Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list
Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins
Filter Graph:

0.5
Layout:
  🔂

Click a node or edge for more data...
Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
SGO1 RPS15 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PLK1 SGO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18331714
CDK1 WAPL â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 21878504 21987589
AURKA CDK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1001737 24358021
CDK1 CDCA5 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 21878504 21987589
PPP2R1A CDK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8208439 17540176
CDK1 PDS5A â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 21878504 21987589
CDK1 PDS5B â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 21878504 21987589
PLK1 SMC1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11970886
PPP2R5A PPP2CA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8287037 7592815
PPP2R5A PPP2R1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219546 17245430
SET PPP2R5A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219540 17245428
CDCA5 PDS5B â—¼   PHYSICAL_INTERACTION 811.0 0.81 STRING 36370105
CDCA5 WAPL â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31010829 26496610
PPP2CA PPP2R1A â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
AURKA WAPL â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
STAG2 PDS5B â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 31010829 29867216 15855230 17113138
PDS5B RAD51 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 27924011 22293751
SMC1A PLK1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 27173435 26344197
CDCA5 PDS5A â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
CDCA5 RAD21 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
CDCA5 STAG2 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
CDCA5 SMC1A â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
STAG2 WAPL â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 29263825
WAPL SMC1A â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 20360068 17112726 26496610 23242214 31010829 17113138
WAPL PDS5B â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 20360068 17112726 26496610 31010829 17113138
WAPL STAG2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 25173175 20360068 17112726 29867216 26496610 31010829 29263825 17113138
STAG2 SMC1A â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 17112726 10931856 29867216 26344197 24981860 26496610 23242214 31010829 19629043 29263825 17113138
PPP2R1A SGO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16541025 16541024 16580887
WAPL PDS5A â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 20360068 17112726 26496610 31010829 21111234 17113138
WAPL RAD21 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 25173175 20360068 17112726 26496610 22145905 31010829 28514442 17113138
PLK1 WAPL â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 11509732 15737063 21987589
PLK1 CDCA5 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 11509732 15737063 21987589
PLK1 PDS5A â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 11509732 15737063 21987589
PLK1 PDS5B â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 11509732 15737063 21987589
SET PPP2CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 9353299 21806989
PDS5A STAG2 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
PDS5A SMC1A â—¼   PHYSICAL_INTERACTION 959.0 0.95 STRING 36370105
PDS5B SMC1A â—¼   PHYSICAL_INTERACTION 959.0 0.95 STRING 36370105
STAG2 RAD21 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 17962804 6178082
PDS5B RAD21 â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
PDS5A RAD21 â—¼   PHYSICAL_INTERACTION 962.0 0.96 STRING 36370105
SMC1A STAG2 â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
PPP2CA PPP2R5D â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PPP2R1A PPP2R5A â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PPP2R1A PPP2R5D â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RAD21 SMC1A â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RAD21 STAG2 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PPP2CA PPP2R1A â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PPP2CA PPP2R5A â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
CDK1 SGO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 24055156 29971233 26365192 29312936 23242214
NEK2 SGO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 22201785 18669648 17621308
WAPL RAD21 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 17145710 17112726
AURKA PLK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 63.0 1.0 Omnipath 18566290 23618492 27721411 24338364 15713655 28126323 34260926 19364923 33805672 33771996 32284347 27504491 33898950 10980711 26206521 21474997 32060423 27662907 28994651 33963314 18615013 23695676 34197606 18669648 25925375 26114094 19228686 28591578 22281053 18691976 20603326 15611664 27068477 27908669 26919439 26012549 18477460 34140642 25660017 27899378 19369195 21454580 25871386 24349352 12207013 20869364 11854496 20633640 28351953 24667170 25042804
CDK1 PLK1 â—¼   ENZYMATIC_REACTION ✅ 22.0 1.0 ACSN 12124778 14551205 14614141 15242590 15279786 15375219 15377654 15485915 15917306 16713580 16818604 17303408 17596790 17660363 18414028 18543256 18590585 18995830 19652693 19686080 7575488 9892021
CDK1 KIF2C â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 20368358 29230353
CDK1 PLK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 19652693 18590585 7575488 17303408 12124778 17764786 17660363 15279786 15917306
PLK1 RAD21 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 15737063 25299182 18931676 18616427 11073952 19270156 19622404 19686080
PLK1 STAG2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18931676 18616427 19270156 19622404 19686080
PPP2R1A PPP2CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 35.0 1.0 Omnipath 21159657 23443559 19818709 19293187 24841198 28330616 18715871 19915589 18782753 33633399 17274953 26496610 17540176 15761952 17374643 17529992 22379092 17055435 8617797 12370081 17632056 16039140 16769727 19156129
STAG2 RAD21 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 17145710 28430577 12034751 11590136 25173175 22885700 29263825
CBX1 CBX1 â—¼   KO_DOWN_REGULATES ✅ - -2.99 2.98 PKG 28854368