Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
FLT3 ACAT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 34289383
SP1 ATM â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15837784 11466608
CEBPA MYC â—¼   DOWN_REGULATES ✅ - 2.0 0.8 ACSN 11340171 20581311
SP1 CEBPA â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10373535 12049196
CEBPA SOD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9426001 9013901
HTT DLST â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HSPD1 FGFR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PDX1 FGFR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11130726 21779870
FLT3 IDH2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 34289383
NR3C1 GH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22160539 3018491
HSPA9 GRPEL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
MYC HSPA9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11983916
HSPD1 MPG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
MYC HSPD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10737792
VCP HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TNIK MAP3K7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1001376 22904686
SP1 MPG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10563836
PDX1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11687580 17317781
MYC VCAM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11318876 10528192
OTUB1 SOD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SP1 PDHA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8476854
PDHA1 PDP1 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 intact 8226367 7782287
SP1 VCAM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11133225 7499419
FGFR1 CDC37 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 18022941 31980649
MYC SP1 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
PDHB PDK1 â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
HSPA9 HSPD1 â—¼   PHYSICAL_INTERACTION 862.0 0.86 STRING 36370105
PDHA1 PDK1 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
HTT VCP â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
MYC NIT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
FGFR1 ACAT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 27867011
ATM METTL3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 32615088 17525332
NR3C1 CEBPA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 27777311 11279134
CEBPA GH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11914124 11579200 8702932
MYC CEBPA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12873812
CEBPA MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12873812
SP1 HTT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22399227 20018729
MYC PDHA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11274368 16713569
SP1 NR3C1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12039077 14962081 15249123
PDK1 PDHA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 16436377
PDHA1 PDHB â—¼   CORRELATES + 0.91 0.91 CCLE 31978347
ATM ACAT1 â—¼   KO_UP_REGULATES ✅ + 0.92 0.92 PKG 28854368
GRPEL1 HSPA9 â—¼   PHYSICAL_INTERACTION 950.0 0.95 STRING 36370105
PDHA1 PDHB â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
ATM SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 23148884 18619531 22826432 27156884 29144413 29294106 23046908 17609267 18171990
MYC CEBPA â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 15681429 17082780 7556187 8076602 20097210 12695333 15867211 19259613
FGFR1 PDK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22195962
SP1 GH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 1427648 8754847 2181288 2659342 10698168 2033067
MYC HSPD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 19022255 12695333 14519204 21995449 11983916 11085504
MYC PDK1 â—¼   ENZYMATIC_REACTION ✅ 20.0 1.0 ACSN 11274345 11283613 11283614 11704864 16517405 16517406 17055429 17558397 17785433 17873522 20027199 20237412 20551172 20581311 20713526 21406394 2191300 22067385 25002027 28536364
SP1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11470523 9492315 2284094 8437848 7753559 8355712 2057364
MYC PAICS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12695333
PDHA1 PDK1 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 7499431 11485553 9405293 8798399 11486000
PDK1 PDHA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 45.0 1.0 Omnipath 17081983 20166139 18767875 17474719 7782287 19415658 15302935 11485553 20068231 19341700 22195962 82003483 18691976 18088087 16436377 7273851 12676647 20058876 11486000 18212344
PDP1 PDHA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 14644048 20208177 7782287 16545080 16436377
PDHA2 PDK1 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 7499431 11485553 9405293 8798399 11486000
PDHB PDK1 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 7499431 11485553 9405293 8798399 11486000
PDK1 PRKCZ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11222751 18691976 10075713 9768361 9748166
PRKCZ SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 23148884 16943418 18258854 19464346 27320013 17049555 20953893
SP1 SOD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 8921911 18586551 18608091 21056687 24946209 11724400 9867871
ATM ATM â—¼   KO_DOWN_REGULATES ✅ - -2.25 2.25 PKG 28854368