Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
EP300 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23353771 23285190
AURKA CDK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1001737 24358021
CDK1 PKN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17570479 31981797
PLK1 TP53 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 7266226 19833129
SMARCA2 SPAG5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
SMARCA2 CEP72 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
AURKA TP53 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 14702041 19121998
TP53 GSK3B â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 5216887 14744935
SHANK3 ATN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
SPAG5 ATN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
TSC1 ATN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
ENKD1 SPAG5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
ADAM15 SPAG5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 10531379 5211924
TSC1 SPAG5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
ZGPAT SPAG5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
SHANK3 SPAG5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
ZNF385C SPAG5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
SPAG5 CLASP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20852589 8079981
SPAG5 OGA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
SPAG5 SNAPIN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
CLASP1 MAPRE1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15631994
TSC1 COG6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
GSK3B TSC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15972957 16959574
GSK3B PCM1 â—¼   COLOCALIZATION 2.0 0.8 intact 17139249 5219394
COG6 LGALS14 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
SHANK3 CEP72 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
SHANK3 LINGO1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
BRCA1 CENPF â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26831064 29656893
MARE1 EP300 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30110629 21988832
CQ059 RINT1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 33961781
RINT1 SPAG5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
BFSP2 CENPE â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
BFSP2 SPAG5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
DYL1 SPAG5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33961781 26496610
DTBP1 SPAG5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
RHPN1 SPAG5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
EMIL1 SPAG5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CCD89 SPAG5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CCD22 SPAG5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CSN7B SPAG5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
COG6 SPAG5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
K1467 SPAG5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
TSYL1 SPAG5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
MED21 SPAG5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
TSKS SPAG5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
SPAG5 DISC1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31413325 33961781
SPAG5 PCM1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 26297806
COG6 PKN1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
HAUS1 COG6 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
COG6 CCD22 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
DISC1 SRGP3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31413325 17043677
MED4 HAUS1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 25416956 25281560
CEP44 HAUS1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 25416956 26638075
HAUS1 CQ059 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 32296183
OFD1 MARE1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26496610 26638075
TSKS DTBP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
EMIL1 CE170 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CQ059 CCD22 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 26186194
IQCE TTC23 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 32296183 33961781
CCD89 CEP44 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
PLK1 BRCA1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 25483079 24067368 31730000 29656893
PLK1 SPAG5 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 25659891 27173435 26291670
IFT57 CENPH â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
SRGP3 SPAG5 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
DCTN1 DISC1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 90000000 31413325 17043677
DTBP1 COG6 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
IFT57 COG6 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
IFT57 PCM1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 34079125 19293945 26638075
PCM1 TSYL1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26638075
PCM1 CCD22 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 34079125 33961781 26638075
SPAG5 ZNF572 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HuRI 32296183
PCM1 PLK1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 34079125 23345402 26638075
KRT3 SPAG5 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HuRI 32296183
CENPH SPAG5 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HuRI 32296183
GEM SPAG5 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HuRI 32296183
BFSP2 RINT1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HuRI 32296183
CEP72 PCM1 â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
AURKA BRCA1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 22110403 14990569 26831064
PLK1 DCTN1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 34079125 12852857
OFD1 CEP72 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 26496610 26638075
DYL1 PCM1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 30217970 26496610
CENPE PCM1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 34079125 26496610
GSK3B TP53 â—¼   PHYSICAL_INTERACTION 866.0 0.86 STRING 36370105
BFSP2 CEP44 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 32296183 33961781
IFT57 SPAG5 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 19293945 26186194 33961781
MARE1 SPAG5 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 34079125 29162697 26496610
CQ059 SPAG5 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 34079125 26186194
CCD67 SPAG5 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 24613305 33961781 26186194
CE170 SPAG5 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 26186194 26638075
MARE1 AURKB â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 18477699 19696028
CQ059 DISC1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 32296183 33961781 26186194
PCM1 HAUS1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 34079125 33961781 24981860 26638075
CE170 MARE1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 34079125 26496610 26638075
DTBP1 CQ059 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 34079125 26186194
OFD1 PCM1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 34079125 24089205 26496610 26638075
MED1 MED21 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
AURKA TP53 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
MID1 MID2 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
RINT1 TSHZ3 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
PLK1 OFD1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 26638075 21988832
MED4 PCM1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 34079125 33961781 25281560 26638075
MED1 MED4 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
MED1 BRCA1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15208681 16713569
EP300 PAX6 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 35140242 10506141
AURKA PLK1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 22939629 18615013 18773538
MED1 MED21 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 15989967 24882805 33961781 24981860 22939629
CE170 DISC1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 29961565 90000000 33961781 31413325 17043677
MED21 MED4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 24882805 33961781 24981860 22939629 25281560
OFD1 DYL1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 33961781 27173435 26496610 26638075
KRT75 SPAG5 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
MED21 MED4 â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
EP300 BRCA1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21102443 19887647 10655477 11782371 16713569 21212407 22787115
GSK3B SPAG5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18055457
OGA GSK3B â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
MED1 MED4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 15989967 24882805 20133760 33961781 24981860 22939629 25281560 26344197
PCM1 CEP72 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16189514 23443559 26638075 34079125 26297806 19447967
BRCA1 TP53 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
KRT3 KRT75 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
EP300 TP53 â—¼   POLYUBIQUITINATION ✅ - 0.91 0.91 Signor 12690203
DCTN1 MAPRE1 â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
DCTN1 MARE1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 17828277 26638075 26496610 27173435 34079125 12388762 24997520
SMARCA2 SMARCE1 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
TP53 EP300 â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 16611888 6599495
EP300 TP53 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
BRCA1 AURKA â—¼   PHYSICAL_INTERACTION 8.0 1.0 ACSN 11877377 15459660 19075565 19793801 20011137 20029420 21060331 21337561
BRCA1 AURKA â—¼   PROTEIN_INTERACTION 8.0 1.0 ACSN 11877377 15459660 19075565 19793801 20011137 20029420 21060331 21337561
BRCA1 AURKA â—¼   ENZYMATIC_REACTION ✅ 8.0 1.0 ACSN 11877377 15459660 19075565 19793801 20011137 20029420 21060331 21337561
TP53 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 24.0 1.0 Omnipath 9582019 11295099 18625847 11003642 12802282 16357511 14710355 9619832 19882681 10884389 11384963 11782367 12024039 15735697 12170778 21245169 17993233 12549011 11431698 16229810 18208621 10597265 21742769
AURKA BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 22864622 22340593 18026198 24775809 14990569
CDK1 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 9244350 21706030 10550055 17570479 19683496 16713569 26745677 32193285 26719576
CDK1 TSC1 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 14551205 15279786 17303408 17660363 18414028 18590585 7575488
CDK1 PLK1 â—¼   ENZYMATIC_REACTION ✅ 22.0 1.0 ACSN 12124778 14551205 14614141 15242590 15279786 15375219 15377654 15485915 15917306 16713580 16818604 17303408 17596790 17660363 18414028 18543256 18590585 18995830 19652693 19686080 7575488 9892021
TP53 CDK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 10825186 11593387 12874009 19472317 10514438 11313928 16807237 8270002 17942917 9275177 20395210 11032828 19861536 12889596 19067706
GSK3B CDK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 9832503 17359287
CDK1 TSC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 11444800 14551205 18414028 20006582
CDK1 PLK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 19652693 18590585 7575488 17303408 12124778 17764786 17660363 15279786 15917306
CDK1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 24173284 12767922 1584757 20661218 26029996 2141171 9467949 17570479 20808790 7862459 11327730 11078726 27726420 8357826 16713569 2156209
EP300 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 137.0 1.0 Omnipath 11907332 25545885 21187340 10706102 16438982 10490106 19339993 15542844 23010591 11433299 19608861 17438265 17906639 16024799 9194564 20234175 23402884 12162806 26229107 16959611 15186775 9744860 11070080 17977830 17189186 22266186 20228809 15664194 19805293 25753752 11804596 26625199 27818144 10648616 16928824 9288740 10942770 12724314 23148227 23728348 15965232 19218448 16678111 16782091 20094059 14612423 24821727 10518217 16713569 9891054 25288747 17452980 14759370 19788416 25156994 18931695 22074660 23880760 15337767 15509808 26302407 22731250 18391200 16543236 19234109 21471221 23307557 25867071 12690203 15558054 18612383 23870121 18243116 19217391 22013068 16537920 16611888 18485870 9194565 12660246 9809062 23796514 11359905 12501250 15295102 19407812 25651062 23329847 16135789
TP53 PLK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 17172872 17981789 15024021 22405092 20962589 24076372 23948487 15016801 22184120 19713933 16369493 23474762
AURKA PLK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 63.0 1.0 Omnipath 18566290 23618492 27721411 24338364 15713655 28126323 34260926 19364923 33805672 33771996 32284347 27504491 33898950 10980711 26206521 21474997 32060423 27662907 28994651 33963314 18615013 23695676 34197606 18669648 25925375 26114094 19228686 28591578 22281053 18691976 20603326 15611664 27068477 27908669 26919439 26012549 18477460 34140642 25660017 27899378 19369195 21454580 25871386 24349352 12207013 20869364 11854496 20633640 28351953 24667170 25042804
PLK1 DCTN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 21931181 28415805 23985322 23661607 20679239
PLK1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 22653443 19833129 16753148 23948487
MED1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 15848166 9444950 16713569 11118038
GSK3B TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 23840442 12064478 11709713 9372954 11483158 16552184 17570479 14744935 16713569 21929745 12048243 21900206
AURKA TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 50.0 1.0 Omnipath 24173284 22864622 25217103 24089029 16713569 19413330 25848977 17999753 23565200 25333414 23201157 16552184 10884347 1956339 26186194 29455673 15469940 15749021 18974145 21502403 17287340 28043820 22396649 92065884 12198151 27933271 22852086 12064478 30266789 25398437 17259342 22350019 25634113 14702041
AURKB TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 20959462 27933271 20847049 15469940 32873634 22611192 27496712
DYNLL1 DCTN1 â—¼   PHYSICAL_INTERACTION 28.0 1.0 Reactome 17274799 9490716 10679020 10562278 11306556 24891604 16723730 18086915 17283181 18664496 11035033 25453831 18046453 11285137 19564404 8642258 12198549 15728195 10903204 15878873 7691276 8909537 23839779 9150144 10559986 25233431 10036229 24806965
GSK3B DCX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17570479 21159948