Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
HSPA8 VASP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
AURKA CDK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1001737 24358021
MBD2 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 23011797 16052033
BUB1B CDK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11285280 10679238
CDKL5 TACC3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
VPS37C CEP55 â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 6169256 17853893
CEP55 TACC3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
TACC3 CKAP5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21297582 8144895
KLHL38 OIP5 â—¼   PHYSICAL_INTERACTION 0.8 0.8 HuRI 32296183
UBE2S FZR â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 25306923 32905768 19822757 23708001 25306918
FZR UBE2C â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 21700221 23707760 25306923 23670162 32905768 19822757 18485873
FZR BUB1B â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 23091007 25505175 33306668
CDC27 UBE2C â—¼   PHYSICAL_INTERACTION 816.0 0.81 STRING 36370105
SNX20 HSP7C â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
BRCA1 HSP7C â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26831064 9738006
HSP7C TACC3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
HSP7C CKAP5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
MS18B TACC3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
KIME TACC3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CRIS2 TACC3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CORO6 TACC3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
TACC3 ENAH â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 26496610
EVL TACC3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
KAT2B KAT2A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 10373431 24981860
SPERT KIF11 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SPERT TACC3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RNF20 TACC3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HuRI 32296183
SNP29 NDEL1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
SNP29 TACC3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
ARNT HSP7C â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 27684187
FZR CKS2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 33306668
CDCA3 FZR â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194 33306668
MS18B UBE2T â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
PKHO2 TACC3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
SLAI2 TACC3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26496610
HMMR BRCA1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 22110403 25184681 26831064
GDF15 TACC3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HuRI 32296183
CDK1 CDC25C â—¼   PHOSPHORYLATION ✅ + 0.83 0.83 Signor 8119945
CDC25C CDK1 â—¼   DEPHOSPHORYLATION ✅ + 0.83 0.83 Signor 19574738
CDK1 FZR â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 33961781 28514442 20581839 33306668
TACC3 FZR â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 19823035 25375378
NDEL1 TACC3 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 17060449 32296183
BUB1B FZR1 â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
FZR1 UBE2S â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
TACC3 TBC1D22B â—¼   PHYSICAL_INTERACTION 0.85 0.85 HuRI 32296183
HSP7C VASP â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 33961781 30021884
FZR AURKA â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 17895985 28205554 30498084 28628118
AURKA BRCA1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 22110403 26831064 14990569
NDEL1 NUP54 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 31413325
TACC3 VASP â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 26496610 34079125
ENAH VASP â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
CQ059 NDEL1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 26186194 32296183
CQ059 KIF11 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 28514442 26186194 34079125
CQ059 CEP55 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 28514442 26186194 34079125
CQ059 TACC3 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 26186194 34079125
CKAP5 SLAI2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 20360068 26496610 30217970 28514442
KAT2B BUB1B â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 24825348 19407811
CKAP5 SLAIN2 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
EVL VASP â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
ENAH EVL â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
ARHGDIG TACC3 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
CDC27 UBE2S â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
KLHL38 TACC3 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
VASP ENAH â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 26344197 21398369 26186194 28514442 34079125
VASP EVL â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 26344197 21398369 26186194 28514442 34079125
FZR CDC27 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 21768287 29700288 11340163 23160376 26963853 9637688 32345958 23670162 12097298 21186364 12797865 17187060 32152539 17609108 25306918 22014574 33306668 12956947 16479161 24100295 23029392 9734353 21986944 20395298 24811168 28514442 30498084 17942546 20663873 21241890 9811605 32076268 18372912 18662541 23972993
CKS2 CDK1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 26344197 25852190 18471975 26496610 26186194 32707033 28514442 23602568 19786724
HSPA8 HSPBP1 â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
AURKA KIF11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15630414 17939994
KAT2A KAT2B â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 23667505 23555303 21559432
AURKA TACC3 â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
CKAP5 TACC2 â—¼   PHYSICAL_INTERACTION 919.0 0.91 STRING 36370105
STMN1 STMN2 â—¼   CORRELATES + 0.92 0.92 CCLE 31978347
AURKA TACC3 â—¼   PHOSPHORYLATION ✅ + 0.93 0.93 Signor 17545617
FZR1 UBE2C â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
CKAP5 TACC3 â—¼   PHYSICAL_INTERACTION 967.0 0.96 STRING 36370105
BUB1B CDC27 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
CDK1 CKS2 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
CDK1 CKS1B â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
CDC27 FZR1 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
BRCA1 AURKA â—¼   PHYSICAL_INTERACTION 8.0 1.0 ACSN 11877377 15459660 19075565 19793801 20011137 20029420 21060331 21337561
BRCA1 AURKA â—¼   ENZYMATIC_REACTION ✅ 8.0 1.0 ACSN 11877377 15459660 19075565 19793801 20011137 20029420 21060331 21337561
AURKA DLGAP5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 15987997 18220336 16631581 19690332 18669648
AURKA BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 22864622 22340593 18026198 24775809 14990569
AURKA TACC3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 23861900 31932847 25596274 26186194 17060449 21297582 20566684 14602875 17545617 23918938 16172205 15687499 30344944 26090906 26134678
AURKA NDEL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 17060449 22864622 24785679 19668197 17545617 20141511 15687499 20688183 19724260
CDK1 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 9244350 21706030 10550055 17570479 19683496 16713569 26745677 32193285 26719576
CDK1 BUB1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 20016069 23637705 29971233 23345399 23079597 26259146 17785528 20633640 19015317 33207204
CDK1 CDC25C â—¼   ENZYMATIC_REACTION ✅ 26.0 1.0 ACSN 1075565 12124778 14551205 14614141 15242590 15279786 15375219 15377654 15485915 15917306 16713580 16818604 17303408 17568790 17596790 17660363 18073536 18414028 18543256 18590585 18786381 18995830 19652693 19686080 7575488 9892021
CDK1 CDC25C â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 64.0 1.0 Omnipath 17349584 17110335 17303408 18073536 1075565 11836499 15279786 8348613 7575488 20668692 24710276 9733650 12036951 20068231 8440392 12742231 32075732 16189514 9141461 16123593 18669648 19652693 18590585 9585407 12814430 10864927 10373560 18691976 11313986 12124778 18786381 17660363 18272572 8119945 15917306 27038604 9268380 17596790 28396830 17568790 19350548 16964243 10037602 18212344 12478465 12766774
CDK1 CDC27 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 19652693 18590585 7575488 16565220 17303408 29084198 33819340 12124778 17570479 17660363 14657031 15279786 15917306
FZR1 CDC27 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 12797865 12956947 23029392 18662541 9637688 15916961 22014574 21241890 10500174 26963853
CDC27 FZR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 12797865 12956947 23029392 18662541 9637688 15916961 22014574 21241890 10500174 26963853
CKS1B CDK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 26186194 19786724 9276444 9774639 23602568 20015071 25416956 7809159 18471975 26496610 25852190 16189514
CDK1 SLBP â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 18490441 23286197 12588979 27773672
CDK1 NDEL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 24785679 17060449 17570479 18347064 12556484 18669648 18809722
CDK1 KIF11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 26615533 19007248 16565220 19691289 19001501 28487562 19664994 20068231 16455663 25660025 19690332 8548803 21522128 19413330 9235942 20068230
CDK1 STMN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 83.0 1.0 Omnipath 17081983 18767875 9731215 20230923 19690332 17693683 11135364 19413330 18187866 19664995 19415658 18578522 16083285 20068231 18452278 94064639 1737801 18491316 18669648 8245003 16427064 93315482 17287340 16094384 19651622 20058876 8376365 8325880 17924679 18220336 19664994 18707149 8125092 8325881 16964243 33839152 18212344
CDK1 CKAP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 19641375 19369249
CDK1 CEP55 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 35.0 1.0 Omnipath 19415658 17081983 29743530 19691289 18767875 18691976 19664994 20068231 18452278 19413330 16964243 18669648 16198290