Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
UBA52 ZRANB1 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
ZRANB1 UBC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19373254 7288828
UBC ZRANB1 â—¼   DEUBIQUITINATION ✅ 2.0 0.8 intact 19373254 7288828
UBE2D3 GNB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
GNB2 UBE2S â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
GNB2 UBE2C â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
GNB2 UBE2T â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RPS27A SRP68 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
SRP68 UBA52 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
PTEN YAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
AKT1 CDKN1B â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12244303 11231573
AKT1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17942906 9804616
ANAPC1 UBE2C â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
FZR1 ANAPC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
ANAPC5 ANAPC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
CDC16 ANAPC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
CDC23 ANAPC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
ANAPC4 ANAPC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
ANAPC2 ANAPC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
CDC27 ANAPC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
ANAPC1 FZR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
ANAPC1 ANAPC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
ANAPC1 ANAPC5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
ANAPC1 CDC27 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
ANAPC1 ANAPC4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
ANAPC1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 8638126 9556553
ANAPC1 CDC23 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
ANAPC1 CDC16 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
ANAPC2 UBB â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
ANAPC2 RPS27A â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
ANAPC2 UBA52 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
CDC23 ANAPC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
ANAPC5 ANAPC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
ANAPC7 ANAPC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10922056 10500174
ANAPC4 ANAPC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
CDC16 ANAPC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
ANAPC2 ANAPC4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
ANAPC2 CDC23 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
ANAPC2 ANAPC5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
ANAPC2 ANAPC7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10922056 10500174
ANAPC2 CDC16 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
FZR1 ANAPC4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
CDC16 ANAPC4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
ANAPC5 ANAPC4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
CDC23 ANAPC4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
ANAPC4 FZR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
ANAPC4 CDC23 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
ANAPC4 ANAPC5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
ANAPC4 CDC16 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
CDC16 ANAPC5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
FZR1 ANAPC5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
CDC23 ANAPC5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
ANAPC5 FZR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
ANAPC5 CDC23 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
ANAPC5 CDC16 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
ANAPC7 UBE2C â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
CDC20 ANAPC7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10318877 12956947
CDC16 ANAPC7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10318877 10500174
CDC27 ANAPC7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10922056 10500174
ANAPC7 CDC16 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10318877 10500174
ANAPC7 CDC27 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10922056 10500174
ATXN3 UBA52 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
AURKA CDKN1B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1001737 24358021
CDC20 CDC16 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12196507 9628895
FZR1 CDC23 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
CDC23 FZR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
MYC CDKN1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 24704206 26701207
MYC CKS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11085504
CTNNB1 VHL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16983094 0606850103
UBC CYLD â—¼   DEUBIQUITINATION ✅ 2.0 0.8 intact 19373254 7288828
XRCC5 DDB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20368362
EGR1 UBC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12903198 18174897
EGR1 UBE2S â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18780286
EGR1 PTEN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12384981
MYC HERC5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11983916
HSPA1L NFKBIA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPA5 TBK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPA5 UBE2V1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HSPA5 NFKBIA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
UBB HSPA8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
HSPA8 TBK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPA8 NFKBIA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
KANSL3 RPS27A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
NFKBIA UBC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219675 17318178
UBA1 OTUB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
UBC OTUB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11689694 5214752
OTUB1 UBB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
OTUD7B UBA52 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
PBK PTEN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 24012691
UCHL3 RPS27A â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 26235645 9521656
RPS27A USP7 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 26235645 9521656
UCHL3 RPS27A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17145710 26235645
USP7 RPS27A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17145710 26235645
UBB STAMBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
STAMBP UBC â—¼   DEUBIQUITINATION ✅ 2.0 0.8 intact 19373254 7288828
UBC TBK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18636086 6804508
UBA52 USP2 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
UBA52 USP21 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
UCHL3 UBA52 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 26235645 9521656
UBA52 USP7 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 26235645 9521656
USP7 UBA52 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16713569 26235645
UCHL3 UBA52 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16713569 26235645
UBA6 UBC â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
UBA6 UCHL3 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
UBB USP5 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 26235645 7851534
USP5 UBB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 26235645 16007098
USP2 UBC â—¼   DEUBIQUITINATION ✅ 2.0 0.8 intact 19373254 7288828
UBC USP15 â—¼   DEUBIQUITINATION ✅ 2.0 0.8 intact 19373254 7288828
UBC USP5 â—¼   DEUBIQUITINATION ✅ 2.0 0.8 intact 19373254 7288828
UBC USP5 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 26235645 7851534
UBE2C UBE2V1 â—¼   PHYSICAL_INTERACTION 801.0 0.8 STRING 36370105
CDC16 CDC23 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
PTEN USP7 â—¼   PHYSICAL_INTERACTION 806.0 0.8 STRING 36370105
CYLD UBC â—¼   PHYSICAL_INTERACTION 808.0 0.8 STRING 36370105
OTUD7B UBB â—¼   PHYSICAL_INTERACTION 808.0 0.8 STRING 36370105
UBE2S FZR â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 25306923 32905768 19822757 23708001 25306918
FZR UBE2C â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 21700221 23707760 25306923 23670162 32905768 19822757 18485873
FZR CDC20 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 23643811 16287863 17403670 23091007 33306668
MDM2 AKT1 â—¼   PHOSPHORYLATION ✅ 0.81 0.81 mint 5217292 15527798
AKT1 MDM2 â—¼   PHOSPHORYLATION ✅ 0.81 0.81 mint 5217292 15527798
UBE2C CDC20 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 17443186 29735662 34382737 32152539 19820702
MDM2 CDKN2A â—¼   PHYSICAL_INTERACTION ✅ 0.81 0.81 mint 7989562 20713054
MDM2 XRCC6 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 24147044 24583282 18784078 19247369
UBE2S VHL â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 32814053 30903204 27685940 32328410
UBA52 USP5 â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
CDC27 UBE2C â—¼   PHYSICAL_INTERACTION 816.0 0.81 STRING 36370105
OTUB1 UBE2D3 â—¼   PHYSICAL_INTERACTION 817.0 0.81 STRING 36370105
MYC RPS27A â—¼   PHYSICAL_INTERACTION 819.0 0.81 STRING 36370105
TRI25 UBE2S â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22939629 29117863
YAF2 UBB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
YAF2 MDM2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
YAF2 UBE2S â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
LRC4C UBE2S â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CDC20 AURKA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 10377410 22340593
MYC UBA1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21150319 29467282
MYC XRCC5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17314511 29467282
ANAPC4 UBE2C â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
ANAPC5 UBE2C â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
UBB ZRANB1 â—¼   PHYSICAL_INTERACTION 823.0 0.82 STRING 36370105
CDC23 UBE2C â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
RPS27A STAMBP â—¼   PHYSICAL_INTERACTION 825.0 0.82 STRING 36370105
RPS27A UBE2S â—¼   PHYSICAL_INTERACTION 829.0 0.82 STRING 36370105
SRP68 FZR â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 33306668
FZR CKS2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 33306668
CK074 UBE2S â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
CDC16 UBE2C â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
EP300 VHL â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
MDM2 NCL â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
FZR AKT1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 28205554 28628118 33306668
MYC FZR â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 21150319 28205554 28628118
TACC3 FZR â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 19823035 25375378
AKT1 AURKA â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 24412244 28205554 28628118
EP300 XRCC6 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 21988832 15023334 33742100
AKT1 CDKN1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 0.84 0.84 Signor 18423396
FZR1 UBE2S â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
UBB UBC â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
DDB2 UBE2T â—¼   KO_DOWN_REGULATES ✅ - -0.85 0.84 PKG 28854368
UBA52 UBE2S â—¼   PHYSICAL_INTERACTION 845.0 0.84 STRING 36370105
UBB USP5 â—¼   PHYSICAL_INTERACTION 845.0 0.84 STRING 36370105
BIRC2 UBB â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
ANAPC2 UBC â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
ANAPC5 FBXO5 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
ANAPC7 FBXO5 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
MDM2 UBA52 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
RPS27A UBA6 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
CFTR XRCC5 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 26618866 29924966 31324722
EGR1 EP300 â—¼   PHYSICAL_INTERACTION 850.0 0.85 STRING 36370105
UBC MDM2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 18566590 19166840 17290220 19098711
AKT1 PTEN â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
MDM2 UBB â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
RPS27A ZRANB1 â—¼   PHYSICAL_INTERACTION 853.0 0.85 STRING 36370105
UBB USP21 â—¼   PHYSICAL_INTERACTION 853.0 0.85 STRING 36370105
CDC20 FZR1 â—¼   PHYSICAL_INTERACTION 858.0 0.85 STRING 36370105
RBCK1 UBE2D3 â—¼   PHYSICAL_INTERACTION 859.0 0.85 STRING 36370105
FZR AURKA â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 17895985 28205554 30498084 28628118
ANAPC1 FBXO5 â—¼   PHYSICAL_INTERACTION 860.0 0.86 STRING 36370105
RNF8 UBE2D3 â—¼   PHYSICAL_INTERACTION 860.0 0.86 STRING 36370105
ATXN3 UBB â—¼   PHYSICAL_INTERACTION 861.0 0.86 STRING 36370105
USP5 UBC â—¼   CLEAVAGE ✅ + 0.86 0.86 Signor 26235645
RPS27A USP2 â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
CDC20 FBXO5 â—¼   PHYSICAL_INTERACTION 869.0 0.86 STRING 36370105
MYC EP300 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 12776737 16287840 32140074 15616592 16126174 17157259
MYC UBC â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 21150319 16996503 19131971
UBE2D3 OTUB1 â—¼   PHYSICAL_INTERACTION ✅ 0.87 0.87 mint 8379996 22124327
RNF7 UBE2D3 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
UBA52 USP7 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
CFTR HSPA8 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
EP300 MDM2 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
RPS27A USP21 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
AKT1 CDKN1B â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
CDC20 UBC â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
OTUD7B RPS27A â—¼   PHYSICAL_INTERACTION 879.0 0.87 STRING 36370105
RBCK1 UBC â—¼   PHYSICAL_INTERACTION 879.0 0.87 STRING 36370105
CDC20 UBE2S â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
CDKN2A MYC â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
TBK1 CYLD â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 18636086 25923723 29755980
UBC USP15 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
XRCC5 ZRANB1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
AKT1 EP300 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
CDC27 UBE2S â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
ANAPC11 CDC20 â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
UBB USP2 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
HSPA8 LRRK2 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
FZR CDC27 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 21768287 29700288 11340163 23160376 26963853 9637688 32345958 23670162 12097298 21186364 12797865 17187060 32152539 17609108 25306918 22014574 33306668 12956947 16479161 24100295 23029392 9734353 21986944 20395298 24811168 28514442 30498084 17942546 20663873 21241890 9811605 32076268 18372912 18662541 23972993
MYC XRCC6 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 30415952 17314511 29467282
UBC UBE2D3 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
EXO1 UBE2C â—¼   KO_UP_REGULATES ✅ + 0.89 0.89 PKG 28854368
PARK2 UBE2D3 â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
UBA1 UBE2D3 â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
UBA1 UBE2S â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
AKT1 MDM2 â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
MYC AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16846534 16489011 18562319
ANAPC11 UBE2C â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 31942069 11739784 25959309
FZR1 ANAPC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9811605 10500174
ANAPC2 FZR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9811605 10500174
CDC27 ANAPC4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 25383541 10500174
ANAPC4 CDC27 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 25383541 10500174
CDC27 ANAPC5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16189514 10500174
ANAPC5 CDC27 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16189514 10500174
AURKA KIF11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15630414 17939994
AURKA NFKBIA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 23993973 17308110
CDC20 CDC16 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 9628895 12956947 20360068 26811472 24100295 26496610 23007648 24464857 18997788 12196507 27114510 25306918 23443559
CDC23 CDC16 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10318877 10500174
CDC16 CDC23 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10318877 10500174
CDC27 CDC23 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 22280307 16364912 22939629 26496610 20686030 26344197 27114510 32152539 10922056 20360068 12956947 22193957 14657031 17942546 27173435 16648845 32076268 22792066 32934012 21043528
CDC27 CDC23 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17145710 10500174
CDC23 CDC27 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17145710 10500174
HSPA8 CFTR â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 25961502 2799391 2204156
EP300 EGR1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 9806899 20089040 15225550 20018936
MDM2 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 9809062 11070080 16713569
MYC HSPA8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11983916 12695333
TRIM28 MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16107876
MYC UBA52 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC UBE2C â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840 22170434
UBA1 UBE2C â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
UBA1 UBB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17597759 24816145 21209336
UBE2D3 UBA52 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
XRCC6 XRCC5 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 24981860 22939629 15367688 26496610 26774286 21172662 11196700 15520013 22863883 21679440 17159921 30021884 14681455 26446488 26344197 10207052 30585729 17308091 11493912 10757784 10219089 10984620 19118032 12145306 32296183 28035050 19177010 18809223 21454661 15910003 10783163 28514442 21070772 25574025 15023334 7699019 10750018 10446239 22451927 33005030 9488450 17283121 19906305
PARK2 UBA52 â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
AURKA TACC3 â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
CDKN2A MDM2 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
PARK2 RPS27A â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
MDM2 UBE2D3 â—¼   PHYSICAL_INTERACTION 919.0 0.91 STRING 36370105
MDM2 USP7 â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
UBA1 UBB â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
STAMBP UBC â—¼   PHYSICAL_INTERACTION 929.0 0.92 STRING 36370105
XRCC5 XRCC6 â—¼   CORRELATES + 0.92 0.92 CCLE 31978347
CTNNB1 EP300 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
ANAPC4 FBXO5 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
ANAPC11 UBE2S â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
ATXN3 RPS27A â—¼   PHYSICAL_INTERACTION 934.0 0.93 STRING 36370105
ANAPC1 ANAPC11 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
AURKA TACC3 â—¼   PHOSPHORYLATION ✅ + 0.93 0.93 Signor 17545617
CDC20 UBE2C â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
FZR1 UBE2C â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
UBB UBE2S â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
CDC23 FZR â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 33961781 12956947 20360068 26496610 31420536 28514442 33306668
CDC16 FZR â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 33961781 12956947 20360068 26496610 31420536 28514442 33306668
UBB USP7 â—¼   PHYSICAL_INTERACTION 940.0 0.94 STRING 36370105
DDB2 UBE2S â—¼   KO_DOWN_REGULATES ✅ - -0.95 0.94 PKG 28854368
UBA52 UCHL3 â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
OTUB1 UBC â—¼   PHYSICAL_INTERACTION 944.0 0.94 STRING 36370105
RPS27A USP5 â—¼   PHYSICAL_INTERACTION 944.0 0.94 STRING 36370105
RPS27A USP7 â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
ANAPC11 CDC23 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
UBA1 UBA52 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
UBB UCHL3 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
RPS27A UBB â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
RPS27A UBC â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
UBA52 UBB â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
UBA52 UBC â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
PARK2 UBB â—¼   PHYSICAL_INTERACTION 957.0 0.95 STRING 36370105
XRCC5 XRCC6 â—¼   PHOSPHORYLATION ✅ 0.96 0.96 mint 10783163 5212534
ANAPC2 UBE2C â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
BIRC2 UBC â—¼   PHYSICAL_INTERACTION 967.0 0.96 STRING 36370105
RPS27A UBA1 â—¼   PHYSICAL_INTERACTION 968.0 0.96 STRING 36370105
MDM2 UBC â—¼   PHYSICAL_INTERACTION 969.0 0.96 STRING 36370105
CDC23 FBXO5 â—¼   PHYSICAL_INTERACTION 970.0 0.97 STRING 36370105
USP7 MDM2 â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 6799761 18566590
CDC27 FBXO5 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
CDC16 FBXO5 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
FBXO5 FZR1 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
MDM2 RPS27A â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
OTUD7B UBC â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
ANAPC2 FBXO5 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
EXO1 CKS2 â—¼   KO_UP_REGULATES ✅ + 0.97 0.97 PKG 28854368
RPS27A UCHL3 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
UBC UBE2S â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
ANAPC5 ANAPC7 â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
ANAPC5 CDC20 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
UBC ZRANB1 â—¼   PHYSICAL_INTERACTION 979.0 0.97 STRING 36370105
ANAPC1 ANAPC7 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
ANAPC5 CDC23 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
UBC USP7 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
ANAPC7 CDC23 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
UBC USP21 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
ANAPC7 CDC16 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
ATXN3 UBC â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
XRCC4 UBE2S â—¼   KO_UP_REGULATES ✅ + 0.98 0.98 PKG 28854368
ANAPC4 CDC20 â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
ANAPC5 CDC16 â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
UBC USP5 â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
ANAPC2 CDC20 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
UBC USP2 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
UBA1 UBC â—¼   PHYSICAL_INTERACTION 989.0 0.98 STRING 36370105
ANAPC1 CDC20 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
ANAPC11 CDC16 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
ANAPC11 FZR1 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CDC20 CDC23 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
RPS27A UBA52 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
PARK2 UBC â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
ANAPC1 CDC23 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
ANAPC1 CDC16 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
ANAPC11 UBE2C â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
CDC16 CDC23 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
CDC16 CDC20 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
UBC UCHL3 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
ANAPC1 ANAPC2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ANAPC1 ANAPC5 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ANAPC1 CDC27 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ANAPC1 ANAPC4 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ANAPC11 CDC27 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ANAPC11 ANAPC4 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ANAPC11 ANAPC2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ANAPC2 ANAPC5 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ANAPC2 FZR1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ANAPC2 ANAPC7 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ANAPC2 ANAPC4 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ANAPC2 CDC27 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ANAPC2 CDC16 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ANAPC4 ANAPC7 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ANAPC4 ANAPC5 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ANAPC4 CDC16 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ANAPC4 FZR1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ANAPC4 CDC27 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ANAPC5 FZR1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ANAPC5 CDC27 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ANAPC7 FZR1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ANAPC7 CDC27 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ANAPC7 CDC20 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CDC16 CDC27 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CDC23 CDC27 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
XRCC5 XRCC6 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ANAPC1 FZR1 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
ANAPC2 CDC23 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
ANAPC4 CDC23 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
CDC16 FZR1 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
CDC20 CDC27 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
CDC23 FZR1 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
CDC27 FZR1 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
AKT1 MDM2 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 11154281 11715018 11923280 15169778 17680028 20214616 20398329
PTEN AKT1 â—¼   DOWN_REGULATES ✅ - 22.0 1.0 ACSN 10753747 11747822 12040186 15721744 16288286 16982858 17218262 17409395 19440036 19847259 19945467 20609352 21084277 22179046 22465479 23732914 24030100 24254977 25364523 26597054 27328425 27572739
TBK1 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 21329883 21464307 21106850
LRRK2 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 24916379 21658387
AKT1 UBE2S â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 29562639 27593939
AKT1 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 17623675 18182168 16926151 20333651 19158375 17964260 17570479 11116148 25904863 21901101 23275565 16024795
AKT1 PTEN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 23.0 1.0 Omnipath 19903340 15987703 10790335 20596030 10592173 20605778 10866658 12077256 11035045 16107342 12297295
AKT1 CDKN1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 69.0 1.0 Omnipath 22119715 11756412 16780593 11923280 16697215 16209941 12244303 20398329 18372248 14967450 18710949 15808505 26053093 20138985 14504289 20214616 12244302 17570479 18593906 23576547 23400686 12851486 15169778 24651496 19829074 25241761 10949026 16288292 11715018 18636226 19377290 9812896 12042314 17680028 10722653 20832730 18570873 12244301 17052453
AKT1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 20858269 23331499 20028971 11882383 21303971 17680028 20214616 22094462 17287208 17374729 20398329 21506126 21402455 12040186 19623618 12063252 18218901
AKT1 PDCD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 17053147 17081983 18296647 18187866 17287340 16357133 16964243 18669648
AKT1 MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 60.0 1.0 Omnipath 11756412 11923280 20856200 20452955 20398329 18332867 19664995 10217147 11154281 19216069 20214616 11463845 19166854 15527798 9829964 17570479 16680151 17646672 12145204 15169778 15140942 25241761 11715018 25209720 17680028 21930127 11504915 29311840 15574337 23397142
CDC20 ANAPC11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 25241761 27509861 18997788 26387737 9734353
ANAPC2 ANAPC11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12956947 24163370 11739784 10230407
FBXO5 ANAPC11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 7575488 18590585 17303408 16439210 16921029 17660363 15279786
ANAPC11 ANAPC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12956947 24163370 11739784 10230407
CDC27 ANAPC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17145710 10922056 10500174
ANAPC2 UBE2C â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 25825779 16189514 11739784
ANAPC2 CDC27 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17145710 10922056 10500174
FBXO5 ANAPC7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 7575488 18590585 17303408 17660363 11751633 15279786
MYC AURKA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20890087 20519624 14744757 20682043
AURKA DLGAP5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 15987997 18220336 16631581 19690332 18669648
AURKA TACC3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 23861900 31932847 25596274 26186194 17060449 21297582 20566684 14602875 17545617 23918938 16172205 15687499 30344944 26090906 26134678
CDC14B FZR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19680264 18662541
CDC27 CDC16 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 17145710 9405394 17187060 24100295 7736578 21043528 10922056 26496610 9356466 25306918 12956947 20733055 22193957 27114510 16648845 9628895 14657031 20360068 16364912 10500174
CDC16 CDC27 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 17145710 9405394 17187060 24100295 7736578 21043528 10922056 26496610 9356466 25306918 12956947 20733055 22193957 27114510 16648845 9628895 14657031 20360068 16364912 10500174
CDC27 CDC20 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 25156254 12956947 9736712 17443186 22014574 9637688 24781523 16189514 14561775 12196507
FBXO5 CDC20 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 7575488 18590585 11988738 17303408 11389834 15678131 16189514 17660363 11976684 15279786
CDC20 CDC27 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 25156254 12956947 9736712 17443186 22014574 9637688 24781523 16189514 14561775 12196507
FZR1 CDC27 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 12797865 12956947 23029392 18662541 9637688 15916961 22014574 21241890 10500174 26963853
CDC27 FZR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 12797865 12956947 23029392 18662541 9637688 15916961 22014574 21241890 10500174 26963853
EP300 CDKN2A â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 32284348 19273602 32601262 10821856 28985506 33043019 31597407
MYC CDKN2A â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 11274345 11283613 11283614 11704864 15199070 17055429 17558397 17873522 20027199 20237412 20551172 20581311 20713526 21406394 2191300 22067385 25002027 28536364 9694806
MYC CDKN2A â—¼   ENZYMATIC_REACTION ✅ 19.0 1.0 ACSN 11274345 11283613 11283614 11704864 15199070 17055429 17558397 17873522 20027199 20237412 20551172 20581311 20713526 21406394 2191300 22067385 25002027 28536364 9694806
MYC CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 15361884 11593429 11507042 20023701 23342141 16537449 23277542 10914736 9212167 12835716 24177224 11062467 15199070 18762810 19786833 20551174 11360201 23722468
MYC CDKN2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 15361884 9308237 10373560 17936558 12209154 12738781 17873522 11283613 21406394 9312026 15095404 17558397 20551172 19901969 19815509 10504341
CDKN2A MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 57.0 1.0 Omnipath 12167711 18541670 23416275 9529249 17426254 12630860 17116689 12085228 15856024 10822382 19166854 12209154 12740913 17158541 16915296 17909018 25809483 9653180 14612427 22120712 16173922 10871849 18418067 24769896 9724636 21133853 10801444 19049976 9529248 16107876 18813780 20713054 18467333 15355988 18583933 20395212 11223036
HSPA8 CFTR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 21148293 10666020 19878303 21697503
CTNNB1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 21533051 19778454 16510874 12095419 17360646 18852287 15576399 19561604 20300972 19662654 15579438 17724465 9727977 24447505 18679417 12907606
EP300 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 11050151 18987336 15806138 15060161 17410209
CTNNB1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 19751508 7542250 11967263 22290435 19623618 16574648 23343194 11955436 22270359 22761862 16039586 15810077 17143292 12051714 8666229 22943793 15576399 21151179 16940750 17306568 17666529 21285352 19619488
RBCK1 CYLD â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 26997266 27591049 27545878 24098568 27458237 27307491 22435550
EGR1 EP300 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20414733 18798221 15635605 15225550
EGR1 PTEN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 17330857 17479230 20514024 12917634 17516844 15231710 18062928 18324520 11781575 20862322 16138117 21297666 20959484 16424010 15517593
EP300 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 17145710 22290435 19623618 11804596 23343194 22761862 16039586 12776737 17157259 17143292 12660246 15576399 21151179 15522869 17306568 19407812 17666529 21285352 19619488
FBXO5 FZR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 11751633 16439210 16189514 11988738
MYC IGF2BP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21779431 18414489 21252116
MYC MDM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15655352 12695333 19649205 10348347
NCL MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 24147044 16751805 22103682 20195357
USP7 MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 36.0 1.0 Omnipath 17145710 17936559 26460617 15916963 24462112 22056774 18566590 20816748 16402859 20713061 16943424 17380154 29236775 16082221 26238070 34799561 16845383 16474402 28406480 27452404 28196907
MDM2 UBB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19805293 22056774 17290220
MYC PTEN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23135913 19578399 12695333
MYC NCL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10606642 24951594 12695333 14519204 25018006 11983916
MYC VHL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22286234 12695333
PPP2R5A MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 19131971 10026142 10995457 18042541 18559511 16680151
UBE2D3 NFKBIA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 10329681
TBK1 NFKBIA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 25.0 1.0 Omnipath 10783893 9721103 16007147 12138192 7796813 12403772 10990461 10421793 11815618 8657102 10398585 8601309
RNF8 XRCC6 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
USP5 UBC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 19285159 20622874 22878415 26235645 18482987 19373254 16007098 31663737 25970461 27848959 17550899 26876099 24681967 23314748 17980597 16564012 27066941 17692280 22428841 8841133 22216260 24424410 34648286
VHL UBE2D3 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10878807 9891082 12101228 10535940 12538644 11454738 22286099 10973499
DDB2 UBE2C â—¼   KO_DOWN_REGULATES ✅ - -1.02 1.01 PKG 28854368
XRCC4 CDC20 â—¼   KO_UP_REGULATES ✅ + 1.12 1.12 PKG 28854368
DDB2 PDCD4 â—¼   KO_UP_REGULATES ✅ + 1.13 1.13 PKG 28854368
XRCC4 PDCD4 â—¼   KO_DOWN_REGULATES ✅ - -1.6 1.59 PKG 28854368
EXO1 UBE2S â—¼   KO_UP_REGULATES ✅ + 1.94 1.94 PKG 28854368
DDB2 DDB2 â—¼   KO_DOWN_REGULATES ✅ - -5.71 5.7 PKG 28854368
XRCC4 XRCC4 â—¼   KO_DOWN_REGULATES ✅ - -6.32 6.31 PKG 28854368