Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
TP53 CAT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15059885 18487368
CCND1 AR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16461912 0506281103
AR TP53 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19481544 7103716
AR SOD2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20610535 18829485
AR HOXC8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21047772 20610535
AR ESR2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11371645 20610535
AR RARA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12069693 20610535
RXRA AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 15650026
AR RXRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 15650026
NEUROG2 ASCL1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 23139813 16766700
POPDC2 BTG2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18337750 6544442
BTG2 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16849553 15870875
RARA BTG2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17234770
BTG2 CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10669755
BTG2 PER1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 21118894
TP53 BTRC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19196987 0812256106
BTRC SKP1 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
BTRC PER1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15917223 15917222
PIN1 CCNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16713569 9499405
HDAC1 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20049841 20821348
PIN1 CDK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11774038 16713569
CEBPB CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12773552
RXRA CNOT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16778766 5218748
MAPK3 CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15263086 15466214
FOXM1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16809346 17875680
TP53 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10766163 16713569
FOXM1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16809346
ESR1 NFE2L2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 24641954 20623181
RARA ESR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 9841885
ESR2 RARA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 9841885
FBXW11 PER1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15917223 15917222
HIF1A KLK3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17426252 23884959
HRAS PER1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TP53 HRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
TP53 MAPK3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21187340 16050810
RARA NFE2L2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0709483104 18048326
PRKCA SPHK1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12391145 14532121
RARA PRKCA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11525643
SKP2 SKP1 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
CCND1 CDK1 â—¼   PHYSICAL_INTERACTION 805.0 0.8 STRING 36370105
CREB1 TP53 â—¼   PHYSICAL_INTERACTION 805.0 0.8 STRING 36370105
SKP2 CUL1 â—¼   PHYSICAL_INTERACTION ✅ 0.82 0.82 mint 6540196 18239684
SKP1 ESR1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31527615 23770852
FBXL3 CUL1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 10531035 22268729 24085301 29103612
CHAF1A CHAF1B â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
ESR1 TP53 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
CCND1 CUL1 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
AR CCND1 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
ESR1 HDAC4 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 16051668 19893013
ESR1 RXRA â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 9121466 23403292 9717844
CEBPB ESR1 â—¼   PHYSICAL_INTERACTION 849.0 0.84 STRING 36370105
CNOT8 CNOT1 â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 5218748 16778766
TP53 PIN1 â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 12397362 5215850
ESR1 RARA â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 25604459 25303530 9717844
CCND1 ESR1 â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
CDK1 SKP2 â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
PHB2 HDAC1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 24051437 15173318 15140878
HIF1A TP53 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
ESR1 PHB2 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
ESR1 ESR2 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
BTRC FBXW11 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
ESR1 HDAC1 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
MAPK14 TP53 â—¼   PHYSICAL_INTERACTION 879.0 0.87 STRING 36370105
CNOT8 BTG2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 25416956 11136725
AR KLK3 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
ESR1 ANM1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 23403292 31527615 11050077
CUL1 FBXW2 â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
FBXW2 CUL1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 29103612 19398581 14603323 21145461 25515538 22268729 23108047 10531035 28090088
NFE2L2 CAT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22493435
CNOT7 BTG2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 32296183 29395067 11136725 11429045 9712883 25416956
ESR1 BTG2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 19117054
BTG2 HOXB9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10617598
CEBPB CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22242598 11162569 12810706
FOXM1 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23812424 19097132 11572993
CDK1 FOXM1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 18285455 19160488 15024056
CEBPB SOD2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16850160 9372929 24248464
CREB1 PER1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23699513 24065704 12032351
ESR2 ESR1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 19022902 19746436 10706629 12630920 9473491 21182203 29509190 17991765
ESR1 PRMT1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 28539435 18657504 11029009
RXRA ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 9841885 9717844
ESR1 RXRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 9841885 9717844
HIF1A HDAC1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 24015760 16511565 21148070 11641274 17273746
HIF1A SPHK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19828020 18055454
HRAS SPHK1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 12391145 10802064 12776187
TP53 MAPK14 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11437382 15132979 14570892
PRKCA PIN1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 12056906 27558335 19372727
PRKCA RARA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8145770 12000751 10608897
FBXW11 CUL1 â—¼   PHYSICAL_INTERACTION ✅ 0.92 0.92 mint 25609649
FBXW2 SKP1 â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
HIF1A HDAC4 â—¼   PHYSICAL_INTERACTION 0.92 0.92 HIPPIE 30867818 16951198 15280364 21148070 19071119
CNOT6L CNOT8 â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
HDAC1 TP53 â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
FBXL3 SKP1 â—¼   PHYSICAL_INTERACTION 928.0 0.92 STRING 36370105
CUL1 BTRC â—¼   PHYSICAL_INTERACTION ✅ 0.93 0.93 mint 17318178 5219675
SKP1 FBXW11 â—¼   PHYSICAL_INTERACTION ✅ 0.93 0.93 mint 5212166 10644755
SOD1 SOD2 â—¼   PHYSICAL_INTERACTION 944.0 0.94 STRING 36370105
CHAF1A CHAF1B â—¼   PHYSICAL_INTERACTION 948.0 0.94 STRING 36370105
CNOT1 CNOT8 â—¼   PHYSICAL_INTERACTION 948.0 0.94 STRING 36370105
SKP1 CUL1 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 7304783 18818696
RXRA RARA â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 5212283 10698945
ANM1 BTG2 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 11856371 8663146 16713569 16782888
SKP1 BTRC â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 9660940 6547997
CNOT6L CNOT7 â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
FBXW11 SKP1 â—¼   PHYSICAL_INTERACTION 969.0 0.96 STRING 36370105
SKP2 SKP1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 20160477 16880511 19398581 18667692 17463251 34237211 27705803 23911321 22310285 15070733 19270694 27220724 26087183 9827542 22464731 31467278 18818696 24085301 10559916 30254149 29137415 23770852 30728155 10531035 12813041 15469821 20041211 18239684 16189514 28614300 29499133 12609982 9430629 33422522 34080260 16376880 11961546 32350066 23868976 11099048 22524983 10918611 10559858 15342634 23261596 15456869 26474281 22632967 16275325 29997244 15452136
CNOT1 CNOT6L â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
CUL1 FBXW11 â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
RARA RXRA â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
BTRC CUL1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
CNOT1 CNOT7 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
BTRC SKP1 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
CCNB1 CDK1 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
CUL1 SKP1 â—¼   PHYSICAL_INTERACTION 26.0 1.0 ACSN 11516665 11900249 12648680 12820959 14536078 15071497 15147722 15340381 15459660 15489953 15668399 15688063 15703371 16697054 17053147 17884153 18636226 18787170 18931676 19150432 19270156 19622404 19686080 19797085 19809470 19847258
CUL1 SKP2 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 11516665 11900249 12648680 12820959 15071497 15147722 15340381 15459660 15668399 15688063 15703371 16697054 17884153 18931676 19270156 19622404 19686080 19809470 19847258
CUL1 SKP1 â—¼   SHARES_COMPLEX 26.0 1.0 ACSN 11516665 11900249 12648680 12820959 14536078 15071497 15147722 15340381 15459660 15489953 15668399 15688063 15703371 16697054 17053147 17884153 18636226 18787170 18931676 19150432 19270156 19622404 19686080 19797085 19809470 19847258
CUL1 SKP2 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 11516665 11900249 12648680 12820959 15071497 15147722 15340381 15459660 15668399 15688063 15703371 16697054 17884153 18931676 19270156 19622404 19686080 19809470 19847258
SKP1 CUL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 66.0 1.0 Omnipath 9663463 19945379 12684064 19270694 16759355 23951410 10648623 11961546 26540345 26976582 26474281 17290223 9736735 21169563 14685242 16357137 21145461 29070679 15452136 15966899 12628165 21778237 22474075 16189514 22767593 11359933 9430629 10713156 10023660 10228155 12504026 18818696 9827542 12504025 18094045 10066435 23324393 23770852 9990852 12417738 27705803 9636170 21249194 12904573 34499862 11027288 26725323 20832730 19933270 12609982 10230407
ESR1 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8299561 11000528 22391641
NFE2L2 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 24466341 17640564 18588981 15655294 22951256
TP53 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 17202838 18084622 18945670 11504717
AR KLK3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 106.0 1.0 Omnipath 17433535 8626436 11059779 15640443 7686046 11006269 12111703 15368351 24307657 9316650 9719026 11867260 12376473 14767470 16275987 11994312 17075604 20181722 9211894 16342680 12917209 18092350 12648523 17011549 11238180 20069563 10547578 16140973 22245379 12539223 20568894 20103546 18758709 21981678 21541973 12463425 12958311 11894840 19389135 17534890 23662037 15923603 16434977 14517289 22695118 10075669 11377978 16137620 11299734 15131260 21780100 16508948 16425097 22473899 14715080 10625666 18640093 21885566 12670590 14729601 16452400 16081584 10898343 11571582 9044850 15833875 16914734 23884959 15640095 15543614 7514587 12376534 12114445 15557561 18780293 23667504 18829551 12782640 16724108 17426252 11504717 19274665 11034093 17566103 12651911 22179832 21308712 16373397 19013180 22155408 9052414 11532861 17094454 17653089 20709811 22654108 22597536 15514031
AR BTG2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 21172304 20610535 16281084
MAPK14 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 30644418 24424504 21820033 16282370
HDAC1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 11994312 16713569 15640443 12612053 10428808
CDK1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 26573794 12569365 22275373 25704883 17043241 23321516 9725910 24480624 21799006 24424504 28062857 21820033 25950519 28415597 27450452 25691442 21782001
AR KLK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 1712248 19345326 25241761
AR ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 12389206 11032808 16713569 11000528 18988627
TP53 BTG2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 10321740 15741235 19031424 19551855 21394211 16581545
TP53 BTG2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8944033 10669755
BTG2 PRMT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11856371 16782888 8663146 16713569
FOXM1 CCNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11572993 19276163 15671063 11682060 19097132 23812424
TP53 CCNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 12874009 14627709 10051609 11313928 17942917 11892838 15710382 20395210 19470724 12379461 11071927 11522645 15737644 11162602
CDK1 CCNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 38.0 1.0 Omnipath 17145710 23799914 34224728 20117088 16784539 24358021 24508230 19470789 10973963 17283331 20228808 18347064 11242082 12397081 10362260 24582498 15582998 20367638 1833185 12447691 9001210 2570636 24101512 23543736 11331587 12524548 22726437 27626412
FOXM1 CCNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 15817462 15689977 10567581 11572993 11682060 15024056 11391529
TP53 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 24189068 8702807 10669755 22270849 12808109 17942917 19086036 20731879 16061648 20554748 24460719 11798189 10082575 15205322 18769160 19800042
ESR1 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 11477579 12554765 12808053 17166846 22892083 21505052 18414489 9832502 23864650 22396492 22266855 11358796 23891847 22948256 11986316 15282324 15496458 22521644 14764652 15178330 23108396 11410592 15026472 17998543 17681750 18245487 20821348 16860316 11844790 19858209 12929585 15808510 18997820 15217513 16809759 10500157 16980581 17914104
ESR2 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 15313930 14764652 18607069 23891847 11986316 18223478 14729654
CREB1 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 23447091 16503642 18957421 9990041 12504100 10915780 15116100 22271686 14764597 16522741 18713830 24065533 10201372 22751440 18988190 12391146
HIF1A CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23455892 20360945 20179204 15991006
FOXM1 CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 16585184 11572993 10567581 11391529
ESR1 CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8649771 11073968 16061635 9039267
TP53 CDK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 10825186 11593387 12874009 19472317 10514438 11313928 16807237 8270002 17942917 9275177 20395210 11032828 19861536 12889596 19067706
CDK1 RXRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10383391 17570479 12032153
CDK1 FOXM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 23240008 19737929 28387346 19160488 15024056
CDK1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 24173284 12767922 1584757 20661218 26029996 2141171 9467949 17570479 20808790 7862459 11327730 11078726 27726420 8357826 16713569 2156209
ESR1 CEBPB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19652226 18414489
CEBPB TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19135161 23564453 19075931 24333671
MAPK3 CEBPB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 16009338 12213825 8384717 10995751 12048245 15878863 19327116 19443782 15212693 15367685
MAPK14 CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 11175347 12356771 15733869 11160957 11532940 7958915 9829964 12235136 16189514 11335727 9687510 8887554 11698596 23532963 8688081 9528766 11018520 11969286 11377386 11909979
CREB1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16611888 25241761 21295542
HDAC1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 21655924 23242655 18316616 20101232
ESR2 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 14754635 24284820 15207704 18784357 11566442 12630920 22820289 19001520 18511514 14676837 19207817 22622808 21763263 18339713 15087130
ESR1 RARA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 8300756 8912864 8732679 11038749 15831516 15870697 10076999 9626663 18414489
ESR1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 20080630 16115928 22787161 12750288 20696891 17681750 17699779
MAPK14 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 23216744 22431515 12138194 15879307
MAPK3 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 10949034 18372406 15461668 9528769 12118371 14680484 17615152 15059947 16076840 7491495 12093745 15212693 15528270 7838153
PHB2 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 15140878 17932104 26052702 10938099 12943695
ESR1 RARA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23331499 17641689 15831516 9717844 9841885
ESR1 ESR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 12630920 9473491 19746436 21182203 10706629 10022879
FBXW11 SKP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 17145710 25609649 10321728 25900982 15070733 12165731 10230406 21145461 26496610 24500709 10023660 10066435 25332235 19615732 19159283 27705803 10644755 25515538
HIF1A FOXM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22831955 19097132
FOXM1 SKP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16585184 16314512
HDAC1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 30.0 1.0 Omnipath 17145710 10521394 11099047 22266186 20633551 18765668 20075864 17827154 11313951 14976551 25241761 19303885 12426395 19011633 16697957 16959611 16107876 10777477
HIF1A TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 12542982 17390008 9537326 15780936 11696352 10469629 17236590 20706634 15629713 11007955
TP53 HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 9537326 16713569 12124396 15629713 16882692
MAPK3 HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10551817 18519666 24099156
HRAS MAPK3 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15035987 21779496 24957944 22510884 23352452 25907612
TP53 HRAS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21552926 9662334 11127813 21552928
TP53 KLK3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 15540784 11791186 11504717
MAPK14 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 15187187 21675959 18039929 12738796 23397142 11238443 11274345 12697810
MAPK14 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 57.0 1.0 Omnipath 21675959 26247731 20213747 17535811 20506250 15657900 9315650 15642743 19413330 11283254 22975381 10581258 16083285 1088347 21614932 16393692 10884347 21050851 16552184 10747897 15187187 17906639 25789565 15140942 11258706 24818748 19436832 10781582 10212189 17172861 10348343 11078726 11274345
PRKCA MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11704645 12598525 19074803 8903320 9160888
MAPK3 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 10781582 11239457 10958792 28937686 9467949 10348343 24194938 9739174 16713569 12955074 10747897 17237827 25767119 18523266 12393879
MAPK3 SPHK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 16522638 21075214 15623571 14532121 16243846 19914200 18852266 19830907
MAPK3 RXRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 10383391 12048211 10377179 15688020 18003614 27852823 17604322 11606411 20432439 16551633 12824162 15212693 17900311
NFE2L2 SOD2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22493435 18769717
NFE2L2 SOD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 22493435 24417315 22245129
PRKCA NFE2L2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17570479 12947090 12198130
PIN1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 12397362 12388558 17906639 12397361 21741598 16713569 24982848 21900206
PRKCA TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 18812399 9935181 15659650 9315650 19933256 16713569 9571186 1454855
RARA RXRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 50.0 1.0 Omnipath 15528208 19345331 16713569 16769902 21988832 23331499 14521715 15604093 21071413 10828175 10698945 18988627 12393611 25303530 16224062 25241761 1310351 21478865 17641689 7760852 9415406 9121466 7705655 9582446 15171703 10882070 1314167 12052862 31700049
SKP1 SKP2 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 11516665 11900249 12648680 12820959 15071497 15147722 15340381 15459660 15668399 15688063 15703371 16697054 17884153 18931676 19270156 19622404 19686080 19809470 19847258
SKP1 SKP2 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 11516665 11900249 12648680 12820959 15071497 15147722 15340381 15459660 15668399 15688063 15703371 16697054 17884153 18931676 19270156 19622404 19686080 19809470 19847258
TP53 SOD2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 23784082 20739073 10969820 16740634 22009531 24047462 20061391 15059885 20601193 11313974