Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
FOXL2 SIRT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19010791
SMAD3 SIRT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22610349 23161884
SUMO1 SP100 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
SMAD3 XRCC6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
XRCC6 RPLP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
FOXL2 CCL3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17360647
SRY NR5A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 30552336 21412441
NR5A1 GNRHR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15561800
CXXC5 SMAD3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
SMAD3 GMEB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
SMAD3 CYP17A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17786540
SMAD3 GNRHR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15561800
FOXL2 PPARGC1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17360647
FOXL2 PTGS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17360647
FOS CYP19A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19022561
FOXL2 FOS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17360647
UBE2I FOS â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16055711 16236267
FOS CGA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15961508
ATF3 CGA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15961508
NR5A2 UBE2I â—¼   SUMOYLATION ✅ 2.0 0.8 intact 17036045 5219211
FOXL2 SF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24451388 20207836
SF1 AMH â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11097782 9774680
NR5A2 CYP17A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17723227 19359379
FOXL2 NR5A2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17360647
FOXL2 IL11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17360647
FOXL2 FST â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19106105 23567549
FOXL2 FSHB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19324968
LHX3 FSHB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15271874
FOXL2 IFNL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17360647
FOXL2 CCL20 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17360647
CREM CYP19A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16946004 14656211
FOXL2 GNRHR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20167115 23372819
FOXL2 CCL3L1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17360647
FOXL2 CYP17A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20207836
FOXL2 CYP19A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16720712
FOXL2 CXCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17360647
FOXL2 AMH â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17728319
FOXL2 CXCL3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17360647
SP100 SUMO1 â—¼   PHYSICAL_INTERACTION 812.0 0.81 STRING 36370105
NR5A1 PPARGC1A â—¼   PHYSICAL_INTERACTION 855.0 0.85 STRING 36370105
FOS SMAD3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 21829441 9732876
SP100 UBE2I â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
SUMO1 SP100 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11313457 16189514 25416956 32296183 16524884 21880768 24654937 15017387 24637324 10212234 17491593 9412458
ATF3 SMAD3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16189514 12718878 20930144
INHBA FST â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 7887917 16198295
FOS CLU â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10406964
FOXL2 SIRT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19010791
NR5A2 SUMO1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 20159957 15923626 19692572
SUMO1 NR5A1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15192092 15192080 21467194
UBE2I NR5A1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15192092 15192080 21467194
NR5A1 NR5A2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23471216 23340581 23537609
NR5A1 CGA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12193378 12920232 14596681
SMAD3 CCND2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16055503 24416423
SMAD3 SOX9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15623506
FOS CYP17A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 19850690 20980388 17895316
UBE2I FOXL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20209145 19744555
LHX3 FSHB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23766128 15271874
CREM FSHB â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21659477 10209256 20008557
LHX3 CGA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19444006 10931853
SRY AMH â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18445271 13678390 10741423
FOXL2 CYP17A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17723227 21664481 20207836
FOXL2 CYP2B6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22847492 16720712 21862621
FST INHBA â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
NR5A2 PPARGC1A â—¼   PHYSICAL_INTERACTION 942.0 0.94 STRING 36370105
UBE2I SUMO1 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 5219915 17491593
CGA FSHB â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
SUMO1 UBE2I â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
FOXL2 BCL2A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19010791 17360647
FOXL2 IER3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19010791 17360647
SIRT1 PPARGC1A â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 15205477 15744310 15989956 18687677 19590512 19960022
SIRT1 PPARGC1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23142079 21633182 19553684
SIRT1 PPARGC1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15744310 20640476 24003218 19553684
SIRT1 XRCC6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17334224 16189514 15205477
FOXL2 SOD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19010791 17360647
FOXL2 SUMO1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 22022399 24390485 19744555 20209145
UBE2I SUMO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 47.0 1.0 Omnipath 21212807 25416956 16713569 18691969 17938407 11735126 25502805 15931224 26496610 16732283 24352468 17353931 18359863 10666456 21174150 8921390 9353268 12924945 21949651 32296183 16524884 17956732 18264111 12764129 10961991 14673145 19684601 17698038 16494873 31515488 23871147 17491593
FOXL2 CH25H â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19010791 17360647
NR5A1 GNRHR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 16613990 17293441 9002645 9607816 11158337
NR5A1 AMH â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 15829514 13678390 21220346 10677509 10446911 16806847 9059565 15383177 12732652 10741423 11518812 12917325 9774680 12907682 11259267 12151099
NR5A1 CYP17A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 22155568 12943735 23358192 9178749 16271033 21467194 23530236 10847589 19007851 11145739 12530662 12765518 11749720 17895316 9029713 16887917 17664281 10098601 15767781 17786540 9851803 20980388 11932209 17053042 9593668 20207836
NR5A1 SRY â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11207191 19457926 12606467
NR5A1 SF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 16595694 7479914 9605933 12907682 16353668 9801462 9013759 10811295 10231566 8625888 9792676 9605934 17786540 9570145 9892016 9121493 12959982 8413309 17331471 17383426 9232190 21081692 20207836
NR5A1 STAR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 33.0 1.0 Omnipath 20924043 22155568 11250933 11427738 19237537 18987158 10319323 18596066 10403575 10852468 23530236 17065415 19455657 9013761 16439455 9801462 9832418 18165439 22427816 23313103 10960482 21632081 17082260 10919277 10499490 20650879 21913902 11111087 19022561 11459805 9029708 15129808
NR5A1 FSHB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 9514159 23536856 12697699 12730328 9570145 23754802
NR5A1 CYP11B2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 21467194 15666827 14645496 8247022 21169726
NR5A1 CYP19A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 34.0 1.0 Omnipath 21273442 10593363 11427738 19237537 17394235 8395654 17804753 19822197 9029737 14736734 23537609 10375033 18165439 16547409 22427816 10731122 20056824 23846226 9973254 20650879 17192407 12213901 19022561 20026603 16621513 12865342 9365194 21586554 24865234 7768959 17331471 21087664
NR5A1 CYP11A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 12101186 11463852 9314578 11427738 10459866 23358192 7479914 23530236 22199361 12530663 21520051 11057754 9013760 9029712 11328860 12145340 15471945 8026494 11325530 11932209 15026180 15289436
NR5A1 MC2R â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 10811295 9178747 15028712 9636648 16857744 17082260 9888512 10770490 15879363 9607816 20650879 15171714 12851310
SMAD3 ACTA2 â—¼   ENZYMATIC_REACTION ✅ 20.0 1.0 ACSN 11013125 11074002 11279127 11376132 11792802 12702545 12809600 15265520 16179589 16713975 18768831 21042762 21098712 21614932 22331441 22652804 23784029 25374926 8515656 9389648
SMAD3 FSHB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 18022758 15375186 24601881 12554780 14764653 14701940 15761025 15707600 21664424 20371653
SMAD3 ACTA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 21990365 15306544 17303001 16858008 12702545 24446247 19261809
FOS PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 15772294 11278336 9620167 17556653 12057991 8906578 17440114
CREM FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 17056544 21757709 17185632 15322221
FOS STAR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 14673133 19022561 18974265 19150388 11911955
FOS FSHB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23178797 18653705 23770611 21659477 23275456 21292826
FOXL2 ATF3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19010791 17360647
FOXL2 TNFAIP3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19010791 17360647
SOX9 AMH â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 9707325 24705165 21187121 12732652 9774680 14689607 11097782 11259267
INHBA FST â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 7678220 8033815 12697670 1592877 16198295
FST INHBA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 16198295 24627466 7887917 22037168
FOXL2 FSHB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20233786 21700720 20810560 22294749
FOXL2 CYP19A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 22847492 20650879 19917504 22019437 16720712 21271216 18805419 17192407 15517586 21862621