Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
SP1 APEX1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18208837 7534297
ESR1 FBLN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15528301 11850827
TP53 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10766163 16713569
ESR1 HSPD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11085516
ESR1 TFF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 6593703
FXR2 PKM â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
SP1 FXR2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16886907
GPR182 MPG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
HSPD1 MPG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
HSPD1 PRNP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8676499 16713569
SP1 LHCGR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12972613
MPG MBD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17129768
XRCC1 MPG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18971944 7294748
TFAP2A MPG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10563836
SP1 MPG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10563836
SRSF1 NPM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218180 16376875
PPP2CA RACGAP1 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 intact 18201571 6166552
PPP2CA SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24382322
TP53 PRNP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24339999 19064990
SP1 PRNP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19064990
TP53 TFAP2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18980971 16636674
UBE2D1 OTUB1 â—¼   PHYSICAL_INTERACTION ✅ 0.81 0.81 mint 8379996 22124327
UBE2D3 UHRF1 â—¼   PHYSICAL_INTERACTION 817.0 0.81 STRING 36370105
OTUB1 UBE2D1 â—¼   PHYSICAL_INTERACTION 817.0 0.81 STRING 36370105
OTUB1 UBE2D3 â—¼   PHYSICAL_INTERACTION 817.0 0.81 STRING 36370105
ESR1 APEX1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31527615 19805454
ESR1 GSTM3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31527615 23576398
UBE2D3 UHRF2 â—¼   PHYSICAL_INTERACTION 834.0 0.83 STRING 36370105
ESR1 TP53 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
ESR1 RRP1B â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 31527615 21182205
ESR1 SET â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 31527615 20348541
ESR1 GNL3 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 31527615 21182205
PSMA1 PSMA2 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
SET APEX1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 12524539 16189514 12628186
TP53 UBE2D1 â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
RPL10 RPL35A â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
UBE2D3 OTUB1 â—¼   PHYSICAL_INTERACTION ✅ 0.87 0.87 mint 8379996 22124327
GNL2 RPL35A â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
NPM1 TP53 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
HSPD1 HSPE1 â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
NUDT21 ZRANB1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
XRCC1 APEX1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 28986522 19934257 11707423 16713569
RRP1B SRSF1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 19710015 20926688 23604122
TP53 APEX1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18208837
TFAP2A ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10497269 19458056 9850080
ESR1 GSN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20034404
MPG ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17129768 14761960
SP1 MIF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21087445 18034423
SP1 NR3C1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12039077 14962081 15249123
TFAP2A NR3C1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9015328 7794935
TP53 NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11080152 16713569
NR3C1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11080152 16713569
SET PPP2CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 9353299 21806989
ESR1 SP1 â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
NCBP1 SART1 â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
SP1 TP53 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
PPP2CA IGBP1 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 8434208 23892082
PSMC2 RAD23A â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
RPL10 RPS29 â—¼   PHYSICAL_INTERACTION 960.0 0.96 STRING 36370105
HSPD1 HSPE1 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
RPL10 RPL35A â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
RPL35A RPS29 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
PSMA2 PSMD7 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
PSMA1 PSMD7 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PSMA1 PSMC2 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PSMA2 PSMC2 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PSMC2 PSMD7 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PSMA1 PSMA2 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
IGBP1 PPP2CA â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
TP53 UHRF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 23677994 19501055 18220474 21382456
APEX1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 18786561 19180539 9119221 19737086 16713569
SP1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 12237165 19351845 11345900 21235772 23209644 12429135 18006846 10982795 22622808 15691879 21191649
ESR1 TFF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 21984905 19858291 11517191 18543253 19935720 17317669 22382029 18414489 17938209 19462000 18322535 22093877 16219765 19933843 16087863 15541729 10037443 22543272 16651411 20422012 23874775
ESR1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 20080630 16115928 22787161 12750288 20696891 17681750 17699779
GNL3 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 20664182 12464630 16713569
HSPE1 HSPD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 18319262 12387818 11050098 10205158 19004824 14717702
IGBP1 PPP2CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 23892082 21988832 20092282 16085932 18782753 24484909 28330616 9647778 21454489 26496610 32296183 24145130 19156129 11371618 10441131
SP1 LHCGR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 10491299 8756564 12972613 16943418
NPM1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 23443559 15144954 16740634 15310764 16376884 12080348
SP1 PPP2CA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19750005 19420015 12076969 21420382
PPP2CA RACGAP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 18201571
PPP2CA TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 17245430 14712210 1848668 16713569 12556559
SP1 SOD2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 7702755 10669635 21419216 23784082 11853549 12388080 18779124 16740634 15869407 22009531 23500038 23834335 12083788 11560779 15706661 11912921
TP53 SOD2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 23784082 20739073 10969820 16740634 22009531 24047462 20061391 15059885 20601193 11313974
TP53 SP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 19846904 15790310 11118296 11384995 21611785 7478550 15967108 18419600 19244234 9865734 18769160
SP1 TFF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18543253 15987735 15541729
UBE2D1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 15169778 15340381 15147722 12820959 10722742 19459846 18006823 10721693 19440234
TP53 FBLN1 â—¼   KO_UP_REGULATES ✅ + 1.03 1.03 PKG 28854368