GSK3A
|
AXIN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5219669
17318175
|
GSK3B
|
AXIN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5219694
17318191
|
GSK3B
|
CTNNB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5219694
17318191
|
ARF3
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
WNT3A
|
AXIN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
10428961
8666229
|
BCL2
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
PPP2CA
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
PPP2R5A
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
SPRED1
|
AXIN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
FZD5
|
AXIN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
10428961
8666229
|
CDC20
|
AXIN2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
8375353
22322943
|
PPP2CA
|
BCL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5217079
15225643
|
BCL2
|
PPP2CA
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
5217079
15225643
|
DAPK1
|
BCL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
19395874
|
BCL2
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15210690
|
PRR14
|
CBX5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
MYC
|
CBX5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
CCNG1
|
PPP2R1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5219546
17245430
|
PPP2R1A
|
CDK4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
8208439
17540176
|
PPP2R1B
|
CDK4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
8208439
17540176
|
CHEK2
|
PTTG1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16647857
|
SPRED1
|
CTNNB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
CTNNB1
|
PTTG1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15514942
16705313
|
PPP2CA
|
CTNNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10644691
19061640
|
DAPK1
|
EPHA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
29513927
201700444
|
PPP2R1B
|
MAP3K3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
PPP2R1A
|
MAP3K3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
PPP2CA
|
MAP3K3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
20448038
|
PPP2R1A
|
PPFIA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
8213804
18782753
|
PPP2R5D
|
PPFIA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
PPP2R5A
|
PPP2CA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
8287037
7592815
|
PPP2R5C
|
PPP2R1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5219546
17245430
|
PPP2R5A
|
PPP2R1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5219546
17245430
|
PPP2R5C
|
PPP2R1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16456541
5218298
|
PPP2R5A
|
PPP2R1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
8213804
18782753
|
PPP2R5D
|
PPP2R1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
8208439
17540176
|
RANGAP1
|
PPP2R5A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
SET
|
PPP2R5A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5219540
17245428
|
PPP2R5A
|
SPRED1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
PPP2CB
|
PPP2R5A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
809.0
|
0.8
|
STRING
|
36370105
|
LRP6
|
AXIN1
|
â—¼ RELOCALIZATION
|
✅
|
-
|
0.81
|
0.81
|
Signor
|
18632848
|
AXIN1
|
AXIN2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
20128690
22682247
|
PPP2CA
|
PPFIA1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.82
|
0.82
|
mint
|
27880917
|
PPP2CA
|
PPP2R1A
|
â—¼ CORRELATES
|
|
+
|
0.82
|
0.82
|
CCLE
|
31978347
|
PTTG1
|
CDC20
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
23239745
23007648
27939943
29517484
25161877
25383541
20080579
11553328
25669885
27509861
27114510
23091007
24930963
32152539
16455800
17360335
22193957
26912231
19117984
27522463
31455778
32307883
32076268
11562349
26387737
24781523
|
SGOL1
|
SET
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
26496610
16541025
|
LRP6
|
WNT3A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
833.0
|
0.83
|
STRING
|
36370105
|
AXIN2
|
CTNNB1
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
0.83
|
0.83
|
Signor
|
11940574
|
CDC27
|
PTTG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
835.0
|
0.83
|
STRING
|
36370105
|
PPP2R5C
|
SGOL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
835.0
|
0.83
|
STRING
|
36370105
|
GSK3B
|
CTNNB1
|
â—¼ PHOSPHORYLATION
|
✅
|
-
|
0.84
|
0.84
|
Signor
|
16293724
|
AXIN2
|
APC
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
+
|
0.84
|
0.84
|
Signor
|
10911903
|
PTTG1
|
CDC27
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
16479161
21186364
27114510
16921029
24781523
22193957
20080579
|
PPFIA1
|
PPP2R5D
|
â—¼ PHYSICAL_INTERACTION
|
|
|
860.0
|
0.86
|
STRING
|
36370105
|
AXIN1
|
PPP2CA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
868.0
|
0.86
|
STRING
|
36370105
|
LRP6
|
GSK3A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
30824926
16365045
|
GSK3A
|
AXIN2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
33961781
23602568
30824926
|
ESPL1
|
PTTG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
MYC
|
GNL3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
30415952
29467282
17353931
|
CDC20
|
PPP2CA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
872.0
|
0.87
|
STRING
|
36370105
|
PPP2CB
|
PPP2R5C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
873.0
|
0.87
|
STRING
|
36370105
|
CDC20
|
UBE2S
|
â—¼ PHYSICAL_INTERACTION
|
|
|
880.0
|
0.88
|
STRING
|
36370105
|
PPP2R1B
|
PPP2R2D
|
â—¼ PHYSICAL_INTERACTION
|
|
|
882.0
|
0.88
|
STRING
|
36370105
|
CDC27
|
UBE2S
|
â—¼ PHYSICAL_INTERACTION
|
|
|
885.0
|
0.88
|
STRING
|
36370105
|
MYC
|
GSK3B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
16247449
20713710
19131971
21150319
31638140
29467282
11877389
33541412
14563837
8247524
|
GSK3B
|
LRP6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
19107203
16890161
16365045
|
MYC
|
CDK4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
22094256
28205554
21988832
28628118
|
PPP2R1B
|
PPP2CA
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.89
|
0.89
|
mint
|
8392071
8286818
|
CBX5
|
PRR14
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HuRI
|
32296183
|
GSK3B
|
FZD5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
MYC
|
GSK3B
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12695333
|
PPP2R1A
|
SGO1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16541025
16541024
16580887
|
AXIN1
|
APC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
20128690
29045831
29713058
9734785
19131971
10811618
26496610
23277359
10228155
16199882
17510365
22682247
18786926
|
AXIN2
|
APC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10966653
10911903
9554852
|
MYC
|
APP
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12695333
|
AXIN1
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
19131971
20399964
|
MYC
|
AXIN2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
19149881
24299953
|
PPP2CB
|
AXIN2
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
3.0
|
0.9
|
intact
|
1203359
10698523
8285077
|
CTNNB1
|
BCL2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
17404573
16288908
12782598
|
CDC20
|
BUB1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
33961781
25502805
11702782
21407176
23643811
23239745
29973720
23007648
22566641
27939943
12196507
18591651
19098431
24464857
25383541
26960431
23443559
25669885
22000412
26986935
29432156
20512932
20733051
21926987
25012665
25833949
27694884
11907259
18997788
25482201
25750436
24581499
23091007
27114510
19820702
25306918
21300909
32707033
32152539
11535616
20360068
22100920
33310066
17598981
25852190
25673878
28404789
24151075
23345399
17360335
22193957
28514442
21335556
26912231
23791783
26811472
25246557
11274370
21937719
11030144
19407811
25241761
28096334
20212161
25505175
30341343
|
MYC
|
CBX5
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12747840
|
PPP2R2D
|
DAPK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
085076
20220139
8204016
|
DZIP1
|
PPP2R5D
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
274761
21878643
8287248
|
DZIP1
|
PPP2R5C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
274761
21878643
8287248
|
DZIP1
|
PPP2R5A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
274761
21878643
8287248
|
PTTG1
|
ESPL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
33961781
20360068
26496610
26186194
24781523
25750436
17604273
28514442
19117984
|
FZD5
|
LRP6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12857724
18077588
|
MYC
|
GNL3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12747840
|
PPP2R5D
|
MAP3K3
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
3.0
|
0.9
|
intact
|
16407301
509249200
8007293
|
MAP3K3
|
PPP2R5A
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
3.0
|
0.9
|
intact
|
16407301
509249200
8007293
|
SET
|
PPP2CA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
9353299
21806989
|
PPP2R1A
|
PPP2CB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
15936019
16039140
|
APC
|
GSK3B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
910.0
|
0.91
|
STRING
|
36370105
|
AXIN1
|
GSK3A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
914.0
|
0.91
|
STRING
|
36370105
|
CDC20
|
PTTG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
914.0
|
0.91
|
STRING
|
36370105
|
CTNNB1
|
GSK3A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
916.0
|
0.91
|
STRING
|
36370105
|
AXIN1
|
LRP6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
916.0
|
0.91
|
STRING
|
36370105
|
AXIN2
|
GSK3B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
920.0
|
0.92
|
STRING
|
36370105
|
PPP2R1A
|
PPP2CB
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.92
|
0.92
|
mint
|
5217765
15936019
|
PPP2R5C
|
PPP2CA
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.93
|
0.93
|
mint
|
6549523
1328865
|
PPP2R1B
|
PPP2R5C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
939.0
|
0.93
|
STRING
|
36370105
|
CTNNB1
|
AXIN1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.94
|
0.94
|
mint
|
5219694
17318191
|
PPP2R1B
|
PPP2R5D
|
â—¼ PHYSICAL_INTERACTION
|
|
|
942.0
|
0.94
|
STRING
|
36370105
|
PPP2CA
|
SGOL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
953.0
|
0.95
|
STRING
|
36370105
|
PPP2CB
|
PPP2R2D
|
â—¼ PHYSICAL_INTERACTION
|
|
|
955.0
|
0.95
|
STRING
|
36370105
|
CTNNB1
|
APC
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.96
|
0.96
|
mint
|
36950384
|
PPP2CB
|
PPP2R1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
960.0
|
0.96
|
STRING
|
36370105
|
CTNNB1
|
GSK3B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
969.0
|
0.96
|
STRING
|
36370105
|
AXIN2
|
CTNNB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
969.0
|
0.96
|
STRING
|
36370105
|
BUB1B
|
CDC27
|
â—¼ PHYSICAL_INTERACTION
|
|
|
987.0
|
0.98
|
STRING
|
36370105
|
PPP2R1A
|
PPP2R1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
PPFIA1
|
PPP2CA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
993.0
|
0.99
|
STRING
|
36370105
|
PPFIA1
|
PPP2R1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
993.0
|
0.99
|
STRING
|
36370105
|
AXIN1
|
CTNNB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
PPP2CA
|
PPP2R5D
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
PPP2CB
|
PPP2R5D
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
PPP2R1A
|
PPP2R5C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
PPP2R1A
|
PPP2R5A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
PPP2R1A
|
PPP2R2D
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
PPP2R1A
|
PPP2R5D
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
PPP2R1B
|
PPP2R5A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
PPP2CA
|
PPP2R2D
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
AXIN1
|
GSK3B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
MAX
|
MYC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
PPP2CA
|
PPP2R1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
PPP2CA
|
PPP2R1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
PPP2CB
|
PPP2R1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
APC
|
CTNNB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
0.99
|
STRING
|
36370105
|
BUB1B
|
CDC20
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
0.99
|
STRING
|
36370105
|
CDC20
|
CDC27
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
0.99
|
STRING
|
36370105
|
PPP2CA
|
PPP2R5C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
0.99
|
STRING
|
36370105
|
PPP2CA
|
PPP2R5A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
0.99
|
STRING
|
36370105
|
PPP2R5A
|
GSK3A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
19131971
10026142
10995457
18042541
18559511
16680151
|
PPP2R5C
|
GSK3A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
19131971
11897496
10026142
10995457
18042541
8524413
18559511
16680151
|
AXIN1
|
GSK3A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
9501208
9601641
9482734
11707456
10196136
17318175
|
PPP2R5D
|
GSK3A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
19131971
10026142
10995457
18042541
18559511
16680151
|
GSK3A
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
12.0
|
1.0
|
Omnipath
|
11018017
17081983
2663470
11877389
14563837
8247524
16023596
15150404
|
GSK3A
|
CTNNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
9601641
9482734
12051714
12000790
11818547
12114015
|
GSK3A
|
LRP6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
24642411
21606194
21709260
14731402
20229235
30824926
16365045
19366350
21406690
17318175
|
GSK3B
|
WNT3A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
11336703
17529994
18077588
17569865
|
PPP2R5A
|
GSK3B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
19131971
10026142
10995457
18042541
18559511
16680151
|
AXIN2
|
GSK3B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
15611123
10966653
10911903
888800000547
9554852
22745173
9566905
22322943
|
PPP2R5D
|
GSK3B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
19131971
10026142
10995457
18042541
18559511
16680151
|
GSK3B
|
AXIN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
102.0
|
1.0
|
Omnipath
|
20128690
16944320
11738041
20043192
12511557
11967263
16890161
22613765
14663202
23602568
8524413
24451375
19303846
12554650
8638126
22509369
18593713
16199882
21988832
23331499
19759537
10428961
9482734
22270359
19202075
17570479
16293724
15327768
10581160
17318191
11487578
22773187
26496610
16568235
17318175
19131971
15465828
26912724
25241761
24976009
21242974
22682247
10228155
23579495
12584189
23959799
15020233
10421629
10488109
11278246
9501208
18632848
10481074
10535959
10318824
9554852
17601533
9832503
21502811
9734785
23455922
|
GSK3B
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
73.0
|
1.0
|
Omnipath
|
17081983
18463697
21646472
30037819
26751215
25647305
2663470
20080742
19797085
30003124
16855632
12040186
18679417
11018017
23331499
29229669
16611981
21071413
24265759
20068231
10671551
16039586
17570479
16023596
29258530
12615961
18669648
21113395
22461507
19131971
8247524
16247449
20604938
19575820
15150404
22481935
23668310
19651622
17444818
23964270
20537194
22893788
27684546
24662831
25333250
20399964
11877389
14563837
18408012
17052453
18455992
15212693
16371461
11274345
|
GSK3B
|
APC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
28.0
|
1.0
|
Omnipath
|
16944320
11166179
16799642
11967263
14663202
8524413
12554650
8638126
17910481
15327768
10581160
11487578
17318175
15465828
10228155
15020233
10421629
10698523
9832503
|
GSK3B
|
CDK4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
13.0
|
1.0
|
Omnipath
|
11152665
20537194
10385618
11124803
12969793
19757160
16732330
10486203
16039586
14536078
18167338
12459251
12615961
|
GSK3B
|
LRP6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
22357953
23331499
19107203
21606194
16890161
21709260
16340998
16365045
19366350
21406690
16341017
17318175
|
GSK3B
|
CTNNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
183.0
|
1.0
|
Omnipath
|
22415718
11967263
27158593
29455668
19303846
19797085
8638126
19293931
23056571
22662165
25352148
16611981
27068260
28337019
10671551
21743491
20688898
16293724
23721711
23552738
18687691
28977889
19622173
12051714
25241761
27683053
28549350
22699938
19565571
23076981
21562161
19575820
20219694
20537194
10330181
21986938
29183346
27773936
11251183
19711366
21035499
19675674
7542250
23151663
24451375
14663202
23804296
8524413
25639486
23770025
18070361
26892600
30143633
9233789
19667122
27507058
19061640
19223551
29387014
23331499
16199882
11533658
18644116
24501426
24913829
11835406
17318191
26014148
25366337
28183999
22640743
26910375
12000790
12114015
18387957
19107203
9832503
16371461
29805709
27462866
20137080
27902311
12040186
19576224
25644994
12615961
19060929
25897075
12851486
15465828
17053159
18952601
10228155
15020233
17444818
20140245
26453498
17052453
16944320
24015932
23602568
24975844
24931005
28948000
20080742
23209942
30271168
28220106
16520547
28430641
11818547
25546293
27672271
11955436
11154277
26373837
16039586
23778311
28697793
20302655
25136145
26905812
22216350
8666229
12957350
23109003
10074433
28529629
20215423
21329734
11254732
9501208
27098453
27281614
30279527
19631635
25482131
18455992
24403311
11274345
|
AXIN1
|
WNT3A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
11336703
17529994
18077588
17569865
|
WNT3A
|
CTNNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
31.0
|
1.0
|
Omnipath
|
21108734
7641885
15265686
19718039
21602792
210606194
8655584
19705439
19029934
20093472
17430994
21606194
17884187
14747478
22017973
22433869
17143292
20006983
24535659
19072724
14704854
16965538
16443747
22007144
16547521
19020754
20940130
21640127
21087212
17127310
21796133
|
WNT3A
|
LRP6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
26.0
|
1.0
|
Omnipath
|
23400998
21078818
19339249
12897152
14739301
24265322
16890161
22726442
19910923
15578921
20093360
22491013
18772438
21944579
|
WNT3A
|
FZD5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
17117926
22753465
24032637
|
APC
|
AXIN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
26.0
|
1.0
|
ACSN
|
10421629
10581160
11487578
11955436
11967263
12051714
12554650
15001769
15327768
16039586
16288291
16940750
17143292
17318175
17936032
19619488
19751508
20006983
20705860
22270359
23343194
24023259
25730849
7542250
8638126
8666229
|
MYC
|
APC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
22911891
12695333
|
AXIN1
|
APC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
16199882
20128690
19131971
11297546
9554852
22682247
10228155
26496610
23277359
10811618
9734785
|
PPP2CA
|
APC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
10698523
|
APC
|
CTNNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
60.0
|
1.0
|
Omnipath
|
17145710
10545404
11166179
8259519
7890674
22083140
27902311
8638126
16212417
16798748
19061640
9286858
15327769
9482734
11533658
22056988
19576224
15327768
17318191
26496610
12628243
15355978
9065403
11712088
25241761
26910375
22682247
9065401
12000790
11707392
20219694
9707618
23840886
15525529
11251183
8628279
19631635
11972058
21664290
|
MYC
|
AXIN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
22.0
|
1.0
|
ACSN
|
11274345
11283614
16713974
16940750
17558397
17873522
19131971
19366350
19751508
19836308
20027199
20237412
20551172
20581311
20713526
21406394
2191300
22067385
22270359
23732914
25002027
26885856
|
MYC
|
AXIN1
|
â—¼ SHARES_COMPLEX
|
|
|
22.0
|
1.0
|
ACSN
|
11274345
11283614
16713974
16940750
17558397
17873522
19131971
19366350
19751508
19836308
20027199
20237412
20551172
20581311
20713526
21406394
2191300
22067385
22270359
23732914
25002027
26885856
|
PPP2CA
|
AXIN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
19131971
23331499
10644691
9920888
10026142
11742073
10995457
18042541
18559511
16680151
10421629
|
LRP6
|
AXIN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
20.0
|
1.0
|
Omnipath
|
20128690
23331499
8666229
12897152
10428961
24976009
16890161
18632848
22682247
23959799
16340998
18988627
19107203
|
PPP2R5D
|
AXIN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
19131971
10026142
10995457
18042541
18559511
16680151
|
AXIN1
|
CTNNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
52.0
|
1.0
|
Omnipath
|
20128690
20531388
16890161
27902311
22509369
18593713
16199882
23331499
9482734
21071413
26496610
19244247
22773187
17318191
10196136
18988627
17208333
19131971
24976009
22682247
10228155
12805222
12000790
10488109
9501208
9601641
18632848
9554852
19166851
23959799
12421363
9734785
11940574
|
CTNNB1
|
AXIN2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
24447505
15473860
11809809
22615875
11809808
12711682
11940574
|
CTNNB1
|
AXIN2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
17.0
|
1.0
|
Omnipath
|
10966653
19751508
7542250
8666229
17143292
11955436
11967263
23343194
22270359
9554852
22699938
16039586
16940750
9566905
19619488
15766563
12051714
|
MYC
|
BCL2
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
17.0
|
1.0
|
ACSN
|
11274345
11283613
11283614
11704864
17055429
17558397
17873522
20027199
20237412
20551172
20581311
20713526
21406394
2191300
22067385
25002027
28536364
|
MYC
|
BCL2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
8036017
17404573
12695333
24167291
18809243
19201832
16316993
19649202
|
PPP2CA
|
BCL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
15225643
9852076
|
PPP2CB
|
BCL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
15225643
9852076
|
BUB1B
|
CDC20
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
63.0
|
1.0
|
Omnipath
|
11535616
23443559
11030144
25383541
19098431
23239745
18997788
22000412
15525512
25750436
12196507
16647857
23791783
25482201
25505175
25502805
22100920
25246557
20512932
11907259
25852190
21937719
11702782
20733051
25669885
25306918
19820702
22566641
26811472
25241761
25833949
25012665
27114510
24464857
21407176
17598981
23643811
19407811
23091007
17360335
11274370
18591651
24581499
20360068
26986935
31515488
25673878
21926987
24151075
|
CDC27
|
CDC20
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
25156254
12956947
9736712
17443186
22014574
9637688
24781523
16189514
14561775
12196507
|
CDC20
|
PTTG1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
20.0
|
1.0
|
Omnipath
|
11535616
17303408
8824189
15279786
12640463
7575488
10477750
17376779
19182530
15024386
9790499
18590585
17498870
17660363
15592459
11553328
19154723
11402067
19503101
18022367
|
CDC20
|
CDC27
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
25156254
12956947
9736712
17443186
22014574
9637688
24781523
16189514
14561775
12196507
|
CDC27
|
PTTG1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
11535616
17303408
8824189
15279786
12640463
7575488
10477750
17376779
19182530
15024386
9790499
18590585
17498870
17660363
15592459
19154723
11402067
19503101
18022367
|
MYC
|
CDK4
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
15208653
12835716
24951594
21384303
14519204
22395148
10688915
17728244
11983916
18414489
|
MYC
|
CDK4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
21988832
11602341
17093053
22094256
|
PPP2CB
|
CHEK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
16596250
15380617
|
PPP2CA
|
CHEK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
16596250
15380617
|
CHEK2
|
PPP2R5C
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
15380617
23178491
|
CTNNB1
|
MYC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
21533051
19778454
16510874
12095419
17360646
18852287
15576399
19561604
20300972
19662654
15579438
17724465
9727977
24447505
18679417
12907606
|
LRP6
|
CTNNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
30.0
|
1.0
|
Omnipath
|
7641885
15265686
19718039
21602792
210606194
8655584
19705439
19029934
20093472
17430994
21606194
17884187
14747478
22017973
22433869
17143292
20006983
19072724
14704854
25088803
16965538
16443747
22007144
16547521
19020754
20940130
21640127
21087212
17127310
21796133
|
FZD5
|
CTNNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
29.0
|
1.0
|
Omnipath
|
7641885
15265686
19718039
21602792
210606194
8655584
19705439
19029934
20093472
17430994
21606194
17884187
14747478
22017973
22433869
17143292
20006983
19072724
14704854
16965538
16443747
22007144
16547521
19020754
20940130
21640127
21087212
17127310
21796133
|
CTNNB1
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
23.0
|
1.0
|
Omnipath
|
19751508
7542250
11967263
22290435
19623618
16574648
23343194
11955436
22270359
22761862
16039586
15810077
17143292
12051714
8666229
22943793
15576399
21151179
16940750
17306568
17666529
21285352
19619488
|
DAPK1
|
PPP2CB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
ACSN
|
12598906
17703233
18582460
19543238
20495383
21172648
21172653
|
DAPK1
|
PPP2CB
|
â—¼ SHARES_COMPLEX
|
|
|
7.0
|
1.0
|
ACSN
|
12598906
17703233
18582460
19543238
20495383
21172648
21172653
|
EIF2AK2
|
PPP2R5A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
18957415
10866685
|
PTTG1
|
ESPL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
15678131
15880121
|
PPP2CA
|
KSR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
18039929
16680151
10995457
18042541
18588945
|
MYC
|
MAX
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
ACSN
|
11274345
12040186
15121849
16908182
2006410
8425218
|
MYC
|
MAX
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
ACSN
|
11274345
12040186
15121849
16908182
2006410
8425218
|
MYC
|
MAX
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
10508165
15665468
8385351
8649388
8521822
22384171
1406956
17341548
|
MAX
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
90.0
|
1.0
|
Omnipath
|
17145710
16287840
25609649
12821782
16606833
16596619
21807113
25522242
20691906
19578763
24951594
8224841
17643117
9528857
12391307
16705173
21150319
10229200
21988832
15572685
9680483
2006410
17314511
14749374
12553908
17289033
17418410
19623651
12824180
17157259
12584560
26496610
20946988
20936779
8425218
23816886
17353931
10319872
17471507
18003922
16140957
20382893
12660246
8266081
7565735
32296183
10465786
26267534
17072308
27705803
9184233
18620061
10918583
17700062
10593926
10611234
16352593
9708738
|
PPP2CB
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
19131971
10026142
10995457
18042541
18559511
16987807
16680151
15048125
|
PPP2R5D
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
19131971
10026142
10995457
18042541
18559511
16680151
|
PPP2CA
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
19131971
10026142
10995457
18042541
18559511
16680151
15048125
|
PPP2R5A
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
19131971
10026142
10995457
18042541
18559511
16680151
|
PPP2R1B
|
PPP2CA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
18715871
17540176
19114990
|
PPP2R5C
|
PPP2CA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
18782753
15380617
1328865
28330616
16456541
11929880
10675325
19156129
8703017
7592815
|
PPP2R1A
|
PPP2CA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
35.0
|
1.0
|
Omnipath
|
21159657
23443559
19818709
19293187
24841198
28330616
18715871
19915589
18782753
33633399
17274953
26496610
17540176
15761952
17374643
17529992
22379092
17055435
8617797
12370081
17632056
16039140
16769727
19156129
|