Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
USP11 CBX7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7998286 20601937
TPT1 ATP1A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218698 16730713
NEDD8 CUL1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 intact 0806155105 18723677
ETF1 SEC61B â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
CAD RIPK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CRK SHANK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
SHANK3 COPS6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
SHANK3 CCT3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
SHANK3 VIM â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
SHANK3 TUBA1C â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
SH3GLB1 ATP5MG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CAPNS1 ATP5MF â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
DCTN3 ACTR1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15473859 15738427
AFG3L2 PHC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
AHNAK LRRK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
ARRB2 MDM2 â—¼   UBIQUITINATION ✅ 2.0 0.8 intact 5214648 11588219
ATXN10 PHF19 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ATXN10 VIM â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HSPA5 BCAR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
TUBA4A BCAR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
BCAR1 TLN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16581250 8649368
CBX4 USP11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7998286 20601937
CCT3 EED â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
CCT8 CCT6A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
CD4 SH3GLB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CD4 LCK â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
TFDP1 CD74 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 1297652 10778981
CDC42 PAK1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 11278486 11804587
CDC42 MAP2K3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11704645 14724572
ESR1 CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24559156 10851069
RELA CFTR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11114294
COPS6 VIM â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15383276 5217202
NR3C1 CPS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9774647 10562461
CRK SUV39H2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
PGAM1 DCTN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
DCTN1 HDAC6 â—¼   COLOCALIZATION 2.0 0.8 intact 5215415 12024216
HSP90AB1 DNAJA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22011577 21700222
DNAJA1 STIP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22011577 21700222
DNAJA1 RIPK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
DNAJA2 HSP90AB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22011577 21700222
DUSP16 GABARAP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
E2F6 L3MBTL3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0610279104 17517653
E2F6 RBBP4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18319725 12909625
EEF1A1 PTPRCAP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
ESR1 YWHAQ â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22329840
ESR1 HSPD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11085516
VCP FAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18711132 0805371105
VCP FAF2 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
FAF2 VCP â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
NR3C1 FBXO32 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18615595 19059383
HDAC6 TUBA4A â—¼   COLOCALIZATION 2.0 0.8 intact 5215415 12024216
TUBA1A HDAC6 â—¼   DEACETYLATION ✅ 2.0 0.8 intact 5215415 12024216
HDAC6 TUBA4A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12024216
HSP90AB1 RIPK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPA5 UBE2V1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HSPA5 RIPK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPB1 OTUB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HSPB1 TUBB6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HSPD1 OGT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
HSPD1 LCK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
KIF5B YWHAQ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
PHC2 L3MBTL3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
LCK PTPRC â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 6672875 7507203
LRRK2 MAP2K3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19302196
MAP2K2 MAPK6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18039929
MDM2 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21988832 23839035
NUMA1 TLN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
RELA OGT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6166964 17882263
RHOA OTUB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20553488 7717051
USP11 PCGF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7998286 20601937
RIPK1 PDCD6IP â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 31138766 24316671
TUBG1 PDCD6IP â—¼   COLOCALIZATION 2.0 0.8 intact 17853893 6169256
PHC2 PHC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
PHF19 SUV39H2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
PITPNB SH3GLB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PLIN3 SH3GLB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PRKCE TJP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23967087 24727247
STIP1 RBBP4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SH3GLB1 RBBP4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RBBP4 RPN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RCN2 RIPK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
RIC8A TUBB2A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
TIMM50 RIPK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
SLC25A5 RIPK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
RIPK1 TUBB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TUBA1C SH3GLB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
VIM TUBA1C â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
TUBA1C VIM â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
VCP UBXN6 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
UBXN6 VCP â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
CCT2 CCT4 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
TUBB1 TUBB6 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
ACTR1A DCTN3 â—¼   PHYSICAL_INTERACTION 805.0 0.8 STRING 36370105
METTL14 METTL3 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
CUL4A DCUN1D1 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
CUL4B DCUN1D1 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
HSP90AB1 LRRK2 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
TUBB4B UBE2V1 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
CBX4 PCGF2 â—¼   PHYSICAL_INTERACTION 810.0 0.81 STRING 36370105
MDM2 CDKN2A â—¼   PHYSICAL_INTERACTION ✅ 0.81 0.81 mint 7989562 20713054
NEDD8 OTUB1 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 24654937 18954305 33665565
JARID2 PHF19 â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
CCT4 CCT6A â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
CCT2 TCP1 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
TUBB2A TUBB4B â—¼   PHYSICAL_INTERACTION 819.0 0.81 STRING 36370105
ESR1 CAND1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31527615 19805454
STIP1 CFTR â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 20534503 31324722
CFTR HAX1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26618866 17110338
CFTR RCN1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26618866 17110338
CFTR DCTN1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26618866 31324722
ESR1 CLIC1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31527615 19805454
ESR1 CTBP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 23403292 31527615
PGAM5 CUL3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17046835 21145461
CUL3 CUL5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22709582 21145461
MDM2 CUL4B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28225217 22032989
CUL4B RBBP4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 23238014 34026424
E2F6 PCGF2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 11171983 24981860
PAK1 ESR1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 12374744 16452229
ESR1 RCN2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31527615 19805454
LRRK2 HSPB1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24725412 29519959
LCOR PHF19 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24981860 27705803
LCOR RBBP4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24981860 27705803
LRRK2 RHOA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21454543 31046837
PHC2 PCGF3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25416956 24981860
PCGF3 PHC1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 32296183 24981860
HSP90AB1 NR3C1 â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
ETF1 HARS â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
TUBA1A TUBA4A â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
TUBB TUBB1 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
TUBB2A TUBB4B â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
CBX7 PCGF2 â—¼   PHYSICAL_INTERACTION 825.0 0.82 STRING 36370105
EEF2 ETF1 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
DCUN1D1 NEDD8 â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
PHC3 CBX6 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 24981860 22325352 27705803
PCGF3 CBX4 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 24981860 22325352 27705803
HDAC6 CFTR â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 31501480 14675537 22069321
DCTN1 KIF14 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 31586073 26638075 34079125
HAX1 DNM1L â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
PHF19 RBBP7 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 23104054 27705803
TUBA1A TUBB â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
LRRK2 TUBA1A â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
DNAJA2 STIP1 â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
NR3C1 RELA â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
PSMC5 VCP â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
CBX6 PCGF3 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 21282530 24981860
CUL1 CUL3 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
ASPM RCN2 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 28436967 26496610
LRRK2 STIP1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 31046837 24510904
TUBB1 TUBB2A â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
CBX7 PHC3 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
KIF5B TUBA1B â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
CCT3 CCT5 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
TUBA4A TUBB2A â—¼   PHYSICAL_INTERACTION 844.0 0.84 STRING 36370105
TUBA1B TUBB4B â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
COPS6 CUL1 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
CAND1 CUL5 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
CCT5 CCT7 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
CUL1 VCP â—¼   PHYSICAL_INTERACTION 849.0 0.84 STRING 36370105
PCGF3 CBX7 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 28514442 21282530 26186194 33961781
BCAR1 LCK â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 9020138
LRRK2 CDC42 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 21048939 21454543
CFTR HSPB1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 29924966 23155000 26618866 17110338 26627832
CFTR FAF2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 26618866 29924966 31324722
CFTR CLIC1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 26618866 29924966 31324722
CFTR RPN1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 26618866 29924966 31324722
CFTR MYH9 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 26618866 29924966 22038833
CFTR RCN2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 26618866 29924966 17110338
ESR1 MYH9 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 25604459 19805454 21182205
ESR1 RBBP7 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 23403292 31527615 18577416 21182205
PTPRC LCK â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 7507203 6672875
PTPRC LCK â—¼   PHOSPHORYLATION ✅ 0.85 0.85 mint 7507203 6672875
PTPRC LCK â—¼   DEPHOSPHORYLATION ✅ 0.85 0.85 mint 10369126 8310409
LCK PTPRC â—¼   DEPHOSPHORYLATION ✅ 0.85 0.85 mint 7507203 6672875
CCT5 CCT8 â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
ACTR1A DCTN3 â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
KIF5B TUBB2A â—¼   PHYSICAL_INTERACTION 854.0 0.85 STRING 36370105
CBX6 PHC3 â—¼   PHYSICAL_INTERACTION 855.0 0.85 STRING 36370105
TUBA4A TUBB â—¼   PHYSICAL_INTERACTION 856.0 0.85 STRING 36370105
CCT2 CCT3 â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
CUL3 CUL1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 26344197 21145461
MDM2 CUL1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 24804778 20708156
CRK HSPB1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 22939629 31980649
NEDD8 CUL4B â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 24654937 10597293 18274552 21145461 16503656 23201271 31973889 16620772
ESR1 DNM1L â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 21217774 19805454
HSP90AB1 HSPD1 â—¼   PHYSICAL_INTERACTION 862.0 0.86 STRING 36370105
CBX4 PHC3 â—¼   PHYSICAL_INTERACTION 865.0 0.86 STRING 36370105
CCT2 CCT7 â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
DYNC1H1 TUBA1A â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
TUBA1B TUBB1 â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
PHC1 CBX6 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 24981860 27705803 28514442 22325352
PHC1 CBX7 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 24981860 27705803
CUL4A CUL1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 17079684 32235678 21145461
BAP1 RBBP7 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 19615732 29686263 32509391 34591877
PCGF2 CBX4 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 24981860 19636380 20601937 21282530 27705803 28514442 22325352
PHC2 CBX4 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 24981860 26496610 21282530 27705803 22325352
RBBP7 EED â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 24981860 12435631 26496610 26186194 27705803 28514442
LCOR EED â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 26496610 24981860 27705803
PHF19 EED â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 23104054 21143197 24981860 26496610 27705803 28514442
EIF4A1 EIF4A2 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
CBX4 CTBP1 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
KIF5B TUBA1A â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
CCT2 CCT8 â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
ASXL1 BAP1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
CAND1 DCUN1D1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
ARRB1 MDM2 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
CCT6A TCP1 â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
TUBB TUBB2A â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
TUBA1B TUBA1C â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
TUBB3 TUBB4B â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
PHC1 PHC2 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
CBX6 PCGF2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 24981860 21282530 27705803 28514442
CBX4 PHC2 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
RNF5 CFTR â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 19269966 16901789 21594788
LCK PTPRC â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
TUBB TUBB2A â—¼   CORRELATES + 0.88 0.88 CCLE 31978347
ARRB2 MDM2 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
HDAC6 TUBA1A â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
CBX7 PHC1 â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
DNM1L LRRK2 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
SPRTN VCP â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
MDM2 ESR1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 12897156 17545634 10766163 11178989 16713569 31012223
RHOA PKN3 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 28514442 31871319
CFTR VCP â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
RBBP4 RBBP7 â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
COPS6 CUL4A â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
COPS5 CUL4B â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
COPS6 CUL4B â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
CCT6A CCT7 â—¼   CORRELATES + 0.89 0.89 CCLE 31978347
JARID2 RBBP4 â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
METTL3 WTAP â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
DCTN1 DCTN3 â—¼   CORRELATES + 0.89 0.89 CCLE 31978347
CUL4A NEDD8 â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
CCT6A CCT8 â—¼   CORRELATES + 0.89 0.89 CCLE 31978347
CUL2 DCUN1D1 â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
CUL3 DCUN1D1 â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
CAND1 CUL1 â—¼   DOWN_REGULATES ✅ - 3.0 0.9 ACSN 12504025 12504026 15537541
ESR1 SEC61B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20034404
CUL4A CAND1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 12504026 16964240 21145461 12504025 27203177 21249194 18606781 17079684 22405651 15448697 19295130 31973889 22474075 12609982
ARRB2 ARRB1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 17353931 24069330 28514442 17620599
MDM2 ARRB2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 18544533 21389118 21081496 33649538 32828283 17984062 32450252 12538596 21988832 15878855 26545496 12488444 21466165 11588219
BAP1 ASXL1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 23850490 34591877 33961781 26437366 20805357 22897849 19615732 26416890 26739236 34170818 32683582 19815555 32669118 21642991 33758188 27705803 20436459
BAP1 ASXL2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 33731362 34591877 20805357 19615732 26416890 32669118 26186194 27705803 19815555 28514442 29284740
CUL3 CAND1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 21145461 21249194 22013077 16449638 22405651 26286618 12609982
PHC1 CBX4 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 22078878 24981860 26496610 9199346 21282530 27705803 28514442 22325352
ESR1 CCT6B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20034404
RELA CD74 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8164652
RNF5 CFTR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 16901789 17145710 21148293
COPS5 MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18926707 17879958
MAPK6 COPS6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
CRK TLN1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16581250 10777559 12640026
NEDD8 CUL5 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 18805092 24654937 33961781 18274552 10597293 21119685 21145461 23201271 24076655 18247557 28522566 22405651 31253590 28514442 20847044
LRRK2 DNM1L â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 24282027 22228096 22639965 23813973 29541021
E2F6 RBBP4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12909625
EED MAP1LC3B â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
EIF4A1 MAPK6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
RCN2 GABARAPL2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
STIP1 HSP90AB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21170051 27353360
RHOA KIF14 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 23444367 16431929 23716662
NR3C1 LCK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16888650
PHGDH MAPK6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
PHC2 MAPK6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
MAPK6 TUBA1A â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
MAPK6 PDCD6IP â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
NR3C1 RELA â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12734399 9261164 9442377
PCGF2 PHC2 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
PCGF2 PHC1 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
VCP SPRTN â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 22902628 23042605 23042607
PHF19 RBBP4 â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
CUL5 DCUN1D1 â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
ACTR1A DCTN1 â—¼   CORRELATES + 0.9 0.9 CCLE 31978347
PCGF2 PHC3 â—¼   PHYSICAL_INTERACTION 903.0 0.9 STRING 36370105
CCT3 CCT6A â—¼   CORRELATES + 0.9 0.9 CCLE 31978347
CCT2 CCT6A â—¼   CORRELATES + 0.9 0.9 CCLE 31978347
CCT4 CCT8 â—¼   CORRELATES + 0.9 0.9 CCLE 31978347
ACTR1A DYNC1H1 â—¼   PHYSICAL_INTERACTION 907.0 0.9 STRING 36370105
LRRK2 YWHAQ â—¼   PHYSICAL_INTERACTION 907.0 0.9 STRING 36370105
CCT3 CCT4 â—¼   CORRELATES + 0.9 0.9 CCLE 31978347
CBX4 PHC1 â—¼   PHYSICAL_INTERACTION 909.0 0.9 STRING 36370105
TUBB1 TUBB3 â—¼   CORRELATES + 0.91 0.91 CCLE 31978347
CCT5 CCT6A â—¼   CORRELATES + 0.91 0.91 CCLE 31978347
CDKN2A MDM2 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
TUBB TUBB3 â—¼   CORRELATES + 0.91 0.91 CCLE 31978347
TUBA1B TUBB â—¼   CORRELATES + 0.91 0.91 CCLE 31978347
TUBA4A TUBB3 â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
CBX7 PHC2 â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
COPS5 CUL4A â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
CAND1 CUL3 â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
CAND1 CUL4A â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
COPS5 CUL3 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
CCT4 TCP1 â—¼   CORRELATES + 0.92 0.92 CCLE 31978347
EED RBBP7 â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
BCAR1 CRK â—¼   PHYSICAL_INTERACTION 923.0 0.92 STRING 36370105
DYNC1H1 DYNC1LI1 â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
EED PHF19 â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
TUBA1B TUBB2A â—¼   CORRELATES + 0.92 0.92 CCLE 31978347
RPN1 SEC61B â—¼   PHYSICAL_INTERACTION 928.0 0.92 STRING 36370105
CCT6B CCT8 â—¼   PHYSICAL_INTERACTION 928.0 0.92 STRING 36370105
CCT6B CCT7 â—¼   PHYSICAL_INTERACTION 929.0 0.92 STRING 36370105
COPS6 NEDD8 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
EEF2 TPT1 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
COPS5 NEDD8 â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
CCT4 CCT7 â—¼   CORRELATES + 0.93 0.93 CCLE 31978347
E2F6 TFDP1 â—¼   PHYSICAL_INTERACTION 934.0 0.93 STRING 36370105
TUBB2A TUBB3 â—¼   CORRELATES + 0.93 0.93 CCLE 31978347
CCT7 TCP1 â—¼   CORRELATES + 0.93 0.93 CCLE 31978347
CCT8 TCP1 â—¼   CORRELATES + 0.93 0.93 CCLE 31978347
CAND1 CUL2 â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
CBX6 PHC2 â—¼   PHYSICAL_INTERACTION 939.0 0.93 STRING 36370105
CCT3 TCP1 â—¼   CORRELATES + 0.93 0.93 CCLE 31978347
CUL3 NEDD8 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
RHOA TUBA4A â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
TUBA1A TUBA1B â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
CCT3 CCT8 â—¼   CORRELATES + 0.94 0.94 CCLE 31978347
CCT2 CCT6B â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
CCT7 CCT8 â—¼   CORRELATES + 0.94 0.94 CCLE 31978347
PHF6 RBBP4 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
TUBA1B TUBB â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
TUBA1B TUBB3 â—¼   CORRELATES + 0.94 0.94 CCLE 31978347
RPGR TUBG1 â—¼   PHYSICAL_INTERACTION 948.0 0.94 STRING 36370105
TFDP1 E2F6 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 24981860
DCTN1 DCTN3 â—¼   PHYSICAL_INTERACTION 951.0 0.95 STRING 36370105
CCT2 CCT5 â—¼   CORRELATES + 0.95 0.95 CCLE 31978347
CCT3 CCT7 â—¼   CORRELATES + 0.95 0.95 CCLE 31978347
DCTN1 RPGR â—¼   PHYSICAL_INTERACTION 955.0 0.95 STRING 36370105
IQCB1 RPGR â—¼   PHYSICAL_INTERACTION 955.0 0.95 STRING 36370105
UBXN6 VCP â—¼   PHYSICAL_INTERACTION 957.0 0.95 STRING 36370105
CUL1 CAND1 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 17290223 5219620
COPS6 CUL2 â—¼   PHYSICAL_INTERACTION 960.0 0.96 STRING 36370105
NEDD8 CUL2 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 23401859 24654937 18274552 10597293 10318914 21145461 31444342 18826954 16503656 23201271 18247557 19617556 18173839 17132228 10585493 16620772
ACTR1A DCTN1 â—¼   PHYSICAL_INTERACTION 960.0 0.96 STRING 36370105
MDM2 ARRB1 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 18544533 21081496 19879840 29676828 21857681 12538596 15878855 21466165 11588219
TUBA1A TUBB3 â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
TUBA1B TUBB2A â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
CAND1 CUL4B â—¼   PHYSICAL_INTERACTION 962.0 0.96 STRING 36370105
COPS5 CUL2 â—¼   PHYSICAL_INTERACTION 964.0 0.96 STRING 36370105
DCTN1 MAPRE1 â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
COPS5 CUL1 â—¼   PHYSICAL_INTERACTION 968.0 0.96 STRING 36370105
NEDD8 CUL1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 21765416 16177058 18723677 18627766 17438373 32726803 24654937 11027288 18274552 10772955 16503656 24076655 18247557 22405651 17318178 10713156 19713960 10318914 21102408 23267066 23201271 22959436 17206147 16620772 18805092 10597293 21119685 21145461 18826954 19245792 19617556 12565873 18264111 24949976 22474075
PAK1 CDC42 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 7744004 12879077 23455922 15548653 10802735 24276241 31871319 10684602 21167153 19596003 12606577 10360579 18057010 20936779 11157984 25150978 18426980 21029865 12650940 9705280 8107774 23175184 21048135 31478661 9535855 16678097
CCT3 CCT6B â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
EED RBBP4 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
FAF2 VCP â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
CCT4 CCT6B â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
CCT6B TCP1 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
HSP90AB1 STIP1 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
CUL2 NEDD8 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
CD4 LCK â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
CUL5 NEDD8 â—¼   PHYSICAL_INTERACTION 979.0 0.97 STRING 36370105
EED JARID2 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
TUBA1B TUBB3 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
CCT5 CCT6B â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
DCTN1 PAFAH1B1 â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
TUBA1A TUBB2A â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
DCTN1 DYNC1H1 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
DYNC1H1 PAFAH1B1 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
ASXL2 BAP1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
CCT2 CCT6A â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CCT3 CCT6A â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CCT4 CCT6A â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CCT6A CCT7 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CCT6A TCP1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CCT6A CCT8 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
METTL14 METTL3 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CUL1 DCUN1D1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
CDC42 PAK1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
CAND1 CUL1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
CCT4 CCT8 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
CCT5 CCT6A â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
COPS5 COPS6 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
CCT2 CCT3 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT2 CCT8 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT3 TCP1 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT3 CCT4 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT3 CCT7 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT4 CCT7 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT4 CCT5 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT7 CCT8 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT8 TCP1 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT2 CCT7 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT2 CCT4 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT2 CCT5 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT2 TCP1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT3 CCT5 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT3 CCT8 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT4 TCP1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT5 TCP1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT5 CCT7 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT5 CCT8 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT7 TCP1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RELA CUL1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 9990852 10514433 9859996 9990853 7628694
CUL1 NEDD8 â—¼   PHYSICAL_INTERACTION 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
CUL1 NEDD8 â—¼   SHARES_COMPLEX 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
CUL1 NEDD8 â—¼   ENZYMATIC_REACTION ✅ 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
CAND1 CUL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 45.0 1.0 Omnipath 17145710 12684064 25435324 36076154 23019411 18826954 17290223 17438373 21169563 27542266 16036220 21145461 21778237 22474075 22767593 16861300 18173839 12504026 12504025 12706828 22405651 21249194 23453757 22013077 17439941 12609982 15537541
NEDD8 CUL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16620772 15688063 11696557 21145461
CUL4A COPS5 â—¼   DEMETHYLATION ✅ 9.0 1.0 Reactome 19748355 18926707 16401342 18093314 23535663 23583660 22959436 16943200 23535662
CAND1 CUL4A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 17145710 18606781 19295130 22405651 27203177 17079684 21249194 19231300 12504026 21145461 12504025 22474075 12609982 16964240 15448697
NEDD8 CUL4A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 9694792 18805092 21145461 19250909 19231300
ESR1 CAD â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16675542 12746293
ACTR1A DYNC1LI1 â—¼   PHYSICAL_INTERACTION 28.0 1.0 Reactome 17274799 9490716 10679020 10562278 11306556 24891604 16723730 18086915 17283181 18664496 11035033 25453831 18046453 11285137 19564404 8642258 12198549 15728195 10903204 15878873 7691276 8909537 23839779 9150144 10559986 25233431 10036229 24806965
ARRB1 MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 15878855 23331499 21081496 12538596 17303558 11588219 21466165 18544533 21857681 19879840
CRK BCAR1 â—¼   PHYSICAL_INTERACTION 14.0 1.0 ACSN 11146654 11353765 12094222 12432077 14697347 15169881 15308668 16000375 16076871 18835194 19454690 20189481 22464172 9808620
CRK BCAR1 â—¼   SHARES_COMPLEX 14.0 1.0 ACSN 11146654 11353765 12094222 12432077 14697347 15169881 15308668 16000375 16076871 18835194 19454690 20189481 22464172 9808620
BCAR1 CRK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 42.0 1.0 Omnipath 9920935 11369773 11278916 15673687 8662907 9581808 8631823 8070403 10747099 12065577 10329689 16267043 10592173 10208419 17038317 18835194 20627867 16413489 10753828 8943292 9860979 11839772 14657239 12799422 19380743 15492270 10085298 12615911
LCK CD4 â—¼   PHYSICAL_INTERACTION 16.0 1.0 ACSN 10398592 10652356 12731048 12740575 17544292 19290918 20814939 21127503 22513334 23620508 3263576 8478617 8986721 9438848 9738502 9751747
CD4 PTPRC â—¼   ENZYMATIC_REACTION ✅ 16.0 1.0 ACSN 10398592 10652356 12731048 12740575 17544292 19290918 20814939 21127503 22513334 23620508 3263576 8478617 8986721 9438848 9738502 9751747
CD4 PTPRC â—¼   DEPHOSPHORYLATION ✅ 5.0 1.0 Reactome 20346773 23580664 11827988 21543337 2530588
CD4 LCK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 16888650 8104794 11854499 8246987 3262426 12601806 17653867 23109003 12007789 16189514 17005671 15489916 15047060
CDC42 PAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 60.0 1.0 Omnipath 17145710 810774 10360579 21167153 8107774 10559936 9705280 12650940 16678097 23331499 21029865 10684602 18057010 15020669 21070974 11340065 21048135 15003621 20936779 10934474 11413130 15788770 15713627 9535855 23109003 11950587 19628037 7744004 12879077 12606577 24276241 10224076 19596003 8973630 19812368 11248548 10802735 18719708 10613909 10461188 23455922
CDKN2A MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 57.0 1.0 Omnipath 12167711 18541670 23416275 9529249 17426254 12630860 17116689 12085228 15856024 10822382 19166854 12209154 12740913 17158541 16915296 17909018 25809483 9653180 14612427 22120712 16173922 10871849 18418067 24769896 9724636 21133853 10801444 19049976 9529248 16107876 18813780 20713054 18467333 15355988 18583933 20395212 11223036
CUL4B COPS5 â—¼   DEMETHYLATION ✅ 9.0 1.0 Reactome 19748355 18926707 16401342 18093314 23535663 23583660 22959436 16943200 23535662
PAK1 CTBP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 28007610 12872159 16999872 18354494 20361981 23291169
VCP CUL3 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 33444648 11733065 28115426 15652483 10811609 29153394
DCTN3 DYNC1H1 â—¼   PHYSICAL_INTERACTION 28.0 1.0 Reactome 17274799 9490716 10679020 10562278 11306556 24891604 16723730 18086915 17283181 18664496 11035033 25453831 18046453 11285137 19564404 8642258 12198549 15728195 10903204 15878873 7691276 8909537 23839779 9150144 10559986 25233431 10036229 24806965
DCTN3 DYNC1LI1 â—¼   PHYSICAL_INTERACTION 28.0 1.0 Reactome 17274799 9490716 10679020 10562278 11306556 24891604 16723730 18086915 17283181 18664496 11035033 25453831 18046453 11285137 19564404 8642258 12198549 15728195 10903204 15878873 7691276 8909537 23839779 9150144 10559986 25233431 10036229 24806965
NEDD8 DCUN1D1 â—¼   PHYSICAL_INTERACTION 11.0 1.0 Reactome 19617556 18826954 25349211 25314029 18206966 21940857 23201271 26906416 19250909 25531226 27030794
PAFAH1B1 DYNC1H1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11889140 11163259 27173435 12885786 19622634 26496610 36692009
ESR1 MDM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 12897156 17166846 12750288 8324731 22787161 21169420 19578757
ESR1 HSPB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15833836 10960840 11174852 8923463
PAK1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 18521086 26944939 16778166 18755239 21893191 15178330 19205871 29548483 26554417 27003261 24505617 16452229 15193262 19557173 15642175 12374744 19465939 17604944 25447917 20179234
LCK ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 9500442 10571988 25386784 11145737 7539106 27748765
RELA IRF7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15265881 16982926 11877397
KSR1 MAP2K2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 19219045 17145710 19541618 27086506 17613518 11909642
LCK PTPRC â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 ACSN 10652356 12414720 12731048 12740575 17544292 19290918 20814939 21127503 22513334 23620508 23886063 25312647 3263576 8478617 8986721 9438848 9738502 9751747
PTPRC LCK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 31.0 1.0 Omnipath 17145710 19167335 8433999 2141684 9973453 8473339 2141630 12589038 8663450 15085197 2548204 8441403 11259588 15743820 10330160 2530588 10369126 8576115 7507203 11369760 17719247
PAK1 MAP2K3 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 10661401 11062502 11385609 11907067 12885870 14764585 15536084
RIPK1 MAP2K3 â—¼   ENZYMATIC_REACTION ✅ 22.0 1.0 ACSN 11274345 12556535 12655147 12738796 14730360 15592525 17462996 18641653 18855897 19392652 19524513 19632174 21133840 21232017 21614932 23010170 23850759 24378531 26587781 26653790 28574505 28765050
RIPK1 MAP2K3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12655147 21614932 12738796 11274345 18855897
PAK1 MAP2K3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 7592586 11304531 15677464 11309380 14970210
PAK1 MAPK6 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 21372320 21177870 18720373 21317288 18248330 17161475
PPM1D MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 18265945 17936559 17939684
NCBP2 METTL14 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 9409616 24316715 24407421 24981863
NCBP2 METTL3 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 9409616 24316715 24407421 24981863
NCBP2 WTAP â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 9409616 24316715 24407421 24981863
PAK1 NF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 39.0 1.0 Omnipath 17081983 14580336 21481793 23162742 22105362 18071304 20068231 19036346 18669648 20302846 15378014 27285107 28090172 27345717 19165420 14981079 26555075 19651622 19691289 22567403 11719502 25893302 11782491
RELA NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 23871663 10995388 7659084 8290595 16713569
NR3C1 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 23871663 10995388 7659084 8290595 16713569
PAK1 PGAM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 12189148
PAK1 VIM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 14722118 11895474 17081983 16565220 26369929 28390425 27457922 11420699 15713670 15766329 7983050 12458200 12761892 26956613 16964243 28096473 15345747
RIPK1 PGAM5 â—¼   PHYSICAL_INTERACTION 31.0 1.0 ACSN 11274345 16469705 17603935 18641653 19037093 19498109 19524512 19524513 19632174 20823910 20861672 21133840 21232017 22265414 22421439 23010170 23073834 23627914 24366341 26024392 26587781 26653790 26807733 26853145 26900751 27558815 27833036 27959630 28498367 28574505 28645028
RIPK1 PGAM5 â—¼   SHARES_COMPLEX 31.0 1.0 ACSN 11274345 16469705 17603935 18641653 19037093 19498109 19524512 19524513 19632174 20823910 20861672 21133840 21232017 22265414 22421439 23010170 23073834 23627914 24366341 26024392 26587781 26653790 26807733 26853145 26900751 27558815 27833036 27959630 28498367 28574505 28645028
MGMT MGMT â—¼   KO_DOWN_REGULATES ✅ - -4.42 4.41 PKG 28854368