Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
USP11 CBX2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7998286 20601937
CBX4 USP11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7998286 20601937
RPL21 CENPE â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
CENPE KTN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
SKA1 CENPE â—¼   COLOCALIZATION 2.0 0.8 intact 5219311 17093495
CKS2 CENPE â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12714746
CLASP2 MAPRE1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19638411 19632184
MAD1L1 MAD2L1 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
MAPK1 RPS6KA3 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12832467 16626623
PPP1CA MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12624094 12840032
MAPRE3 MAPRE1 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
MAPRE3 MAPRE2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
NDC80 SKA1 â—¼   COLOCALIZATION 2.0 0.8 intact 5219311 17093495
BUB1 CENPE â—¼   RELOCALIZATION ✅ + 0.8 0.8 Signor 11402067
RAD18 CENPE â—¼   KO_DOWN_REGULATES ✅ - -0.81 0.8 PKG 28854368
DDB2 CENPE â—¼   KO_DOWN_REGULATES ✅ - -0.82 0.81 PKG 28854368
BFSP2 SPAG5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
BFSP2 CENPE â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
BMI1 KTN1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 34316702 24457600
SPAG5 PCM1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26297806 34079125
CENPE BUB1B â—¼   PHYSICAL_INTERACTION ✅ + 0.82 0.82 Signor 12925705
POLB CENPE â—¼   KO_UP_REGULATES ✅ + 0.82 0.82 PKG 28854368
NIN NDC80 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28718761 34079125
NIN PCM1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 30217970 26638075 28718761 34079125
BUB1 MAD2L1 â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
CCND1 CUL1 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
BMI1 CBX2 â—¼   PHYSICAL_INTERACTION 844.0 0.84 STRING 36370105
BUB1 RAE1 â—¼   PHYSICAL_INTERACTION 854.0 0.85 STRING 36370105
RAD18 NKAP â—¼   KO_UP_REGULATES ✅ + 0.85 0.85 PKG 28854368
CENPE PCM1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 26496610 34079125
NDC80 NUF2 â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
MAD2L1 BUB1B â—¼   PHYSICAL_INTERACTION ✅ 0.87 0.87 mint 21772247 8284719
CDR2 KTN1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 27173435
CENPE NUF2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 19779646 17535814
OFD1 PCM1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 24089205 26496610 26638075 34079125
CLASP2 MAPRE1 â—¼   PHYSICAL_INTERACTION 879.0 0.87 STRING 36370105
BUB1B CENPE â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
PAXX CENPE â—¼   KO_DOWN_REGULATES ✅ - -0.89 0.88 PKG 28854368
MAPRE1 MAPRE2 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
PCM1 NDC80 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 27107012 26638075 34079125
POLM CENPE â—¼   KO_UP_REGULATES ✅ + 0.89 0.89 PKG 28854368
BUB1 NDC80 â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
CBX4 BMI1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 22078878 24981860 19636380 20601937 18453536 26496610 17332741 9199346 21282530 34316702 27647897 24457600 27705803 12829790 22325352
MAPK1 RPS6KA3 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
PPP1CA MAPK1 â—¼   DEPHOSPHORYLATION ✅ 3.0 0.9 intact 211739200 12840032 8214413
BUB1 BUB1B â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
BMI1 CBX4 â—¼   PHYSICAL_INTERACTION 919.0 0.91 STRING 36370105
SKP1 CUL1 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 7304783 18818696
BUB1 MAD2L1 â—¼   RELOCALIZATION ✅ + 0.96 0.96 Signor 11402067
MAD2L1 MAD1L1 â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 6785080 18692475
MAD2L1 MAD1L1 â—¼   COLOCALIZATION ✅ 0.98 0.98 mint 21772247 8284719
MAD1L1 MAD2L1 â—¼   COLOCALIZATION ✅ 0.98 0.98 mint 21772247 8284719
NDC80 NUF2 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
MAPRE1 MAPRE3 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
BUB1B MAD2L1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
MAD1L1 MAD2L1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
WRN POLB â—¼   PHYSICAL_INTERACTION 65.0 1.0 ACSN 10858306 11163244 11283614 11948190 12032095 12202749 12637553 14726013 15385537 15385968 15703371 16442856 16449207 16697054 17055429 17088286 17116323 17116881 17638872 17965729 18398454 18524993 18558713 18584027 18809224 19208614 19364882 19490890 19546231 196269035 19748837 19847258 20027199 20064462 20211143 20227374 20510258 20603072 20691907 20713526 21251944 21270334 21376743 2191300 22055391 22469522 22657828 22713970 22743550 22921416 22973052 23082994 23145148 23161013 23253856 23562323 23568489 24036544 24050180 24210699 24684389 24709898 24976506 8264637 8978692
WRN POLB â—¼   SHARES_COMPLEX 65.0 1.0 ACSN 10858306 11163244 11283614 11948190 12032095 12202749 12637553 14726013 15385537 15385968 15703371 16442856 16449207 16697054 17055429 17088286 17116323 17116881 17638872 17965729 18398454 18524993 18558713 18584027 18809224 19208614 19364882 19490890 19546231 196269035 19748837 19847258 20027199 20064462 20211143 20227374 20510258 20603072 20691907 20713526 21251944 21270334 21376743 2191300 22055391 22469522 22657828 22713970 22743550 22921416 22973052 23082994 23145148 23161013 23253856 23562323 23568489 24036544 24050180 24210699 24684389 24709898 24976506 8264637 8978692
CUL1 SKP1 â—¼   PHYSICAL_INTERACTION 26.0 1.0 ACSN 11516665 11900249 12648680 12820959 14536078 15071497 15147722 15340381 15459660 15489953 15668399 15688063 15703371 16697054 17053147 17884153 18636226 18787170 18931676 19150432 19270156 19622404 19686080 19797085 19809470 19847258
CUL1 SKP1 â—¼   SHARES_COMPLEX 26.0 1.0 ACSN 11516665 11900249 12648680 12820959 14536078 15071497 15147722 15340381 15459660 15489953 15668399 15688063 15703371 16697054 17053147 17884153 18636226 18787170 18931676 19150432 19270156 19622404 19686080 19797085 19809470 19847258
MAPK1 CUL1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 31434245 22955283 12748172 16009132
SKP1 CUL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 66.0 1.0 Omnipath 9663463 19945379 12684064 19270694 16759355 23951410 10648623 11961546 26540345 26976582 26474281 17290223 9736735 21169563 14685242 16357137 21145461 29070679 15452136 15966899 12628165 21778237 22474075 16189514 22767593 11359933 9430629 10713156 10023660 10228155 12504026 18818696 9827542 12504025 18094045 10066435 23324393 23770852 9990852 12417738 27705803 9636170 21249194 12904573 34499862 11027288 26725323 20832730 19933270 12609982 10230407
WRN BMI1 â—¼   UP_REGULATES ✅ + 36.0 1.0 ACSN 11283614 12202749 12545156 15155580 15385537 16449207 17055429 17116323 17550342 17965729 18398454 18524993 18558713 18584027 18809224 19490890 20027199 20064462 20691907 20713526 20818389 21376743 21733352 2191300 21919891 22657828 22743550 23082994 23140366 23161013 23253856 23869868 24036544 24050180 24709898 9618481
CENPE BUB1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12925705 10477750 20237434 9763420
MAD1L1 MAD2L1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 34.0 1.0 Omnipath 31467278 32814053 16713569 10660610 21988832 21772247 16189514 26258632 26496610 21525009 25012665 21041666 11459826 11707408 18692475 32296183 15694304 24581499 26986935 29997244 18318601 31515488 22493223
MAPK1 SKP1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 31434245 22955283 12748172 16009132
MAPK1 RPS6KA3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 21988832 18156174 12016217 25241761 12832467 23602568 8939914 10480933 9915826 17906627 10980595 10856237 19282669
WRN CENPE â—¼   KO_UP_REGULATES ✅ + 1.13 1.13 PKG 28854368
DDB2 FADS2 â—¼   KO_DOWN_REGULATES ✅ - -1.25 1.24 PKG 28854368
RAD18 FADS2 â—¼   KO_DOWN_REGULATES ✅ - -1.36 1.35 PKG 28854368
RAD18 PPP1CA â—¼   KO_UP_REGULATES ✅ + 1.72 1.72 PKG 28854368
WRN WRN â—¼   KO_DOWN_REGULATES ✅ - -3.6 3.59 PKG 28854368
PAXX PAXX â—¼   KO_DOWN_REGULATES ✅ - -3.91 3.9 PKG 28854368
RAD18 RAD18 â—¼   KO_DOWN_REGULATES ✅ - -4.39 4.38 PKG 28854368
DDB2 DDB2 â—¼   KO_DOWN_REGULATES ✅ - -5.71 5.7 PKG 28854368
POLB POLB â—¼   KO_DOWN_REGULATES ✅ - -7.24 7.23 PKG 28854368