ATM
|
H2AX
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
1106300109
22451927
|
MDM2
|
ATM
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
19816404
21986495
|
FOXO3
|
ATM
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18344987
18424439
|
ATM
|
H2AX
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
16858402
5218840
|
BAX
|
SNCA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
SMAD3
|
BAX
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
11906909
16603637
|
AHR
|
BAX
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11455387
11479581
|
FASLG
|
BID
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15659383
25241761
|
BID
|
CYCS
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9873064
9727491
|
FOXO3
|
CDKN2D
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17873901
|
CEBPG
|
APOA1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
8175747
15109267
|
CEBPG
|
PPARG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10862621
12524424
|
CEBPG
|
PRKACA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9774647
8626491
|
FOXO3
|
HIF1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
18268343
0706790105
|
FOXO3
|
CCND2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
12391153
15509806
|
FOXO3
|
AKT1
|
â—¼ PHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
10102273
5211323
|
FOXO3
|
SIRT1
|
â—¼ DEACETYLATION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
14976264
23665396
|
FOXO3
|
SIRT3
|
â—¼ DEACETYLATION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
14976264
23665396
|
AR
|
FOXO3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
18391971
|
FOXO4
|
SOD2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
21536589
|
FOXO4
|
PPARGC1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17390079
|
STK4
|
FOXO4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
21106439
18394876
|
PAK2
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5218167
16374509
|
NKX2-1
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
SPRYD4
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
6169676
16893902
|
APP
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
12485888
5215996
|
PIK3CA
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
GRB2
|
HSPA5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5216105
12577067
|
GRB2
|
RPL21
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5216105
12577067
|
GRB2
|
SLC25A4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5216105
12577067
|
GRB2
|
PLD2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
6731738
16407827
|
GRB2
|
HSPA1L
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5216105
12577067
|
GRB2
|
AP2A1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5216105
12577067
|
GRB2
|
SMAD3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
GRB2
|
ATP5F1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5216105
12577067
|
GRB2
|
SMARCA5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5216105
12577067
|
TFAP2B
|
KAT5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
BAAT
|
KAT5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
KAT5
|
NDUFA5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
KAT5
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
KAT5
|
GADD45G
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15383276
5217202
|
KAT5
|
NDUFV2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
KAT5
|
AR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
10364196
5211544
|
SIRT1
|
KAT5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
20100829
|
HIF1A
|
MDM2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12606552
15385570
|
ELF4
|
MDM2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19380490
23393136
|
MDM2
|
RELA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
21988832
23839035
|
PSMD4
|
PSMA3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16990800
5219132
|
PRKACA
|
PSMD2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
PSMD2
|
PSMD4
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
16990800
5219132
|
SIRT1
|
ATG5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
18296641
0712145105
|
FOXL2
|
SIRT1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19010791
|
SMAD3
|
SIRT1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
22610349
23161884
|
SIRT1
|
AKT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
21775285
|
SMARCA2
|
HSPA5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
SMARCA5
|
H2AFX
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
ACSN
|
19092802
19234442
|
SIRT3
|
SOD2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
ACSN
|
21109197
22850421
|
AR
|
SOD2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20610535
18829485
|
AR
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
19481544
7103716
|
TP53
|
PSMD11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
TP53
|
HSPA5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17184779
5219502
|
TP53
|
HSPA1L
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17184779
5219502
|
TP53
|
GSTM4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
AURKA
|
TP53
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
14702041
19121998
|
TP53
|
SMAD3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
21900401
|
TP53
|
IFNA13
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19416861
22509910
|
TP53
|
CCNG2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
8806701
19427386
|
TP53
|
PRDM2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
20594067
20557878
|
TP53
|
GPX1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16980608
|
TP53
|
FASLG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10969818
|
TP53
|
MET
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18431400
|
TP53
|
GPX1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18431400
|
TP53
|
HRAS
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18431400
|
RELA
|
GADD45G
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23681230
|
NFKB1
|
GADD45G
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23681230
|
COX5B
|
COX4I2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
ACSN
|
17418790
8194600
|
COX5B
|
COX4I2
|
â—¼ SHARES_COMPLEX
|
|
|
2.0
|
0.8
|
ACSN
|
17418790
8194600
|
CALM1
|
AKT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12799359
11988487
|
AR
|
CALM1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16619263
20610535
|
CALM1
|
ADCY8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16258073
10075700
|
ATP5PO
|
ATP5F1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
CYCS
|
SNCA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
CYCS
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
PPARGC1A
|
CYCS
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12533512
18046414
|
RELA
|
BECN1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19289499
19458474
|
HSPA1L
|
RIPK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
HSPA1L
|
RELB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
DCTN1
|
CRYAB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
26465331
0133994
|
AHR
|
CRYAB
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
21494593
18805402
|
COX7C
|
COX4I2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
ACSN
|
17418790
8194600
|
COX7C
|
COX4I2
|
â—¼ SHARES_COMPLEX
|
|
|
2.0
|
0.8
|
ACSN
|
17418790
8194600
|
AHR
|
VEGFA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
17413038
19182260
|
TNIK
|
MAP3K7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
1001376
22904686
|
MAP2K7
|
MAP3K7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5219344
17110930
|
PRKACA
|
SMAD3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
SMAD3
|
CHUK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
0712044105
18268325
|
SMAD3
|
PSMD11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15231748
5217094
|
SMAD3
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
AR
|
SMAD3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
20739403
20610535
|
SMAD3
|
MET
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15339794
|
SMAD3
|
AHR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11259615
|
EIF4E
|
SMAD3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12150994
23331499
|
RELB
|
IL6
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
19687301
23874122
|
HRAS
|
KLC3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
HRAS
|
ERBB2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
23220880
22908275
|
ERBB2
|
HRAS
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17496910
17673906
|
HRAS
|
PIK3CB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9069260
21779497
|
NDUFA1
|
GOLGB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
NDUFA9
|
SIRT3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
18794531
0803790105
|
HAP1
|
NDUFB9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
NDUFS3
|
NDUFS2
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.8
|
0.8
|
mint
|
24344204
|
NDUFV2
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
FOXL2
|
PPARGC1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17360647
|
RHEB
|
HIP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
BAAT
|
HIP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
COX5A
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
COX5A
|
COX4I2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
ACSN
|
17418790
8194600
|
COX5A
|
COX4I2
|
â—¼ SHARES_COMPLEX
|
|
|
2.0
|
0.8
|
ACSN
|
17418790
8194600
|
COX6C
|
COX4I2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
ACSN
|
17418790
8194600
|
COX6C
|
COX4I2
|
â—¼ SHARES_COMPLEX
|
|
|
2.0
|
0.8
|
ACSN
|
17418790
8194600
|
CHUK
|
RELB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
CHUK
|
AURKA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17939994
0706493104
|
RELA
|
RIPK2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19693652
|
RELA
|
PPARD
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
14708613
|
RELA
|
EPAS1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20495570
|
PPARG
|
APOB
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
16542871
|
PPARG
|
NFATC1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
19953004
14573767
|
PPARG
|
GSTA2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15150131
|
AP2A2
|
AP2A1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
ACSN
|
15749704
15911768
|
AP2A2
|
AP2A1
|
â—¼ SHARES_COMPLEX
|
|
|
2.0
|
0.8
|
ACSN
|
15749704
15911768
|
HSPA5
|
RELB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
VHL
|
HIF1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5218395
16511565
|
SIRT3
|
HIF1A
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
ACSN
|
21109197
22850421
|
PRKACA
|
AKT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
NFKB1
|
AKT1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
18031796
|
NFKB1
|
RIPK2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19693652
|
NFKB1
|
SELP
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
7559449
9488441
|
NFKB1
|
CCND2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
21790895
|
SNCA
|
PRKCA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
PRKCA
|
PRKD3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16198087
|
APP
|
NLRP3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
17349957
17703304
|
PIK3CD
|
IRS2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
11598010
12506011
|
AR
|
IRS2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19318566
20610535
|
PSMD4
|
PSMD12
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16990800
5219132
|
HAP1
|
PSMD11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
HSP90B1
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
PIK3CB
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
PPP3CC
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
HSPA5
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
PRKACA
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
GSTM4
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
DCTN2
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
MAP2K2
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
PRKACG
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
SNCA
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
APP
|
PLD2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
AR
|
APP
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20610535
16987234
|
PRKACA
|
PLCB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
8657310
9660757
|
DCTN2
|
SOD1
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
8141566
21252941
|
MET
|
PIK3CA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
10871282
10648629
|
PIK3CD
|
PIK3CA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
9885561
10455108
|
PIK3CA
|
PIK3CB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
9885561
10455108
|
PIK3CA
|
KL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
15863030
11353842
|
ERBB2
|
PIK3CA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17496910
8026468
|
PIK3CD
|
PIK3CB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
9885561
10455108
|
ATF1
|
ERBB2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10698518
|
AR
|
PRKD3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20610535
20813663
|
AR
|
HSPA5
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20610535
21125667
|
AR
|
MMP1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
17636177
8798622
|
AR
|
AHR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20610535
23689136
|
AR
|
PIK3CB
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23365759
20610535
|
AHR
|
AR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19815066
17392787
|
PPP3CC
|
NFATC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11062529
18676376
|
AHR
|
MMP1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19755661
15075337
|
GOLGB1
|
COX4I2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
ERO1A
|
TNIK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
GRM5
|
HOMER3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
9808458
9069287
|
GRM5
|
HOMER2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
9808458
9069287
|
ERO1A
|
P4HB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5212958
10970843
|
GRM1
|
HOMER2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
9808458
9069287
|
GRM1
|
HOMER3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
9808458
9069287
|
FOXO3
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
808.0
|
0.8
|
STRING
|
36370105
|
GRB2
|
MET
|
â—¼ PHYSICAL_INTERACTION
|
|
|
808.0
|
0.8
|
STRING
|
36370105
|
MCC
|
CSNK1E
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.81
|
0.81
|
mint
|
21900206
2001699
8089645
|
MDM2
|
PSMD4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.81
|
0.81
|
HIPPIE
|
19240029
22350919
20479273
24583282
24121268
22659184
|
AKT1
|
MDM2
|
â—¼ PHOSPHORYLATION
|
✅
|
|
0.81
|
0.81
|
mint
|
5217292
15527798
|
MDM2
|
AKT1
|
â—¼ PHOSPHORYLATION
|
✅
|
|
0.81
|
0.81
|
mint
|
5217292
15527798
|
APP
|
SNCA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
811.0
|
0.81
|
STRING
|
36370105
|
CRYAB
|
SNCA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
817.0
|
0.81
|
STRING
|
36370105
|
NDUFA5
|
NDUFV3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
817.0
|
0.81
|
STRING
|
36370105
|
VHL
|
ATM
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
17353931
16678111
|
PSMD2
|
MDM2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
20479273
18086887
|
PSMD9
|
PSMD2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
26344197
|
PSMD3
|
PSMD9
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
26344197
|
H2AX
|
HDAC2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
31504778
28242625
|
COX6C
|
COX7C
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
31536960
33961781
|
COX6C
|
COX5A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
31536960
23260140
|
SKP2
|
AKT1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
19270695
21358672
23911321
19270694
|
PSMD9
|
PSMD4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
26344197
|
PSMD9
|
PSMD6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
26344197
|
COX5B
|
COX6C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
821.0
|
0.82
|
STRING
|
36370105
|
COX5A
|
NDUFA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
823.0
|
0.82
|
STRING
|
36370105
|
COX5A
|
NDUFA5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
823.0
|
0.82
|
STRING
|
36370105
|
COX5A
|
NDUFC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
823.0
|
0.82
|
STRING
|
36370105
|
AKT1
|
FOXO4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
10217147
16272144
15688030
11313479
11689711
|
PPARD
|
MDM2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
GSTM2
|
GSTM4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
COX6B1
|
NDUFB9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
832.0
|
0.83
|
STRING
|
36370105
|
COX6B1
|
NDUFA9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
833.0
|
0.83
|
STRING
|
36370105
|
KAT5
|
MDM2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
835.0
|
0.83
|
STRING
|
36370105
|
MAP3K7
|
RIPK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
835.0
|
0.83
|
STRING
|
36370105
|
GRB2
|
IRS2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
7559579
22974441
9852124
21706016
|
BECN1
|
ERBB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
28205554
23703612
28628118
28351972
|
HDAC2
|
PPARD
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
11867749
25241761
|
AKT1
|
SKP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
839.0
|
0.84
|
STRING
|
36370105
|
AKT1
|
AURKA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
28628118
24412244
28205554
|
KIF5C
|
KLC3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
33961781
11319135
|
APOA1
|
APOB
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
28183703
7592581
19164805
|
FOXO3
|
MDM2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
840.0
|
0.84
|
STRING
|
36370105
|
NDUFA9
|
NDUFC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
845.0
|
0.84
|
STRING
|
36370105
|
HDAC2
|
HIF1A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
25241761
11641274
|
ERBB2
|
GRB2
|
â—¼ RELOCALIZATION
|
✅
|
+
|
0.85
|
0.85
|
Signor
|
14967450
|
COX6C
|
COX7C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
856.0
|
0.85
|
STRING
|
36370105
|
CHUK
|
RELA
|
â—¼ PHOSPHORYLATION
|
✅
|
+
|
0.85
|
0.85
|
Signor
|
10521409
|
COX5A
|
NDUFS3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
861.0
|
0.86
|
STRING
|
36370105
|
COX5A
|
NDUFA9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
866.0
|
0.86
|
STRING
|
36370105
|
NDUFA1
|
NDUFB9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
868.0
|
0.86
|
STRING
|
36370105
|
NDUFA5
|
NDUFC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
868.0
|
0.86
|
STRING
|
36370105
|
NDUFC1
|
NDUFS2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
868.0
|
0.86
|
STRING
|
36370105
|
NDUFC1
|
NDUFV2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
868.0
|
0.86
|
STRING
|
36370105
|
ATM
|
H2AX
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
16858402
27918549
22184063
9488723
32518374
20081839
18344987
21676867
22451927
21704408
11571274
11893489
26095369
|
HDAC2
|
VHL
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
22286234
11641274
|
AURKA
|
NFKB1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
27609421
33961781
25609649
26186194
|
GSTA2
|
GSTA5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
32296183
33961781
26186194
|
PEX3
|
PEX16
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
16280322
32296183
34079125
|
HIF1A
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
AKT1
|
AR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
KAT5
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
871.0
|
0.87
|
STRING
|
36370105
|
HRAS
|
PIK3CA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
871.0
|
0.87
|
STRING
|
36370105
|
NDUFB9
|
SDHB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
871.0
|
0.87
|
STRING
|
36370105
|
RELA
|
RELB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
871.0
|
0.87
|
STRING
|
36370105
|
AKT1
|
CHUK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
872.0
|
0.87
|
STRING
|
36370105
|
GSTM2
|
GSTM4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
872.0
|
0.87
|
STRING
|
36370105
|
AKR1C1
|
AKR1C3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
872.0
|
0.87
|
STRING
|
36370105
|
HDAC2
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
873.0
|
0.87
|
STRING
|
36370105
|
APP
|
CRYAB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
873.0
|
0.87
|
STRING
|
36370105
|
CHUK
|
MAP3K7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
873.0
|
0.87
|
STRING
|
36370105
|
HIF1A
|
MDM2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
874.0
|
0.87
|
STRING
|
36370105
|
HIF1A
|
VEGFA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
874.0
|
0.87
|
STRING
|
36370105
|
AURKA
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
875.0
|
0.87
|
STRING
|
36370105
|
EIF2AK3
|
HSPA5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
877.0
|
0.87
|
STRING
|
36370105
|
CHUK
|
RELA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
878.0
|
0.87
|
STRING
|
36370105
|
AKT1
|
FOXO3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
21621563
10102273
25241761
21775285
|
MDM2
|
FOXO4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
20874444
18665269
21525355
|
DCTN1
|
GRB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
8955163
16189514
|
BECN1
|
AKT1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
29669822
23112296
28628118
28205554
|
AKT1
|
PIK3CA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
880.0
|
0.88
|
STRING
|
36370105
|
HDAC2
|
RELA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
883.0
|
0.88
|
STRING
|
36370105
|
ATM
|
H2AFX
|
â—¼ PHYSICAL_INTERACTION
|
|
|
885.0
|
0.88
|
STRING
|
36370105
|
SIRT1
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
885.0
|
0.88
|
STRING
|
36370105
|
COX4I2
|
CYCS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
885.0
|
0.88
|
STRING
|
36370105
|
SMAD3
|
FOXO3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
15084259
24920680
21532621
|
PSMD2
|
PSMD3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
25036637
33961781
28292943
22939629
26344197
|
HIF1A
|
SMAD3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
12228247
28471448
11486006
14741200
|
CALM1
|
SNCA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
894.0
|
0.89
|
STRING
|
36370105
|
TP53
|
ATM
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
9843217
9733515
9733514
|
FOXO3
|
ATM
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
18344987
|
KAT5
|
ATM
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16141325
|
ATM
|
AKT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
15546863
15899889
|
ATM
|
ATF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
20730097
|
BAX
|
BID
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
25241761
15574335
20956295
23374347
17289999
|
HIF1A
|
BID
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
15240700
12402042
15024076
|
PRKCA
|
CDKN2D
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
22558186
|
CEBPG
|
GSTA2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12509401
12601366
12663507
|
ARHGEF1
|
CSNK1E
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
FOXO3
|
PIK3CA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
19299143
18644865
|
FOXO4
|
AKT1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
11896584
11313479
11689711
|
PIK3CD
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
11002419
10995764
10448070
|
PIK3CB
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
11002419
10995764
10448070
|
RAP1A
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
12005431
9566877
7997267
|
MET
|
GRB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
11063574
15546961
9660480
19433454
21222362
7511210
8662889
11439336
|
IRS2
|
GRB2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
ACSN
|
19109239
7890616
9535722
|
KAT5
|
MDM2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
18499675
11927554
18264029
19150978
|
MDM2
|
KAT5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
11927554
16904321
|
AR
|
MDM2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
899.0
|
0.9
|
STRING
|
36370105
|
AKT1
|
MDM2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
899.0
|
0.9
|
STRING
|
36370105
|
HIF1A
|
MDM2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
12606552
10640274
25447306
15880652
19696166
25535359
17234751
15385570
|
SIRT1
|
PPARG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
15850715
21633182
|
FOXL2
|
SIRT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
19010791
|
SOD2
|
SIRT3
|
â—¼ DEACETYLATION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
18680753
17923681
16788062
|
PPARG
|
TP53
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16887883
14960510
|
TP53
|
HSPA5
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
15212714
20097177
18840615
|
CALM1
|
AKT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
9859994
2550447
19608982
|
TFAP2B
|
CRYAB
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
21556774
|
MAP3K7
|
NDUFS6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
MAP2K7
|
MAP3K7
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
15837794
8533096
16186825
|
MAP3K7
|
SMAD3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
9380693
|
AKT1
|
SMAD3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
16362038
25241761
|
SMAD3
|
CCND2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16055503
24416423
|
NFATC1
|
IL6
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
21515435
17079331
|
HRAS
|
PAK2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
15520807
17462920
20363321
|
MAP2K2
|
RAP1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
27503831
16939974
9560161
|
PPARD
|
PPARGC1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
17084713
17275789
18509063
|
AHR
|
FASLG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
15550680
15972635
16399633
|
RELA
|
MET
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
19530226
20186924
|
RELA
|
AR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
16713569
8798655
|
PPARD
|
PPARG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
20097210
10991946
20176998
|
HIF1A
|
PPARG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
18461556
19490906
11879638
|
PPARG
|
KL
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
18756295
16709611
18547997
|
NFKB1
|
HIF1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
18498249
17898080
|
HIF1A
|
MMP1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
17335808
18588890
20102637
|
IDH2
|
SIRT3
|
â—¼ DEACETYLATION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
18680753
17923681
16788062
|
AKT1
|
DCTN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
IRS2
|
PIK3CD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
9113989
|
DCTN4
|
DCTN1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
26638075
33961781
27173435
28718761
34079125
26344197
|
DCTN1
|
DCTN2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
26638075
33961781
22956769
26186194
27173435
34079125
22939629
26344197
|
DCTN4
|
DCTN2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
22863883
33961781
27173435
26186194
28718761
26344197
|
AR
|
MET
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
20610535
20946682
17283128
|
POLR2E
|
HSP90B1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
NFATC1
|
SNCA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
18802087
24590765
23070399
|
HDAC2
|
SMARCA5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
900.0
|
0.9
|
STRING
|
36370105
|
BAX
|
BID
|
â—¼ PHYSICAL_INTERACTION
|
|
|
901.0
|
0.9
|
STRING
|
36370105
|
NDUFS2
|
SDHB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
901.0
|
0.9
|
STRING
|
36370105
|
SIRT1
|
FOXO3
|
â—¼ DEACETYLATION
|
✅
|
-
|
0.9
|
0.9
|
Signor
|
24003218
|
ATM
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
915.0
|
0.91
|
STRING
|
36370105
|
PSMA8
|
PSMD14
|
â—¼ PHYSICAL_INTERACTION
|
|
|
916.0
|
0.91
|
STRING
|
36370105
|
PSMA8
|
PSMD13
|
â—¼ PHYSICAL_INTERACTION
|
|
|
916.0
|
0.91
|
STRING
|
36370105
|
PSMA8
|
PSMD3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
917.0
|
0.91
|
STRING
|
36370105
|
PSMA8
|
PSMD6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
917.0
|
0.91
|
STRING
|
36370105
|
GRB2
|
ERBB2
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.92
|
0.92
|
mint
|
16273093
5218056
|
H2AX
|
KAT5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.92
|
0.92
|
HIPPIE
|
23777805
20224553
18406329
|
PSMA8
|
PSMB5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
928.0
|
0.92
|
STRING
|
36370105
|
AKT1
|
FOXO3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
939.0
|
0.94
|
STRING
|
36370105
|
AKT1
|
STK4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.94
|
0.94
|
HIPPIE
|
19940129
17932490
|
SOD1
|
SOD2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
944.0
|
0.94
|
STRING
|
36370105
|
PSMA3
|
PSMA8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
945.0
|
0.94
|
STRING
|
36370105
|
PSMB5
|
PSMD13
|
â—¼ PHYSICAL_INTERACTION
|
|
|
945.0
|
0.94
|
STRING
|
36370105
|
PSMA8
|
PSMD2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
945.0
|
0.94
|
STRING
|
36370105
|
PSMA1
|
PSMA8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
945.0
|
0.94
|
STRING
|
36370105
|
FOXO3
|
SIRT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
946.0
|
0.94
|
STRING
|
36370105
|
COX5B
|
COX6B1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
946.0
|
0.94
|
STRING
|
36370105
|
COX6B1
|
COX7C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
946.0
|
0.94
|
STRING
|
36370105
|
DCTN1
|
HAP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.95
|
0.95
|
HIPPIE
|
9361024
9454836
|
COX5A
|
COX6A2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
952.0
|
0.95
|
STRING
|
36370105
|
COX6A2
|
COX6C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
952.0
|
0.95
|
STRING
|
36370105
|
COX5B
|
COX7C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
955.0
|
0.95
|
STRING
|
36370105
|
POLR2A
|
SMARCA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
956.0
|
0.95
|
STRING
|
36370105
|
COX5A
|
NDUFS6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
956.0
|
0.95
|
STRING
|
36370105
|
ERBB2
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
957.0
|
0.95
|
STRING
|
36370105
|
AKT1
|
MDM2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
32450252
25241761
18332867
12145204
19166854
15527798
20856200
11715018
23397142
11504915
11923280
21930127
|
PSMD6
|
PSMD2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
17353931
22863883
33961781
28292943
22939629
26344197
|
COX5A
|
NDUFB9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
959.0
|
0.96
|
STRING
|
36370105
|
EPAS1
|
VHL
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
17967880
26735578
10823831
30487161
26342197
11331613
12604794
15611064
10353251
21685897
28775317
17339318
25500545
23401859
17986458
33591636
10878807
11292862
24981860
|
COX5A
|
NDUFS2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
960.0
|
0.96
|
STRING
|
36370105
|
COX5A
|
NDUFV2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
960.0
|
0.96
|
STRING
|
36370105
|
DCTN1
|
DCTN4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
960.0
|
0.96
|
STRING
|
36370105
|
CHUK
|
NFKB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
965.0
|
0.96
|
STRING
|
36370105
|
COX6B1
|
COX6C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
966.0
|
0.96
|
STRING
|
36370105
|
ERBB2
|
GRB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
9710588
11173924
21278786
16713569
9756944
24189400
31980649
22973453
24658140
30898150
16273093
17875712
16729043
11606575
8665853
|
PSMD4
|
PSMD3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
16990800
22863883
33961781
30479383
22939629
26344197
|
NFKB1
|
RELB
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
28514442
14743216
27609421
21988832
17962807
35140242
33961781
25609649
22808155
|
HIF1A
|
VHL
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
15082527
11865071
11226425
10944113
14556007
11986208
15527772
17973296
12538644
26735336
24899725
12606543
21358672
24015760
16611863
23401859
18062927
21332579
15805242
19940151
12086861
27281823
23413029
33060856
11292862
24316222
16155211
24857547
22932900
29121446
11292861
12101228
15060148
18047470
16278378
21602890
27320910
12464182
26611735
32589900
18402654
25500545
12050673
18694926
26215701
10878807
25361009
11641274
22351759
34007068
18305400
21316481
11024059
34195792
26037477
34174286
33039559
10823831
26743088
31810986
10353251
15833858
17558023
11566883
23580587
27563096
18985005
19123984
25438054
12682018
18323857
23387829
17442832
33550096
18222538
18426857
17047048
12004076
34230460
23318261
33961781
12808024
21335603
12586829
17353276
11358837
28514442
20724477
16140212
12205091
20049704
16862177
11331613
32535973
15721254
14691445
15385570
10973499
15611064
17981124
28775317
12925778
26496610
17339318
30237125
20458141
20639890
17986458
19147576
28425505
11504942
22369643
18264140
16511565
12351678
14600153
30988076
17132228
|
PSMA8
|
PSMB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
971.0
|
0.97
|
STRING
|
36370105
|
PSMB5
|
PSMD6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
973.0
|
0.97
|
STRING
|
36370105
|
PSMB1
|
PSMD6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
974.0
|
0.97
|
STRING
|
36370105
|
COX5A
|
COX6B1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
975.0
|
0.97
|
STRING
|
36370105
|
PSMB1
|
PSMD3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
978.0
|
0.97
|
STRING
|
36370105
|
PSMD4
|
PSMD2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.98
|
0.98
|
HIPPIE
|
17646385
30479383
25036637
24256120
16990800
22863883
33961781
24121268
22939629
26344197
|
NDUFA9
|
NDUFV3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
981.0
|
0.98
|
STRING
|
36370105
|
PSMB5
|
PSMD11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
982.0
|
0.98
|
STRING
|
36370105
|
DCTN1
|
DCTN2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
982.0
|
0.98
|
STRING
|
36370105
|
PSMB1
|
PSMD13
|
â—¼ PHYSICAL_INTERACTION
|
|
|
983.0
|
0.98
|
STRING
|
36370105
|
PSMB5
|
PSMD3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
984.0
|
0.98
|
STRING
|
36370105
|
NDUFA5
|
NDUFS2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
985.0
|
0.98
|
STRING
|
36370105
|
NFKB1
|
RELB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
986.0
|
0.98
|
STRING
|
36370105
|
NDUFA5
|
NDUFV2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
988.0
|
0.98
|
STRING
|
36370105
|
TP53
|
MDM2
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.99
|
0.99
|
mint
|
17139261
5219401
|
PSMD6
|
PSMD3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.99
|
0.99
|
HIPPIE
|
18775730
17353931
22863883
33961781
28292943
22939629
26344197
|
PSMD6
|
PSMD4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.99
|
0.99
|
HIPPIE
|
17353931
16990800
33961781
30479383
22939629
26344197
|
PSMB5
|
PSMD12
|
â—¼ PHYSICAL_INTERACTION
|
|
|
990.0
|
0.99
|
STRING
|
36370105
|
PSMB5
|
PSMD2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
990.0
|
0.99
|
STRING
|
36370105
|
PSMA3
|
PSMD13
|
â—¼ PHYSICAL_INTERACTION
|
|
|
991.0
|
0.99
|
STRING
|
36370105
|
PSMD13
|
PSMD2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
991.0
|
0.99
|
STRING
|
36370105
|
PSMD2
|
PSMD6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
991.0
|
0.99
|
STRING
|
36370105
|
PSMD13
|
PSMD3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
991.0
|
0.99
|
STRING
|
36370105
|
PSMD4
|
PSMD6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
991.0
|
0.99
|
STRING
|
36370105
|
PSMD12
|
PSMD6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
991.0
|
0.99
|
STRING
|
36370105
|
PSMD13
|
PSMD6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
991.0
|
0.99
|
STRING
|
36370105
|
PSMA1
|
PSMD6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
991.0
|
0.99
|
STRING
|
36370105
|
PSMA3
|
PSMD6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
PSMD3
|
PSMD6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
PPARG
|
PPARGC1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
PSMD11
|
PSMD13
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
PSMD11
|
PSMD6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
PSMD12
|
PSMD13
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
PSMA1
|
PSMD13
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
DCTN2
|
DCTN4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
POLR2D
|
POLR2K
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
PSMD14
|
PSMD6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
993.0
|
0.99
|
STRING
|
36370105
|
EPAS1
|
VHL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
993.0
|
0.99
|
STRING
|
36370105
|
PSMD13
|
PSMD4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
993.0
|
0.99
|
STRING
|
36370105
|
PSMA3
|
PSMB5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
PSMB5
|
PSMD14
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
PSMB5
|
PSMD4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
PSMD13
|
PSMD14
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
PSMB1
|
PSMD11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
PSMA3
|
PSMD12
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
PSMB1
|
PSMB5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
NDUFA5
|
NDUFB9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
NDUFA9
|
NDUFB9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
PSMA3
|
PSMD3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
PSMA3
|
PSMD2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
PSMA3
|
PSMD11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
PSMB1
|
PSMD14
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
PSMA1
|
PSMD2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
PSMD2
|
PSMD3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
PSMD12
|
PSMD3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
PSMA1
|
PSMD3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
PSMD3
|
PSMD4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
PSMB1
|
PSMD12
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
PSMA1
|
PSMD12
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
POLR2D
|
POLR2E
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
PSMA1
|
PSMA3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
PSMA3
|
PSMD14
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
PSMA1
|
PSMB5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
PSMA1
|
PSMD14
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
PSMD14
|
PSMD2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
PSMD14
|
PSMD4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
PSMD14
|
PSMD3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
PSMD11
|
PSMD2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
PSMB1
|
PSMD2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
PSMD12
|
PSMD2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
PSMA1
|
PSMB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
PSMA1
|
PSMD11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
MDM2
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
PSMA3
|
PSMB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
PSMA3
|
PSMD4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
PSMD12
|
PSMD14
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
PSMD11
|
PSMD14
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
PSMD2
|
PSMD4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
PSMD11
|
PSMD3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
PSMB1
|
PSMD4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
NDUFA5
|
NDUFS3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
NDUFS3
|
NDUFV3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
NDUFS3
|
NDUFV2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
NDUFS6
|
NDUFV2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
NDUFS6
|
NDUFV3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
PSMD11
|
PSMD4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
PSMD12
|
PSMD4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
PSMA1
|
PSMD4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
PSMD11
|
PSMD12
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
POLR2E
|
POLR2K
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
POLR2B
|
POLR2D
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
POLR2A
|
POLR2D
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
POLR2A
|
POLR2B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
H2AX
|
ATM
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
11934988
15279782
12792649
11893489
10959836
|
H2AFX
|
ATM
|
â—¼ PHYSICAL_INTERACTION
|
|
|
105.0
|
1.0
|
ACSN
|
11283614
11331603
11571274
11850621
11877377
12086603
12202749
12234250
12556884
12607003
14614141
14988723
15136767
15140942
15175241
15211575
15242590
15279786
15375219
15377654
15385537
15459660
15485915
15496928
15498778
15549137
15655342
15798197
15964794
16163361
16332722
16449207
16531125
16713580
16805667
16818604
16858402
17055429
17102137
17116323
17116885
17296725
17303408
17384638
17582221
17660363
17965729
18001824
18001825
18006705
18087292
18171670
18171986
18212739
18398454
18469862
18524993
18543256
18558713
18583988
18584027
18590585
18678890
18809224
18995830
19151707
19202191
19217833
19270065
19282663
19342888
19362533
19490890
19622404
19654615
19686080
19772495
19793801
19892829
20021983
20027199
20051983
20064462
20160076
20691907
20713526
20723763
21376743
2191300
22657828
22743550
23030059
23082994
23161013
23253856
23847781
24036544
24050180
24089143
24095737
24709898
7575488
9407949
9488723
9721205
|
H2AFX
|
ATM
|
â—¼ SHARES_COMPLEX
|
|
|
105.0
|
1.0
|
ACSN
|
11283614
11331603
11571274
11850621
11877377
12086603
12202749
12234250
12556884
12607003
14614141
14988723
15136767
15140942
15175241
15211575
15242590
15279786
15375219
15377654
15385537
15459660
15485915
15496928
15498778
15549137
15655342
15798197
15964794
16163361
16332722
16449207
16531125
16713580
16805667
16818604
16858402
17055429
17102137
17116323
17116885
17296725
17303408
17384638
17582221
17660363
17965729
18001824
18001825
18006705
18087292
18171670
18171986
18212739
18398454
18469862
18524993
18543256
18558713
18583988
18584027
18590585
18678890
18809224
18995830
19151707
19202191
19217833
19270065
19282663
19342888
19362533
19490890
19622404
19654615
19686080
19772495
19793801
19892829
20021983
20027199
20051983
20064462
20160076
20691907
20713526
20723763
21376743
2191300
22657828
22743550
23030059
23082994
23161013
23253856
23847781
24036544
24050180
24089143
24095737
24709898
7575488
9407949
9488723
9721205
|
H2AFX
|
ATM
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
105.0
|
1.0
|
ACSN
|
11283614
11331603
11571274
11850621
11877377
12086603
12202749
12234250
12556884
12607003
14614141
14988723
15136767
15140942
15175241
15211575
15242590
15279786
15375219
15377654
15385537
15459660
15485915
15496928
15498778
15549137
15655342
15798197
15964794
16163361
16332722
16449207
16531125
16713580
16805667
16818604
16858402
17055429
17102137
17116323
17116885
17296725
17303408
17384638
17582221
17660363
17965729
18001824
18001825
18006705
18087292
18171670
18171986
18212739
18398454
18469862
18524993
18543256
18558713
18583988
18584027
18590585
18678890
18809224
18995830
19151707
19202191
19217833
19270065
19282663
19342888
19362533
19490890
19622404
19654615
19686080
19772495
19793801
19892829
20021983
20027199
20051983
20064462
20160076
20691907
20713526
20723763
21376743
2191300
22657828
22743550
23030059
23082994
23161013
23253856
23847781
24036544
24050180
24089143
24095737
24709898
7575488
9407949
9488723
9721205
|
ATM
|
MDM2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
54.0
|
1.0
|
ACSN
|
11331603
11438669
11804596
11877377
12086603
12556884
12607003
14988723
15136767
15140942
15175241
15459660
15485915
15798197
15867354
15964794
16163361
16332722
16581787
16713580
16731533
16805667
16858402
17102137
17116885
17296725
17303408
17384638
17582221
17713585
18006705
18048416
18469862
18511906
18583988
18716619
18756267
18995830
19151707
19282663
19342888
19357644
19490890
19622404
19788416
19793801
19793861
19841479
20019063
20051983
21376743
23847781
9168117
9858600
|
H2AFX
|
ATM
|
â—¼ REGULATES
|
✅
|
|
105.0
|
1.0
|
ACSN
|
11283614
11331603
11571274
11850621
11877377
12086603
12202749
12234250
12556884
12607003
14614141
14988723
15136767
15140942
15175241
15211575
15242590
15279786
15375219
15377654
15385537
15459660
15485915
15496928
15498778
15549137
15655342
15798197
15964794
16163361
16332722
16449207
16531125
16713580
16805667
16818604
16858402
17055429
17102137
17116323
17116885
17296725
17303408
17384638
17582221
17660363
17965729
18001824
18001825
18006705
18087292
18171670
18171986
18212739
18398454
18469862
18524993
18543256
18558713
18583988
18584027
18590585
18678890
18809224
18995830
19151707
19202191
19217833
19270065
19282663
19342888
19362533
19490890
19622404
19654615
19686080
19772495
19793801
19892829
20021983
20027199
20051983
20064462
20160076
20691907
20713526
20723763
21376743
2191300
22657828
22743550
23030059
23082994
23161013
23253856
23847781
24036544
24050180
24089143
24095737
24709898
7575488
9407949
9488723
9721205
|
ATM
|
BID
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
18662573
16122425
25077544
16122426
21113148
17525332
|
ATM
|
HIF1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
27245613
24681585
21095578
18971907
21095582
27027353
23573973
27068951
25956861
23707302
26942179
|
ATM
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
452.0
|
1.0
|
Omnipath
|
25301947
21720806
23549171
10713094
16501611
15077171
24886358
17570479
19375142
22028490
16916644
14712210
19303885
9407038
11927276
26700820
28356518
15226429
10723129
19788889
12064478
19705844
26673821
22179422
20931131
19062161
27030982
22891162
17157788
19056039
15758953
12049739
15361830
26620371
25865756
22615843
10196661
10656682
11313957
25088203
15140942
12519769
16319535
24469230
12776195
17234789
27511909
29238697
24608431
12927814
16783362
11875057
16436515
22778557
15181149
12702572
10500142
15178764
28842590
28145533
11591448
17855337
22726545
20206688
26824362
21317290
26104798
24704793
9765199
11314044
16906133
17174997
21593792
17967874
10771484
15585169
19625493
15178448
17596534
16288207
15048074
18353733
24057508
19535302
29344296
23708100
29872395
23705030
25043304
33761896
18431490
21404020
15024084
22559321
12151394
24078877
12080066
33982778
16893723
10958792
18289945
27183917
26337656
29170437
18765533
10744722
21748595
18056442
24820418
15489892
16390936
24086335
28140789
23091651
34523970
32001619
23418564
15279808
21317932
21188172
27559048
16818505
17616578
11551930
19010925
11709713
24711418
28654064
18339864
11173129
17486112
10570149
29774100
18381438
21994612
29558908
15258567
9372954
25860929
16858402
33692124
15775976
34107253
19923893
24958101
10436023
14752509
19962312
19071090
26438152
26093282
20123963
22444248
9843217
17525332
15456784
23533526
11780126
20353948
29290977
11096068
28102346
18855897
20372057
24395704
23890999
15725625
15806145
34103468
18345031
16997395
16293623
28477117
19828454
27630139
12071847
22002314
21315088
27177180
12645530
12890678
26113041
15794754
18560558
22099307
9885574
28903382
15665826
24877058
18332866
10611322
24380814
14871840
19934315
22975381
16489034
18406507
21440540
33687951
10608806
23892398
20730097
16914171
15782130
15177184
22055193
18490454
25867001
24349352
18045533
20663147
17535811
20506250
23982736
22375140
15700044
15279774
19266268
24358288
18697815
14729946
20637859
12242661
12771937
17371838
31940492
19409520
10528155
24037342
17257427
11121242
15310764
23148227
28915641
26928575
21423215
11865061
16949371
27810895
18449195
20711232
27389279
22213803
16713569
10446957
22797063
16478990
29048667
15489221
17241873
21187893
21441950
23907539
20005840
9733514
26244501
21614094
12082529
10467728
10714958
32061892
16636671
29147215
10673501
12091386
25202122
21465263
19544417
25823026
24078903
24038750
22198295
21480565
15177039
28182994
28208785
18674635
20183804
18818083
9925639
17712528
15254178
11483158
27940348
26675349
26261212
19717643
12606585
24559687
14871926
23150668
21329876
28153791
12518062
12767922
23824039
11711532
19251701
28118604
15078887
12393500
17456577
20976220
23380594
12519780
20810927
15533933
22420423
17108107
20145032
18032786
18785202
22037398
23184057
31968249
16729035
12588868
21614932
11546806
18614045
14757188
15029243
14968111
22649771
25512053
34496248
18604166
17609585
17976513
16223874
25433195
18985806
9363941
15159397
34282274
29301278
24505404
26056062
23577291
18272544
18715874
19536869
29334356
10801407
15155458
25201202
24376853
19907922
23525106
14643431
28340339
28051100
19085961
15212693
22201816
20026654
16322229
20080565
9733515
15632067
18672098
22577550
25691451
12637545
12548019
11672523
26984736
12324477
16552184
22084686
10864201
14744854
21532626
17118344
19482562
9561848
12511424
17668048
23358251
18511169
21460853
22022355
12939400
21415014
17292432
25651062
23168260
12111733
16648554
30361254
23678107
|
ATM
|
MDM2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
66.0
|
1.0
|
Omnipath
|
14654783
12383858
17936559
20651945
17303408
19816404
10611322
23150762
23277204
23386996
26416444
27258263
23002429
11331603
15865937
21556066
16163361
23708100
17570479
20514355
22264782
27177180
18265945
28690977
23847781
22264786
15140942
15964794
19788416
22624716
25201202
27462439
12607003
28050229
32350255
22649771
27956626
15459660
22976441
25247188
28904407
11877377
21859827
24534650
23405218
29290977
27568562
|
ATM
|
H2AX
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
197.0
|
1.0
|
Omnipath
|
27410735
28544233
16426903
28797244
9488723
23847653
30197789
21930799
18158901
21693595
18848500
22819196
15603757
16760673
17570479
24688021
24793032
27458206
16531125
22028490
30154456
19230794
23202908
25852739
19059218
26073471
22247744
28259974
29584802
25691887
19049966
20368801
26700820
29386061
28124509
20613862
27550454
20847938
27388041
27752097
23269287
24480460
22237206
20461094
20971043
26941327
18285803
21690091
15279774
23891287
25847270
24490130
25349305
26906421
20637859
26314960
15286739
27780918
20454618
30013081
28671946
25218945
23742011
26391293
23972723
23382699
26416514
27442013
20703100
24726884
26512707
27332952
29641431
25287622
26295265
14643438
29163809
25264544
19895790
26504743
26113859
27431324
28790385
18413980
21283714
21787120
20205745
19781914
25093845
27135971
23227178
22224778
20923785
20860841
24244154
23386996
30065307
16858402
11879731
28009280
23343929
20192759
22761798
26855420
24378750
20068231
20580718
14504478
24893124
29048667
25661368
26860083
26019182
20488183
28764946
22205726
23977391
18471973
19591958
28239143
20542002
17525332
20495376
18755145
23050241
17782711
11571274
19473884
28431265
25742493
18248856
17690115
20684759
26317467
21727091
24651472
25827888
27164092
28587922
20976184
30723510
20471486
23772364
29794999
11893489
19014481
20165693
26671524
16997395
20936109
26114388
23845989
15138496
22761813
23355489
27455285
28943310
21348461
19647519
23678292
23166506
28099474
29434792
25249630
25269479
27310012
15177039
22559321
26045162
20865059
22972376
21148072
26760771
21188122
22962268
22768044
26711340
20460517
27845910
28855246
|
NFKB1
|
BAX
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
6.0
|
1.0
|
ACSN
|
12676992
15613549
21725609
23178297
23572150
7834749
|
HIF1A
|
BAX
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
18366759
17558861
15706354
24349374
|
TP53
|
BAX
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
74.0
|
1.0
|
Omnipath
|
11278953
12203124
16931621
9582019
17693666
11118038
12433990
11395510
8183578
11429705
10400708
15242522
11423991
19067706
24336083
18381427
22732402
15988033
16341121
10935506
10094833
16215989
17280505
10744634
12851404
20673369
15851483
8845569
10559267
12168779
11850816
19505426
8564971
11756653
19054058
15566940
12173040
17690113
8635454
18034190
10510469
10101800
11335718
23100276
9400998
9445173
9582400
24098340
22532570
9122197
11420692
11104574
15679092
11748232
12560513
11928223
20400479
20546728
17145718
20567883
20840522
18172861
10566557
10777477
7834749
12806965
17521288
19242108
9000137
21859835
|
RELA
|
BAX
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
18034190
18158998
20056115
|
BID
|
BAX
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
21.0
|
1.0
|
Omnipath
|
20956295
17289999
25241761
19968986
15574335
10629050
19062087
10949027
12242151
23374347
14730312
17520191
8918887
|
AKT1
|
BAX
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
26763134
14766748
15642728
17525161
|
TP53
|
BAX
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
14963330
16151013
7834749
|
BAX
|
CYCS
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
9461218
10629050
20709625
9843949
11326099
12232790
|
BID
|
HSP90B1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
ACSN
|
14687661
18360008
23430059
23850759
|
BID
|
HSP90B1
|
â—¼ PROTEIN_INTERACTION
|
|
|
4.0
|
1.0
|
ACSN
|
14687661
18360008
23430059
23850759
|
HIF1A
|
BID
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
66.0
|
1.0
|
ACSN
|
10102273
10428030
10428780
10435632
10804084
10823814
11557773
11559532
11744734
11756417
11884613
12402042
12676992
12743597
14672622
14684737
14699081
14762718
15024076
15059920
15199147
15240700
15312748
15369676
15379897
15545625
16110315
16126909
16127144
16517405
16517406
16585195
16782875
16888645
17143338
17418790
17533374
17785433
18054315
18056423
18158893
18718909
19211554
20028863
20427344
20535745
20855962
21051947
21765015
22006996
22841746
22850421
22988108
24006507
25043024
25103413
25732824
7493931
7500013
7508926
8089148
8702901
8955077
9486205
9525945
9707622
|
TP53
|
BID
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
12402042
16151013
18574470
|
CSNK1E
|
BID
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
11583622
12598529
20356928
|
TP53
|
BID
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
15240700
12402042
18431400
15024076
|
TP53
|
BTG2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
10321740
15741235
19031424
19551855
21394211
16581545
|
AR
|
BTG2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
21172304
20610535
16281084
|
TP53
|
BTG2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
8944033
10669755
|
FOXO3
|
CDKN2D
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
9308237
17936558
18644865
19380174
10783894
11283613
16288288
17873901
20673124
11094066
21708191
17646672
15084260
15509806
21613825
17940099
11994454
11154281
|
CEBPG
|
APOB
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
8557677
1545795
2161847
2258060
|
CEBPG
|
IL6
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
17.0
|
1.0
|
Omnipath
|
12177065
22389450
9655919
12219016
15389813
9621116
12200447
14754879
9950766
12626566
15158360
22558159
14600152
16798734
12215492
12115737
19782405
|
CSNK1E
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
10606744
11709713
10951572
10734067
16713569
11551930
10747897
10673501
11883897
|
HSPA5
|
EIF2AK3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
17145710
28534368
18624755
11907036
31226023
|
HIF1A
|
FOXM1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
22831955
19097132
|
FOXM1
|
VEGFA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
18974115
21860419
19813088
|
FOXM1
|
SKP2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
16585184
16314512
|
AKT1
|
FOXO3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
7.0
|
1.0
|
ACSN
|
11154281
11715018
11923280
15169778
17680028
20214616
20398329
|
HIF1A
|
FOXO3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
66.0
|
1.0
|
ACSN
|
10102273
10428030
10428780
10435632
10804084
10823814
11557773
11559532
11744734
11756417
11884613
12402042
12676992
12743597
14672622
14684737
14699081
14762718
15024076
15059920
15199147
15240700
15312748
15369676
15379897
15545625
16110315
16126909
16127144
16517405
16517406
16585195
16782875
16888645
17143338
17418790
17533374
17785433
18054315
18056423
18158893
18718909
19211554
20028863
20427344
20535745
20855962
21051947
21765015
22006996
22841746
22850421
22988108
24006507
25043024
25103413
25732824
7493931
7500013
7508926
8089148
8702901
8955077
9486205
9525945
9707622
|
MDM2
|
FOXO3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
14.0
|
1.0
|
ACSN
|
11715018
11779693
11923280
14761977
15024084
15084260
15169778
15876864
16307918
17110379
17158541
19321440
20679392
9450543
|
FOXO3
|
AKT1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
15987244
10358075
10102273
12857750
|
FOXO3
|
FASLG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
11756562
20051626
15895074
20371612
10102273
14701673
20671123
19690465
|
FOXO3
|
SOD2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
24068327
15674333
12239572
15308628
24339251
|
FOXO3
|
SIRT1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
23525956
20816089
15604409
23262029
|
FOXO3
|
AKT1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
19424579
23517348
21752881
22539004
11278373
|
FOXO3
|
CCNG2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
21532621
18226221
1235163414966295
14966295
16493026
|
FOXO3
|
AR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
16061480
17522055
18687691
|
STK4
|
FOXO3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
27769056
22898666
18394876
28521392
16751106
18985696
|
CHUK
|
FOXO3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
15084260
23691078
20300203
|
SGK3
|
FOXO3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
10102273
11154281
|
SIRT1
|
FOXO3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
12.0
|
1.0
|
Omnipath
|
24003218
14976264
14980222
15126506
21713995
15917664
|
IKBKE
|
FOXO3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
15084260
22531926
23691078
20300203
|
AKT1
|
FOXO3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
64.0
|
1.0
|
Omnipath
|
19951971
11756412
11953455
11923280
20452955
21798082
20398329
21329882
10217147
11154281
11994454
23331499
10995739
19216069
20214616
11463845
21775285
20068231
9829964
17570479
10102273
18593906
17646672
16680151
18988627
21621563
15169778
17522590
25241761
23109003
11715018
19188143
15023346
17680028
26192618
11864996
|
FOXO3
|
PIK3CA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
18644865
10783894
16288288
20673124
11094066
17646672
15509806
11994454
11154281
|
FOXO3
|
FASLG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
14976264
18644865
10783894
16288288
20673124
11094066
10102273
17646672
16865280
15509806
11994454
11154281
|
FOXO3
|
SOD2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
18280257
12239572
10492402
15766528
|
AKT1
|
FOXO4
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
15987244
10358075
10102273
12857750
|
SIRT1
|
FOXO4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
23331499
15126506
10102273
|
AKT1
|
FOXO4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
58.0
|
1.0
|
Omnipath
|
11756412
20452955
21798082
20398329
15538382
10217147
23331499
19216069
20214616
11463845
23180781
9829964
11313479
10102273
10518537
14690436
16680151
17646672
18988627
17522590
11896584
16272144
11689711
17680028
21620960
19664994
11864996
|
GRB2
|
KL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
11353842
9632781
14534538
9182757
|
GRB2
|
VEGFA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
52.0
|
1.0
|
ACSN
|
10022831
10086337
10567412
10811803
10849428
10982827
11166270
11447289
11449354
11532940
11777939
11960372
12175651
12393695
12629515
12640133
13678960
15099563
15111329
15501236
15520864
15567848
15573129
15574420
16002046
16076871
16572188
16582911
16887996
17086423
17496910
17673906
17883421
19414323
19449109
21372296
21378271
22064427
22461508
23390297
23896411
24217602
24346288
24670066
25922287
26201938
26552706
8551221
8837607
9157999
9570538
9753319
|
GRB2
|
VEGFA
|
â—¼ SHARES_COMPLEX
|
|
|
52.0
|
1.0
|
ACSN
|
10022831
10086337
10567412
10811803
10849428
10982827
11166270
11447289
11449354
11532940
11777939
11960372
12175651
12393695
12629515
12640133
13678960
15099563
15111329
15501236
15520864
15567848
15573129
15574420
16002046
16076871
16572188
16582911
16887996
17086423
17496910
17673906
17883421
19414323
19449109
21372296
21378271
22064427
22461508
23390297
23896411
24217602
24346288
24670066
25922287
26201938
26552706
8551221
8837607
9157999
9570538
9753319
|
HRAS
|
GRB2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
11.0
|
1.0
|
Reactome
|
19946327
11429702
11157491
18757403
21666749
21711248
18381441
19103595
21160078
9857065
20179196
|
GRB2
|
VEGFA
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
52.0
|
1.0
|
ACSN
|
10022831
10086337
10567412
10811803
10849428
10982827
11166270
11447289
11449354
11532940
11777939
11960372
12175651
12393695
12629515
12640133
13678960
15099563
15111329
15501236
15520864
15567848
15573129
15574420
16002046
16076871
16572188
16582911
16887996
17086423
17496910
17673906
17883421
19414323
19449109
21372296
21378271
22064427
22461508
23390297
23896411
24217602
24346288
24670066
25922287
26201938
26552706
8551221
8837607
9157999
9570538
9753319
|
GRB2
|
MAP2K7
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
32.0
|
1.0
|
ACSN
|
10086337
10567412
10811803
10982827
11274345
11447289
11756498
11777939
12040186
12175651
12640133
12738796
14585353
15567848
15574420
15863030
16102570
16582911
16887996
17496910
17673906
18000759
18855897
19151919
19449109
19568798
21614932
24027568
26552706
27331412
7510700
8551221
|
ERBB2
|
GRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
27.0
|
1.0
|
Omnipath
|
31980649
9756944
21278786
16273093
24189400
11173924
9710588
24658140
11606575
14967450
17875712
16713569
16729043
|
MET
|
GRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
9660480
15546961
22128289
12475979
11063574
7511210
11439336
8662889
|
IRS2
|
GRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
7559579
11788580
10358772
11305324
9852124
|
AP2A1
|
GRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
17145710
12577067
|
GRB2
|
HRAS
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
17496910
16713569
17673906
11352655
|
IKBKE
|
RELA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
24.0
|
1.0
|
Omnipath
|
28317833
12842894
16046471
20188669
15128824
17561400
17003035
30223576
15485852
10521409
15489227
15849198
16407239
26025205
15212693
12767944
|
KAT5
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
17188038
15310756
18280244
16601686
|
KAT5
|
AR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
11591700
10364196
19150978
11994312
16713569
|
KAT5
|
APP
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
21832049
12032152
16223726
14699153
15331662
15044485
|
AKT1
|
MDM2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
7.0
|
1.0
|
ACSN
|
11154281
11715018
11923280
15169778
17680028
20214616
20398329
|
TP53
|
MDM2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
201.0
|
1.0
|
Omnipath
|
23150757
20948295
10871862
10914734
21422812
21957016
14532965
22290440
20663877
20547751
11591713
24339722
11840331
22223137
16492744
15843377
22948151
7888679
20156675
21217645
22180176
8319905
9707425
15831521
17690113
9649502
10688649
9194564
15917661
15090541
20837136
8187772
10788589
17907153
15192123
8440237
11964305
16510138
10856296
15580300
7624148
12208736
21211512
16624812
17848574
11245471
21637567
20588255
10562557
9525742
9270029
16479015
19941079
14602726
15024021
18814047
20036872
10718212
18852133
12374749
18397889
25016801
12755686
22081073
22245141
23365201
8957072
22197810
15856024
20703075
23483203
9645455
19648117
20331637
22301280
14743206
23982177
9486848
15734740
19638633
19671680
17310983
10469568
20659896
10072445
21097889
17237821
11748232
11085543
21750655
16337599
21295542
1614537
9815889
9070662
16585169
9472631
17936559
17139261
11328884
12887889
20858413
9858609
14610316
20080970
19505873
11313463
15684615
18359851
18783169
16202543
9267820
12235242
14990790
15851483
7587074
18336191
21478269
17043642
15361831
18025460
23612020
10208414
11756653
24389645
9071998
9430645
9400998
9371494
23149414
22532570
9271120
10777217
22383580
18781178
12606552
14514686
17318220
11127813
16571800
19085961
9207798
10891494
10065155
11593391
14570892
12902982
19649205
20124454
17390010
19955655
12138177
19663772
23581014
15908423
10321740
23150759
19837670
10348346
18632610
9294611
11956627
12750288
12851404
8313378
9135153
15735665
7958853
8247544
9535786
16501602
18566224
8910340
11046142
9405685
7936649
12173040
17329361
21451571
14704432
23874713
18333294
19541936
22787160
18585004
22085928
12080472
7651818
11179471
10949923
19428175
15592502
8413278
11714701
10566557
18583933
9681831
15550242
15007388
19590512
|
AKT1
|
MDM2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
60.0
|
1.0
|
Omnipath
|
11756412
11923280
20856200
20452955
20398329
18332867
19664995
10217147
11154281
19216069
20214616
11463845
19166854
15527798
9829964
17570479
16680151
17646672
12145204
15169778
15140942
25241761
11715018
25209720
17680028
21930127
11504915
29311840
15574337
23397142
|
MDM2
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
559.0
|
1.0
|
Omnipath
|
20657550
30005830
17616658
9529249
10321734
33650658
9724739
24462112
24621507
15933712
23826318
24667498
22948151
22653443
23776060
25313037
25241761
19303885
16857591
23246961
19033382
20591651
21149449
25417702
15122315
16579792
27543608
29670376
12208736
17848574
26673821
25277184
23443559
23318437
21060154
15210108
19805293
8875929
8058315
21471462
17879958
25362358
23169665
22301280
21584881
20124408
10980696
26876197
17310983
17380154
15058298
24567357
18665269
30109812
25637791
18467333
22337874
22227409
22389628
15242646
22510990
15950904
15001357
19483087
26540344
14559824
21986495
26556313
20708156
19901969
33765973
32528731
11562347
10202144
22374672
10722742
22083959
21965653
17098746
19234109
30679555
16107876
12690203
22525275
19071110
28542145
12620407
20837658
27129163
9131587
24240685
27031960
10681559
19305137
11744695
19188367
16023600
24659749
17347673
12944468
20395212
22084066
20639885
21454483
12897156
16432196
10347217
10706102
11178989
20174603
16751805
15542844
12842086
11431470
11384992
25739118
15064742
23402884
27462439
16905769
22124327
27215386
12867035
22588298
27336364
14702041
16152627
23776465
22262183
21132010
19411846
18309296
23483203
11709713
18981217
14612427
22920093
23671280
24980433
27905468
25168242
21750659
26238070
22737255
23609977
27282385
20847049
20705607
21075307
28082682
17297477
11697899
17936559
24361594
19098711
15469934
34591612
24998844
16212962
11094089
12915590
17116689
11713288
15144954
23201157
10608892
17591690
25156994
17301054
22444248
26883110
26001071
19160491
22157679
24413661
19357310
23802716
15280377
21317885
11597128
19579266
25624478
18061646
21088494
9223638
10435614
31177307
11331603
22391559
20570896
19941302
9278461
18485870
15604276
18566590
12612087
11046142
14704432
26186194
10935507
16173922
14596917
17159902
25543083
19656744
15848166
18316739
22266868
17056014
19255450
21561866
19590512
11839577
22991965
22266850
24200963
11285227
11713287
22975381
19081178
20660730
26475964
16678796
23261415
20173098
17666403
25464845
32427887
23252402
17438265
20959462
22659184
17470788
22912717
17080083
15247280
19332559
17989425
16870621
18813780
20235143
11278372
10562557
25609649
10561590
19411066
17908790
19568783
7926727
21925390
21988832
24127580
18604177
14499615
17371838
17525743
33061576
21887275
26578655
21084564
16861890
20694676
12552135
22914926
17363365
24643130
1614537
22916255
12381304
34992144
12167711
19857530
15053879
10889512
11486026
22103682
16713569
17110336
17426254
10640350
21316347
21478269
15154850
12529318
16595680
16414131
19597489
23880345
27893708
7686617
27811966
17318220
29997244
27308622
19166840
35044719
16159876
24314634
15313915
25283148
22032989
24926618
18172499
19837670
16215989
23134341
26908445
9824166
18451149
21170087
23572512
21465263
22807444
15013777
16845383
10488081
23946421
11714701
25384516
22474335
25312347
23370271
23150757
18541670
22318540
11925449
21572037
24488098
32066565
17268548
20542919
11572869
16338390
21857681
23150668
19223463
20234175
20484049
11070080
20591429
22575647
11351297
16624812
22411991
20588255
17369817
11223036
15908921
9582019
25103245
17302414
21071676
9450543
31968249
34562520
18332869
14671306
21084285
27856536
30464405
26882543
21726810
33020477
21261729
21268072
12426395
16964247
20659896
19106616
22331460
23728348
10827196
22524527
21098709
9363941
17139261
20080206
14517261
22487680
31652301
17290220
27106262
16866370
24207125
28223335
9271120
15550400
7689721
26350565
10196247
27807478
10766163
15558054
35371302
26203195
29487367
25512388
25954860
18223694
15824742
24842904
14741215
16055726
22085928
32894144
18234963
17875722
18815136
15295102
15308643
15358376
22819825
15094782
|
MDM2
|
HIF1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
15880652
25535359
12606552
25447306
17234751
19696166
10640274
|
MDM2
|
AR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
11.0
|
1.0
|
Omnipath
|
17974989
26411689
27835608
26973243
15640443
12145204
|
SIRT1
|
PPARGC1A
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
ACSN
|
15205477
15744310
15989956
18687677
19590512
19960022
|
RELA
|
SIRT1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
20617556
15152190
24064732
|
SIRT1
|
PPARGC1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
23142079
21633182
19553684
|
SIRT1
|
PPARGC1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
15744310
20640476
24003218
19553684
|
SIRT1
|
RELB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
19408108
15152190
21245135
18193389
|
SIRT1
|
RELA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
19408108
25217963
15152190
21081649
|
SIRT1
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
21.0
|
1.0
|
Omnipath
|
18235502
11672523
18235501
15205477
35931247
15989956
17964266
25280219
19047049
16713569
19960022
21245319
12006491
19590512
|
AR
|
SMARCA2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
20610535
17721441
|
NFKB1
|
SOD2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
7.0
|
1.0
|
ACSN
|
10492402
12239572
15766528
18280257
21725609
23178297
23572150
|
TP53
|
SOD2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
23784082
20739073
10969820
16740634
22009531
24047462
20061391
15059885
20601193
11313974
|
RELA
|
SOD2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
16850160
17085785
15330761
18779124
24047462
11880364
20061391
10760955
19507253
14515147
|
NFKB1
|
SOD2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
17085785
15330761
24068327
18779124
17652337
11880364
19507253
14515147
|
NFKB1
|
SOD2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
18280257
12239572
10492402
15766528
|
FOXL2
|
SOD2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
19010791
17360647
|
HIF1A
|
TP53
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
12542982
17390008
9537326
15780936
11696352
10469629
17236590
20706634
15629713
11007955
|
AHR
|
TP53
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
17070097
15111621
11191113
20478272
|
RELA
|
TP53
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
18269916
10348347
11032029
8051093
20061391
15155458
21332394
9890939
21887328
|
NFKB1
|
TP53
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
10348347
11032029
8051093
12145335
20097177
|
TP53
|
CHUK
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
15469934
11557753
17434128
|
TP53
|
VEGFA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
13.0
|
1.0
|
Omnipath
|
8108142
20639906
9377555
21325822
16684540
9833779
10910082
16835303
23449391
8521408
15860260
11971180
11559575
|
TP53
|
AR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
17202838
18084622
18945670
11504717
|
TP53
|
HRAS
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
21552926
9662334
11127813
21552928
|
TP53
|
PRODH
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
16303758
18279664
18794809
23861960
|
TP53
|
AKT1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
12485897
18661553
19763735
|
TP53
|
FASLG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
17196791
9889415
20393600
9841917
|
TP53
|
CRYAB
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
19343786
24859470
19777343
21556774
19799611
|
AURKA
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
50.0
|
1.0
|
Omnipath
|
24173284
22864622
25217103
24089029
16713569
19413330
25848977
17999753
23565200
25333414
23201157
16552184
10884347
1956339
26186194
29455673
15469940
15749021
18974145
21502403
17287340
28043820
22396649
92065884
12198151
27933271
22852086
12064478
30266789
25398437
17259342
22350019
25634113
14702041
|
MAPK13
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
15187187
19436832
15140942
10581258
20506250
21614932
16393692
24818748
11274345
|
PRKCA
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
18812399
9935181
15659650
9315650
19933256
16713569
9571186
1454855
|
TP53
|
HIF1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
9537326
16713569
12124396
15629713
16882692
|
COX7C
|
COX5B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
ACSN
|
11389896
15119951
16051147
17418790
19625251
8194600
|
COX5A
|
COX5B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
ACSN
|
11389896
15119951
16051147
17418790
19625251
8194600
|
COX6C
|
COX5B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
ACSN
|
11389896
15119951
16051147
17418790
19625251
8194600
|
COX7C
|
COX5B
|
â—¼ SHARES_COMPLEX
|
|
|
6.0
|
1.0
|
ACSN
|
11389896
15119951
16051147
17418790
19625251
8194600
|
COX5A
|
COX5B
|
â—¼ SHARES_COMPLEX
|
|
|
6.0
|
1.0
|
ACSN
|
11389896
15119951
16051147
17418790
19625251
8194600
|
COX6C
|
COX5B
|
â—¼ SHARES_COMPLEX
|
|
|
6.0
|
1.0
|
ACSN
|
11389896
15119951
16051147
17418790
19625251
8194600
|
COX7C
|
COX5B
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
ACSN
|
11389896
15119951
16051147
17418790
19625251
8194600
|
COX6C
|
COX5B
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
ACSN
|
11389896
15119951
16051147
17418790
19625251
8194600
|
NFATC1
|
CALM1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
8576111
8631904
10860980
9727000
8799126
|
NFKB1
|
BECN1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
4.0
|
1.0
|
ACSN
|
19289499
21725609
23178297
23572150
|
COX5A
|
COX7C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
ACSN
|
11389896
15119951
16051147
17418790
19625251
8194600
|
COX7C
|
COX6C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
ACSN
|
11389896
15119951
16051147
17418790
19625251
8194600
|
COX5A
|
COX7C
|
â—¼ SHARES_COMPLEX
|
|
|
6.0
|
1.0
|
ACSN
|
11389896
15119951
16051147
17418790
19625251
8194600
|
COX7C
|
COX6C
|
â—¼ SHARES_COMPLEX
|
|
|
6.0
|
1.0
|
ACSN
|
11389896
15119951
16051147
17418790
19625251
8194600
|
COX5A
|
COX7C
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
ACSN
|
11389896
15119951
16051147
17418790
19625251
8194600
|
HIF1A
|
VEGFA
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
19.0
|
1.0
|
ACSN
|
10804084
16110315
16127144
17533374
20427344
20535745
20855962
21051947
21372296
21765015
22006996
22461508
22850421
22988108
23390297
24006507
25043024
25103413
25732824
|
IRAK4
|
VEGFA
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
25.0
|
1.0
|
ACSN
|
11274345
11964313
12620219
12682231
12907458
14607900
14660645
15749884
15749903
16127449
16243976
16413922
16713974
16878026
17404308
17485448
17704786
18633355
20547845
21372296
21826665
23508573
23681101
23811849
9743347
|
VEGFA
|
RELB
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
24.0
|
1.0
|
ACSN
|
10022831
11166270
11960372
12629515
13678960
15099563
15111329
15501236
15520864
15573129
16002046
16572188
17086423
19414323
21372296
22064427
22461508
23390297
24346288
26201938
8837607
9157999
9570538
9753319
|
NFKB1
|
VEGFA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
18184402
17673602
16684540
15517885
12160329
15856023
18056465
20538607
17407600
20103608
|
VHL
|
VEGFA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
12.0
|
1.0
|
Omnipath
|
12539169
8625303
9572397
9370235
10581162
19801654
12912922
10189987
9689663
7533661
10804089
8855222
|
RELA
|
VEGFA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
18184402
17673602
16684540
15517885
12160329
15856023
18056465
20538607
17407600
20103608
|
SMAD3
|
VEGFA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
15188178
18952601
20631490
22740248
21057546
15629128
11486006
15191565
|
AR
|
VEGFA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
16007189
23369005
18768969
18612129
15003169
|
HIF1A
|
VEGFA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
186.0
|
1.0
|
Omnipath
|
20303950
17085645
22609851
12697836
17557905
15140752
17431122
17486380
11866451
20453883
8756616
18027712
10702253
11678207
19046997
19491109
20127031
20307196
15315159
11359907
18233956
12032158
19502554
9178256
15956714
23060442
11350893
15930297
15207747
19074414
20660740
20489156
17089387
15735682
16506055
9746763
21793044
20436213
22789427
21814878
17053163
18835464
18072084
15983061
11749701
20875806
18432192
18471962
15039660
16750526
17322369
16052307
12433987
21447827
16682453
16971129
21258402
20027628
12542982
17272396
20574527
14712484
16865543
17916562
19664474
23354733
18060642
12570801
9235919
22903062
18563715
12154035
12612059
20599538
18572865
21187066
10837481
16596228
12963476
19828020
15169887
15156561
20232316
16969516
15111179
15342781
15475194
9398602
11001829
11191064
10882714
8387214
15191799
12820439
17413038
19111391
16854277
12509854
23404377
16900513
24347168
18021292
17947829
22771629
18295594
15774498
12205045
17498666
11007955
14699103
21145972
16618748
18322419
16540671
20724477
16778202
9393757
11549290
17065555
15315937
18024476
21343542
15705785
10987301
22306343
23086815
16774940
19420388
15050899
19759417
18289162
10415537
15277220
16818499
16982770
24464787
19238077
23028984
11056102
15838297
16301840
18578647
18702304
19020709
19564336
17461470
16515634
20043814
15806152
19336759
22750006
23185615
17470361
15746177
17889387
18339855
15890092
15663958
17704802
10477681
12052835
15382039
11707426
12855680
12023962
20432243
10611972
19819950
9359410
10640274
12393646
16311927
21435239
16357173
21731766
16543242
17481912
20449875
14602779
17167225
11486006
18294451
22076197
17999410
|
EPAS1
|
VEGFA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
26.0
|
1.0
|
Omnipath
|
15156561
15192019
19010893
15191799
19080330
20061373
9113979
16900513
20574527
10531360
21057546
21145972
11350893
16778202
23213445
11301389
20807755
9746763
9665461
11751212
12750296
24062466
11912213
16920734
17322369
|
HIF1A
|
VEGFA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
20.0
|
1.0
|
Omnipath
|
7768934
11528470
9278421
17987801
16716598
12080085
10403805
16887934
7539918
1823643
12829734
13130303
15451019
9746763
8943284
15369676
9159130
11901189
22952674
11566883
|
CHUK
|
MAP3K7
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
Reactome
|
20300203
9744859
17047224
11460167
17496917
14514672
|
RIPK2
|
MAP3K7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
18079694
17079228
17947236
10702308
17348859
17965022
15075345
|
MAP3K7
|
CHUK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
24.0
|
1.0
|
Omnipath
|
17145710
14960582
16893890
15836773
33895773
12547194
25241761
24911653
2547194
9742107
18949366
11274345
20200282
20194509
10094049
18855897
10187861
|
MAP3K7
|
MAP2K7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
23331499
17110930
17709393
25241761
9890973
|
SMAD3
|
IL6
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
14754879
12672795
18804287
12853969
|
SMAD3
|
PPARG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
21836474
21926264
12457461
12524424
|
AKT1
|
SMAD3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
23331499
25241761
15104092
16362038
21071413
18988627
26297431
15048128
|
SMAD3
|
AR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
17.0
|
1.0
|
Omnipath
|
23331499
11248024
11280774
12226080
16713569
11707452
|
IRAK4
|
IL6
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
25.0
|
1.0
|
ACSN
|
11274345
11964313
12620219
12682231
12907458
14607900
14660645
15749884
15749903
16127449
16243976
16413922
16713974
16878026
17404308
17485448
17704786
18633355
20547845
21372296
21826665
23508573
23681101
23811849
9743347
|
IRAK4
|
NLRP3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
25.0
|
1.0
|
ACSN
|
11274345
11964313
12620219
12682231
12907458
14607900
14660645
15749884
15749903
16127449
16243976
16413922
16713974
16878026
17404308
17485448
17704786
18633355
20547845
21372296
21826665
23508573
23681101
23811849
9743347
|
HIF1A
|
IL6
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
21.0
|
1.0
|
ACSN
|
10804084
15749903
16110315
16127144
16243976
16413922
17485448
17533374
20427344
20535745
20855962
21051947
21765015
22006996
22850421
22988108
24006507
25043024
25103413
25732824
9743347
|
RELA
|
IL6
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
114.0
|
1.0
|
Omnipath
|
26596471
19124729
10373597
9523851
23595969
28270510
21537341
17982049
15226358
18243142
12200447
20371366
24664372
23874122
14532843
18942706
10975857
21278793
10469356
22547075
17490702
11459775
23335080
10569191
19707556
19687301
7499267
8290595
23857586
24676671
18061164
11058167
12887736
15013753
15158360
22661093
20935672
20511231
17350185
10903137
16112536
27413250
21810609
16984731
16166627
18469854
12881425
24012417
23386688
22105366
8752656
12176740
27371733
22578249
18057724
20351184
10329846
19164127
10542237
11564778
20221401
15517885
19122653
20534538
7876168
27211851
9516466
18996370
8824277
18310089
21104991
25888873
12359431
11327783
20066113
20100571
19703987
19469019
21106671
16960103
18502099
16043358
21996739
20650996
22021035
11120852
12672795
12058956
18483242
22189669
14976218
17495236
11007957
21131967
11975924
27337441
9182853
10963848
17040605
11504280
15756023
10823821
17932106
19966855
20696864
12177065
8679226
9199307
17196927
20457835
21098092
17532054
|
HIF1A
|
IL6
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
17548584
20003295
21258402
15913932
18791496
|
AR
|
IL6
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
12237244
8824277
19074897
11049111
17374439
11410519
20610535
19363165
|
NFKB1
|
IL6
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
71.0
|
1.0
|
Omnipath
|
17513725
18061164
12058956
24337575
19124729
15611045
11058167
9523851
15517885
12887736
15158360
7876168
17495236
25549935
17982049
15241416
18243142
9516466
2405250
18996370
8824277
18310089
24664372
15749903
10903137
16112536
14532843
11327783
18942706
11975924
20066113
16984731
10975857
11160296
19703987
22895549
10963848
10469356
22547075
17040605
11459775
17490702
19469019
8247545
11504280
15756023
10569191
10823821
20696864
12907458
19707556
16043358
11035101
12176740
11302724
8679226
8725624
22578249
8752656
17196927
17532054
12727841
18057724
7499267
10329846
9199307
9502421
19164127
11120852
24676671
11098847
|
EIF4E
|
HIF1A
|
â—¼ UP_REGULATES
|
✅
|
+
|
16.0
|
1.0
|
ACSN
|
10403805
11566883
12080085
12829734
13130303
15451019
15563472
16887934
1823643
7539918
8943284
9155017
9159130
9278421
9746763
9878069
|
PRKCA
|
EIF4E
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
1911648
8662663
2355012
12897141
9155017
17570479
11723111
95301551
11463832
9878069
|
HRAS
|
PIK3CB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
31135801
24897931
8665852
17998941
11136978
21779505
8052307
12121613
1716764
26085527
21779497
12094235
|
HRAS
|
MAP2K2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
Reactome
|
15035987
21779496
24957944
22510884
23352452
25907612
|
HRAS
|
PIK3CD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
9069260
9113989
9235916
21779497
11739523
10545207
|
HRAS
|
PIK3CA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
20.0
|
1.0
|
Omnipath
|
9069260
9113989
8052307
24412244
17540175
9931431
11313862
14724584
10592173
9150145
8665852
10783161
|
PRKACA
|
RAP1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
8463283
9867809
|
NDUFB9
|
NDUFA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFA1
|
NDUFV2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFA1
|
NDUFV3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFA1
|
NDUFS3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFA1
|
NDUFA9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFA1
|
NDUFS6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFA1
|
NDUFC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFA1
|
NDUFA5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFA1
|
NDUFS2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFB9
|
NDUFA1
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFA1
|
NDUFV2
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFA1
|
NDUFS3
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFA1
|
NDUFA9
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFA1
|
NDUFS6
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFA1
|
NDUFV3
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFA1
|
NDUFS2
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFA1
|
NDUFC1
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFA1
|
NDUFA5
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFB9
|
NDUFA5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFS3
|
NDUFA5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFV2
|
NDUFA5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFS2
|
NDUFA5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFV3
|
NDUFA5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFC1
|
NDUFA5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFA5
|
NDUFA9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFA5
|
NDUFS6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFS3
|
NDUFA5
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFB9
|
NDUFA5
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFS2
|
NDUFA5
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFC1
|
NDUFA5
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFV3
|
NDUFA5
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFV2
|
NDUFA5
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFA5
|
NDUFS6
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFA5
|
NDUFA9
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFV2
|
NDUFA9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFS3
|
NDUFA9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFB9
|
NDUFA9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFS2
|
NDUFA9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFC1
|
NDUFA9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFV3
|
NDUFA9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFS6
|
NDUFA9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFA9
|
NDUFS3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
1.0
|
STRING
|
36370105
|
NDUFA9
|
NDUFS6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
1.0
|
STRING
|
36370105
|
NDUFA9
|
NDUFS2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
1.0
|
STRING
|
36370105
|
NDUFA9
|
NDUFV2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
1.0
|
STRING
|
36370105
|
NDUFV2
|
NDUFA9
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFV3
|
NDUFA9
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFS3
|
NDUFA9
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFB9
|
NDUFA9
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFC1
|
NDUFA9
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFS6
|
NDUFA9
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFS2
|
NDUFA9
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFB9
|
NDUFS3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFB9
|
NDUFV3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFB9
|
NDUFC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFB9
|
NDUFS6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFB9
|
NDUFV2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
15.0
|
1.0
|
ACSN
|
12847084
15186778
15526035
15807660
16186509
16200211
16218961
17344420
18199748
18360008
18485875
19131594
19509052
20025615
20816094
|
NDUFB9
|
NDUFS2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
15.0
|
1.0
|
ACSN
|
12847084
15186778
15526035
15807660
16186509
16200211
16218961
17344420
18199748
18360008
18485875
19131594
19509052
20025615
20816094
|
NDUFB9
|
NDUFV3
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFB9
|
NDUFS6
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFB9
|
NDUFV2
|
â—¼ SHARES_COMPLEX
|
|
|
15.0
|
1.0
|
ACSN
|
12847084
15186778
15526035
15807660
16186509
16200211
16218961
17344420
18199748
18360008
18485875
19131594
19509052
20025615
20816094
|
NDUFB9
|
NDUFS3
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFB9
|
NDUFS2
|
â—¼ SHARES_COMPLEX
|
|
|
15.0
|
1.0
|
ACSN
|
12847084
15186778
15526035
15807660
16186509
16200211
16218961
17344420
18199748
18360008
18485875
19131594
19509052
20025615
20816094
|
NDUFB9
|
NDUFC1
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFB9
|
NDUFV2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
15.0
|
1.0
|
ACSN
|
12847084
15186778
15526035
15807660
16186509
16200211
16218961
17344420
18199748
18360008
18485875
19131594
19509052
20025615
20816094
|
NDUFB9
|
NDUFS2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
15.0
|
1.0
|
ACSN
|
12847084
15186778
15526035
15807660
16186509
16200211
16218961
17344420
18199748
18360008
18485875
19131594
19509052
20025615
20816094
|
NDUFS2
|
NDUFC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFV2
|
NDUFC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFC1
|
NDUFS3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFC1
|
NDUFV3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFC1
|
NDUFS6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFV2
|
NDUFC1
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFS2
|
NDUFC1
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFC1
|
NDUFS3
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFC1
|
NDUFV3
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFC1
|
NDUFS6
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFS2
|
NDUFS6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFS2
|
NDUFV3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFS2
|
NDUFV2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
13.0
|
1.0
|
ACSN
|
12847084
15186778
15526035
15807660
16186509
16200211
16218961
17344420
18485875
19131594
19509052
20025615
20816094
|
NDUFS2
|
NDUFS3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFS2
|
NDUFV2
|
â—¼ SHARES_COMPLEX
|
|
|
13.0
|
1.0
|
ACSN
|
12847084
15186778
15526035
15807660
16186509
16200211
16218961
17344420
18485875
19131594
19509052
20025615
20816094
|
NDUFS2
|
NDUFV3
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFS2
|
NDUFS6
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFS2
|
NDUFS3
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFV3
|
NDUFS3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFV2
|
NDUFS3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFS3
|
NDUFS6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFV2
|
NDUFS3
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFV3
|
NDUFS3
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFS3
|
NDUFS6
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFV3
|
NDUFS6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFV2
|
NDUFS6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFV3
|
NDUFS6
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFV2
|
NDUFS6
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFV2
|
NDUFV3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFV2
|
NDUFV3
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
PPARGC1A
|
COX5A
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
22.0
|
1.0
|
ACSN
|
12150925
12408816
12533512
12906785
15755954
16469695
17680028
18046414
18048642
18492954
19022819
19568798
19864431
21157483
21981924
23087689
24795729
24973821
25002027
25730849
26159692
28216025
|
PPARG
|
PPARGC1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
16513826
32991581
29182484
|
AKT1
|
PPARGC1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
17554339
|
AKT1
|
RHEB
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
17517883
17277771
18372248
12524439
17386266
|
NFKB1
|
FASLG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
14563113
12655294
15160330
16770006
10671224
|
NFATC1
|
FASLG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
14749367
18547442
11994444
17712479
|
COX5A
|
COX6C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
ACSN
|
11389896
15119951
16051147
17418790
19625251
8194600
|
COX5A
|
COX6C
|
â—¼ SHARES_COMPLEX
|
|
|
6.0
|
1.0
|
ACSN
|
11389896
15119951
16051147
17418790
19625251
8194600
|
COX5A
|
COX6C
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
ACSN
|
11389896
15119951
16051147
17418790
19625251
8194600
|
CHUK
|
RELA
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
9315679
9914500
9721103
10593898
9135156
|
CHUK
|
NFKB1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
9315679
9914500
9721103
10593898
9135156
|
RIPK2
|
CHUK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
10880512
17947236
15620648
11087742
11463746
17965022
10329646
|
AKT1
|
CHUK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
31.0
|
1.0
|
Omnipath
|
15710601
12048203
25241761
19442713
11278366
10485711
15800029
19609947
17570479
17660512
18515365
19088076
10485710
|
CHUK
|
IRS2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
17.0
|
1.0
|
Omnipath
|
16510874
23343194
21285352
22020335
23296977
11274345
16039586
17439715
20920541
20530697
15337521
8545107
19619488
19623618
17565603
17143292
20006983
|
CHUK
|
RELA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
49.0
|
1.0
|
Omnipath
|
17145710
15611276
22110409
19609947
10521409
20863851
20051109
20363318
12767944
26999213
12842894
21903422
19110719
15858576
16382138
22155370
23894194
16046471
15128824
21569639
16846590
8246997
15485852
25341660
15494311
11983155
15980040
15489227
15849198
14636585
23343355
|
CHUK
|
RELB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
17145710
26999213
25267645
14743216
|
CHUK
|
NFKB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
39.0
|
1.0
|
Omnipath
|
12482991
19442713
14743216
15494311
11976329
15489227
16382138
16713569
10022904
10469655
27554194
11158290
11297557
|
NFKB1
|
RELA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
1.0
|
STRING
|
36370105
|
PRKACA
|
RELA
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
17462920
12628924
19197368
19122653
18385332
|
PRKACG
|
RELA
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
17462920
12628924
19197368
19122653
18385332
|
RELA
|
AR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
24466341
16619263
14576180
15517885
14715080
|
RELA
|
AKT1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
20186924
18031796
20649564
|
RELA
|
NFKB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
16778171
20427719
23362108
16513645
1740105
20596645
16513841
19469019
8454856
21420936
16135789
9417120
|
RELA
|
IFNA13
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
7957928
15331713
9446577
8035474
|
RELA
|
HIF1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
18498249
17898080
23185316
|
NFKB1
|
RELA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
88.0
|
1.0
|
Omnipath
|
17145710
16209943
25609649
8428580
12947093
16970925
17072323
2050119
15657065
21270162
11976329
16793322
21544861
22261743
8657102
9824778
11880271
9450761
17962807
21988832
25355951
9722548
18215660
14743216
15799966
10799898
16105840
15218526
8798655
14690596
22139845
22808155
11571291
17072327
16740634
10498867
8255759
8246997
15214841
16846590
15371334
16285893
17072322
17855547
18321863
16493424
7479976
15145317
17561400
20110362
9426183
23687337
12414801
11970949
20154269
20237821
24175631
24634218
34100597
14645533
17982102
21763497
16204234
9437432
20547752
15818410
7628694
|
PRKACA
|
RELA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
11931769
15833743
9150141
17959673
9660950
16135789
12628924
|
PPARG
|
SOD1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
15590897
16951334
19535992
17337254
|
PPARG
|
MMP1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
19046432
19296842
11869069
15090544
|
AKT1
|
SKP2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
23807222
28446188
22733130
19270695
20160512
19549334
21963805
|
HIF1A
|
VHL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
1.0
|
STRING
|
36370105
|
NFKB1
|
HIF1A
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
ACSN
|
17272744
18393939
21725609
23178297
23572150
|
VHL
|
HIF1A
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
19.0
|
1.0
|
ACSN
|
10973499
11900249
12351678
12648680
12820959
15340381
15459660
15652751
15688063
15703371
15721254
16697054
17884153
18931676
18985005
19622404
19686080
19809470
19847258
|
HIF1A
|
COX4I2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
66.0
|
1.0
|
ACSN
|
10102273
10428030
10428780
10435632
10804084
10823814
11557773
11559532
11744734
11756417
11884613
12402042
12676992
12743597
14672622
14684737
14699081
14762718
15024076
15059920
15199147
15240700
15312748
15369676
15379897
15545625
16110315
16126909
16127144
16517405
16517406
16585195
16782875
16888645
17143338
17418790
17533374
17785433
18054315
18056423
18158893
18718909
19211554
20028863
20427344
20535745
20855962
21051947
21765015
22006996
22841746
22850421
22988108
24006507
25043024
25103413
25732824
7493931
7500013
7508926
8089148
8702901
8955077
9486205
9525945
9707622
|
HIF1A
|
VHL
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
12205091
15930297
21887475
22150821
22396654
15962286
23159849
17482131
17140440
16883594
|
HIF1A
|
EPAS1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
20513003
18174278
16924414
19030186
|
HIF1A
|
MET
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
16099863
17028975
|
HIF1A
|
AKT1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
19144925
17220299
17488804
14726529
15277220
|
HIF1A
|
HSP90B1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
19828020
15620698
|
HIF1A
|
AURKA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
18562694
19828020
|
VHL
|
HIF1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
123.0
|
1.0
|
Omnipath
|
17145710
21332579
24857547
12682018
26496610
11292861
11024059
15060148
16278378
12586829
17353276
12004076
12205091
17339318
10823831
11226425
21602890
16862177
15611064
12351678
16140212
11865071
26037477
16611863
10973499
23401859
25361009
11331613
18305400
25438054
14691445
17047048
12538644
22932900
18985005
26735336
21358672
18323857
10878807
19147576
16511565
17973296
23413029
24316222
11986208
12808024
12464182
23318261
22369643
19940151
15721254
20724477
21335603
16391536
23387829
18694926
26743088
14556007
18264140
10353251
15082527
11358837
11292862
11566883
12050673
19123984
17558023
27281823
15805242
11641274
25500545
34174286
24899725
12606543
32535973
17132228
24015760
12086861
11504942
35589690
26215701
22351759
12925778
18222538
17986458
14600153
10944113
23580587
26611735
18426857
20049704
|
AR
|
AKT1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
20589722
11278645
17896924
18687691
22740037
12621049
12063252
22970326
|
PIK3CA
|
AKT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
25793261
19117013
21041639
24950409
21816939
|
AKT1
|
PRKACA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
20016067
23331499
17680028
20214616
17688959
20398329
16537363
17052453
19575820
|
AKT1
|
S1PR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
11583630
17570479
25588843
|
AKT1
|
STK4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
21.0
|
1.0
|
Omnipath
|
22619175
19369195
19737514
19940129
17932490
23431053
11805089
24872389
23893242
17726016
|
AKT1
|
AR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
30.0
|
1.0
|
Omnipath
|
17470458
18349820
29861848
16210317
21601007
17570479
11404460
22155408
12621049
14555644
11156376
|
PRKACA
|
NFKB1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
17462920
12628924
19197368
19122653
18385332
|
NFKB1
|
SOD1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
4.0
|
1.0
|
ACSN
|
15317858
21725609
23178297
23572150
|
NFKB1
|
PRKACG
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
17462920
12628924
19197368
19122653
18385332
|
NFKB1
|
AR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
14576180
15517885
20159994
12165860
16619263
|
NFKB1
|
IFNA13
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
7957928
15331713
8035474
|
PRKACA
|
NFKB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
19531803
12947093
17959673
15642694
15197457
|
PRKACA
|
AURKA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
22.0
|
1.0
|
Omnipath
|
23861900
16222244
16246726
33744274
29764989
26165940
11039908
17545617
27242098
26481147
28869606
26134678
33988677
26831064
33760847
16083426
17895985
|
PRKCA
|
PLCB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
12.0
|
1.0
|
Omnipath
|
9015864
11278470
9349568
2211670
9307019
17570479
21338571
|
PRKCA
|
GRIN2B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
12147342
11306676
8940188
|
PRKCA
|
MET
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
21.0
|
1.0
|
Omnipath
|
17496910
11940581
21386996
15075332
11447289
19615955
8294430
16488589
6321473
8321321
12845332
11313945
17570479
94124523
12040186
19568798
15567848
14585353
|
PRKCA
|
PLD2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
15979581
11042115
11459228
|
PRKCA
|
GRM5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
15894802
9242710
|
PRKCA
|
NFATC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
12351631
9072970
|
PRKCA
|
GRM1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
10823959
15305863
17570479
|
PRKCA
|
ERBB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
16.0
|
1.0
|
Omnipath
|
17496910
11940581
21386996
11447289
19615955
16488589
6321473
8321321
12845332
11313945
18799465
9855018
12040186
19568798
15567848
14585353
|
PRKCA
|
GRIA4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
10366608
12536214
|
IRS2
|
PIK3CA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
9113989
22810696
9374521
|
AR
|
PRKACA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
12933667
10075669
9886819
15691881
|
PRKACA
|
GRIA4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
10366608
12536214
|
PRKACA
|
ATF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
8384217
8663317
20068231
11018520
11335727
11909979
9016641
12414794
|
PRKACA
|
NFATC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
12351631
10611249
9072970
|
PRKACA
|
ERBB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
18799465
9855018
|
HAP1
|
DCTN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
9454836
9361024
|
DCTN2
|
DYNC1LI1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
28.0
|
1.0
|
Reactome
|
17274799
9490716
10679020
10562278
11306556
24891604
16723730
18086915
17283181
18664496
11035033
25453831
18046453
11285137
19564404
8642258
12198549
15728195
10903204
15878873
7691276
8909537
23839779
9150144
10559986
25233431
10036229
24806965
|
PIK3CA
|
GOLGB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
Reactome
|
19345670
9918857
19438505
23168613
27795560
31066629
17764812
11027663
|
AR
|
CCNG2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
20610535
|
AR
|
AKR1C3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
23579488
23995860
22971343
|
POLR2B
|
POLR2E
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
1.0
|
STRING
|
36370105
|
POLR2A
|
POLR2E
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
1.0
|
STRING
|
36370105
|
ATF6B
|
HSPA5
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
17522056
14973138
11256944
|
PEX1
|
PEX10
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
21980954
16854980
15858711
25016021
12717447
|
DCTN4
|
DYNC1LI1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
28.0
|
1.0
|
Reactome
|
17274799
9490716
10679020
10562278
11306556
24891604
16723730
18086915
17283181
18664496
11035033
25453831
18046453
11285137
19564404
8642258
12198549
15728195
10903204
15878873
7691276
8909537
23839779
9150144
10559986
25233431
10036229
24806965
|
POLR2A
|
POLR2K
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
1.0
|
STRING
|
36370105
|
POLR2B
|
POLR2K
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
1.0
|
STRING
|
36370105
|
PHYH
|
PEX10
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
Reactome
|
8858165
24865970
10022913
26138649
9653144
11546814
|