Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
YY1 ACTA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21169469 23705901
TP53 ACTA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17409411
CXXC1 BDNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21765426 20410295
PTEN CXXC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
SMARCA2 CXXC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
CXXC1 TBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
DNMT1 PTEN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19339266 21229291
TP53 DNMT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18431400
EP300 RB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16374512 11433299
HNF4A TBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19805548
MYC HSP90AB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11983916
IGFBP3 YWHAG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
KLF2 RELN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21530336
MYB MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15082531
RB1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 7838535
POMC OPRM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 7905839 8208289
TP53 PPP1CA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
TP53 RB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
RB1 TBP â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11094070 16713569
YWHAG VIM â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
ASH2L HIST2H4A â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
ASH2L HIST2H3C â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
DPY30 HIST2H4A â—¼   PHYSICAL_INTERACTION 804.0 0.8 STRING 36370105
DPY30 HIST2H3C â—¼   PHYSICAL_INTERACTION 804.0 0.8 STRING 36370105
HIST2H4A RBBP5 â—¼   PHYSICAL_INTERACTION 806.0 0.8 STRING 36370105
KLF2 EP300 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 15136591 21482710
HIST2H3C RBBP5 â—¼   PHYSICAL_INTERACTION 812.0 0.81 STRING 36370105
HCFC1 SETD1A â—¼   PHYSICAL_INTERACTION 819.0 0.81 STRING 36370105
CXXC1 MLL2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 18082152 24981860
HIST2H4A WDR5 â—¼   PHYSICAL_INTERACTION 820.0 0.82 STRING 36370105
MK BD1L1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
MK E41L5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
MK SET1A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
MK CXXC1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RING2 CXXC1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26496610 24457600
HCFC2 OGT1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CXXC1 H4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30804502 18082152
PESC SET1A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
KCC2D SET1A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RSBN1 SET1A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
E41L5 SET1A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
MYC SET1A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 35140242 29467282
SET1A ELF2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 35140242 31076518
PI42A SET1B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SET1B DPY30 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26496610 24981860
MYC KCC2D â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21150319 29467282
KCC2D CXXC1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
KCC2D BD1L1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ZN408 CXXC1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
PI42A CXXC1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
PI42A E41L5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
PESC CXXC1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
MYC PESC â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
E41L5 BD1L1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
E41L5 CXXC1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
MYC CXXC1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 35140242 29467282
RSBN1 CXXC1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CXXC1 MEN1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 18082152 24981860
MYC DNMT1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
MYC WDR82 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
MYC RBM15 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26496610 29467282
HIST2H4A WDR77 â—¼   PHYSICAL_INTERACTION 823.0 0.82 STRING 36370105
HIST2H4A KMT2A â—¼   PHYSICAL_INTERACTION 827.0 0.82 STRING 36370105
PPP1CA RB1 â—¼   PHYSICAL_INTERACTION 828.0 0.82 STRING 36370105
HIST2H3C KMT2A â—¼   PHYSICAL_INTERACTION 829.0 0.82 STRING 36370105
PRS6A ELF2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
PRS6A CXXC1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
ANM2 CXXC1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
ANM2 SET1B â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
ANM2 SET1A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
HCFC2 SET1A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 24981860
EDA SET1A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
NUP50 SET1A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
BD1L1 SET1A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 26496610 24981860 31076518
WDR82 SET1B â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 20516061 23870121 27563068 17355966
BD1L1 CXXC1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 24981860 23508102 26496610 28514442
BD1L1 RBBP5 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 24981860 23508102 26496610 31076518
HCFC2 BD1L1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 24981860
ASH2L MEN1 â—¼   PHYSICAL_INTERACTION 830.0 0.83 STRING 36370105
CXXC1 BOD1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 23508102 26496610
WDR5 BOD1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 23508102 28514442 26186194 33961781
EDA CXXC1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
NUP50 CXXC1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
PRPS1 CXXC1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
HCFC2 CXXC1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 24981860
DPY30 MEN1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 23508102 17500065 24981860
PRPS1 ELF2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
MYC HCFC1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 31767764 30415952 35140242
MYC NONO â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 21150319 29467282 17314511 17967896
HIST2H3C WDR5 â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
P53 BAG6 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 31647545 22653443
KCC2D OGT1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 28514442 32707033
OGT1 WDR5 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 23353889 27705803
EP300 WDR82 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 23870121 33742100
ASH2L HCFC2 â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
BAK1 TP53 â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
HIST2H3C HIST2H4A â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
MEN1 WDR5 â—¼   PHYSICAL_INTERACTION 845.0 0.84 STRING 36370105
P53 RBBP5 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 23870121 15960975 19433796
OGT1 CXXC1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 23508102 23353889 27705803
OGT1 SET1A â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 31076518 29474905 23353889 27705803
OGT1 RBBP5 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 31076518 23508102 23353889 27705803
SET1A DPY30 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 24981860 23870121 17500065 23453808 31076518
ASH2L HCFC1 â—¼   PHYSICAL_INTERACTION 850.0 0.85 STRING 36370105
HCFC1 MEN1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 23508102 24981860 15199122
WDR5 KMT2D â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 24981860
KMT2A MYB â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
PTEN TP53 â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
BOD1L1 CXXC1 â—¼   PHYSICAL_INTERACTION 858.0 0.85 STRING 36370105
EP300 H4 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 11691934 14752096 23587423 16717280 25728767 12499368 11689448 18397880 30804502 11830591 16096645 11884585 14585496 30902546 15611041 16287840 15308690 10607594 28465257 26625199 15834423 11983172 8945521 11163245 22100137 28844863 11689053 16415179 18418072 15136563 16109717 23934153 15951563 20368990 14612423 17982102 12237408 16332960
H4 DNMT1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 30804502 30021884
HCFC2 MEN1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 23508102 24981860 15199122
MEN1 RBBP5 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 17050672 24981860 14992727 23508102 15199122
MYC TBP â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 15723054 16713569 8755740
PTEN P53 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 24141722 12620407 16713569 14559824 18339852
MYC PRS6A â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 21988832 17314511 29467282
HCFC1 SET1A â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 24981860 27563068 12670868 17998332 31076518
NUP50 BD1L1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 26186194 34079125
WDR5 BD1L1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 24981860 26186194 27705803 28514442
WDR82 ASH2L â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 24981860 23508102 23870121 20516061 31076518
CXXC1 HCFC1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 23870121 26496610 24981860
DPY30 HCFC1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 22939629 24981860 23995757
MYC EP300 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 12776737 16287840 32140074 15616592 16126174 17157259
NUP50 KIFC1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 26186194 34079125
MYC WDR5 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 31767764 35140242 17353931 29467282 30415952 27320920
MLL2 H4 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 30604749 30804502 31127101
SET1A P53 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 23870121 29474905 31076518
CXXC1 P53 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 23870121 32807901
P53 ASH2L â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 23870121 19433796
OGT1 ASH2L â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 23508102 27705803 23353889 31076518 34079125
SET1A WDR82 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 24981860 17355966 27563068 23870121 17998332 20516061 29474905 31076518
SET1B ASH2L â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 20305087 24981860 27563068 23508102 17998332 26496610 26886794 34079125
HCFC1 HCFC2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 28514442 24981860 15199122
TBP TP53 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
EP300 YY1 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
RNF2 WDR5 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
CXXC1 DPY30 â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
DPY30 SETD1B â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
HSP90AA1 HSP90AB1 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
MYC P53 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 21150319 30415952 28205554 28628118
SET1B RBBP5 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 24981860 17355966 27563068 23508102 26496610 29785026 20516061 31076518
MEN1 ASH2L â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 17050672 24981860 14992727 23508102 15199122
NFYC MYC â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10446203 11282029
WDR82 RBBP5 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 24981860 23508102 23870121 20516061 31076518
KRT75 VIM â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
KMT2A MEN1 â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
PPP1CA PPP1CC â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
WDR5 MLL2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 24788516 33961781 17178841 24981860 15960974 16603732 24491801 27705803 22665483 33022573 27563068 30604749 15960975 22689669 28514442 32350066 17500065 26186194 17925232 30107592 22266653
TP53 CCNA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17530187 15456866
MYB CCNA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10590070
HNF4A P53 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 35140242 11818510 16713569 28514442
TBP P53 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 7799929 8083962 1465435 12379483 10601022 16713569 11313951 8395834 8405994 9349482 10359315
EP300 P53 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 29706626 25156994 12724314 23728348 16543236 12501250 9652736 9194564 18243116 9194565 19339993 16678111 16611888 11359905 11782467 12162806 14612423 14759370 15186775 15664194 9288740 23402884 17452980 24157709 9891054 12499368 19234109 27818144 16537920 17977830 15295102 10518217 16713569 26625199 16928824 11070080 17906639 23870121 23796514 15558054 17438265 25867071 17189186 18485870 11907332 15542844 19217391 32807901 16438982 31167125 15337767 10490106 22731250 12690203 25288747 18612383 23329847 24821727 26302407 9809062 16959611 22074660 19218448 16782091 23880760 33196849 25753752 28757384 18391200 16024799 25651062 16135789 22013068 11433299 9744860 10601022 21187340 11804596 23307557 10942770 15509808 20234175 21471221 26229107 19805293 22266186 15965232 23010591
OGT1 HCFC1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 21285374 20200153 12670868 22939629 21295698 32994395 27705803
CXXC1 SET1A â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 19951360 19410543 33961781 24981860 17355966 27563068 23870121 17998332 26496610 23508102 19433449 23453808 18680430 28514442 29474905 18082152 31076518 16253997
SET1A ASH2L â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 20305087 21653943 24981860 27563068 22939629 17998332 23870121 23508102 26886794 34079125 23453808 29474905 31076518 16253997
SET1A RBBP5 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 20305087 21653943 24981860 17355966 27563068 22147691 17998332 22939629 23870121 23508102 29785026 23453808 20516061 29474905 31076518 16253997
WDR5 SET1A â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 20305087 33022573 29474905 15960975 17355966 24981860 27563068 23870121 26186194 23453808 27705803 28514442 22665483 22266653 31076518 16253997
SET1B WDR5 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 33022573 24981860 17355966 27563068 26496610 26186194 27705803 28514442 22665483 22266653
CXXC1 SET1B â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 24981860 17355966 27563068 23870121 22939629 26496610 23508102 19433449 18680430 28514442
CXXC1 ASH2L â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 20305087 19410543 24981860 23870121 26496610 23508102 34079125 19433449 18680430 28514442 18082152 31076518 16253997
TP53 BAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16713569 15077116
MYC CXXC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
DNMT1 MT1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16329111 22905112 12417732
MYC DPY30 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
YY1 EP300 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22951020
YY1 HCFC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8661027 23000143
HNF4A NOS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17317687 11741883 16479620
HNF4A VIM â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16568083 12750294 19671543
HSP90AA1 TP53 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
MYC HSP90AA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 28914785 12644583
MYC MEN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
YY1 MYC â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 18490439 19219071 2191300
RB1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 7680889 10200487 9671466
YY1 NOS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 19402223 20430007
TBP RB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9242374 10197586 9400991
YY1 WDR82 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22951020
EP300 MYB â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
RBBP5 WDR82 â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
MEOX2 WDR5 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
CXXC1 WDR5 â—¼   PHYSICAL_INTERACTION 907.0 0.9 STRING 36370105
KMT2D RBBP5 â—¼   PHYSICAL_INTERACTION 911.0 0.91 STRING 36370105
DPY30 KMT2A â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
PPP1CC WDR82 â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
EP300 TP53 â—¼   POLYUBIQUITINATION ✅ - 0.91 0.91 Signor 12690203
ASH2L KMT2D â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
CXXC1 WDR82 â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
HCFC2 WDR5 â—¼   PHYSICAL_INTERACTION 925.0 0.92 STRING 36370105
DPY30 SETD1A â—¼   PHYSICAL_INTERACTION 929.0 0.92 STRING 36370105
PPP1CA WDR82 â—¼   PHYSICAL_INTERACTION 934.0 0.93 STRING 36370105
WDR5 RING2 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 33961781 24981860 15960975 26186194 27705803 28514442 22325352
WDR82 WDR5 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 20516061 23870121 27705803
CXXC1 SETD1B â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
SETD1B WDR82 â—¼   PHYSICAL_INTERACTION 942.0 0.94 STRING 36370105
CXXC1 SETD1A â—¼   PHYSICAL_INTERACTION 950.0 0.95 STRING 36370105
WDR5 KMT2A â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 24981860
WDR5 WDR82 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
CXXC1 RBBP5 â—¼   PHYSICAL_INTERACTION 959.0 0.95 STRING 36370105
DPY30 ASH2L â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 8153045 21516116
ASH2L CXXC1 â—¼   PHYSICAL_INTERACTION 964.0 0.96 STRING 36370105
HCFC1 WDR5 â—¼   PHYSICAL_INTERACTION 969.0 0.96 STRING 36370105
SETD1A WDR82 â—¼   PHYSICAL_INTERACTION 970.0 0.97 STRING 36370105
ASH2L SETD1B â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
ASH2L WDR82 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
RBBP5 SETD1B â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
ASH2L SETD1A â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
HCFC1 OGT â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
RBBP5 SETD1A â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
DNMT1 RB1 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
TP53 EP300 â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 16611888 6599495
DPY30 WDR5 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
ASH2L KMT2A â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
KMT2A WDR5 â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
KMT2A RBBP5 â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
SETD1A WDR5 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
SETD1B WDR5 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
DPY30 RBBP5 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
KMT2D WDR5 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RBBP5 WDR5 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
EP300 TP53 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
DYRK2 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 111.0 1.0 Omnipath 29296831 21383696 14749479 11740489 20171273 25778922 15843377 33906076 10581258 15750624 15897882 15706352 26236013 24899407 33572115 17906639 20935676 24379358 17386256 15870257 26346493 12427754 34103685 17567906 11101524 17210684 18536714 15381073 19965871 26578795 26087959 28060750 21765464 20673369 34216619 16601678 17380123 33443163 18216278 21642861 15526030 22878263 17349959 16738336 20696760 19882354 16219768 17105820 16793543 17332358 24901999 16247456 24196445 26804244 15657359 27208501 18056705 21765463 23420876 22797063 16377624 19861417 18160537 12676607 20123963 15489221 17591690 20514025 23149944 19857493 17891183 27034505 11780126 21057547 25944899 26341817 17349958 20962272 22525275 19828042 12902982 19465479 15471885 15322239 11495913 12907596 32083004 25915850 20018442 24145406 26029824 21394211 12093737 33872315 20610713 20024960 26113041 20811699 18560558 21660965 16717128 11030628 17107963
MLL2 ASH2L â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
MLL2 RBBP5 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
MLL2 RBBP5 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
MLL2 ASH2L â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
MLL2 DPY30 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
MLL2 WDR5 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
MLL2 DPY30 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
MLL2 WDR5 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
CCNA1 RB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 7575488 18590585 17303408 10022926 16189514 17660363 15279786
ASH2L WDR5 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
ASH2L RBBP5 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
ASH2L DPY30 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
ASH2L WDR5 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
ASH2L DPY30 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
ASH2L RBBP5 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
TP53 BAK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 22983126 18519674 21233848 15033822 15489892 15105295 10741712
RBBP5 DPY30 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
WDR5 DPY30 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
RBBP5 DPY30 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
WDR5 DPY30 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
EP300 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 17145710 22290435 19623618 11804596 23343194 22761862 16039586 12776737 17157259 17143292 12660246 15576399 21151179 15522869 17306568 19407812 17666529 21285352 19619488
EP300 YY1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 11486036 7758944 18542060 9199306 17510411
EP300 MYB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 19608861 29954426 18585056 15691758 10656693 25740244
EP300 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 137.0 1.0 Omnipath 11907332 25545885 21187340 10706102 16438982 10490106 19339993 15542844 23010591 11433299 19608861 17438265 17906639 16024799 9194564 20234175 23402884 12162806 26229107 16959611 15186775 9744860 11070080 17977830 17189186 22266186 20228809 15664194 19805293 25753752 11804596 26625199 27818144 10648616 16928824 9288740 10942770 12724314 23148227 23728348 15965232 19218448 16678111 16782091 20094059 14612423 24821727 10518217 16713569 9891054 25288747 17452980 14759370 19788416 25156994 18931695 22074660 23880760 15337767 15509808 26302407 22731250 18391200 16543236 19234109 21471221 23307557 25867071 12690203 15558054 18612383 23870121 18243116 19217391 22013068 16537920 16611888 18485870 9194565 12660246 9809062 23796514 11359905 12501250 15295102 19407812 25651062 23329847 16135789
TP53 GHRHR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10529175 24297337 11852084 24737129
TP53 HNF4A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 11818510 16895524
HNF4A MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12591729 23714368 19966299 15024077
KMT2A HOXA7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18082152 15941828
TP53 HSP90AA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15358769 15284248 24451373 18996350
HSP90AA1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 12427754 10557093 21460846 16713569 11507088
TP53 HSP90AB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 15052775 15284248 21478269
TP53 HSP90AB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 23443559 18431400 11707401 22939624
TP53 IGFBP3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 10101800 23810988 15661074 7566179 15713654 18084616 9525742 20003326
TP53 IGFBP3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 7566179 17409411 18431400
MEN1 KMT2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 17145710 15199122 19075677 16618927 17671196 22936661 22327296 15640349 16997566 20818375 20961854
KMT2A MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20677832 16510874
TP53 MKI67 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 21611785 11713584 10365096 15217513 16258956 14675138
MYB MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 18408764 19609274 8382794 1679531 1588953 1594249 9596659 11259163 8474446 2233716 16088151
YY1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 9797456 16314465 10528225 8266081 19279113 17287852 10713181 18490439 17434929 16878156 18542060
TBP MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 20886042 7880838 9797456 15876353 14506152
MYC PTEN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23135913 19578399 12695333
MYC TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 10962037 10656696 8494784 10348347 19882681 16557594 19086036 15780936 14519204 16112647 11781835 7969121 11789587 9839551
YY1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8266081 15805285 18490439 19219071 2191300
MYC NFYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 11282029 10446203
TP53 NOS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 11131279 11092782 9194524 8637893
YY1 OPRM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17990281 19164126 19765550
POMC OPRM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15464143
PAK1 VIM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 14722118 11895474 17081983 16565220 26369929 28390425 27457922 11420699 15713670 15766329 7983050 12458200 12761892 26956613 16964243 28096473 15345747
TP53 POMC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17350573 18510673 19098008 19449448 17630965 24917821
PPP1CA RB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 12202491 8380224 17274640 10773440 9315635 17008050 20694007 8384581 16189514 8380637 10889204 12434308
PPP1CA TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 16501611 16713569 15231748 15178317
PPP1CC TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 17145710 17274640 15178317 16501611
TP53 PTEN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 22957312 15843377 12917634 21637289 17344317 12839924 11545734 18172008 19173293 20554748 19079342 14984207
TP53 PTEN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 21336307 18431400 18339852 12620407 17409411 18172008 17823410 16713569 21518799 21483453
TP53 RB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 23.0 1.0 Omnipath 11850820 10029406 16931621 9774636 8845569 8270002 11244564 15618023 12444079 12749855 21496227 11818069 15827088 8720930 1608930 8119988 23474762 11121443 22729911 22894933 8355507
RB1 YY1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 12588874 11118439
WDR5 RBBP5 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
WDR5 RBBP5 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
YY1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10787423 10634504 8816507 10505791 18391986