Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list
Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins
Filter Graph:

0.5
Layout:
  🔂

Click a node or edge for more data...
Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
PSEN1 ACTN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21163940 114280
TP53 ANKRD11 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18840648
DRD4 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PSEN1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21163940 114280
PRKCD APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CSNK2A1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CEBPB PCK2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8093246
CEBPB CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12773552
CREB1 PSEN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11116137
TP53 CSNK2A1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12393879 11239457
DRD4 GAP43 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
EWSR1 EZH2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19502792 19289832
LYPLA2 GAP43 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 14978216 21152083
STAT3 GAP43 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 26865625
NEUROD1 GAP43 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8816493 12562512
PRKCA GAP43 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 2562806 7891109
TCF12 ID2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16549780 0600168103
PRKCA ID2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TP53 ID2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16557594
NEUROD2 NEUROD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8816493 21593321
NEUROD1 NEUROD2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8816493 17924961
TP53 NFATC4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 14990988
CREB1 TP53 â—¼   PHYSICAL_INTERACTION 805.0 0.8 STRING 36370105
POLB TACC2 â—¼   KO_UP_REGULATES ✅ + 0.81 0.81 PKG 28854368
ATM HSPG2 â—¼   KO_UP_REGULATES ✅ + 0.82 0.82 PKG 28854368
NEUROD1 TCF12 â—¼   PHYSICAL_INTERACTION 830.0 0.83 STRING 36370105
ATM CREB1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 15073328 17209043 16293623
CSNK2A1 TP53 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
CALM1 CSNK2A1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
CUL4B EZH2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 27634302 23238014 24292684
APP NCSTN â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
TP53 ATM â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 9843217 9733515 9733514
EZH2 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 20132185 21546904 24006445
ID2 TCF12 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 9242638
PRKCD ITGA6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11389095 12919677
PRKCB PSEN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14576165
STAT3 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 16107692 23874455 20043094
ATM TP53 â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
ID2 TCF12 â—¼   PHYSICAL_INTERACTION 924.0 0.92 STRING 36370105
POLB GAP43 â—¼   KO_UP_REGULATES ✅ + 0.94 0.94 PKG 28854368
ACTN1 ACTN4 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
APP PSEN1 â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
NCSTN PSEN1 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
TP53 MGMT â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 17564708 19846904 19056673 9780001 18555750 8616846 21957016 17234766 12503076 20525765 19531487
ATM CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 16293623 15073328 17525332 15212693 23642045 19115993
ATM TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 452.0 1.0 Omnipath 25301947 21720806 23549171 10713094 16501611 15077171 24886358 17570479 19375142 22028490 16916644 14712210 19303885 9407038 11927276 26700820 28356518 15226429 10723129 19788889 12064478 19705844 26673821 22179422 20931131 19062161 27030982 22891162 17157788 19056039 15758953 12049739 15361830 26620371 25865756 22615843 10196661 10656682 11313957 25088203 15140942 12519769 16319535 24469230 12776195 17234789 27511909 29238697 24608431 12927814 16783362 11875057 16436515 22778557 15181149 12702572 10500142 15178764 28842590 28145533 11591448 17855337 22726545 20206688 26824362 21317290 26104798 24704793 9765199 11314044 16906133 17174997 21593792 17967874 10771484 15585169 19625493 15178448 17596534 16288207 15048074 18353733 24057508 19535302 29344296 23708100 29872395 23705030 25043304 33761896 18431490 21404020 15024084 22559321 12151394 24078877 12080066 33982778 16893723 10958792 18289945 27183917 26337656 29170437 18765533 10744722 21748595 18056442 24820418 15489892 16390936 24086335 28140789 23091651 34523970 32001619 23418564 15279808 21317932 21188172 27559048 16818505 17616578 11551930 19010925 11709713 24711418 28654064 18339864 11173129 17486112 10570149 29774100 18381438 21994612 29558908 15258567 9372954 25860929 16858402 33692124 15775976 34107253 19923893 24958101 10436023 14752509 19962312 19071090 26438152 26093282 20123963 22444248 9843217 17525332 15456784 23533526 11780126 20353948 29290977 11096068 28102346 18855897 20372057 24395704 23890999 15725625 15806145 34103468 18345031 16997395 16293623 28477117 19828454 27630139 12071847 22002314 21315088 27177180 12645530 12890678 26113041 15794754 18560558 22099307 9885574 28903382 15665826 24877058 18332866 10611322 24380814 14871840 19934315 22975381 16489034 18406507 21440540 33687951 10608806 23892398 20730097 16914171 15782130 15177184 22055193 18490454 25867001 24349352 18045533 20663147 17535811 20506250 23982736 22375140 15700044 15279774 19266268 24358288 18697815 14729946 20637859 12242661 12771937 17371838 31940492 19409520 10528155 24037342 17257427 11121242 15310764 23148227 28915641 26928575 21423215 11865061 16949371 27810895 18449195 20711232 27389279 22213803 16713569 10446957 22797063 16478990 29048667 15489221 17241873 21187893 21441950 23907539 20005840 9733514 26244501 21614094 12082529 10467728 10714958 32061892 16636671 29147215 10673501 12091386 25202122 21465263 19544417 25823026 24078903 24038750 22198295 21480565 15177039 28182994 28208785 18674635 20183804 18818083 9925639 17712528 15254178 11483158 27940348 26675349 26261212 19717643 12606585 24559687 14871926 23150668 21329876 28153791 12518062 12767922 23824039 11711532 19251701 28118604 15078887 12393500 17456577 20976220 23380594 12519780 20810927 15533933 22420423 17108107 20145032 18032786 18785202 22037398 23184057 31968249 16729035 12588868 21614932 11546806 18614045 14757188 15029243 14968111 22649771 25512053 34496248 18604166 17609585 17976513 16223874 25433195 18985806 9363941 15159397 34282274 29301278 24505404 26056062 23577291 18272544 18715874 19536869 29334356 10801407 15155458 25201202 24376853 19907922 23525106 14643431 28340339 28051100 19085961 15212693 22201816 20026654 16322229 20080565 9733515 15632067 18672098 22577550 25691451 12637545 12548019 11672523 26984736 12324477 16552184 22084686 10864201 14744854 21532626 17118344 19482562 9561848 12511424 17668048 23358251 18511169 21460853 22022355 12939400 21415014 17292432 25651062 23168260 12111733 16648554 30361254 23678107
CSNK2A1 CALM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 25108821 11827172 8206911 1520270 17173306 17329434 26675311 8639568
STAT3 CEBPB â—¼   ENZYMATIC_REACTION ✅ 33.0 1.0 ACSN 10347215 11875494 12193690 12223527 12907458 14607900 14670306 15218058 15356132 15465827 15573129 16418395 17404308 18776941 19380816 20093776 20237412 20406969 20435894 20580461 20581311 21372296 21765015 21840487 22461508 23124025 23390297 23454751 23953057 24857661 27216177 28186502 7543512
CEBPB TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19135161 23564453 19075931 24333671
CEBPB STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11134330 18266962
CREB1 RPS6KA1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 11160957 11698596 12842905 9770464
RPS6KA1 CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 36.0 1.0 Omnipath 17145710 11175347 12356771 15733869 11160957 11544482 15138267 11532940 9829964 7958915 10558990 12235136 11335727 9687510 8887554 11698596 8688081 9528766 11018520 11969286 11909979
CREB1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16611888 25241761 21295542
CSNK2A1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 53.0 1.0 Omnipath 23443559 15358769 9315650 19413330 11285227 11551930 11883897 22975381 11709713 16083285 1088347 33745968 16552184 10884347 10747897 10673501 7936649 12628923 25241761 21127074 16964247 24725084 10606744 10348343 10951572
PRKCA EWSR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 9341188 17570479 934118 11313922
PRKCB EWSR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19076070 9341188
TP53 LITAF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10321740 21836606 17283168 15197774
NCSTN PSEN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 17145710 12603837 23331499 21071413 14572442 12471034 10993067 18201567 18988627 12032140
PRKCA PSEN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 14576165
PRKCA TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 18812399 9935181 15659650 9315650 19933256 16713569 9571186 1454855
PRKCD TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 17906639 16314418 16377624
PRKCD STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 76.0 1.0 Omnipath 8272872 19413330 11335711 15677447 9343414 15465816 8140422 12576423 11350938 7678052 20068231 12754507 9880505 12763138 9872331 18491316 18669648 8662591 10521505 18691976 27036017 27458446 7537214 8626374 20058876 25280942 16951338 14551213 8164674 12754506 10446219 12361954 12754505 16418226
POLB AHNAK â—¼   KO_UP_REGULATES ✅ + 1.09 1.09 PKG 28854368
ATM GAP43 â—¼   KO_DOWN_REGULATES ✅ - -1.16 1.15 PKG 28854368
POLB PCK2 â—¼   KO_DOWN_REGULATES ✅ - -1.26 1.25 PKG 28854368
ATM AHNAK â—¼   KO_DOWN_REGULATES ✅ - -1.59 1.58 PKG 28854368
ATM ATM â—¼   KO_DOWN_REGULATES ✅ - -2.25 2.25 PKG 28854368
MGMT MGMT â—¼   KO_DOWN_REGULATES ✅ - -4.42 4.41 PKG 28854368
POLB POLB â—¼   KO_DOWN_REGULATES ✅ - -7.24 7.23 PKG 28854368