Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
E2F1 TOP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7734951
E2F1 AURKB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18319725 15033491
HIF1A MDM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12606552 15385570
MDM2 MDM4 â—¼   COLOCALIZATION 2.0 0.8 intact 17159902 5219425
VHL HIF1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218395 16511565
CDK4 CCND2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
HUWE1 CD2A1 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 28193319 26496610 15989956 26212014 22561347
CD2A1 BECN1 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 19049976 28628118 28205554
FZR GEMI â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 29875408 11562349 21700221
CD2A1 E2F1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 20106982 11314038 16135794
MYC RL11 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17599065 29467282
CDK6 HS90B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22939624 33961781
AURKB CD2A1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 29568061 31586073
PRS6A HIF1A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 14556007 16713569
CD2A1 PIAS2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 20308430 19901969
PSME3 CD2A1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17588519 31565481
CD2A1 CK5P3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28027003 16173922 23028987
RL11 P53 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22467867 23169665 23443559 15308643 31152661 32334023 14612427
NUCL RL11 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22939629 33961781 27049334
MYC FZR â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 21150319 28628118 28205554
MYC HIF1A â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 28628118 15071503 28205554
CD2A1 TOP1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 12673200 18004878 15361825
P53 AURKB â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 29340707 20959462
CDK4 P53 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 28218424 28628118 28205554
RL11 CD2A1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 22467867 14612427
CD2A1 NUCL â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 14636574 16582619
FZR CD2A1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 33306668 28628118 28205554
CD2A1 ACTG â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 22863883 17955473
CDN2B CD2A1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 24981860 28628118 28205554
CARF CD2A1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 12154087 17460193 12581788
MDM2 PRS6A â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 20479273 22659184 24583282
AURKB HS90B â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 28514442 23443559 22939624 26186194 31586073 32707033 29568061
CD2A1 HIF1A â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 28628118 11382768 28205554
CD2A1 HS90B â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 17955473 16582619
CD2A1 GEMI â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 15232106 27229929
MYC HUWE1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 17314511 16269333 26279298 18488021 29467282 31677785
NUCL MDM2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 16751805 30948704 24147044 22103682 24583282 20195357
SRTD1 CDK4 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 15065884 10580009
VHL PRS6A â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 14556007 16713569
LTOR3 CD2A1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 20655927 18479705
HUWE1 P53 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 31570706 22552282 15989956
CD2A1 MYC â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 23277542 28628118 16410719 15361884 28205554 20308430 17289033
MYC CDK6 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 22094256 28628118 28205554
MYC TOP1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 17314511 20195357 30415952 29467282
MYC NUCL â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 17314511 30415952 29467282
MYC PRS6A â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 17314511 29467282 21988832
PIAS2 P53 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 25241761 11867732 19901969 19339993 18624398
HIF1A MDM2 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
MDM4 CD2A1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 11297540 28628118 28205554
P53 TOP1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 10468612 18697815 16713569 8639538 11805286 32807901
CDK4 CDK6 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 23455922 28205554 28628118 33961781
CDK4 HS90B â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 22939624 33961781 26186194 32707033 23455922
PRS6A CD2A1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 14665636 17334400 16713569
CD2A1 P53 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 9653180 28218424 22467867 9529249 28628118 22348305 12446718 20395212 35140242 9724636 28205554 14612427
SRTD1 CD2A1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 15065884 10580009
P53 E2F1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 8557038 11739724 24076372
PIAS2 MYC â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17471507 16352593 17418410 18923429 11283613 20426839 30415952 19786833
MYC CDK4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 22094256 28205554 28628118 21988832
MYC P53 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 21150319 30415952 28628118 28205554
HIF1A P53 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15629713 16189514 11593383 9537326 16713569 12124396 31467278 12606552 10640274 27345397
HIF1A HS90B â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 20668552 19802386 18538669 26517842
VHL CD2A1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17353931 26211615 7604013 21942715
CD2A1 CCND2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11900540 15065884 28628118 28205554
PSME3 P53 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 21084564 18309296
P53 NUCL â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16189514 16713569 22103682 12138209 26238070 32807901
CD2A1 CCND1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 24855949 28042499 26496610 10580009 17420273
E2F1 MDM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10914734 20837136
E2F1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11564866 18319725 90001421
MDM4 MDM2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 10629057 32300648 25512388 21988832 25384516 25809483 17616658 25105592 12874296 31796886 29295817 32075226 20705607 17301054 22493164 25703327 27777309 29523541 27617579 23028042 20473904 22120712 22333590 22902369 22745160 12860999 19432880 21925390 28205554 25659040 19838211 33985974 16055726 25961923 32427989 18566590 22266850 18219319 29057323 10608892 30598450 29524278 25825738 17159902 24813712 31024344 27621617 15604276 29262653 19619542 10218570 28628118 16227609 10827196 12393902 24755078 20724842 34551723 27215386 11606419 20484049 12370303 23671280 26001071 26720344 33961781 12483531 23946421 19683495 26359458
HIF1A MDM2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12606552 10640274 25447306 15880652 19696166 25535359 17234751 15385570
CD2A1 MDM2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17909018 12167711 25809483 20713054 10822382 16173922 9529249 18583933 22120712 20395212 18467333 9724636 12085228 28205554 18541670 16107876 9529248 21133853 29057323 17116689 18418067 12630860 24769896 11223036 14612427 9653180 19049976 22467867 10801444 17426254 28628118 18813780 15355988 16702947 10871849
PSME3 MDM2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21084564 18309296 24583282
MDM4 P53 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 10629057 29023092 30672125 31152661 17110929 19521340 10075736 30832340 22807444 12874296 25609649 11528400 24445145 17080083 18677113 20705607 27249653 9226370 17301054 18485870 26148237 27114532 16024788 22374672 24127580 18316739 26876197 29523541 21088494 23028042 24667498 30045945 20515689 25464845 22745160 19432880 21925390 28205554 20174603 21965653 25961923 21075307 22266850 8895579 28487147 32511789 10608892 30598450 25825738 19305137 19255450 11223036 15604276 16713569 28628118 16227609 10827196 12393902 20724842 24659749 12370303 23671280 17875722 33961781 31462704 26186194 23946421 31066983 19075013 15916963 19153082
MYC TOP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
NUCL TOP1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 8567649 9512561 15848144 10967121
CDK6 CCND2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16189514 16713569 28628118 10022865 28205554 11360184 30217970 33961781 23602568 11358847 9178893
CDK6 CD2A1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 17909018 17955473 11739795 24855949 23602568 28205554 17881001 15232106 10022865 9751050 10491434 32707033 8805225 11556834 16713569 28628118 9380698 33961781 26186194
CDK6 CDN2B â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 32296183 25416956 28628118 10022865 28205554 23602568 33961781 26186194 26578655 32707033
CDN2B CDK4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 16189514 9163429 9111314 23455922 32296183 26496610 23602568 28205554 10022865 25910212 7478582 16169070 32707033 19447967 21900206 28628118 33961781 24981860 26186194
CD2A1 CDK4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 17909018 8259215 17955473 23455922 28218424 15065884 9529249 24855949 17517622 28042499 26496610 10580009 23602568 28205554 17881001 15232106 11900540 10022865 17353931 9228064 12529334 10585280 10491434 8805225 10719365 32707033 11556834 28628118 24981860 33961781 26186194
CCND1 CDK6 â—¼   PHYSICAL_INTERACTION 919.0 0.92 STRING 36370105
MDM4 MDM2 â—¼   PHYSICAL_INTERACTION ✅ 0.93 0.93 mint 15604276 5217417
MDM4 MDM2 â—¼   COLOCALIZATION ✅ 0.93 0.93 mint 17159902 5219425
CCND2 CDK6 â—¼   PHYSICAL_INTERACTION 939.0 0.94 STRING 36370105
CCND2 CDK4 â—¼   PHYSICAL_INTERACTION 949.0 0.95 STRING 36370105
CDK6 CCND1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 15232106 16713569 10022865 24855949 17517622 33854235 11739795 14681455 24953629 11360184 33961781 10580009 17420273 21654808 11160398 9178893 19075005
RL11 MDM2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 15308643 21988832 17110929 21097889 30320499 29702115 18560357 26908445 30862720 32198344 17310983 32483207 29547122 21903592 32334023 32516735 15314173 18426907 20554519 23728348 23776465 23169665 27829214 19713960 29057323 17116689 21399665 17242401 16803902 12842086 27856536 17373842 14612427 20547751 21804542 22467867 24583282 33961781 15314174 23507139 33355139 31903119
P53 MDM2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 19303885 25417702 34408321 17268548 23252402 23880345 22807444 15094782 20962272 12529318 21726810 22124327 18981217 16173922 23318437 15558054 22524527 30584071 31626714 22301280 32516735 20174603 22912717 21075307 15848166 18566590 23483203 26882543 23402884 14671306 15001357 10889512 17908790 19411846 10640350 21561866 14499615 33503543 21986495 24998844 15908921 26673821 17098746 25362358 32066565 25739118 29295817 34362424 16595680 20591429 27336364 22745160 24462112 32427887 18467333 26578655 23261415 9271120 16055726 19357310 31591476 23169665 16338390 10608892 30464405 15542844 12612087 22266868 15550400 22331460 22914926 19071110 7686617 14559824 20959462 19941302 14596917 25512388 27129163 19597489 25609649 32904724 11351297 29121928 22487680 11709713 24127580 10562557 15358376 21584881 25312347 27826076 19098711 24980433 24413661 21887275 17116689 14612427 30948704 26001071 19857530 33061576 31138778 23802716 20234175 25313037 21988832 17616658 11744695 17666403 22525275 12897156 25156994 33020477 11925449 16152627 29876924 30244831 1614537 17363365 22474335 11112690 23443559 17297477 27905468 19085961 20479273 31940492 21261729 14517261 26908445 16866370 27893708 22653443 17470788 10488081 23370271 19223463 16751805 26556313 10734067 19411066 11223036 27856536 14704432 20124408 24240685 24842904 32901886 22948151 19234109 35140242 21084285 32894144 17848574 22737255 10561590 25168242 10435614 11697899 25543083 21572037 22920093 18604177 32874188 22659184 17591690 16845383 22444248 31239268 25283148 26186194 24200963 23826318 7689721 20047188 24314634 12167711 15308643 17318220 21857681 11431470 18815136 15950904 20705607 17525743 26876197 31177307 9529249 22374672 12915590 33650658 10601022 20837658 18223694 30097011 28205554 32334023 15247280 23776465 21268072 27308622 11713288 18234963 9582019 18784078 29487367 23776060 11713287 20484049 26720344 9131587 30109812 33961781 24361594 32807901 31066983 15824742 11562347 21454483 22157679 21088494 11070080 22575647 22083959 26540344 15210108 18332869 32528731 18172499 11094089 21132010 16414131 10827196 27031960 10892746 15280377 16023600 18665269 10202144 15058298 29549180 16212962 16905769 11278372 20657550 9809062 15295102 26238070 22391559 18061646 17310983 18485870 9278461 21925390 20659896 9824166 23150668 25637791 30598450 19160491 28605833 12690203 22467867 31594538 11572869 11384992 11486026 27807478 17936559 30679555 16678796 30252118 31652301 15144954 22411991 22084066 30175854 21478269 27543608 16624812 17290220 32097779 17301054 20694676 11714701 24667498 20395212 16547496 12381304 8058315 22266850 29755129 22085928 17159902 10196247 21316347 27886165 27215386 25384516 7926727 16964247 19081178 32198344 11046142 28549433 26350565 31533005 12867035 10321734 19590512 22991965 25277184 24207125 18541670 19166840 25103245 30320919 26883110 20235143 17139261 11597128 21071676 19568783 18813780 19805293 17056014 17989425 21317885 17234751 20588255 21170087 10347217 11839577 25954860 21060154 24926618 21750659 16331255 29269425 27811966 19305137 24659749 9450543 23201157 30879903 16870621 28362432 21149449 20570896 23609977 33765973 27106262 33355139 34040386 22588298 22389628 19033382 18264029 27462439 31092600 12208736 17369817 28082682 16579792 23246961 20708156 15013777 21465263 28542145 23572512 19483087 31665549 22975381 17438265 15604276 11178989 24488098 16432196 22227409 28628118 30005830 20639885 20847049 9363941 31406141 19816404 26475964 29899406 16861890 30320499 20660730 19332559 14702041 11284721 18316739 19837670 25464845 12426395 10681559 17302414 16107876 22510990 15154850 21098709 19106616 10722742 19188367 22366412 29524278 21084564 23134341 25624478 30455251 20173098 12620407 9223638 16713569 17426254 31647545 10766163 30454706 21471462 24621507 23652204 19153082 8875929 31152661 18309296 31968249 31796886 15122315 30532073 10980696 17080083 15064742 11285227 29547122 21965653 33495326 23728348 15242646 17347673 12842086 12944468 19255450 23671280 22916255 17875722 30355102 14741215 23946421 20591651 15053879 28514442 25241761 24567357 16215989 19656744 30832340 22262183 27249653 26203195 16857591 15313915 15933712 28223335 20542919 12552135 24643130 27282385 20080206 28553961 22819825 33579943 16159876 9724739 17380154 22318540 29997244 29670376 22103682 22032989 28394340 31903119
HIF1A VHL â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 15082527 11865071 11226425 10944113 14556007 11986208 15527772 17973296 12538644 26735336 24899725 12606543 21358672 24015760 16611863 23401859 18062927 21332579 15805242 19940151 12086861 27281823 23413029 33060856 11292862 24316222 16155211 24857547 22932900 29121446 11292861 12101228 15060148 18047470 16278378 21602890 27320910 12464182 26611735 32589900 18402654 25500545 12050673 18694926 26215701 10878807 25361009 11641274 22351759 34007068 18305400 21316481 11024059 34195792 26037477 34174286 33039559 10823831 26743088 31810986 10353251 15833858 17558023 11566883 23580587 27563096 18985005 19123984 25438054 12682018 18323857 23387829 17442832 33550096 18222538 18426857 17047048 12004076 34230460 23318261 33961781 12808024 21335603 12586829 17353276 11358837 28514442 20724477 16140212 12205091 20049704 16862177 11331613 32535973 15721254 14691445 15385570 10973499 15611064 17981124 28775317 12925778 26496610 17339318 30237125 20458141 20639890 17986458 19147576 28425505 11504942 22369643 18264140 16511565 12351678 14600153 30988076 17132228
CCND1 CDK4 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 28514442 25416956 25241761 8259215 9372967 29142209 9150368 18537972 16431923 33854235 24292678 9178893 33854239 9106657 14681455 8867812 8662825 17420273 19767775 16985050 19075005 12519773 21306487 26203195 24855949 23007395 11360184 10580009 11463845 17081987 8978686 16613857 15681588 21242975 15232106 9837900 24218572 27130439 10022865 25910212 9228064 12036906 23707388 23543736 27107012 23718855 19470470 31217276 10908655 8756624 25502805 17205132 33961781 20837141 19237565 21654808 11160398 7568034
CCND2 CDK4 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 28514442 16189514 14681455 32296183 9325318 11360184 30217970 28205554 15169570 10022865 17873913 25910212 27107012 28628118 33961781 26186194 11896535 9178893 11971966
CCND1 CDK4 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
MDM2 MDM4 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
HIF1A CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23455892 20360945 20179204 15991006
MYC CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 7526316 21933022 17881732 12835716 14757441 19086036 8552398 19698176 19786833 18809243 18806825 8196642 11085504
E2F1 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 10504464 7929342 22768064 19876926 20220142 9584162 17998543 20655656 8618861 8137237 23078099 23543735 10594784
MYC CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 8425218 15121849 2006410 17873522 21406394 12584560 17558397 20551172 15814658 16908182
CCND1 CDK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 63.0 1.0 Omnipath 26203195 17145710 8978686 12036906 23562856 25416956 16985050 23707388 19767775 9837900 17517622 19237565 9372967 25502805 23718855 9228064 7736585 15232106 11360184 20837141 21306487 25910212 25241761 27107012 9150368 18537972 9178893 31217276 8867812 10580009 23007395 11160398 19470470 19075005 9106657 8259215 10908655 8756624 23543736 24855949 7568034 24218572 8662825 31515488 17205132
CCND1 CDK6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 19075005 17517622 9178893 11739795 24855949 15232106 16713569 11360184 10580009 11160398
CCND1 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 9190208 10498883 18590585 7575488 9315635 17303408 10385618 10778858 9736735 16236519 20068082 7736585 9425340 11520855 19075565 18786381 17660363 15279786
E2F1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 8208548 2721961 7753559 11705881 24038073 8355712 1549358 1567856 12629508
CDK6 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 9190208 10498883 18590585 7575488 9315635 17303408 10385618 10778858 9736735 16236519 20068082 7736585 9425340 11520855 19075565 18786381 17660363 15279786
CCND2 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 9190208 10498883 18590585 7575488 9315635 17303408 10385618 10778858 9736735 16236519 20068082 7736585 9425340 11520855 19075565 18786381 17660363 15279786
CDK4 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 9190208 10498883 18590585 7575488 9315635 17303408 10385618 10778858 9736735 16236519 20068082 7736585 9425340 11520855 19075565 18786381 17660363 15279786
HUWE1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 26279298 16915296 34761308 16969074
MYC MDM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15655352 12695333 19649205 10348347
MDM2 MDM4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 69.0 1.0 Omnipath 17145710 10218570 17616658 16511560 22266850 12874296 21925390 25825738 21988832 25512388 16227609 22493164 22902369 25659040 18219319 12963717 15604276 18566590 12370303 19838211 26359458 27617579 25809483 34551723 10608892 23028042 22120712 25703327 12860999 32300648 16055726 24813712 17301054 12483531 23671280 17159902 27621617 25105592 20484049 20724842 27215386 10827196 26001071 11606419 23946421 19683495 20705607 24755078 25384516 20473904 12393902
MDM2 HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 15880652 25535359 12606552 25447306 17234751 19696166 10640274
MYC HIF1A â—¼   ENZYMATIC_REACTION ✅ 22.0 1.0 ACSN 10432118 11274345 11283614 11875494 16327802 17558397 17873522 20027199 20237412 20551172 20581311 20713526 21093321 21372296 21406394 21765015 2191300 22067385 22461508 23124025 23390297 25002027
HIF1A MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 20404562 23059786 19845622 18616527 15780936 21303984
MYC PIAS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21811581 22053792 12545156 17471507
MYC CCND2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 7526316 11511535 10508165 9339900 15988028 20857481 11060032 14519204 14660677 10956386 21790895 11264343
MYC VHL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22286234 12695333
MYC CDK4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 15208653 12835716 24951594 21384303 14519204 22395148 10688915 17728244 11983916 18414489
MYC CDK6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20682794 22395148 12835716
MYC CCND2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 8425218 15121849 11602341 2006410 17873522 21406394 12584560 17558397 20551172 15814658 16908182
MYC CDK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 21988832 11602341 17093053 22094256
CCND2 CDK6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10477583 17517622 16713569
HIF1A VHL â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
VHL HIF1A â—¼   ENZYMATIC_REACTION ✅ 19.0 1.0 ACSN 10973499 11900249 12351678 12648680 12820959 15340381 15459660 15652751 15688063 15703371 15721254 16697054 17884153 18931676 18985005 19622404 19686080 19809470 19847258
HIF1A VHL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 12205091 15930297 21887475 22150821 22396654 15962286 23159849 17482131 17140440 16883594
VHL HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 123.0 1.0 Omnipath 17145710 21332579 24857547 12682018 26496610 11292861 11024059 15060148 16278378 12586829 17353276 12004076 12205091 17339318 10823831 11226425 21602890 16862177 15611064 12351678 16140212 11865071 26037477 16611863 10973499 23401859 25361009 11331613 18305400 25438054 14691445 17047048 12538644 22932900 18985005 26735336 21358672 18323857 10878807 19147576 16511565 17973296 23413029 24316222 11986208 12808024 12464182 23318261 22369643 19940151 15721254 20724477 21335603 16391536 23387829 18694926 26743088 14556007 18264140 10353251 15082527 11358837 11292862 11566883 12050673 19123984 17558023 27281823 15805242 11641274 25500545 34174286 24899725 12606543 32535973 17132228 24015760 12086861 11504942 35589690 26215701 22351759 12925778 18222538 17986458 14600153 10944113 23580587 26611735 18426857 20049704
CCND2 CDK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 25910212 17517622 27107012 11896535 10477583 9325318 31515488 16189514 32296183