Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list
Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins
Filter Graph:

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Layout:
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
TRAV19 PTPN22 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 Reactome 22426112 16461343
TRAV19 TRBC1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
TRAV19 TRBV7-9 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
TRAV19 HLA-DQA2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
TRAV19 CSK â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15489916 15489910
TRAV19 PRKCQ â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 16978534 12473184
TRAV19 HLA-DQA1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
TRAV19 CD247 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
TRAV19 CD3E â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
TRAV19 CD4 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
TRAV19 TRBV12-3 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
TRAV19 HLA-DRA â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
TRAV19 LCK â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
TRAV19 CD3D â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
TRAV19 ZAP70 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
TRAV19 HLA-DPA1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
TRAV19 TRAV8-4 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
TRAV19 ZAP70 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8520027 9850860
TRAV19 TRAC â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
TRAV19 CD3G â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
TRAV19 TRAV29DV5 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
TRBV12-3 ZAP70 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8520027 9850860
CD4 TRBV12-3 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
TRBV12-3 CD3D â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
TRBV12-3 HLA-DQA2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
TRBV12-3 TRBC1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
TRBV12-3 CSK â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15489916 15489910
TRBV12-3 TRAC â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
TRBV12-3 HLA-DRA â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
TRBV12-3 TRAV29DV5 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
TRBV12-3 TRBV7-9 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
TRBV12-3 LCK â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
TRBV12-3 CD3E â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
TRBV12-3 HLA-DPA1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
TRBV12-3 ZAP70 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
TRBV12-3 TRAV8-4 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
TRBV12-3 CD247 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
TRBV12-3 CD3G â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
TRBV12-3 HLA-DQA1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
TRBV12-3 PRKCQ â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 16978534 12473184
TRBV12-3 PTPN22 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 Reactome 22426112 16461343
TRAV8-4 TRAV29DV5 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
TRAV8-4 HLA-DRA â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
TRAV8-4 HLA-DQA1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
TRAV8-4 TRBV7-9 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
TRAV8-4 HLA-DQA2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
TRAV8-4 CSK â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15489916 15489910
TRAV8-4 TRAC â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
TRAV8-4 CD247 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
CD4 TRAV8-4 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
TRAV8-4 PRKCQ â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 16978534 12473184
TRAV8-4 ZAP70 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
TRAV8-4 LCK â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
TRAV8-4 CD3E â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
TRAV8-4 CD3G â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
TRAV8-4 HLA-DPA1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
TRAV8-4 TRBC1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
TRAV8-4 PTPN22 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 Reactome 22426112 16461343
TRAV8-4 CD3D â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
TRAV8-4 ZAP70 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8520027 9850860
TRBV7-9 ZAP70 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8520027 9850860
TRAC TRBV7-9 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
CD4 TRBV7-9 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
HLA-DRA TRBV7-9 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
CD3D TRBV7-9 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
HLA-DQA2 TRBV7-9 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
TRBC1 TRBV7-9 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
HLA-DQA1 TRBV7-9 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
TRBV7-9 PRKCQ â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 16978534 12473184
TRBV7-9 CD247 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
TRBV7-9 TRAV29DV5 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
TRBV7-9 CSK â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15489916 15489910
TRBV7-9 LCK â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
TRBV7-9 CD3G â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
TRBV7-9 CD3E â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
TRBV7-9 HLA-DPA1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
TRBV7-9 ZAP70 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
TRBV7-9 PTPN22 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 Reactome 22426112 16461343
PTPN6 CSK â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18173375 18759926
FYN CSK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7524477 6730342
CSK PTPN11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18173375 18759926
CD247 CSK â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15489916 15489910
CD3E CSK â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15489916 15489910
HLA-DPA1 CSK â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15489916 15489910
HLA-DQA1 CSK â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15489916 15489910
HLA-DQA2 CSK â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15489916 15489910
TRAV29DV5 CSK â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15489916 15489910
CD3G CSK â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15489916 15489910
HLA-DRA CSK â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15489916 15489910
TRBC1 CSK â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15489916 15489910
LCK CSK â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15489916 15489910
CD3D CSK â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15489916 15489910
TRAC CSK â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15489916 15489910
CD4 CSK â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15489916 15489910
CSK PTPRC â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 6672875 7507203
CSK PTPN11 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 Reactome 15574420 14665621
FYB1 FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 9207119 5221556
CD1B B2M â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12118248 5215540
PIK3R1 B2M â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15536084 11907067
GNAI1 GNG2 â—¼   PROXIMITY 2.0 0.8 intact 8189321 21552208
TRAC ZAP70 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8520027 9850860
TRAC TRBC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5215899 12429093
CD4 TRAC â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
TRAC TRBC1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
TRAC TRAV29DV5 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
TRAC PRKCQ â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 16978534 12473184
TRAC HLA-DRA â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
TRAC CD3G â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
TRAC HLA-DPA1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
TRAC LCK â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
TRAC ZAP70 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
TRAC HLA-DQA2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
TRAC CD3E â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
TRAC CD247 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
TRAC HLA-DQA1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
TRAC CD3D â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
TRAC PTPN22 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 Reactome 22426112 16461343
TRAV29DV5 LCK â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
TRAV29DV5 CD247 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
HLA-DQA1 TRAV29DV5 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
HLA-DQA2 TRAV29DV5 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
TRAV29DV5 CD3E â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
CD3D TRAV29DV5 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
TRAV29DV5 ZAP70 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8520027 9850860
TRAV29DV5 CD3G â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
TRAV29DV5 HLA-DPA1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
TRBC1 TRAV29DV5 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
TRAV29DV5 PRKCQ â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 16978534 12473184
TRAV29DV5 ZAP70 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
CD4 TRAV29DV5 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
TRAV29DV5 PTPN22 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 Reactome 22426112 16461343
HLA-DRA TRAV29DV5 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
TRBC1 ZAP70 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8520027 9850860
CD4 TRBC1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
TRBC1 CD3D â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
TRBC1 HLA-DQA1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
TRBC1 PRKCQ â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 16978534 12473184
TRBC1 LCK â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
TRBC1 CD3E â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
TRBC1 HLA-DQA2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
TRBC1 CD3G â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
TRBC1 HLA-DPA1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
TRBC1 ZAP70 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
TRBC1 HLA-DRA â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
TRBC1 CD247 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
TRBC1 PTPN22 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 Reactome 22426112 16461343
CD3D AMFR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16407162 0506618103
FYN CBL â—¼   PHOSPHORYLATION ✅ 0.8 0.8 mint 5217342 15556646
CBL FYN â—¼   PHOSPHORYLATION ✅ 0.8 0.8 mint 5217342 15556646
SHC1 CD247 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7544002 6730386
VAV1 CD247 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8986718 16546099
CD247 CD3G â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HLA-DQA1 CD247 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
HLA-DQA2 CD247 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
CD3G CD247 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
HLA-DRA CD247 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
CD3E CD247 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
HLA-DPA1 CD247 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
CD3D CD247 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
CD247 PRKCQ â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 16978534 12473184
CD247 PTPN22 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 Reactome 22426112 16461343
PTPRC CD247 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 7526385
LCK CD28 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8946678 9973466
FYN CD28 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8946678 9973466
HLA-DRA CD3D â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
HLA-DQA2 CD3D â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
CD4 CD3D â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
HLA-DQA1 CD3D â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
CD3D ZAP70 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
CD3D CD3G â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
CD3D LCK â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
CD3D PRKCQ â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 16978534 12473184
CD3D CD3E â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
CD3D HLA-DPA1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
ETS1 CD3D â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12324448
CD3D PTPN22 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 Reactome 22426112 16461343
CD3E SHC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6731413 11855827
HLA-DQA2 CD3E â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
LCK CD3E â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
CD4 CD3E â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
HLA-DQA1 CD3E â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
HLA-DRA CD3E â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
CD3E HLA-DPA1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
CD3E CD3G â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
CD3E PRKCQ â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 16978534 12473184
CD3E ZAP70 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
CD3E PTPN22 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 Reactome 22426112 16461343
CD3G VAV1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8986718 16546099
CD4 CD3G â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
LCK CD3G â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
HLA-DQA1 CD3G â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
HLA-DRA CD3G â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
HLA-DQA2 CD3G â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
CD3G ZAP70 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
CD3G PRKCQ â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 16978534 12473184
CD3G HLA-DPA1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
CD3G PTPN22 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 Reactome 22426112 16461343
CD4 HLA-DRA â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
CD4 HLA-DQA1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
CD4 HLA-DQA2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
CD4 HLA-DRA â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
CD4 LCK â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
CD4 HLA-DPA1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
CREB1 CD4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9765424
CD4 PTPN22 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 Reactome 22426112 16461343
HLA-DPA1 CD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12899833 16189514
PIK3R1 CD80 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12670391 8621607
LCK CD80 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8946678 9973466
FYN CD80 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8946678 9973466
CD80 PTPN11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9712716 10694513
CD80 GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9694876 7737275
FYN CD86 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8946678 9973466
LCK CD86 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8946678 9973466
PIK3R1 CD86 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12670391 8621607
CD86 PTPN11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9712716 10694513
CD86 GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9694876 7737275
ETS1 CD8A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8413295
EOMES CD8A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17566017 20060330
CREB1 IL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21084670
DBNL UBQLN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ERLIN2 PLCG1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15050920 10579907
ETS1 LCK â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7970721
ETS1 IL2RB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8413220
FOS ETS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16189514 8557686
SHC1 FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7516469 5220322
LCP2 FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6546918 15929943
PDIA2 FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
LCK FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8946678 9973466
FYN GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9694876 7737275
FYN MAP4K1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
FYN LCK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17570479 22043010
GNB1 GNAI2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7102203 16782902
VCP GNAO1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
GRAP2 PLCG1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11390650 11048639
GRAP2 LCP2 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
PDIA2 GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
LCK GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9694876 7737275
PTPN6 GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 10660620 6671678
GRB2 IL2RG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
VAV1 GRB2 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
GRB2 PTPN11 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 Reactome 17993263 15031289
IL2RB GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16189514 10602027
GRB2 ITK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10636929
HLA-DPA1 ZAP70 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8520027 9850860
HLA-DQA2 HLA-DPA1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
HLA-DQA1 HLA-DPA1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
LCK HLA-DPA1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
HLA-DRA HLA-DPA1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
HLA-DPA1 PRKCQ â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 16978534 12473184
HLA-DPA1 ZAP70 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
HLA-DPA1 PTPN22 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 Reactome 22426112 16461343
HLA-DQA1 ZAP70 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8520027 9850860
HLA-DRA HLA-DQA1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
HLA-DQA2 HLA-DQA1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
HLA-DQA1 PRKCQ â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 16978534 12473184
HLA-DQA1 LCK â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
HLA-DQA1 ZAP70 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
HLA-DQA1 PTPN22 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 Reactome 22426112 16461343
HLA-DQA2 ZAP70 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8520027 9850860
HLA-DRA HLA-DQA2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
HLA-DQA2 PRKCQ â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 16978534 12473184
HLA-DQA2 LCK â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
HLA-DQA2 ZAP70 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
HLA-DQA2 PTPN22 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 Reactome 22426112 16461343
HLA-DRA ZAP70 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8520027 9850860
HLA-DRA LCK â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
HLA-DRA ZAP70 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
HLA-DRA PRKCQ â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 16978534 12473184
HLA-DRA PTPN22 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 Reactome 22426112 16461343
IFNB1 PTPN11 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 Reactome 10022928 18508557
IFNB1 PTPN6 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 Reactome 8943354 18508557
IKZF1 IFNG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19923223 19828627
IL2RB IL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15178252 16477002
IL2RA IL2RB â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15178252 16477002
IL2RA IL2RG â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15178252 16477002
JUN IL2RA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14660657 7889400
IL2RG SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16189514 8643566
IL2RG PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10421845
JUN UBQLN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
LAT SHC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10811803 8663278
LAT PTPRJ â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 intact 11259588 6673177
ZAP70 LCK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5211965 10556826
PIK3R1 LCK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5220762 8246987
LCK PTPN11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18173375 18759926
LCK PTPN6 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 8114715 7028063
LCK PTPRC â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 6672875 7507203
PLCG1 LCP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6546918 15929943
SHC1 LCP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6548125 9716598
PLCG1 MAP4K1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
PIK3R1 MAP4K1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
MAP4K1 PLCG1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
PTPN11 PAG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10790433 14967142
PDIA2 PIK3R1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
PLCG1 PDIA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
PLCG1 PIK3R1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6805619 9020117
PTPRJ PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18348712
ZAP70 PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17038529
VAV1 PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16713569 11331248
PIK3R1 VAV1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16713569 11331248
PLCG1 PTPN11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6805619 9020117
PTPN6 SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8541543
ZAP70 SHC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15688026 5217506
GRB2 MAP4K1 â—¼   PHYSICAL_INTERACTION 806.0 0.8 STRING 36370105
LCK CD3E â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 11855827 14523017
CD28 GRAP2 â—¼   PHYSICAL_INTERACTION 817.0 0.81 STRING 36370105
GRB2 CSK â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21706016 31980649
FYN FYB1 â—¼   PHYSICAL_INTERACTION ✅ 0.82 0.82 mint 9207119 5221556
CD1B CALX â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
DERL1 CALX â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28137758 34079125
CD3D TERA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17872946 15331598
CD3D AMFR1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 16407162 17872946
SHC1 PIK3R1 â—¼   PHYSICAL_INTERACTION ✅ 0.82 0.82 mint 16219545 5217992
SHC1 SHC2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SHC3 GRB2 â—¼   RELOCALIZATION ✅ + 0.82 0.82 Signor 16829981
CSK JUN â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 19818398 16740711
CD1D CALX â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 12239218 16189514
GRB2 ZAP70 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 7629168 23267066
SHC1 IL2RG â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 16189514 8643566
LCP2 SHC1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 9716598 16189514
AMFR ERLIN2 â—¼   PHYSICAL_INTERACTION 833.0 0.83 STRING 36370105
CD247 CD3D â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
CD3D CD3G â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
GNAI1 RGS1 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
CBL LCP2 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
LCK PTPN6 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
CSK LCK â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 15144186 12485116 31980649
ZAP70 FYN â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 7760813 16189514 16713569
CD8A LCK â—¼   PHYSICAL_INTERACTION 848.0 0.84 STRING 36370105
LAT ZAP70 â—¼   PHYSICAL_INTERACTION 849.0 0.84 STRING 36370105
CALX TERA â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 31536960 23383273 17948026 26344197
AMFR1 DERL1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 16186510 17872946 18216283 32614325 21832065
CD86 CD28 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 7513726 21931534 11021528 27708164
SYVN1 DERL1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 16186510 29743537 16289116 24807418 23867461 19864457 26471130
IL2RB GRB2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 10602027 16189514
PTPRC LCK â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 7507203 6672875
LCK LCP2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 10556826 16354835 8702662 21725281
PTPRC LCK â—¼   PHOSPHORYLATION ✅ 0.85 0.85 mint 7507203 6672875
PTPRC LCK â—¼   DEPHOSPHORYLATION ✅ 0.85 0.85 mint 10369126 8310409
LCK PTPRC â—¼   DEPHOSPHORYLATION ✅ 0.85 0.85 mint 7507203 6672875
PLCG1 SHC1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 8662733 10652211 8155326
CD8A CD8B â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
CBL CSK â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 19380743 11149930
CSK PTPRC â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 19167335 7507203
CD3D CALX â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 25241761 8278814 8621641 33961781
GRAP2 CBL â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 25814554 12496419
CREB1 JUN â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 25609649 2138276
PIK3R1 GRB2 â—¼   PHYSICAL_INTERACTION ✅ 0.86 0.86 mint 5220480 7642581
ITK GRB2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 8985255 10636929
IL2RA IL2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 17032757 1993646 16477002
ZAP70 LCP2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 8702662 10660534 12190313 24584089 9047237
GNAI1 GNAI2 â—¼   PHYSICAL_INTERACTION 861.0 0.86 STRING 36370105
SHC1 ZAP70 â—¼   PHYSICAL_INTERACTION 869.0 0.86 STRING 36370105
VAV1 ZAP70 â—¼   PHYSICAL_INTERACTION 869.0 0.86 STRING 36370105
AMFR DERL1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
ITK FYN â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 10636929 8810341 16713569
GNAI1 GNAI3 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
LAT ITK â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 12186560 10506192
ZAP70 LAT â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 11368773 12186560 23514740 16906159
LCP2 ZAP70 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
ZAP70 PLCG1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 7629168 8906806 16467851
CBL VAV1 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
B2M CD1C â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
GNAI2 GNG2 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
LCP2 VAV1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
CD28 GRB2 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
CD247 LCK â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
PIK3R1 SHC1 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
LCP2 CBL â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 9716598 10204582 19635790 10477741
JUN ETS1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 8557686 20195357
CD3E ZAP70 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
LAT PLCG1 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
LCK PTPRC â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
LCP2 PLCG1 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
CBL PLCG1 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
ITK LCP2 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
LCK ZAP70 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
GNAI2 GNAI3 â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
CBL LCK â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
CD3D CD3E â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
CBL SHC1 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
GRB2 LCP2 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
SHC1 CSK â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10037694 19380743 12048194
CANX VCP â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
ZAP70 DBNL â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 14557276 16189514
GRAP2 LAT â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10224278 10021361 16189514
SHC1 IL2RB â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10602027 16189514 8294403
ITK PLCG1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10586033 12163161
GRB2 VAV1 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
DERL1 SYVN1 â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
FYB1 LCP2 â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 9207119 5221556
LCP2 FYB1 â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 9207119 5221556
CD8A B2M â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15136729 15534202 16551255
CANX B2M â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 14681859 2450918 10064069
CD8B B2M â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15136729 15534202 16551255
DERL1 TERA â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 16186510 16289116 29599191 16901789 28137758 18199748 17872946 21909096 34079125 34739333 29540532 15215856 16186509 22119785 27714797
AMFR1 TERA â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 19828134 21914798 16987818 23383273 28301499 17311810 27387505 22119785 26424800 20126661 18835813 16186510 29599191 16275660 17681147 21343306 22328510 23333620 21636303 17872946 24100225 15331598
HLA-DQA1 CANX â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 9312039 1956401 16618111
HLA-DQA2 CANX â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 9312039 1956401 16618111
HLA-DPA1 CANX â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 9312039 1956401 16618111
HLA-DRA CANX â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 9312039 1956401 16618111
ZAP70 CBL â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 10074432 29053960 10078535 11353765 11133830 9407100 8798643 10779765 9988730 22266821 16503409
PTPN6 CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11157475 12176909
PLCG1 CD247 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 7517665 8657103 15161916
GRAP2 CD28 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 24475931 27927989 10820259
PIK3R1 CD28 â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 6730476 7807015
CD28 CD80 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 7964482 7545666 21982860 1847722 2164219
CD3G PLCG1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 7517665 8657103 15161916
ETS1 CD4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19917777 8356078 9780181
VAV1 CD80 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18295596 15886116 10849438
VAV1 CD86 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18295596 15886116 10849438
VCP DERL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17145710 15215856
EOMES PRF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20096607 17566017 23409078
JUN ETS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 1945412 8247540
FYN GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 7499280 9344857
FYN LAT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16938345
LAT GRB2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 10811803 23460737 7544353 9489702 12359715 12186560 16938345 16713569 16906159 8063801 11368773 16189514
SHC3 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16729043 12242309 16829981
HLA-DQA1 HLA-DPA1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 9312039 1956401 16618111
HLA-DQA2 HLA-DPA1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 9312039 1956401 16618111
HLA-DRA HLA-DPA1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 9312039 1956401 16618111
HLA-DRA HLA-DQA1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 9312039 1956401 16618111
HLA-DQA2 HLA-DQA1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 9312039 1956401 16618111
HLA-DRA HLA-DQA2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 9312039 1956401 16618111
LCK LAT â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 12186560 14523017 16938345 12359715
LCK PLCG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 7682059 17570479 1500851
VAV1 SHC1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 9209406 8677749 7539782
VCP DERL1 â—¼   PHYSICAL_INTERACTION ✅ + 0.9 0.9 Signor 15215856
GRB2 PIK3R1 â—¼   PHYSICAL_INTERACTION 908.0 0.9 STRING 36370105
PIK3R1 PTPN11 â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
GRB2 CBL â—¼   RELOCALIZATION ✅ + 0.91 0.91 Signor 11823423
CD28 PIK3R1 â—¼   PHYSICAL_INTERACTION 919.0 0.91 STRING 36370105
ZAP70 CD247 â—¼   PHYSICAL_INTERACTION ✅ 0.92 0.92 mint 7528772 6730352
CD247 CD3E â—¼   PHYSICAL_INTERACTION 923.0 0.92 STRING 36370105
GRAP2 LCP2 â—¼   PHYSICAL_INTERACTION 923.0 0.92 STRING 36370105
CBL FYN â—¼   PHYSICAL_INTERACTION 925.0 0.92 STRING 36370105
GRAP2 MAP4K1 â—¼   PHYSICAL_INTERACTION 929.0 0.92 STRING 36370105
CD247 SHC1 â—¼   PHYSICAL_INTERACTION 931.0 0.93 STRING 36370105
AMFR VCP â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
CD3E CD3G â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
B2M CD8A â—¼   PHYSICAL_INTERACTION 936.0 0.93 STRING 36370105
IL2RB IL2RG â—¼   PHYSICAL_INTERACTION 939.0 0.93 STRING 36370105
PIK3R1 CBL â—¼   PHYSICAL_INTERACTION ✅ 0.94 0.94 mint 5217342 15556646
CD3G CD3E â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 9582308 2138083 20890284
GRB2 PTPN11 â—¼   PHYSICAL_INTERACTION 949.0 0.94 STRING 36370105
IL2RG IL2 â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 16477002 10662798 8006584 8049354 22446627 11418623
SHC1 CBL â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 9234717 9541596 15677445 8621719 16713569 8950973 10025673 10570290 8662998 19380743 9461587 9434624
PLCG1 GRB2 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 21706016 7629168 10940929 16038803 9020117 16713569 9281317 7516467
B2M CD1A â—¼   PHYSICAL_INTERACTION 968.0 0.96 STRING 36370105
TERA SYVN1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 16186510 16289116 20414249 26424800 17872946 24100225 26471130 16822850
FYN CBL â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 9677430 8621719 12244174 7782294 10629042 119942 7642581 15556646 12231245 9311917 9535867 8626543 10799548 16713569 16503409 10092522 8900205 8995358 25814554 9890970 15190072 15208330 12941616 10829062 11239464 8662998 17094785
PLCG1 CBL â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 9234717 12941616 25241761 16467851 12061819 9712732 16713569 16503409 17372230 12803489
LCP2 GRB2 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 10224278 8695800 32296183 19380743 9565634 11314042 7706237 20936779 12176364 10204582 8995445 25416956 9716598 15929943 17235283
LCP2 ITK â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 10556826 21725281 15388330 17420479 10636929 12190313
CD4 LCK â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
B2M CD1D â—¼   PHYSICAL_INTERACTION 979.0 0.97 STRING 36370105
DERL1 VCP â—¼   PHYSICAL_INTERACTION 979.0 0.97 STRING 36370105
LCP2 GRAP2 â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 17235283 5219525
CBL ZAP70 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
GNAI1 GNG2 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
B2M CD1B â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
FOS JUN â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
GNAI2 GNB1 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
SHC1 GRB2 â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 12213123 8491186 8950973 9927207 9733714 8112292 10356320 11370743 32062451 8294403 16371368 22057045 9045692 9032244 8995379 7514169 9175774 9541596 8663178 7629070 9019162 7597091 7798267 9544989 9488479 8940013 10570290 15812354 11792427 8621719 24430869 7650032 11453982 16713569 7516467 10477741 8662733 11302736 26551075 9254595 7559490 12441060 8662998 8235613 12485888 28690151 16520382 8939605 11505033 9129019 11707405 15888547 8647288 7524086 25416956 24189400 11827484 12149229 8195171 21725358 9020193 10049786 9797459 9886492 33961781 9126968 8626525 7537740 12577067 11964172 12898421 8810340 22974441 19380743 9434624 10080542 9083103 21706016 15688026 7535773 31980649 8561895 7744881
GNAI3 GNB1 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
SYVN1 VCP â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
CBL PIK3R1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CBL GRB2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
GNAI1 GNB1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
GNB1 GNG2 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
TRAV19 HLA-DPA1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
TRAV19 CD1D â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 18037897 26300885 15864273 14764708 20080535 15723809 7542404 21167756 22006319 25703557
TRAV19 HLA-DQA1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
TRAV19 PTPRJ â—¼   DEPHOSPHORYLATION ✅ 5.0 1.0 Reactome 20346773 23580664 11827988 21543337 2530588
TRAV19 PTPN6 â—¼   DEPHOSPHORYLATION ✅ 4.0 1.0 Reactome 12947224 15358536 18173375 18759926
TRAV19 HLA-DQA2 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
TRAV19 B2M â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 18037897 26300885 15864273 14764708 20080535 15723809 7542404 21167756 22006319 25703557
TRAV19 CD4 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
TRAV19 CD1B â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 18037897 26300885 15864273 14764708 20080535 15723809 7542404 21167756 22006319 25703557
TRAV19 LCK â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
TRAV19 CD1A â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 18037897 26300885 15864273 14764708 20080535 15723809 7542404 21167756 22006319 25703557
TRAV19 HLA-DRA â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
TRAV19 PTPRC â—¼   DEPHOSPHORYLATION ✅ 5.0 1.0 Reactome 20346773 23580664 11827988 21543337 2530588
TRAV19 PTPN11 â—¼   DEPHOSPHORYLATION ✅ 4.0 1.0 Reactome 12947224 15358536 18173375 18759926
TRAV19 CD1C â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 18037897 26300885 15864273 14764708 20080535 15723809 7542404 21167756 22006319 25703557
CD4 TRBV12-3 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
TRBV12-3 B2M â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 18037897 26300885 15864273 14764708 20080535 15723809 7542404 21167756 22006319 25703557
TRBV12-3 HLA-DQA2 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
TRBV12-3 HLA-DQA1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
TRBV12-3 LCK â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
TRBV12-3 CD1D â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 18037897 26300885 15864273 14764708 20080535 15723809 7542404 21167756 22006319 25703557
TRBV12-3 HLA-DRA â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
TRBV12-3 HLA-DPA1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
TRBV12-3 CD1C â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 18037897 26300885 15864273 14764708 20080535 15723809 7542404 21167756 22006319 25703557
TRBV12-3 CD1B â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 18037897 26300885 15864273 14764708 20080535 15723809 7542404 21167756 22006319 25703557
TRBV12-3 CD1A â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 18037897 26300885 15864273 14764708 20080535 15723809 7542404 21167756 22006319 25703557
TRBV12-3 PTPN11 â—¼   DEPHOSPHORYLATION ✅ 4.0 1.0 Reactome 12947224 15358536 18173375 18759926
TRBV12-3 PTPRJ â—¼   DEPHOSPHORYLATION ✅ 5.0 1.0 Reactome 20346773 23580664 11827988 21543337 2530588
TRBV12-3 PTPN6 â—¼   DEPHOSPHORYLATION ✅ 4.0 1.0 Reactome 12947224 15358536 18173375 18759926
TRBV12-3 PTPRC â—¼   DEPHOSPHORYLATION ✅ 5.0 1.0 Reactome 20346773 23580664 11827988 21543337 2530588
TRAV8-4 PTPRJ â—¼   DEPHOSPHORYLATION ✅ 5.0 1.0 Reactome 20346773 23580664 11827988 21543337 2530588
TRAV8-4 PTPN11 â—¼   DEPHOSPHORYLATION ✅ 4.0 1.0 Reactome 12947224 15358536 18173375 18759926
TRAV8-4 HLA-DQA2 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
TRAV8-4 CD1D â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 18037897 26300885 15864273 14764708 20080535 15723809 7542404 21167756 22006319 25703557
TRAV8-4 CD1B â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 18037897 26300885 15864273 14764708 20080535 15723809 7542404 21167756 22006319 25703557
TRAV8-4 HLA-DQA1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
TRAV8-4 B2M â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 18037897 26300885 15864273 14764708 20080535 15723809 7542404 21167756 22006319 25703557
TRAV8-4 CD1C â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 18037897 26300885 15864273 14764708 20080535 15723809 7542404 21167756 22006319 25703557
TRAV8-4 PTPN6 â—¼   DEPHOSPHORYLATION ✅ 4.0 1.0 Reactome 12947224 15358536 18173375 18759926
CD4 TRAV8-4 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
TRAV8-4 HLA-DPA1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
TRAV8-4 HLA-DRA â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
TRAV8-4 LCK â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
TRAV8-4 PTPRC â—¼   DEPHOSPHORYLATION ✅ 5.0 1.0 Reactome 20346773 23580664 11827988 21543337 2530588
TRAV8-4 CD1A â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 18037897 26300885 15864273 14764708 20080535 15723809 7542404 21167756 22006319 25703557
HLA-DQA2 TRBV7-9 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
CD4 TRBV7-9 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
HLA-DRA TRBV7-9 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
HLA-DQA1 TRBV7-9 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
TRBV7-9 B2M â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 18037897 26300885 15864273 14764708 20080535 15723809 7542404 21167756 22006319 25703557
TRBV7-9 HLA-DPA1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
TRBV7-9 CD1D â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 18037897 26300885 15864273 14764708 20080535 15723809 7542404 21167756 22006319 25703557
TRBV7-9 LCK â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
TRBV7-9 CD1C â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 18037897 26300885 15864273 14764708 20080535 15723809 7542404 21167756 22006319 25703557
TRBV7-9 CD1A â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 18037897 26300885 15864273 14764708 20080535 15723809 7542404 21167756 22006319 25703557
TRBV7-9 CD1B â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 18037897 26300885 15864273 14764708 20080535 15723809 7542404 21167756 22006319 25703557
TRBV7-9 PTPRJ â—¼   DEPHOSPHORYLATION ✅ 5.0 1.0 Reactome 20346773 23580664 11827988 21543337 2530588
TRBV7-9 PTPRC â—¼   DEPHOSPHORYLATION ✅ 5.0 1.0 Reactome 20346773 23580664 11827988 21543337 2530588
TRBV7-9 PTPN11 â—¼   DEPHOSPHORYLATION ✅ 4.0 1.0 Reactome 12947224 15358536 18173375 18759926
TRBV7-9 PTPN6 â—¼   DEPHOSPHORYLATION ✅ 4.0 1.0 Reactome 12947224 15358536 18173375 18759926
CSK PAG1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 ACSN 10790433 11181701 12218089 12485116 15713798 19290918 8011291 8986721
CSK FYN â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 10790433 11181701 12485116 15713798 19290918 8011291 8986721
CSK LCK â—¼   DOWN_REGULATES ✅ - 7.0 1.0 ACSN 10790433 11181701 12485116 15713798 19290918 8011291 8986721
PAG1 CSK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23331499 23109003 12614359 31125786 10790433
CSK FYN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 1985196 8262983 11489946 16537894 9647655 25720756 18691976 10366594 19369195 1533589 1699196 7524477 16713569 15713745 14967142
CSK SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 12767520 12048194 18829532 9819392 19380743 10037694 17673906
CSK LCK â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 56.0 1.0 Omnipath 20346773 19901323 10692391 11489946 22566970 24463463 2141684 16497976 15592455 20813252 10799545 14967142 27547268 24764511 28522807 16537894 12485116 8193535 24227778 17897955 8183556 22426112 89123626 15489916 14610046 23109003 18691976 28448599 17947241 1639064 12414720 15144186 27460989 24816556 22507872 8631775 15743820 25979654 8945479 11181701 27045023 25595912 15259016
CSK PTPRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 7507203 19167335
FYN FYB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 41.0 1.0 Omnipath 10229084 10570256 7504057 20661443 25814554 9207119 10497204 24769494 26246585 16713569 23979596 33431658 10409671 17474147 30305305 9748251
CD3D B2M â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 18037897 26300885 15864273 14764708 20080535 15723809 7542404 21167756 22006319 25703557
CD3E B2M â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 18037897 26300885 15864273 14764708 20080535 15723809 7542404 21167756 22006319 25703557
TRAV29DV5 B2M â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 18037897 26300885 15864273 14764708 20080535 15723809 7542404 21167756 22006319 25703557
CD3G B2M â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 18037897 26300885 15864273 14764708 20080535 15723809 7542404 21167756 22006319 25703557
TRBC1 B2M â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 18037897 26300885 15864273 14764708 20080535 15723809 7542404 21167756 22006319 25703557
CD247 B2M â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 18037897 26300885 15864273 14764708 20080535 15723809 7542404 21167756 22006319 25703557
TRAC B2M â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 18037897 26300885 15864273 14764708 20080535 15723809 7542404 21167756 22006319 25703557
B2M CD247 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 10358761 10559964 11154916 11509172 11717192 14508489 16181333 22076556 22790179 24457417 8642276
B2M PTPRC â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 10358761 10559964 11154916 11509172 11717192 14508489 16181333 22076556 22790179 24457417 8642276
B2M LCK â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 10358761 10559964 11154916 11509172 11717192 14508489 16181333 22076556 22790179 24457417 8642276
GNB1 GNG2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 23739333 8636150 9789084 10339615 12606627 15889144 15782186 11294873 18611381 10696571 19376773 12782285 19168127
GNG2 GNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 23739333 8636150 9789084 10339615 12606627 15889144 15782186 11294873 18611381 10696571 19376773 12782285 19168127
CD4 TRAC â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
TRAC CD1A â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 18037897 26300885 15864273 14764708 20080535 15723809 7542404 21167756 22006319 25703557
TRAC HLA-DPA1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
TRAC HLA-DRA â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
TRAC LCK â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
TRAC CD1C â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 18037897 26300885 15864273 14764708 20080535 15723809 7542404 21167756 22006319 25703557
TRAC HLA-DQA2 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
TRAC CD1B â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 18037897 26300885 15864273 14764708 20080535 15723809 7542404 21167756 22006319 25703557
TRAC CD1D â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 18037897 26300885 15864273 14764708 20080535 15723809 7542404 21167756 22006319 25703557
TRAC HLA-DQA1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
TRAC PTPRJ â—¼   DEPHOSPHORYLATION ✅ 5.0 1.0 Reactome 20346773 23580664 11827988 21543337 2530588
TRAC PTPN6 â—¼   DEPHOSPHORYLATION ✅ 4.0 1.0 Reactome 12947224 15358536 18173375 18759926
TRAC PTPRC â—¼   DEPHOSPHORYLATION ✅ 5.0 1.0 Reactome 20346773 23580664 11827988 21543337 2530588
TRAC PTPN11 â—¼   DEPHOSPHORYLATION ✅ 4.0 1.0 Reactome 12947224 15358536 18173375 18759926
TRAV29DV5 PTPN11 â—¼   DEPHOSPHORYLATION ✅ 4.0 1.0 Reactome 12947224 15358536 18173375 18759926
TRAV29DV5 LCK â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
CD4 TRAV29DV5 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
HLA-DRA TRAV29DV5 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
HLA-DQA2 TRAV29DV5 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
TRAV29DV5 PTPRJ â—¼   DEPHOSPHORYLATION ✅ 5.0 1.0 Reactome 20346773 23580664 11827988 21543337 2530588
TRAV29DV5 CD1A â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 18037897 26300885 15864273 14764708 20080535 15723809 7542404 21167756 22006319 25703557
TRAV29DV5 CD1D â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 18037897 26300885 15864273 14764708 20080535 15723809 7542404 21167756 22006319 25703557
HLA-DQA1 TRAV29DV5 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
TRAV29DV5 PTPN6 â—¼   DEPHOSPHORYLATION ✅ 4.0 1.0 Reactome 12947224 15358536 18173375 18759926
TRAV29DV5 PTPRC â—¼   DEPHOSPHORYLATION ✅ 5.0 1.0 Reactome 20346773 23580664 11827988 21543337 2530588
TRAV29DV5 HLA-DPA1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
TRAV29DV5 CD1B â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 18037897 26300885 15864273 14764708 20080535 15723809 7542404 21167756 22006319 25703557
TRAV29DV5 CD1C â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 18037897 26300885 15864273 14764708 20080535 15723809 7542404 21167756 22006319 25703557
CD4 TRBC1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
TRBC1 HLA-DRA â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
TRBC1 CD1C â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 18037897 26300885 15864273 14764708 20080535 15723809 7542404 21167756 22006319 25703557
TRBC1 HLA-DQA2 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
TRBC1 HLA-DQA1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
TRBC1 CD1B â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 18037897 26300885 15864273 14764708 20080535 15723809 7542404 21167756 22006319 25703557
TRBC1 LCK â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
TRBC1 HLA-DPA1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
TRBC1 CD1A â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 18037897 26300885 15864273 14764708 20080535 15723809 7542404 21167756 22006319 25703557
TRBC1 CD1D â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 18037897 26300885 15864273 14764708 20080535 15723809 7542404 21167756 22006319 25703557
TRBC1 PTPRJ â—¼   DEPHOSPHORYLATION ✅ 5.0 1.0 Reactome 20346773 23580664 11827988 21543337 2530588
TRBC1 PTPRC â—¼   DEPHOSPHORYLATION ✅ 5.0 1.0 Reactome 20346773 23580664 11827988 21543337 2530588
TRBC1 PTPN11 â—¼   DEPHOSPHORYLATION ✅ 4.0 1.0 Reactome 12947224 15358536 18173375 18759926
TRBC1 PTPN6 â—¼   DEPHOSPHORYLATION ✅ 4.0 1.0 Reactome 12947224 15358536 18173375 18759926
AMFR VCP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 20126661 22328510 16407162 16987818 17681147 26712280 16275660 21636303 17872946 18835813 19828134 22119785 23333620 23383273 26424800 21343306 21914798 16186510 15331598 17311810
GRB2 CBL â—¼   PHYSICAL_INTERACTION 1.0 1.0 HIPPIE 25036637 25872741 8950973 917890 7642581 17944804 15210722 9108392 20936779 8695851 19836242 14725908 169092 28514442 9541596 9174058 11823423 12941616 10829062 10570290 7544353 11792427 8083187 15677445 8621719 9233773 9311917 23799367 16713569 10086340 9234717 8995358 25814554 9716598 11997436 7791764 8943292 8063801 8995445 8662998 11263968 16906159 8626404 9129019 98621719 17072306 9242692 10521482 9872323 8647120 7592693 9092538 10025673 17971399 17094785 9851874 11399323 33961781 9259313 18273061 7537740 8649804 9295052 11964172 9367879 20124286 10204582 19380743 9434624 21706016 8900205 9178909 12839496 9461587 31980649 11133830 33627783 8824292 8621483
GRB2 CBL â—¼   ENZYMATIC_REACTION ✅ 26.0 1.0 ACSN 10086337 10426994 10567412 10811803 10982827 11447289 11777939 11777960 11907067 12175651 12640133 15536084 15567848 15574420 16339513 16582911 16713974 16887996 17070508 17100878 17496910 17673906 18490724 19449109 26552706 8551221
CBL VAV1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 11353765 15169881 18835194 20189481
CBL CD247 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 11353765 15169881 18835194 20189481
CBL ZAP70 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 11353765 15169881 18835194 20189481
FYN CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 97.0 1.0 Omnipath 9525940 7642581 8626543 7782294 15208330 16503409 16713569 10829062 10799548 10934191 8900205 8551236 8662998 8995358 19734451 12604776 9890970 10592173 17570479 10629042 17094785 10092522 11997497 12522270 15556646 12244174 8621719 9102067 22880054 9311917 11239464 19904769 11994282 12941616 9535867 25814554 12231245 15190072
VAV1 CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 19635790 20940296 16289966 23331499 16356860 11133830 23180781 11331248 12881521 18835194 9200440 16713569 11313921
PTPN22 CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 10068674
LCK CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 9525940 10829062 10799548 10934191 7721825 16107303 12604776 9890970 17570479 11904433 9178909 10092522 11997497 12522270 8621719 9102067 11239464 11994282 11741956
CBL ZAP70 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 29.0 1.0 Omnipath 11133830 10779765 10358158 16503409 8798643 20189481 22266821 23109003 18835194 10074432 10078535 15268851 15169881 26192618 9407100 9988730 11353765
CBL PLCG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 30.0 1.0 Omnipath 7517397 9712732 12941616 25241761 12061819 23109003 9234717 16503409 11709089 16713569 17372230 16467851 12803489
CBL GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 158.0 1.0 Omnipath 11823423 8621483 9242692 18273061 17635922 16906159 8626404 8662998 9108392 9541596 98621719 9295052 25872741 17372273 8824292 8943292 12941616 20124286 19531499 10086340 8063801 9129019 9590251 11263968 9461587 7642581 10521482 10204582 8995445 8900205 7592693 9716598 8083187 14725908 17904548 7791764 9178909 25036637 8695851 19836242 7537740 15210722 9108316 169092 9311917 10514377 9092538 17072306 19380743 9872323 9234717 11997436 23799367 9434624 16713569 10829062 9367879 11964172 12839496 15677445 9851874 11792427 17094785 20936779 10570290 917890 17944804 25814554 17971399 11133830 8950973 21706016 8995358 9233773 10025673 8621719 11399323 9259313 9174058 8649804
CBL PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 98.0 1.0 Omnipath 9092574 19190244 16289966 11406619 7642581 11133830 10358153 8941725 9234717 8612729 11157475 10620516 16713569 21203488 11418612 24113870 17635922 18374639 14530346 11526404 8662998 8995358 11030146 9890970 9541596 11042121 15581361 9890943 8080844 7791764 9178909 15107835 8995243 8695807 9988765 23109003 11944898 15556646 17237826 10025673 17722974 8621719 16135792 16107703 16219545 9461587 9160881 9414268 16982329 19861161 10514377 9918857 11087752 9092538 11994282 9259313 15790353 19531499 9174058 8702998 25814554 22315502 19380743 10918571 8896416
CD3D CD1A â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 18037897 26300885 15864273 14764708 20080535 15723809 7542404 21167756 22006319 25703557
CD1A CD247 â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 18037897 26300885 15864273 14764708 20080535 15723809 7542404 21167756 22006319 25703557
CD1A CD3G â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 18037897 26300885 15864273 14764708 20080535 15723809 7542404 21167756 22006319 25703557
CD1A CD3E â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 18037897 26300885 15864273 14764708 20080535 15723809 7542404 21167756 22006319 25703557
CD3G CD1B â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 18037897 26300885 15864273 14764708 20080535 15723809 7542404 21167756 22006319 25703557
CD3D CD1B â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 18037897 26300885 15864273 14764708 20080535 15723809 7542404 21167756 22006319 25703557
CD3E CD1B â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 18037897 26300885 15864273 14764708 20080535 15723809 7542404 21167756 22006319 25703557
CD247 CD1B â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 18037897 26300885 15864273 14764708 20080535 15723809 7542404 21167756 22006319 25703557
CD247 CD1C â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 18037897 26300885 15864273 14764708 20080535 15723809 7542404 21167756 22006319 25703557
CD3E CD1C â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 18037897 26300885 15864273 14764708 20080535 15723809 7542404 21167756 22006319 25703557
CD3D CD1C â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 18037897 26300885 15864273 14764708 20080535 15723809 7542404 21167756 22006319 25703557
CD3G CD1C â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 18037897 26300885 15864273 14764708 20080535 15723809 7542404 21167756 22006319 25703557
CD3G CD1D â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 18037897 26300885 15864273 14764708 20080535 15723809 7542404 21167756 22006319 25703557
CD3D CD1D â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 18037897 26300885 15864273 14764708 20080535 15723809 7542404 21167756 22006319 25703557
CD3E CD1D â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 18037897 26300885 15864273 14764708 20080535 15723809 7542404 21167756 22006319 25703557
CD1D CD247 â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 18037897 26300885 15864273 14764708 20080535 15723809 7542404 21167756 22006319 25703557
HLA-DQA1 CD247 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
HLA-DRA CD247 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
CD4 CD247 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
HLA-DPA1 CD247 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
HLA-DQA2 CD247 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
CD247 ZAP70 â—¼   PHYSICAL_INTERACTION 36.0 1.0 ACSN 10358164 10562324 10925299 11353765 11438547 11449354 11875494 12393695 12415267 12731048 12811837 15081523 15099567 15735648 16713974 17371980 18768831 20435894 20814939 21059766 2139103 23414611 23508573 23620508 23886063 24378531 24445665 7523143 7600293 8344348 8478617 8551221 8642247 9603467 9625766 9738502
CD247 ZAP70 â—¼   SHARES_COMPLEX 36.0 1.0 ACSN 10358164 10562324 10925299 11353765 11438547 11449354 11875494 12393695 12415267 12731048 12811837 15081523 15099567 15735648 16713974 17371980 18768831 20435894 20814939 21059766 2139103 23414611 23508573 23620508 23886063 24378531 24445665 7523143 7600293 8344348 8478617 8551221 8642247 9603467 9625766 9738502
FYN CD247 â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 10591186 10648627 11062502 12218089 12731048 15536084 19290918 19909365 20814939 21378271 22683124 22863785 24440149 27192565 9738502
LCK CD247 â—¼   ENZYMATIC_REACTION ✅ 16.0 1.0 ACSN 10652356 11062502 12731048 12740575 15536084 17544292 19290918 20814939 21127503 22513334 23620508 8478617 8986721 9438848 9738502 9751747
CD4 CD247 â—¼   ENZYMATIC_REACTION ✅ 16.0 1.0 ACSN 10398592 10652356 12731048 12740575 17544292 19290918 20814939 21127503 22513334 23620508 3263576 8478617 8986721 9438848 9738502 9751747
PTPN11 CD247 â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 10358138 10849428 10982827 11447289 11572860 12138178 12640133 12707331 15240681 15699106 15713798 16212621 19833085 19909365 9751747
CD247 GRB2 â—¼   ENZYMATIC_REACTION ✅ 24.0 1.0 ACSN 10562324 10925299 11353765 11438547 11875494 12415267 12731048 12811837 15735648 16713974 17371980 20435894 20814939 21059766 23414611 23508573 23620508 23886063 24378531 7600293 8478617 8642247 9625766 9738502
CD247 ZAP70 â—¼   ENZYMATIC_REACTION ✅ 36.0 1.0 ACSN 10358164 10562324 10925299 11353765 11438547 11449354 11875494 12393695 12415267 12731048 12811837 15081523 15099567 15735648 16713974 17371980 18768831 20435894 20814939 21059766 2139103 23414611 23508573 23620508 23886063 24378531 24445665 7523143 7600293 8344348 8478617 8551221 8642247 9603467 9625766 9738502
CD247 SHC1 â—¼   ENZYMATIC_REACTION ✅ 21.0 1.0 ACSN 10358164 10562324 11353765 11449354 12393695 12731048 15081523 15099567 18768831 20814939 21059766 2139103 23414611 24445665 7523143 8344348 8478617 8551221 9603467 9625766 9738502
CD247 PLCG1 â—¼   ENZYMATIC_REACTION ✅ 24.0 1.0 ACSN 10562324 10925299 11353765 11438547 11875494 12415267 12731048 12811837 15735648 16713974 17371980 20435894 20814939 21059766 23414611 23508573 23620508 23886063 24378531 7600293 8478617 8642247 9625766 9738502
CD247 IL2 â—¼   ENZYMATIC_REACTION ✅ 12.0 1.0 ACSN 10562324 11062502 11353765 11385609 12731048 15536084 20814939 21059766 23414611 8478617 9625766 9738502
CD247 PTPRC â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 12414720 19290918 23620508 23886063 25312647
CD247 LCP2 â—¼   ENZYMATIC_REACTION ✅ 24.0 1.0 ACSN 10562324 10925299 11353765 11438547 11875494 12415267 12731048 12811837 15735648 16713974 17371980 20435894 20814939 21059766 23414611 23508573 23620508 23886063 24378531 7600293 8478617 8642247 9625766 9738502
CD247 LAT â—¼   ENZYMATIC_REACTION ✅ 24.0 1.0 ACSN 10562324 10925299 11353765 11438547 11875494 12415267 12731048 12811837 15735648 16713974 17371980 20435894 20814939 21059766 23414611 23508573 23620508 23886063 24378531 7600293 8478617 8642247 9625766 9738502
PTPRC CD247 â—¼   DEPHOSPHORYLATION ✅ 5.0 1.0 Reactome 20346773 23580664 11827988 21543337 2530588
CD247 PTPN11 â—¼   DEPHOSPHORYLATION ✅ 4.0 1.0 Reactome 12947224 15358536 18173375 18759926
CD247 PTPRJ â—¼   DEPHOSPHORYLATION ✅ 5.0 1.0 Reactome 20346773 23580664 11827988 21543337 2530588
CD247 PTPN6 â—¼   DEPHOSPHORYLATION ✅ 4.0 1.0 Reactome 12947224 15358536 18173375 18759926
LCK CD247 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 9047237 19229850 23109003 16461343 1706070 1505025 16337488 17979845 8626561
PTPN22 CD247 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 16461343
PTPN6 CD247 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 14672952 11238643 23109003
FYN CD247 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 8578591 12522270 7589084 9677202 9047237 15144186 1454062 1530920 15592455 16094384 9368621 16713569 96108162 15659558 8760790
CD247 ZAP70 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 74.0 1.0 Omnipath 11449354 10752619 8906806 18768831 2139103 8551221 23886063 9185620 12415267 10358158 10704231 8648092 7528772 7737297 11875494 15832366 15081523 24445665 9603467 17371980 21957439 8344348 7600293 7509083 7523143 15099567 10925299 9625766 8642247 9036949 8901551 16189514 21059766 9738502 12393695 24378531 20814939 23109003 9295038 8366117 11438547 26390156 23414611 23620508 8478617 20435894 7761456 15268851 16713974 26192618 12731048 10562324 20637659 7522230 12811837 11353765 23508573 10358164 15735648
GRB2 CD28 â—¼   PHYSICAL_INTERACTION 23.0 1.0 ACSN 10086337 10209041 10567412 10811803 10982827 11447289 11777939 12175651 12640133 1313950 15197224 15567848 15574420 16582911 16887996 17496910 17673906 19449109 22437870 26552706 7523569 8551221 9359474
GRB2 CD28 â—¼   SHARES_COMPLEX 23.0 1.0 ACSN 10086337 10209041 10567412 10811803 10982827 11447289 11777939 12175651 12640133 1313950 15197224 15567848 15574420 16582911 16887996 17496910 17673906 19449109 22437870 26552706 7523569 8551221 9359474
CD86 CD28 â—¼   ENZYMATIC_REACTION ✅ 19.0 1.0 ACSN 10477595 11207245 11964292 14764699 15034038 15197224 17513775 20231889 20805416 21220452 22076556 22437870 23390297 24218453 25215878 25384214 7523569 8920882 9359474
FYN CD28 â—¼   ENZYMATIC_REACTION ✅ 13.0 1.0 ACSN 10591186 10648627 12218089 12731048 19290918 19909365 20814939 21378271 22683124 22863785 24440149 27192565 9738502
CD80 CD28 â—¼   ENZYMATIC_REACTION ✅ 16.0 1.0 ACSN 11964292 12810107 14764699 15197224 17513775 17629517 18585785 20231889 22437870 23390297 25215878 25582338 26405600 7512027 7523569 9359474
CD28 LCP2 â—¼   ENZYMATIC_REACTION ✅ 23.0 1.0 ACSN 10086337 10209041 10567412 10811803 10982827 11447289 11777939 12175651 12640133 1313950 15197224 15567848 15574420 16582911 16887996 17496910 17673906 19449109 22437870 26552706 7523569 8551221 9359474
CD28 IL2 â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 ACSN 10426994 11907067 1313950 15197224 15536084 16713974 22437870 7523569 9359474
CD28 VAV1 â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 ACSN 10426994 11907067 1313950 15197224 15536084 16713974 22437870 7523569 9359474
LCK CD28 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 7568038 22936936 27460989 16094384 10430626 8992971
CD80 CD28 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 21530327 7964482 22437870 2164219 1847722 23954143 15610849 7545666 21982860 21487479
ITK CD28 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 19901323 10586033 22936936 8946678 15144186 15592455 16094384 8992971
CD86 CD28 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 21530327 22437870 18205792 23954143 11021528 21931534 21487479 7513726
CD28 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 18829987 8576157 9694876 24098653 27927989 21487479 7737275
HLA-DRA CD3D â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
HLA-DQA2 CD3D â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
CD4 CD3D â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
HLA-DQA1 CD3D â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
CD3D LCK â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
CD3D HLA-DPA1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
CD3D PTPRJ â—¼   DEPHOSPHORYLATION ✅ 5.0 1.0 Reactome 20346773 23580664 11827988 21543337 2530588
CD3D PTPN6 â—¼   DEPHOSPHORYLATION ✅ 4.0 1.0 Reactome 12947224 15358536 18173375 18759926
CD3D PTPN11 â—¼   DEPHOSPHORYLATION ✅ 4.0 1.0 Reactome 12947224 15358536 18173375 18759926
CD3D PTPRC â—¼   DEPHOSPHORYLATION ✅ 5.0 1.0 Reactome 20346773 23580664 11827988 21543337 2530588
HLA-DQA2 CD3E â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
CD4 CD3E â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
HLA-DRA CD3E â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
HLA-DQA1 CD3E â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
CD3E HLA-DPA1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
CD3E PTPN6 â—¼   DEPHOSPHORYLATION ✅ 4.0 1.0 Reactome 12947224 15358536 18173375 18759926
CD3E PTPRJ â—¼   DEPHOSPHORYLATION ✅ 5.0 1.0 Reactome 20346773 23580664 11827988 21543337 2530588
CD3E PTPN11 â—¼   DEPHOSPHORYLATION ✅ 4.0 1.0 Reactome 12947224 15358536 18173375 18759926
CD3E PTPRC â—¼   DEPHOSPHORYLATION ✅ 5.0 1.0 Reactome 20346773 23580664 11827988 21543337 2530588
LCK CD3E â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 12522270 2470098 15144186 11855827 15592455 16094384 15659558
CD3E ZAP70 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 7761456 8906806 21900181 8366117 11855827 9698567 17617578
CD3E PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9312149 11855827 11689561
HLA-DQA1 CD3G â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
CD4 CD3G â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
HLA-DRA CD3G â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
LCK CD3G â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
HLA-DQA2 CD3G â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
CD3G HLA-DPA1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
PTPRC CD3G â—¼   DEPHOSPHORYLATION ✅ 5.0 1.0 Reactome 20346773 23580664 11827988 21543337 2530588
CD3G PTPN11 â—¼   DEPHOSPHORYLATION ✅ 4.0 1.0 Reactome 12947224 15358536 18173375 18759926
CD3G PTPRJ â—¼   DEPHOSPHORYLATION ✅ 5.0 1.0 Reactome 20346773 23580664 11827988 21543337 2530588
CD3G PTPN6 â—¼   DEPHOSPHORYLATION ✅ 4.0 1.0 Reactome 12947224 15358536 18173375 18759926
LCK CD4 â—¼   PHYSICAL_INTERACTION 16.0 1.0 ACSN 10398592 10652356 12731048 12740575 17544292 19290918 20814939 21127503 22513334 23620508 3263576 8478617 8986721 9438848 9738502 9751747
CD4 HLA-DQA1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
CD4 HLA-DPA1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
CD4 HLA-DQA2 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
CD4 ITK â—¼   ENZYMATIC_REACTION ✅ 16.0 1.0 ACSN 10398592 10652356 12731048 12740575 17544292 19290918 20814939 21127503 22513334 23620508 3263576 8478617 8986721 9438848 9738502 9751747
CD4 PRKCQ â—¼   ENZYMATIC_REACTION ✅ 16.0 1.0 ACSN 10398592 10652356 12731048 12740575 17544292 19290918 20814939 21127503 22513334 23620508 3263576 8478617 8986721 9438848 9738502 9751747
CD4 VAV1 â—¼   ENZYMATIC_REACTION ✅ 16.0 1.0 ACSN 10398592 10652356 12731048 12740575 17544292 19290918 20814939 21127503 22513334 23620508 3263576 8478617 8986721 9438848 9738502 9751747
CD4 PTPRC â—¼   ENZYMATIC_REACTION ✅ 16.0 1.0 ACSN 10398592 10652356 12731048 12740575 17544292 19290918 20814939 21127503 22513334 23620508 3263576 8478617 8986721 9438848 9738502 9751747
CD4 ZAP70 â—¼   ENZYMATIC_REACTION ✅ 16.0 1.0 ACSN 10398592 10652356 12731048 12740575 17544292 19290918 20814939 21127503 22513334 23620508 3263576 8478617 8986721 9438848 9738502 9751747
CD4 PTPN6 â—¼   DEPHOSPHORYLATION ✅ 4.0 1.0 Reactome 12947224 15358536 18173375 18759926
CD4 PTPRJ â—¼   DEPHOSPHORYLATION ✅ 5.0 1.0 Reactome 20346773 23580664 11827988 21543337 2530588
CD4 PTPRC â—¼   DEPHOSPHORYLATION ✅ 5.0 1.0 Reactome 20346773 23580664 11827988 21543337 2530588
CD4 PTPN11 â—¼   DEPHOSPHORYLATION ✅ 4.0 1.0 Reactome 12947224 15358536 18173375 18759926
CD4 LCK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 16888650 8104794 11854499 8246987 3262426 12601806 17653867 23109003 12007789 16189514 17005671 15489916 15047060
CD80 CD86 â—¼   PHYSICAL_INTERACTION 25.0 1.0 ACSN 10477595 11207245 11964292 12810107 14764699 15034038 15197224 17513775 17629517 18585785 20231889 20805416 21220452 22076556 22437870 23390297 24218453 25215878 25384214 25582338 26405600 7512027 7523569 8920882 9359474
FYN CD80 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 9822663 15886116 10849438 12670394
FYN CD86 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 9822663 15886116 10849438 12670394
CD8A LAT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10562325
CD8A LCK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16818755 14500983 8814252
CREB1 IFNG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 20979795 11907114 20006311 12928400 16713974 22413812 7759501 12626576 9834094 15879136 20685939 18641343 9503023
CREB1 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 10471787 8647095 10403485 2140898
CREB1 IL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 11313407 12370343 17548609 12626549 15993752 12432566 8670878 8814256 11238674
JUN CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 2138276 1827203 18641343 8290251
ZAP70 DBNL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 14557276 16189514
DBNL MAP4K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10567356 14729663
ERLIN2 GRB2 â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 17505008 18757403 21666749 11689702 11739186 18381441 19809159 21160078 14534538 15448205
ERLIN2 PIK3R1 â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 17505008 18757403 21666749 11689702 11739186 18381441 19809159 21160078 14534538 15448205
ETS1 IL2RB â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 ACSN 15001984 15111329 15181457 16391805 17615296 21041997 21081489 22608498 9157999
ETS1 IL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 7876544 9780181 24019486
ETS1 FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9349499 8262053 1722028
JUN ETS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8557686 20195357
JUN FOS â—¼   PHYSICAL_INTERACTION 21.0 1.0 ACSN 10606235 11274345 11274400 14673140 15067049 16393692 16394015 17439715 18222063 18754863 19667062 19846528 21385848 21790308 22381618 22634314 22723415 23430059 26587781 8545107 9064320
FOS GRB2 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 11274345 12738796 15067049 16393692 16394015 18039929 19667062 21385848 22634314 23430059 9064320
JUN FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 2513130 14561487 8617996 8934539 19255142 9217081 12760745 2498806 10521486 8597411 10858536 12392213 9819441 1380150 23562910 1944274 9867253 9571041 1900040 2511006 14684847 15467742 12231642 11950097
FOS IFNG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 19285436 16713974 7759501 8756632 12842891 12432566
FOS IL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 20557936 8893011 11260070 11685114 8397339 1737937 9605137 9590239 11262396 7989759 1916630 8473495 10601992 8114694 22474330 18725523 9233628 11385624 2518655 15170389 8468462 7565732 12432566 8660843 7739550 1305903 20680391 19181930
FOS JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 73.0 1.0 Omnipath 20498278 16714286 21675959 25609649 23602568 9872330 20102225 8380166 18848838 18535250 2516828 8397339 15867431 18172215 9346889 10779323 9732876 16928824 26496610 15994313 22719067 24029232 16511568 20195357 11053448 20936779 26186194 18619508 20511396 16008525 10488148 21199371 8617242 17440114 16055710 15319445 11090181 9160889 23661758 1631061 15718494 11431474 31515488 8440710 7816143 20410304 34671206
LCK FYN â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 9822663 15886116 10849438 12670394
FYN PTPN11 â—¼   ENZYMATIC_REACTION ✅ 13.0 1.0 ACSN 10591186 10648627 12218089 12731048 19290918 19909365 20814939 21378271 22683124 22863785 24440149 27192565 9738502
FYN VAV1 â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 10591186 10648627 12218089 12731048 15699036 19290918 19909365 20814939 21378271 22683124 22863785 24440149 27192565 9738502 9822663
FYN GRB2 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 9822663 15886116 10849438 12670394
FYN PTPRC â—¼   ENZYMATIC_REACTION ✅ 17.0 1.0 ACSN 10591186 10648627 12218089 12414720 12731048 19290918 19909365 20814939 21378271 22683124 22863785 23620508 23886063 24440149 25312647 27192565 9738502
FYN PAG1 â—¼   ENZYMATIC_REACTION ✅ 13.0 1.0 ACSN 10591186 10648627 12218089 12731048 19290918 19909365 20814939 21378271 22683124 22863785 24440149 27192565 9738502
GRB2 FYN â—¼   DOWN_REGULATES ✅ - 52.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
SHC1 FYN â—¼   DOWN_REGULATES ✅ - 52.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
FYN IFNG â—¼   DOWN_REGULATES ✅ - 17.0 1.0 ACSN 10591186 10648627 12218089 12731048 16286920 19290918 19909365 20814939 20819927 21378271 22437870 22683124 22863785 24440149 27192565 28900677 9738502
PTPRC FYN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 1985196 8980254 11909961 1464315 1533589 9535845 16713569 9368621 12589038
FYN PTPN11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10212213 11157475 16713569
FYN LCP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10648627 9047237
FYN PRKCQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10383400 16713569
FYN VAV1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 11262396 15699036 11005864 9438848 16713569 15933714 9822663
FYN SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 96.0 1.0 Omnipath 19901323 20230923 16497976 9121430 15592455 16713569 9446569 17389395 23331499 18578522 10921922 10482988 10764799 18452278 20068231 10592173 18669648 12522270 9685404 10896916 7516469 9927207 12237775 8702728 8610109 19651622 9741627 9710204 19664994 17016520 10816433 11075717
FYN ZAP70 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 7760813 16713569 16839418
FYN PLCG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8395016 10586033 7682059 16713569
FYN PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 8294442 8394019 7515100 17570479 16713569 7520528 1652056
GRAP2 VAV1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11007481 8986718 10395673 9099726
GRB2 SHC1 â—¼   PHYSICAL_INTERACTION 69.0 1.0 ACSN 10022831 10086337 10358164 10567412 10811803 10849428 10982827 11166270 11283723 11335727 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15308668 15501236 15520864 15567848 15573129 15574420 15863030 16000375 16002046 16076871 16102570 16212621 16530705 16572188 16582911 16887996 17086423 17496910 17673906 17883421 18835194 19223473 19414323 19449109 19454690 19909365 21372296 21378271 22064427 22461508 22464172 23390297 23896411 24027568 24217602 24346288 24670066 25922287 26201938 26552706 7510700 8551221 8837607 9157999 9570538 9753319 9763606
GRB2 LAT â—¼   PHYSICAL_INTERACTION 51.0 1.0 ACSN 10072481 10086337 10209041 10567412 10781611 10811803 10925299 10982827 11169415 11447289 11532940 11777939 11994416 12175651 12640133 1281218 12845332 14764585 15214048 15567848 15574420 16102570 16329184 16582911 16887996 1712101 17397400 17496910 17673906 19449109 19494291 19909365 23523669 23620508 24584707 25137453 2536067 25456276 25960930 26552706 7523143 7682895 7890616 8226994 8551221 8649391 8976179 8995379 9489702 9535722 9846483
GRB2 PLCG1 â—¼   PHYSICAL_INTERACTION 51.0 1.0 ACSN 10072481 10086337 10209041 10567412 10781611 10811803 10925299 10982827 11169415 11447289 11532940 11777939 11994416 12175651 12640133 1281218 12845332 14764585 15214048 15567848 15574420 16102570 16329184 16582911 16887996 1712101 17397400 17496910 17673906 19449109 19494291 19909365 23523669 23620508 24584707 25137453 2536067 25456276 25960930 26552706 7523143 7682895 7890616 8226994 8551221 8649391 8976179 8995379 9489702 9535722 9846483
GRB2 PLCG1 â—¼   SHARES_COMPLEX 51.0 1.0 ACSN 10072481 10086337 10209041 10567412 10781611 10811803 10925299 10982827 11169415 11447289 11532940 11777939 11994416 12175651 12640133 1281218 12845332 14764585 15214048 15567848 15574420 16102570 16329184 16582911 16887996 1712101 17397400 17496910 17673906 19449109 19494291 19909365 23523669 23620508 24584707 25137453 2536067 25456276 25960930 26552706 7523143 7682895 7890616 8226994 8551221 8649391 8976179 8995379 9489702 9535722 9846483
PTPN11 GRB2 â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 ACSN 10358138 11447289 11572860 12138178 12707331 15240681 15699106 15713798 19833085 9751747
ZAP70 GRB2 â—¼   ENZYMATIC_REACTION ✅ 24.0 1.0 ACSN 10562324 10925299 11353765 11438547 11875494 12415267 12731048 12811837 15735648 16713974 17371980 20435894 20814939 21059766 23414611 23508573 23620508 23886063 24378531 7600293 8478617 8642247 9625766 9738502
LCK GRB2 â—¼   ENZYMATIC_REACTION ✅ 16.0 1.0 ACSN 10652356 11062502 12731048 12740575 15536084 17544292 19290918 20814939 21127503 22513334 23620508 8478617 8986721 9438848 9738502 9751747
ITK GRB2 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 11406363 12186560 15661896 25137453
JUN GRB2 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 11274345 12738796 17439715 18039929 26587781 8545107
GRB2 VAV1 â—¼   ENZYMATIC_REACTION ✅ 57.0 1.0 ACSN 10077632 10086337 10426994 10567412 10646608 10679059 10714681 10811803 10849438 10898494 10982827 11080163 11447289 11526404 11698448 11754814 11777939 11777960 11907067 11994416 12094222 12165654 12175651 12186560 12616499 12626562 12640133 12740575 12885870 12917349 14764585 15169881 15536084 15567848 15574420 16339513 16582911 16713974 16887996 17070508 17100878 17496910 17673906 18490724 19449109 19909365 20189481 22513334 22786724 22952938 25355530 25539813 26552706 8189062 8226994 8551221 9438848
GRB2 PIK3R1 â—¼   ENZYMATIC_REACTION ✅ 32.0 1.0 ACSN 10086337 10567412 10811803 10849428 10982827 11335727 11447289 11449354 11532940 11777939 12175651 12393695 12640133 15308668 15567848 15574420 16000375 16076871 16530705 16582911 16887996 17496910 17673906 18835194 19449109 19454690 22064427 22464172 24217602 25922287 26552706 8551221
GRB2 PLCG1 â—¼   ENZYMATIC_REACTION ✅ 51.0 1.0 ACSN 10072481 10086337 10209041 10567412 10781611 10811803 10925299 10982827 11169415 11447289 11532940 11777939 11994416 12175651 12640133 1281218 12845332 14764585 15214048 15567848 15574420 16102570 16329184 16582911 16887996 1712101 17397400 17496910 17673906 19449109 19494291 19909365 23523669 23620508 24584707 25137453 2536067 25456276 25960930 26552706 7523143 7682895 7890616 8226994 8551221 8649391 8976179 8995379 9489702 9535722 9846483
GRB2 LAT â—¼   ENZYMATIC_REACTION ✅ 51.0 1.0 ACSN 10072481 10086337 10209041 10567412 10781611 10811803 10925299 10982827 11169415 11447289 11532940 11777939 11994416 12175651 12640133 1281218 12845332 14764585 15214048 15567848 15574420 16102570 16329184 16582911 16887996 1712101 17397400 17496910 17673906 19449109 19494291 19909365 23523669 23620508 24584707 25137453 2536067 25456276 25960930 26552706 7523143 7682895 7890616 8226994 8551221 8649391 8976179 8995379 9489702 9535722 9846483
GRB2 SHC1 â—¼   ENZYMATIC_REACTION ✅ 69.0 1.0 ACSN 10022831 10086337 10358164 10567412 10811803 10849428 10982827 11166270 11283723 11335727 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15308668 15501236 15520864 15567848 15573129 15574420 15863030 16000375 16002046 16076871 16102570 16212621 16530705 16572188 16582911 16887996 17086423 17496910 17673906 17883421 18835194 19223473 19414323 19449109 19454690 19909365 21372296 21378271 22064427 22461508 22464172 23390297 23896411 24027568 24217602 24346288 24670066 25922287 26201938 26552706 7510700 8551221 8837607 9157999 9570538 9753319 9763606
GRB2 LCP2 â—¼   ENZYMATIC_REACTION ✅ 26.0 1.0 ACSN 10086337 10426994 10567412 10811803 10982827 11447289 11777939 11777960 11907067 12175651 12640133 15536084 15567848 15574420 16339513 16582911 16713974 16887996 17070508 17100878 17496910 17673906 18490724 19449109 26552706 8551221
LAT GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 11368773 9489702 10811803 8063801 17043143 16938345 16713569 23150273 12186560 16906159
VAV1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 32.0 1.0 Omnipath 8900182 10207103 9013873 15558030 7651724 7809090 8621483 29997244 18692475 7478592 16713569 11406576 9209406 16339550
LCP2 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 7706237 20936779 10224278 8695800 17235283 15929943 25416956 19380743 9716598 32296183 10204582 11314042 8995445
SHC1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 198.0 1.0 Omnipath 8808684 9083103 8551221 9126968 8621483 25416956 9252386 8524223 7535773 8662998 11302736 11827484 8995379 9541596 9175774 10207047 7717978 17673906 7744881 11505033 10523831 24189400 9927207 7650032 8810340 9045692 23178716 19531499 15812354 9129019 10356320 12485888 9461587 8114695 7514169 9566877 8939605 16371368 15341520 7529871 10891441 10749687 7524086 26645482 8491186 10592173 10049786 9171350 11707404 7537740 15688026 8663178 19380743 11782427 9544989 16436051 9434624 16713569 21725358 11964172 17314098 11792427 8195171 1465135 12213123 8647288 12955078 10477741 11707405 12577067 9199344 10080542 8112292 7760801 10570290 11997181 7798267 16520382 10961885 8950973 21706016 9448048 8662733 11370743 8051109 9733714 8621475 9254595 8294403 10748054 8621719 8940013 12441060 22057045 7505797 24737791 20697350 9886492 18174162 18273058 8235613 7963520 7523859
PTPN11 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 66.0 1.0 Omnipath 8702859 9361008 16371368 21706016 8041791 11085989 8978300 11432792 15882975 9362449 10212213 11684012 7523381 10592173 16189514 10747947 10973965 9632781 8959326 11602579 12577067 9254654 10080542 15010462 31585087 12531430 8995399 19380743 7522233 9804835 7534299 9824671 9660791
GRB2 MAP4K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 9346925 9891069 9788432 17474147 11279207
GRB2 PLCG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 9281317 15953601 7629168 9020117 16713569 10940929
LCK HLA-DPA1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
PTPRC HLA-DPA1 â—¼   DEPHOSPHORYLATION ✅ 5.0 1.0 Reactome 20346773 23580664 11827988 21543337 2530588
HLA-DPA1 PTPN6 â—¼   DEPHOSPHORYLATION ✅ 4.0 1.0 Reactome 12947224 15358536 18173375 18759926
HLA-DPA1 PTPN11 â—¼   DEPHOSPHORYLATION ✅ 4.0 1.0 Reactome 12947224 15358536 18173375 18759926
HLA-DPA1 PTPRJ â—¼   DEPHOSPHORYLATION ✅ 5.0 1.0 Reactome 20346773 23580664 11827988 21543337 2530588
HLA-DQA1 LCK â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
HLA-DQA1 PTPRC â—¼   DEPHOSPHORYLATION ✅ 5.0 1.0 Reactome 20346773 23580664 11827988 21543337 2530588
HLA-DQA1 PTPRJ â—¼   DEPHOSPHORYLATION ✅ 5.0 1.0 Reactome 20346773 23580664 11827988 21543337 2530588
HLA-DQA1 PTPN11 â—¼   DEPHOSPHORYLATION ✅ 4.0 1.0 Reactome 12947224 15358536 18173375 18759926
HLA-DQA1 PTPN6 â—¼   DEPHOSPHORYLATION ✅ 4.0 1.0 Reactome 12947224 15358536 18173375 18759926
HLA-DQA2 LCK â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
HLA-DQA2 PTPN11 â—¼   DEPHOSPHORYLATION ✅ 4.0 1.0 Reactome 12947224 15358536 18173375 18759926
HLA-DQA2 PTPRC â—¼   DEPHOSPHORYLATION ✅ 5.0 1.0 Reactome 20346773 23580664 11827988 21543337 2530588
HLA-DQA2 PTPN6 â—¼   DEPHOSPHORYLATION ✅ 4.0 1.0 Reactome 12947224 15358536 18173375 18759926
HLA-DQA2 PTPRJ â—¼   DEPHOSPHORYLATION ✅ 5.0 1.0 Reactome 20346773 23580664 11827988 21543337 2530588
HLA-DRA LCK â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
HLA-DRA PTPRC â—¼   DEPHOSPHORYLATION ✅ 5.0 1.0 Reactome 20346773 23580664 11827988 21543337 2530588
HLA-DRA PTPN11 â—¼   DEPHOSPHORYLATION ✅ 4.0 1.0 Reactome 12947224 15358536 18173375 18759926
HLA-DRA PTPRJ â—¼   DEPHOSPHORYLATION ✅ 5.0 1.0 Reactome 20346773 23580664 11827988 21543337 2530588
HLA-DRA PTPN6 â—¼   DEPHOSPHORYLATION ✅ 4.0 1.0 Reactome 12947224 15358536 18173375 18759926
JUN IFNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 9660935 18035482 22065573 10848607 20048166 22083261 17376932
PTPN6 IFNG â—¼   DOWN_REGULATES ✅ - 34.0 1.0 ACSN 10358138 11447289 11449354 11572860 12138178 12176909 1238444 12393695 12421919 12707331 12773515 12917349 15169881 15240681 15699106 15713798 16204085 19833085 20363967 20435894 21469115 22483603 22513334 22683124 22952938 22955274 25355530 26667266 26755705 27474009 8976179 8986721 9751747 9765283
PTPN11 IFNG â—¼   DOWN_REGULATES ✅ - 34.0 1.0 ACSN 10358138 11447289 11449354 11572860 12138178 12176909 1238444 12393695 12421919 12707331 12773515 12917349 15169881 15240681 15699106 15713798 16204085 19833085 20363967 20435894 21469115 22483603 22513334 22683124 22952938 22955274 25355530 26667266 26755705 27474009 8976179 8986721 9751747 9765283
JUN IFNG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 20006311 22123848 14734615 15187132 11943142 20304822 17556653 1314139 17105733 22413812 19265145 11801649 16713974 7759501 12836278 15522880 12626576 9558063 8756632 18641343 22351517
IKZF1 IL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 17148585 18025173 19828627 22684523 24328678
IL2 IL2RA â—¼   PHYSICAL_INTERACTION 26.0 1.0 ACSN 10807786 10820393 10849428 12095053 15289500 15563472 16212621 16799562 17371980 1825141 18758473 19528259 19833085 20856220 21840487 22224781 23124025 23650441 24829413 26755705 2965306 6164929 7512720 7521688 8683106 9625766
IL2 IL2RG â—¼   PHYSICAL_INTERACTION 26.0 1.0 ACSN 10807786 10820393 10849428 12095053 15289500 15563472 16212621 16799562 17371980 1825141 18758473 19528259 19833085 20856220 21840487 22224781 23124025 23650441 24829413 26755705 2965306 6164929 7512720 7521688 8683106 9625766
IL2 IL2RB â—¼   PHYSICAL_INTERACTION 26.0 1.0 ACSN 10807786 10820393 10849428 12095053 15289500 15563472 16212621 16799562 17371980 1825141 18758473 19528259 19833085 20856220 21840487 22224781 23124025 23650441 24829413 26755705 2965306 6164929 7512720 7521688 8683106 9625766
IL2 IL2RB â—¼   SHARES_COMPLEX 26.0 1.0 ACSN 10807786 10820393 10849428 12095053 15289500 15563472 16212621 16799562 17371980 1825141 18758473 19528259 19833085 20856220 21840487 22224781 23124025 23650441 24829413 26755705 2965306 6164929 7512720 7521688 8683106 9625766
IL2 IL2RA â—¼   SHARES_COMPLEX 26.0 1.0 ACSN 10807786 10820393 10849428 12095053 15289500 15563472 16212621 16799562 17371980 1825141 18758473 19528259 19833085 20856220 21840487 22224781 23124025 23650441 24829413 26755705 2965306 6164929 7512720 7521688 8683106 9625766
IL2 IL2RG â—¼   SHARES_COMPLEX 26.0 1.0 ACSN 10807786 10820393 10849428 12095053 15289500 15563472 16212621 16799562 17371980 1825141 18758473 19528259 19833085 20856220 21840487 22224781 23124025 23650441 24829413 26755705 2965306 6164929 7512720 7521688 8683106 9625766
PTPN11 IL2 â—¼   DOWN_REGULATES ✅ - 26.0 1.0 ACSN 10358138 11447289 11449354 11572860 12138178 1238444 12393695 12421919 12707331 15169881 15240681 15699106 15713798 16204085 17307799 19406987 19479342 19833085 20363967 20435894 21469115 22483603 22683124 22955274 27557510 9751747
PTPN6 IL2 â—¼   DOWN_REGULATES ✅ - 34.0 1.0 ACSN 10358138 11447289 11449354 11572860 12138178 12176909 1238444 12393695 12421919 12707331 12773515 12917349 15169881 15240681 15699106 15713798 16204085 19833085 20363967 20435894 21469115 22483603 22513334 22683124 22952938 22955274 25355530 26667266 26755705 27474009 8976179 8986721 9751747 9765283
JUN IL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 20557936 12370343 10700231 12884855 8436291 9541574 8397339 1737937 9605137 8683110 21832163 9590239 7989759 9774418 16116194 8473495 8114694 10878360 10320367 9233628 7642615 17097050 7565732 8468462 8660843 7739550 8051409 1740667 19181930
IL2 IL2RG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 53.0 1.0 Omnipath 15265897 16477002 10807786 19528259 19833085 7521688 17371980 8049354 15563472 18758473 10662798 15289500 23331499 26755705 8683106 23180781 12095053 11418623 6164929 9625766 24829413 1825141 8006584 16799562 7829965 8568232 10820393 7512720 23650441 20856220 7681595 10849428 22224781 1631559 16212621 21840487 26192618 2965306 8260650 23124025
IL2 IL2RA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 6815536 3095922 15265897 12649439 16477002 15933202 1940342 17032757 15178252 8260650 3116143 8894436 1993646 8580082 8960125
IL2 IL2RB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 8568232 3095922 15265897 16477002 11035066 3098894 15933202 1940342 15178252 8260650 3116143 22446627 8006584 8049354
IL2RB IL2RA â—¼   PHYSICAL_INTERACTION 26.0 1.0 ACSN 10807786 10820393 10849428 12095053 15289500 15563472 16212621 16799562 17371980 1825141 18758473 19528259 19833085 20856220 21840487 22224781 23124025 23650441 24829413 26755705 2965306 6164929 7512720 7521688 8683106 9625766
IL2RG IL2RA â—¼   PHYSICAL_INTERACTION 26.0 1.0 ACSN 10807786 10820393 10849428 12095053 15289500 15563472 16212621 16799562 17371980 1825141 18758473 19528259 19833085 20856220 21840487 22224781 23124025 23650441 24829413 26755705 2965306 6164929 7512720 7521688 8683106 9625766
IL2RB IL2RA â—¼   SHARES_COMPLEX 26.0 1.0 ACSN 10807786 10820393 10849428 12095053 15289500 15563472 16212621 16799562 17371980 1825141 18758473 19528259 19833085 20856220 21840487 22224781 23124025 23650441 24829413 26755705 2965306 6164929 7512720 7521688 8683106 9625766
IL2RG IL2RA â—¼   SHARES_COMPLEX 26.0 1.0 ACSN 10807786 10820393 10849428 12095053 15289500 15563472 16212621 16799562 17371980 1825141 18758473 19528259 19833085 20856220 21840487 22224781 23124025 23650441 24829413 26755705 2965306 6164929 7512720 7521688 8683106 9625766
IL2RB IL2RA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 8568232 15265897 11886175 15933202 15178252 1545122 8260650 3116143 8006584
IL2RA IL2RG â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 15933202 15265897 8568232 8260650
IL2RG IL2RB â—¼   PHYSICAL_INTERACTION 36.0 1.0 ACSN 10807786 10820393 10849428 12095053 12811837 14607946 15289500 15563472 16212621 16799562 16815076 17371980 17398124 17459805 1825141 18758473 19528259 19833085 19913445 20007590 20856220 21307131 21840487 22224781 23124025 23650441 24829413 25582338 26755705 2965306 6164929 7512720 7521688 7523571 8683106 9625766
IL2RG IL2RB â—¼   SHARES_COMPLEX 36.0 1.0 ACSN 10807786 10820393 10849428 12095053 12811837 14607946 15289500 15563472 16212621 16799562 16815076 17371980 17398124 17459805 1825141 18758473 19528259 19833085 19913445 20007590 20856220 21307131 21840487 22224781 23124025 23650441 24829413 25582338 26755705 2965306 6164929 7512720 7521688 7523571 8683106 9625766
PTPN6 IL2RB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 9520455 9973481
LCK IL2RB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 10214954 2047859 10602027 18348982 16189514 12200137
IL2RG IL2RB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 8568232 15265897 7514277 10903799 11886175 8026467 15933202 7681595 15178252 1545122 8260650 16189514 11851401 8006584
IL2RB SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 8294403 8700888 8643566 10602027 16189514 24737791
IL2RB IL2RG â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 8568232 15265897 7514277 10903799 11886175 8026467 15933202 7681595 15178252 1545122 8260650 16189514 11851401 8006584
LCK ITK â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 10652356 12731048 12740575 17544292 19290918 20814939 21127503 22513334 23620508 3263576 8478617 8986721 9438848 9738502 9751747
ITK LAT â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 11406363 12186560 15661896 25137453
ITK PLCG1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 11406363 12186560 15661896 25137453
LCK ITK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 29.0 1.0 Omnipath 21747996 28516764 19132916 23109003 20305788 23982207 15771581 19690332 28644030 15144186 9312162 12842872 17192257 23946894
ITK LAT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 11368773 9489702 10506192 12186560
ITK PLCG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 44.0 1.0 Omnipath 24412752 15975899 22847294 20237289 15623534 19690332 12163161 23933134 30131370 15184383 16126727 12730118 31196981 17389395 23331499 19534553 20519342 16081816 15215251 17372230 17420479 27221712 17148460 21760611 12952950 25916191 19427038 27941787 10586033 34429382 23109003 11564877 12029091 12941616 19412549 14568990 28644030 11709089 8657103 15951569 22649724
PLCG1 LAT â—¼   PHYSICAL_INTERACTION 51.0 1.0 ACSN 10072481 10086337 10209041 10567412 10781611 10811803 10925299 10982827 11169415 11447289 11532940 11777939 11994416 12175651 12640133 1281218 12845332 14764585 15214048 15567848 15574420 16102570 16329184 16582911 16887996 1712101 17397400 17496910 17673906 19449109 19494291 19909365 23523669 23620508 24584707 25137453 2536067 25456276 25960930 26552706 7523143 7682895 7890616 8226994 8551221 8649391 8976179 8995379 9489702 9535722 9846483
PLCG1 LAT â—¼   SHARES_COMPLEX 51.0 1.0 ACSN 10072481 10086337 10209041 10567412 10781611 10811803 10925299 10982827 11169415 11447289 11532940 11777939 11994416 12175651 12640133 1281218 12845332 14764585 15214048 15567848 15574420 16102570 16329184 16582911 16887996 1712101 17397400 17496910 17673906 19449109 19494291 19909365 23523669 23620508 24584707 25137453 2536067 25456276 25960930 26552706 7523143 7682895 7890616 8226994 8551221 8649391 8976179 8995379 9489702 9535722 9846483
PLCG1 LAT â—¼   ENZYMATIC_REACTION ✅ 51.0 1.0 ACSN 10072481 10086337 10209041 10567412 10781611 10811803 10925299 10982827 11169415 11447289 11532940 11777939 11994416 12175651 12640133 1281218 12845332 14764585 15214048 15567848 15574420 16102570 16329184 16582911 16887996 1712101 17397400 17496910 17673906 19449109 19494291 19909365 23523669 23620508 24584707 25137453 2536067 25456276 25960930 26552706 7523143 7682895 7890616 8226994 8551221 8649391 8976179 8995379 9489702 9535722 9846483
ZAP70 LAT â—¼   ENZYMATIC_REACTION ✅ 8.0 1.0 ACSN 12415267 12731048 15735648 17371980 20814939 23620508 7600293 8642247
VAV1 LAT â—¼   ENZYMATIC_REACTION ✅ 33.0 1.0 ACSN 10077632 10646608 10679059 10714681 10849438 10898494 11080163 11526404 11698448 11754814 11994416 12094222 12165654 12186560 12616499 12626562 12740575 12885870 12917349 14764585 15169881 16887996 19909365 20189481 22513334 22786724 22952938 25355530 25539813 26552706 8189062 8226994 9438848
LAT SHC1 â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 ACSN 10072481 10781611 10811803 11169415 12640133 14764585 16102570 16329184 19494291 19909365 23620508 25137453 7523143 7890616 8649391 8976179 9489702 9535722
LAT LCP2 â—¼   ENZYMATIC_REACTION ✅ 51.0 1.0 ACSN 10072481 10086337 10209041 10567412 10781611 10811803 10925299 10982827 11169415 11447289 11532940 11777939 11994416 12175651 12640133 1281218 12845332 14764585 15214048 15567848 15574420 16102570 16329184 16582911 16887996 1712101 17397400 17496910 17673906 19449109 19494291 19909365 23523669 23620508 24584707 25137453 2536067 25456276 25960930 26552706 7523143 7682895 7890616 8226994 8551221 8649391 8976179 8995379 9489702 9535722 9846483
ZAP70 LAT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 24412752 15659558 10811803 27896837 11395491 15084594 16906159 15029250 27700984 12496416 34161759 11368773 30510001 23109003 22507872 18779373 33931484 23758320 15100278 24642916 23150273
LCK LAT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 16938345 12359715 12186560 27700984
PTPRJ LAT â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 11259588
LAT VAV1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 11368773 23109003 16713569 12186560
LAT PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11368773 9489702 19132916 23109003 16713569 14696041
LAT PLCG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 29.0 1.0 Omnipath 27221712 11368773 9489702 12941616 15286727 10811803 23109003 24642916 16938345 11709089 16713569 15219999 16467851 9729044
LCK PRKCQ â—¼   ENZYMATIC_REACTION ✅ 16.0 1.0 ACSN 10398592 10652356 12731048 12740575 17544292 19290918 20814939 21127503 22513334 23620508 3263576 8478617 8986721 9438848 9738502 9751747
LCK ZAP70 â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 10652356 12731048 12740575 17544292 19290918 20814939 21127503 22513334 23620508 3263576 8478617 8986721 9438848 9738502 9751747
LCK VAV1 â—¼   ENZYMATIC_REACTION ✅ 16.0 1.0 ACSN 10398592 10652356 12731048 12740575 17544292 19290918 20814939 21127503 22513334 23620508 3263576 8478617 8986721 9438848 9738502 9751747
LCK PTPRC â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 ACSN 10652356 12414720 12731048 12740575 17544292 19290918 20814939 21127503 22513334 23620508 23886063 25312647 3263576 8478617 8986721 9438848 9738502 9751747
LCK PTPRJ â—¼   DEPHOSPHORYLATION ✅ 5.0 1.0 Reactome 20346773 23580664 11827988 21543337 2530588
LCK PTPN6 â—¼   DEPHOSPHORYLATION ✅ 4.0 1.0 Reactome 12947224 15358536 18173375 18759926
LCK PTPN11 â—¼   DEPHOSPHORYLATION ✅ 4.0 1.0 Reactome 12947224 15358536 18173375 18759926
PAG1 LCK â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 22566970 27045023 14610046 10790433 20813252 24764511
PTPN22 LCK â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 16461343 16111633 19167335 21719704
PTPRC LCK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 31.0 1.0 Omnipath 17145710 19167335 8433999 2141684 9973453 8473339 2141630 12589038 8663450 15085197 2548204 8441403 11259588 15743820 10330160 2530588 10369126 8576115 7507203 11369760 17719247
LCK PRKCQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 22798961 26090489 17548359 10652356
LCK PTPN6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 36.0 1.0 Omnipath 23071622 8692915 16231973 23109003 14699166 19167335 12459785 12468540 11294838 10574931 7512963 16497976 16189514 14757045 8114715 10488096
LCK SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 74.0 1.0 Omnipath 19901323 20230923 16497976 9121430 15592455 9446569 17389395 18578522 10921922 10482988 10764799 18452278 20068231 18669648 12522270 9685404 10896916 9927207 12237775 8702728 8610109 19651622 9741627 9710204 19664994 17016520 10816433 11075717
LCK ZAP70 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 110.0 1.0 Omnipath 23874979 7961936 17579062 29073235 30992398 15292262 23933134 31932281 21829558 15592455 21917715 9199177 8798643 7612267 16339550 23331499 10202147 22238573 16189514 32184287 21103055 7642520 33531381 12648457 12522270 17998387 9685404 20945976 16839418 15144186 16461343 16094384 11270871 17192257 10037717 8756661 19606965 23758320 27869819 16111633 25137454 15268851 17942891 33482200 11514606 11514605 15659558 10556826 10318843
LCK PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 8294442 11337495 8246987 14583609 11526404 15032589 23109003 9461588 7504174 8397196 10488096
LCK VAV1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 20028078 24332539 898671 16285729 15708849 17050525 15699036 17570479 11005864 10669745 10636924
LCK LCP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 16354835 21725281 8702662 10648627 10556826
ZAP70 LCP2 â—¼   ENZYMATIC_REACTION ✅ 8.0 1.0 ACSN 12415267 12731048 15735648 17371980 20814939 23620508 7600293 8642247
PLCG1 LCP2 â—¼   ENZYMATIC_REACTION ✅ 51.0 1.0 ACSN 10072481 10086337 10209041 10567412 10781611 10811803 10925299 10982827 11169415 11447289 11532940 11777939 11994416 12175651 12640133 1281218 12845332 14764585 15214048 15567848 15574420 16102570 16329184 16582911 16887996 1712101 17397400 17496910 17673906 19449109 19494291 19909365 23523669 23620508 24584707 25137453 2536067 25456276 25960930 26552706 7523143 7682895 7890616 8226994 8551221 8649391 8976179 8995379 9489702 9535722 9846483
LCP2 PRKCQ â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 ACSN 12640133 19909365 20189481 21536650 22786724 23474202 23620508 24343663 24584089 9765283
LCP2 VAV1 â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 ACSN 12640133 19909365 20189481 21536650 22786724 23474202 23620508 24343663 24584089 9765283
PTPN6 LCP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 8760799 15588985 16189514 9765283 15668918
ZAP70 LCP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 35.0 1.0 Omnipath 12817019 9047237 15388330 10660534 15286727 23109003 8892604 12640133 12640123 11323691 8702662 23758320
MAP4K1 LCP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 21949020 17353368 28107427 22105350 11487585
LCP2 PLCG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 23331499 12941616 9341187 23109003 21725281 15929943 11709089 16467851 11390650
SHC1 PIK3R1 â—¼   ENZYMATIC_REACTION ✅ 32.0 1.0 ACSN 10086337 10567412 10811803 10849428 10982827 11335727 11447289 11449354 11532940 11777939 12175651 12393695 12640133 15308668 15567848 15574420 16000375 16076871 16530705 16582911 16887996 17496910 17673906 18835194 19449109 19454690 22064427 22464172 24217602 25922287 26552706 8551221
PTPN11 PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 11593409 18950707 15790353 23109003 16371368 17722974 22315502 16107703 9660791 9918857 8080844 9632795 10973965
PTPN6 PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 21780115 11337495 11526404 15032589 9065461 11160222 23109003 22880054 10488096
SHC1 PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 19531499 8662998 7537361 19380743 8621719 16135792 9541596 16219545 16713569 23397142 19889638
VAV1 PLCG1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11007481 8986718 10395673 9099726
SHC1 PLCG1 â—¼   ENZYMATIC_REACTION ✅ 52.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
VAV1 PLCG1 â—¼   ENZYMATIC_REACTION ✅ 33.0 1.0 ACSN 10077632 10646608 10679059 10714681 10849438 10898494 11080163 11526404 11698448 11754814 11994416 12094222 12165654 12186560 12616499 12626562 12740575 12885870 12917349 14764585 15169881 16887996 19909365 20189481 22513334 22786724 22952938 25355530 25539813 26552706 8189062 8226994 9438848
ZAP70 PLCG1 â—¼   ENZYMATIC_REACTION ✅ 24.0 1.0 ACSN 10562324 10925299 11353765 11438547 11875494 12415267 12731048 12811837 15735648 16713974 17371980 20435894 20814939 21059766 23414611 23508573 23620508 23886063 24378531 7600293 8478617 8642247 9625766 9738502
PTPRJ PLCG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 11259588
VAV1 PLCG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 67.0 1.0 Omnipath 11340169 10849438 22952938 9099726 12626562 12917349 12165654 16713569 25539813 8673706 19909365 7518558 10077632 11278486 26552706 10395673 12885870 12573241 8629002 11526404 10898494 25355530 17050525 10592173 11698448 10646608 11094073 11994416 20189481 12670394 9550384 12616499 22513334 10679059 23109003 9891995 11007481 12740575 17540168 11804587 8630736 17054426 11754814 8986718 9438848 11080163 29145629 12941616 10714681 14764585 15169881 26192618 22786724 8226994 15010370 12094222 8189062 16887996 11709089 16467851 24243840 12186560
VAV1 PRKCQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 23331499 11956228 23109003 10725744 15802604 14673152 21487479
PTPN11 PTPN6 â—¼   PHYSICAL_INTERACTION 42.0 1.0 ACSN 10358138 11447289 11449354 11572860 12138178 12176909 1238444 12393695 12421919 12707331 12773515 12917349 15169881 15240681 15699106 15713798 16204085 17371980 19833085 20007250 20038811 20363967 20435894 21469115 22437870 22483603 22513334 22683124 22952938 22955274 23732914 25355530 26667266 26755705 26885856 27474009 27806234 28893624 8976179 8986721 9751747 9765283
PTPN11 PTPN6 â—¼   SHARES_COMPLEX 42.0 1.0 ACSN 10358138 11447289 11449354 11572860 12138178 12176909 1238444 12393695 12421919 12707331 12773515 12917349 15169881 15240681 15699106 15713798 16204085 17371980 19833085 20007250 20038811 20363967 20435894 21469115 22437870 22483603 22513334 22683124 22952938 22955274 23732914 25355530 26667266 26755705 26885856 27474009 27806234 28893624 8976179 8986721 9751747 9765283
PTPN22 ZAP70 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 16461343 15659558
PTPN6 VAV1 â—¼   ENZYMATIC_REACTION ✅ 13.0 1.0 ACSN 12176909 12773515 12917349 15240681 15713798 22513334 22952938 25355530 26667266 27474009 8976179 8986721 9765283
PTPN6 VAV1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 8632004 10592173 16189514
PTPN6 ZAP70 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 12763134 23109003 8638162 23180781 16189514 10458769
ZAP70 SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 90.0 1.0 Omnipath 19901323 7961936 9388490 20230923 9096689 16497976 9121430 15592455 9446569 10891441 17389395 11687594 18578522 10921922 10482988 10764799 18452278 20068231 16189514 18669648 12522270 9685404 10896916 9927207 15688026 12237775 8702728 8610109 19651622 9741627 8761298 9710204 19664994 17016520 10816433 11075717
ZAP70 VAV1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 10395678 23109003 14757747 15751964 7798261 16189514 11859198 23758320 16339550