Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
NHEJ1 XRCC4 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
FADS2 CLGN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
FADS2 LELP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
FADS2 APOB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PSEN1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21163940 114280
FADS2 CCDC110 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
SREBF1 FADS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12147235 11792729
GPBP1L1 FADS2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
FADS2 SPDL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
RXRG PPARA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RAD18 CENPE â—¼   KO_DOWN_REGULATES ✅ - -0.81 0.8 PKG 28854368
DDB2 CENPE â—¼   KO_DOWN_REGULATES ✅ - -0.82 0.81 PKG 28854368
SOX2 MYEF2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 23667531 21532573
PPARA RXRG â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 16169070 22205725
RXRG RXRA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
NHEJ1 FADS2 â—¼   KO_UP_REGULATES ✅ + 0.84 0.84 PKG 28854368
NHEJ1 TDG â—¼   KO_UP_REGULATES ✅ + 0.86 0.86 PKG 28854368
RAD18 CD81 â—¼   KO_DOWN_REGULATES ✅ - -0.88 0.87 PKG 28854368
PPARA RXRA â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
XRCC4 NHEJ1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 21070942 31548606 21768349 17567543 26774286 18064046 21349273 29997244 16439205
PPARA APOB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11925428 16542871
RXRA PPARA â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 15888456 12562861 7760852 34081964 10195690 22205725 23711995 16189514
PPARA SREBF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12730331 1273033 21540177
RXRB PPARA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8384714 23331499 11237216
APP PSEN1 â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
NHEJ1 XRCC4 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
EXO5 FADS2 â—¼   KO_DOWN_REGULATES ✅ - -1.0 0.99 PKG 28854368
NHEJ1 XRCC4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 22228831 21349273 18064046 21070942 17567543 29997244 16439205 21768349
PPARA FADS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12562861 11792729 15189125
RXRA PPARA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23331499 10195690 12562861 16189514 11237216 10708554
PPARA RXRG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 22205725 23331499 16169070 15130092
RXRA SREBF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11287605 11694526 17531980 16112614
TREX1 FADS2 â—¼   KO_UP_REGULATES ✅ + 1.0 1.0 PKG 28854368
NHEJ1 CD81 â—¼   KO_DOWN_REGULATES ✅ - -1.02 1.01 PKG 28854368
ERCC6 FADS2 â—¼   KO_UP_REGULATES ✅ + 1.06 1.06 PKG 28854368
XRCC4 FADS2 â—¼   KO_UP_REGULATES ✅ + 1.07 1.07 PKG 28854368
RAD18 CTSF â—¼   KO_UP_REGULATES ✅ + 1.23 1.23 PKG 28854368
ERCC6 ERCC6 â—¼   KO_DOWN_REGULATES ✅ - -1.24 1.23 PKG 28854368
DDB2 FADS2 â—¼   KO_DOWN_REGULATES ✅ - -1.25 1.24 PKG 28854368
XRCC4 TDG â—¼   KO_UP_REGULATES ✅ + 1.27 1.27 PKG 28854368
RAD18 FADS2 â—¼   KO_DOWN_REGULATES ✅ - -1.36 1.35 PKG 28854368
TDG FADS2 â—¼   KO_UP_REGULATES ✅ + 1.44 1.44 PKG 28854368
TDG TDG â—¼   KO_DOWN_REGULATES ✅ - -3.98 3.97 PKG 28854368
RAD18 RAD18 â—¼   KO_DOWN_REGULATES ✅ - -4.39 4.38 PKG 28854368
DDB2 DDB2 â—¼   KO_DOWN_REGULATES ✅ - -5.71 5.7 PKG 28854368
XRCC4 XRCC4 â—¼   KO_DOWN_REGULATES ✅ - -6.32 6.31 PKG 28854368
NHEJ1 NHEJ1 â—¼   KO_DOWN_REGULATES ✅ - -6.47 6.46 PKG 28854368