Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
TFDP1 CDK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14618416
E2F4 CKS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17531812
CCNA2 CDT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17145710 14993212
TFDP1 E2F4 â—¼   PHYSICAL_INTERACTION ✅ 0.81 0.81 mint 24981860
FZR GEMI â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 29875408 11562349 21700221
CDK2 CDK1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 21319273
CDK1 GEMI â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
CDK2 E2F4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33961781 25852190
GEMI CTC1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
GEMI STN1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
GEMI E2F4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
GEMI TYK2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CKS2 CDT1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CKS1 CDT1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
GEMI SKP2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
GEMI E2F5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CKS2 GEMI â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
GEMI MSL1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
RUN3A GEMI â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
GEMI BAG4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
GEMI TRIM1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
GEMI HSP7C â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
GEMI MYO5C â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
ZN785 GEMI â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CKS1 GEMI â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
GEMI HMMR â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
GEMI NPHP3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
GEMI MTMR1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
GEMI KLH22 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
GEMI TARB1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
GEMI FA83D â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
GEMI HECD1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
TF2LY GEMI â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
PNKD GEMI â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
GEMI CERK1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
GEMI TRI18 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CDK1 CDK3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
CDK3 GEMI â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
CDK3 CDT1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
CCNA2 GEMI â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194 26496610
FZR CKS2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 33306668
CB068 GEMI â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
HMMR FA83D â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 29789297
CDK1 FZR â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 28514442 33961781 33306668 20581839
CDK2 TFDP1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 33961781 9199321 25852190
CCNA2 CKS2 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 28514442 33961781 26186194 19483727 18471975
CKS2 CKS1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 2227411 33961781 28514442
FZR CD2A1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 33306668 28628118 28205554
CDK1 SKP2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 28514442 26496610 33422522 33961781 26186194 32707033
CD2A1 GEMI â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 15232106 27229929
MCI GEMI â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 28514442 21543332
CDK2 FZR â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 28514442 33306668 11340163 12560341 23670162 26083744 33961781 23972993
CCNA2 FZR â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 28514442 31455778 33306668 27653696 31489637 21700221 18485873 26186194 33961781 19483727
CDK1 SKP2 â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
CDK2 GEMI â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 23455922 26186194 33961781
CDK3 SKP2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 26186194 23602568
FZR SKP2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 19270695 28514442 16189514 22770219 15014503 33306668 33839758 20663873 31806563 19686743 23972993 33961781 21212736 15014502
GEMI SIX3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 14973488 22615398
GEMI CC146 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 32296183 25416956 33961781 26186194
GEMI TFDP1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 27705803
CCNA2 CDT1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
CDT1 SKP2 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
CDT1 CDK1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 26186194 31160578 14993212
CCNA2 CDK3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 8626584 33961781 26186194 23602568
CDT1 FZR â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 33306668 18162579
CKS1 CCNA2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 26496610 33422522 33961781 26186194 11907280 16209941 19483727 18471975
TRIM1 TRI18 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16434393 32296183 25416956 16713569 11806752 10400985 25910212 11331580 33961781 26748699
CDK1 CDT1 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
CKS2 CDK1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 26496610 23602568 33961781 26186194 19786724 25852190 32707033 26344197 18471975
CDK1 CCNA2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 24302728 21308745 26496610 33422522 14681455 23602568 25852190 33961781 12853968 26186194 17679094 32707033 9053846 8463339 19483727
CDK3 CKS2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
STN1 CTC1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 19854130 28514442 22763445 33961781 26186194
CDT1 CCNA2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 18184650 26496610 31160578 33961781 26186194 14993212
BAG4 HSP7C â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 32296183 29568061 11909948 25036637
GEMI HXD10 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 14973489 22615398
CDK2 CDT1 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
CKS1 CDK1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 25416956 26496610 25852190 9774639 33961781 19786724 26186194 23602568 32707033 22939629 26344197 18471975
CDT1 CDK2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15004027 26496610 31160578 15855168 14993212 23455922
SKP2 CDK2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 16189514 9858587 9636170 25852190 23455922 10559858 19270695 26496610 23602568 16979657 10386600 19686743 15355997 20160477 18604603 22770219 33422522 33961781 26186194 7553852
CDK2 TFDP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12006580 11420722 9315635
E2F4 TFDP1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 32296183 16360038 9501179 8657117 7958924 7958925 10540350 27705803 9343408 24981860 9199321 7892279
E2F4 CCNA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15510213 10766737 18319725
CDT1 SKP2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12840033 15004027 18162579 26496610 31160578 15855168 14993212
SKP2 CCNA2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 9858587 26496610 27720894 33422522 16209941 33961781 24632684 15355997 26186194 7553852 31181401 20160477 10559858 33989513 18604603
SKP2 CKS1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 16189514 15772084 12140288 16338391 18239684 19786724 15980415 16979657 12813041 11463388 23589337 12529174 11231585 33422522 33961781 18519678 16209941 17409098
CCNA2 SKP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9858587 15355997 33989513
SKP2 CCNA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 9858587 15355997 33989513
E2F5 TFDP1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 7760804 27705803 24981860 7892279 9464260
CCNA2 SKP2 â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
CCNA2 CKS2 â—¼   PHYSICAL_INTERACTION 903.0 0.9 STRING 36370105
CDK2 SKP2 â—¼   PHYSICAL_INTERACTION 911.0 0.91 STRING 36370105
CDK2 CKS2 â—¼   PHYSICAL_INTERACTION 919.0 0.92 STRING 36370105
CCNA2 CDK1 â—¼   PHYSICAL_INTERACTION 929.0 0.93 STRING 36370105
CDK2 CDK3 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 28514442 23455922 26186194 33961781
GEMI HXC9 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 14973489 22615398
CDK3 CKS2 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 32296183 33961781 26186194
CKS2 CDK2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 26496610 33961781 26186194 19786724 25852190 23455922
CDT1 GEMI â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 18617514 15257290 15138268 17318181 20980834 26496610 17261582 15855168 19906994 15232106 30018425 22581055 16482215 18162579 31160578 27107012 21543332 18184650 33961781 11125146 14993212 14578910
CDK2 CCNA2 â—¼   PHOSPHORYLATION ✅ + 0.97 0.97 Signor 10652300
CDK3 CKS1 â—¼   PROTEIN_INTERACTION 0.98 0.98 HIPPIE 28514442 32296183 7809159 33961781 26186194 23602568
E2F5 TFDP1 â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
CCNA2 CDK2 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 8475101 28514442 16431923 33854235 11940657 10559988 15189033 17361108 16290148 14681455 17254966 8662825 25852190 15557281 23455922 19483727 18471975 11141566 10924145 15828833 21241890 19631451 11377199 18177895 8684460 26496610 9716181 12853968 11907280 23602568 9724724 15647383 14656438 19773423 12941338 15239650 24302728 25669885 15890360 7630397 8756328 8397207 21447625 22231403 20733051 9660939 24358021 12044161 33422522 11983168 33961781 26186194 7553852 16209941 12244298 9380407 8463339 15455144 10930425
CDK2 CKS1 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 28514442 16189514 15772084 12140288 19786724 25852190 23455922 31467278 7809159 26496610 23602568 16979657 8601310 17409098 9840943 29997244 33961781 26186194 26344197
E2F4 TFDP1 â—¼   PHYSICAL_INTERACTION 989.0 0.99 STRING 36370105
CDK1 CKS2 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
CDK1 CDT1 â—¼   ENZYMATIC_REACTION ✅ 12.0 1.0 ACSN 14551205 15279786 17102137 17116885 17296725 17303408 17582221 17660363 18414028 18590585 19793801 7575488
E2F4 CDK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 15510213 17671431 11799067 11032828 17121828 17531812
CCNA2 CDK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17145710 1833185 10924145 8423786
E2F4 CDK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 15510213 16135806
CCNA2 CDK2 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
CDK2 CDT1 â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 ACSN 14536078 15147722 15175241 15279786 15677884 16581787 17038621 17102137 17116885 17296725 17303408 17582221 17660363 17713585 18590585 18636226 19793801 7575488
E2F4 CDK2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17531812 22447046
CDK2 SKP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 7553852 20160477 23602568 25271736 18239684 28446188 23226679 10386600 19270695 26496610 16189514 25852190 26186194 25788262 9858587 22770219 15355997 10559858 23807222 22311674 16979657 9636170 19686743 19270694 18604603 23455922
CDK2 CCNA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 81.0 1.0 Omnipath 8756328 7553852 11377199 17145710 23602568 11983168 12044161 19483727 12853968 16209941 8397207 15455144 19631451 8475101 24358021 15557281 8684460 12941338 15647383 15890360 21447625 9380407 26496610 11141566 25852190 15189033 14656438 20733051 21241890 10652300 25669885 12244298 26186194 10930425 9660939 10477583 24302728 15239650 19773423 8463339 16290148 10924145 11907280 17361108 17254966 8662825 15828833 18471975 9724724 7630397 10559988 9716181 11940657 23455922
E2F4 CDT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17531812 14990995
E2F4 CCNA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17531812 17121828 21311680 15448153
E2F4 CDT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18319725 16144839 14990995
CCNA2 TFDP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 15840440 16135794 9736735 15133492 15558010 15123636 9556498 16213134 11980909 16123593