Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
NAP1L1 H2BC11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20002496
FEZ1 PTPRS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
H2BC5 ASPM â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
CALR ASPM â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
HSP90B1 ASPM â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
NPM1 ASPM â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PPP2R1A CDK4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8208439 17540176
PPP2R1A FOXO3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20110348 8288835
MYC IPO7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22284678
STUB1 RCN2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CNKR1 ASPM â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
FEZ1 AURKA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
FEZ1 ASPM â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CADH5 ASPM â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
T53I1 ASPM â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
MAD3 ASPM â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CALU CALR â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26344197 34079125
LZTS2 CNDH2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CNDH2 ASPM â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
MK06 ASPM â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26972000 29426014
PP6R2 ASPM â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CSN7B UBE3A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CSN7B ASPM â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SYIM ASPM â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CRAC1 ASPM â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
TX13A ASPM â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
NGN3 ASPM â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
MLRV ASPM â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
DNJB7 ASPM â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 33957083
MOAP1 ASPM â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CDC16 ASPM â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
DKK3 ASPM â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
MYC ASPM â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21150319 29467282
FOXJ1 ASPM â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
LZTS2 ASPM â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
EID1 ASPM â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
BRCA1 KIFC1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26831064 29656893
MYC IPO7 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17314511 29467282
DTBP1 ASPM â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
AURKA MK06 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 26972000 29426014 23443559
SPC24 ASPM â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
SKAP1 ASPM â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
PEX19 ASPM â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
ASPM NP1L4 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 28436967 26496610
ASPM IPO7 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 28436967 26496610
ASPM RCN2 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 28436967 26496610
AURKA PP6R2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33961781 26186194 28514442 32707033 23443559
GCP5 ASPM â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33961781 28514442 28436967
TRAD1 ASPM â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33961781 28514442 28436967
AURKA WDR62 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33961781 28514442 26186194 32707033
CDK4 ASPM â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 26496610 17353931
AURKA BRCA1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 22110403 26831064 14990569
TUBGCP2 TUBGCP3 â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
UBE3A MK06 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 26972000 22645313 29426014
CUL3 CSN7B â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 27833851 21145461
MZT2B GCP5 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 20360068 26496610 26186194 28514442
CDK4 BRCA1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 9244350 16713569 17334399 12509456
MYC IPO9 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 17314511 29467282 17353931
MZT2B TUBGCP6 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
MZT2B TUBGCP3 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
MZT2B TUBG1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
BRCA1 MYC â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
NAP1L1 NAP1L4 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
BRCA1 TUBG1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
HSP90B1 OS9 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
OS9 VCP â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
MYC CDK4 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 22094256 28205554 21988832 28628118
MZT2B TUBGCP5 â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
PPP1CA AURKA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11039908 11551964
MYC BRCA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11916966 9788437 20215511 30415952 16713569 12646176 14612409
CALR MAPK6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
UBE3A EID1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
MAPK6 FOXO3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
FOXO3 PRKAA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24257750 22848740 17711846
MAPK6 PPP2R1A â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
PRKAA1 MTOR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 14970221
MYC NAP1L1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
MZT2B TUBGCP4 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
MZT2B TUBGCP2 â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
CALR CALU â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
KATNA1 KATNB1 â—¼   PHYSICAL_INTERACTION 963.0 0.96 STRING 36370105
TUBGCP3 TUBGCP6 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
TUBG1 TUBGCP5 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
TUBGCP4 TUBGCP6 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
TUBGCP4 TUBGCP5 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
TUBG1 TUBGCP2 â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
TUBG1 TUBGCP4 â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
TUBG1 TUBGCP6 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
TUBGCP5 TUBGCP6 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
TUBG1 TUBGCP3 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CDC16 FZR1 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
KATNB1 KATNA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 9568719 26929214 10751153 26496610 16203747
KATNA1 KATNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 9568719 26929214 10751153 26496610 16203747
BRCA1 AURKA â—¼   PHYSICAL_INTERACTION 8.0 1.0 ACSN 11877377 15459660 19075565 19793801 20011137 20029420 21060331 21337561
BRCA1 AURKA â—¼   ENZYMATIC_REACTION ✅ 8.0 1.0 ACSN 11877377 15459660 19075565 19793801 20011137 20029420 21060331 21337561
MYC AURKA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20890087 20519624 14744757 20682043
AURKA WDR62 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 25501809 26713495
AURKA BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 22864622 22340593 18026198 24775809 14990569
MYC BMI1 â—¼   UP_REGULATES ✅ + 32.0 1.0 ACSN 11274345 11283614 12545156 14536078 15147722 15155580 15279786 17055429 17303408 17550342 17558397 17660363 17873522 18590585 18636226 20027199 20237412 20551172 20581311 20713526 20818389 21406394 21733352 2191300 21919891 22067385 23140366 23869868 25002027 28536364 7575488 9618481
MYC BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 12032322 19882681 20940401 10375022 21668996 11916966 12646176 11983916
CDK4 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 9244350 16713569 17334399 20932174
PPP1CA BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 25056273 12438214 17511879 17603999
MYC CDK4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 15208653 12835716 24951594 21384303 14519204 22395148 10688915 17728244 11983916 18414489
MYC CDK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 21988832 11602341 17093053 22094256
VCP CUL3 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 33444648 11733065 28115426 15652483 10811609 29153394
FOXO3 FOXO1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 19244250 16100571 18202312 23509296 19690465
PRKAA1 FOXO3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 17900900 17711846 22848740 29445193
MTOR MYC â—¼   ENZYMATIC_REACTION ✅ 23.0 1.0 ACSN 12150925 12408816 12906785 15755954 16469695 17604271 17680028 18372248 18492954 19022819 19446321 19568798 19706736 19864431 21157483 21981924 23087689 24795729 24973821 25002027 25730849 26159692 28216025
MYC NPM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15589822 16857742 14519204 23271972 11983916 11085504
VCP OS9 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 19002207 21357747 18502753 18711132 18264092 23867461
TUBGCP2 TUBGCP4 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 12616499 15308668 16000375 16887996 17006514 18287025 18802074 22043013 24655141 29021139
TUBGCP2 TUBGCP6 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 12616499 15308668 16000375 16887996 17006514 18287025 18802074 22043013 24655141 29021139
TUBGCP2 TUBGCP5 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 12616499 15308668 16000375 16887996 17006514 18287025 18802074 22043013 24655141 29021139
TUBGCP2 TUBGCP3 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 12616499 15308668 16000375 16887996 17006514 18287025 18802074 22043013 24655141 29021139
TUBGCP2 TUBGCP3 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 12616499 15308668 16000375 16887996 17006514 18287025 18802074 22043013 24655141 29021139
TUBGCP2 TUBGCP6 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 12616499 15308668 16000375 16887996 17006514 18287025 18802074 22043013 24655141 29021139
TUBGCP2 TUBGCP4 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 12616499 15308668 16000375 16887996 17006514 18287025 18802074 22043013 24655141 29021139
TUBGCP2 TUBGCP5 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 12616499 15308668 16000375 16887996 17006514 18287025 18802074 22043013 24655141 29021139
TUBGCP6 TUBGCP3 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 12616499 15308668 16000375 16887996 17006514 18287025 18802074 22043013 24655141 29021139
TUBGCP3 TUBGCP5 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 12616499 15308668 16000375 16887996 17006514 18287025 18802074 22043013 24655141 29021139
TUBGCP3 TUBGCP4 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 12616499 15308668 16000375 16887996 17006514 18287025 18802074 22043013 24655141 29021139
TUBGCP6 TUBGCP3 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 12616499 15308668 16000375 16887996 17006514 18287025 18802074 22043013 24655141 29021139
TUBGCP3 TUBGCP5 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 12616499 15308668 16000375 16887996 17006514 18287025 18802074 22043013 24655141 29021139
TUBGCP3 TUBGCP4 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 12616499 15308668 16000375 16887996 17006514 18287025 18802074 22043013 24655141 29021139
TUBGCP5 TUBGCP4 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 12616499 15308668 16000375 16887996 17006514 18287025 18802074 22043013 24655141 29021139
TUBGCP6 TUBGCP4 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 12616499 15308668 16000375 16887996 17006514 18287025 18802074 22043013 24655141 29021139
TUBGCP6 TUBGCP4 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 12616499 15308668 16000375 16887996 17006514 18287025 18802074 22043013 24655141 29021139
TUBGCP5 TUBGCP4 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 12616499 15308668 16000375 16887996 17006514 18287025 18802074 22043013 24655141 29021139
TUBGCP6 TUBGCP5 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 12616499 15308668 16000375 16887996 17006514 18287025 18802074 22043013 24655141 29021139
TUBGCP6 TUBGCP5 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 12616499 15308668 16000375 16887996 17006514 18287025 18802074 22043013 24655141 29021139