Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
SOX2 CDKN1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22469032 22855803
DOT1L CTNNB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1000539 21103407
EP300 H2AX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20488183
OTUB1 SOD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ATP5PO RAD52 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
DLD BCKDHA â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 2188967 10745006
LRRK2 AHCYL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
RYBP BMI1 â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 24981860
TUBA1A HDAC6 â—¼   DEACETYLATION ✅ 2.0 0.8 intact 5215415 12024216
PRKN CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20418918
CTNNB1 SOX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 24291232 24482235
RYBP SOD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HADHA SIRT5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
AK2 ADCY5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PRKN HEXD â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
CALM2 ITPKA â—¼   PHYSICAL_INTERACTION 804.0 0.8 STRING 36370105
EP300 ATF2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 10327051 24069158
HDAC6 EP300 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19344692 15102857 12718889 22778253 23133622
LRRK2 LDHA â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31046837 24725412
LRRK2 CKAP5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31046837 24725412
VCAM1 LDHA â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
LDHA LDHC â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
VCAM1 LDHB â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
LDHB LDHC â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
HDAC6 CFTR â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 31501480 22069321 14675537
PEX5 ACOT8 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 25416956 20178365 22002062 30378028
LRRK2 TUBA1A â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
GNMT HPRT1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HuRI 32296183
CFTR LDHA â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 26618866 31324722 29924966
CDKN1B CKS1B â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
AKR1C1 AKR1C3 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
AKR1C3 AKR1C4 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
POT1 TERF1 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
ATP6V0A1 ATP6V0D1 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
CDKN1B COPS5 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
HDAC6 TUBA1A â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
SPRTN VCP â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
DNM1L LRRK2 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
BMI1 RYBP â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 34316702 20601937 27705803 22325352 33961781 24981860 26186194 24457600
LDHB LDHA â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 32296183 25416956 21988832 25910212 22863883 33961781 21516116 22939629
LDHA LDHB â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
CFTR VCP â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
COPS5 CUL4B â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
BMI1 RYBP â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
EP300 HDAC6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15102857 19344692
H2AX OTUB1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
VCP SPRTN â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 22902628 23042605 23042607
LRRK2 DNM1L â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 22228096 22639965 24282027 29541021 23813973
FHIT CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18077326
COPS5 CUL3 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
CTNNB1 EP300 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
RAC3 SOD1 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
CYP51A1 HSD17B7 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
TUBA1A TUBB3 â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
AHCYL1 AHCYL2 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
ATF2 FN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 21479385 8335091 10471826 8703044 9151819
MAPK13 ATF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 15187187 19436832 9207191 10581204 15140942 20506250 21614932 19135240 16393692 12244047 11274345
CKS1B CDKN1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 15340381 15147722 12813041 12820959 18805092 16209941 12140288 11516665 15071497 15688063 19584057
COPS5 CDKN1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 17145710 22350412 15688030 18926707 24671224 12082530 18202760
CUL4B COPS5 â—¼   DEMETHYLATION ✅ 9.0 1.0 Reactome 19748355 18926707 16401342 18093314 23535663 23583660 22959436 16943200 23535662
EP300 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 11050151 18987336 15806138 15060161 17410209
MEN1 CTNNB1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 19737400 9694656 10473551 19079338
VCP CUL3 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 33444648 11733065 28115426 15652483 10811609 29153394
FGFR1 LDHA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 28516914 34452627 21969607 28218905 33572095
FGFR1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 17496910 25241761 22558232 11401320 12040186 19568798 14585353
PTPRF CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10187801 9245795 11245482 12095414
AGPS PEX5 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 26220973 9668159 25538232 26138649 11546814