Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
FLT3 ACAT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 34289383
FLT3 IDH2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 34289383
LRRK2 RHOA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21454543 31046837
SKP2 CDC20 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 20663873 26811472 15014502 28514442 25306918
CDH1 SKP2 â—¼   PHYSICAL_INTERACTION 849.0 0.84 STRING 36370105
DDB2 SKP2 â—¼   KO_DOWN_REGULATES ✅ - -0.86 0.85 PKG 28854368
IDH2 IDH3B â—¼   PHYSICAL_INTERACTION 859.0 0.85 STRING 36370105
IDH2 IDH3G â—¼   PHYSICAL_INTERACTION 859.0 0.85 STRING 36370105
CDC20 SKP2 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
PARK2 SNCA â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
IDH2 IDH3A â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
SPRTN VCP â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
IDH2 SIRT3 â—¼   DEACETYLATION ✅ 3.0 0.9 Reactome 18680753 17923681 16788062
VCP SPRTN â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 22902628 23042605 23042607
NHEJ1 CDC20 â—¼   KO_UP_REGULATES ✅ + 0.9 0.9 PKG 28854368
IDH3B IDH3G â—¼   PHYSICAL_INTERACTION 960.0 0.96 STRING 36370105
NHEJ1 PYGL â—¼   KO_DOWN_REGULATES ✅ - -0.97 0.96 PKG 28854368
IDH3A IDH3G â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
HDAC1 CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 20580679 19182791 21685935 21184735 24424621 18794357
IDH3B IDH3A â—¼   PHYSICAL_INTERACTION 1.0 1.0 HIPPIE 14681455 33961781 31515270 10601238 14555658 26186194 16713569 28514442
LRRK2 SNCA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 20127702 22924508 22658533 24907399 19576176
DDB2 IDH2 â—¼   KO_UP_REGULATES ✅ + 1.01 1.01 PKG 28854368
NHEJ1 IDH2 â—¼   KO_DOWN_REGULATES ✅ - -1.22 1.21 PKG 28854368
DDB2 DDB2 â—¼   KO_DOWN_REGULATES ✅ - -5.71 5.7 PKG 28854368
NHEJ1 NHEJ1 â—¼   KO_DOWN_REGULATES ✅ - -6.47 6.46 PKG 28854368