Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list

Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins

Filter Graph:

0.5
Layout:
  🔂

Click a node or edge for more data...

Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
E2F4 H3C2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11799066
PHC2 BYSL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
XPO1 CTNNB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 19940019 18573912
DDB1 CTNNB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19651607 0902132106
E2F1 CTNNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 14706452 18794899
CTNNB1 SOX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 24291232 24482235
DNMT1 PHC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
PRKAA1 DNMT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 28143904
E2F1 DNMT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18319725 15867357
L3MBTL3 E2F1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0610279104 17517653
E2F2 E2F1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7958836
E2F1 E2F6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16107498
E2F1 TOP2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11313881
E2F1 E2F2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15014447 18319725
E2F2 L3MBTL3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0610279104 17517653
E2F4 L3MBTL3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0610279104 17517653
E2F6 L3MBTL3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0610279104 17517653
FXR2 PHC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
FXR2 L3MBTL3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
KDM1A PHC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
KDM1A L3MBTL3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
PHC2 L3MBTL3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
LHX2 PAX6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19146846 24262147
XPO1 TOP2A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19955415 0912384106
ASB6 E2F6 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SOX2 KDM1A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30442713 28794006
SOX2 TEAD1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 35140242 21532573
HIST1H3A SP100 â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
DDB1 HIST1H3A â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
MORF4L1 MORF4L2 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
BYSL FXR2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
DDB1 DCAF5 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 19966799 16949367 16964240
PLEKHF2 YY1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
HIST1H3A KDM1A â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
CTNNB1 HNF4A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12944908 25241761
E2F1 DNMT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24502362 17575144 15867357
E2F4 E2F1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 14576826 10208422
E2F4 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14576826 10766737 18319725
DCAF5 DDB1 â—¼   PHYSICAL_INTERACTION 963.0 0.96 STRING 36370105
DNMT1 H3C2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16357870 24074865 23326524 12435631 22466170
KDM1A H3C2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17277772 24371278 19098913 18187655
KDM1A H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 16223729 20210320 18343668 20228790 15620353
MAPK9 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 19623618 18423204 25639486 22074626 19667122 18604449
E2F6 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 18562691 18319725 9689056 12004135 12909625
E2F4 E2F2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17531812 21247883 9149906 15718499
PRKAA2 HNF4A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 12740371
PRKAA1 HNF4A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 12740371
PAX6 SOX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19666824 17825048 11358870