Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list
Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins
Filter Graph:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
ACSS2 SIRT3 â—¼   DEACETYLATION ✅ 3.0 0.9 Reactome
AKT1 SIRT1 â—¼   DEACETYLATION ✅ + 0.57 0.57 Signor
ANKLE2 SIRT2 â—¼   DEACETYLATION ✅ 2.0 0.8 Reactome
CIITA HDAC2 â—¼   DEACETYLATION ✅ - 0.41 0.41 Signor
CRTC1 SIRT1 â—¼   DEACETYLATION ✅ + 0.26 0.26 Signor
CSAG3 SIRT1 â—¼   DEACETYLATION ✅ 0.64 0.64 mint
CSAG3 TP53 â—¼   DEACETYLATION ✅ 0.44 0.44 mint
CTNNB1 SIRT1 â—¼   DEACETYLATION ✅ + 0.49 0.49 Signor
CYCS SIRT5 â—¼   DEACETYLATION ✅ 1.0 0.7 Reactome
CYP11A1 SIRT3 â—¼   DEACETYLATION ✅ + 0.2 0.2 Signor
DLAT SIRT3 â—¼   DEACETYLATION ✅ 1.0 0.7 intact
EP300 SIRT1 â—¼   DEACETYLATION ✅ - 0.83 0.83 Signor
FASN HDAC3 â—¼   DEACETYLATION ✅ + 0.2 0.2 Signor
FLI1 HDAC1 â—¼   DEACETYLATION ✅ + 0.2 0.2 Signor
FOXL2 SIRT1 â—¼   DEACETYLATION ✅ - 0.5 0.5 Signor
FOXO1 SIRT1 â—¼   DEACETYLATION ✅ 1.0 0.7 Reactome
FOXO1 SIRT1 â—¼   DEACETYLATION ✅ - 0.78 0.78 Signor
FOXO3 HDAC1 â—¼   DEACETYLATION ✅ + 0.34 0.34 Signor
FOXO3 SIRT1 â—¼   DEACETYLATION ✅ 2.0 0.8 Reactome
FOXO3 SIRT1 â—¼   DEACETYLATION ✅ - 0.9 0.9 Signor
FOXO3 SIRT3 â—¼   DEACETYLATION ✅ 2.0 0.8 Reactome
FOXO4 SIRT1 â—¼   DEACETYLATION ✅ 1.0 0.7 intact
FOXO4 SIRT1 â—¼   DEACETYLATION ✅ + 0.72 0.72 Signor
GAP43 LYPLA2 â—¼   DEACETYLATION ✅ - 0.45 0.45 Signor
GLI1 HDAC1 â—¼   DEACETYLATION ✅ + 0.59 0.59 Signor
GLUD1 SIRT3 â—¼   DEACETYLATION ✅ 3.0 0.9 Reactome
H4C6 HDAC1 â—¼   DEACETYLATION ✅ 1.0 0.7 intact
H4C6 HDAC4 â—¼   DEACETYLATION ✅ 1.0 0.7 intact
H4C6 HDAC5 â—¼   DEACETYLATION ✅ 1.0 0.7 intact
H4C6 HDAC6 â—¼   DEACETYLATION ✅ 1.0 0.7 intact
HDAC1 FLI1 â—¼   DEACETYLATION ✅ + 0.2 0.2 Signor
HDAC1 FOXO3 â—¼   DEACETYLATION ✅ + 0.34 0.34 Signor
HDAC1 GLI1 â—¼   DEACETYLATION ✅ + 0.59 0.59 Signor
HDAC1 H4C6 â—¼   DEACETYLATION ✅ 1.0 0.7 intact
HDAC1 SNAI1 â—¼   DEACETYLATION ✅ 1.0 0.7 intact
HDAC1 STAT3 â—¼   DEACETYLATION ✅ 1.0 0.7 Reactome
HDAC1 YY1 â—¼   DEACETYLATION ✅ - 0.79 0.79 Signor
HDAC2 CIITA â—¼   DEACETYLATION ✅ - 0.41 0.41 Signor
HDAC2 SNAI1 â—¼   DEACETYLATION ✅ 1.0 0.7 intact
HDAC2 STAT3 â—¼   DEACETYLATION ✅ 1.0 0.7 Reactome
HDAC2 YY1 â—¼   DEACETYLATION ✅ - 0.77 0.77 Signor
HDAC3 FASN â—¼   DEACETYLATION ✅ + 0.2 0.2 Signor
HDAC3 SNAI1 â—¼   DEACETYLATION ✅ 1.0 0.7 intact
HDAC3 STAT3 â—¼   DEACETYLATION ✅ 1.0 0.7 Reactome
HDAC3 YY1 â—¼   DEACETYLATION ✅ - 0.6 0.6 Signor
HDAC4 H4C6 â—¼   DEACETYLATION ✅ 1.0 0.7 intact
HDAC4 RUNX2 â—¼   DEACETYLATION ✅ - 0.52 0.52 Signor
HDAC5 H4C6 â—¼   DEACETYLATION ✅ 1.0 0.7 intact
HDAC5 RUNX2 â—¼   DEACETYLATION ✅ - 0.45 0.45 Signor
HDAC6 H4C6 â—¼   DEACETYLATION ✅ 1.0 0.7 intact
HDAC6 SRSF2 â—¼   DEACETYLATION ✅ + 0.36 0.36 Signor
HDAC6 TUBA1A â—¼   DEACETYLATION ✅ 0.53 0.53 mint
HDAC6 TUBA1A â—¼   DEACETYLATION ✅ 2.0 0.8 intact
HDAC7 PLAG1 â—¼   DEACETYLATION ✅ - 0.26 0.26 Signor
HDAC7 PLAGL2 â—¼   DEACETYLATION ✅ - 0.26 0.26 Signor
HDAC8 TP53 â—¼   DEACETYLATION ✅ - 0.45 0.45 Signor
IDH2 SIRT3 â—¼   DEACETYLATION ✅ 3.0 0.9 Reactome
IDH2 SIRT3 â—¼   DEACETYLATION ✅ + 0.61 0.61 Signor
KAT2B SIRT1 â—¼   DEACETYLATION ✅ 1.0 0.7 intact
LDHB SIRT5 â—¼   DEACETYLATION ✅ + 0.2 0.2 Signor
LYPLA2 GAP43 â—¼   DEACETYLATION ✅ - 0.45 0.45 Signor
MYOD1 SIRT2 â—¼   DEACETYLATION ✅ - 0.37 0.37 Signor
NHLH2 SIRT1 â—¼   DEACETYLATION ✅ + 0.4 0.4 Signor
NOTCH1 SIRT1 â—¼   DEACETYLATION ✅ - 0.38 0.38 Signor
NOTUM WNT3A â—¼   DEACETYLATION ✅ 1.0 0.7 intact
PCK1 SIRT2 â—¼   DEACETYLATION ✅ + 0.39 0.39 Signor
PDHA1 SIRT3 â—¼   DEACETYLATION ✅ - 0.46 0.46 Signor
PGAM1 SIRT2 â—¼   DEACETYLATION ✅ + 0.26 0.26 Signor
PGAM2 SIRT2 â—¼   DEACETYLATION ✅ + 0.2 0.2 Signor
PLAG1 HDAC7 â—¼   DEACETYLATION ✅ - 0.26 0.26 Signor
PLAGL2 HDAC7 â—¼   DEACETYLATION ✅ - 0.26 0.26 Signor
PPARGC1A SIRT1 â—¼   DEACETYLATION ✅ + 0.77 0.77 Signor
RB1 SIRT1 â—¼   DEACETYLATION ✅ 1.0 0.7 intact
RBBP8 SIRT6 â—¼   DEACETYLATION ✅ 1.0 0.7 Reactome
RELA SIRT1 â—¼   DEACETYLATION ✅ 1.0 0.7 intact
RELA SIRT2 â—¼   DEACETYLATION ✅ 1.0 0.7 intact
RUNX2 HDAC4 â—¼   DEACETYLATION ✅ - 0.52 0.52 Signor
RUNX2 HDAC5 â—¼   DEACETYLATION ✅ - 0.45 0.45 Signor
SAR1A SIRT7 â—¼   DEACETYLATION ✅ + 0.2 0.2 Signor
SIRT1 AKT1 â—¼   DEACETYLATION ✅ + 0.57 0.57 Signor
SIRT1 CRTC1 â—¼   DEACETYLATION ✅ + 0.26 0.26 Signor
SIRT1 CSAG3 â—¼   DEACETYLATION ✅ 0.64 0.64 mint
SIRT1 CTNNB1 â—¼   DEACETYLATION ✅ + 0.49 0.49 Signor
SIRT1 EP300 â—¼   DEACETYLATION ✅ - 0.83 0.83 Signor
SIRT1 FOXL2 â—¼   DEACETYLATION ✅ - 0.5 0.5 Signor
SIRT1 FOXO1 â—¼   DEACETYLATION ✅ 1.0 0.7 Reactome
SIRT1 FOXO1 â—¼   DEACETYLATION ✅ - 0.78 0.78 Signor
SIRT1 FOXO3 â—¼   DEACETYLATION ✅ 2.0 0.8 Reactome
SIRT1 FOXO3 â—¼   DEACETYLATION ✅ - 0.9 0.9 Signor
SIRT1 FOXO4 â—¼   DEACETYLATION ✅ 1.0 0.7 intact
SIRT1 FOXO4 â—¼   DEACETYLATION ✅ + 0.72 0.72 Signor
SIRT1 KAT2B â—¼   DEACETYLATION ✅ 1.0 0.7 intact
SIRT1 NHLH2 â—¼   DEACETYLATION ✅ + 0.4 0.4 Signor
SIRT1 NOTCH1 â—¼   DEACETYLATION ✅ - 0.38 0.38 Signor
SIRT1 PPARGC1A â—¼   DEACETYLATION ✅ + 0.77 0.77 Signor
SIRT1 RB1 â—¼   DEACETYLATION ✅ 1.0 0.7 intact
SIRT1 RELA â—¼   DEACETYLATION ✅ 1.0 0.7 intact
SIRT1 SMAD7 â—¼   DEACETYLATION ✅ - 0.45 0.45 Signor
SIRT1 SUV39H1 â—¼   DEACETYLATION ✅ 1.0 0.7 intact
SIRT1 TP53 â—¼   DEACETYLATION ✅ 1.0 0.7 intact
SIRT1 XBP1 â—¼   DEACETYLATION ✅ - 0.34 0.34 Signor
SIRT1 XPA â—¼   DEACETYLATION ✅ 1.0 0.7 intact
SIRT1 XPA â—¼   DEACETYLATION ✅ + 0.49 0.49 Signor
SIRT1 XRCC6 â—¼   DEACETYLATION ✅ 1.0 0.7 intact
SIRT1 XRCC6 â—¼   DEACETYLATION ✅ 1.0 0.7 intact
SIRT2 ANKLE2 â—¼   DEACETYLATION ✅ 2.0 0.8 Reactome
SIRT2 MYOD1 â—¼   DEACETYLATION ✅ - 0.37 0.37 Signor
SIRT2 PCK1 â—¼   DEACETYLATION ✅ + 0.39 0.39 Signor
SIRT2 PGAM1 â—¼   DEACETYLATION ✅ + 0.26 0.26 Signor
SIRT2 PGAM2 â—¼   DEACETYLATION ✅ + 0.2 0.2 Signor
SIRT2 RELA â—¼   DEACETYLATION ✅ 1.0 0.7 intact
SIRT3 ACSS2 â—¼   DEACETYLATION ✅ 3.0 0.9 Reactome
SIRT3 CYP11A1 â—¼   DEACETYLATION ✅ + 0.2 0.2 Signor
SIRT3 DLAT â—¼   DEACETYLATION ✅ 1.0 0.7 intact
SIRT3 FOXO3 â—¼   DEACETYLATION ✅ 2.0 0.8 Reactome
SIRT3 GLUD1 â—¼   DEACETYLATION ✅ 3.0 0.9 Reactome
SIRT3 IDH2 â—¼   DEACETYLATION ✅ 3.0 0.9 Reactome
SIRT3 IDH2 â—¼   DEACETYLATION ✅ + 0.61 0.61 Signor
SIRT3 PDHA1 â—¼   DEACETYLATION ✅ - 0.46 0.46 Signor
SIRT3 SOD2 â—¼   DEACETYLATION ✅ 3.0 0.9 Reactome
SIRT3 SOD2 â—¼   DEACETYLATION ✅ + 0.6 0.6 Signor
SIRT5 CYCS â—¼   DEACETYLATION ✅ 1.0 0.7 Reactome
SIRT5 LDHB â—¼   DEACETYLATION ✅ + 0.2 0.2 Signor
SIRT6 RBBP8 â—¼   DEACETYLATION ✅ 1.0 0.7 Reactome
SIRT6 TNF â—¼   DEACETYLATION ✅ + 0.29 0.29 Signor
SIRT7 SAR1A â—¼   DEACETYLATION ✅ + 0.2 0.2 Signor
SIRT7 TP53 â—¼   DEACETYLATION ✅ - 0.46 0.46 Signor
SMAD7 SIRT1 â—¼   DEACETYLATION ✅ - 0.45 0.45 Signor
SNAI1 HDAC1 â—¼   DEACETYLATION ✅ 1.0 0.7 intact
SNAI1 HDAC2 â—¼   DEACETYLATION ✅ 1.0 0.7 intact
SNAI1 HDAC3 â—¼   DEACETYLATION ✅ 1.0 0.7 intact
SOD2 SIRT3 â—¼   DEACETYLATION ✅ 3.0 0.9 Reactome
SOD2 SIRT3 â—¼   DEACETYLATION ✅ + 0.6 0.6 Signor
SRSF2 HDAC6 â—¼   DEACETYLATION ✅ + 0.36 0.36 Signor
STAT3 HDAC1 â—¼   DEACETYLATION ✅ 1.0 0.7 Reactome
STAT3 HDAC2 â—¼   DEACETYLATION ✅ 1.0 0.7 Reactome
STAT3 HDAC3 â—¼   DEACETYLATION ✅ 1.0 0.7 Reactome
SUV39H1 SIRT1 â—¼   DEACETYLATION ✅ 1.0 0.7 intact
TNF SIRT6 â—¼   DEACETYLATION ✅ + 0.29 0.29 Signor
TP53 CSAG3 â—¼   DEACETYLATION ✅ 0.44 0.44 mint
TP53 HDAC8 â—¼   DEACETYLATION ✅ - 0.45 0.45 Signor
TP53 SIRT1 â—¼   DEACETYLATION ✅ 1.0 0.7 intact
TP53 SIRT7 â—¼   DEACETYLATION ✅ - 0.46 0.46 Signor
TUBA1A HDAC6 â—¼   DEACETYLATION ✅ 0.53 0.53 mint
TUBA1A HDAC6 â—¼   DEACETYLATION ✅ 2.0 0.8 intact
WNT3A NOTUM â—¼   DEACETYLATION ✅ 1.0 0.7 intact
XBP1 SIRT1 â—¼   DEACETYLATION ✅ - 0.34 0.34 Signor
XPA SIRT1 â—¼   DEACETYLATION ✅ 1.0 0.7 intact
XPA SIRT1 â—¼   DEACETYLATION ✅ + 0.49 0.49 Signor
XRCC6 SIRT1 â—¼   DEACETYLATION ✅ 1.0 0.7 intact
XRCC6 SIRT1 â—¼   DEACETYLATION ✅ 1.0 0.7 intact
YY1 HDAC1 â—¼   DEACETYLATION ✅ - 0.79 0.79 Signor
YY1 HDAC2 â—¼   DEACETYLATION ✅ - 0.77 0.77 Signor
YY1 HDAC3 â—¼   DEACETYLATION ✅ - 0.6 0.6 Signor