Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list

Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins

Filter Graph:

0.5
Layout:
  🔂

Click a node or edge for more data...

Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
HTT SAP30 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
GSK3B MAPT â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 17078951 5219283
GSK3B NFATC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12351631 9072970
CDK2 HACD3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0205180 30300385
AR OGA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21244239 20610535
RELA OGA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18397880 11395507
KAT5 AR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 10364196 5211544
HSP90AA1 AR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0908908106 19805354
AR YWHAH â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19996220 8009645
AR CARM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16492776 16344550
AR HSPA5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20610535 21125667
AR SIN3A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18945670 16254079
EZH2 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24457600 23239736
LRRK2 AURKB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
ESR1 BMI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24559156 16582100
KMT2A BMI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 25056311 19208841
EZH2 BMI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 21465172 19351856
BTRC RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16189514 9990853
CAMK2D CAMK2B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20668654 1000426
CCT2 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CCT2 RIPK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
MYC CCT3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11983916
CCT5 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CCT5 RIPK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CDK2 KAT5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 25558984 22231403
CSNK2A1 RELA â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 5212888 10938077
CSNK2A1 CSNK2B â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
LRRK2 DIDO1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
ESR1 HSPD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11085516
ESR1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 3677090
ESR1 HSPA8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11085516
MYC EZH2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21941025 19197161
EZH2 FBXO32 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 21546904 24213577
EZH2 MEN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19749796 23349306
FOXO4 FBXO32 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21798082 18701653
SP1 HDAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12847090 5216518
RELA HDAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11931769 5215238
RELA HDAC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23027620
SUMO1 HDAC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 25704882 22493095
MYC HDAC2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20697349
HSP90AA1 RIPK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSP90AA1 TAB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSP90AA1 RIPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17145710 14743216
HSPA4 TAB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPA5 RIPK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPA8 TAB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPA8 PSIP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
HSPA8 RIPK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TP53BP1 HSPD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HSPD1 OGT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
MYC HSPD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10737792
MCRS1 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
KAT5 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SUMO1 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTT S100P â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTT SNAP29 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
NUP62 KANSL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
SUMO1 KAT5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
LRRK2 LATS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
LRRK2 POU5F1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
SUMO1 MDC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
SP1 MDC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18173747
PDX1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11687580 17317781
THAP1 NUP62 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
NUP62CL OGT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
URM1 OGT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1014402108 21209336
RELA OGT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6166964 17882263
TET2 OGT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23353889
PPP1CB RIPK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
PPP1CC RIPK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
SP1 PPP1CC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9028876 12684058
SUMO1 PSIP1 â—¼   COLOCALIZATION 2.0 0.8 intact 8384636 22748127
RIPK3 PYGL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19632174 21903422
RELA TP53BP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8910340 8524315
SIN3A SUMO1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17036045 5219211
SP1 XIAP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17121920
SP1 YY1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22553354
SUMO1 TP53BP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20016603 25114211
XIAP TAB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
YY1 TP53BP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22951020
YY1 XIAP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22951020
BAP1 FOXK1 â—¼   PHYSICAL_INTERACTION 808.0 0.8 STRING 36370105
KAT8 PHF20 â—¼   PHYSICAL_INTERACTION 808.0 0.8 STRING 36370105
HCFC1 SETD1A â—¼   PHYSICAL_INTERACTION 819.0 0.81 STRING 36370105
OGT TET2 â—¼   PHYSICAL_INTERACTION 819.0 0.81 STRING 36370105
LRRK2 HACD3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31046837 24725412
HUWE1 AGR2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25147182 30575818
AGR2 S100P â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31436131 30575818
KAT5 BMI1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 27295567 16169070
BMI1 DIDO1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 34316702 24457600
MYC CXXC1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 35140242 29467282
CXXC1 MEN1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 18082152 24981860
HCFC2 DIDO1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ESR1 HUWE1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25604459 19805454
ESR1 SIN3B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 16469706 31527615
EZH2 HUWE1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 27634302 26496610
MYC RBBP4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
MYC WDR82 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
SUMO1 SIN3A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24654937 17036045
SIN3B SIN3A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 26496610
ASH2L MEN1 â—¼   PHYSICAL_INTERACTION 830.0 0.83 STRING 36370105
ASXL1 HCFC1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 26416890 32683582 27705803 32669118
FOXK2 ASXL2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 24748658 26416890 32669118 25609649 27705803
ASXL2 HCFC1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 26416890 27705803 32669118
BAP1 HCFC2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 34591877 27705803
CXXC1 BOD1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 23508102 26496610
WDR5 BOD1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 23508102 28514442 26186194 33961781
HCFC2 CXXC1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 24981860
DDAH2 HCFC1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
DPY30 MEN1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 23508102 17500065 24981860
EZH2 SIN3A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 27634302 24981860 27705803
TRAK2 FOXK1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
HDAC1 FOXK1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26496610
RBBP7 FOXK1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
THAP2 HCFC1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
KAT8 HCFC1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 16227571 20479123 24981860
MYC HCFC1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 31767764 30415952 35140242
THAP2 HCFC2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
UCHL5 MCRS1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 24981860 17721549 26186194 28514442 18922472
PHF20 MCRS1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 24981860
RBBP4 SIN3B â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 24981860 27705803
BTRC GSK3B â—¼   PHYSICAL_INTERACTION 832.0 0.83 STRING 36370105
CABIN1 HIRA â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
CARM1 RELA â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
CSNK2A1 HDAC1 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
KAT5 MYC â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
BTRC HIVEP1 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
MYC SP1 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
ASXL3 BAP1 â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
ESR1 EZH2 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 31527615 17502350
ESR1 SUMO1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 15961505 31527615
ESR1 PSPC1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 31527615 20348541
MYC HIRA â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 21150319 23602572 29467282
NUP62 THAP1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 32296183 25910212 21516116 16713569 25416956 16189514
SUMO1 PSIP1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 22748127 21110914
ASH2L HCFC2 â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
OGT PPP1CB â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
CCT3 CCT5 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
MEN1 WDR5 â—¼   PHYSICAL_INTERACTION 845.0 0.84 STRING 36370105
ESR1 ASH2L â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 16603732 21502505 31527615
ASH2L HCFC1 â—¼   PHYSICAL_INTERACTION 850.0 0.85 STRING 36370105
ESR1 RBBP5 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 16603732 21502505 31527615
ESR1 RBBP7 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 23403292 31527615 18577416 21182205
RBBP7 FOXK2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33961781 28514442 26186194 27773593
HCFC1 MEN1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 23508102 24981860 15199122
WDR5 KMT2D â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 24981860
MYC SIN3B â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 24951594 30415952
RBBP4 SP1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 12091390 16713569 12943729
BOD1L1 CXXC1 â—¼   PHYSICAL_INTERACTION 858.0 0.85 STRING 36370105
CCT2 CCT3 â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
RBBP4 DPY30 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 23995757 27705803
ESR1 MEN1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 31527615 16651450
FOXK2 HCFC1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 25609649 25451922 24748658
FOXK2 HDAC2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 25609649 27773593
HCFC2 MEN1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 23508102 24981860 15199122
WDR5 HDAC2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 28514442 27705803
MYC HUWE1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 16269333 31677785 29467282 26279298 17314511 18488021
KAT8 RBBP5 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 24981860 15960975
MEN1 RBBP5 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 17050672 24981860 14992727 23508102 15199122
HCFC1 PPP1CB â—¼   PHYSICAL_INTERACTION 861.0 0.86 STRING 36370105
TAB1 TAB3 â—¼   PHYSICAL_INTERACTION 863.0 0.86 STRING 36370105
HDAC1 YY1 â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
SAP30 FOXK1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 25609649 26496610 33961781
TRAK2 GSK3B â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 29568061 28514442 26186194 33961781
AR SP1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
WDR82 ASH2L â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 24981860 23508102 23870121 20516061 31076518
FOXK2 ASXL1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 26416890 32683582 32669118 25609649 27705803
ASXL1 FOXK1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 26416890 32683582 27705803 32669118
ASXL2 FOXK1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 26416890 32669118 26186194 27705803 28514442
ASXL2 KDM1B â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 26496610 26186194 27705803 28514442
BAP1 RBBP7 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 19615732 29686263 32509391 34591877
CXXC1 HCFC1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 23870121 26496610 24981860
DPY30 HCFC1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 22939629 24981860 23995757
ESR1 FOXK2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 25740706 31527615
FOXK2 HDAC1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 28514442 24748658 27773593
HDAC1 WDR5 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 22689669 26186194 23752268 27705803 28514442 33022573
MYC HDAC2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 22286234 17314511 30415952 20195357
WDR5 MCRS1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 24981860 15960975 27705803
MYC WDR5 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 31767764 35140242 17353931 29467282 30415952 27320920
WDR5 PHF20 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 24981860 15960975 27705803
TRAK2 TRAK1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 12435728 26186194
RBBP7 SAP30 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
HSPA4 PARK2 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
ASXL1 BAP1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
BAP1 HCFC1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
BTRC FBXW11 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
PFKL PFKM â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
RELA SP1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
SP1 YY1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
RBBP4 SAP30 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
BAP1 FOXK2 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
MCRS1 PHF20 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
PFKM PFKP â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
ESR1 HDAC1 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
CAMK2D CAMK2G â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
HDAC2 SIN3B â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
UCHL5 YY1 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
TAB1 XIAP â—¼   PHYSICAL_INTERACTION 879.0 0.87 STRING 36370105
ESR1 HSPA8 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
FOXK2 SIN3A â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 25609649 24748658 27773593
THAP1 HCFC1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 20200153 28486698
HCFC1 HCFC2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 28514442 24981860 15199122
WDR5 KANSL1 â—¼   PHYSICAL_INTERACTION ✅ 0.88 0.88 mint 24981860
SP1 SUMO1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 18239466 18572193
ESR1 HSPA4 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
LRRK2 YWHAH â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
HDAC2 RELA â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
HSPA4 MAPT â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
HDAC2 SAP30 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
PPP1CB PPP1CC â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
AR HSP90AA1 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
HSPA8 MAPT â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
CXXC1 DPY30 â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
PPP1CC URI1 â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
CSNK2A1 HDAC2 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
DPY30 SETD1B â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
ESR1 HSP90AA1 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
HDAC2 YY1 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
HSPA8 LRRK2 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
SAP30 FOXK2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 25609649 26496610 33961781 27773593
MYC GSK3B â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 16247449 20713710 19131971 21150319 31638140 29467282 11877389 33541412 14563837 8247524
MEN1 ASH2L â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 17050672 24981860 14992727 23508102 15199122
DISC1 PSPC1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 29961565 31413325 32296183
HDAC2 SP1 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
WDR5 KAT8 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 20479123 24981860 15960975 27705803
MEN1 PSIP1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 22327296 18598942 23508102
WDR82 RBBP5 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 24981860 23508102 23870121 20516061 31076518
TAB3 TAB1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 14670075 27880917 21903422 18021073
HIRA UBN1 â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
RBBP4 RBBP7 â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
HDAC1 RELA â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
EZH2 HDAC2 â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
BMI1 PHC3 â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
KMT2A MEN1 â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
RBBP4 SIN3A â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
SAP30 RBBP7 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 10444591 33961781 9651585 9790534 11283269 26496610 15451426 26186194 11784859 27705803 28514442
KIF5B GSK3B â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
OGA GSK3B â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
FIBP GSK3B â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
MYC GSK3B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
AR GSK3B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20127713 20610535 18687691
GSK3B AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15361837 15178691 14985354
OGA CSNK2B â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
KAT5 OGA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17360565 18458078 15988028
AR SUMO1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24119295 21796528 17932034
RELA AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 16713569 8798655
CXXC1 ASH2L â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 20305087 19410543 24981860 23870121 26496610 23508102 34079125 19433449 18680430 28514442 18082152 31076518 16253997
BAP1 ASXL1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 23850490 34591877 33961781 26437366 20805357 22897849 19615732 26416890 26739236 34170818 32683582 19815555 32669118 21642991 33758188 27705803 20436459
BAP1 ASXL2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 33731362 34591877 20805357 19615732 26416890 32669118 26186194 27705803 19815555 28514442 29284740
PPP1CC CAMK2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 8753794 9109540 12928489
CAMK2G HDAC5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11114197
MYC CCT5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
CDK2 SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11598016 19450264
MYC CEACAM5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
SP1 CSNK2A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10849443 19027835
MYC CXXC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
MYC DPY30 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
ESR1 SUMO1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15961505 24119295 18404132
HCFC1 SP1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 12670868 16713569 10976766
YY1 HCFC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8661027 23000143
SIN3A HDAC1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 12724404 24981860 14593184 26496610 11102443 17827154 10220385 14647463 9885572 15695521 12398767 26344197 21258344 9804427 16331260 12091390 9150133 11602581 10640275 12920132 9790534 17643391 12943729 19182791 25314079 12374985 28514442 26949739 10444591 11931768 11171972 17956988 12453419 15451426 23752268 11784859 18059533 20585571 9520398 11118440 17962807
MYC HDAC1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 34147029 22286234 26496610 30415952 18271930 17314511 18003922 24951594
HDAC1 YY1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18634613 11486036 11940654
UBN1 HIRA â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 22401310 33961781 24981860 19029251 22195966 23602572 27217568 21807893
MYC HSP90AA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 28914785 12644583
MYC HSPA8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11983916 12695333
SP1 HTT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22399227 20018729
MYC MEN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
YY1 MYC â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 18490439 19219071 2191300
MYC RBBP4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
RELA MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12027803 16713569
MYC SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11274368 16713569
TET3 OGT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23222540 23353889
SIN3A RBBP4 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 9651585 11602581 24981860 21258344 12453419 15451426 9150133 12943729 27705803 9150135 11118440
SIN3A RBBP7 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 17255935 9651585 24981860 12453419 15451426 26186194 11784859 27705803 28514442
YY1 WDR82 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22951020
ESR1 SP1 â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
HSP90AA1 HSPA4 â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
RBBP7 SIN3A â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
HDAC1 SAP30 â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
HDAC1 SUDS3 â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
RBBP5 WDR82 â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
CSNK2A1 OGT â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
RBBP7 SIN3B â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
CXXC1 WDR5 â—¼   PHYSICAL_INTERACTION 907.0 0.9 STRING 36370105
SAP30 SIN3A â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
KMT2D RBBP5 â—¼   PHYSICAL_INTERACTION 911.0 0.91 STRING 36370105
HSPA4 HSPA8 â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
KANSL1 KAT8 â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
KANSL1 PHF20 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
DPY30 KMT2A â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
PPP1CC WDR82 â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
HSP90AA1 LRRK2 â—¼   PHYSICAL_INTERACTION 919.0 0.91 STRING 36370105
ASH2L KMT2D â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
HDAC1 SP1 â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
CXXC1 WDR82 â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
PPP1CB WDR82 â—¼   PHYSICAL_INTERACTION 923.0 0.92 STRING 36370105
HCFC2 WDR5 â—¼   PHYSICAL_INTERACTION 925.0 0.92 STRING 36370105
DPY30 SETD1A â—¼   PHYSICAL_INTERACTION 929.0 0.92 STRING 36370105
HSP90AA1 HSPA8 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
EZH2 RBBP7 â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
EZH2 HDAC1 â—¼   PHYSICAL_INTERACTION 939.0 0.93 STRING 36370105
WDR82 WDR5 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 20516061 23870121 27705803
CXXC1 SETD1B â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
KMT2A PSIP1 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
SETD1B WDR82 â—¼   PHYSICAL_INTERACTION 942.0 0.94 STRING 36370105
EZH2 RBBP4 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
KANSL2 WDR5 â—¼   PHYSICAL_INTERACTION 949.0 0.94 STRING 36370105
CXXC1 SETD1A â—¼   PHYSICAL_INTERACTION 950.0 0.95 STRING 36370105
WDR5 KMT2A â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 24981860
MDC1 TP53BP1 â—¼   PHYSICAL_INTERACTION 951.0 0.95 STRING 36370105
WDR5 WDR82 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
KAT8 WDR5 â—¼   PHYSICAL_INTERACTION 953.0 0.95 STRING 36370105
CCT2 CCT5 â—¼   CORRELATES + 0.95 0.95 CCLE 31978347
SIN3B SUDS3 â—¼   PHYSICAL_INTERACTION 954.0 0.95 STRING 36370105
CAMK2A CAMK2B â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
CXXC1 RBBP5 â—¼   PHYSICAL_INTERACTION 959.0 0.95 STRING 36370105
DPY30 ASH2L â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 8153045 21516116
CAMK2B CAMK2D â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
HDAC1 SIN3B â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
ASH2L CXXC1 â—¼   PHYSICAL_INTERACTION 964.0 0.96 STRING 36370105
CAMK2A CAMK2D â—¼   PHYSICAL_INTERACTION 969.0 0.96 STRING 36370105
HCFC1 WDR5 â—¼   PHYSICAL_INTERACTION 969.0 0.96 STRING 36370105
HDAC2 RBBP4 â—¼   PHYSICAL_INTERACTION 969.0 0.96 STRING 36370105
SIN3A SAP30 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 10444591 12724404 33961781 9651585 11118440 24981860 21258344 9790534 11283269 26496610 12453419 15451426 11784859 16820529 21676866 11390640 9702189
SAP30 HDAC1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 26496610 11390640 9885572 9651585 15235594 21258344 12788099 16713569 9790534 11283269 16820529 28514442 18193082 10444591 15451426 23752268 11784859 11118440
SAP30 RBBP4 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 10444591 33961781 9651585 24981860 9790534 11283269 15451426 16713569 11784859 27705803
RBBP4 HDAC1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 21670149 24981860 22939629 26496610 34518534 11302704 11102443 27705803 17827154 10734134 10220385 9885572 10471499 26344197 21258344 12091390 9150133 16713569 11602581 12920132 20127688 9790534 17643391 11470869 19686092 12943729 9150135 28514442 16189514 27068747 10444591 19703393 11171972 15451426 23752268 20585571 9520398 11118440 31435636
RBBP7 HDAC1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 17255935 22939629 26496610 11102443 27705803 9885572 10471499 26344197 21258344 12920132 9790534 19686092 9150135 28514442 25885317 10444591 19703393 15451426 26186194 23752268
HDAC2 HDAC1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 21670149 24981860 22939629 26496610 11102443 11919195 11777905 30737378 9885572 22416134 26344197 21258344 9804427 12493763 11287668 16713569 11466315 12920132 20388487 9790534 10581039 11739383 15987735 17894944 19182791 9150135 28514442 26949739 19041848 10444591 19703393 11804585 25241761 17956988 11564889 12032298 15451426 15297431 23752268 18059533 9520398
SIN3A HDAC2 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 12724404 16254079 12082111 24981860 17827154 22493095 9885572 12398767 26344197 21258344 9804427 12493763 14749338 12091390 12943729 25314079 26949739 12453419 15451426 23752268 9150134 18059533
SETD1A WDR82 â—¼   PHYSICAL_INTERACTION 970.0 0.97 STRING 36370105
ASH2L SETD1B â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
ASH2L WDR82 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
RBBP5 SETD1B â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
HDAC1 RBBP7 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
HDAC2 RBBP7 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
ASH2L SETD1A â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
HCFC1 OGT â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
RBBP5 SETD1A â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
CSNK2B CSNK2A1 â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 36833176
DPY30 WDR5 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
ASH2L KMT2A â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
KMT2A WDR5 â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
KMT2A RBBP5 â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
SIN3A SUDS3 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
KANSL1 KANSL2 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
ASXL2 BAP1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
KANSL1 WDR5 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
HDAC1 RBBP4 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
SETD1A WDR5 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
SETD1B WDR5 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
GSK3B MAPT â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
DPY30 RBBP5 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
KMT2D WDR5 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RBBP5 WDR5 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
CCT2 CCT3 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT2 CCT5 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT3 CCT5 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CSNK2A1 CSNK2B â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
GSK3B ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 10428798 10949034 17609434 15461668 9528769 12118371 15059947 16076840 17570479 7491495 12093745 8308015 15212693 15528270 7838153
GSK3B MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 73.0 1.0 Omnipath 17081983 18463697 21646472 30037819 26751215 25647305 2663470 20080742 19797085 30003124 16855632 12040186 18679417 11018017 23331499 29229669 16611981 21071413 24265759 20068231 10671551 16039586 17570479 16023596 29258530 12615961 18669648 21113395 22461507 19131971 8247524 16247449 20604938 19575820 15150404 22481935 23668310 19651622 17444818 23964270 20537194 22893788 27684546 24662831 25333250 20399964 11877389 14563837 18408012 17052453 18455992 15212693 16371461 11274345
GSK3B PDX1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 16407209 19833727
GSK3B KLF5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 24398687 20484041 28480051
GSK3B RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 18201972 15465828 15280197 22761446 20537194 21194439 19345186 21660967 19997086 16407239 25629551 17183360
GSK3B MAPT â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 141.0 1.0 Omnipath 19616957 22278060 25641096 9832145 19562805 12387894 24268883 9546672 31640277 21865886 19413330 28386764 28379300 1330687 28734998 19415658 15302935 17047304 7706316 27349344 29408874 9716264 9353289 21671254 24165324 12714590 20068231 12387897 17570479 16452634 25815351 21215781 16568235 16519507 8999860 17045592 9565682 27857758 11181841 14690523 22690349 27073700 21443865 10601262 7566346 10737616 15522877 12435421 17287340 9771888 29725295 15073173 17078951 19651622 1181841 15542598 9735171 12226093 11104762 21985244 20049527 28835279 27965573 20679343 20308788 9199504 18510355 10090741 11311121 2387894
GSK3B KAT5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 22539723 17570479 21658600
GSK3B NFE2L1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 23623971
SP1 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 8864062 16928829 16704988 23662037 10773882 9353275 15661808 17984071 18430409 22347450 20739403 8994183
RELA AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 24466341 16619263 14576180 15517885 14715080
ESR1 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8299561 11000528 22391641
AR KLF5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19460858 20610535
KAT5 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 11591700 10364196 19150978 11994312 16713569
HDAC1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 11994312 16713569 15640443 12612053 10428808
HSP90AA1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 1525041 19805354 20048054 15861399 17974989 26342197 17353003 26196320 16713569 27903893 1540595 21157430 19706771
AR ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 12389206 11032808 16713569 11000528 18988627
ASH2L WDR5 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
ASH2L RBBP5 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
ASH2L DPY30 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
ASH2L WDR5 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
ASH2L DPY30 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
ASH2L RBBP5 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
EZH2 ASXL3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19934320 18687996 24771265 24132643
AURKB YY1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23226345
AURKB TP53BP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 28415769
AURKB HDAC5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 22865920
MYC BMI1 â—¼   UP_REGULATES ✅ + 32.0 1.0 ACSN 11274345 11283614 12545156 14536078 15147722 15155580 15279786 17055429 17303408 17550342 17558397 17660363 17873522 18590585 18636226 20027199 20237412 20551172 20581311 20713526 20818389 21406394 21733352 2191300 21919891 22067385 23140366 23869868 25002027 28536364 7575488 9618481
HDAC1 BMI1 â—¼   UP_REGULATES ✅ + 22.0 1.0 ACSN 11283614 12545156 12668723 15151915 15155580 15465827 16232121 17055429 17508028 17550342 20027199 20713526 20818389 21234400 21733352 2191300 21919891 22370643 22796940 23140366 23869868 9618481
CDK2 BMI1 â—¼   UP_REGULATES ✅ + 32.0 1.0 ACSN 11274345 11283614 12545156 14536078 15147722 15155580 15279786 17055429 17303408 17550342 17558397 17660363 17873522 18590585 18636226 20027199 20237412 20551172 20581311 20713526 20818389 21406394 21733352 2191300 21919891 22067385 23140366 23869868 25002027 28536364 7575488 9618481
RELA BTRC â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 9990852 10514433 9859996 9990853 7628694
UBN1 CABIN1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 19029251 15621527 21807893 17242207 17242198
HIRA CABIN1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 19029251 15621527 21807893 17242207 17242198
CAMK2A MAPT â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 30.0 1.0 Omnipath 7706316 9735171 9832145 12387894 10737616 12435421 9771888 15621017 10090741 8999860
ESR1 CARM1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 14631847 12498683 11010967 14675539
RELA CD40 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11313274 17031478 19164127 9733827 10075983
NFATC1 CD40 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 21913318 21413932 19801646 23990468 20831919
MYC CDK2 â—¼   PHYSICAL_INTERACTION 34.0 1.0 ACSN 11274345 11283614 12545156 14536078 15147722 15155580 15279786 17055429 17303408 17550342 17558397 17660363 17873522 18590585 18636226 19887899 20027199 20237412 20551172 20581311 20713526 20818389 21406394 21733352 2191300 21919891 22067385 23140366 23869868 24954210 25002027 28536364 7575488 9618481
MYC CDK2 â—¼   SHARES_COMPLEX 34.0 1.0 ACSN 11274345 11283614 12545156 14536078 15147722 15155580 15279786 17055429 17303408 17550342 17558397 17660363 17873522 18590585 18636226 19887899 20027199 20237412 20551172 20581311 20713526 20818389 21406394 21733352 2191300 21919891 22067385 23140366 23869868 24954210 25002027 28536364 7575488 9618481
CDK2 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 10428798 22431515 23390529 17570479 23770852
CDK2 FOXK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20810654
CDK2 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 8386367 27653698 17081983 19966300 18669648 29896817 17570479 20713526 17558397 15103331 22348395 20445224
CDK2 EZH2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 20935635 25800736 29576612 23241245 32368395 29556394 17570479 27863310 26279746
CDK2 HIRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 20068231 11238922 19413330
CSNK2A1 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 34049972 15016307 10938077 27630163
CSNK2A1 HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 19651622 19415658 17081983 20166139 18767875 11602581 20068231 18452278 17287340 19413330 22113938 18669648
CSNK2A1 YY1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22184066 23226345
CSNK2A1 HDAC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 32.0 1.0 Omnipath 19007248 16565220 20166139 17081983 20230923 25609639 19413330 19415658 20388487 20068231 18452278 18669648 18691976 17287340 12176973 19651622 12082111 19691289 24526703 18510355 18212344
CSNK2A1 MDC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 20711462 20507565 19118383 18411308 21576760 18678890 18583988 15066279 20471329 19230643 21592330 21118972 18006705 20533398
CSNK2A1 SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 9153193
CSNK2A1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 11139588 26703694 9337862 20043841 11432835 11507039 9528769 7838153
RBBP5 DPY30 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
WDR5 DPY30 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
RBBP5 DPY30 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
WDR5 DPY30 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
SP1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 12237165 19351845 11345900 21235772 23209644 12429135 18006846 10982795 22622808 15691879 21191649
HDAC1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 21655924 23242655 18316616 20101232
ESR1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 22396492 21835891 15073177 18193094 11517191 21505052 22892083 8707895 19569049 14722073 18414489
KMT2D ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17145710 16603732
HDAC1 EZH2 â—¼   PHYSICAL_INTERACTION 8.0 1.0 ACSN 15465827 17018611 17563753 21234400 21577210 21685935 22514743 22796940
HDAC2 EZH2 â—¼   PHYSICAL_INTERACTION 8.0 1.0 ACSN 15465827 17018611 17563753 21234400 21577210 21685935 22514743 22796940
HDAC2 EZH2 â—¼   SHARES_COMPLEX 8.0 1.0 ACSN 15465827 17018611 17563753 21234400 21577210 21685935 22514743 22796940
HDAC1 EZH2 â—¼   SHARES_COMPLEX 8.0 1.0 ACSN 15465827 17018611 17563753 21234400 21577210 21685935 22514743 22796940
RELA FBXW11 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 10321728 9990852 10066435 9859996 10514424 10230406
SUMO1 HDAC1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11960997 12032081 15199155 24068740
HDAC1 HDAC2 â—¼   PHYSICAL_INTERACTION 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 SIN3A â—¼   PHYSICAL_INTERACTION 27.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 HDAC2 â—¼   SHARES_COMPLEX 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 SIN3A â—¼   SHARES_COMPLEX 27.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 HDAC2 â—¼   UP_REGULATES ✅ + 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 SIN3A â—¼   UP_REGULATES ✅ + 27.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 11564889 11931769 16483679 30670829 16325585 16713569 17183360 21983014
HDAC1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 21734722 17666529 15576399 22761862 22290435 19923891 20682799
HDAC2 SIN3A â—¼   PHYSICAL_INTERACTION 8.0 1.0 ACSN 14673164 15465827 17018611 17563753 21234400 21577210 22514743 22796940
HDAC2 SIN3A â—¼   SHARES_COMPLEX 8.0 1.0 ACSN 14673164 15465827 17018611 17563753 21234400 21577210 22514743 22796940
HDAC2 YY1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 9016636 19139378 11486036 8917507
SP1 HSPA4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 7553870 9060426 2674689 24669866
MYC HSPA4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 1534087 14519204 1562593 10446203
YY1 HSPA5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 16452489 15899857 15760841 8972185
MYC HSPD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 19022255 12695333 14519204 21995449 11983916 11085504
HUWE1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 26279298 16915296 34761308 16969074
KAT5 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12776177 19150978 15572685 34650217
KMT2A KAT8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15960975
MEN1 KMT2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 17145710 15199122 19075677 16618927 17671196 22936661 22327296 15640349 16997566 20818375 20961854
KMT2A MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20677832 16510874
LRRK2 MAPT â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 22924508 24113872 26123245 24165324 25977830 22303461
MDC1 TP53BP1 â—¼   DOWN_REGULATES ✅ - 13.0 1.0 ACSN 12607003 15279786 15459660 17303408 17660363 18001824 18006705 18087291 18583988 18590585 18678890 7575488 9407949
MDC1 TP53BP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16009723 17145710 18087291 17925396 12607005
MEN1 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 11526476 14508515 16713569
SP1 MKI67 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21611785 22890831 22125028 20963645
MYC PFKM â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 ACSN 11274345 11283613 11283614 11704864 15199147 17055429 17558397 17873522 20027199 20237412 20551172 20581311 20713526 21406394 2191300 22067385 25002027 28536364
YY1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 9797456 16314465 10528225 8266081 19279113 17287852 10713181 18490439 17434929 16878156 18542060
SP1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11470523 9492315 2284094 8437848 7753559 8355712 2057364
RELA MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 12894581 18184402 7869034 17673602 12783888 11114727 17944672 9596659 19469019 21790895 19766095 17018379 8289784 18566231
MYC PFKM â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10823814 11983916
YY1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8266081 15805285 18490439 19219071 2191300
RIPK3 PYGL â—¼   PHYSICAL_INTERACTION 31.0 1.0 ACSN 11274345 16469705 17603935 18641653 19037093 19498109 19524512 19524513 19632174 20823910 20861672 21133840 21232017 22265414 22421439 23010170 23073834 23627914 24366341 26024392 26587781 26653790 26807733 26853145 26900751 27558815 27833036 27959630 28498367 28574505 28645028
RIPK3 PYGL â—¼   SHARES_COMPLEX 31.0 1.0 ACSN 11274345 16469705 17603935 18641653 19037093 19498109 19524512 19524513 19632174 20823910 20861672 21133840 21232017 22265414 22421439 23010170 23073834 23627914 24366341 26024392 26587781 26653790 26807733 26853145 26900751 27558815 27833036 27959630 28498367 28574505 28645028
WDR5 RBBP5 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
WDR5 RBBP5 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
SP1 RELA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 7636984 8450395 9151857 20538607 11964305
RELA XIAP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 15041463 18223231 14739605 16157589 18978816 18761050 15756023 18566231 16453001
RELA SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12055073 7933095 10671503 20861353
XIAP TAB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 9878061 12048196 17560374 27107012 11865055 23818254
DDB2 OGT â—¼   KO_DOWN_REGULATES ✅ - -1.02 1.01 PKG 28854368
DDB2 DIDO1 â—¼   KO_DOWN_REGULATES ✅ - -1.08 1.07 PKG 28854368
MDC1 DIDO1 â—¼   KO_UP_REGULATES ✅ + 1.24 1.24 PKG 28854368
MDC1 MDC1 â—¼   KO_DOWN_REGULATES ✅ - -3.38 3.37 PKG 28854368
DDB2 DDB2 â—¼   KO_DOWN_REGULATES ✅ - -5.71 5.7 PKG 28854368
TP53BP1 TP53BP1 â—¼   KO_DOWN_REGULATES ✅ - -9.54 9.53 PKG 28854368