PTPN6
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
10660620
6671678
|
FYN
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
9694876
7737275
|
LCK
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
9694876
7737275
|
PIK3CA
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
GRB2
|
PPP3CA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5216105
12577067
|
GRB2
|
PPP3CB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
MAPK3
|
GRB2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
7739560
8816480
|
VAV1
|
GRB2
|
â—¼ PROXIMITY
|
|
|
2.0
|
0.8
|
intact
|
29997244
20178071
|
GRB2
|
PTPN11
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
17993263
15031289
|
RAF1
|
MAPK3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
20674547
15664191
|
FOS
|
MAPK3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
7588633
12134156
|
MAPK3
|
SOS1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
7739560
8816480
|
PRKCB
|
MAPK3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
8903320
10327068
|
MAPK3
|
RELA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16888388
16691505
|
NFATC2
|
NFATC1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19564342
11786533
|
NFATC2
|
CD3E
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16219537
12374807
|
FOS
|
NFATC2
|
â—¼ PROXIMITY
|
|
|
2.0
|
0.8
|
intact
|
18172215
0705181105
|
PLCG1
|
PIK3R1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
6805619
9020117
|
MAPK8
|
PIK3R1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
7033842
16982329
|
PIK3R1
|
B2M
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
15536084
11907067
|
PIK3R1
|
LCK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5220762
8246987
|
PIK3R1
|
SOS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
VAV1
|
PIK3R1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16713569
11331248
|
ZAP70
|
PIK3R1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17038529
|
PTPRJ
|
PIK3R1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
18348712
|
PIK3R1
|
MAPK8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
7642542
16982329
|
PIK3R1
|
VAV1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16713569
11331248
|
CSK
|
PTPN11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
18173375
18759926
|
PLCG1
|
PTPN11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
6805619
9020117
|
LCK
|
PTPN11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
18173375
18759926
|
CSK
|
PTPN11
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
15574420
14665621
|
PTPN11
|
HRAS
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
26617336
|
CALM3
|
RAC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9813038
8918462
|
CALM1
|
RAC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9813038
8918462
|
CALM2
|
RAC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9813038
8918462
|
PLCG1
|
LCP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
6546918
15929943
|
LCP2
|
FYN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
6546918
15929943
|
GRAP2
|
LCP2
|
â—¼ PROXIMITY
|
|
|
2.0
|
0.8
|
intact
|
29997244
20178071
|
NFKBIA
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5219675
17318178
|
MAP3K1
|
NFKBIA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9689078
16681998
|
ZAP70
|
LCK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5211965
10556826
|
LCK
|
FYN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
8946678
9973466
|
TRAV8-4
|
LCK
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
TRBC1
|
LCK
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
HLA-DRA
|
LCK
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
TRAV19
|
LCK
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
TRBV7-9
|
LCK
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
TRBV12-3
|
LCK
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
TRAV29DV5
|
LCK
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
HLA-DQA1
|
LCK
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
CD3D
|
LCK
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
HLA-DQA2
|
LCK
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
CD4
|
LCK
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
TRAC
|
LCK
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
LCK
|
HLA-DPA1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
LCK
|
CD3E
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
LCK
|
CD3G
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
LCK
|
CSK
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
15489916
15489910
|
LCK
|
PTPN6
|
â—¼ PHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
8114715
7028063
|
LCK
|
PTPRC
|
â—¼ PHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
6672875
7507203
|
FYN
|
LCK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17570479
22043010
|
FYN
|
CSK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
7524477
6730342
|
PTPN6
|
CSK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
18173375
18759926
|
HLA-DPA1
|
CSK
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
15489916
15489910
|
CD4
|
CSK
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
15489916
15489910
|
TRBV12-3
|
CSK
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
15489916
15489910
|
CD3D
|
CSK
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
15489916
15489910
|
CD3E
|
CSK
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
15489916
15489910
|
TRAV19
|
CSK
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
15489916
15489910
|
HLA-DQA2
|
CSK
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
15489916
15489910
|
CD247
|
CSK
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
15489916
15489910
|
HLA-DQA1
|
CSK
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
15489916
15489910
|
HLA-DRA
|
CSK
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
15489916
15489910
|
TRAV29DV5
|
CSK
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
15489916
15489910
|
TRBV7-9
|
CSK
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
15489916
15489910
|
TRAC
|
CSK
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
15489916
15489910
|
CD3G
|
CSK
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
15489916
15489910
|
TRAV8-4
|
CSK
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
15489916
15489910
|
TRBC1
|
CSK
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
15489916
15489910
|
CSK
|
PTPRC
|
â—¼ PHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
6672875
7507203
|
VAV1
|
CD247
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
8986718
16546099
|
CD247
|
PIK3CA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12869549
15536084
|
CD3G
|
CD247
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
HLA-DPA1
|
CD247
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
CD3E
|
CD247
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
TRBC1
|
CD247
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
HLA-DQA2
|
CD247
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
HLA-DRA
|
CD247
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
TRAV8-4
|
CD247
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
CD3D
|
CD247
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
HLA-DQA1
|
CD247
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
TRAV19
|
CD247
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
TRAC
|
CD247
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
TRBV7-9
|
CD247
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
TRAV29DV5
|
CD247
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
TRBV12-3
|
CD247
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
CD247
|
PRKCQ
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
16978534
12473184
|
CD247
|
PTPN22
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
22426112
16461343
|
PTPRC
|
CD247
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
7526385
|
LAT
|
PTPRJ
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
11259588
6673177
|
SOS1
|
PLCG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
GRAP2
|
PLCG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
11390650
11048639
|
CD3G
|
VAV1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
8986718
16546099
|
HRAS
|
VAV1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
1569084
1377053
|
VAV1
|
RAC1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
9799234
8990121
|
PIK3CA
|
VAV1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11094073
9891995
|
NFKB1
|
PTPN6
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18948549
|
SOS1
|
FYN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
FYN
|
PIK3CA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12670391
8621607
|
RAF1
|
RELA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
30761125
27554335
|
UBC
|
JUN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
7104155
19343052
|
JUN
|
MAPK8
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
18793328
10871633
|
RELA
|
JUN
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17310108
10646503
|
JUN
|
MAP2K1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9733728
20353950
|
PPP3CB
|
NFATC3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12594826
|
FOS
|
RELA
|
â—¼ PROXIMITY
|
|
|
2.0
|
0.8
|
intact
|
18172215
0705181105
|
RELA
|
FOS
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16189514
10488148
|
MAP3K1
|
MAP2K4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
6548305
9808624
|
MAP3K1
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5218828
16845370
|
MAP2K4
|
MAP3K1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
7855889
7997270
|
MAP2K4
|
MAP3K1
|
â—¼ PHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
6548305
9808624
|
RAC1
|
PRKCA
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
5218533
16628218
|
PIK3CG
|
RAC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15009099
23331499
|
PIK3CA
|
RAC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9148763
10592173
|
RAC1
|
PIK3CA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9148763
10592173
|
HLA-DPA1
|
ZAP70
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
HLA-DQA1
|
ZAP70
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
TRBV7-9
|
ZAP70
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
TRBV12-3
|
ZAP70
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
TRAV19
|
ZAP70
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
HLA-DQA2
|
ZAP70
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
TRBC1
|
ZAP70
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
TRAC
|
ZAP70
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
TRAV29DV5
|
ZAP70
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
TRAV8-4
|
ZAP70
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
HLA-DRA
|
ZAP70
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
TRAC
|
ZAP70
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
TRAV8-4
|
ZAP70
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
HLA-DPA1
|
ZAP70
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
CD3E
|
ZAP70
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
HLA-DQA2
|
ZAP70
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
HLA-DQA1
|
ZAP70
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
TRBV12-3
|
ZAP70
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
CD3D
|
ZAP70
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
CD3G
|
ZAP70
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
TRBV7-9
|
ZAP70
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
TRAV29DV5
|
ZAP70
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
TRBC1
|
ZAP70
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
HLA-DRA
|
ZAP70
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
TRAV19
|
ZAP70
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
PIK3CA
|
B2M
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
15536084
11907067
|
CD1B
|
B2M
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
12118248
5215540
|
TRAV19
|
CD4
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
CD4
|
TRBV7-9
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
CD4
|
HLA-DRA
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
CD4
|
TRAV8-4
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
CD4
|
TRBC1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
CD4
|
TRAC
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
CD4
|
CD3G
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
CD4
|
HLA-DQA2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
CD4
|
HLA-DQA1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
CD4
|
TRAV29DV5
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
CD4
|
TRBV12-3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
CD4
|
CD3D
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
CD4
|
CD3E
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
CD4
|
HLA-DPA1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
CD4
|
PTPN22
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
22426112
16461343
|
HLA-DPA1
|
CD4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12899833
16189514
|
HLA-DRA
|
PRKCQ
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
16978534
12473184
|
TRBV12-3
|
PRKCQ
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
16978534
12473184
|
TRAV8-4
|
PRKCQ
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
16978534
12473184
|
HLA-DQA2
|
PRKCQ
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
16978534
12473184
|
TRAV19
|
PRKCQ
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
16978534
12473184
|
HLA-DPA1
|
PRKCQ
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
16978534
12473184
|
HLA-DQA1
|
PRKCQ
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
16978534
12473184
|
TRAV29DV5
|
PRKCQ
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
16978534
12473184
|
CD3E
|
PRKCQ
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
16978534
12473184
|
TRAC
|
PRKCQ
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
16978534
12473184
|
CD3G
|
PRKCQ
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
16978534
12473184
|
TRBC1
|
PRKCQ
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
16978534
12473184
|
CD3D
|
PRKCQ
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
16978534
12473184
|
TRBV7-9
|
PRKCQ
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
16978534
12473184
|
PIK3CA
|
FOS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
FOS
|
NFATC1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15073183
23619911
|
FOS
|
NFKB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
20188076
|
MAP2K1
|
ELK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10716983
10997882
|
TRAC
|
HLA-DRA
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
TRAV8-4
|
HLA-DRA
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
TRBC1
|
HLA-DRA
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
TRAV19
|
HLA-DRA
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
TRBV12-3
|
HLA-DRA
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
HLA-DRA
|
CD3G
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
HLA-DRA
|
HLA-DQA2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
HLA-DRA
|
HLA-DPA1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
HLA-DRA
|
CD3D
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
HLA-DRA
|
TRBV7-9
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
HLA-DRA
|
TRAV29DV5
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
HLA-DRA
|
CD3E
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
HLA-DRA
|
HLA-DQA1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
HLA-DRA
|
PTPN22
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
22426112
16461343
|
CD3G
|
PIK3CA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12869549
15536084
|
PRKCB
|
MAPK8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12917261
9891069
|
TRBC1
|
CD3D
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
TRBV12-3
|
CD3D
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
HLA-DQA1
|
CD3D
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
TRAV19
|
CD3D
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
TRAV8-4
|
CD3D
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
HLA-DQA2
|
CD3D
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
TRAC
|
CD3D
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
CD3D
|
TRBV7-9
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
CD3D
|
CD3G
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
CD3D
|
CD3E
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
CD3D
|
HLA-DPA1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
CD3D
|
TRAV29DV5
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
CD3D
|
PTPN22
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
22426112
16461343
|
TRBC1
|
CD3E
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
HLA-DQA1
|
CD3E
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
TRAV8-4
|
CD3E
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
HLA-DQA2
|
CD3E
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
TRBV12-3
|
CD3E
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
TRAV19
|
CD3E
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
TRAC
|
CD3E
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
TRBV7-9
|
CD3E
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
TRAV29DV5
|
CD3E
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
CD3E
|
CD3G
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
CD3E
|
HLA-DPA1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
CD3E
|
PTPN22
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
22426112
16461343
|
PPP3CC
|
NFATC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11062529
18676376
|
TRAV8-4
|
HLA-DQA1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
TRBV12-3
|
HLA-DQA1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
HLA-DQA2
|
HLA-DQA1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
TRAC
|
HLA-DQA1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
TRBC1
|
HLA-DQA1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
TRAV19
|
HLA-DQA1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
HLA-DQA1
|
TRBV7-9
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
HLA-DQA1
|
TRAV29DV5
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
HLA-DQA1
|
CD3G
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
HLA-DQA1
|
HLA-DPA1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
HLA-DQA1
|
PTPN22
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
22426112
16461343
|
TRAV8-4
|
HLA-DQA2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
TRBV12-3
|
HLA-DQA2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
TRBC1
|
HLA-DQA2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
TRAC
|
HLA-DQA2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
TRAV19
|
HLA-DQA2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
HLA-DQA2
|
HLA-DPA1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
HLA-DQA2
|
TRAV29DV5
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
HLA-DQA2
|
TRBV7-9
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
HLA-DQA2
|
CD3G
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
HLA-DQA2
|
PTPN22
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
22426112
16461343
|
TRAC
|
HLA-DPA1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
TRAV29DV5
|
HLA-DPA1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
TRAV19
|
HLA-DPA1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
TRBV12-3
|
HLA-DPA1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
CD3G
|
HLA-DPA1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
TRAV8-4
|
HLA-DPA1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
TRBV7-9
|
HLA-DPA1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
TRBC1
|
HLA-DPA1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
HLA-DPA1
|
PTPN22
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
22426112
16461343
|
TRBC1
|
CD3G
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
TRBV7-9
|
CD3G
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
TRAV29DV5
|
CD3G
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
TRAV19
|
CD3G
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
TRAC
|
CD3G
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
TRAV8-4
|
CD3G
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
TRBV12-3
|
CD3G
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
CD3G
|
PTPN22
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
22426112
16461343
|
TRBV7-9
|
PTPN22
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
22426112
16461343
|
TRAV8-4
|
PTPN22
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
22426112
16461343
|
TRAV19
|
PTPN22
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
22426112
16461343
|
TRBC1
|
PTPN22
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
22426112
16461343
|
TRBV12-3
|
PTPN22
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
22426112
16461343
|
TRAC
|
PTPN22
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
22426112
16461343
|
TRAV29DV5
|
PTPN22
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
22426112
16461343
|
TRAC
|
TRBC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5215899
12429093
|
TRBV12-3
|
TRAC
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
TRAV8-4
|
TRAC
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
TRAV19
|
TRAC
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
TRAC
|
TRBV7-9
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
TRAC
|
TRAV29DV5
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
TRAC
|
TRBC1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
TRAV19
|
TRBV12-3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
TRBV12-3
|
TRBV7-9
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
TRBV12-3
|
TRAV8-4
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
TRBV12-3
|
TRAV29DV5
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
TRBV12-3
|
TRBC1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
TRAV19
|
TRBV7-9
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
TRBC1
|
TRBV7-9
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
TRAV8-4
|
TRBV7-9
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
TRBV7-9
|
TRAV29DV5
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
TRAV8-4
|
TRAV29DV5
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
TRBC1
|
TRAV29DV5
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
TRAV19
|
TRAV29DV5
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
TRAV8-4
|
TRBC1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
TRAV19
|
TRAV8-4
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
TRAV19
|
TRBC1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
MAPK3
|
PTPN7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
804.0
|
0.8
|
STRING
|
36370105
|
LCK
|
CD3E
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.81
|
0.81
|
HIPPIE
|
14523017
11855827
|
UBC
|
ZAP70
|
â—¼ PHYSICAL_INTERACTION
|
|
|
813.0
|
0.81
|
STRING
|
36370105
|
RAC1
|
GRB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
31980649
|
GRB2
|
CSK
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
31980649
21706016
|
GRB2
|
ZAP70
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
23267066
7629168
|
RAF1
|
LCK
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
16189514
8939988
|
CSK
|
JUN
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
19818398
16740711
|
CD247
|
CD3D
|
â—¼ PHYSICAL_INTERACTION
|
|
|
835.0
|
0.83
|
STRING
|
36370105
|
CD3D
|
CD3G
|
â—¼ PHYSICAL_INTERACTION
|
|
|
835.0
|
0.83
|
STRING
|
36370105
|
LCK
|
PTPN6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
838.0
|
0.83
|
STRING
|
36370105
|
LAT
|
LCP2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
24584089
16189514
9489702
23514740
|
CSK
|
LCK
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
15144186
31980649
12485116
|
ZAP70
|
FYN
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
7760813
16189514
16713569
|
CD8A
|
LCK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
848.0
|
0.84
|
STRING
|
36370105
|
LCK
|
LCP2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
16354835
8702662
10556826
21725281
|
PTPRC
|
LCK
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.85
|
0.85
|
mint
|
7507203
6672875
|
PTPRC
|
LCK
|
â—¼ PHOSPHORYLATION
|
✅
|
|
0.85
|
0.85
|
mint
|
7507203
6672875
|
PTPRC
|
LCK
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
0.85
|
0.85
|
mint
|
10369126
8310409
|
LCK
|
PTPRC
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
0.85
|
0.85
|
mint
|
7507203
6672875
|
LAT
|
ZAP70
|
â—¼ PHYSICAL_INTERACTION
|
|
|
849.0
|
0.85
|
STRING
|
36370105
|
MAPK8
|
JUN
|
â—¼ PHOSPHORYLATION
|
✅
|
|
0.85
|
0.85
|
mint
|
7148309
19527717
|
PPP3CA
|
NFATC1
|
â—¼ DEPHOSPHORYLATION
|
✅
|
+
|
0.85
|
0.85
|
Signor
|
14722106
|
CD8A
|
CD8B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
851.0
|
0.85
|
STRING
|
36370105
|
MAPK8
|
NFATC3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
852.0
|
0.85
|
STRING
|
36370105
|
MAPK8
|
NFATC3
|
â—¼ PHOSPHORYLATION
|
✅
|
-
|
0.85
|
0.85
|
Signor
|
14517246
|
PIK3R1
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.86
|
0.86
|
mint
|
5220480
7642581
|
ZAP70
|
LCP2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
10660534
8702662
24584089
9047237
12190313
|
CSK
|
PTPRC
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
7507203
19167335
|
ELK1
|
MAPK8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
859.0
|
0.86
|
STRING
|
36370105
|
CALM3
|
PPP3CA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
867.0
|
0.86
|
STRING
|
36370105
|
CALM1
|
PPP3CA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
867.0
|
0.86
|
STRING
|
36370105
|
CALM2
|
PPP3CA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
867.0
|
0.86
|
STRING
|
36370105
|
RAC1
|
VAV1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
867.0
|
0.86
|
STRING
|
36370105
|
CSK
|
FYN
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
16713569
8262983
7524477
1985196
|
ZAP70
|
LAT
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
16906159
12186560
11368773
23514740
|
ZAP70
|
PLCG1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
16467851
7629168
8906806
|
VAV1
|
ZAP70
|
â—¼ PHYSICAL_INTERACTION
|
|
|
869.0
|
0.87
|
STRING
|
36370105
|
LCP2
|
ZAP70
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
HRAS
|
PIK3CA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
871.0
|
0.87
|
STRING
|
36370105
|
B2M
|
CD1C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
873.0
|
0.87
|
STRING
|
36370105
|
LCP2
|
VAV1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
874.0
|
0.87
|
STRING
|
36370105
|
CD247
|
LCK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
877.0
|
0.87
|
STRING
|
36370105
|
PPP3CB
|
PPP3CC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
877.0
|
0.87
|
STRING
|
36370105
|
LCP2
|
PLCG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
881.0
|
0.88
|
STRING
|
36370105
|
LCK
|
PTPRC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
881.0
|
0.88
|
STRING
|
36370105
|
LAT
|
PLCG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
881.0
|
0.88
|
STRING
|
36370105
|
CD3E
|
ZAP70
|
â—¼ PHYSICAL_INTERACTION
|
|
|
881.0
|
0.88
|
STRING
|
36370105
|
ELK1
|
MAPK3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
882.0
|
0.88
|
STRING
|
36370105
|
LCK
|
ZAP70
|
â—¼ PHYSICAL_INTERACTION
|
|
|
882.0
|
0.88
|
STRING
|
36370105
|
MAP3K1
|
MAPK8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
885.0
|
0.88
|
STRING
|
36370105
|
CD3D
|
CD3E
|
â—¼ PHYSICAL_INTERACTION
|
|
|
887.0
|
0.88
|
STRING
|
36370105
|
GRB2
|
LCP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
889.0
|
0.89
|
STRING
|
36370105
|
GRAP2
|
LAT
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
16189514
10021361
10224278
|
RAF1
|
FYN
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
16713569
16189514
7517401
|
MAP2K4
|
MAP3K1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
889.0
|
0.89
|
STRING
|
36370105
|
FOS
|
NFATC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
890.0
|
0.89
|
STRING
|
36370105
|
PTPN11
|
SOS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
891.0
|
0.89
|
STRING
|
36370105
|
GRB2
|
VAV1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
894.0
|
0.89
|
STRING
|
36370105
|
LAT
|
GRB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
7544353
16906159
12186560
16189514
9489702
16713569
8063801
16938345
10811803
12359715
23460737
11368773
|
FYN
|
GRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
7499280
9344857
|
MAPK3
|
RAC1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
17202194
15657136
21419341
|
MAPK3
|
MAP2K1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
10567369
19219045
8013650
|
MAPK3
|
PTPN6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
16231973
12459785
23109003
|
MAPK3
|
PTPN11
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
8197172
|
PPP3CA
|
NFATC4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10860980
16407284
21880741
|
PIK3R1
|
PIK3CG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
8596638
14665640
11733063
|
PTPN11
|
PIK3CA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10386953
7522233
|
SOS1
|
LCP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
11390650
10021361
10224278
|
LCK
|
PTPRC
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
9533446
24463463
19167335
15085197
8576115
8473339
7507203
14625311
10369126
|
LCK
|
LAT
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
16938345
12186560
12359715
14523017
|
LCK
|
ZAP70
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
16189514
7961936
10556826
8798643
9685404
22242145
7539035
10318843
15144186
16461343
|
LCK
|
PLCG1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
7682059
17570479
1500851
|
LCK
|
RAF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
7935389
8939988
16189514
|
PLCG1
|
CD247
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
7517665
8657103
15161916
|
FYN
|
LAT
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16938345
|
MAPK8
|
LAT
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
15192708
|
CD3G
|
PLCG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
7517665
8657103
15161916
|
CD3E
|
ZAP70
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
8906806
11855827
8366117
8647168
7761456
|
CD8A
|
B2M
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
15136729
15534202
16551255
|
CD8B
|
B2M
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
15136729
15534202
16551255
|
NFKB1
|
B2M
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12480693
2196446
|
PRKCQ
|
RASGRP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
15899849
9819387
|
HLA-DRA
|
HLA-DPA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
9312039
1956401
16618111
|
HLA-DRA
|
HLA-DQA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
9312039
1956401
16618111
|
HLA-DRA
|
HLA-DQA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
9312039
1956401
16618111
|
PIK3CA
|
SOS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
21653832
16456001
10068651
|
MAPK8
|
MAP2K4
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
16186825
9162092
17875933
|
GRAP2
|
SOS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
11390650
10021361
10224278
|
MAPK8
|
NFATC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
16648474
10978313
11274345
|
HLA-DQA2
|
HLA-DQA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
9312039
1956401
16618111
|
HLA-DQA1
|
HLA-DPA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
9312039
1956401
16618111
|
HLA-DQA2
|
HLA-DPA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
9312039
1956401
16618111
|
SOS1
|
HRAS
|
â—¼ GTPASE_REACTION
|
✅
|
+
|
0.9
|
0.9
|
Signor
|
23132018
|
GRB2
|
SOS1
|
â—¼ RELOCALIZATION
|
✅
|
+
|
0.9
|
0.9
|
Signor
|
23452850
|
GRB2
|
PIK3R1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
908.0
|
0.9
|
STRING
|
36370105
|
PIK3R1
|
PTPN11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
912.0
|
0.91
|
STRING
|
36370105
|
LCP2
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.92
|
0.92
|
mint
|
17235283
5219525
|
ZAP70
|
CD247
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.92
|
0.92
|
mint
|
7528772
6730352
|
GRAP2
|
LCP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
923.0
|
0.92
|
STRING
|
36370105
|
CD247
|
CD3E
|
â—¼ PHYSICAL_INTERACTION
|
|
|
923.0
|
0.92
|
STRING
|
36370105
|
MAP2K4
|
MAPK8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
926.0
|
0.92
|
STRING
|
36370105
|
JUN
|
NFATC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
931.0
|
0.93
|
STRING
|
36370105
|
CD3E
|
CD3G
|
â—¼ PHYSICAL_INTERACTION
|
|
|
932.0
|
0.93
|
STRING
|
36370105
|
NFATC1
|
PPP3CA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
935.0
|
0.93
|
STRING
|
36370105
|
B2M
|
CD8A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
936.0
|
0.93
|
STRING
|
36370105
|
SOS1
|
HRAS
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.94
|
0.94
|
mint
|
17084389
5219305
|
CD3G
|
CD3E
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.94
|
0.94
|
HIPPIE
|
20890284
9582308
2138083
|
HRAS
|
PIK3CG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
943.0
|
0.94
|
STRING
|
36370105
|
GRB2
|
PTPN11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
949.0
|
0.95
|
STRING
|
36370105
|
SOS1
|
FYN
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.95
|
0.95
|
HIPPIE
|
17474147
16713569
9856337
|
PLCG1
|
GRB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
16713569
7629168
7516467
9020117
21706016
10940929
16038803
9281317
|
CD4
|
LCK
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
17653867
16888650
16189514
15047060
11854499
12007789
8104794
8246987
17005671
|
SOS1
|
PLCG1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
16713569
17474147
9020117
10940929
10913276
|
RAF1
|
MAP2K1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.96
|
0.96
|
mint
|
7014125
19197339
|
MAP2K1
|
MAPK3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
963.0
|
0.96
|
STRING
|
36370105
|
B2M
|
CD1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
968.0
|
0.96
|
STRING
|
36370105
|
SOS1
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.97
|
0.97
|
mint
|
5220480
7642581
|
LCP2
|
GRB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
8695800
11314042
10204582
8995445
15929943
12176364
25416956
32296183
9565634
10224278
7706237
20936779
19380743
17235283
9716598
|
PIK3R1
|
PIK3CA
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.97
|
0.97
|
mint
|
20018188
7383613
|
GRAP2
|
LCP2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
16189514
15929943
25416956
21516116
17235283
32296183
17010654
31467278
10021361
20534575
10820259
12176364
12496419
26264872
10224278
27107012
29997244
32814053
12773374
|
LCP2
|
PLCG1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
11390650
15929943
21725281
16467851
7706237
|
LAT
|
PLCG1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
7544353
9489702
16713569
16467851
16938345
10811803
27221712
24642916
9729044
11368773
|
MAP2K1
|
RAF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
971.0
|
0.97
|
STRING
|
36370105
|
CD4
|
LCK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
976.0
|
0.97
|
STRING
|
36370105
|
LCP2
|
GRAP2
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.98
|
0.98
|
mint
|
17235283
5219525
|
HRAS
|
RAF1
|
â—¼ PROXIMITY
|
✅
|
|
0.98
|
0.98
|
mint
|
18273062
6540139
|
RAF1
|
HRAS
|
â—¼ PROXIMITY
|
✅
|
|
0.98
|
0.98
|
mint
|
18273062
6540139
|
B2M
|
CD1D
|
â—¼ PHYSICAL_INTERACTION
|
|
|
979.0
|
0.98
|
STRING
|
36370105
|
B2M
|
CD1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
983.0
|
0.98
|
STRING
|
36370105
|
FOS
|
JUN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
985.0
|
0.98
|
STRING
|
36370105
|
NFKB1
|
NFKBIA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
987.0
|
0.98
|
STRING
|
36370105
|
HRAS
|
SOS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
989.0
|
0.99
|
STRING
|
36370105
|
GRB2
|
SOS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
NFKBIA
|
RELA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
JUN
|
MAPK8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
GRB2
|
MAP3K1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
41.0
|
1.0
|
ACSN
|
10086337
10465784
10567412
10811803
10982827
11274345
11447289
11668179
11777939
12040186
12048245
12175651
12419216
12640133
12738796
12782630
14585353
15170913
15567848
15574420
15863030
16102570
16227978
16488589
16582911
16887996
17496910
17496911
17673906
18855897
19449109
19568798
19615955
21102635
21614932
24027568
26552706
7510700
8551221
9379049
9582321
|
GRB2
|
RAC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
32.0
|
1.0
|
ACSN
|
10086337
10567412
10811803
10982827
11274345
11447289
11756498
11777939
12040186
12175651
12640133
12738796
14585353
15567848
15574420
15863030
16102570
16582911
16887996
17496910
17673906
18000759
18855897
19151919
19449109
19568798
21614932
24027568
26552706
27331412
7510700
8551221
|
GRB2
|
LAT
|
â—¼ PHYSICAL_INTERACTION
|
|
|
51.0
|
1.0
|
ACSN
|
10072481
10086337
10209041
10567412
10781611
10811803
10925299
10982827
11169415
11447289
11532940
11777939
11994416
12175651
12640133
1281218
12845332
14764585
15214048
15567848
15574420
16102570
16329184
16582911
16887996
1712101
17397400
17496910
17673906
19449109
19494291
19909365
23523669
23620508
24584707
25137453
2536067
25456276
25960930
26552706
7523143
7682895
7890616
8226994
8551221
8649391
8976179
8995379
9489702
9535722
9846483
|
GRB2
|
RAF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
54.0
|
1.0
|
ACSN
|
10086337
10567412
10811803
10843677
10982827
11034387
11062502
11385609
11447289
11532940
11777939
11907067
12040186
12175651
12419216
12479806
12566895
12640133
12782630
14585353
14764585
15169888
15516985
15536084
15547943
15567848
15574420
15735649
15863030
16102570
16227978
16488589
16582911
16887996
17178906
17395718
17496910
17673906
18039929
19289794
19449109
19541618
19565474
19568798
19615955
21102635
22435554
24027568
26552706
7510700
8551221
8929532
9069260
9510155
|
GRB2
|
PLCG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
51.0
|
1.0
|
ACSN
|
10072481
10086337
10209041
10567412
10781611
10811803
10925299
10982827
11169415
11447289
11532940
11777939
11994416
12175651
12640133
1281218
12845332
14764585
15214048
15567848
15574420
16102570
16329184
16582911
16887996
1712101
17397400
17496910
17673906
19449109
19494291
19909365
23523669
23620508
24584707
25137453
2536067
25456276
25960930
26552706
7523143
7682895
7890616
8226994
8551221
8649391
8976179
8995379
9489702
9535722
9846483
|
SOS1
|
GRB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
1.0
|
1.0
|
HIPPIE
|
28514442
16520382
31980649
32062451
8493579
21988832
14679214
7510700
7514169
21706016
10319320
32203420
9872323
9797459
34407391
16906159
10716926
12577067
8810325
7629168
11960376
7664271
8626525
15192046
7629138
11997436
8943292
10207103
8695800
10570290
10025673
8112292
11726515
8816480
20473329
7559490
7773779
9447984
19380743
7642581
7527391
9716598
9344843
10477741
16713569
19323566
7516467
17474147
9569023
8188688
16893902
11964172
9478994
33961781
8479541
28166272
9009162
|
GRB2
|
LAT
|
â—¼ PROTEIN_INTERACTION
|
|
|
51.0
|
1.0
|
ACSN
|
10072481
10086337
10209041
10567412
10781611
10811803
10925299
10982827
11169415
11447289
11532940
11777939
11994416
12175651
12640133
1281218
12845332
14764585
15214048
15567848
15574420
16102570
16329184
16582911
16887996
1712101
17397400
17496910
17673906
19449109
19494291
19909365
23523669
23620508
24584707
25137453
2536067
25456276
25960930
26552706
7523143
7682895
7890616
8226994
8551221
8649391
8976179
8995379
9489702
9535722
9846483
|
GRB2
|
RAC1
|
â—¼ SHARES_COMPLEX
|
|
|
32.0
|
1.0
|
ACSN
|
10086337
10567412
10811803
10982827
11274345
11447289
11756498
11777939
12040186
12175651
12640133
12738796
14585353
15567848
15574420
15863030
16102570
16582911
16887996
17496910
17673906
18000759
18855897
19151919
19449109
19568798
21614932
24027568
26552706
27331412
7510700
8551221
|
GRB2
|
PLCG1
|
â—¼ SHARES_COMPLEX
|
|
|
51.0
|
1.0
|
ACSN
|
10072481
10086337
10209041
10567412
10781611
10811803
10925299
10982827
11169415
11447289
11532940
11777939
11994416
12175651
12640133
1281218
12845332
14764585
15214048
15567848
15574420
16102570
16329184
16582911
16887996
1712101
17397400
17496910
17673906
19449109
19494291
19909365
23523669
23620508
24584707
25137453
2536067
25456276
25960930
26552706
7523143
7682895
7890616
8226994
8551221
8649391
8976179
8995379
9489702
9535722
9846483
|
GRB2
|
MAP3K1
|
â—¼ SHARES_COMPLEX
|
|
|
41.0
|
1.0
|
ACSN
|
10086337
10465784
10567412
10811803
10982827
11274345
11447289
11668179
11777939
12040186
12048245
12175651
12419216
12640133
12738796
12782630
14585353
15170913
15567848
15574420
15863030
16102570
16227978
16488589
16582911
16887996
17496910
17496911
17673906
18855897
19449109
19568798
19615955
21102635
21614932
24027568
26552706
7510700
8551221
9379049
9582321
|
GRB2
|
RAF1
|
â—¼ SHARES_COMPLEX
|
|
|
54.0
|
1.0
|
ACSN
|
10086337
10567412
10811803
10843677
10982827
11034387
11062502
11385609
11447289
11532940
11777939
11907067
12040186
12175651
12419216
12479806
12566895
12640133
12782630
14585353
14764585
15169888
15516985
15536084
15547943
15567848
15574420
15735649
15863030
16102570
16227978
16488589
16582911
16887996
17178906
17395718
17496910
17673906
18039929
19289794
19449109
19541618
19565474
19568798
19615955
21102635
22435554
24027568
26552706
7510700
8551221
8929532
9069260
9510155
|
FYN
|
GRB2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
9822663
15886116
10849438
12670394
|
HRAS
|
GRB2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
11.0
|
1.0
|
Reactome
|
19946327
11429702
11157491
18757403
21666749
21711248
18381441
19103595
21160078
9857065
20179196
|
FOS
|
GRB2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
11.0
|
1.0
|
ACSN
|
11274345
12738796
15067049
16393692
16394015
18039929
19667062
21385848
22634314
23430059
9064320
|
LCK
|
GRB2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
16.0
|
1.0
|
ACSN
|
10652356
11062502
12731048
12740575
15536084
17544292
19290918
20814939
21127503
22513334
23620508
8478617
8986721
9438848
9738502
9751747
|
CD247
|
GRB2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
24.0
|
1.0
|
ACSN
|
10562324
10925299
11353765
11438547
11875494
12415267
12731048
12811837
15735648
16713974
17371980
20435894
20814939
21059766
23414611
23508573
23620508
23886063
24378531
7600293
8478617
8642247
9625766
9738502
|
JUN
|
GRB2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
ACSN
|
11274345
12738796
17439715
18039929
26587781
8545107
|
ZAP70
|
GRB2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
24.0
|
1.0
|
ACSN
|
10562324
10925299
11353765
11438547
11875494
12415267
12731048
12811837
15735648
16713974
17371980
20435894
20814939
21059766
23414611
23508573
23620508
23886063
24378531
7600293
8478617
8642247
9625766
9738502
|
PTPN11
|
GRB2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
10.0
|
1.0
|
ACSN
|
10358138
11447289
11572860
12138178
12707331
15240681
15699106
15713798
19833085
9751747
|
GRB2
|
VAV1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
57.0
|
1.0
|
ACSN
|
10077632
10086337
10426994
10567412
10646608
10679059
10714681
10811803
10849438
10898494
10982827
11080163
11447289
11526404
11698448
11754814
11777939
11777960
11907067
11994416
12094222
12165654
12175651
12186560
12616499
12626562
12640133
12740575
12885870
12917349
14764585
15169881
15536084
15567848
15574420
16339513
16582911
16713974
16887996
17070508
17100878
17496910
17673906
18490724
19449109
19909365
20189481
22513334
22786724
22952938
25355530
25539813
26552706
8189062
8226994
8551221
9438848
|
GRB2
|
PIK3R1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
32.0
|
1.0
|
ACSN
|
10086337
10567412
10811803
10849428
10982827
11335727
11447289
11449354
11532940
11777939
12175651
12393695
12640133
15308668
15567848
15574420
16000375
16076871
16530705
16582911
16887996
17496910
17673906
18835194
19449109
19454690
22064427
22464172
24217602
25922287
26552706
8551221
|
GRB2
|
PLCG1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
51.0
|
1.0
|
ACSN
|
10072481
10086337
10209041
10567412
10781611
10811803
10925299
10982827
11169415
11447289
11532940
11777939
11994416
12175651
12640133
1281218
12845332
14764585
15214048
15567848
15574420
16102570
16329184
16582911
16887996
1712101
17397400
17496910
17673906
19449109
19494291
19909365
23523669
23620508
24584707
25137453
2536067
25456276
25960930
26552706
7523143
7682895
7890616
8226994
8551221
8649391
8976179
8995379
9489702
9535722
9846483
|
GRB2
|
LAT
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
51.0
|
1.0
|
ACSN
|
10072481
10086337
10209041
10567412
10781611
10811803
10925299
10982827
11169415
11447289
11532940
11777939
11994416
12175651
12640133
1281218
12845332
14764585
15214048
15567848
15574420
16102570
16329184
16582911
16887996
1712101
17397400
17496910
17673906
19449109
19494291
19909365
23523669
23620508
24584707
25137453
2536067
25456276
25960930
26552706
7523143
7682895
7890616
8226994
8551221
8649391
8976179
8995379
9489702
9535722
9846483
|
GRB2
|
MAP2K4
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
32.0
|
1.0
|
ACSN
|
10086337
10567412
10811803
10982827
11274345
11447289
11756498
11777939
12040186
12175651
12640133
12738796
14585353
15567848
15574420
15863030
16102570
16582911
16887996
17496910
17673906
18000759
18855897
19151919
19449109
19568798
21614932
24027568
26552706
27331412
7510700
8551221
|
GRB2
|
LCP2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
26.0
|
1.0
|
ACSN
|
10086337
10426994
10567412
10811803
10982827
11447289
11777939
11777960
11907067
12175651
12640133
15536084
15567848
15574420
16339513
16582911
16713974
16887996
17070508
17100878
17496910
17673906
18490724
19449109
26552706
8551221
|
GRB2
|
FYN
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
52.0
|
1.0
|
ACSN
|
10022831
10086337
10567412
10811803
10849428
10982827
11166270
11447289
11449354
11532940
11777939
11960372
12175651
12393695
12629515
12640133
13678960
15099563
15111329
15501236
15520864
15567848
15573129
15574420
16002046
16076871
16572188
16582911
16887996
17086423
17496910
17673906
17883421
19414323
19449109
21372296
21378271
22064427
22461508
23390297
23896411
24217602
24346288
24670066
25922287
26201938
26552706
8551221
8837607
9157999
9570538
9753319
|
LAT
|
GRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
27.0
|
1.0
|
Omnipath
|
11368773
9489702
10811803
8063801
17043143
16938345
16713569
23150273
12186560
16906159
|
LCP2
|
GRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
20.0
|
1.0
|
Omnipath
|
7706237
20936779
10224278
8695800
17235283
15929943
25416956
19380743
9716598
32296183
10204582
11314042
8995445
|
PTPN11
|
GRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
66.0
|
1.0
|
Omnipath
|
8702859
9361008
16371368
21706016
8041791
11085989
8978300
11432792
15882975
9362449
10212213
11684012
7523381
10592173
16189514
10747947
10973965
9632781
8959326
11602579
12577067
9254654
10080542
15010462
31585087
12531430
8995399
19380743
7522233
9804835
7534299
9824671
9660791
|
VAV1
|
GRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
32.0
|
1.0
|
Omnipath
|
8900182
10207103
9013873
15558030
7651724
7809090
8621483
29997244
18692475
7478592
16713569
11406576
9209406
16339550
|
GRB2
|
SOS1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
145.0
|
1.0
|
Omnipath
|
9544989
9872323
7642581
15746962
11726515
8621483
23334917
16520382
11997436
21706016
10359574
8950973
7664271
16713569
16893902
16906159
21988832
19323566
9009162
10716926
11964172
7629168
9815779
10592173
9716598
8647802
28166272
7773778
7773779
18778683
8188688
10319320
8810325
9344843
23452850
11960376
8816480
10025673
7510700
8940013
12955078
9697839
12345678
10477741
8493579
8943292
12577067
7862167
9199344
8112292
7898932
10207103
8695800
19531499
10570290
7760801
20005866
19380743
9447984
8235613
8479540
7527391
14679214
8479541
17474147
7514169
7629138
|
GRB2
|
PLCG1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
9281317
15953601
7629168
9020117
16713569
10940929
|
GRB2
|
HRAS
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
17496910
16713569
17673906
11352655
|
HRAS
|
MAPK3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
Reactome
|
15035987
21779496
24957944
22510884
23352452
25907612
|
RAF1
|
MAPK3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
25435214
20179705
20141835
16364920
20130576
15035987
25907612
|
ELK1
|
MAPK3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
8386592
11145955
7588619
7889942
|
MAP3K1
|
MAPK3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
23331499
25241761
15315965
12049732
24135036
|
PTPRJ
|
MAPK3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
12771128
19167335
19494114
|
PRKCA
|
MAPK3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
11704645
12598525
19074803
8903320
9160888
|
MAP2K1
|
MAPK3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
106.0
|
1.0
|
Omnipath
|
9694850
17081983
11319218
18799465
17389395
9447970
15342917
8226933
15851026
12270934
12644307
11242034
1381507
17906627
9677429
11986622
8376945
7992057
11948414
7687743
9731057
19197339
11704645
7565670
12750173
12932319
8626767
23331499
12048245
7559390
17272394
15811950
26987942
19494114
18669648
18691976
17192257
8388392
7898932
16464493
19369195
12920017
15466214
19690332
11134045
19534553
10995751
7867743
8223433
8248196
10567369
19933846
17563371
1518847
11730323
18983981
16186792
16135787
15951569
19058874
15212693
10748187
9560161
9925641
9733512
18083107
11104681
9006895
17569879
21071413
7731720
1330321
93330262
19541618
15466476
12925710
11971971
11136732
11118451
10746662
|
MAPK3
|
FOS
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
41.0
|
1.0
|
Omnipath
|
17018293
12134156
20506250
15547943
7816602
15084594
12697810
8226933
12738796
16393692
17255949
17439715
15187187
19541618
23109003
19565474
17722974
17052211
7588633
8545107
16055710
8388392
18039929
12972619
18775330
26725323
21098038
9604935
11274345
|
MAPK3
|
LAT
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
15192708
|
MAPK3
|
NFATC4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
15657420
|
MAPK3
|
ELK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
64.0
|
1.0
|
Omnipath
|
17145710
9130707
20506250
15547943
20371703
7618106
7601337
12697810
12473660
23331499
8007980
16291755
16393692
16998585
18988627
17255949
8208531
15014501
15187187
8586671
19541618
11145955
25241761
19565474
11309409
8887554
17052211
15277685
18334532
15782123
8548291
14499342
9927426
7889942
8262053
8386592
10716983
12665513
15967991
8477450
12947314
15212693
11274345
|
MAPK3
|
LCK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
8506364
8618896
8226850
7597029
|
MAPK3
|
PTPN7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
10559944
10206983
10415025
18088087
16226275
|
MAPK3
|
NFATC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
10652349
|
MAPK3
|
SOS1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
29145629
7478566
23331499
8816480
7739560
17570479
9922370
|
MAPK3
|
RAF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
14654779
23331499
19541618
18691976
16407412
19933846
9446616
9922370
15664191
18988627
|
CALM1
|
NFATC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
8576111
8631904
10860980
9727000
8799126
|
PPP3CB
|
NFATC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
8576111
8631904
10860980
9727000
8799126
|
PPP3CA
|
NFATC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
8576111
8631904
10860980
9727000
8799126
|
NFATC2
|
CD4
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
21799768
10692237
17463169
16880206
16219537
9916709
10799559
|
NFATC1
|
NFATC2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
19915002
18078995
15657420
18299389
16455648
11402342
11030334
|
MAPK8
|
NFATC2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
15743762
14517246
16648474
10978313
17570479
11274345
|
PPP3CA
|
NFATC2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
10860980
9660947
24954618
11062529
21880741
12594826
16407284
18676376
11030334
|
PPP3CB
|
NFATC2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
9660947
11062529
12594826
18676376
8631904
11030334
|
PPP3CC
|
NFATC2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
9660947
11062529
18676376
11030334
|
MAPK8
|
NFATC4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
16648474
10978313
17875713
27893713
11274345
|
PIK3CA
|
PIK3R1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
1.0
|
STRING
|
36370105
|
HRAS
|
PIK3R1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
9069260
25241761
10212255
11313862
9150145
16713569
15021914
|
LAT
|
PIK3R1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
11368773
9489702
19132916
23109003
16713569
14696041
|
PTPN11
|
PIK3R1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
15.0
|
1.0
|
Omnipath
|
11593409
18950707
15790353
23109003
16371368
17722974
22315502
16107703
9660791
9918857
8080844
9632795
10973965
|
CD3E
|
PIK3R1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
9312149
11855827
11689561
|
LCK
|
PIK3R1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
8294442
11337495
8246987
14583609
11526404
15032589
23109003
9461588
7504174
8397196
10488096
|
FYN
|
PIK3R1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
8294442
8394019
7515100
17570479
16713569
7520528
1652056
|
PTPN6
|
PIK3R1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
11.0
|
1.0
|
Omnipath
|
21780115
11337495
11526404
15032589
9065461
11160222
23109003
22880054
10488096
|
PIK3R1
|
RAC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
7629060
8034624
12086876
12515821
|
PIK3R1
|
SOS1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
17474147
19531499
25241761
|
PTPN11
|
PTPN6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
42.0
|
1.0
|
ACSN
|
10358138
11447289
11449354
11572860
12138178
12176909
1238444
12393695
12421919
12707331
12773515
12917349
15169881
15240681
15699106
15713798
16204085
17371980
19833085
20007250
20038811
20363967
20435894
21469115
22437870
22483603
22513334
22683124
22952938
22955274
23732914
25355530
26667266
26755705
26885856
27474009
27806234
28893624
8976179
8986721
9751747
9765283
|
PTPN11
|
PTPN6
|
â—¼ SHARES_COMPLEX
|
|
|
42.0
|
1.0
|
ACSN
|
10358138
11447289
11449354
11572860
12138178
12176909
1238444
12393695
12421919
12707331
12773515
12917349
15169881
15240681
15699106
15713798
16204085
17371980
19833085
20007250
20038811
20363967
20435894
21469115
22437870
22483603
22513334
22683124
22952938
22955274
23732914
25355530
26667266
26755705
26885856
27474009
27806234
28893624
8976179
8986721
9751747
9765283
|
FYN
|
PTPN11
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
13.0
|
1.0
|
ACSN
|
10591186
10648627
12218089
12731048
19290918
19909365
20814939
21378271
22683124
22863785
24440149
27192565
9738502
|
PTPN11
|
CD247
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
15.0
|
1.0
|
ACSN
|
10358138
10849428
10982827
11447289
11572860
12138178
12640133
12707331
15240681
15699106
15713798
16212621
19833085
19909365
9751747
|
HLA-DQA1
|
PTPN11
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
12947224
15358536
18173375
18759926
|
HLA-DQA2
|
PTPN11
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
12947224
15358536
18173375
18759926
|
TRAV29DV5
|
PTPN11
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
12947224
15358536
18173375
18759926
|
TRBV12-3
|
PTPN11
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
12947224
15358536
18173375
18759926
|
CD3G
|
PTPN11
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
12947224
15358536
18173375
18759926
|
TRAV19
|
PTPN11
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
12947224
15358536
18173375
18759926
|
TRAC
|
PTPN11
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
12947224
15358536
18173375
18759926
|
LCK
|
PTPN11
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
12947224
15358536
18173375
18759926
|
CD3D
|
PTPN11
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
12947224
15358536
18173375
18759926
|
HLA-DPA1
|
PTPN11
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
12947224
15358536
18173375
18759926
|
TRAV8-4
|
PTPN11
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
12947224
15358536
18173375
18759926
|
CD247
|
PTPN11
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
12947224
15358536
18173375
18759926
|
TRBC1
|
PTPN11
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
12947224
15358536
18173375
18759926
|
TRBV7-9
|
PTPN11
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
12947224
15358536
18173375
18759926
|
HLA-DRA
|
PTPN11
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
12947224
15358536
18173375
18759926
|
CD4
|
PTPN11
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
12947224
15358536
18173375
18759926
|
CD3E
|
PTPN11
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
12947224
15358536
18173375
18759926
|
FYN
|
PTPN11
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
10212213
11157475
16713569
|
PRKCA
|
PTPN11
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
16055440
11781100
|
PTPN11
|
SOS1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
12577067
9632781
9344843
|
NFATC1
|
CALM1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
8576111
8631904
10860980
9727000
8799126
|
CALM1
|
RAC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
22944912
21299499
21730051
9199170
|
CALM1
|
NFATC3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
8576111
8631904
10860980
9727000
8799126
|
RAC1
|
LCP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
17540168
11278486
11804587
12670394
|
ZAP70
|
LCP2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
8.0
|
1.0
|
ACSN
|
12415267
12731048
15735648
17371980
20814939
23620508
7600293
8642247
|
PLCG1
|
LCP2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
51.0
|
1.0
|
ACSN
|
10072481
10086337
10209041
10567412
10781611
10811803
10925299
10982827
11169415
11447289
11532940
11777939
11994416
12175651
12640133
1281218
12845332
14764585
15214048
15567848
15574420
16102570
16329184
16582911
16887996
1712101
17397400
17496910
17673906
19449109
19494291
19909365
23523669
23620508
24584707
25137453
2536067
25456276
25960930
26552706
7523143
7682895
7890616
8226994
8551221
8649391
8976179
8995379
9489702
9535722
9846483
|
LAT
|
LCP2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
51.0
|
1.0
|
ACSN
|
10072481
10086337
10209041
10567412
10781611
10811803
10925299
10982827
11169415
11447289
11532940
11777939
11994416
12175651
12640133
1281218
12845332
14764585
15214048
15567848
15574420
16102570
16329184
16582911
16887996
1712101
17397400
17496910
17673906
19449109
19494291
19909365
23523669
23620508
24584707
25137453
2536067
25456276
25960930
26552706
7523143
7682895
7890616
8226994
8551221
8649391
8976179
8995379
9489702
9535722
9846483
|
CD247
|
LCP2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
24.0
|
1.0
|
ACSN
|
10562324
10925299
11353765
11438547
11875494
12415267
12731048
12811837
15735648
16713974
17371980
20435894
20814939
21059766
23414611
23508573
23620508
23886063
24378531
7600293
8478617
8642247
9625766
9738502
|
LCP2
|
PRKCQ
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
10.0
|
1.0
|
ACSN
|
12640133
19909365
20189481
21536650
22786724
23474202
23620508
24343663
24584089
9765283
|
LCP2
|
VAV1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
10.0
|
1.0
|
ACSN
|
12640133
19909365
20189481
21536650
22786724
23474202
23620508
24343663
24584089
9765283
|
FYN
|
LCP2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
10648627
9047237
|
ZAP70
|
LCP2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
35.0
|
1.0
|
Omnipath
|
12817019
9047237
15388330
10660534
15286727
23109003
8892604
12640133
12640123
11323691
8702662
23758320
|
LCK
|
LCP2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
16354835
21725281
8702662
10648627
10556826
|
PTPN6
|
LCP2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
8760799
15588985
16189514
9765283
15668918
|
LCP2
|
PLCG1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
23331499
12941616
9341187
23109003
21725281
15929943
11709089
16467851
11390650
|
NFKB1
|
NFKBIA
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
ACSN
|
1829648
21725609
23178297
23572150
8096091
|
RELA
|
NFKBIA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
18204072
17876798
24083678
15499023
25759022
23422506
12859951
7775482
11744993
22723832
23450368
11060311
12885753
18981184
9250151
|
NFKB1
|
NFKBIA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
17876798
15499023
17709515
7775482
11744993
10454561
11060311
12885753
9250151
|
LCK
|
NFKBIA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
17.0
|
1.0
|
Omnipath
|
12432072
14534291
17570479
12429743
8797825
9792645
|
NFKB1
|
NFKBIA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
61.0
|
1.0
|
Omnipath
|
17145710
25609649
7862124
1340770
16210649
16970925
21719482
9738011
9865693
10497169
8657102
9572494
9315679
21988832
8887676
10329681
1829648
14743216
17003112
11313474
20558726
26496610
7867065
7891711
10837071
7831327
15836773
26186194
11571291
15214841
17561400
16846590
9566883
8096091
15371334
7479976
11020244
9426183
16493424
15145317
8631829
20237821
20980497
16513645
9597130
7479848
7739549
7628694
10655476
|
RELA
|
NFKBIA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
134.0
|
1.0
|
Omnipath
|
17145710
15657065
11801607
25609694
15226358
17003112
9057089
26496610
19219072
23850221
7831327
12927781
16683270
17301240
17561400
9566883
10391945
8887633
16209943
21719482
10066434
8657102
10581242
29734393
21988832
12419806
14743216
16105840
15671248
9751059
9990853
25759022
10498867
8246997
7878004
11020244
9426183
15845455
26476452
23563313
16951195
25520503
9694722
11287411
10329681
15799966
17612295
24457201
10085161
10837071
10969074
11571291
9573251
15214841
16846590
20065107
7479976
24248593
8887627
15145317
16493424
9135156
24634218
7479848
15024091
14636585
26463447
7862124
1340770
22081069
8139561
27923823
16970925
9738011
9865693
9572494
11231305
14685242
20797629
11313474
16226509
14690596
22022389
21217772
26186194
30213788
15371334
8978697
20980497
7739549
7628694
|
TRBV7-9
|
LCK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
22426112
16461343
2530588
|
HLA-DQA1
|
LCK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
22426112
16461343
2530588
|
TRAV8-4
|
LCK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
22426112
16461343
2530588
|
CD3D
|
LCK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
22426112
16461343
2530588
|
TRAV19
|
LCK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
22426112
16461343
2530588
|
TRBV12-3
|
LCK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
22426112
16461343
2530588
|
TRAC
|
LCK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
22426112
16461343
2530588
|
HLA-DQA2
|
LCK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
22426112
16461343
2530588
|
TRBC1
|
LCK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
22426112
16461343
2530588
|
TRAV29DV5
|
LCK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
22426112
16461343
2530588
|
HLA-DRA
|
LCK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
22426112
16461343
2530588
|
LCK
|
CD4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
16.0
|
1.0
|
ACSN
|
10398592
10652356
12731048
12740575
17544292
19290918
20814939
21127503
22513334
23620508
3263576
8478617
8986721
9438848
9738502
9751747
|
LCK
|
HLA-DPA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
22426112
16461343
2530588
|
LCK
|
CD3G
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
22426112
16461343
2530588
|
LCK
|
CD4
|
â—¼ PROTEIN_INTERACTION
|
|
|
16.0
|
1.0
|
ACSN
|
10398592
10652356
12731048
12740575
17544292
19290918
20814939
21127503
22513334
23620508
3263576
8478617
8986721
9438848
9738502
9751747
|
B2M
|
LCK
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
11.0
|
1.0
|
ACSN
|
10358761
10559964
11154916
11509172
11717192
14508489
16181333
22076556
22790179
24457417
8642276
|
LCK
|
PRKCQ
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
16.0
|
1.0
|
ACSN
|
10398592
10652356
12731048
12740575
17544292
19290918
20814939
21127503
22513334
23620508
3263576
8478617
8986721
9438848
9738502
9751747
|
LCK
|
ZAP70
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
15.0
|
1.0
|
ACSN
|
10652356
12731048
12740575
17544292
19290918
20814939
21127503
22513334
23620508
3263576
8478617
8986721
9438848
9738502
9751747
|
LCK
|
CD247
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
16.0
|
1.0
|
ACSN
|
10652356
11062502
12731048
12740575
15536084
17544292
19290918
20814939
21127503
22513334
23620508
8478617
8986721
9438848
9738502
9751747
|
LCK
|
FYN
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
9822663
15886116
10849438
12670394
|
LCK
|
VAV1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
16.0
|
1.0
|
ACSN
|
10398592
10652356
12731048
12740575
17544292
19290918
20814939
21127503
22513334
23620508
3263576
8478617
8986721
9438848
9738502
9751747
|
LCK
|
PTPRC
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
18.0
|
1.0
|
ACSN
|
10652356
12414720
12731048
12740575
17544292
19290918
20814939
21127503
22513334
23620508
23886063
25312647
3263576
8478617
8986721
9438848
9738502
9751747
|
CSK
|
LCK
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
7.0
|
1.0
|
ACSN
|
10790433
11181701
12485116
15713798
19290918
8011291
8986721
|
LCK
|
PTPRJ
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
2530588
|
LCK
|
PTPN6
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
12947224
15358536
18173375
18759926
|
CD4
|
LCK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
22.0
|
1.0
|
Omnipath
|
16888650
8104794
11854499
8246987
3262426
12601806
17653867
23109003
12007789
16189514
17005671
15489916
15047060
|
PTPRC
|
LCK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
31.0
|
1.0
|
Omnipath
|
17145710
19167335
8433999
2141684
9973453
8473339
2141630
12589038
8663450
15085197
2548204
8441403
11259588
15743820
10330160
2530588
10369126
8576115
7507203
11369760
17719247
|
PTPN22
|
LCK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
16461343
16111633
19167335
21719704
|
CD8A
|
LCK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
16818755
14500983
8814252
|
CSK
|
LCK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
56.0
|
1.0
|
Omnipath
|
20346773
19901323
10692391
11489946
22566970
24463463
2141684
16497976
15592455
20813252
10799545
14967142
27547268
24764511
28522807
16537894
12485116
8193535
24227778
17897955
8183556
22426112
89123626
15489916
14610046
23109003
18691976
28448599
17947241
1639064
12414720
15144186
27460989
24816556
22507872
8631775
15743820
25979654
8945479
11181701
27045023
25595912
15259016
|
LCK
|
PTPN6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
36.0
|
1.0
|
Omnipath
|
23071622
8692915
16231973
23109003
14699166
19167335
12459785
12468540
11294838
10574931
7512963
16497976
16189514
14757045
8114715
10488096
|
LCK
|
ZAP70
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
110.0
|
1.0
|
Omnipath
|
23874979
7961936
17579062
29073235
30992398
15292262
23933134
31932281
21829558
15592455
21917715
9199177
8798643
7612267
16339550
23331499
10202147
22238573
16189514
32184287
21103055
7642520
33531381
12648457
12522270
17998387
9685404
20945976
16839418
15144186
16461343
16094384
11270871
17192257
10037717
8756661
19606965
23758320
27869819
16111633
25137454
15268851
17942891
33482200
11514606
11514605
15659558
10556826
10318843
|
LCK
|
CD247
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
9047237
19229850
23109003
16461343
1706070
1505025
16337488
17979845
8626561
|
LCK
|
PRKCQ
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
22798961
26090489
17548359
10652356
|
LCK
|
LAT
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
16938345
12359715
12186560
27700984
|
LCK
|
CD3E
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
12522270
2470098
15144186
11855827
15592455
16094384
15659558
|
LCK
|
VAV1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
20.0
|
1.0
|
Omnipath
|
20028078
24332539
898671
16285729
15708849
17050525
15699036
17570479
11005864
10669745
10636924
|
CSK
|
FYN
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
7.0
|
1.0
|
ACSN
|
10790433
11181701
12485116
15713798
19290918
8011291
8986721
|
CSK
|
PTPRC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
7507203
19167335
|
CSK
|
FYN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
25.0
|
1.0
|
Omnipath
|
1985196
8262983
11489946
16537894
9647655
25720756
18691976
10366594
19369195
1533589
1699196
7524477
16713569
15713745
14967142
|
HLA-DQA1
|
CD247
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
22426112
16461343
2530588
|
CD1D
|
CD247
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
Reactome
|
18037897
26300885
15864273
14764708
20080535
15723809
7542404
21167756
22006319
25703557
|
HLA-DQA2
|
CD247
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
22426112
16461343
2530588
|
CD4
|
CD247
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
22426112
16461343
2530588
|
HLA-DPA1
|
CD247
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
22426112
16461343
2530588
|
HLA-DRA
|
CD247
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
22426112
16461343
2530588
|
CD1A
|
CD247
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
Reactome
|
18037897
26300885
15864273
14764708
20080535
15723809
7542404
21167756
22006319
25703557
|
CD247
|
CD1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
Reactome
|
18037897
26300885
15864273
14764708
20080535
15723809
7542404
21167756
22006319
25703557
|
CD247
|
ZAP70
|
â—¼ PHYSICAL_INTERACTION
|
|
|
36.0
|
1.0
|
ACSN
|
10358164
10562324
10925299
11353765
11438547
11449354
11875494
12393695
12415267
12731048
12811837
15081523
15099567
15735648
16713974
17371980
18768831
20435894
20814939
21059766
2139103
23414611
23508573
23620508
23886063
24378531
24445665
7523143
7600293
8344348
8478617
8551221
8642247
9603467
9625766
9738502
|
CD247
|
B2M
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
Reactome
|
18037897
26300885
15864273
14764708
20080535
15723809
7542404
21167756
22006319
25703557
|
CD247
|
CD1C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
Reactome
|
18037897
26300885
15864273
14764708
20080535
15723809
7542404
21167756
22006319
25703557
|
CD247
|
ZAP70
|
â—¼ SHARES_COMPLEX
|
|
|
36.0
|
1.0
|
ACSN
|
10358164
10562324
10925299
11353765
11438547
11449354
11875494
12393695
12415267
12731048
12811837
15081523
15099567
15735648
16713974
17371980
18768831
20435894
20814939
21059766
2139103
23414611
23508573
23620508
23886063
24378531
24445665
7523143
7600293
8344348
8478617
8551221
8642247
9603467
9625766
9738502
|
FYN
|
CD247
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
15.0
|
1.0
|
ACSN
|
10591186
10648627
11062502
12218089
12731048
15536084
19290918
19909365
20814939
21378271
22683124
22863785
24440149
27192565
9738502
|
B2M
|
CD247
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
11.0
|
1.0
|
ACSN
|
10358761
10559964
11154916
11509172
11717192
14508489
16181333
22076556
22790179
24457417
8642276
|
CD4
|
CD247
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
16.0
|
1.0
|
ACSN
|
10398592
10652356
12731048
12740575
17544292
19290918
20814939
21127503
22513334
23620508
3263576
8478617
8986721
9438848
9738502
9751747
|
CD247
|
PLCG1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
24.0
|
1.0
|
ACSN
|
10562324
10925299
11353765
11438547
11875494
12415267
12731048
12811837
15735648
16713974
17371980
20435894
20814939
21059766
23414611
23508573
23620508
23886063
24378531
7600293
8478617
8642247
9625766
9738502
|
CD247
|
ZAP70
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
36.0
|
1.0
|
ACSN
|
10358164
10562324
10925299
11353765
11438547
11449354
11875494
12393695
12415267
12731048
12811837
15081523
15099567
15735648
16713974
17371980
18768831
20435894
20814939
21059766
2139103
23414611
23508573
23620508
23886063
24378531
24445665
7523143
7600293
8344348
8478617
8551221
8642247
9603467
9625766
9738502
|
CD247
|
PTPRC
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
ACSN
|
12414720
19290918
23620508
23886063
25312647
|
CD247
|
LAT
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
24.0
|
1.0
|
ACSN
|
10562324
10925299
11353765
11438547
11875494
12415267
12731048
12811837
15735648
16713974
17371980
20435894
20814939
21059766
23414611
23508573
23620508
23886063
24378531
7600293
8478617
8642247
9625766
9738502
|
PTPRC
|
CD247
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
2530588
|
CD247
|
PTPN6
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
12947224
15358536
18173375
18759926
|
CD247
|
PTPRJ
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
2530588
|
PTPN22
|
CD247
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
16461343
|
PTPN6
|
CD247
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
14672952
11238643
23109003
|
FYN
|
CD247
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
8578591
12522270
7589084
9677202
9047237
15144186
1454062
1530920
15592455
16094384
9368621
16713569
96108162
15659558
8760790
|
CD247
|
ZAP70
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
74.0
|
1.0
|
Omnipath
|
11449354
10752619
8906806
18768831
2139103
8551221
23886063
9185620
12415267
10358158
10704231
8648092
7528772
7737297
11875494
15832366
15081523
24445665
9603467
17371980
21957439
8344348
7600293
7509083
7523143
15099567
10925299
9625766
8642247
9036949
8901551
16189514
21059766
9738502
12393695
24378531
20814939
23109003
9295038
8366117
11438547
26390156
23414611
23620508
8478617
20435894
7761456
15268851
16713974
26192618
12731048
10562324
20637659
7522230
12811837
11353765
23508573
10358164
15735648
|
PLCG1
|
LAT
|
â—¼ PHYSICAL_INTERACTION
|
|
|
51.0
|
1.0
|
ACSN
|
10072481
10086337
10209041
10567412
10781611
10811803
10925299
10982827
11169415
11447289
11532940
11777939
11994416
12175651
12640133
1281218
12845332
14764585
15214048
15567848
15574420
16102570
16329184
16582911
16887996
1712101
17397400
17496910
17673906
19449109
19494291
19909365
23523669
23620508
24584707
25137453
2536067
25456276
25960930
26552706
7523143
7682895
7890616
8226994
8551221
8649391
8976179
8995379
9489702
9535722
9846483
|
LAT
|
RAC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
17540168
11278486
11804587
12670394
|
PLCG1
|
LAT
|
â—¼ SHARES_COMPLEX
|
|
|
51.0
|
1.0
|
ACSN
|
10072481
10086337
10209041
10567412
10781611
10811803
10925299
10982827
11169415
11447289
11532940
11777939
11994416
12175651
12640133
1281218
12845332
14764585
15214048
15567848
15574420
16102570
16329184
16582911
16887996
1712101
17397400
17496910
17673906
19449109
19494291
19909365
23523669
23620508
24584707
25137453
2536067
25456276
25960930
26552706
7523143
7682895
7890616
8226994
8551221
8649391
8976179
8995379
9489702
9535722
9846483
|
PLCG1
|
LAT
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
51.0
|
1.0
|
ACSN
|
10072481
10086337
10209041
10567412
10781611
10811803
10925299
10982827
11169415
11447289
11532940
11777939
11994416
12175651
12640133
1281218
12845332
14764585
15214048
15567848
15574420
16102570
16329184
16582911
16887996
1712101
17397400
17496910
17673906
19449109
19494291
19909365
23523669
23620508
24584707
25137453
2536067
25456276
25960930
26552706
7523143
7682895
7890616
8226994
8551221
8649391
8976179
8995379
9489702
9535722
9846483
|
ZAP70
|
LAT
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
8.0
|
1.0
|
ACSN
|
12415267
12731048
15735648
17371980
20814939
23620508
7600293
8642247
|
VAV1
|
LAT
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
33.0
|
1.0
|
ACSN
|
10077632
10646608
10679059
10714681
10849438
10898494
11080163
11526404
11698448
11754814
11994416
12094222
12165654
12186560
12616499
12626562
12740575
12885870
12917349
14764585
15169881
16887996
19909365
20189481
22513334
22786724
22952938
25355530
25539813
26552706
8189062
8226994
9438848
|
ZAP70
|
LAT
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
27.0
|
1.0
|
Omnipath
|
24412752
15659558
10811803
27896837
11395491
15084594
16906159
15029250
27700984
12496416
34161759
11368773
30510001
23109003
22507872
18779373
33931484
23758320
15100278
24642916
23150273
|
CD8A
|
LAT
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
10562325
|
PTPRJ
|
LAT
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
11259588
|
LAT
|
PLCG1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
29.0
|
1.0
|
Omnipath
|
27221712
11368773
9489702
12941616
15286727
10811803
23109003
24642916
16938345
11709089
16713569
15219999
16467851
9729044
|
LAT
|
VAV1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
11368773
23109003
16713569
12186560
|
VAV1
|
PLCG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
11007481
8986718
10395673
9099726
|
ZAP70
|
PLCG1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
24.0
|
1.0
|
ACSN
|
10562324
10925299
11353765
11438547
11875494
12415267
12731048
12811837
15735648
16713974
17371980
20435894
20814939
21059766
23414611
23508573
23620508
23886063
24378531
7600293
8478617
8642247
9625766
9738502
|
VAV1
|
PLCG1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
33.0
|
1.0
|
ACSN
|
10077632
10646608
10679059
10714681
10849438
10898494
11080163
11526404
11698448
11754814
11994416
12094222
12165654
12186560
12616499
12626562
12740575
12885870
12917349
14764585
15169881
16887996
19909365
20189481
22513334
22786724
22952938
25355530
25539813
26552706
8189062
8226994
9438848
|
PRKCA
|
PLCG1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
2820980
8885868
10592173
1370476
|
FYN
|
PLCG1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
8395016
10586033
7682059
16713569
|
VAV1
|
PLCG1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
67.0
|
1.0
|
Omnipath
|
11340169
10849438
22952938
9099726
12626562
12917349
12165654
16713569
25539813
8673706
19909365
7518558
10077632
11278486
26552706
10395673
12885870
12573241
8629002
11526404
10898494
25355530
17050525
10592173
11698448
10646608
11094073
11994416
20189481
12670394
9550384
12616499
22513334
10679059
23109003
9891995
11007481
12740575
17540168
11804587
8630736
17054426
11754814
8986718
9438848
11080163
29145629
12941616
10714681
14764585
15169881
26192618
22786724
8226994
15010370
12094222
8189062
16887996
11709089
16467851
24243840
12186560
|
PTPRJ
|
PLCG1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
11259588
|
PLCG1
|
SOS1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
26.0
|
1.0
|
Omnipath
|
15953601
12084069
7629168
9020117
16713569
10913276
17474147
10940929
|
GRAP2
|
VAV1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
11007481
8986718
10395673
9099726
|
VAV1
|
SOS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
11007481
8986718
10395673
9099726
|
FYN
|
VAV1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
15.0
|
1.0
|
ACSN
|
10591186
10648627
12218089
12731048
15699036
19290918
19909365
20814939
21378271
22683124
22863785
24440149
27192565
9738502
9822663
|
PTPN6
|
VAV1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
13.0
|
1.0
|
ACSN
|
12176909
12773515
12917349
15240681
15713798
22513334
22952938
25355530
26667266
27474009
8976179
8986721
9765283
|
CD4
|
VAV1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
16.0
|
1.0
|
ACSN
|
10398592
10652356
12731048
12740575
17544292
19290918
20814939
21127503
22513334
23620508
3263576
8478617
8986721
9438848
9738502
9751747
|
ZAP70
|
VAV1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
10395678
23109003
14757747
15751964
7798261
16189514
11859198
23758320
16339550
|
PTPN6
|
VAV1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
8632004
10592173
16189514
|
FYN
|
VAV1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
11262396
15699036
11005864
9438848
16713569
15933714
9822663
|
VAV1
|
RAC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
8990121
9601639
32203420
11790798
10727406
18488041
23525006
11287617
10592173
10744696
16397238
18511940
|
VAV1
|
HRAS
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
8554611
16713569
8289830
|
VAV1
|
PRKCQ
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
23331499
11956228
23109003
10725744
15802604
14673152
21487479
|
CD4
|
PTPN6
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
12947224
15358536
18173375
18759926
|
TRAC
|
PTPN6
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
12947224
15358536
18173375
18759926
|
TRBV12-3
|
PTPN6
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
12947224
15358536
18173375
18759926
|
CD3D
|
PTPN6
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
12947224
15358536
18173375
18759926
|
HLA-DPA1
|
PTPN6
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
12947224
15358536
18173375
18759926
|
TRAV19
|
PTPN6
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
12947224
15358536
18173375
18759926
|
HLA-DRA
|
PTPN6
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
12947224
15358536
18173375
18759926
|
CD3G
|
PTPN6
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
12947224
15358536
18173375
18759926
|
HLA-DQA1
|
PTPN6
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
12947224
15358536
18173375
18759926
|
TRAV8-4
|
PTPN6
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
12947224
15358536
18173375
18759926
|
TRBC1
|
PTPN6
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
12947224
15358536
18173375
18759926
|
CD3E
|
PTPN6
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
12947224
15358536
18173375
18759926
|
TRAV29DV5
|
PTPN6
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
12947224
15358536
18173375
18759926
|
TRBV7-9
|
PTPN6
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
12947224
15358536
18173375
18759926
|
HLA-DQA2
|
PTPN6
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
12947224
15358536
18173375
18759926
|
PRKCA
|
PTPN6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
15269224
11781100
25876760
|
PTPN6
|
ZAP70
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
12763134
23109003
8638162
23180781
16189514
10458769
|
FYN
|
PTPRC
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
17.0
|
1.0
|
ACSN
|
10591186
10648627
12218089
12414720
12731048
19290918
19909365
20814939
21378271
22683124
22863785
23620508
23886063
24440149
25312647
27192565
9738502
|
PTPRC
|
FYN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
1985196
8980254
11909961
1464315
1533589
9535845
16713569
9368621
12589038
|
FYN
|
ZAP70
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
7760813
16713569
16839418
|
FYN
|
SOS1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
17474147
16713569
9856337
|
FYN
|
PRKCQ
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
10383400
16713569
|
HRAS
|
RAF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
1.0
|
STRING
|
36370105
|
RAF1
|
HRAS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
14.0
|
1.0
|
ACSN
|
10358164
11532940
12566895
14764585
15516985
16102570
19289794
19565474
24027568
7510700
8551221
9069260
9763606
9846483
|
RAF1
|
RASGRP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
19.0
|
1.0
|
ACSN
|
10567412
10807788
11532940
12419216
12566895
12782630
14764585
15184873
15516985
15567848
16227978
16488589
17496910
19289794
19565474
19615955
21102635
24027568
9069260
|
RAF1
|
RASGRP1
|
â—¼ SHARES_COMPLEX
|
|
|
19.0
|
1.0
|
ACSN
|
10567412
10807788
11532940
12419216
12566895
12782630
14764585
15184873
15516985
15567848
16227978
16488589
17496910
19289794
19565474
19615955
21102635
24027568
9069260
|
RAF1
|
HRAS
|
â—¼ SHARES_COMPLEX
|
|
|
14.0
|
1.0
|
ACSN
|
10358164
11532940
12566895
14764585
15516985
16102570
19289794
19565474
24027568
7510700
8551221
9069260
9763606
9846483
|
FOS
|
RAF1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
11.0
|
1.0
|
ACSN
|
11274345
12738796
15067049
16393692
16394015
18039929
19667062
21385848
22634314
23430059
9064320
|
JUN
|
RAF1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
ACSN
|
11274345
12738796
17439715
18039929
26587781
8545107
|
RAF1
|
HRAS
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
14.0
|
1.0
|
ACSN
|
10358164
11532940
12566895
14764585
15516985
16102570
19289794
19565474
24027568
7510700
8551221
9069260
9763606
9846483
|
HRAS
|
RAF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
147.0
|
1.0
|
Omnipath
|
17145710
18273062
9523700
1639773
8601312
19595761
20133694
11032808
9154803
10882715
14654780
1996324
19222999
16301319
11948414
8530446
7969158
11313862
9150145
20080631
1990291
12750173
15031288
12932319
9665134
8805624
8340422
1386920
23331499
16916524
16041367
23180781
18988627
20178605
15688026
15664191
22169110
11733498
7862125
8180183
19063885
12391160
9144171
8035810
9020159
14724584
19696784
21779497
9261098
12173045
12620389
8628317
19914712
1708096
19933846
26721396
7730360
10205168
8332187
16803888
18775988
12917261
9099670
10545207
25684575
8670882
10783161
12379659
10887184
17569879
21071413
8332195
7523381
10531446
24929361
8503013
16093354
19541618
10369681
8911690
18073111
11136732
10922060
7760835
11134016
|
PRKCB
|
RAF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
8288587
1386920
12917261
22826029
|
PRKCA
|
RAF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
27.0
|
1.0
|
Omnipath
|
1386920
23331499
9447975
8321321
12551925
8288587
7935389
12917261
9922370
15664191
93309588
1437148
|
RAF1
|
MAP2K1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
143.0
|
1.0
|
Omnipath
|
10757792
18337766
18799465
15342917
23728975
26496610
15866172
17053865
11242034
9351825
9677429
8157000
7992057
11948414
11604401
16129686
10677502
12695496
19197339
7565670
12750173
7936666
1326789
19219045
23331499
18556463
10976102
18988627
15485920
15175348
18691976
16407412
10409742
9311917
17192257
7898932
8621729
23934108
11684694
21336309
7624324
12920017
11948406
15466214
11042690
12907640
9032297
27169363
12876277
8933152
8223433
8248196
8131746
12594221
10969079
10567369
17979178
17724343
24746704
19058874
10958680
8090753
21071413
7731720
7873542
1330321
8503013
16093354
19541618
8394352
15466476
25155755
11136732
9069260
94178255
8607979
10327068
10359597
8039496
20212043
|
RASGRP1
|
HRAS
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
ACSN
|
10807788
12782630
14764585
15184873
17496910
24027568
|
HRAS
|
SOS1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
11.0
|
1.0
|
Reactome
|
19946327
11429702
11157491
18757403
21666749
21711248
18381441
19103595
21160078
9857065
20179196
|
SOS1
|
HRAS
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
41.0
|
1.0
|
Omnipath
|
12628188
10208427
16713569
10913276
23331499
18454158
15507210
10592173
17673906
17496910
26721396
20133692
19141281
23132018
11560935
9447984
9690470
17084389
|
HRAS
|
PIK3CG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
9069260
9727023
17145710
10922060
11136978
21779497
|
HRAS
|
MAPK8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
11525649
8137421
16810318
16713569
|
HRAS
|
PIK3CA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
20.0
|
1.0
|
Omnipath
|
9069260
9113989
8052307
24412244
17540175
9931431
11313862
14724584
10592173
9150145
8665852
10783161
|
JUN
|
FOS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
21.0
|
1.0
|
ACSN
|
10606235
11274345
11274400
14673140
15067049
16393692
16394015
17439715
18222063
18754863
19667062
19846528
21385848
21790308
22381618
22634314
22723415
23430059
26587781
8545107
9064320
|
JUN
|
FOS
|
â—¼ PROTEIN_INTERACTION
|
|
|
21.0
|
1.0
|
ACSN
|
10606235
11274345
11274400
14673140
15067049
16393692
16394015
17439715
18222063
18754863
19667062
19846528
21385848
21790308
22381618
22634314
22723415
23430059
26587781
8545107
9064320
|
JUN
|
FOS
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
24.0
|
1.0
|
Omnipath
|
2513130
14561487
8617996
8934539
19255142
9217081
12760745
2498806
10521486
8597411
10858536
12392213
9819441
1380150
23562910
1944274
9867253
9571041
1900040
2511006
14684847
15467742
12231642
11950097
|
FOS
|
JUN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
73.0
|
1.0
|
Omnipath
|
20498278
16714286
21675959
25609649
23602568
9872330
20102225
8380166
18848838
18535250
2516828
8397339
15867431
18172215
9346889
10779323
9732876
16928824
26496610
15994313
22719067
24029232
16511568
20195357
11053448
20936779
26186194
18619508
20511396
16008525
10488148
21199371
8617242
17440114
16055710
15319445
11090181
9160889
23661758
1631061
15718494
11431474
31515488
8440710
7816143
20410304
34671206
|
RELA
|
JUN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
18174238
9468519
16713569
10488148
|
MAPK8
|
JUN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
202.0
|
1.0
|
Omnipath
|
17143273
17804415
10617656
8846788
15958389
11948398
10882101
20028971
12697749
15894542
20514406
14612408
17875713
9891069
17570479
18922473
11809792
8586671
11896587
12185592
12871843
7992057
7600582
11278395
8137421
8001819
10493750
14557262
16549498
18707149
9169478
11460167
15289320
8157646
16007099
20506250
22110360
15378002
9687508
12740383
20732415
9305638
19270716
23331499
10747973
16291755
16393692
12832416
18988627
10713700
18669648
12087092
14633987
8525045
15677475
16076903
16166642
18650425
15590691
1608942
19910486
18212344
11562357
12228228
16740711
14701799
19690332
10871633
12531896
16713569
8654373
16983342
19664995
15302935
10962563
15068801
8621542
8607977
18362184
10393177
20068231
9808624
14572659
8224842
10585392
9407028
17363973
19527717
19436832
14517282
12407442
9487126
9692890
14523011
15212693
10908726
11108663
13130464
10064600
18429822
15299005
9774977
11907583
12963725
16824735
19413330
10617104
17055484
21071413
18452278
16434970
16157600
7737130
23816567
10987838
17189706
9561845
9575168
1460037
7652575
18617513
24113186
11971971
11801649
25098452
20058876
16533805
9184210
18003900
9315636
10385525
18957422
12881422
11274345
12052834
15749833
|
NFATC1
|
PPP3CB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
8576111
8631904
10860980
9727000
8799126
|
PPP3CB
|
NFATC3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
8576111
8631904
10860980
9727000
8799126
|
NFKB1
|
RELA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
1.0
|
STRING
|
36370105
|
RELA
|
NFKB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
16778171
20427719
23362108
16513645
1740105
20596645
16513841
19469019
8454856
21420936
16135789
9417120
|
NFKB1
|
RELA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
88.0
|
1.0
|
Omnipath
|
17145710
16209943
25609649
8428580
12947093
16970925
17072323
2050119
15657065
21270162
11976329
16793322
21544861
22261743
8657102
9824778
11880271
9450761
17962807
21988832
25355951
9722548
18215660
14743216
15799966
10799898
16105840
15218526
8798655
14690596
22139845
22808155
11571291
17072327
16740634
10498867
8255759
8246997
15214841
16846590
15371334
16285893
17072322
17855547
18321863
16493424
7479976
15145317
17561400
20110362
9426183
23687337
12414801
11970949
20154269
20237821
24175631
24634218
34100597
14645533
17982102
21763497
16204234
9437432
20547752
15818410
7628694
|
MAP3K1
|
MAP2K4
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
41.0
|
1.0
|
ACSN
|
10086337
10465784
10567412
10811803
10982827
11274345
11447289
11668179
11777939
12040186
12048245
12175651
12419216
12640133
12738796
12782630
14585353
15170913
15567848
15574420
15863030
16102570
16227978
16488589
16582911
16887996
17496910
17496911
17673906
18855897
19449109
19568798
19615955
21102635
21614932
24027568
26552706
7510700
8551221
9379049
9582321
|
RAC1
|
MAP3K1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
7600581
9487126
7992057
7600582
9733714
9305638
|
MAP3K1
|
MAP2K1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
8385802
12048245
8131746
17110930
8034665
8019005
10969079
12456688
|
MAP3K1
|
MAP2K4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
83.0
|
1.0
|
Omnipath
|
17145710
15863030
8551221
10811803
11447289
16582911
11777939
18855897
9379049
16472679
12640133
12040186
9305638
26552706
23331499
12048245
10982827
16227978
11668179
23180781
21614932
9808624
12738796
12782630
9889102
9891069
10567412
12175651
18182252
19568798
16102570
9582321
14585353
10521444
17673906
17496910
11242034
10465784
7510700
9712898
11274345
12419216
7992057
7600582
10086337
17276500
15574420
19449109
26192618
19615955
19369195
24027568
10400627
16887996
8910292
12456688
9487126
21102635
15567848
17496911
16488589
15170913
|
MAP3K1
|
MAPK8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
12228228
9405400
25241761
10465784
15757900
15299005
14500727
21152872
26538579
|
GRAP2
|
RAC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
17540168
11278486
11804587
12670394
|
PRKCA
|
RAC1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
ACSN
|
10679481
10871288
16492141
18851840
20027184
21474067
|
RAC1
|
MAP2K4
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
32.0
|
1.0
|
ACSN
|
10086337
10567412
10811803
10982827
11274345
11447289
11756498
11777939
12040186
12175651
12640133
12738796
14585353
15567848
15574420
15863030
16102570
16582911
16887996
17496910
17673906
18000759
18855897
19151919
19449109
19568798
21614932
24027568
26552706
27331412
7510700
8551221
|
PRKCA
|
RAC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
16628218
20027184
11284700
18851840
21474067
|
RAC1
|
MAP2K4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
17496910
18000759
15574420
19151919
10727406
11777939
18855897
21614932
12738796
11274345
12040186
19568798
14585353
11562357
|
RAC1
|
MAPK8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
17251915
12213839
18423204
18426980
10592173
22252525
10930450
|
RAC1
|
MAP2K1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
17496910
18000759
15574420
19151919
11777939
18855897
21614932
12738796
11274345
12040186
19568798
14585353
|
CD4
|
ZAP70
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
16.0
|
1.0
|
ACSN
|
10398592
10652356
12731048
12740575
17544292
19290918
20814939
21127503
22513334
23620508
3263576
8478617
8986721
9438848
9738502
9751747
|
PTPN22
|
ZAP70
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
16461343
15659558
|
CD3E
|
ZAP70
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
7761456
8906806
21900181
8366117
11855827
9698567
17617578
|
CD3D
|
B2M
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
Reactome
|
18037897
26300885
15864273
14764708
20080535
15723809
7542404
21167756
22006319
25703557
|
CD3E
|
B2M
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
Reactome
|
18037897
26300885
15864273
14764708
20080535
15723809
7542404
21167756
22006319
25703557
|
TRAV29DV5
|
B2M
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
Reactome
|
18037897
26300885
15864273
14764708
20080535
15723809
7542404
21167756
22006319
25703557
|
TRAV19
|
B2M
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
Reactome
|
18037897
26300885
15864273
14764708
20080535
15723809
7542404
21167756
22006319
25703557
|
TRAV8-4
|
B2M
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
Reactome
|
18037897
26300885
15864273
14764708
20080535
15723809
7542404
21167756
22006319
25703557
|
TRAC
|
B2M
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
Reactome
|
18037897
26300885
15864273
14764708
20080535
15723809
7542404
21167756
22006319
25703557
|
CD3G
|
B2M
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
Reactome
|
18037897
26300885
15864273
14764708
20080535
15723809
7542404
21167756
22006319
25703557
|
TRBC1
|
B2M
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
Reactome
|
18037897
26300885
15864273
14764708
20080535
15723809
7542404
21167756
22006319
25703557
|
TRBV12-3
|
B2M
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
Reactome
|
18037897
26300885
15864273
14764708
20080535
15723809
7542404
21167756
22006319
25703557
|
TRBV7-9
|
B2M
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
Reactome
|
18037897
26300885
15864273
14764708
20080535
15723809
7542404
21167756
22006319
25703557
|
B2M
|
PTPRC
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
11.0
|
1.0
|
ACSN
|
10358761
10559964
11154916
11509172
11717192
14508489
16181333
22076556
22790179
24457417
8642276
|
TRAV19
|
CD4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
22426112
16461343
2530588
|
CD4
|
TRBV7-9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
22426112
16461343
2530588
|
CD4
|
HLA-DQA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
22426112
16461343
2530588
|
CD4
|
CD3D
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
22426112
16461343
2530588
|
CD4
|
HLA-DRA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
22426112
16461343
2530588
|
CD4
|
HLA-DQA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
22426112
16461343
2530588
|
CD4
|
TRAV8-4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
22426112
16461343
2530588
|
CD4
|
CD3G
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
22426112
16461343
2530588
|
CD4
|
TRBC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
22426112
16461343
2530588
|
CD4
|
TRBV12-3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
22426112
16461343
2530588
|
CD4
|
TRAV29DV5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
22426112
16461343
2530588
|
CD4
|
TRAC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
22426112
16461343
2530588
|
CD4
|
HLA-DPA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
22426112
16461343
2530588
|
CD4
|
CD3E
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
22426112
16461343
2530588
|
CD4
|
PRKCQ
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
16.0
|
1.0
|
ACSN
|
10398592
10652356
12731048
12740575
17544292
19290918
20814939
21127503
22513334
23620508
3263576
8478617
8986721
9438848
9738502
9751747
|
CD4
|
PTPRC
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
16.0
|
1.0
|
ACSN
|
10398592
10652356
12731048
12740575
17544292
19290918
20814939
21127503
22513334
23620508
3263576
8478617
8986721
9438848
9738502
9751747
|
CD4
|
PTPRJ
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
2530588
|
CD4
|
PTPRC
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
2530588
|
ELK1
|
PRKCA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
26010542
16297876
|
MAPK8
|
ELK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
27.0
|
1.0
|
Omnipath
|
8846788
20506250
8654373
20028971
23331499
17875713
16393692
10637505
26538579
8586671
9501095
26370088
7889942
19436832
7651411
11274345
|
PRKCA
|
NFATC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
12351631
9072970
|
HLA-DQA2
|
PTPRC
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
2530588
|
TRBC1
|
PTPRC
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
2530588
|
HLA-DRA
|
PTPRC
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
2530588
|
TRAV19
|
PTPRC
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
2530588
|
HLA-DQA1
|
PTPRC
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
2530588
|
TRAV8-4
|
PTPRC
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
2530588
|
TRBV7-9
|
PTPRC
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
2530588
|
CD3D
|
PTPRC
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
2530588
|
CD3E
|
PTPRC
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
2530588
|
TRAC
|
PTPRC
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
2530588
|
TRBV12-3
|
PTPRC
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
2530588
|
TRAV29DV5
|
PTPRC
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
2530588
|
PTPRC
|
HLA-DPA1
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
2530588
|
PTPRC
|
CD3G
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
2530588
|
TRBV12-3
|
HLA-DRA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
22426112
16461343
2530588
|
TRBC1
|
HLA-DRA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
22426112
16461343
2530588
|
TRAV8-4
|
HLA-DRA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
22426112
16461343
2530588
|
TRAC
|
HLA-DRA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
22426112
16461343
2530588
|
TRAV19
|
HLA-DRA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
22426112
16461343
2530588
|
HLA-DRA
|
TRBV7-9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
22426112
16461343
2530588
|
HLA-DRA
|
CD3E
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
22426112
16461343
2530588
|
HLA-DRA
|
CD3D
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
22426112
16461343
2530588
|
HLA-DRA
|
TRAV29DV5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
22426112
16461343
2530588
|
HLA-DRA
|
CD3G
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
22426112
16461343
2530588
|
HLA-DRA
|
PTPRJ
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
2530588
|
MAP2K4
|
MAPK8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
91.0
|
1.0
|
Omnipath
|
17143273
10713157
11489946
7600581
8702918
17145710
13130464
23416355
10748139
8805275
18855897
10791986
9108083
19690332
95141073
18083107
9724739
12788955
9305638
23331499
19534553
15068801
7839144
10958661
21071413
23047924
11062067
21614932
9808624
12738796
15911620
15998799
9891069
11389443
18988627
9733714
11847100
18669648
16153436
10521444
15302099
16282370
11242034
14523011
12709432
26370088
9661668
10499589
7652575
16076903
7992057
16440308
7600582
17192257
9860979
15755722
12133933
16533805
19369195
9312068
9207092
10385525
12354380
12917261
8910292
9487126
9448004
10962008
12624093
11274345
11099046
|
MAPK8
|
NFATC3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
14517246
16648474
10978313
23047924
9374467
9630228
11274345
|
HLA-DQA1
|
CD3D
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
22426112
16461343
2530588
|
HLA-DQA2
|
CD3D
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
22426112
16461343
2530588
|
CD3D
|
HLA-DPA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
22426112
16461343
2530588
|
CD3D
|
CD1D
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
Reactome
|
18037897
26300885
15864273
14764708
20080535
15723809
7542404
21167756
22006319
25703557
|
CD3D
|
CD1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
Reactome
|
18037897
26300885
15864273
14764708
20080535
15723809
7542404
21167756
22006319
25703557
|
CD3D
|
CD1C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
Reactome
|
18037897
26300885
15864273
14764708
20080535
15723809
7542404
21167756
22006319
25703557
|
CD3D
|
CD1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
Reactome
|
18037897
26300885
15864273
14764708
20080535
15723809
7542404
21167756
22006319
25703557
|
CD3D
|
PTPRJ
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
2530588
|
HLA-DQA2
|
CD3E
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
22426112
16461343
2530588
|
CD1A
|
CD3E
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
Reactome
|
18037897
26300885
15864273
14764708
20080535
15723809
7542404
21167756
22006319
25703557
|
HLA-DQA1
|
CD3E
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
22426112
16461343
2530588
|
CD3E
|
HLA-DPA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
22426112
16461343
2530588
|
CD3E
|
CD1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
Reactome
|
18037897
26300885
15864273
14764708
20080535
15723809
7542404
21167756
22006319
25703557
|
CD3E
|
CD1C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
Reactome
|
18037897
26300885
15864273
14764708
20080535
15723809
7542404
21167756
22006319
25703557
|
CD3E
|
CD1D
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
Reactome
|
18037897
26300885
15864273
14764708
20080535
15723809
7542404
21167756
22006319
25703557
|
CD3E
|
PTPRJ
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
2530588
|
PPP3CA
|
NFATC3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
8576111
8631904
10860980
9727000
8799126
|
PPP3CA
|
NFATC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
10860980
24954618
19285944
21880741
23468591
14722106
16407284
23015147
15276472
|
PPP3CA
|
NFATC3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
10860980
21880741
12594826
11509611
16407284
|
TRAC
|
HLA-DQA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
22426112
16461343
2530588
|
TRAV19
|
HLA-DQA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
22426112
16461343
2530588
|
TRAV8-4
|
HLA-DQA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
22426112
16461343
2530588
|
TRBV12-3
|
HLA-DQA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
22426112
16461343
2530588
|
TRBC1
|
HLA-DQA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
22426112
16461343
2530588
|
HLA-DQA1
|
CD3G
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
22426112
16461343
2530588
|
HLA-DQA1
|
TRAV29DV5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
22426112
16461343
2530588
|
HLA-DQA1
|
TRBV7-9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
22426112
16461343
2530588
|
HLA-DQA1
|
PTPRJ
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
2530588
|
TRAV8-4
|
HLA-DQA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
22426112
16461343
2530588
|
TRBV12-3
|
HLA-DQA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
22426112
16461343
2530588
|
TRBC1
|
HLA-DQA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
22426112
16461343
2530588
|
TRAV19
|
HLA-DQA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
22426112
16461343
2530588
|
TRAC
|
HLA-DQA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
22426112
16461343
2530588
|
HLA-DQA2
|
TRAV29DV5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
22426112
16461343
2530588
|
HLA-DQA2
|
CD3G
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
22426112
16461343
2530588
|
HLA-DQA2
|
TRBV7-9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
22426112
16461343
2530588
|
HLA-DQA2
|
PTPRJ
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
2530588
|
TRBV7-9
|
HLA-DPA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
22426112
16461343
2530588
|
TRAV19
|
HLA-DPA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
22426112
16461343
2530588
|
TRBC1
|
HLA-DPA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
22426112
16461343
2530588
|
TRBV12-3
|
HLA-DPA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
22426112
16461343
2530588
|
TRAV8-4
|
HLA-DPA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
22426112
16461343
2530588
|
TRAC
|
HLA-DPA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
22426112
16461343
2530588
|
TRAV29DV5
|
HLA-DPA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
22426112
16461343
2530588
|
CD3G
|
HLA-DPA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
22426112
16461343
2530588
|
HLA-DPA1
|
PTPRJ
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
2530588
|
TRAV8-4
|
PTPRJ
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
2530588
|
TRAC
|
PTPRJ
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
2530588
|
CD3G
|
PTPRJ
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
2530588
|
TRBV7-9
|
PTPRJ
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
2530588
|
TRBV12-3
|
PTPRJ
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
2530588
|
TRAV29DV5
|
PTPRJ
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
2530588
|
TRBC1
|
PTPRJ
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
2530588
|
TRAV19
|
PTPRJ
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
2530588
|
TRBC1
|
CD1D
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
Reactome
|
18037897
26300885
15864273
14764708
20080535
15723809
7542404
21167756
22006319
25703557
|
TRAV29DV5
|
CD1D
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
Reactome
|
18037897
26300885
15864273
14764708
20080535
15723809
7542404
21167756
22006319
25703557
|
TRAV8-4
|
CD1D
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
Reactome
|
18037897
26300885
15864273
14764708
20080535
15723809
7542404
21167756
22006319
25703557
|
CD3G
|
CD1D
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
Reactome
|
18037897
26300885
15864273
14764708
20080535
15723809
7542404
21167756
22006319
25703557
|
TRBV7-9
|
CD1D
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
Reactome
|
18037897
26300885
15864273
14764708
20080535
15723809
7542404
21167756
22006319
25703557
|
TRBV12-3
|
CD1D
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
Reactome
|
18037897
26300885
15864273
14764708
20080535
15723809
7542404
21167756
22006319
25703557
|
TRAV19
|
CD1D
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
Reactome
|
18037897
26300885
15864273
14764708
20080535
15723809
7542404
21167756
22006319
25703557
|
TRAC
|
CD1D
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
Reactome
|
18037897
26300885
15864273
14764708
20080535
15723809
7542404
21167756
22006319
25703557
|
CD3G
|
CD1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
Reactome
|
18037897
26300885
15864273
14764708
20080535
15723809
7542404
21167756
22006319
25703557
|
TRAV8-4
|
CD1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
Reactome
|
18037897
26300885
15864273
14764708
20080535
15723809
7542404
21167756
22006319
25703557
|
TRAC
|
CD1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
Reactome
|
18037897
26300885
15864273
14764708
20080535
15723809
7542404
21167756
22006319
25703557
|
TRAV19
|
CD1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
Reactome
|
18037897
26300885
15864273
14764708
20080535
15723809
7542404
21167756
22006319
25703557
|
TRBC1
|
CD1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
Reactome
|
18037897
26300885
15864273
14764708
20080535
15723809
7542404
21167756
22006319
25703557
|
TRAV29DV5
|
CD1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
Reactome
|
18037897
26300885
15864273
14764708
20080535
15723809
7542404
21167756
22006319
25703557
|
TRBV7-9
|
CD1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
Reactome
|
18037897
26300885
15864273
14764708
20080535
15723809
7542404
21167756
22006319
25703557
|
TRBV12-3
|
CD1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
Reactome
|
18037897
26300885
15864273
14764708
20080535
15723809
7542404
21167756
22006319
25703557
|
TRAV8-4
|
CD1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
Reactome
|
18037897
26300885
15864273
14764708
20080535
15723809
7542404
21167756
22006319
25703557
|
TRAC
|
CD1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
Reactome
|
18037897
26300885
15864273
14764708
20080535
15723809
7542404
21167756
22006319
25703557
|
TRAV29DV5
|
CD1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
Reactome
|
18037897
26300885
15864273
14764708
20080535
15723809
7542404
21167756
22006319
25703557
|
TRBV12-3
|
CD1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
Reactome
|
18037897
26300885
15864273
14764708
20080535
15723809
7542404
21167756
22006319
25703557
|
TRBC1
|
CD1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
Reactome
|
18037897
26300885
15864273
14764708
20080535
15723809
7542404
21167756
22006319
25703557
|
TRBV7-9
|
CD1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
Reactome
|
18037897
26300885
15864273
14764708
20080535
15723809
7542404
21167756
22006319
25703557
|
TRAV19
|
CD1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
Reactome
|
18037897
26300885
15864273
14764708
20080535
15723809
7542404
21167756
22006319
25703557
|
CD1A
|
CD3G
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
Reactome
|
18037897
26300885
15864273
14764708
20080535
15723809
7542404
21167756
22006319
25703557
|
CD3G
|
CD1C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
Reactome
|
18037897
26300885
15864273
14764708
20080535
15723809
7542404
21167756
22006319
25703557
|
TRAC
|
CD1C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
Reactome
|
18037897
26300885
15864273
14764708
20080535
15723809
7542404
21167756
22006319
25703557
|
TRBV12-3
|
CD1C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
Reactome
|
18037897
26300885
15864273
14764708
20080535
15723809
7542404
21167756
22006319
25703557
|
TRBV7-9
|
CD1C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
Reactome
|
18037897
26300885
15864273
14764708
20080535
15723809
7542404
21167756
22006319
25703557
|
TRAV29DV5
|
CD1C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
Reactome
|
18037897
26300885
15864273
14764708
20080535
15723809
7542404
21167756
22006319
25703557
|
TRAV8-4
|
CD1C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
Reactome
|
18037897
26300885
15864273
14764708
20080535
15723809
7542404
21167756
22006319
25703557
|
TRAV19
|
CD1C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
Reactome
|
18037897
26300885
15864273
14764708
20080535
15723809
7542404
21167756
22006319
25703557
|
TRBC1
|
CD1C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
Reactome
|
18037897
26300885
15864273
14764708
20080535
15723809
7542404
21167756
22006319
25703557
|