Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list
Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins
Filter Graph:

0.5
Layout:
  🔂

Click a node or edge for more data...
Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
ABL1 CNTNAP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ABL1 C6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ABL1 CDC42 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10601328 19564926
ABL1 CAV1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20808760 1000457
ABL1 AIRE â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ABL1 NFASC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ABL1 MAP2K6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17893873
GRB2 ACTN4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 AP2M1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
MAPK1 AP2M1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10608864 10818153
APAF1 CASP3 â—¼   CLEAVAGE ✅ 2.0 0.8 intact 5214497 11550094
BAX APAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11709054
GRB2 BAD â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
IKBKB BAD â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 23332762
BCL2L1 BAK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
BCL2L1 BAK1 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
BBC3 BAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22492984 17289999
NR4A3 BAX â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 30455429
MAPK1 BCL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217079 15225643
MAPK1 BCL2 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 5217079 15225643
BCL2 MAPK8 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 15733859 5217553
NFKB1 BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11704864 11313951
FOS BCL2L1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16911523
BCL2L1 MAPK8 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 15733859 5217553
CASP3 BID â—¼   CLEAVAGE ✅ 2.0 0.8 intact 0707715105 18723680
FASLG BID â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15659383 25241761
CASP8 CASP3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18669646 0712034105
CASP9 CASP3 â—¼   CLEAVAGE ✅ 2.0 0.8 intact 0707715105 18723680
AKT3 CASP3 â—¼   CLEAVAGE ✅ 2.0 0.8 intact 17544405 5219985
CASP3 AKT1 â—¼   CLEAVAGE ✅ 2.0 0.8 intact 17544405 5219985
CASP3 CASP9 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 12011067 15573119
CASP3 AKT2 â—¼   CLEAVAGE ✅ 2.0 0.8 intact 17544405 5219985
CASP3 PRKCQ â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 9252332 9431985
RARA CASP9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16166294
CCR10 GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
NFASC GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
CD80 GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9694876 7737275
CD86 GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9694876 7737275
PIK3CA GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
GRB2 NCL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 ACTG1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 CBLB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 AIRE â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
GRB2 GAB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5212828 10913131
GRB2 CNTNAP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
GRB2 C6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
GRB2 ACTN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 H3C2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 ABL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
GRB2 PPP3CB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
MAPK3 GRB2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 7739560 8816480
TEC GRB2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 11406363 15214048
VAV1 GRB2 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
GRB2 CBLB â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
MAPK1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8994038
GRB2 ITK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10636929
MAP2K6 MAPK11 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8622669 7535770
MAP2K6 MAPK8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11460167 10882101
FOS MAPK1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 7588633 12134156
MAPK1 MAP2K3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 16709866
MAPK1 MAPK8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15778365
MAPK3 CASP8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219611 17290218
FOS MAPK3 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 7588633 12134156
MAPK3 GAB2 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 5217186 15356145
MAP3K14 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12049732 16691505
NFATC2 IL2RA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17463169 9763616
NFATC2 CD3E â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16219537 12374807
FOS NFATC2 â—¼   PROXIMITY 2.0 0.8 intact 18172215 0705181105
CD3G VAV3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8986718 16546099
SYK VAV3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8986718 16546099
VAV1 VAV3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9705280 11804587
CD247 VAV3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8986718 16546099
VAV3 ALK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17998938 6731818
RHOA VAV3 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 18589439 8990121
ITK VAV3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12186560 23109003
NFKB2 CDK6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18504428
CDK6 CCND3 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
CAV1 ACTB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17502619 0611416104
TSHR ACTB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
FOS BATF3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12087103
BATF3 IL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12087103 10878360
ACTG1 IKBKB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
ACTG1 NFKBIA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
ACTG1 MAP3K14 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
ATP6V1G1 ATP6V1E1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
C3 CD55 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 6238120 8786315
NFKBIA NFKB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
NOS1 NFKBIA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17910475
VAV1 SYK â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8986718 16546099
PIK3CA SYK â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15536084 11907067
PIK3CB SYK â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15536084 11907067
SYK B2M â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9830044 9396765
SYK MAPK11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12038794 8636072
SYK PIK3CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9720763 10592173
VAV1 CD247 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8986718 16546099
PIK3R2 CD247 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12869549 15536084
CD247 PIK3CA â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12869549 15536084
CD247 PIK3CB â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12869549 15536084
CD3G CD247 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
CD3E CD247 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
HLA-DRA CD247 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
CD3D CD247 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
HLA-DQA1 CD247 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
CD247 PRKCQ â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 16978534 12473184
PTPRC CD247 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 7526385
PRKCQ BCL10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219779 17363905
CD3G VAV1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8986718 16546099
RHOA VAV1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18511940 6743311
VAV1 TEC â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11328862 7651724
VAV1 CDC42 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18511940 6743311
RAC2 VAV1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 18589439 8990121
PIK3CA VAV1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11094073 9891995
IL4 JAK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12223527 23124025
IL2RA JAK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15178252 16477002
HMGA1 IFNG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15710911 7629508
PTEN CAV1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12176037 6731969
DNMT1 PTEN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19339266 21229291
CAV1 PTEN â—¼   COLOCALIZATION 2.0 0.8 intact 12176037 6731969
CDC42 PTEN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 16381926
PTEN AKT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 10644997
NR4A3 TGFB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12810687 17941092
MAPK8 FASLG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15659383 25241761
CASP8 NCL â—¼   COLOCALIZATION 2.0 0.8 intact 5219611 17290218
CASP8 IKBKB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11002417
CD80 PIK3CA â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12670391 8621607
NFKB1 CD80 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12860928 11359799
IL2RA IL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0607058103 17032757
NFKB2 MAP3K8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
AKT3 MAP3K8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12138205 23109003
MAP3K8 MAP2K3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17637696
FOS RHOA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10085083 15068801
RHOA NCL â—¼   COLOCALIZATION 2.0 0.8 intact 21281639 8086571
RHOA AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15884057 11748077
PIK3CB ANGPT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10521483 9632797
PIK3CA ANGPT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10521483 9632797
PIK3R2 ANGPT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10521483 9632797
CD86 PIK3CA â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12670391 8621607
HLA-DQA1 ZAP70 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8520027 9850860
HLA-DRA ZAP70 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8520027 9850860
CD3E ZAP70 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
HLA-DQA1 ZAP70 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
CD3D ZAP70 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
CD3G ZAP70 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
HLA-DRA ZAP70 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
CDC42 EIF2AK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7738010 5220554
CDC42 MAP2K3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11704645 14724572
PIK3CB B2M â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15536084 11907067
PIK3CA B2M â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15536084 11907067
PIK3R2 B2M â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15536084 11907067
GRAP2 CD28 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6731212 10820259
CD28 CBLB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12193687 23109003
CBLB PIK3CB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17635922 10514377
CBLB PIK3R3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17635922 10514377
CBLB PIK3CD â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17635922 10514377
CD4 HLA-DRA â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
CD4 CD3G â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
CD4 HLA-DQA1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
CD4 CD3D â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
CD4 CD3E â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
DNMT1 CD4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18586981 20223637
PRKCQ MALT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219779 17363905
HLA-DRA PRKCQ â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 16978534 12473184
HLA-DQA1 PRKCQ â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 16978534 12473184
CD3E PRKCQ â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 16978534 12473184
CD3G PRKCQ â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 16978534 12473184
CD3D PRKCQ â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 16978534 12473184
NR4A3 TEC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22739199 9177279
NFKB1 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18031796
MAPK8 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16306447
PIK3CA FOS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RARA FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19546303 9507016
FOS NFKB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20188076
NFKB1 CCND2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21790895
IKBKB NFKB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
IRAK1 IKBKB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18180283 11096118
IKBKB IRAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18180283 11096118
IKBKB EIF2AK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10848580 16600570
HLA-DRA CD3G â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
HLA-DRA CD3D â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
HLA-DRA CD3E â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
HLA-DRA HLA-DQA1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
HMGA1 HLA-DRA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9823775 7629508
NFKB2 CCND2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18504428
CCND3 CCNE1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16609025
NCL MAP3K14 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
NCL NFKB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CD3G PIK3CA â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12869549 15536084
PIK3CD PIK3CA â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9885561 10455108
PIK3CA PIK3CB â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9885561 10455108
PIK3CD PIK3CB â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9885561 10455108
MAP2K3 MAPK11 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8622669 7535770
HSPA6 MAP3K14 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
RARA HLA-DRB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20724538 10766818
CD3G PIK3CB â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12869549 15536084
HLA-DQA1 CD3D â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
CD3D CD3G â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
CD3D CD3E â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
HLA-DQA1 CD3E â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
CD3E CD3G â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
ATP6V1G2 ATP6V1E1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14667819 5216829
AIRE ICA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22447927
PIK3R2 CD3G â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12869549 15536084
HMGA1 CCNE1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 23229232 17877762
HLA-DQA1 CD3G â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
C6 C7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17900710 10696521
PTPRD LRRC4B â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20139422 19252495
HMGA1 H2BC12L â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
NLGN4X NRXN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20543817 18923512
CD55 C4A â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 6238120 8786315
CCL25 CCR9 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10229797 10640743
C8B C8G â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
ATP6V0D1 ATP6V1B2 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
ATP6V1B1 ATP6V1H â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
CAV1 RHOA â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 31871319 20460433 9647788
ATP6V0A2 ATP6V1E1 â—¼   PHYSICAL_INTERACTION 809.0 0.81 STRING 36370105
ATP6V0A2 ATP6V1B1 â—¼   PHYSICAL_INTERACTION 810.0 0.81 STRING 36370105
C8B C9 â—¼   PHYSICAL_INTERACTION 816.0 0.81 STRING 36370105
CD28 GRAP2 â—¼   PHYSICAL_INTERACTION 817.0 0.81 STRING 36370105
BAD BAX â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19427863 17274640
CAV3 CAV1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
AKT3 AKT1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CD22 PTPRC â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 10648410 10228003
ATP6V0A1 ATP6V0E1 â—¼   PHYSICAL_INTERACTION 819.0 0.82 STRING 36370105
BAD BCL2 â—¼   RELOCALIZATION ✅ - 0.82 0.82 Signor 15694340
ATP6V0B ATP6V1H â—¼   PHYSICAL_INTERACTION 823.0 0.82 STRING 36370105
AKT1 BAD â—¼   PHOSPHORYLATION ✅ - 0.82 0.82 Signor 9346240
RHOA MAPK8 â—¼   PHYSICAL_INTERACTION ✅ + 0.82 0.82 Signor 8824197
BCL2L1 APAF1 â—¼   PHYSICAL_INTERACTION ✅ - 0.82 0.82 Signor 9539746
GRB2 ZAP70 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 23267066 7629168
ACTB CAV1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 17502619 28734243
C1R C1QA â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 2372546 10878362
ATP6AP1 ATP6V0A2 â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
CD247 CD3D â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
CD3D CD3G â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
BCL10 IKBKB â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
ATP6V0A1 ATP6V1E1 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
AP2M1 CD22 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 16713569 12646615
ATP6V0D1 ATP6V1A â—¼   PHYSICAL_INTERACTION 839.0 0.84 STRING 36370105
ATP6V0D1 ATP6V1H â—¼   PHYSICAL_INTERACTION 839.0 0.84 STRING 36370105
CCNE1 CDK6 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 9716181 28628118 28205554
C1QC C1QB â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 21054788 16189514 12960167 28325905
TGFB2 TGFB1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 27684187 11483955 33961781 11157754
CBLB ZAP70 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 10074432 21453975 16189514 33848699
HLA-DRB1 HLA-DRA â—¼   PHYSICAL_INTERACTION ✅ 0.84 0.84 mint 5220278 7477400
ALK GRB2 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
APAF1 BCL2L1 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
IKBKB NFKB1 â—¼   PHOSPHORYLATION ✅ - 0.84 0.84 Signor 11158290
ATP6V1D ATP6V1G2 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
IKBKB PRKCQ â—¼   PHYSICAL_INTERACTION 848.0 0.84 STRING 36370105
ABL1 JAK1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 9774693 12130510
CASP9 CASP3 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 11242052 8900201 25241761 1067155 15941357 11230124 15507451 18723680 17437405
CD86 CD28 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 27708164 21931534 11021528 7513726
AKT2 AKT1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 28514442 12149249 9736715 12176337 11445557 33961781 14500673 11278835 11546794
C8A C8B â—¼   PHYSICAL_INTERACTION 849.0 0.85 STRING 36370105
C8A C8G â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
CD8A CD8B â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
AKT1 PTEN â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
BAK1 BID â—¼   PHYSICAL_INTERACTION 853.0 0.85 STRING 36370105
ATP6V0A2 ATP6V0C â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
ATP6AP1 ATP6V0D1 â—¼   PHYSICAL_INTERACTION 859.0 0.86 STRING 36370105
CASP8 BCL2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 16183855 11406564
ITK GRB2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 10636929 8985255
CARD11 BCL10 â—¼   PHYSICAL_INTERACTION ✅ 0.86 0.86 mint 7228517 19444310
AKT1 PTEN â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 12297295 19903340 12077256 28628118 20605778 28205554 10866658 20596030
IL2RA IL2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 17032757 16477002 1993646
RARA AKT1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 16417524 23693014
ATP6V0A2 ATP6V1F â—¼   PHYSICAL_INTERACTION 859.0 0.86 STRING 36370105
ATP6AP1 ATP6V1C1 â—¼   PHYSICAL_INTERACTION 862.0 0.86 STRING 36370105
ATP6V0D1 ATP6V1D â—¼   PHYSICAL_INTERACTION 869.0 0.87 STRING 36370105
CASP8 BID â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 9727492 15659383 9727491 12097160 11832478 12196516 11085743
CASP3 BID â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 10364179 11399776 18723680
CASP8 CASP3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 15254227 11832478 18669646 11437602 8962078
VAV1 ZAP70 â—¼   PHYSICAL_INTERACTION 869.0 0.87 STRING 36370105
BCL2 BCL2L1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
CASP3 CASP9 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
ATP6V0A2 ATP6V0D2 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
CASP8 FASLG â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
BBC3 BCL2 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
PIK3R2 PIK3R3 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
ATP6V0D1 ATP6V1F â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
CD28 GRB2 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
CARD11 PRKCQ â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
IKBKB MAP3K14 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
ATP6V0A1 ATP6V0D1 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
HLA-A KIR3DL2 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
ACTN1 ACTN4 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 22863883 22939629
JAK1 GRB2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 11527382 8536716
VAV3 RHOA â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 32203420 10523675
CD4 CXCR4 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 10816381 15660419 14592831
AKT1 PIK3CA â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
MAP3K8 NFKB1 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
CD3E ZAP70 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
ATP6V1B1 ATP6V1B2 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
ABL1 DOK1 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
ATP6V0C ATP6V0D1 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
AKT1 BAD â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
ABL1 GRB2 â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
MAPK1 MAPK3 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
CD3D CD3E â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
ABL1 ABL2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15735735 12569093 27229929
CD28 GRB2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 9694876 27927989 7737275 7584133 8576157 24475931
C1QB C1QA â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 14681455 21054788 12960167
ATP6V1E2 ATP6V1G1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
FOS NFATC2 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
ATP6V0A1 ATP6V1D â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
CD274 CD80 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
ATP6V0A1 ATP6V1A â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
BBC3 BCL2L1 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
GRB2 VAV1 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
CASP8 BID â—¼   CLEAVAGE ✅ + 0.89 0.89 Signor 9727492
NFKB2 NFKBIA â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
ABL1 GRB2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 23950177 16713569 17474147 14725908 9407116 9516488 8194526 19380743 19823681 7926767 16955467
MAPK3 BAD â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 19777442 10597268 12566304
MAPK1 BAD â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 8929531 10597268 12566304
BAX BID â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 25241761 15574335 20956295 23374347 17289999
AKT3 BAX â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 14766748 15642728 17525161
BBC3 BAX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15574335
ACTB BCL2L1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
CASP3 NFKBIA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9367996 29752472
NFKB2 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12808109 20420878 16990795
PIK3CD GRB2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11002419 10995764 10448070
PIK3CB GRB2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11002419 10995764 10448070
CDC42 GRB2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
VAV3 GRB2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 32296183 18654987 12577067 11094073 21706016 20936779
GRB2 CD22 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 10748054 11551923
KIR2DL2 GRB2 â—¼   DOWN_REGULATES ✅ - 3.0 0.9 ACSN 11513144 21339333 9605119
JAK1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8536716 11527382
RHOA MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10617617 9854026 12810709
MAP2K3 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8226933
RHOA MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10617617 9854026 12810709
CDK6 CCND2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16189514 16713569 28628118 10022865 28205554 11360184 30217970 33961781 23602568 11358847 9178893
VAV1 ITGB2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 0802621 19234221 7215309
DOK1 ITGB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 19118207 12606711
C1R C1QA â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 10904115 15388251 761607
C1QC C1QA â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 14681455 21054788 12960167 28325905
C1QA C2 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 6019133 12396008 10925294
C1QA C4A â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 15199963 14280442 12396008
CTSG C3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24315997 1861080
C1R C1QC â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 10904115 15388251 761607
C1QC C1S â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 10904115 15388251 761607
C1QC C2 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 6019133 12396008 10925294
C1QC C4A â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 15199963 14280442 12396008
C1R C1QB â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 10904115 15388251 761607
C1QB C1S â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 10904115 15388251 761607
C1QB C4A â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 15199963 14280442 12396008
C1QB C2 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 6019133 12396008 10925294
CD3G SYK â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 7517665 8657103 15161916
JAK1 SYK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10825200
CD247 SYK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9295038 7761456 7522230
SYK PIK3R2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15536084
FOS CD40LG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11160303
CD2 IL2 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 19398758 19494291 26794910
CD2 CD4 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 19398758 19494291 26794910
CD2 IFNG â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 19398758 19494291 26794910
IKBKB BCL10 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 19909372 16301747 16356855
MALT1 BCL10 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21157432 31774199 23690623 25748427 17948050 20551178 17189706 21513986 22658522 22267217 14695475 22528498 27070702 31961340 11262391 24130731 27071417 33329596 19444310 27113748 25548215 11090634 30279415 19279678 25569716 18806265 33961781 29953499 19118383 27777308
BCL10 AKT1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16280327 24462114 24412244
IKBKB CARD11 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 19909372 16301747 16356855
VAV1 CD80 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18295596 15886116 10849438
VAV1 CD86 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18295596 15886116 10849438
KIR2DL2 IFNG â—¼   DOWN_REGULATES ✅ - 3.0 0.9 ACSN 11513144 21339333 9605119
NFKB2 CCL5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12820969 12388374 11259372
CD28 CD80 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 2164219 7964482 21982860 1847722 7545666
FOS IL4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 7665092 10772943 9133600
HMGA1 IL4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 8284217 7559428 8986808
CD3E ZAP70 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 8906806 11855827 8366117 8647168 7761456
KIR3DL2 B2M â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15580655 11861603 11955593
CD8A B2M â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15136729 15534202 16551255
KIR2DL2 B2M â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15580655 11861603 11955593
CD8B B2M â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15136729 15534202 16551255
NFKB1 B2M â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12480693 2196446
GRAP2 CD28 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 24475931 27927989 10820259
CBLB PIK3CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11087752 17635922 10514377
TEC DOK1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11071635 11825908 10823839
PIK3CB GAB2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11002419 10995764 10448070
PIK3CA GAB2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11002419 10995764 10448070
PIK3CD GAB2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11002419 10995764 10448070
CADM3 CADM1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 12050160 16467305 17967169
NFKB1 MMP3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11376631 19275880
IKBKB NFKB2 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 10723127 17047224 27701768
HLA-DRA HLA-DQA1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 9312039 1956401 16618111
RARA CCND3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16189514 16713569 12482873
RAC2 PIK3CA â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 7744773 8645157 11803464
PIK3CA ALK â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11280786 11110708 18097461
C1S C1R â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 31749804 10092586 2387866 9477945 33961781 10878362 2372546 12788922 17996945
C1S C4A â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 15199963 14280442 12396008
C1R C2 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 6019133 12396008 10925294
C1R C4A â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 15199963 14280442 12396008
NFKB2 MAP3K14 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11239468 15140882 16303288
RARA TPO â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14725900
RARA MMP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15246741 10415749 1682056
RARA CCR9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23460729 23814022 21148038
PIK3CB ALK â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11280786 11110708 18097461
PIK3R2 PIK3CB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22402981 8596638 11733063
PIK3R2 ALK â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11280786 11110708 18097461
C5 C6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 1387399 2808363
C8A C9 â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
C8A C9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10346902 3624872 4063341
CCR10 CCL28 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 10781587 10725696 10725697
BAX BID â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
BCL2 BID â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
CBLB ZAP70 â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
ACTB ACTG1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
BAD BCL2 â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
C1QB C1QC â—¼   PHYSICAL_INTERACTION 907.0 0.9 STRING 36370105
ATP6V0B ATP6V1D â—¼   PHYSICAL_INTERACTION 908.0 0.9 STRING 36370105
ATP6V0B ATP6V1F â—¼   PHYSICAL_INTERACTION 908.0 0.9 STRING 36370105
BAX BCL2L1 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
ATP6V1C2 ATP6V1D â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
CCND1 CDK6 â—¼   PHYSICAL_INTERACTION 919.0 0.92 STRING 36370105
ZAP70 CD247 â—¼   PHYSICAL_INTERACTION ✅ 0.92 0.92 mint 7528772 6730352
ATP6V1B1 ATP6V1C1 â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
BCL2L1 BID â—¼   PHYSICAL_INTERACTION 921.0 0.92 STRING 36370105
ATP6AP1 ATP6V0C â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
ATP6V0A1 ATP6V0C â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
ATP6V0C ATP6V1B2 â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
ATP6V0C ATP6V1C1 â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
ATP6AP1 ATP6V1D â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
ATP6V0A2 ATP6V1D â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
ATP6AP1 ATP6V1A â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
ATP6AP1 ATP6V1B2 â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
ATP6V0A1 ATP6V1B2 â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
ATP6AP1 ATP6V0A1 â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
ATP6V0A1 ATP6V1F â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
ATP6V0A1 ATP6V1C1 â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
ATP6AP1 ATP6V1F â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
CD247 CD3E â—¼   PHYSICAL_INTERACTION 923.0 0.92 STRING 36370105
ATP6V0C ATP6V1F â—¼   PHYSICAL_INTERACTION 925.0 0.92 STRING 36370105
SYK VAV1 â—¼   PHOSPHORYLATION ✅ + 0.92 0.92 Signor 11331248
ATP6V0C ATP6V0D2 â—¼   PHYSICAL_INTERACTION 928.0 0.92 STRING 36370105
ATP6V1C2 ATP6V1F â—¼   PHYSICAL_INTERACTION 928.0 0.92 STRING 36370105
ATP6V1B2 ATP6V1H â—¼   PHYSICAL_INTERACTION 928.0 0.92 STRING 36370105
NFKB1 MAP3K8 â—¼   PHYSICAL_INTERACTION ✅ 0.93 0.93 mint 25609649
ATP6V0C ATP6V1G2 â—¼   PHYSICAL_INTERACTION 931.0 0.93 STRING 36370105
ATP6V0A1 ATP6V1G2 â—¼   PHYSICAL_INTERACTION 931.0 0.93 STRING 36370105
ATP6V1C2 ATP6V1E1 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
ATP6V0A1 ATP6V1B1 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
CD3E CD3G â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
BAD BCL2L1 â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
ATP6V0B ATP6V0C â—¼   PHYSICAL_INTERACTION 934.0 0.93 STRING 36370105
ATP6V1B1 ATP6V1E2 â—¼   PHYSICAL_INTERACTION 934.0 0.93 STRING 36370105
PIK3CB PIK3R3 â—¼   PHYSICAL_INTERACTION 934.0 0.93 STRING 36370105
ATP6V1B1 ATP6V1C2 â—¼   PHYSICAL_INTERACTION 935.0 0.93 STRING 36370105
B2M CD8A â—¼   PHYSICAL_INTERACTION 936.0 0.93 STRING 36370105
ATP6V0C ATP6V1H â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
ATP6V0C ATP6V1A â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
ATP6V1C2 ATP6V1E2 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
ATP6V0B ATP6V1A â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
PIK3CB PIK3R2 â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
CCND2 CDK6 â—¼   PHYSICAL_INTERACTION 939.0 0.94 STRING 36370105
MALT1 BCL10 â—¼   PHYSICAL_INTERACTION ✅ 0.94 0.94 mint 17948050 6177522
ATP6V1B1 ATP6V1G2 â—¼   PHYSICAL_INTERACTION 939.0 0.94 STRING 36370105
CD3G CD3E â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 20890284 9582308 2138083
ATP6V1B2 ATP6V1G1 â—¼   PHYSICAL_INTERACTION 940.0 0.94 STRING 36370105
ATP6V1C2 ATP6V1G1 â—¼   PHYSICAL_INTERACTION 940.0 0.94 STRING 36370105
ATP6V0C ATP6V1D â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
ATP6V0C ATP6V1E1 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
ATP6V1C1 ATP6V1D â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
ATP6V1C2 ATP6V1G2 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
ATP6V1B1 ATP6V1F â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
ATP6V1A ATP6V1G2 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
ATP6V1B2 ATP6V1C1 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
ATP6V1B2 ATP6V1G2 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
PIK3CA PIK3R3 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
ATP6V1C1 ATP6V1F â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
ATP6V1A ATP6V1C1 â—¼   PHYSICAL_INTERACTION 944.0 0.94 STRING 36370105
ATP6V1A ATP6V1F â—¼   PHYSICAL_INTERACTION 944.0 0.94 STRING 36370105
ATP6V1B1 ATP6V1G1 â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
CD3E SYK â—¼   PHYSICAL_INTERACTION 946.0 0.94 STRING 36370105
ATP6V1A ATP6V1B1 â—¼   PHYSICAL_INTERACTION 946.0 0.94 STRING 36370105
C6 C8G â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
C6 C8B â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
C6 C9 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
C6 C8A â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
C6 C7 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
ACTG1 ACTB â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 8153045 21516116
GAB2 GRAP2 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 28514442 32296183 12176364 11997510 33961781 26186194
ATP6V1E1 ATP6V1G2 â—¼   PHYSICAL_INTERACTION 950.0 0.95 STRING 36370105
ACTN1 ACTN4 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
ATP6V1B2 ATP6V1C2 â—¼   PHYSICAL_INTERACTION 953.0 0.95 STRING 36370105
ATP6V1C1 ATP6V1E1 â—¼   PHYSICAL_INTERACTION 955.0 0.95 STRING 36370105
CCND3 CDK6 â—¼   PHYSICAL_INTERACTION 957.0 0.95 STRING 36370105
C5 C8G â—¼   PHYSICAL_INTERACTION 958.0 0.95 STRING 36370105
CASP9 APAF1 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 5221774 9390557
AKT1 BAD â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 15998799 10358075 25241761 11500364 9381178 11994280 23085457 15722337 19667065 15784622
CBLB GRB2 â—¼   PHYSICAL_INTERACTION 959.0 0.96 STRING 36370105
ATP6V1A ATP6V1G1 â—¼   PHYSICAL_INTERACTION 960.0 0.96 STRING 36370105
C1QA C1QC â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
C5 C8A â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
C5 C9 â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
IKBKB NFKB1 â—¼   PHYSICAL_INTERACTION 963.0 0.96 STRING 36370105
ATP6V1D ATP6V1G1 â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
C1QA C1QB â—¼   PHYSICAL_INTERACTION 967.0 0.96 STRING 36370105
DOK1 ABL1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 9008161 22974441 10688886 11071635 9822717 10567556 19823681
CDK6 CCND1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 15232106 16713569 10022865 24855949 17517622 33854235 11739795 14681455 24953629 11360184 33961781 10580009 17420273 21654808 11160398 9178893 19075005
GAB2 GRB2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 25416956 31980649 21706016 10068651 16371368 10391903 32296183 15143164 10913131 19523899 19172738 11782427 19380743 11882361 9660791 16253990 33961781 20936779
CDK6 CCND3 â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 8153045 21516116
CDK6 CCND3 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 16189514 25416956 33854235 14681455 21516116 32296183 17517622 9716181 11360184 30217970 23602568 15232106 26264872 27107012 32707033 16782892 16713569 8114739 29997244 32814053 33961781 26186194
NFKBIA IKBKB â—¼   PHOSPHORYLATION ✅ 0.97 0.97 mint 8209688 16126728 506093200
NFKB1 NFKB2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 14743216 27609421 21988832 17962807 15169888 35140242 25609649 15660126
SYK VAV1 â—¼   PHYSICAL_INTERACTION 970.0 0.97 STRING 36370105
ATP6V1B1 ATP6V1E1 â—¼   PHYSICAL_INTERACTION 970.0 0.97 STRING 36370105
ATP6V1B1 ATP6V1D â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
C1R C1S â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
ATP6V1A ATP6V1C2 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
C5 C6 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
C5 C7 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
ATP6V1E1 ATP6V1G1 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
C5 C8B â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
GAB2 GRB2 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
ATP6V1A ATP6V1H â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
BCL2L1 BAD â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 11583631 5214629
ATP6V1E1 ATP6V1H â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
ATP6V1E1 ATP6V1F â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
BAX BCL2 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
BAK1 BCL2L1 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
ATP6V1B2 ATP6V1F â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
ATP6V1F ATP6V1H â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
ATP6V1D ATP6V1H â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
ATP6V1A ATP6V1B2 â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
ATP6V1B2 ATP6V1E1 â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
ATP6V1B2 ATP6V1D â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
ATP6V1D ATP6V1F â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
APAF1 CASP9 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
NFKB1 NFKBIA â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
PIK3CA PIK3R2 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
BAD BCL2 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 16697956 15694340 7834748 9388232 17446862 9463381 20603619 10611223 14681455 11483855 33961781 19168699 15990872 9305851 15849194
BAX BCL2 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 21778226 18981409 15899854 32064756 10620799 21199865 17289999 9194558 8358790 21671007 16642033 21458670 22262057 9388232 10716992 20865015 14980220 9111042 24141421 17097560 15231068 9463381 33961781 17525735 29749471 23479509 26004684
BBC3 BCL2 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 15694340 16697956 14681455 17289999 33961781 11463392 26431330
BID BCL2 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 16697956 15694340 19074266 11583631 9727491 9463381 15520201 14681455 17289999 18835031 12624108
CBLB GRB2 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 21900206 28514442 16189514 25416956 31980649 12577067 31467278 26264872 10022120 9614102 29997244 21706016 32814053 33961781 20936779 10086340 27107012
B2M HLA-A â—¼   PHYSICAL_INTERACTION 989.0 0.99 STRING 36370105
HLA-DRA HLA-DRB1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
ATP6V1A ATP6V1E1 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
ATP6V1A ATP6V1D â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
IKBKB NFKBIA â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
ATP6V1D ATP6V1E1 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
ABL1 CASP9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 22553782 24974292 29066624 15657060 20841568 28177918
ABL1 NFKBIA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 14757045 20841568 12167702
ABL1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 34.0 1.0 Omnipath 11726515 16713569 20841568 8596638 16955467 10592173 8647802 8194526 7926767 14725908 23950177 8112292 9407116 23181695 19380743 17474147 9516488 19823681
ABL1 CAV1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 18083107 17389395 11094059 19534553 8632005 12531427 27292265 24632723 11075810 12036959 15592455 20841568 15951569 20808760 16151024
ABL1 VAV1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 11790798 19234221 23325923
ABL1 DOK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 11071635 10567556 12777393 9008161 15148308 15592455 25043303 18768933
ABL1 HSPA1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20841568 17892306
ABL1 ABL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 12569093 15735735 20841568
HLA-DQA1 AP2M1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 8397411 10480952 9202021 15749704
HLA-DRA AP2M1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 8397411 10480952 9202021 15749704
CASP3 APAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 12874265 21827945 11550094
BCL2L1 APAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 10811864 9488720 12963020 9539746
HSPA1A APAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 10934467 16713569
APAF1 CASP9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 63.0 1.0 Omnipath 17145710 15829969 15024710 9390557 19494828 11113115 10617566 9539746 10364241 10722681 27476169 21060833 19118655 20829884 16977332 10329646 15210107 10393175 16352606 11242052 14555243 10376594 12773388 10206961 19337385 10428850 9488720 19788417 15262985 9922454 21827945 10749135 9651578 19698783 12792650 9837928 11227497
BCL2 BAD â—¼   PHYSICAL_INTERACTION 20.0 1.0 ACSN 10826997 10949026 11342610 11704864 12107820 12175651 12444011 12767520 16931767 17446862 19030972 19641503 21540285 22039431 23064052 23377657 23430059 23850759 8929532 9346240
BCL2 BAD â—¼   PROTEIN_INTERACTION 20.0 1.0 ACSN 10826997 10949026 11342610 11704864 12107820 12175651 12444011 12767520 16931767 17446862 19030972 19641503 21540285 22039431 23064052 23377657 23430059 23850759 8929532 9346240
AKT1 BAD â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 ACSN 10722653 10949026 11715018 11756412 11923280 15169778 15808505 16697215 17052453 17680028 18372248 18570873 18636226 20138985 20214616 20398329 20832730 9812896
PPP3CB BAD â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 10089876 11796223 14741051 15036616 17593948 18235236 19136967 19608982 2550447 7650486 9973469
PRKCQ BAD â—¼   ENZYMATIC_REACTION ✅ 13.0 1.0 ACSN 10652356 15214048 15536066 16606694 17544292 17548359 18784374 19201850 23077238 23433459 23474202 23886063 25960930
MAPK8 BAD â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 11983683 12189144 14673001 16166315 15526032 29795446 15907327 14967141 15725726 17555943
PPP3CB BAD â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 10195903 18235236 15036616 16648474 22820751 17662023 7593193 19136967 17593948 11796223 14741051 14627704 2550447 19608982
AKT3 BAD â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 26.0 1.0 Omnipath 9346240 11493700 20398329 21506126 9381178 20028971 12040186 21303971 15280015 20214616 10230394 10558990 8929531 10837486 11882383 10611223 23109003 12954615 22094462 10949026 15023346 17680028 18218901 17270021
AKT1 BAD â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 137.0 1.0 Omnipath 10880354 19052636 21506126 20028971 21303971 20214616 11994280 8929531 17570479 12832477 17555943 25241761 11715018 18636226 21998731 9812896 17680028 11500364 18385666 18707149 10201527 18218901 11983683 10490655 19030972 19667065 11756412 11020382 16931767 18372248 15808505 20138985 18046313 18669648 19121340 19703413 11714830 10949026 15972258 16341064 10358075 23085457 18220336 10516287 12897128 9580112 9651683 11923280 9346240 16697215 19690332 11493700 15452053 12040186 10826997 12175651 15722337 14737178 11882383 15226424 10521512 15023346 15784622 17052453 16044149 16403219 12444011 20166139 20398329 9381178 11544290 15037618 12767520 15280015 10230394 10558990 15998799 10082559 11577096 10837486 15169778 10611223 23109003 12954615 22094462 11438654 11312610 11254732 21540285 10383455 19664994 10722653 20832730 18570873 10926925 17270021
AKT2 BAD â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 27.0 1.0 Omnipath 9346240 11493700 20398329 21506126 9381178 15452053 20028971 12040186 21303971 15280015 20214616 10230394 10558990 8929531 10837486 11882383 10611223 12954615 22094462 10949026 11438654 17680028 10516287 18218901 17270021
BAD BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 33.0 1.0 Omnipath 9305851 17145710 11483855 16697956 9463381 15694340 15849194 20603619 15990872 11583631 8929531 7834748 9388232 17446862 19168699
BAD BCL2L1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 79.0 1.0 Omnipath 9305851 22705850 9389483 11483855 16697956 19667065 18628207 11907096 25416956 10620799 31467278 32814053 20837658 9388232 11077446 21988832 26871637 11206074 8929531 16189514 7834748 19427857 12115603 11494146 26186194 15694340 25241761 23109003 20603619 32296183 15705582 15131699 29997244 9372935 11583631 31515488 9824152
BCL2 BAK1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 ACSN 11704864 17446862 22039431 23064052 23377657 23430059 23850759 8929532
BCL2 BAK1 â—¼   PROTEIN_INTERACTION 8.0 1.0 ACSN 11704864 17446862 22039431 23064052 23377657 23430059 23850759 8929532
BID BAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 17145710 23782464 17289999 11175253 10950869 12624108 23604079 12242151
BCL2 BAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 17145710 9463381 14980220 11206074 17289999 26004684 11728179 20836993 19168699
BCL2L1 BAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 35.0 1.0 Omnipath 22705850 9463381 22516262 31467278 32814053 9020082 23680104 34098062 18178565 15901672 16189514 17446862 20836993 23055042 19060904 17289999 32296183 10085290 14596824 15292519 29997244 31515488 11175750 9027312
BAK1 BAX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 15901672 11571294 16189514 16439990
BCL2 BAX â—¼   PHYSICAL_INTERACTION 15.0 1.0 ACSN 11704864 16227588 17446862 17891140 20709625 21641962 22039431 23064052 23377657 23430059 23850759 7644501 8358790 8929532 9872359
BCL2 BAX â—¼   PROTEIN_INTERACTION 15.0 1.0 ACSN 11704864 16227588 17446862 17891140 20709625 21641962 22039431 23064052 23377657 23430059 23850759 7644501 8358790 8929532 9872359
NFKB1 BAX â—¼   DOWN_REGULATES ✅ - 6.0 1.0 ACSN 12676992 15613549 21725609 23178297 23572150 7834749
BID BAX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 20956295 17289999 25241761 19968986 15574335 10629050 19062087 10949027 12242151 23374347 14730312 17520191 8918887
MAPK8 BAX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15525785 18471544 16709574
AKT1 BAX â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 26763134 14766748 15642728 17525161
BCL2L1 BAX â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 59.0 1.0 Omnipath 22705850 18981409 21458670 28202514 11283018 17525735 29749471 21567405 9388232 18547146 19074440 16151013 21199865 18178565 26496610 16189514 15486085 26186194 17289999 9111042 12419244 25241761 14963330 12853473 9742125 9153240 19427863 21852238 14766748 21671007 15131699 9670005 8596636 24814347 9824152 9027312
BCL2 BAX â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 60.0 1.0 Omnipath 17145710 22705850 18981409 9463381 21458670 17097560 17525735 8358790 10620799 26004684 29749471 9388232 21199865 17525161 22262057 21778226 15486085 17289999 9111042 12419244 9194558 15231068 10716992 8183370 14980220 9115213 21671007 16642033 23479509 10677502
BCL2 BBC3 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 11463391 11463392 11704864 17446862 22039431 23064052 23377657 23430059 23850759 8929532
BCL2 BBC3 â—¼   PROTEIN_INTERACTION 10.0 1.0 ACSN 11463391 11463392 11704864 17446862 22039431 23064052 23377657 23430059 23850759 8929532
BBC3 BCL2L1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 17145710 16697956 15694340 19074266 28202514 15574335
BBC3 BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 17145710 16697956 15694340 11463392
NFKB1 BCL2 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 11313951 11704864 21725609 23178297 23572150
BCL2 GRB2 â—¼   ENZYMATIC_REACTION ✅ 20.0 1.0 ACSN 11463391 11463392 11532940 11704864 12566895 12667443 14764585 15516985 17446862 19289794 19565474 22039431 23064052 23377657 23430059 23850759 24027568 8929532 9069260 9872359
NFKB1 BCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 16254192 11567031 17673602 18031796 12835724 15120608 20332461 14978135 20446017 18566231 19259124 14739605 21503108 20103608 17098279 18158998 12032828 19233129 16022909 18761399 18987666 15934930 21224428 16453001
CASP3 BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 10409669 9395403 20139069 11948397
MAPK3 BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 9115213 10669763 9735392 11323415 21785723 9738012 10677502 23272207 25826088
BCL2L1 BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18835031 14980220 26186194 11583631
AKT1 BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 21303971 11882383 17680028 20214616 22094462 20398329 21506126 20028971 12040186 18218901
MAPK1 BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 29.0 1.0 Omnipath 9115213 10567572 12039864 10669763 15225643 11323415 21785723 9738012 11337027 10677502 23272207
MAPK8 BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 45.0 1.0 Omnipath 12421819 26609913 17097560 16738310 21726807 10567572 21993018 29950132 20919655 22848813 15225643 19029119 9738012 18570871 9115213 12039864 11323415 15733859 18471544 15703383 23329792 10677502
AKT3 BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 21303971 11882383 17680028 20214616 22094462 20398329 21506126 20028971 12040186 18218901
BCL2 CASP8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 16183855 11406564
BCL2 BID â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 18835031 17145710 9463381 16697956 17289999 19074266 12624108 11583631 9727491 15520201 8918887
NFKB1 BCL2L1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 10925251 17673602 12176906 11992002 14978135 15231833 14739605 10585435 20066113 16904634 9439816 18222423 10733571 15756023 15986355 12226754 15856023 16453001 11756417 18223231
MAPK8 BCL2L1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 10617621 25241761 15733859 12633850 18471544
AKT1 BCL2L1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 20138985 15169778 9812896 17680028 11756412 11923280 20214616 16697215 10949026 10722653 20832730 18570873 18372248 11715018 20398329 17052453 18636226 15808505
NFKB1 BCL2L1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10428780 19211554 10435632 10428030 11756417
BID BCL2L1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 9727492 19074440 16697956 15694340 17289999 25241761 22464442 14963330 16189514 27159560 24814347 15574335
BCL2L1 CASP9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 16189514 25241761 9539746
MAPK8 BID â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 18594987 25326334 25077544 27374471
CASP3 BID â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 9727492 10364179 10805722 11832478 11085742 11085743
CASP8 BID â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 9727492 10364179 10805722 11832478 12196516 18458084 9727491 11085742 11085743 12097160 9873064
CASP8 CASP3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 15755874 17179148 9501089 9950028 18669646 23308069 10988287 18458084 16964285 9885230 9765224 11437602 15014070 21295084 8962078 9208847
CASP9 CASP3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 37.0 1.0 Omnipath 10708865 9390557 10508159 11230124 18723680 15657060 16977332 15507451 1067155 9708736 25241761 8900201 11242052 9765224 17437405 19788417 9812896 12620238 15941357 12181739 19465923 12792650 15725726
CASP3 IKBKB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 9367996 11741536
CASP3 NFATC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 16455648 17613518 19900451 9390557
CASP3 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 17544405 12124386 10579725
AKT1 CASP9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 42.0 1.0 Omnipath 11756412 11923280 16697215 20398329 18372248 15004527 15808505 20138985 20214616 15703181 17570479 28177918 18840507 15169778 11714830 10949026 16341064 11715018 18636226 10529400 9812896 17680028 19440551 10722653 20832730 18570873 17052453
AKT2 CASP9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 9812896 15004527
AKT3 CASP9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 9812896
MAPK3 CASP9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 38.0 1.0 Omnipath 15547943 20080742 29416675 12040186 15173823 12697810 11940578 19081073 19586613 16227978 12738796 16039586 17466630 17255949 18669648 15187187 19016842 19541618 19091303 19565474 17052211 18039929 18775330 10601235 12792650 11431469
MAPK1 CASP9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 44.0 1.0 Omnipath 15547943 20080742 12040186 18083711 15173823 12697810 11940578 19081073 19586613 16227978 12738796 16039586 17466630 17255949 18669648 16888006 15187187 19016842 19541618 19091303 19565474 17052211 18039929 18775330 10601235 12792650 11431469
NFKB1 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 17673602 10464245 18566231 18341653 11861406 20103608 12894581 17098279 22306268 10409765 19766095 15756023 17407600 18184402 17944672 17008396 15856023 20538607 19263436 16453001
FOS CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 19847806 22550166 15994929 21474819 23157741 15282324 11287611 20188076 9710644 14508521
CCND1 CDK6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 19075005 17517622 9178893 11739795 24855949 15232106 16713569 11360184 10580009 11160398
SYK GRB2 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 12456653 9341187 9705962 19372136 11071869 11449366 11909947 9697839 21822214
GRB2 SYK â—¼   PHYSICAL_INTERACTION 71.0 1.0 ACSN 10022831 10086337 10358164 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11907067 11960372 12175651 12393695 12524384 12629515 12640133 13678960 14568985 15099563 15111329 15501236 15520864 15536084 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17101731 17496910 17673906 17883421 19414323 19449109 19909365 20150200015 21149606 21372296 21378271 21910624 22064427 22461508 23390297 23609447 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8189062 8226994 8551221 8837607 9000133 9157999 9295024 9314552 9396765 9570538 9632805 9753319 9763615
GRB2 ANGPT1 â—¼   PHYSICAL_INTERACTION 24.0 1.0 ACSN 10086337 10567412 10811803 10849428 10982827 11283723 11447289 11449354 11777939 12175651 12393695 12640133 15520864 15567848 15574420 16076871 16582911 16887996 17496910 17673906 19223473 19449109 26552706 8551221
GRB2 CD28 â—¼   PHYSICAL_INTERACTION 23.0 1.0 ACSN 10086337 10209041 10567412 10811803 10982827 11447289 11777939 12175651 12640133 1313950 15197224 15567848 15574420 16582911 16887996 17496910 17673906 19449109 22437870 26552706 7523569 8551221 9359474
GRB2 SYK â—¼   SHARES_COMPLEX 71.0 1.0 ACSN 10022831 10086337 10358164 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11907067 11960372 12175651 12393695 12524384 12629515 12640133 13678960 14568985 15099563 15111329 15501236 15520864 15536084 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17101731 17496910 17673906 17883421 19414323 19449109 19909365 20150200015 21149606 21372296 21378271 21910624 22064427 22461508 23390297 23609447 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8189062 8226994 8551221 8837607 9000133 9157999 9295024 9314552 9396765 9570538 9632805 9753319 9763615
GRB2 CD28 â—¼   SHARES_COMPLEX 23.0 1.0 ACSN 10086337 10209041 10567412 10811803 10982827 11447289 11777939 12175651 12640133 1313950 15197224 15567848 15574420 16582911 16887996 17496910 17673906 19449109 22437870 26552706 7523569 8551221 9359474
GRB2 ANGPT1 â—¼   SHARES_COMPLEX 24.0 1.0 ACSN 10086337 10567412 10811803 10849428 10982827 11283723 11447289 11449354 11777939 12175651 12393695 12640133 15520864 15567848 15574420 16076871 16582911 16887996 17496910 17673906 19223473 19449109 26552706 8551221
ITK GRB2 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 11406363 12186560 15661896 25137453
FOS GRB2 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 11274345 12738796 15067049 16393692 16394015 18039929 19667062 21385848 22634314 23430059 9064320
CD226 GRB2 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 10591186 12913096 14676297 19029380 22285893 24337740 24658051 26552706 26840537 28893624 8673704
CD247 GRB2 â—¼   ENZYMATIC_REACTION ✅ 24.0 1.0 ACSN 10562324 10925299 11353765 11438547 11875494 12415267 12731048 12811837 15735648 16713974 17371980 20435894 20814939 21059766 23414611 23508573 23620508 23886063 24378531 7600293 8478617 8642247 9625766 9738502
ZAP70 GRB2 â—¼   ENZYMATIC_REACTION ✅ 24.0 1.0 ACSN 10562324 10925299 11353765 11438547 11875494 12415267 12731048 12811837 15735648 16713974 17371980 20435894 20814939 21059766 23414611 23508573 23620508 23886063 24378531 7600293 8478617 8642247 9625766 9738502
GRB2 SYK â—¼   ENZYMATIC_REACTION ✅ 71.0 1.0 ACSN 10022831 10086337 10358164 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11907067 11960372 12175651 12393695 12524384 12629515 12640133 13678960 14568985 15099563 15111329 15501236 15520864 15536084 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17101731 17496910 17673906 17883421 19414323 19449109 19909365 20150200015 21149606 21372296 21378271 21910624 22064427 22461508 23390297 23609447 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8189062 8226994 8551221 8837607 9000133 9157999 9295024 9314552 9396765 9570538 9632805 9753319 9763615
GRB2 GAB2 â—¼   ENZYMATIC_REACTION ✅ 25.0 1.0 ACSN 10086337 10358164 10567412 10811803 10849428 10982827 11447289 11449354 11777939 12175651 12393695 12640133 15567848 15574420 16076871 16212621 16582911 16887996 17496910 17673906 19449109 19909365 26552706 8551221 9763606
GRB2 VAV1 â—¼   ENZYMATIC_REACTION ✅ 57.0 1.0 ACSN 10077632 10086337 10426994 10567412 10646608 10679059 10714681 10811803 10849438 10898494 10982827 11080163 11447289 11526404 11698448 11754814 11777939 11777960 11907067 11994416 12094222 12165654 12175651 12186560 12616499 12626562 12640133 12740575 12885870 12917349 14764585 15169881 15536084 15567848 15574420 16339513 16582911 16713974 16887996 17070508 17100878 17496910 17673906 18490724 19449109 19909365 20189481 22513334 22786724 22952938 25355530 25539813 26552706 8189062 8226994 8551221 9438848
GRB2 ANGPT1 â—¼   ENZYMATIC_REACTION ✅ 24.0 1.0 ACSN 10086337 10567412 10811803 10849428 10982827 11283723 11447289 11449354 11777939 12175651 12393695 12640133 15520864 15567848 15574420 16076871 16582911 16887996 17496910 17673906 19223473 19449109 26552706 8551221
GRB2 MAP2K6 â—¼   ENZYMATIC_REACTION ✅ 34.0 1.0 ACSN 10086337 10567412 10811803 10982827 11274345 11447289 11777939 12040186 12175651 12419216 12640133 12738796 12782630 14585353 15567848 15574420 15863030 16102570 16227978 16488589 16582911 16887996 17496910 17673906 18855897 19449109 19568798 19615955 21102635 21614932 24027568 26552706 7510700 8551221
PTEN GRB2 â—¼   REGULATES ✅ 15.0 1.0 ACSN 10648629 10753747 11747822 12040186 15584861 15721744 16288286 16982858 17218262 19847259 22179046 22465479 23732914 24254977 25364523
PTEN GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 16288286 10648629 17218262 12040186 15584861
CD28 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 18829987 8576157 9694876 24098653 27927989 21487479 7737275
CBLB GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 31.0 1.0 Omnipath 10022120 25416956 21706016 31467278 32814053 9614102 17635922 11375397 8626404 16189514 21900206 20936779 27107012 12577067 10514377 19531499 10086340 29997244
SYK GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11964172 16189514 22267732 10747947
VAV1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 32.0 1.0 Omnipath 8900182 10207103 9013873 15558030 7651724 7809090 8621483 29997244 18692475 7478592 16713569 11406576 9209406 16339550
GRB2 GAB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 37.0 1.0 Omnipath 17145710 16371368 25416956 21706016 15143164 10391903 19172738 10913131 11027663 9973481 10973965 20936779 10068651 11882361 32296183 16199887 24737791 15010462 19523899 16253990 19380743 31515488 11782427
IRAK1 MAP2K6 â—¼   ENZYMATIC_REACTION ✅ 19.0 1.0 ACSN 11274345 12620219 12738796 14660645 15125833 16252010 16878026 17704786 17948050 18264787 18758450 18855897 18922473 18977329 19161412 21614932 23070005 23681101 23811849
MAP2K6 MAPK11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 18291705 23331499 9362518 11242034 8622669 9430721 21614932 12738796 11274345 11727828 9790884 18855897 8621675
MAP2K6 MAPK13 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 23331499 11242034 8663074 10201954 21614932 12738796 11274345 9218798 9790884 18855897
VAV1 MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 23331499 8900182 9013873
MAP3K8 MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 1712480 9166761 1378617 15972258 91184134 15935618 15592455 16094384 11971971 16153436
MAPK13 MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12738796 18039929 11274345 15187187
MAPK1 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12975377 23602568 16424009 19058874 23397142 21707490
MAPK1 EIF2AK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17404396 9528799
MAPK1 GAB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 12008033 15356145
MAPK1 CASP8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 24342355 17290218
MAPK1 FOS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 49.0 1.0 Omnipath 12134156 20506250 15547943 8248197 7816602 15084594 12697810 8226933 20068231 18452278 12738796 16393692 17255949 17439715 15187187 19541618 23109003 19565474 17722974 17052211 7588633 8545107 16055710 8388392 18039929 12972619 18775330 21098038 9604935 11274345
MAPK11 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12738796 18039929 11274345 15187187
MAPK13 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 12738796 18039929 11274345 15187187
MAPK3 FOS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 41.0 1.0 Omnipath 17018293 12134156 20506250 15547943 7816602 15084594 12697810 8226933 12738796 16393692 17255949 17439715 15187187 19541618 23109003 19565474 17722974 17052211 7588633 8545107 16055710 8388392 18039929 12972619 18775330 26725323 21098038 9604935 11274345
MAPK3 GAB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 12008033 15356145
MAPK3 CASP8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 24342355 17290218 26036637 29233910 24484936 20937773
PPP3CB NFATC2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 8576111 8631904 10860980 9727000 8799126
NFATC2 CD40LG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17237447 18719603
NFATC2 IL4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 29.0 1.0 Omnipath 11781715 15684054 11687571 22226971 23612709 19915002 9916709 7989759 12218118 9430230 15048722 8524816 10069428 11956291 10772943 10894164 12355451 12594266 17645498 8668213 25037220 21799768 18962896 9845517 9133600 8284217 9310836 18217957 15539155
NFATC2 IL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 15180435 20557936 8576111 8014029 8397339 7706710 21458306 21832163 8577772 17513763 16873067 8631809 11956291 12560487 17237447 24561192 18097033 7565732 8668213 7982959 21799768 8441422 9047239 8098881 1712901
NFATC2 IFNG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 23616576 18962896 15684054 12836278 22123848 11520798 12842891 18217957 22427656 22844476 10894164 21624129 16237086
NFATC2 CD4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 21799768 10692237 17463169 16880206 16219537 9916709 10799559
MAPK8 NFATC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 15743762 14517246 16648474 10978313 17570479 11274345
PPP3CB NFATC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 9660947 11062529 12594826 18676376 8631904 11030334
CD247 VAV3 â—¼   ENZYMATIC_REACTION ✅ 24.0 1.0 ACSN 10562324 10925299 11353765 11438547 11875494 12415267 12731048 12811837 15735648 16713974 17371980 20435894 20814939 21059766 23414611 23508573 23620508 23886063 24378531 7600293 8478617 8642247 9625766 9738502
ZAP70 VAV3 â—¼   ENZYMATIC_REACTION ✅ 24.0 1.0 ACSN 10562324 10925299 11353765 11438547 11875494 12415267 12731048 12811837 15735648 16713974 17371980 20435894 20814939 21059766 23414611 23508573 23620508 23886063 24378531 7600293 8478617 8642247 9625766 9738502
VAV3 RHOA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10523675 10592173 32203420
CCND3 CDK6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 17517622 8114739 26186194 27107012 23602568 10477583 16782892 21516116 25416956 29997244 31515488 32814053 15232106 32296183 11360184 16713569 9716181
CCND2 CDK6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10477583 17517622 16713569
FOS CCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 18024959 18443042 14752027 8063765 12667961 17424890 7602115 9558097 16206198 19404962
NFKB1 CCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 32.0 1.0 Omnipath 10644332 22189654 20038977 11512674 8630731 12488502 12540607 11716760 8617886 12218154 14631383 16325549 10744656 10530453 11006087 16040075 10987310 16206198 9388261 10614622 16818736 10636866 10469356 17507908 12647268 16764699 25108845 20200316 15950427 20579762 11949945
CCL2 CCR10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 9364936 10706668
NFKB1 CXCL1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8530498 7479086 15958549 10530453 16040075 11112786
ACTB RHOA â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 12805219 18001770 12732141 12429848 18923426
ACTB CDC42 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 24914801 15507212 16439214 22608513
C3 ITGB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 4062888 26293614
RHOA ACTG1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 12805219 18001770 12732141 12429848 18923426
CDC42 ACTG1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 24914801 15507212 16439214 22608513
NFKB1 CCL3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11716760 17707233 16982926 11342414
C9 C8G â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 9038722 16999828 7691959 17505110 16079145
IFNA6 IFNAR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 21856167
NFKB1 NFKBIA â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 1829648 21725609 23178297 23572150 8096091
IKBKB NFKBIA â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 9315679 9914500 9721103 10593898 9135156
NFKB1 NFKBIA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 17876798 15499023 17709515 7775482 11744993 10454561 11060311 12885753 9250151
NFKB1 NFKBIA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 61.0 1.0 Omnipath 17145710 25609649 7862124 1340770 16210649 16970925 21719482 9738011 9865693 10497169 8657102 9572494 9315679 21988832 8887676 10329681 1829648 14743216 17003112 11313474 20558726 26496610 7867065 7891711 10837071 7831327 15836773 26186194 11571291 15214841 17561400 16846590 9566883 8096091 15371334 7479976 11020244 9426183 16493424 15145317 8631829 20237821 20980497 16513645 9597130 7479848 7739549 7628694 10655476
EIF2AK2 NFKBIA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 24.0 1.0 Omnipath 9721103 16007147 12138192 10723127 7796813 12403772 8657102 10398585 8601309 9214631
SYK NFKBIA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 21674813 21459462 19014652 12711606 24101387
IKBKB NFKBIA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 164.0 1.0 Omnipath 18593939 17145710 18375836 11087742 16793322 11527961 28086098 21232017 12429743 21423167 17693123 21399639 15836773 16177806 9721103 29139553 9271416 17561400 11923072 10889159 17706453 10723801 12791687 11858955 22037600 16365431 10421793 25133483 10398585 9346484 9346241 11158290 18539148 23328071 15574499 21765415 16818647 8657102 18202307 16737960 9315679 21490922 9252186 20001801 15919917 16495515 11368781 16291755 24386391 14743216 25759022 10329646 10882136 16153868 10195894 14751757 18981174 10807933 16007147 7796813 9632633 15856023 17965022 25753787 10783893 10602462 27682876 16965765 15084594 19196987 17322026 12138192 10723127 15210742 16319058 15217903 15218526 7878466 9914500 17367806 9520446 15214841 16846590 12514169 18657515 12403772 10527519 15145317 16888014 16493424 17047224 9135156 15024091 16023083 10593898 14636585 22579987 9214631 24911653 7862124 10320352 16970925 23707515 9346485 12949498 17363905 12486103 9891086 8601309 10880512 7739562 16286467 23109003 9689078 25595906 15371334 16285893 11356195 29145629 23970940 10085062 11815618 17468758 17615396 24586253 17072322
CD3G SYK â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 8226994 18818202 8862523 8340414 7522622 7530449 9314552
CD247 SYK â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 8226994 18818202 8862523 8340414 7522622 7530449 9314552
CD247 SYK â—¼   ENZYMATIC_REACTION ✅ 21.0 1.0 ACSN 10358164 10562324 11353765 11449354 12393695 12731048 15081523 15099567 18768831 20814939 21059766 2139103 23414611 24445665 7523143 8344348 8478617 8551221 9603467 9625766 9738502
VAV1 SYK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 8900182 7518558 23331499 12573241 8629002 23180781 11331248 11262396 10592173 16189514 10092764 8630736 8986718 29145629 9151714 16546099 8809042 24243840
CBLB SYK â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 12771181 16189514 27428901 10022120
SYK GAB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11895767 16371368 18950707
CD40LG MAP3K14 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 19426221 12374738 24298274 9718306
CD40LG CD86 â—¼   ENZYMATIC_REACTION ✅ 16.0 1.0 ACSN 11207245 11581322 11698286 11964292 14764699 15034038 15197224 17200410 17317815 17371980 17513775 23002440 23125331 7523569 8760829 9359474
CD40LG CD80 â—¼   ENZYMATIC_REACTION ✅ 16.0 1.0 ACSN 11207245 11581322 11698286 11964292 14764699 15034038 15197224 17200410 17317815 17371980 17513775 23002440 23125331 7523569 8760829 9359474
CD40LG IL2 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 11581322 15034038 17200410 17371980 23125331 8760829
NFKB1 CD40LG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11751888 11529914 21243522 11160303
HLA-DQA1 CD247 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
CD4 CD247 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
HLA-DRA CD247 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
CD247 ZAP70 â—¼   PHYSICAL_INTERACTION 36.0 1.0 ACSN 10358164 10562324 10925299 11353765 11438547 11449354 11875494 12393695 12415267 12731048 12811837 15081523 15099567 15735648 16713974 17371980 18768831 20435894 20814939 21059766 2139103 23414611 23508573 23620508 23886063 24378531 24445665 7523143 7600293 8344348 8478617 8551221 8642247 9603467 9625766 9738502
CD247 B2M â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 18037897 26300885 15864273 14764708 20080535 15723809 7542404 21167756 22006319 25703557
CD247 ZAP70 â—¼   SHARES_COMPLEX 36.0 1.0 ACSN 10358164 10562324 10925299 11353765 11438547 11449354 11875494 12393695 12415267 12731048 12811837 15081523 15099567 15735648 16713974 17371980 18768831 20435894 20814939 21059766 2139103 23414611 23508573 23620508 23886063 24378531 24445665 7523143 7600293 8344348 8478617 8551221 8642247 9603467 9625766 9738502
B2M CD247 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 10358761 10559964 11154916 11509172 11717192 14508489 16181333 22076556 22790179 24457417 8642276
CD4 CD247 â—¼   ENZYMATIC_REACTION ✅ 16.0 1.0 ACSN 10398592 10652356 12731048 12740575 17544292 19290918 20814939 21127503 22513334 23620508 3263576 8478617 8986721 9438848 9738502 9751747
CD247 GAB2 â—¼   ENZYMATIC_REACTION ✅ 31.0 1.0 ACSN 10358138 10562324 10849428 10982827 11353765 11447289 11572860 12138178 12415267 12640133 12707331 12731048 15240681 15699106 15713798 15735648 16212621 17371980 19833085 19909365 20814939 21059766 23414611 23620508 23886063 7600293 8478617 8642247 9625766 9738502 9751747
CD247 ZAP70 â—¼   ENZYMATIC_REACTION ✅ 36.0 1.0 ACSN 10358164 10562324 10925299 11353765 11438547 11449354 11875494 12393695 12415267 12731048 12811837 15081523 15099567 15735648 16713974 17371980 18768831 20435894 20814939 21059766 2139103 23414611 23508573 23620508 23886063 24378531 24445665 7523143 7600293 8344348 8478617 8551221 8642247 9603467 9625766 9738502
CD247 IL2 â—¼   ENZYMATIC_REACTION ✅ 12.0 1.0 ACSN 10562324 11062502 11353765 11385609 12731048 15536084 20814939 21059766 23414611 8478617 9625766 9738502
CD247 PTPRC â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 12414720 19290918 23620508 23886063 25312647
PTPRC CD247 â—¼   DEPHOSPHORYLATION ✅ 5.0 1.0 Reactome 20346773 23580664 11827988 21543337 2530588
CD247 ZAP70 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 74.0 1.0 Omnipath 11449354 10752619 8906806 18768831 2139103 8551221 23886063 9185620 12415267 10358158 10704231 8648092 7528772 7737297 11875494 15832366 15081523 24445665 9603467 17371980 21957439 8344348 7600293 7509083 7523143 15099567 10925299 9625766 8642247 9036949 8901551 16189514 21059766 9738502 12393695 24378531 20814939 23109003 9295038 8366117 11438547 26390156 23414611 23620508 8478617 20435894 7761456 15268851 16713974 26192618 12731048 10562324 20637659 7522230 12811837 11353765 23508573 10358164 15735648
BCL10 CARD11 â—¼   PHYSICAL_INTERACTION 22.0 1.0 ACSN 11280761 11356195 11460167 12356734 14660645 16809782 16818229 17052756 17301840 17363905 17462996 17948050 18264101 18264787 20685844 21133840 21199863 21232017 21873235 24560716 24699077 24958845
BCL10 MALT1 â—¼   PHYSICAL_INTERACTION 22.0 1.0 ACSN 11280761 11356195 11460167 12356734 14660645 16809782 16818229 17052756 17301840 17363905 17462996 17948050 18264101 18264787 20685844 21133840 21199863 21232017 21873235 24560716 24699077 24958845
BCL10 MALT1 â—¼   SHARES_COMPLEX 22.0 1.0 ACSN 11280761 11356195 11460167 12356734 14660645 16809782 16818229 17052756 17301840 17363905 17462996 17948050 18264101 18264787 20685844 21133840 21199863 21232017 21873235 24560716 24699077 24958845
BCL10 CARD11 â—¼   SHARES_COMPLEX 22.0 1.0 ACSN 11280761 11356195 11460167 12356734 14660645 16809782 16818229 17052756 17301840 17363905 17462996 17948050 18264101 18264787 20685844 21133840 21199863 21232017 21873235 24560716 24699077 24958845
CARD11 MALT1 â—¼   PHYSICAL_INTERACTION 22.0 1.0 ACSN 11280761 11356195 11460167 12356734 14660645 16809782 16818229 17052756 17301840 17363905 17462996 17948050 18264101 18264787 20685844 21133840 21199863 21232017 21873235 24560716 24699077 24958845
CARD11 MALT1 â—¼   SHARES_COMPLEX 22.0 1.0 ACSN 11280761 11356195 11460167 12356734 14660645 16809782 16818229 17052756 17301840 17363905 17462996 17948050 18264101 18264787 20685844 21133840 21199863 21232017 21873235 24560716 24699077 24958845
PRKCQ CARD11 â—¼   ENZYMATIC_REACTION ✅ 13.0 1.0 ACSN 10652356 15214048 15536066 16606694 17544292 17548359 18784374 19201850 23077238 23433459 23474202 23886063 25960930
PRKCQ CARD11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 16356856 19706536 26884335 19118383 21157432 15520247 23109003 15125833 16356855 14673152 23474202
CARD11 MALT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 20685844 17948050 15122200 19118383
PIK3CD VAV1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 7691807 7687539 7687428 15187135 10706702 7528218
GRAP2 VAV1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11007481 8986718 10395673 9099726
CD4 VAV1 â—¼   ENZYMATIC_REACTION ✅ 16.0 1.0 ACSN 10398592 10652356 12731048 12740575 17544292 19290918 20814939 21127503 22513334 23620508 3263576 8478617 8986721 9438848 9738502 9751747
CD28 VAV1 â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 ACSN 10426994 11907067 1313950 15197224 15536084 16713974 22437870 7523569 9359474
VAV1 CDC42 â—¼   ENZYMATIC_REACTION ✅ 33.0 1.0 ACSN 10077632 10646608 10679059 10714681 10849438 10898494 11080163 11526404 11698448 11754814 11994416 12094222 12165654 12186560 12616499 12626562 12740575 12885870 12917349 14764585 15169881 16887996 19909365 20189481 22513334 22786724 22952938 25355530 25539813 26552706 8189062 8226994 9438848
VAV1 RHOA â—¼   ENZYMATIC_REACTION ✅ 33.0 1.0 ACSN 10077632 10646608 10679059 10714681 10849438 10898494 11080163 11526404 11698448 11754814 11994416 12094222 12165654 12186560 12616499 12626562 12740575 12885870 12917349 14764585 15169881 16887996 19909365 20189481 22513334 22786724 22952938 25355530 25539813 26552706 8189062 8226994 9438848
CBLB VAV1 â—¼   DOWN_REGULATES ✅ - 7.0 1.0 ACSN 10426994 10646608 11526404 11907067 15536084 16713974 19592273
ZAP70 VAV1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 10395678 23109003 14757747 15751964 7798261 16189514 11859198 23758320 16339550
TEC VAV1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 7651724
VAV1 CDC42 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 10849438 22952938 9695188 12626562 12917349 12165654 25539813 19909365 14757747 18511940 10077632 26552706 12885870 11526404 10898494 25355530 11698448 16189514 10646608 11994416 20189481 22513334 12616499 10679059 23109003 12740575 11754814 9438848 11080163 10714681 14764585 15169881 26192618 22786724 8226994 12094222 8189062 11287617 16887996 12186560
VAV1 RHOA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 44.0 1.0 Omnipath 10849438 22952938 9695188 12626562 12917349 12165654 25539813 19909365 14757747 18511940 10077632 26552706 12885870 11526404 10898494 25355530 10592173 11698448 10646608 11994416 16397238 20189481 22513334 12616499 10679059 23109003 12740575 11754814 9438848 11080163 10714681 32203420 9601639 14764585 15169881 22786724 12094222 26192618 8189062 8226994 16887996 12186560
VAV1 PRKCQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 23331499 11956228 23109003 10725744 15802604 14673152 21487479
IFNAR1 JAK1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15312780 8943354 18508557 15449939 17969444 16171819
IFNG JAK1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 16467876 7617032 7673114 12438563 10986460 7615558 1396683 8550631
JAK1 IL2RA â—¼   PHYSICAL_INTERACTION 26.0 1.0 ACSN 10807786 10820393 10849428 12095053 15289500 15563472 16212621 16799562 17371980 1825141 18758473 19528259 19833085 20856220 21840487 22224781 23124025 23650441 24829413 26755705 2965306 6164929 7512720 7521688 8683106 9625766
JAK1 IFNAR1 â—¼   PHYSICAL_INTERACTION 16.0 1.0 ACSN 11207245 11698286 11964292 12811837 14610620 14764699 15864272 17513775 19833085 21115385 21840487 21930765 21930769 7512720 7521688 7543512
JAK1 IL4 â—¼   PHYSICAL_INTERACTION 34.0 1.0 ACSN 10485906 11160275 11371360 11867689 11870632 12223527 12401408 12496409 12818165 14610620 16243976 16413922 17404308 17485448 18250477 1825141 19833085 20184663 20406969 20510870 20856220 21115385 21469115 21840487 23124025 23390297 24030977 24091328 27216177 2965306 7512720 7521688 7543512 9834059
JAK1 IFNG â—¼   PHYSICAL_INTERACTION 41.0 1.0 ACSN 10485906 11489965 11579131 11777960 11867689 11870632 11964313 12413632 12811837 12818165 14607900 14610620 15634932 15778339 15811952 15814715 16286920 16424049 16713974 17016554 17559085 17683974 1825141 18272812 19833085 20038811 20406969 20819927 21149606 21411734 21840487 24091328 24658051 26755705 27216177 2965306 6425450 7512720 7521688 9834059 9864217
JAK1 IL2 â—¼   PHYSICAL_INTERACTION 26.0 1.0 ACSN 10807786 10820393 10849428 12095053 15289500 15563472 16212621 16799562 17371980 1825141 18758473 19528259 19833085 20856220 21840487 22224781 23124025 23650441 24829413 26755705 2965306 6164929 7512720 7521688 8683106 9625766
JAK1 IFNG â—¼   SHARES_COMPLEX 41.0 1.0 ACSN 10485906 11489965 11579131 11777960 11867689 11870632 11964313 12413632 12811837 12818165 14607900 14610620 15634932 15778339 15811952 15814715 16286920 16424049 16713974 17016554 17559085 17683974 1825141 18272812 19833085 20038811 20406969 20819927 21149606 21411734 21840487 24091328 24658051 26755705 27216177 2965306 6425450 7512720 7521688 9834059 9864217
JAK1 IFNAR1 â—¼   SHARES_COMPLEX 16.0 1.0 ACSN 11207245 11698286 11964292 12811837 14610620 14764699 15864272 17513775 19833085 21115385 21840487 21930765 21930769 7512720 7521688 7543512
JAK1 IL2 â—¼   SHARES_COMPLEX 26.0 1.0 ACSN 10807786 10820393 10849428 12095053 15289500 15563472 16212621 16799562 17371980 1825141 18758473 19528259 19833085 20856220 21840487 22224781 23124025 23650441 24829413 26755705 2965306 6164929 7512720 7521688 8683106 9625766
JAK1 IL4 â—¼   SHARES_COMPLEX 34.0 1.0 ACSN 10485906 11160275 11371360 11867689 11870632 12223527 12401408 12496409 12818165 14610620 16243976 16413922 17404308 17485448 18250477 1825141 19833085 20184663 20406969 20510870 20856220 21115385 21469115 21840487 23124025 23390297 24030977 24091328 27216177 2965306 7512720 7521688 7543512 9834059
JAK1 IL2RA â—¼   SHARES_COMPLEX 26.0 1.0 ACSN 10807786 10820393 10849428 12095053 15289500 15563472 16212621 16799562 17371980 1825141 18758473 19528259 19833085 20856220 21840487 22224781 23124025 23650441 24829413 26755705 2965306 6164929 7512720 7521688 8683106 9625766
JAK1 IL4 â—¼   ENZYMATIC_REACTION ✅ 34.0 1.0 ACSN 10485906 11160275 11371360 11867689 11870632 12223527 12401408 12496409 12818165 14610620 16243976 16413922 17404308 17485448 18250477 1825141 19833085 20184663 20406969 20510870 20856220 21115385 21469115 21840487 23124025 23390297 24030977 24091328 27216177 2965306 7512720 7521688 7543512 9834059
IFNAR1 JAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 8943354 18508557 8232552 17351669 8524272 7526154 9334213 23331499 10542297 11694501 10982844 15449939 15312780 8702790 8621447 17969444 8605876 10022928 15120645 16171819 29145629 8197134 16987978 24243840
PTPRC JAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 11994288 11201744
JAK1 PIK3R2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9774657 15021914
CD226 IFNG â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 10591186 12913096 14676297 19029380 22285893 24337740 24658051 26552706 26840537 28893624 8673704
IL4 IFNG â—¼   DOWN_REGULATES ✅ - 17.0 1.0 ACSN 10485906 10820262 11160275 11371360 11870632 12401408 12433365 12496409 12818165 18250477 1825141 20184663 20856220 21097505 23124025 2965306 9834059
NFKB1 IFNG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 12759422 21642544 21243522 9374532 10227974 16481345 17556653 19732956 21224476 14662860 12757742 18690006 17407192
FOS IFNG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 19285436 16713974 7759501 8756632 12842891 12432566
NFKB1 CCL5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 12820969 11413310 11478739 12122011 17065335 17510282 11700023 15144466 19786024 16707500 21189258 12388374 15972972 9120310 11389171 12050170 11259372
RHOA PTEN â—¼   ENZYMATIC_REACTION ✅ 32.0 1.0 ACSN 10953004 11698448 11729192 11739775 11992112 12194823 12361600 12740575 12778124 14657501 14744429 15761148 15793569 17517963 18037882 18423981 20008297 20351293 20535745 21178402 21642958 21840487 22949611 24857661 24919149 26885855 27048821 27066895 7479854 9362522 9660866 9822605
PTEN AKT1 â—¼   DOWN_REGULATES ✅ - 22.0 1.0 ACSN 10753747 11747822 12040186 15721744 16288286 16982858 17218262 17409395 19440036 19847259 19945467 20609352 21084277 22179046 22465479 23732914 24030100 24254977 25364523 26597054 27328425 27572739
AKT1 PTEN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 23.0 1.0 Omnipath 19903340 15987703 10790335 20596030 10592173 20605778 10866658 12077256 11035045 16107342 12297295
PTEN PIK3CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 16288286 10648629 17218262 12040186 15584861
FOS TGFB1 â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 ACSN 15067049 15749884 16243976 16327802 16393692 16394015 16413922 16713974 17404308 17485448 19667062 20547845 21372296 21385848 22634314 23390297 23430059 9064320
NFKB1 FASLG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 14563113 12655294 15160330 16770006 10671224
CASP8 MAP3K14 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 11002417 10753878
CD80 CD86 â—¼   PHYSICAL_INTERACTION 25.0 1.0 ACSN 10477595 11207245 11964292 12810107 14764699 15034038 15197224 17513775 17629517 18585785 20231889 20805416 21220452 22076556 22437870 23390297 24218453 25215878 25384214 25582338 26405600 7512027 7523569 8920882 9359474
CD80 CD86 â—¼   PROTEIN_INTERACTION 25.0 1.0 ACSN 10477595 11207245 11964292 12810107 14764699 15034038 15197224 17513775 17629517 18585785 20231889 20805416 21220452 22076556 22437870 23390297 24218453 25215878 25384214 25582338 26405600 7512027 7523569 8920882 9359474
CD80 CD28 â—¼   ENZYMATIC_REACTION ✅ 16.0 1.0 ACSN 11964292 12810107 14764699 15197224 17513775 17629517 18585785 20231889 22437870 23390297 25215878 25582338 26405600 7512027 7523569 9359474
CD80 CD28 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 21530327 7964482 22437870 2164219 1847722 23954143 15610849 7545666 21982860 21487479
CD80 CD274 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 23417675 24819296 18585785 17629517 20587542 31000591 31757674 21982860 18173375
IL2 IL2RA â—¼   PHYSICAL_INTERACTION 26.0 1.0 ACSN 10807786 10820393 10849428 12095053 15289500 15563472 16212621 16799562 17371980 1825141 18758473 19528259 19833085 20856220 21840487 22224781 23124025 23650441 24829413 26755705 2965306 6164929 7512720 7521688 8683106 9625766
IL2 IL2RA â—¼   SHARES_COMPLEX 26.0 1.0 ACSN 10807786 10820393 10849428 12095053 15289500 15563472 16212621 16799562 17371980 1825141 18758473 19528259 19833085 20856220 21840487 22224781 23124025 23650441 24829413 26755705 2965306 6164929 7512720 7521688 8683106 9625766
CD28 IL2 â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 ACSN 10426994 11907067 1313950 15197224 15536084 16713974 22437870 7523569 9359474
NFKB1 IL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 17641034 1777483 7623820 7744006 8834450 15477007 8254209 9111330 9135552 8383323 11035116 7730629 15079071 2848811 9737979 1707162 19968887 7957556 1604322 8977179 12027419 17491020 18207244 8814256 9233628 11145913
HMGA1 IL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8934574 8896456 10848593 10706706
FOS IL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 20557936 8893011 11260070 11685114 8397339 1737937 9605137 9590239 11262396 7989759 1916630 8473495 10601992 8114694 22474330 18725523 9233628 11385624 2518655 15170389 8468462 7565732 12432566 8660843 7739550 1305903 20680391 19181930
IL2 IL2RA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 6815536 3095922 15265897 12649439 16477002 15933202 1940342 17032757 15178252 8260650 3116143 8894436 1993646 8580082 8960125
NFKB1 IL4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 14688382 8524816 12516545 8135784 8083467 7807002
NFKB1 MAP3K8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 26.0 1.0 Omnipath 17145710 21988832 25609649 9950430 16291755 15169888 14743216 22435554 12832462 25852190 23557442
AKT1 MAP3K8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 17570479 12138205 23109003
MAP3K8 MAP3K14 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 9742107 10072079 11278268 18439422
CXCR4 RHOA â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 15261139 15882617 17035340 20535745 20644254 21521526 22025564 23034983 23402812 23567181 24277834
RHOA MAPK8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15659383 25241761 8824197
CD86 CD28 â—¼   ENZYMATIC_REACTION ✅ 19.0 1.0 ACSN 10477595 11207245 11964292 14764699 15034038 15197224 17513775 20231889 20805416 21220452 22076556 22437870 23390297 24218453 25215878 25384214 7523569 8920882 9359474
NFKB1 CD86 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10586028 15949284 19164127 15895390 18929846
CD86 CD28 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 21530327 22437870 18205792 23954143 11021528 21931534 21487479 7513726
CD4 ZAP70 â—¼   ENZYMATIC_REACTION ✅ 16.0 1.0 ACSN 10398592 10652356 12731048 12740575 17544292 19290918 20814939 21127503 22513334 23620508 3263576 8478617 8986721 9438848 9738502 9751747
ZAP70 GAB2 â—¼   ENZYMATIC_REACTION ✅ 31.0 1.0 ACSN 10358138 10562324 10849428 10982827 11353765 11447289 11572860 12138178 12415267 12640133 12707331 12731048 15240681 15699106 15713798 15735648 16212621 17371980 19833085 19909365 20814939 21059766 23414611 23620508 23886063 7600293 8478617 8642247 9625766 9738502 9751747
CD3E ZAP70 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 7761456 8906806 21900181 8366117 11855827 9698567 17617578
ZAP70 GAB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 23980151 18644434 11334882 11572860 23109003 15170389 12640133
CDC42 CAV1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16714282 7512369 9113980 23434736 11306516
CDC42 MAPK8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 25241761 12213839 25284480 18426980 10930450
CD3D B2M â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 18037897 26300885 15864273 14764708 20080535 15723809 7542404 21167756 22006319 25703557
CD3E B2M â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 18037897 26300885 15864273 14764708 20080535 15723809 7542404 21167756 22006319 25703557
CD3G B2M â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 18037897 26300885 15864273 14764708 20080535 15723809 7542404 21167756 22006319 25703557
B2M PTPRC â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 10358761 10559964 11154916 11509172 11717192 14508489 16181333 22076556 22790179 24457417 8642276
CD28 MAP3K14 â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 ACSN 10426994 11907067 1313950 15197224 15536084 16713974 22437870 7523569 9359474
ITK CD28 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 19901323 10586033 22936936 8946678 15144186 15592455 16094384 8992971
CD28 PIK3R2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 23109003 17722974 22315502 8146197 16107703 7509360 8080844 15790353
CBLB PIK3R2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 11087752 21780115 10488096 19531499 11526404 15032589 23109003 22880054 17635922 10514377
CD4 CD3D â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
CD4 HLA-DRA â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
CD4 HLA-DQA1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
CD4 CD3G â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
CD4 CD3E â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
CD4 ITK â—¼   ENZYMATIC_REACTION ✅ 16.0 1.0 ACSN 10398592 10652356 12731048 12740575 17544292 19290918 20814939 21127503 22513334 23620508 3263576 8478617 8986721 9438848 9738502 9751747
CD4 PRKCQ â—¼   ENZYMATIC_REACTION ✅ 16.0 1.0 ACSN 10398592 10652356 12731048 12740575 17544292 19290918 20814939 21127503 22513334 23620508 3263576 8478617 8986721 9438848 9738502 9751747
CD4 PTPRC â—¼   ENZYMATIC_REACTION ✅ 16.0 1.0 ACSN 10398592 10652356 12731048 12740575 17544292 19290918 20814939 21127503 22513334 23620508 3263576 8478617 8986721 9438848 9738502 9751747
CD4 PTPRC â—¼   DEPHOSPHORYLATION ✅ 5.0 1.0 Reactome 20346773 23580664 11827988 21543337 2530588
PRKCQ STK39 â—¼   ENZYMATIC_REACTION ✅ 13.0 1.0 ACSN 10652356 15214048 15536066 16606694 17544292 17548359 18784374 19201850 23077238 23433459 23474202 23886063 25960930
PRKCQ TEC â—¼   ENZYMATIC_REACTION ✅ 21.0 1.0 ACSN 10652356 11687500 11747822 12670391 15214048 15536066 15802604 16606694 17544292 17548359 17680028 18784374 18802401 19109239 19122654 19201850 23077238 23433459 23474202 23886063 25960930
PRKCQ IKBKB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 17363905 11120819
PRKCQ STK39 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 10980603 14988727
ITK TEC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12573241
TEC DOK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 11071635 9651683 9020138 11825908 10823839
AKT1 GAB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 11782427
GAB2 PIK3R2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9973481 10982827 18950707
PIK3CA AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 25793261 19117013 21041639 24950409 21816939
AKT1 RARA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 16417524
AKT1 IRAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 11976320
AKT1 AKT2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 11546794 14500673 12176337 11445557 9736715 12149249 11278835
AKT1 DNMT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 26553800 24492612 27521372 26216216 25949795 21151116 21565170
AKT1 IKBKB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15184909 25241761 22689577 15856005 10485711 17660512
FOS MMP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 11665970 19028685 9334186 16380175 10914841 15090544 20463008 15467742 10684971
FOS MMP3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 9334186 20609072 23608488 8957070 8921230
IKBKB NFKB1 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 9315679 9914500 9721103 10593898 9135156
NFKB1 CXCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17363596 28266569 15132979 15722553
NFKB1 IL2RA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 1777483 9135552 11781710 8455627 8029023 7636248
NFKB1 NOS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17250678 17081374 23811396
IKBKB NFKB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 57.0 1.0 Omnipath 31598684 11976329 16713569 10469655 29485707 26999213 12842894 10835356 27187478 27402796 18782567 27554194 12482991 25241761 10022904 15199157 19519322 15489227 19250910 15212693 11158290 11297557
MAP3K14 IKBKB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 17145710 11278268 10195894 9520446 14743216 9689078 9346485 16285893 10733566 10779355 10072079 11460167 10022904 10713178
IKBKB DOK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15574499
HLA-DRA PTPRC â—¼   DEPHOSPHORYLATION ✅ 5.0 1.0 Reactome 20346773 23580664 11827988 21543337 2530588
HLA-DQA1 PTPRC â—¼   DEPHOSPHORYLATION ✅ 5.0 1.0 Reactome 20346773 23580664 11827988 21543337 2530588
CD3D PTPRC â—¼   DEPHOSPHORYLATION ✅ 5.0 1.0 Reactome 20346773 23580664 11827988 21543337 2530588
CD3E PTPRC â—¼   DEPHOSPHORYLATION ✅ 5.0 1.0 Reactome 20346773 23580664 11827988 21543337 2530588
PTPRC CD3G â—¼   DEPHOSPHORYLATION ✅ 5.0 1.0 Reactome 20346773 23580664 11827988 21543337 2530588
IFNA7 IFNAR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 21856167
IFNA10 IFNAR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 21856167
IFNA17 IFNAR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 7623815 21856167
HLA-DRA HLA-DOA â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 9606180 7481823 9075930 9311912 7667286 8046351 10631952
HLA-DRA HLA-DOB â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 9606180 7481823 9075930 9311912 7667286 8046351 10631952
HLA-DRA CD3E â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
HLA-DRA CD3D â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
HLA-DRA CD3G â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
PIK3R3 PIK3CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 8596638 22402981 9415396 11733063 26496610 25814554
DNMT1 H3C2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16357870 24074865 23326524 12435631 22466170
MAP2K3 MAPK11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 18291705 11704645 23331499 11242034 19369195 21614932 14724572 12738796 11274345 18083107 18855897
MAP3K14 NFKB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 17145710 11239468 14743216 15994789 11687592 15140882
MAPK8 RARA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10383391 15657432 21272161
MAP2K3 MAPK13 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 23331499 11242034 21614932 12738796 11274345 9374491 18083107 9790884 18855897
PIK3R3 PIK3CB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 8596638 22402981 11733063 25814554
HLA-A CD8A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9177355 10809759
HLA-A KIR3DL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 11955593 25033772 15580655 15719024 8760804 8617928
HLA-DQA1 CD3D â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
HLA-DQA1 CD3E â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
EIF2AK2 PPP2R5A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 18957415 10866685
HLA-DQA1 CD3G â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
HLA-DQA1 HLA-DOA â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 9606180 7481823 9075930 9311912 7667286 8046351 10631952
HLA-DQA1 HLA-DOB â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 9606180 7481823 9075930 9311912 7667286 8046351 10631952
C9 C8B â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 9038722 16999828 7691959 17505110 16079145
C9 C6 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 9038722 16999828 7691959 17505110 16079145
C9 C8A â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 9038722 16999828 7691959 17505110 16079145
LAMA1 ITGB8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 7542940
CCL28 CCR10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 10975800 10781587 22633458
CCL25 CCR10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 10706668
C9 C7 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 9038722 16999828 7691959 17505110 16079145
CCL25 CCR9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 10498628 10699158 11159507 22633458 10229797