EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 131.0 1.0 Omnipath 17145710 17081983 21822280 20813200 23613900 9135143 25453753 21303971 10209155 26821125 12297050 27387652 25241761 30083275 12093292 30197274 21649524 19531499 18762250 16729043 26921391 17697999 17575160 21722395 12620237 19129184 10788520 23331499 3494473 15620700 14568001 15958209 24096486 18253097 16843263 18320059 21532939 10085134 22260327 15708576 26280537 23912460 21858221 11116185 10970856 27462018 18427122 25080504 20953304 19135477 11684674 8639530 27564112 18270696 2790960 17971399 23185569 19895983 28988771 29617357 23597562 19531623 23950932 21071413 8663535 6289330 16274239 17563729 21439278 20458382 22216880 18271526 12771140 21311755 24709886 25366117 12648462 21107857
EGFR PTPN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 41.0 1.0 Omnipath 25796184 31980649 8621392 12573287 18253097 11106648 11506178 24658140 7540771 9050838 9355745 15982634 25402006 10889023 7693694 8999839
EGFR GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 109.0 1.0 Omnipath 9544989 10595738 23956138 27059931 10026169 16273093 11726515 24697349 21596750 19289468 7518560 21706016 23799367 9050991 16317285 16713569 25402006 11370743 24797263 8647858 8887653 9416834 21278786 16799092 8662998 10229072 11896612 7592693 19509291 8810325 24189400 19836242 11960376 7506413 18271526 15657067 10085134 24658140 17242169 7510700 8940013 7650032 8810340 11084343 12577067 7527043 31980649 11408594 19531499 20124286 23178716 9886492 23181695 9020117 8479540 14679214 12648464 1322798 17991782 16729043 17971399
EGFR SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 78.0 1.0 Omnipath 9544989 8808684 10595738 23956138 9388490 11350724 16273093 7542991 7681824 7518560 9710588 23799367 16713569 25402006 11370743 24797263 9742218 20935677 8887653 8034616 23331499 8662998 7542744 10049786 28065597 9130710 10635327 24189400 7506413 18271526 15657067 24658140 8810340 12577067 11196191 10766863 23178716 31980649 35384245 11408594 19531499 9756944 26551075 1623525 15951569 16729043 17956904
EGFR PLD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 9837959 20647543 20176813
EGFR PCNA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 21220489 24655521 23542172 29140271 28157503 26725162 22238610 25825764 17115032 26719139 28102297 22692198 28666590 25073158 20670598 20587074 23593472 25675097
SYK GRB2 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 12456653 9341187 9705962 19372136 11071869 11449366 11909947 9697839 21822214
IRS1 GRB2 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 8316835 8810325 9832424 8621421 8530377 9852124 9003010
GRB2 SYK â—¼   PHYSICAL_INTERACTION 71.0 1.0 ACSN 10022831 10086337 10358164 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11907067 11960372 12175651 12393695 12524384 12629515 12640133 13678960 14568985 15099563 15111329 15501236 15520864 15536084 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17101731 17496910 17673906 17883421 19414323 19449109 19909365 20150200015 21149606 21372296 21378271 21910624 22064427 22461508 23390297 23609447 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8189062 8226994 8551221 8837607 9000133 9157999 9295024 9314552 9396765 9570538 9632805 9753319 9763615
GRB2 FLT4 â—¼   PHYSICAL_INTERACTION 32.0 1.0 ACSN 10086337 10567412 10811803 10849428 10982827 11335727 11447289 11449354 11532940 11777939 12175651 12393695 12640133 15308668 15567848 15574420 16000375 16076871 16530705 16582911 16887996 17496910 17673906 18835194 19449109 19454690 22064427 22464172 24217602 25922287 26552706 8551221
GRB2 BRAF â—¼   PHYSICAL_INTERACTION 48.0 1.0 ACSN 10086337 10567412 10811803 10843677 10982827 11023813 11034387 11062502 11385609 11447289 11777939 11907067 12040186 12175651 12419216 12640133 12782630 14585353 14764585 15169888 15536084 15547943 15567848 15574420 15735649 15863030 16102570 16227978 16488589 16582911 16887996 17178906 17395718 17496910 17613518 17673906 19449109 19541618 19565474 19568798 19615955 21102635 22435554 24027568 26552706 7510700 8551221 9510155
GRB2 ANGPT1 â—¼   PHYSICAL_INTERACTION 24.0 1.0 ACSN 10086337 10567412 10811803 10849428 10982827 11283723 11447289 11449354 11777939 12175651 12393695 12640133 15520864 15567848 15574420 16076871 16582911 16887996 17496910 17673906 19223473 19449109 26552706 8551221
GRB2 KSR1 â—¼   PHYSICAL_INTERACTION 53.0 1.0 ACSN 10086337 10567412 10811803 10843677 10982827 11023813 11034387 11062502 11274345 11385609 11447289 11777939 11907067 12040186 12175651 12419216 12640133 12782630 14585353 14724641 14764585 15169888 15173823 15536084 15547943 15567848 15574420 15735649 15863030 16102570 16227978 16488589 16582911 16887996 17178906 17395718 17496910 17613518 17673906 19289794 19449109 19541618 19565474 19568798 19615955 21102635 22435554 24027568 26552706 7510700 8551221 8929532 9510155
GRB2 SHC1 â—¼   PHYSICAL_INTERACTION 69.0 1.0 ACSN 10022831 10086337 10358164 10567412 10811803 10849428 10982827 11166270 11283723 11335727 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15308668 15501236 15520864 15567848 15573129 15574420 15863030 16000375 16002046 16076871 16102570 16212621 16530705 16572188 16582911 16887996 17086423 17496910 17673906 17883421 18835194 19223473 19414323 19449109 19454690 19909365 21372296 21378271 22064427 22461508 22464172 23390297 23896411 24027568 24217602 24346288 24670066 25922287 26201938 26552706 7510700 8551221 8837607 9157999 9570538 9753319 9763606
GRB2 SHC1 â—¼   PROTEIN_INTERACTION 69.0 1.0 ACSN 10022831 10086337 10358164 10567412 10811803 10849428 10982827 11166270 11283723 11335727 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15308668 15501236 15520864 15567848 15573129 15574420 15863030 16000375 16002046 16076871 16102570 16212621 16530705 16572188 16582911 16887996 17086423 17496910 17673906 17883421 18835194 19223473 19414323 19449109 19454690 19909365 21372296 21378271 22064427 22461508 22464172 23390297 23896411 24027568 24217602 24346288 24670066 25922287 26201938 26552706 7510700 8551221 8837607 9157999 9570538 9753319 9763606
GRB2 SYK â—¼   SHARES_COMPLEX 71.0 1.0 ACSN 10022831 10086337 10358164 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11907067 11960372 12175651 12393695 12524384 12629515 12640133 13678960 14568985 15099563 15111329 15501236 15520864 15536084 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17101731 17496910 17673906 17883421 19414323 19449109 19909365 20150200015 21149606 21372296 21378271 21910624 22064427 22461508 23390297 23609447 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8189062 8226994 8551221 8837607 9000133 9157999 9295024 9314552 9396765 9570538 9632805 9753319 9763615
GRB2 ANGPT1 â—¼   SHARES_COMPLEX 24.0 1.0 ACSN 10086337 10567412 10811803 10849428 10982827 11283723 11447289 11449354 11777939 12175651 12393695 12640133 15520864 15567848 15574420 16076871 16582911 16887996 17496910 17673906 19223473 19449109 26552706 8551221
GRB2 KSR1 â—¼   SHARES_COMPLEX 53.0 1.0 ACSN 10086337 10567412 10811803 10843677 10982827 11023813 11034387 11062502 11274345 11385609 11447289 11777939 11907067 12040186 12175651 12419216 12640133 12782630 14585353 14724641 14764585 15169888 15173823 15536084 15547943 15567848 15574420 15735649 15863030 16102570 16227978 16488589 16582911 16887996 17178906 17395718 17496910 17613518 17673906 19289794 19449109 19541618 19565474 19568798 19615955 21102635 22435554 24027568 26552706 7510700 8551221 8929532 9510155
GRB2 FLT4 â—¼   SHARES_COMPLEX 32.0 1.0 ACSN 10086337 10567412 10811803 10849428 10982827 11335727 11447289 11449354 11532940 11777939 12175651 12393695 12640133 15308668 15567848 15574420 16000375 16076871 16530705 16582911 16887996 17496910 17673906 18835194 19449109 19454690 22064427 22464172 24217602 25922287 26552706 8551221
GRB2 BRAF â—¼   SHARES_COMPLEX 48.0 1.0 ACSN 10086337 10567412 10811803 10843677 10982827 11023813 11034387 11062502 11385609 11447289 11777939 11907067 12040186 12175651 12419216 12640133 12782630 14585353 14764585 15169888 15536084 15547943 15567848 15574420 15735649 15863030 16102570 16227978 16488589 16582911 16887996 17178906 17395718 17496910 17613518 17673906 19449109 19541618 19565474 19568798 19615955 21102635 22435554 24027568 26552706 7510700 8551221 9510155
FOS GRB2 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 11274345 12738796 15067049 16393692 16394015 18039929 19667062 21385848 22634314 23430059 9064320
IRS1 GRB2 â—¼   ENZYMATIC_REACTION ✅ 12.0 1.0 ACSN 10086337 10826997 12175651 12444011 12767520 16931767 17604717 19030972 21540285 22465479 24036369 8621421
GRB2 FLT4 â—¼   ENZYMATIC_REACTION ✅ 32.0 1.0 ACSN 10086337 10567412 10811803 10849428 10982827 11335727 11447289 11449354 11532940 11777939 12175651 12393695 12640133 15308668 15567848 15574420 16000375 16076871 16530705 16582911 16887996 17496910 17673906 18835194 19449109 19454690 22064427 22464172 24217602 25922287 26552706 8551221
GRB2 KSR1 â—¼   ENZYMATIC_REACTION ✅ 53.0 1.0 ACSN 10086337 10567412 10811803 10843677 10982827 11023813 11034387 11062502 11274345 11385609 11447289 11777939 11907067 12040186 12175651 12419216 12640133 12782630 14585353 14724641 14764585 15169888 15173823 15536084 15547943 15567848 15574420 15735649 15863030 16102570 16227978 16488589 16582911 16887996 17178906 17395718 17496910 17613518 17673906 19289794 19449109 19541618 19565474 19568798 19615955 21102635 22435554 24027568 26552706 7510700 8551221 8929532 9510155
GRB2 SYK â—¼   ENZYMATIC_REACTION ✅ 71.0 1.0 ACSN 10022831 10086337 10358164 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11907067 11960372 12175651 12393695 12524384 12629515 12640133 13678960 14568985 15099563 15111329 15501236 15520864 15536084 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17101731 17496910 17673906 17883421 19414323 19449109 19909365 20150200015 21149606 21372296 21378271 21910624 22064427 22461508 23390297 23609447 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8189062 8226994 8551221 8837607 9000133 9157999 9295024 9314552 9396765 9570538 9632805 9753319 9763615
GRB2 GAB2 â—¼   ENZYMATIC_REACTION ✅ 25.0 1.0 ACSN 10086337 10358164 10567412 10811803 10849428 10982827 11447289 11449354 11777939 12175651 12393695 12640133 15567848 15574420 16076871 16212621 16582911 16887996 17496910 17673906 19449109 19909365 26552706 8551221 9763606
GRB2 SHC1 â—¼   ENZYMATIC_REACTION ✅ 69.0 1.0 ACSN 10022831 10086337 10358164 10567412 10811803 10849428 10982827 11166270 11283723 11335727 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15308668 15501236 15520864 15567848 15573129 15574420 15863030 16000375 16002046 16076871 16102570 16212621 16530705 16572188 16582911 16887996 17086423 17496910 17673906 17883421 18835194 19223473 19414323 19449109 19454690 19909365 21372296 21378271 22064427 22461508 22464172 23390297 23896411 24027568 24217602 24346288 24670066 25922287 26201938 26552706 7510700 8551221 8837607 9157999 9570538 9753319 9763606
GRB2 MAP2K4 â—¼   ENZYMATIC_REACTION ✅ 32.0 1.0 ACSN 10086337 10567412 10811803 10982827 11274345 11447289 11756498 11777939 12040186 12175651 12640133 12738796 14585353 15567848 15574420 15863030 16102570 16582911 16887996 17496910 17673906 18000759 18855897 19151919 19449109 19568798 21614932 24027568 26552706 27331412 7510700 8551221
GRB2 MAP2K7 â—¼   ENZYMATIC_REACTION ✅ 32.0 1.0 ACSN 10086337 10567412 10811803 10982827 11274345 11447289 11756498 11777939 12040186 12175651 12640133 12738796 14585353 15567848 15574420 15863030 16102570 16582911 16887996 17496910 17673906 18000759 18855897 19151919 19449109 19568798 21614932 24027568 26552706 27331412 7510700 8551221
GRB2 ANGPT1 â—¼   ENZYMATIC_REACTION ✅ 24.0 1.0 ACSN 10086337 10567412 10811803 10849428 10982827 11283723 11447289 11449354 11777939 12175651 12393695 12640133 15520864 15567848 15574420 16076871 16582911 16887996 17496910 17673906 19223473 19449109 26552706 8551221
SHC1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 198.0 1.0 Omnipath 8808684 9083103 8551221 9126968 8621483 25416956 9252386 8524223 7535773 8662998 11302736 11827484 8995379 9541596 9175774 10207047 7717978 17673906 7744881 11505033 10523831 24189400 9927207 7650032 8810340 9045692 23178716 19531499 15812354 9129019 10356320 12485888 9461587 8114695 7514169 9566877 8939605 16371368 15341520 7529871 10891441 10749687 7524086 26645482 8491186 10592173 10049786 9171350 11707404 7537740 15688026 8663178 19380743 11782427 9544989 16436051 9434624 16713569 21725358 11964172 17314098 11792427 8195171 1465135 12213123 8647288 12955078 10477741 11707405 12577067 9199344 10080542 8112292 7760801 10570290 11997181 7798267 16520382 10961885 8950973 21706016 9448048 8662733 11370743 8051109 9733714 8621475 9254595 8294403 10748054 8621719 8940013 12441060 22057045 7505797 24737791 20697350 9886492 18174162 18273058 8235613 7963520 7523859
FLT4 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9927207 8662748 7675451 7970715
ERBB4 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 24658140 16829981 16729043 12731860 25140053
IRS1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 8265614 7862167 11788580 8388384 8491186 8536716 7488107 7486683 10358772 10592173 8196603 12173038 12679424 8114695 11259577 8810325
EGF GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17081983 19531499 17673906 10973965
SYK GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11964172 16189514 22267732 10747947
IRS2 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 7559579 11788580 10358772 11305324 9852124
GRB2 PAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12522133
GRB2 GAB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 37.0 1.0 Omnipath 17145710 16371368 25416956 21706016 15143164 10391903 19172738 10913131 11027663 9973481 10973965 20936779 10068651 11882361 32296183 16199887 24737791 15010462 19523899 16253990 19380743 31515488 11782427
CAMK2A HSF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 23587601 26361762 25380824 24746225 22496356 28415561 15760475 11447121 25963659 33177089 15302935 26193369
CSNK1D MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 22.0 1.0 Omnipath 26294215 11850850 12167711 16055726 15610030 15688025 15703839 20708156 28049764 33618712 15024078 19630168 26636645 19008219 27617579
MDM2 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 17974989 26411689 27835608 26973243 15640443 12145204
PCNA MLH1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 20154325 22118461 11274057 23840062
CHUK MTOR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18519641 24990947 18490760 27027448
MTOR RPS6KB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 111.0 1.0 Omnipath 25062042 17510057 17081983 15208671 22873724 16922504 23077579 12087098 28270148 16286006 15896331 25356520 17664694 21790669 26919095 26313911 21561857 10567431 16099428 21977024 14679009 11940578 15899889 15388791 12829246 21980324 22751450 12604610 9465032 20068231 10601311 28122439 19302577 21602892 15718470 15631631 23273915 18669648 21307646 10579915 23261705 20169205 25936802 25486097 24411482 12586835 23342114 15809305 14560963 22472346 11279232 15760907 9271440 27856330 12370290 23486913 12782654 11914378 24795562 19877273 28242756 11500364 26698305 14993219 20459645 23029019 16964243 15212693 25505994
MTOR GRB10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15952796 21659605 21659604
MTOR IRS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 22570710 15952059 19561084 21282364 25973388 14769130 11287630 9335553 17698034 20863384
MTOR EIF4EBP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 132.0 1.0 Omnipath 17510057 17081983 11691836 22873724 18767875 16824195 19147279 23077579 24303063 28272965 19690332 11438723 12665511 17043358 19413330 10405182 20670887 19209957 19664995 15070431 9826548 12747827 10942774 16242075 9092573 12604610 20068231 9465032 21190521 23360111 17991864 25686248 9204908 11777913 18669648 12150926 8083223 20537536 12105188 17386266 24205284 17517883 26985829 19291795 23972597 16288292 17487921 8895571 17287340 9405468 20227039 12588975 12370290 17717968 23486913 19651622 10779345 26255626 18220336 16404421 18283322 10364159 15066126 12912989 17693255 15767663
SHC1 PAK1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 19124833 9989831 15548136 19574218
PPP2CA PAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 9873003 18586681 10322434
PPP2CB PAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 18586681 10322434
CDC42 PAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 60.0 1.0 Omnipath 17145710 810774 10360579 21167153 8107774 10559936 9705280 12650940 16678097 23331499 21029865 10684602 18057010 15020669 21070974 11340065 21048135 15003621 20936779 10934474 11413130 15788770 15713627 9535855 23109003 11950587 19628037 7744004 12879077 12606577 24276241 10224076 19596003 8973630 19812368 11248548 10802735 18719708 10613909 10461188 23455922
PAK1 ARHGEF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 21.0 1.0 Omnipath 22072711 17488622 14970201 19667072 19690332 29036929 24352660 28096473 20406887 18669648
PAK1 NCF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12855698 7618083 16099876 10559253 18160398
PAK1 BRAF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17192257 15710605 10205168 25733387
S100A9 S100A8 â—¼   PHYSICAL_INTERACTION 5.0 1.0 ACSN 12645005 18802069 18809714 19732719 23248262
S100A9 S100A8 â—¼   SHARES_COMPLEX 5.0 1.0 ACSN 12645005 18802069 18809714 19732719 23248262
SFN YWHAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21827211 12657644 12426317 15071501
TGFBR1 CCL3 â—¼   DOWN_REGULATES ✅ - 44.0 1.0 ACSN 11279127 11792802 12809600 14557817 15003992 15099563 15265520 15653932 16127449 16424049 16474430 16572188 17070508 17404308 17768418 17934056 17979848 18423981 18490733 19038247 19109155 19732719 19747910 20060931 20519943 20538542 20616810 20644162 21041659 21098712 21278795 21372296 21614932 22703233 22874531 23034983 23784029 24132110 24336330 26201938 26966341 2871107 7594497 8515656
FGF21 FGFR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16597617 25772309
FGFR3 SHC1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 9045692 9480847 18840094 7559490
ITGA5 SHC1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 19342448 21844907 10714768 8598224
SHC1 ANGPT1 â—¼   PHYSICAL_INTERACTION 24.0 1.0 ACSN 10086337 10567412 10811803 10849428 10982827 11283723 11447289 11449354 11777939 12175651 12393695 12640133 15520864 15567848 15574420 16076871 16582911 16887996 17496910 17673906 19223473 19449109 26552706 8551221
SHC1 SYK â—¼   PHYSICAL_INTERACTION 71.0 1.0 ACSN 10022831 10086337 10358164 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11907067 11960372 12175651 12393695 12524384 12629515 12640133 13678960 14568985 15099563 15111329 15501236 15520864 15536084 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17101731 17496910 17673906 17883421 19414323 19449109 19909365 20150200015 21149606 21372296 21378271 21910624 22064427 22461508 23390297 23609447 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8189062 8226994 8551221 8837607 9000133 9157999 9295024 9314552 9396765 9570538 9632805 9753319 9763615
SHC1 FLT4 â—¼   PHYSICAL_INTERACTION 32.0 1.0 ACSN 10086337 10567412 10811803 10849428 10982827 11335727 11447289 11449354 11532940 11777939 12175651 12393695 12640133 15308668 15567848 15574420 16000375 16076871 16530705 16582911 16887996 17496910 17673906 18835194 19449109 19454690 22064427 22464172 24217602 25922287 26552706 8551221
SHC1 ANGPT1 â—¼   SHARES_COMPLEX 24.0 1.0 ACSN 10086337 10567412 10811803 10849428 10982827 11283723 11447289 11449354 11777939 12175651 12393695 12640133 15520864 15567848 15574420 16076871 16582911 16887996 17496910 17673906 19223473 19449109 26552706 8551221
SHC1 FLT4 â—¼   SHARES_COMPLEX 32.0 1.0 ACSN 10086337 10567412 10811803 10849428 10982827 11335727 11447289 11449354 11532940 11777939 12175651 12393695 12640133 15308668 15567848 15574420 16000375 16076871 16530705 16582911 16887996 17496910 17673906 18835194 19449109 19454690 22064427 22464172 24217602 25922287 26552706 8551221
SHC1 SYK â—¼   SHARES_COMPLEX 71.0 1.0 ACSN 10022831 10086337 10358164 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11907067 11960372 12175651 12393695 12524384 12629515 12640133 13678960 14568985 15099563 15111329 15501236 15520864 15536084 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17101731 17496910 17673906 17883421 19414323 19449109 19909365 20150200015 21149606 21372296 21378271 21910624 22064427 22461508 23390297 23609447 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8189062 8226994 8551221 8837607 9000133 9157999 9295024 9314552 9396765 9570538 9632805 9753319 9763615
SHC1 GAB2 â—¼   ENZYMATIC_REACTION ✅ 25.0 1.0 ACSN 10086337 10358164 10567412 10811803 10849428 10982827 11447289 11449354 11777939 12175651 12393695 12640133 15567848 15574420 16076871 16212621 16582911 16887996 17496910 17673906 19449109 19909365 26552706 8551221 9763606
SHC1 SYK â—¼   ENZYMATIC_REACTION ✅ 71.0 1.0 ACSN 10022831 10086337 10358164 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11907067 11960372 12175651 12393695 12524384 12629515 12640133 13678960 14568985 15099563 15111329 15501236 15520864 15536084 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17101731 17496910 17673906 17883421 19414323 19449109 19909365 20150200015 21149606 21372296 21378271 21910624 22064427 22461508 23390297 23609447 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8189062 8226994 8551221 8837607 9000133 9157999 9295024 9314552 9396765 9570538 9632805 9753319 9763615
SHC1 FLT4 â—¼   ENZYMATIC_REACTION ✅ 32.0 1.0 ACSN 10086337 10567412 10811803 10849428 10982827 11335727 11447289 11449354 11532940 11777939 12175651 12393695 12640133 15308668 15567848 15574420 16000375 16076871 16530705 16582911 16887996 17496910 17673906 18835194 19449109 19454690 22064427 22464172 24217602 25922287 26552706 8551221
SHC1 MAP2K4 â—¼   ENZYMATIC_REACTION ✅ 32.0 1.0 ACSN 10086337 10567412 10811803 10849428 10982827 11335727 11447289 11449354 11532940 11777939 12175651 12393695 12640133 15308668 15567848 15574420 16000375 16076871 16530705 16582911 16887996 17496910 17673906 18835194 19449109 19454690 22064427 22464172 24217602 25922287 26552706 8551221
SHC1 ANGPT1 â—¼   ENZYMATIC_REACTION ✅ 24.0 1.0 ACSN 10086337 10567412 10811803 10849428 10982827 11283723 11447289 11449354 11777939 12175651 12393695 12640133 15520864 15567848 15574420 16076871 16582911 16887996 17496910 17673906 19223473 19449109 26552706 8551221
IRS1 SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23331499 9202037 10807918 7499194
SYK SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 45.0 1.0 Omnipath 19901323 9388490 9096689 16497976 15592455 9121430 10891441 17389395 11687594 10482988 20068231 10592173 9685404 9927207 15688026 7896829 9199344 9710204 17016520 11075717
GAB2 SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 8995358 10704825
FLT4 SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 9388490 7675451 9096689 15592455 9121430 9446569 10891441 11687594 23331499 10921922 10482988 10764799 12522270 9685404 10896916 9927207 8662748 8702728 12237775 8610109 9741627 9710204 10816433 11075717
TGFBR1 SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 12767520 22710166 23331499 19010789 16474430 19920116 22943793 17934056 20519943 12809600 21900405 11133108 14557817 15548370 17673906
ERBB4 SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 16273093 16729043 24658140
TGFB1 SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 12767520 22710166 19010789 16474430 19920116 22943793 17934056 20519943 12809600 21900405 11133108 14557817 15548370 17673906
SYK TUBA4A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 9490415 8617742
SYK ITGB3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 17353363 18088087 11940607 15699036 11042121 8631894 11723131 11719224
SYK GAB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11895767 16371368 18950707
MAP3K7 CAMK2A â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 12556497 10380924 10391246 10488343 12482967
CHUK MAP3K7 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 20300203 9744859 17047224 11460167 17496917 14514672
MAP3K7 IL2RA â—¼   ENZYMATIC_REACTION ✅ 26.0 1.0 ACSN 10391247 11280761 11460167 12620219 14633987 14660645 15082531 15125833 15282297 16200688 16603398 16799562 17301840 17363905 18264787 18641653 19161412 20060931 20164171 21041997 21133840 21232017 22941947 24403530 24699077 24958845
MAP3K7 MAP2K4 â—¼   ENZYMATIC_REACTION ✅ 25.0 1.0 ACSN 10391247 11280761 11460167 11477091 12620219 14633987 14660645 15082531 15125833 16603398 16799562 17301840 17363905 18264787 18641653 19161412 20164171 21041997 21133840 21232017 22941947 23681101 24403530 24699077 24958845
PPP2CA MAP3K7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 18299321 17079228
MAP3K7 CHUK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 17145710 14960582 16893890 15836773 33895773 12547194 25241761 24911653 2547194 9742107 18949366 11274345 20200282 20194509 10094049 18855897 10187861
MAP3K7 MAP2K7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23331499 17110930 17709393 25241761 9890973
MAP3K7 KSR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 11741534 12941695
MAP3K7 MAP2K4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 41.0 1.0 Omnipath 11477091 17301840 13130464 18855897 15125833 24699077 9278437 17363905 18641653 24403530 20060931 21133840 21614932 9891069 12738796 21232017 9851932 18264787 10391247 16799562 23109003 12620219 14633987 12709432 8177321 19161412 22941947 23681101 12556533 11280761 15082531 26192618 14660645 24958845 20164171 11460167 16603398 21041997 11274345
JAK1 IL2RA â—¼   PHYSICAL_INTERACTION 26.0 1.0 ACSN 10807786 10820393 10849428 12095053 15289500 15563472 16212621 16799562 17371980 1825141 18758473 19528259 19833085 20856220 21840487 22224781 23124025 23650441 24829413 26755705 2965306 6164929 7512720 7521688 8683106 9625766
JAK1 IFNAR2 â—¼   PHYSICAL_INTERACTION 16.0 1.0 ACSN 11207245 11698286 11964292 12811837 14610620 14764699 15864272 17513775 19833085 21115385 21840487 21930765 21930769 7512720 7521688 7543512
JAK1 IFNAR2 â—¼   SHARES_COMPLEX 16.0 1.0 ACSN 11207245 11698286 11964292 12811837 14610620 14764699 15864272 17513775 19833085 21115385 21840487 21930765 21930769 7512720 7521688 7543512
JAK1 IL2RA â—¼   SHARES_COMPLEX 26.0 1.0 ACSN 10807786 10820393 10849428 12095053 15289500 15563472 16212621 16799562 17371980 1825141 18758473 19528259 19833085 20856220 21840487 22224781 23124025 23650441 24829413 26755705 2965306 6164929 7512720 7521688 8683106 9625766
JAK1 IRS2 â—¼   ENZYMATIC_REACTION ✅ 32.0 1.0 ACSN 10485906 11160275 11371360 11867689 11870632 12223527 12401408 12496409 12818165 14610620 16243976 16413922 17404308 17485448 18250477 1825141 19833085 20184663 20406969 20510870 20856220 21469115 21840487 23124025 23390297 24030977 24091328 27216177 2965306 7512720 7521688 9834059
IL3RA JAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15988755
IFNAR2 JAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 9334213 23331499 7988557 12133952 23180781 16710296 18988627
PRKCZ JAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15526032
JAK1 IRS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 11591769 9233603 7499365
JAK1 IRS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 15001544 11591769 8756628 7544789 9305869 11162588 9233603 15592455 7499365 12220227
TGFB1 TGFBR1 â—¼   PHYSICAL_INTERACTION 75.0 1.0 ACSN 10678166 11013220 11133108 11274345 11278410 11279127 11792802 12154066 12717440 12724770 12738796 12767520 12809600 14557817 15003992 15099563 15265520 15282297 15548370 15653932 15761148 15761153 16127449 16200688 16424049 16474430 16572188 17070508 17404308 17673906 17768418 17934056 17979848 18423981 18490733 18758450 18855897 18922473 19010789 19038247 19050695 19109155 19732719 19747910 19920116 20060931 20519943 20538542 20616810 20644162 21041659 21098712 21278795 21372296 21614932 21900405 22315516 22703233 22710166 22874531 22943793 22949611 23034983 23070005 23784029 24132110 24336330 24403530 26201938 26966341 2871107 7594497 8515656 9311995 9865696
TGFB1 TGFBR1 â—¼   SHARES_COMPLEX 75.0 1.0 ACSN 10678166 11013220 11133108 11274345 11278410 11279127 11792802 12154066 12717440 12724770 12738796 12767520 12809600 14557817 15003992 15099563 15265520 15282297 15548370 15653932 15761148 15761153 16127449 16200688 16424049 16474430 16572188 17070508 17404308 17673906 17768418 17934056 17979848 18423981 18490733 18758450 18855897 18922473 19010789 19038247 19050695 19109155 19732719 19747910 19920116 20060931 20519943 20538542 20616810 20644162 21041659 21098712 21278795 21372296 21614932 21900405 22315516 22703233 22710166 22874531 22943793 22949611 23034983 23070005 23784029 24132110 24336330 24403530 26201938 26966341 2871107 7594497 8515656 9311995 9865696
FOS TGFB1 â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 ACSN 15067049 15749884 16243976 16327802 16393692 16394015 16413922 16713974 17404308 17485448 19667062 20547845 21372296 21385848 22634314 23390297 23430059 9064320
TGFB1 TGFBR1 â—¼   ENZYMATIC_REACTION ✅ 75.0 1.0 ACSN 10678166 11013220 11133108 11274345 11278410 11279127 11792802 12154066 12717440 12724770 12738796 12767520 12809600 14557817 15003992 15099563 15265520 15282297 15548370 15653932 15761148 15761153 16127449 16200688 16424049 16474430 16572188 17070508 17404308 17673906 17768418 17934056 17979848 18423981 18490733 18758450 18855897 18922473 19010789 19038247 19050695 19109155 19732719 19747910 19920116 20060931 20519943 20538542 20616810 20644162 21041659 21098712 21278795 21372296 21614932 21900405 22315516 22703233 22710166 22874531 22943793 22949611 23034983 23070005 23784029 24132110 24336330 24403530 26201938 26966341 2871107 7594497 8515656 9311995 9865696
TGFB1 TGFBR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 22326956 10187774 7852346 22703233 12809600 7706250 11323414 8047140 8235612 26194464
TGFBR1 EGF â—¼   ENZYMATIC_REACTION ✅ 41.0 1.0 ACSN 11279127 11792802 12809600 14557817 15003992 15099563 15265520 15653932 16424049 16474430 16572188 17070508 17768418 17934056 17979848 18423981 18490733 19038247 19109155 19747910 20060931 20519943 20538542 20616810 20644162 21041659 21098712 21278795 21372296 21614932 22703233 22874531 23034983 23784029 24132110 24336330 26201938 26966341 2871107 7594497 8515656
TGFBR1 MAP2K4 â—¼   ENZYMATIC_REACTION ✅ 17.0 1.0 ACSN 11274345 12738796 14557817 15265520 15282297 16200688 16474430 17934056 18855897 20060931 20519943 21614932 22703233 23070005 24132110 24336330 24403530
TGFBR1 PPP2R2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 9774674
KLF8 AXIN1 â—¼   PHYSICAL_INTERACTION 28.0 1.0 ACSN 11955436 11967263 12051714 15001769 15576399 16039586 16288291 16940750 17143292 17306568 17666529 17671186 17936032 19619488 19623618 19751508 20006983 20705860 21151179 21285352 22270359 22290435 22761862 23343194 24023259 25730849 7542250 8666229
AXIN1 FZD2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11336703 17529994 18077588 17569865
KLF8 AXIN1 â—¼   SHARES_COMPLEX 28.0 1.0 ACSN 11955436 11967263 12051714 15001769 15576399 16039586 16288291 16940750 17143292 17306568 17666529 17671186 17936032 19619488 19623618 19751508 20006983 20705860 21151179 21285352 22270359 22290435 22761862 23343194 24023259 25730849 7542250 8666229
KLF8 AXIN1 â—¼   ENZYMATIC_REACTION ✅ 28.0 1.0 ACSN 11955436 11967263 12051714 15001769 15576399 16039586 16288291 16940750 17143292 17306568 17666529 17671186 17936032 19619488 19623618 19751508 20006983 20705860 21151179 21285352 22270359 22290435 22761862 23343194 24023259 25730849 7542250 8666229
CHUK AXIN1 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 11955436 11967263 12051714 12799363 23430059 7542250 8666229
DVL2 AXIN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 10329628 10829020 21245303 23892894 16713569 17529994
PPP2CA AXIN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 19131971 23331499 10644691 9920888 10026142 11742073 10995457 18042541 18559511 16680151 10421629
CSNK1D AXIN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21316585 12000790
ECSIT NDUFAF1 â—¼   PHYSICAL_INTERACTION 9.0 1.0 ACSN 10465784 15526035 16200211 16218961 17344420 20025615 20816094 25371197 26989860
ECSIT NDUFAF1 â—¼   SHARES_COMPLEX 9.0 1.0 ACSN 10465784 15526035 16200211 16218961 17344420 20025615 20816094 25371197 26989860
GLI2 CUL3 â—¼   PHYSICAL_INTERACTION 18.0 1.0 Reactome 15198976 19852954 20360384 21878643 19684112 9874371 16651542 15115751 19955409 20154143 20487519 20014402 20956384 19818708 16740475 24072710 14528312 23955340
BCAP31 CASP8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 9334338 17145710 12668660
CASP8 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 17170703 9535906 16713569
EIF2AK2 CHUK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10723127 10648614
CHUK IRS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 16510874 23343194 21285352 22020335 23296977 11274345 16039586 17439715 20920541 20530697 15337521 8545107 19619488 19623618 17565603 17143292 20006983
IFNA4 IFNAR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 21856167
PRKCZ NCF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 8626435 12734380 96198102 11145703 12056906 94375440 8089108
KSR1 BRAF â—¼   PHYSICAL_INTERACTION 47.0 1.0 ACSN 10086337 10567412 10811803 10843677 10982827 11034387 11062502 11385609 11447289 11777939 11907067 12040186 12175651 12419216 12640133 12782630 14585353 14764585 15169888 15536084 15547943 15567848 15574420 15735649 15863030 16102570 16227978 16488589 16582911 16887996 17178906 17395718 17496910 17613518 17673906 19449109 19541618 19565474 19568798 19615955 21102635 22435554 24027568 26552706 7510700 8551221 9510155
KSR1 BRAF â—¼   SHARES_COMPLEX 47.0 1.0 ACSN 10086337 10567412 10811803 10843677 10982827 11034387 11062502 11385609 11447289 11777939 11907067 12040186 12175651 12419216 12640133 12782630 14585353 14764585 15169888 15536084 15547943 15567848 15574420 15735649 15863030 16102570 16227978 16488589 16582911 16887996 17178906 17395718 17496910 17613518 17673906 19449109 19541618 19565474 19568798 19615955 21102635 22435554 24027568 26552706 7510700 8551221 9510155
FOS KSR1 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 11274345 12738796 15067049 16393692 16394015 18039929 19667062 21385848 22634314 23430059 9064320
PPP2CA KSR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18039929 16680151 10995457 18042541 18588945
KSR1 BRAF â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 19541618 8601312 19933846 12932319 17613518 18332145 15710605
MAP3K5 MAP2K4 â—¼   ENZYMATIC_REACTION ✅ 14.0 1.0 ACSN 11274345 12556535 12655147 12738796 15592525 17462996 18641653 18855897 19392652 21133840 21232017 21614932 23850759 24378531
MAP3K5 MAP2K7 â—¼   ENZYMATIC_REACTION ✅ 14.0 1.0 ACSN 11274345 12556535 12655147 12738796 15592525 17462996 18641653 18855897 19392652 21133840 21232017 21614932 23850759 24378531
YWHAQ MAP3K5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 17145710 15023544 17389591 19880523
MAP3K5 MAP2K7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 12556535 19392652 18855897 17462996 19920149 18641653 23331499 23850759 21071413 12655147 21614932 21133840 12738796 21232017 24378531 15592525 11959862 17110930 26192618 11274345
MAP3K5 MAP2K4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 35.0 1.0 Omnipath 12556535 18408005 18855897 19392652 9162092 17462996 8974401 18641653 23331499 23850759 12655147 21614932 15911620 12738796 21133840 15998799 21232017 17541429 16000309 24378531 15592525 11053428 26192618 12878192 11274345
PRKCZ YWHAB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 16189514 10620507 21900206
YWHAE YWHAB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 20936779 17085597 12507503 24255178 17979178
BRAF YWHAB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 17145710 12620389 17353931 24255178 15324660 10931830
YWHAB YWHAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17085597 12657644 12426317 15071501
YWHAB YWHAE â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 20936779 17085597 12507503 24255178 17979178
DVL2 LRRK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23331499 20006983 19625296
DVL2 FZD2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17234765 18077588 14636582 22411803
CSNK1D DVL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 21316585 22609948 29426949 31579410
DVL2 ARRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12958364
FLT4 MAP2K4 â—¼   ENZYMATIC_REACTION ✅ 32.0 1.0 ACSN 10086337 10567412 10811803 10849428 10982827 11335727 11447289 11449354 11532940 11777939 12175651 12393695 12640133 15308668 15567848 15574420 16000375 16076871 16530705 16582911 16887996 17496910 17673906 18835194 19449109 19454690 22064427 22464172 24217602 25922287 26552706 8551221
FLT4 MAP2K4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 17496910 18000759 15574420 19151919 11777939 18855897 21614932 12738796 11274345 12040186 19568798 14585353
CDC42 PRKCZ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23109003 17353362 10733591 10873802
CD4 CD3D â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
CSNK1D GLI2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 21233202 7641885 16611981 21536646 19797085 18455992 16371461
AR EGF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 18511414 8580999 7522959 15590903 14662770 18692155 17374439 18212060 20610535
RPS6KB1 IRS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 47.0 1.0 Omnipath 21283818 17081983 16953237 24931005 11287630 15249583 27898058 16914728 25379019 23565163 15364919 15533996 19121779 9312143 17709744 20074531 22523661 23958494 16129690 23006971 23898460 26474286 28342808 17507185 25813876 26926384 15306821 20932932 34013180 15199052 18498745 18952604 18220336 12006582 19369195 29496905 27889207 26666849
PRKCZ IRS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 11063744 16129678 16611834 14583092 17360977 15212693 15516986 15069075
PTPN1 IRS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 23331499 21071413 11579209 10660596 10592173 18988627 10751417
SIK2 IRS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 12006586 22869320 22970990 15134808 24841198 22207502 12624099
IGF1 IRS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 26474286 28545881 26956053 25886138 15952059 18762365 22362362 19762915 11160134 22941977
AR IGF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 24914937 8580999 17363459 22739988
FGF20 FGFR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16597617 25772309
GAPDH AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16713569 8872471
BRAF YWHAG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 17145710 17353931 15324660
YWHAE YWHAG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 21988832 20936779 17085597 12507503 17979178
YWHAG YWHAE â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 21988832 20936779 17085597 12507503 17979178
YWHAG YWHAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17085597 21827211 12426317 15324660 15071501 12657644
YWHAH YWHAE â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 20936779 12507503 7615088 26496610 17979178
YWHAZ YWHAE â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 21988832 20936779 20618440 26496610 16376338 17979178 19766566
YWHAE YWHAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 21988832 20936779 20618440 17085597 21827211 12426317 15071501 12657644 17979178
YWHAE YWHAZ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 21988832 20936779 20618440 26496610 16376338 17979178 19766566
YWHAE YWHAH â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 20936779 12507503 7615088 26496610 17979178
AR GRB10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 24931201 20610535
PPP2R1B PPP2CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18715871 17540176 19114990
PPP2R1A PPP2CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 35.0 1.0 Omnipath 21159657 23443559 19818709 19293187 24841198 28330616 18715871 19915589 18782753 33633399 17274953 26496610 17540176 15761952 17374643 17529992 22379092 17055435 8617797 12370081 17632056 16039140 16769727 19156129
PPP2CA ARRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 18039929 16680151 10995457 18042541 18588945
PPP2CA RPS6KB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 16109716 2826472 16899564 11438723 11124802 10200280
YWHAH BRAF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 8085158 8085159 10931830 7744815 8668348
BRAF YWHAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16713569 8668348 17353931 15324660
BRAF YWHAZ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 17145710 17353931 8668348 15324660 15161933
CSNK1D YWHAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9360956 16045749 17081983 98030561
YWHAH YWHAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21827211 12657644 12426317 15071501
YWHAZ YWHAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21827211 12657644 12426317 15071501