CCNA1
|
CDKN1B
|
â—¼ PROXIMITY
|
|
|
2.0
|
0.8
|
intact
|
29997244
20178071
|
BLZF1
|
CKS2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
8153045
21516116
|
BUB1B
|
CDK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
11285280
10679238
|
CCNA2
|
CDT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17145710
14993212
|
TP73
|
CCNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
15737644
|
E2F4
|
CCNB2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
12771133
17531812
|
E2F4
|
CCNB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15574595
18319725
|
TP53
|
CDC20
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
19273532
17873905
|
E2F4
|
CDC20
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15574595
18319725
|
TP53
|
CDC20
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
19273532
|
PBK
|
CDK1
|
â—¼ PHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
10779557
5212518
|
HINFP
|
CDK2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
14585971
19590016
|
CKS1B
|
CDK2
|
â—¼ PROXIMITY
|
|
|
2.0
|
0.8
|
intact
|
29997244
20178071
|
KMT2A
|
CDKN1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16997566
|
MYC
|
CDKN1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
24704206
26701207
|
GMNN
|
CDT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15232106
5217098
|
CDT1
|
GMNN
|
â—¼ PROXIMITY
|
|
|
2.0
|
0.8
|
intact
|
17318181
5219681
|
CKS2
|
CENPE
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12714746
|
TSC22D4
|
CKS2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
EEF1A1
|
CKS2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
UNC119
|
CKS2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
E2F4
|
CKS2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17531812
|
MYC
|
CKS2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11085504
|
HINFP
|
CKS2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17974976
|
TP53
|
E2F4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
15574328
24096481
|
E2F4
|
GMNN
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
14990995
|
E2F4
|
RAD51AP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18319725
12909625
|
E2F4
|
PBK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15782160
18319725
|
E2F4
|
GMNN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18319725
14990995
|
GRB2
|
EEF1A1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5216105
12577067
|
TP53
|
EEF1A1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18431400
|
GRB2
|
SSBP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5216105
12577067
|
HINFP
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
8153045
21516116
|
MYC
|
LDHB
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11983916
|
SSBP1
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19066201
|
TP73
|
TP63
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
19815500
0905867106
|
CDK1
|
CCNA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.81
|
0.81
|
HIPPIE
|
14681455
8565853
16009130
1628647
7799941
|
FZR
|
GEMI
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.81
|
0.81
|
HIPPIE
|
11562349
29875408
21700221
|
UBE2S
|
FZR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.81
|
0.81
|
HIPPIE
|
25306923
32905768
19822757
23708001
25306918
|
FZR
|
UBE2C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.81
|
0.81
|
HIPPIE
|
21700221
23707760
25306923
23670162
32905768
19822757
18485873
|
FZR
|
BUB1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.81
|
0.81
|
HIPPIE
|
23091007
25505175
33306668
|
FZR
|
CDC20
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.81
|
0.81
|
HIPPIE
|
23643811
16287863
17403670
23091007
33306668
|
UBE2C
|
CDC20
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.81
|
0.81
|
HIPPIE
|
17443186
29735662
34382737
32152539
19820702
|
CKS2
|
CDN1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
CKS1
|
GEMI
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
CDK1
|
GEMI
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
26186194
|
CKS2
|
GEMI
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
GEMI
|
E2F4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
IKZF5
|
CKS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
CKS1
|
CDT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
CKS1
|
CCNE1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
GA2L1
|
CKS2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
ZADH2
|
CCNB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
IKZF5
|
CCNB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
CKS2
|
CCNE1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
CDC37
|
CDK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
25036637
17525741
|
CDK2
|
CDK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
21319273
|
MYC
|
CDK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
17314511
29467282
|
CDK2
|
E2F4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
25852190
33961781
|
CKS2
|
CDT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
IKZF5
|
CKS2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
CENPE
|
BUB1B
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
+
|
0.82
|
0.82
|
Signor
|
12925705
|
CDC20
|
CDK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
826.0
|
0.82
|
STRING
|
36370105
|
CDT1
|
CCNA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
15138268
15004027
31160578
14993212
|
CCNA2
|
CCNA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
33961781
28514442
26186194
|
FZR
|
CKS2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
33961781
28514442
33306668
|
CCNA2
|
GEMI
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
33961781
28514442
26186194
26496610
|
CDK3
|
GEMI
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
33961781
28514442
26186194
|
CDC20
|
CKS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
15014502
28514442
33961781
|
KCC1D
|
CKS2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
33961781
28514442
26186194
|
GA2L1
|
CCNB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
33961781
28514442
26186194
|
CDK1
|
CDK3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
33961781
28514442
26186194
|
CDK3
|
CDT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
33961781
28514442
26186194
|
CCNA1
|
CDT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
835.0
|
0.83
|
STRING
|
36370105
|
CDK1
|
CDC25C
|
â—¼ PHOSPHORYLATION
|
✅
|
+
|
0.83
|
0.83
|
Signor
|
8119945
|
CDC25C
|
CDK1
|
â—¼ DEPHOSPHORYLATION
|
✅
|
+
|
0.83
|
0.83
|
Signor
|
19574738
|
CDK1
|
FZR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
33961781
28514442
20581839
33306668
|
MYC
|
FZR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
21150319
28205554
28628118
|
TACC3
|
FZR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
19823035
25375378
|
CKS2
|
CKS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
33961781
28514442
2227411
|
CDK1
|
CDC20
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
28514442
26912231
10799291
|
CCNB1
|
PKMYT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
841.0
|
0.84
|
STRING
|
36370105
|
BUB1B
|
FZR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
842.0
|
0.84
|
STRING
|
36370105
|
FZR1
|
UBE2S
|
â—¼ PHYSICAL_INTERACTION
|
|
|
842.0
|
0.84
|
STRING
|
36370105
|
CKS2
|
TEN1-CDK3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
843.0
|
0.84
|
STRING
|
36370105
|
CDK2
|
TEN1-CDK3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
849.0
|
0.84
|
STRING
|
36370105
|
CCNA2
|
PMYT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
33961781
26496610
26186194
28514442
32707033
|
CKS1
|
PMYT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
33961781
28514442
32707033
|
CKS2
|
PMYT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
33961781
28514442
32707033
|
CCNB2
|
PMYT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
33961781
32707033
26496610
|
CDKN1B
|
CCNE1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.85
|
0.85
|
mint
|
34591612
|
CDKN1B
|
CDK1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.85
|
0.85
|
mint
|
34591612
|
CCNA1
|
FZR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
858.0
|
0.85
|
STRING
|
36370105
|
CDC20
|
FZR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
858.0
|
0.85
|
STRING
|
36370105
|
CCNB2
|
CKS2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
859.0
|
0.85
|
STRING
|
36370105
|
CDK2
|
FZR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
28514442
33961781
23670162
12560341
11340163
26083744
23972993
33306668
|
CCNA2
|
FZR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
33961781
27653696
21700221
31455778
31489637
19483727
26186194
28514442
18485873
33306668
|
CCNB2
|
CKS1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
860.0
|
0.86
|
STRING
|
36370105
|
CDK2
|
TP53
|
â—¼ PHOSPHORYLATION
|
✅
|
+
|
0.86
|
0.86
|
Signor
|
24173284
|
CCNA1
|
CDK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
868.0
|
0.86
|
STRING
|
36370105
|
ZWINT
|
SPC24
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
33961781
20360068
15824131
24981860
26496610
26186194
28514442
|
CDN1B
|
CCNB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
33961781
8756624
31822694
26496610
|
CDK2
|
GEMI
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
23455922
26186194
33961781
|
CCNA2
|
CDT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
CDC20
|
CCNB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
23239745
20383333
25161877
31230944
20080579
25306923
10799291
20733055
25482201
23091007
32152539
19820702
25825779
22014574
12956947
24151075
23007861
17360335
22193957
19826003
26912231
14701726
23791783
27522463
25246557
31455778
18471975
23288039
23979597
11562349
26387737
33082289
11804586
25505175
|
CDK2
|
CDC20
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
33961781
23455922
26811472
25852190
28514442
|
CDKN1B
|
CKS1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
BUB1B
|
ZWINT
|
â—¼ PHYSICAL_INTERACTION
|
|
|
874.0
|
0.87
|
STRING
|
36370105
|
CDN1B
|
CDK3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
33961781
9811456
26186194
28514442
23602568
|
FZR
|
CCNB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
33961781
20383333
16921029
25161877
20080579
11598127
32393902
29973362
21700221
23670162
25306923
24163370
18722180
25490258
27259151
27114510
31350353
25825779
22014574
33306668
12956947
23708605
19475398
16365295
28514442
14701726
21241890
22529100
25241761
11562349
32165494
|
CDT1
|
FZR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
18162579
33306668
|
CKS1
|
CCNA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
33961781
33422522
18471975
26496610
11907280
16209941
19483727
26186194
28514442
|
CCNB1
|
CDK3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
27030811
28514442
|
CDC20
|
UBE2S
|
â—¼ PHYSICAL_INTERACTION
|
|
|
880.0
|
0.88
|
STRING
|
36370105
|
CDT1
|
CDK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
28514442
26186194
14993212
31160578
|
SPC24
|
ZWINT
|
â—¼ PHYSICAL_INTERACTION
|
|
|
881.0
|
0.88
|
STRING
|
36370105
|
TP53
|
TP63
|
â—¼ PHYSICAL_INTERACTION
|
|
|
882.0
|
0.88
|
STRING
|
36370105
|
BUB1B
|
CENPE
|
â—¼ PHYSICAL_INTERACTION
|
|
|
885.0
|
0.88
|
STRING
|
36370105
|
CDK1
|
CDT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
888.0
|
0.88
|
STRING
|
36370105
|
CDK1
|
CDN1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
33961781
31822694
26186194
24358021
18615582
28514442
23602568
32707033
23543736
|
CCNE1
|
CDN1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
33961781
8978686
20837141
9218599
9891079
31822694
9716181
23910095
9192873
9632134
11940657
14691455
8756624
9660939
17254967
24632684
19470470
17293600
8891332
10393546
17254966
9311993
25241761
12529437
27175940
|
PMYT1
|
CCNB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
33961781
23397142
10373560
26496610
32707033
|
CKS1
|
CCNB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
33961781
30674583
18471975
26496610
28514442
19786724
|
CDK3
|
SPDYE4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HuRI
|
32296183
|
CDC20
|
CCNA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
33961781
26496610
23007648
26960431
19098431
25669885
20733051
25750436
32152539
25306918
19483727
28514442
19826003
10679238
27522463
26811472
31455778
32307883
18471975
26186194
|
CDK1
|
CCNA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
14681455
33961781
33422522
17679094
25852190
26496610
24302728
19483727
12853968
26186194
21308745
8463339
28514442
9053846
23602568
32707033
|
CDT1
|
CCNA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
33961781
14993212
26496610
18184650
31160578
26186194
28514442
|
CKS2
|
CDK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
33961781
26344197
25852190
18471975
26496610
26186194
32707033
28514442
23602568
19786724
|
CDK3
|
CKS2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HuRI
|
32296183
|
EXO1
|
UBE2C
|
â—¼ KO_UP_REGULATES
|
✅
|
+
|
0.89
|
0.89
|
PKG
|
28854368
|
CDK1
|
CDKN1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
893.0
|
0.89
|
STRING
|
36370105
|
CDK2
|
CDT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
894.0
|
0.89
|
STRING
|
36370105
|
CDT1
|
TEN1-CDK3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
895.0
|
0.89
|
STRING
|
36370105
|
CCNB1
|
CKS1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
895.0
|
0.89
|
STRING
|
36370105
|
CDKN1B
|
TEN1-CDK3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
897.0
|
0.89
|
STRING
|
36370105
|
CCNA1
|
CDKN1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
898.0
|
0.89
|
STRING
|
36370105
|
CCNA2
|
CKS1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
898.0
|
0.89
|
STRING
|
36370105
|
CCNA1
|
CDN1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
16774918
15583032
33961781
18692475
32814053
10022926
26264872
16189514
7478582
29997244
|
TP53
|
CCNA1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
17530187
15456866
|
CKS1
|
CDN1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
18805092
23910095
33961781
12140288
16209941
12813041
19584057
28514442
|
CDN1B
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
11278754
16189514
19523899
|
CDN1B
|
CCNA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
33961781
18177895
26496610
27720894
31822694
9716181
12947099
8684460
20596027
16209941
28514442
9660939
12501191
15890360
33422522
24632684
17254966
9311993
26186194
9724724
|
PMYT1
|
CDK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
33961781
9268380
25852190
10373560
26186194
28514442
23602568
32707033
|
CKS1
|
CDK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
33961781
26344197
25852190
18471975
22939629
9774639
26496610
26186194
32707033
25416956
23602568
19786724
|
CDC20
|
BUB1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
33961781
25502805
11702782
21407176
23643811
23239745
29973720
23007648
22566641
27939943
12196507
18591651
19098431
24464857
25383541
26960431
23443559
25669885
22000412
26986935
29432156
20512932
20733051
21926987
25012665
25833949
27694884
11907259
18997788
25482201
25750436
24581499
23091007
27114510
19820702
25306918
21300909
32707033
32152539
11535616
20360068
22100920
33310066
17598981
25852190
25673878
28404789
24151075
23345399
17360335
22193957
28514442
21335556
26912231
23791783
26811472
25246557
11274370
21937719
11030144
19407811
25241761
28096334
20212161
25505175
30341343
|
E2F4
|
CCNA2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
15510213
10766737
18319725
|
E2F4
|
CCNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
15510213
|
E2F4
|
CDC25C
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
11799066
|
MYC
|
CDC25C
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12747840
22446629
|
TP63
|
CDC25C
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
19861536
|
PKMYT1
|
CDK1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
ACSN
|
10373560
10504341
12738781
|
CDT1
|
CDK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
23455922
14993212
26496610
15855168
31160578
15004027
|
CDKN1B
|
E2F4
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
11884610
7797074
9144196
|
KMT2A
|
CDKN1B
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16169901
19318494
19031738
|
E2F4
|
UBE2C
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
17671431
|
E2F4
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
11564866
12150994
18319725
|
TP53
|
EEF1A1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
23799104
9269753
18431400
|
HSP90AA1
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
900.0
|
0.9
|
STRING
|
36370105
|
MYC
|
HSP90AA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
28914785
12644583
|
MYC
|
UBE2C
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12747840
22170434
|
TP73
|
TP63
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16413471
21436470
18026135
|
TP73
|
TP63
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
11238924
19815500
10373484
|
CDK3
|
CKS1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HuRI
|
32296183
|
CCNA2
|
CKS2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
903.0
|
0.9
|
STRING
|
36370105
|
CKS1B
|
TEN1-CDK3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
917.0
|
0.91
|
STRING
|
36370105
|
CCNB2
|
CDK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
918.0
|
0.91
|
STRING
|
36370105
|
CDC20
|
CDK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
918.0
|
0.91
|
STRING
|
36370105
|
CDK2
|
FZR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
918.0
|
0.91
|
STRING
|
36370105
|
CDK2
|
CKS2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
919.0
|
0.91
|
STRING
|
36370105
|
CKS1
|
CCNB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.92
|
0.92
|
HIPPIE
|
33961781
28514442
19786724
|
CKS2
|
CCNB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.92
|
0.92
|
HIPPIE
|
33961781
30674583
18471975
26496610
28514442
19786724
|
CKS2
|
CCNB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.92
|
0.92
|
HIPPIE
|
33961781
28514442
19786724
|
CCNE1
|
CDK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
920.0
|
0.92
|
STRING
|
36370105
|
CCNA2
|
CDK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
929.0
|
0.92
|
STRING
|
36370105
|
CDC20
|
CCNA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.93
|
0.93
|
HIPPIE
|
19477924
10679238
|
CCNA1
|
CDK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
933.0
|
0.93
|
STRING
|
36370105
|
CKS1B
|
SPDYE4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.93
|
0.93
|
HuRI
|
32296183
|
CDC20
|
UBE2C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
937.0
|
0.93
|
STRING
|
36370105
|
CDK1
|
PKMYT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
937.0
|
0.93
|
STRING
|
36370105
|
FZR1
|
UBE2C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
937.0
|
0.93
|
STRING
|
36370105
|
CKS1B
|
CDK2
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.94
|
0.94
|
mint
|
8601310
5220942
|
CDK2
|
CDK3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.94
|
0.94
|
HIPPIE
|
28514442
23455922
26186194
33961781
|
CDK2
|
CDKN1B
|
â—¼ PHOSPHORYLATION
|
✅
|
-
|
0.95
|
0.95
|
Signor
|
17409098
|
CCNE1
|
CDKN1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
959.0
|
0.95
|
STRING
|
36370105
|
CDKN1B
|
CCNA2
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.96
|
0.96
|
mint
|
34591612
|
CDK2
|
CCNE1
|
â—¼ PHOSPHORYLATION
|
✅
|
-
|
0.96
|
0.96
|
Signor
|
19561641
|
CDK2
|
CDN1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
33961781
8978686
23455922
17671428
16782892
26496610
17053782
9218599
12417722
33854239
23602568
21423803
31822694
17698606
12972555
10585280
11521189
9472014
9380407
8684460
15355997
25852190
9192873
9632134
11940657
15619620
18850315
16326706
19631451
10198259
16189514
9660939
26450989
28514442
15890360
17254967
17418410
9658399
10323868
24632684
33422522
18285702
10393546
17254966
9311993
25241761
12800980
19139918
27998760
26186194
24358021
12529437
27175940
18615582
9724724
21439954
15557281
15647383
|
CDT1
|
GEMI
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
33961781
15257290
20980834
18617514
26496610
18184650
31160578
19906994
15138268
16482215
15855168
27107012
17261582
15232106
28514442
30018425
14993212
11125146
17318181
21543332
14578910
18162579
22581055
|
CCNB1
|
FZR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
970.0
|
0.97
|
STRING
|
36370105
|
CCNB1
|
CDC20
|
â—¼ PHYSICAL_INTERACTION
|
|
|
970.0
|
0.97
|
STRING
|
36370105
|
CKS2
|
CDK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
33961781
23455922
25852190
26496610
26186194
28514442
19786724
|
CDKN1B
|
CDK2
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.97
|
0.97
|
mint
|
34591612
|
GMNN
|
CDT1
|
â—¼ PROXIMITY
|
✅
|
|
0.97
|
0.97
|
mint
|
17318181
5219681
|
CCNB2
|
CDK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
971.0
|
0.97
|
STRING
|
36370105
|
CCNE1
|
TEN1-CDK3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
972.0
|
0.97
|
STRING
|
36370105
|
CCNA2
|
TEN1-CDK3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
973.0
|
0.97
|
STRING
|
36370105
|
EXO1
|
CKS2
|
â—¼ KO_UP_REGULATES
|
✅
|
+
|
0.97
|
0.97
|
PKG
|
28854368
|
CDK2
|
CCNA2
|
â—¼ PHOSPHORYLATION
|
✅
|
+
|
0.97
|
0.97
|
Signor
|
10652300
|
CCNA2
|
CDC20
|
â—¼ PHYSICAL_INTERACTION
|
|
|
979.0
|
0.97
|
STRING
|
36370105
|
CDK3
|
CKS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.98
|
0.98
|
HIPPIE
|
33961781
32296183
26186194
28514442
7809159
23602568
|
CCNB1
|
CDK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
982.0
|
0.98
|
STRING
|
36370105
|
CCNA2
|
CDKN1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
985.0
|
0.98
|
STRING
|
36370105
|
CCNB1
|
CKS2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
988.0
|
0.98
|
STRING
|
36370105
|
CDK2
|
CKS1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
988.0
|
0.98
|
STRING
|
36370105
|
CDK2
|
CKS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.99
|
0.99
|
HIPPIE
|
8601310
23455922
33961781
12140288
26496610
7809159
23602568
19786724
26344197
31467278
25852190
16979657
28514442
16189514
15772084
9840943
26186194
17409098
29997244
|
CDK2
|
CCNE1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.99
|
0.99
|
HIPPIE
|
33961781
8978686
23455922
15980415
24771265
15670215
15514162
26496610
20837141
25728284
9891079
33854239
10330164
8867812
23602568
14681455
11433299
16431923
9716181
20587660
28137908
14701826
14536078
17361108
33854235
10827081
8662825
9472014
25852190
16223725
9192873
11940657
12839982
11132966
10359664
7799941
21092281
8647086
8756624
19631451
28514442
21372285
9660939
17431037
17254967
29439025
19470470
21241890
9840943
17970072
1388288
18559665
12800980
15004009
26186194
24358021
23853094
12529437
15557281
|
CDK1
|
CKS2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
CDC37
|
HSP90AA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
CDK1
|
CKS1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
CDT1
|
GMNN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
CDK2
|
CDKN1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
BUB1B
|
CDC20
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
0.99
|
STRING
|
36370105
|
CCNA2
|
CDK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
0.99
|
STRING
|
36370105
|
CCNB1
|
CDK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
0.99
|
STRING
|
36370105
|
CCNE1
|
CDK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
0.99
|
STRING
|
36370105
|
CDKN1B
|
CCNA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
15583032
29997244
7478582
10022926
18692475
32814053
16189514
|
CENPE
|
BUB1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
12925705
10477750
20237434
9763420
|
CDK1
|
BUB1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
20016069
23637705
29971233
23345399
23079597
26259146
17785528
20633640
19015317
33207204
|
BUB1B
|
CDC20
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
63.0
|
1.0
|
Omnipath
|
11535616
23443559
11030144
25383541
19098431
23239745
18997788
22000412
15525512
25750436
12196507
16647857
23791783
25482201
25505175
25502805
22100920
25246557
20512932
11907259
25852190
21937719
11702782
20733051
25669885
25306918
19820702
22566641
26811472
25241761
25833949
25012665
27114510
24464857
21407176
17598981
23643811
19407811
23091007
17360335
11274370
18591651
24581499
20360068
26986935
31515488
25673878
21926987
24151075
|
E2F4
|
CCNA2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
17531812
17121828
21311680
15448153
|
TP53
|
CCNA2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
16931621
8270002
9275177
19671680
16571800
8641461
9360984
21952947
|
MYC
|
CCNA2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
8386381
10713672
12835716
7608142
12937171
14519204
14729654
|
CDC20
|
CCNA2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
15577895
10679238
18471975
15840442
25669885
|
CDK2
|
CCNA2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
81.0
|
1.0
|
Omnipath
|
8756328
7553852
11377199
17145710
23602568
11983168
12044161
19483727
12853968
16209941
8397207
15455144
19631451
8475101
24358021
15557281
8684460
12941338
15647383
15890360
21447625
9380407
26496610
11141566
25852190
15189033
14656438
20733051
21241890
10652300
25669885
12244298
26186194
10930425
9660939
10477583
24302728
15239650
19773423
8463339
16290148
10924145
11907280
17361108
17254966
8662825
15828833
18471975
9724724
7630397
10559988
9716181
11940657
23455922
|
CDKN1B
|
CCNA2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
16.0
|
1.0
|
Omnipath
|
17145710
8684460
26186194
9660939
17254966
15890360
16209941
12947099
12501191
26496610
9724724
9311993
9716181
|
CCNA2
|
CDK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
17145710
1833185
10924145
8423786
|
CCNA2
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
14640983
10884347
16713569
|
E2F4
|
CCNB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
17531812
15855772
22508987
|
TP53
|
CCNB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
15.0
|
1.0
|
Omnipath
|
12874009
14627709
10051609
11313928
17942917
11892838
15710382
20395210
19470724
12379461
11071927
11522645
15737644
11162602
|
MYC
|
CCNB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
12747840
11522645
11983916
19470724
|
PKMYT1
|
CCNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
17145710
9001210
12814430
10373560
18319725
12738781
26496610
23397142
10504341
|
CDK1
|
CCNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
38.0
|
1.0
|
Omnipath
|
17145710
23799914
34224728
20117088
16784539
24358021
24508230
19470789
10973963
17283331
20228808
18347064
11242082
12397081
10362260
24582498
15582998
20367638
1833185
12447691
9001210
2570636
24101512
23543736
11331587
12524548
22726437
27626412
|
CDC20
|
CCNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
19652693
18590585
7575488
17303408
12124778
17660363
15279786
15917306
|
CCNB2
|
CDC25C
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
8348613
12814430
10373560
11313986
16123593
12478465
|
MYC
|
CCNE1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
18802399
20607601
14519204
22583478
9188852
11983916
11509615
|
CDKN1B
|
CCNE1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
29.0
|
1.0
|
Omnipath
|
17145710
31831640
8978686
8684460
17293600
9632134
17254967
9311993
20837141
27175940
9488039
25241761
8891332
9660939
7753174
19470470
9218599
12529437
9192873
8756624
17254966
12501191
9891079
10393546
9716181
11940657
|
CDK2
|
CCNE1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
50.0
|
1.0
|
Omnipath
|
17145710
16223725
21092281
15004009
10962581
9840943
8643455
24358021
8861947
21372285
17570479
11237742
10330164
22558078
10652300
19561641
10477583
18691976
23853094
12144826
10500095
1388288
10827081
17970072
28137908
19470470
8756624
10809788
14536078
15364936
|
CCNE1
|
CDKN1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
29.0
|
1.0
|
Omnipath
|
17145710
31831640
8978686
8684460
17293600
9632134
17254967
9311993
20837141
27175940
9488039
25241761
8891332
9660939
7753174
19470470
9218599
12529437
9192873
8756624
17254966
12501191
9891079
10393546
9716181
11940657
|
CDK1
|
CDC20
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
22.0
|
1.0
|
ACSN
|
12124778
14551205
14614141
15242590
15279786
15375219
15377654
15485915
15917306
16713580
16818604
17303408
17596790
17660363
18414028
18543256
18590585
18995830
19652693
19686080
7575488
9892021
|
CDK1
|
CDC25C
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
26.0
|
1.0
|
ACSN
|
1075565
12124778
14551205
14614141
15242590
15279786
15375219
15377654
15485915
15917306
16713580
16818604
17303408
17568790
17596790
17660363
18073536
18414028
18543256
18590585
18786381
18995830
19652693
19686080
7575488
9892021
|
TP73
|
CDC25C
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
19861536
11396965
|
TP53
|
CDC25C
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
11396965
16582636
16807237
15574328
19861536
11972334
|
CDK2
|
CDC25C
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
20530684
28396830
|
TP53
|
CDC25C
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
18431400
29302370
16753148
16713569
10853038
|
CDK1
|
CDC25C
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
64.0
|
1.0
|
Omnipath
|
17349584
17110335
17303408
18073536
1075565
11836499
15279786
8348613
7575488
20668692
24710276
9733650
12036951
20068231
8440392
12742231
32075732
16189514
9141461
16123593
18669648
19652693
18590585
9585407
12814430
10864927
10373560
18691976
11313986
12124778
18786381
17660363
18272572
8119945
15917306
27038604
9268380
17596790
28396830
17568790
19350548
16964243
10037602
18212344
12478465
12766774
|
CDK1
|
CDT1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
12.0
|
1.0
|
ACSN
|
14551205
15279786
17102137
17116885
17296725
17303408
17582221
17660363
18414028
18590585
19793801
7575488
|
TP63
|
CDK1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
11593387
19861536
|
TP53
|
CDK1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
16.0
|
1.0
|
Omnipath
|
10825186
11593387
12874009
19472317
10514438
11313928
16807237
8270002
17942917
9275177
20395210
11032828
19861536
12889596
19067706
|
TP73
|
CDK1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
19861536
11593387
19067706
|
E2F4
|
CDK1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
15510213
17671431
11799067
11032828
17121828
17531812
|
MYC
|
CDK1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
18802399
2237430
8065306
11085504
|
CKS1B
|
CDK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
26186194
19786724
9276444
9774639
23602568
20015071
25416956
7809159
18471975
26496610
25852190
16189514
|
E2F4
|
CDK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
15510213
16135806
|
PKMYT1
|
CDK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
91.0
|
1.0
|
Omnipath
|
17145710
19901323
26899266
19690332
16497976
15592455
19413330
11202906
17480229
25609063
18083107
20360007
19415658
14972559
19534553
9552418
10564259
16083285
24651440
7743995
20068231
18452278
12912980
25344910
11730318
96108162
12049736
18669648
12814430
22494620
10373560
18691976
28539822
15964826
26131711
12738781
19917613
17487921
17192257
20068230
10504341
20419782
19651622
9001210
20058876
9268380
10209160
23166842
8428596
19369195
25435947
24630986
15951569
17016520
8084605
12186947
7569953
|
CDK1
|
CDKN1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
23455152
23543736
25032860
21490307
16492801
10931950
|
CDK1
|
TP73
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
15985436
17620410
12676926
|
CDK1
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
20.0
|
1.0
|
Omnipath
|
24173284
12767922
1584757
20661218
26029996
2141171
9467949
17570479
20808790
7862459
11327730
11078726
27726420
8357826
16713569
2156209
|
MYC
|
CDK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
34.0
|
1.0
|
ACSN
|
11274345
11283614
12545156
14536078
15147722
15155580
15279786
17055429
17303408
17550342
17558397
17660363
17873522
18590585
18636226
19887899
20027199
20237412
20551172
20581311
20713526
20818389
21406394
21733352
2191300
21919891
22067385
23140366
23869868
24954210
25002027
28536364
7575488
9618481
|
MYC
|
CDK2
|
â—¼ SHARES_COMPLEX
|
|
|
34.0
|
1.0
|
ACSN
|
11274345
11283614
12545156
14536078
15147722
15155580
15279786
17055429
17303408
17550342
17558397
17660363
17873522
18590585
18636226
19887899
20027199
20237412
20551172
20581311
20713526
20818389
21406394
21733352
2191300
21919891
22067385
23140366
23869868
24954210
25002027
28536364
7575488
9618481
|
CDK2
|
CDT1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
18.0
|
1.0
|
ACSN
|
14536078
15147722
15175241
15279786
15677884
16581787
17038621
17102137
17116885
17296725
17303408
17582221
17660363
17713585
18590585
18636226
19793801
7575488
|
CDK2
|
FZR1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
10323868
10375532
16582612
12730199
|
E2F4
|
CDK2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
17531812
22447046
|
CDK2
|
FZR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
17.0
|
1.0
|
Omnipath
|
11598127
15577895
9736735
12560341
15558010
20068231
10548110
16123593
15840442
18669648
|
CDK2
|
TP73
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
22002055
15985436
12676926
|
CDK2
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
8386367
27653698
17081983
19966300
18669648
29896817
17570479
20713526
17558397
15103331
22348395
20445224
|
CDK2
|
CDKN1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
125.0
|
1.0
|
Omnipath
|
26416244
20519948
19631451
16326706
17409098
15557281
9658399
23029392
22733130
17570479
26496610
23576547
12700233
9388487
10585280
27282251
27175940
15619620
25241761
15735731
9218599
9192873
17254966
15996662
9724724
11940657
18285702
22492278
23409140
18615582
12093740
22721951
15647383
9380407
17418410
16189514
17053782
17698606
25852190
10679394
17602833
9660939
12188931
15122251
10831586
25818643
22028818
21424700
12529437
15011833
12042314
11250701
11223033
23455922
8978686
16780593
21439954
15302935
19648963
14504289
9736735
10198259
16782892
11565035
21423803
16492801
9311993
12417722
17671428
21187893
15355997
28601655
10809788
10393546
15212693
10323868
26450989
23602568
18850315
12482975
9399644
15890360
9632134
17254967
26186194
20810788
20197382
15475007
12800980
17997402
12972555
15980415
24336329
26701207
25605247
26987798
|
CDK2
|
TP63
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
21602882
18769144
|
CDK2
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
39.0
|
1.0
|
Omnipath
|
24173284
9315650
19413330
19664995
16083285
1088347
16552184
10884347
17570479
10747897
25241761
7624134
11687964
17287340
92065884
12064478
19556892
14640983
10348343
14702041
|
TP53
|
CDKN1B
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
15145945
15988033
19235838
10516009
21478095
14984207
19427386
|
TP53
|
CDKN1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
21340684
20066118
20457558
20182602
6396087
|
CKS1B
|
CDKN1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
15340381
15147722
12813041
12820959
18805092
16209941
12140288
11516665
15071497
15688063
19584057
|
E2F4
|
CDT1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
17531812
14990995
|
E2F4
|
CDT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
18319725
16144839
14990995
|
GMNN
|
CDT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
36.0
|
1.0
|
Omnipath
|
17145710
20980834
17318181
17261582
22581055
14993212
14578910
21543332
15232106
26496610
18617514
11125146
15257290
15855168
19906994
27107012
15138268
16482215
18162579
18184650
|
E2F4
|
MYC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
24573694
17132729
17699159
11689553
12757710
|
GRB2
|
KSR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
53.0
|
1.0
|
ACSN
|
10086337
10567412
10811803
10843677
10982827
11023813
11034387
11062502
11274345
11385609
11447289
11777939
11907067
12040186
12175651
12419216
12640133
12782630
14585353
14724641
14764585
15169888
15173823
15536084
15547943
15567848
15574420
15735649
15863030
16102570
16227978
16488589
16582911
16887996
17178906
17395718
17496910
17613518
17673906
19289794
19449109
19541618
19565474
19568798
19615955
21102635
22435554
24027568
26552706
7510700
8551221
8929532
9510155
|
GRB2
|
KSR1
|
â—¼ SHARES_COMPLEX
|
|
|
53.0
|
1.0
|
ACSN
|
10086337
10567412
10811803
10843677
10982827
11023813
11034387
11062502
11274345
11385609
11447289
11777939
11907067
12040186
12175651
12419216
12640133
12782630
14585353
14724641
14764585
15169888
15173823
15536084
15547943
15567848
15574420
15735649
15863030
16102570
16227978
16488589
16582911
16887996
17178906
17395718
17496910
17613518
17673906
19289794
19449109
19541618
19565474
19568798
19615955
21102635
22435554
24027568
26552706
7510700
8551221
8929532
9510155
|
GRB2
|
KSR1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
53.0
|
1.0
|
ACSN
|
10086337
10567412
10811803
10843677
10982827
11023813
11034387
11062502
11274345
11385609
11447289
11777939
11907067
12040186
12175651
12419216
12640133
12782630
14585353
14724641
14764585
15169888
15173823
15536084
15547943
15567848
15574420
15735649
15863030
16102570
16227978
16488589
16582911
16887996
17178906
17395718
17496910
17613518
17673906
19289794
19449109
19541618
19565474
19568798
19615955
21102635
22435554
24027568
26552706
7510700
8551221
8929532
9510155
|
TP53
|
HSP90AA1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
15358769
15284248
24451373
18996350
|
HSP90AA1
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
12427754
10557093
21460846
16713569
11507088
|
KMT2A
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
20677832
16510874
|
MYC
|
TP53
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
10962037
10656696
8494784
10348347
19882681
16557594
19086036
15780936
14519204
16112647
11781835
7969121
11789587
9839551
|
TP53
|
TP63
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
11.0
|
1.0
|
Omnipath
|
10606233
16931914
18388131
16516862
14576823
11382762
20442293
23019126
19858204
11238924
11423969
|
TP53
|
TP73
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
11238924
18431400
21508668
9891077
|
TP53
|
TP63
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
11238924
18431400
16713569
|
EXO1
|
UBE2S
|
â—¼ KO_UP_REGULATES
|
✅
|
+
|
1.94
|
1.94
|
PKG
|
28854368
|